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Applications of Radioisotopes in Cancer Treatment

Did you know in 2022, there were an estimated 20 million new cancer cases and about 9 million cancer-related deaths globally? What’s more staggering is cancer is one of the leading causes of death worldwide and by 2040, the number of new cancer cases annually is forecasted to rise to 29.9 million! Despite being such a fatal condition for humankind, the treatment of cancer is still a dilemma. When you think about cutting-edge treatments for cancer, all we can imagine is complex procedures or advanced technology. However, only a few people know about medical radioisotopes because although they are effective, their production has been a challenge.

Medical radioisotopes are tiny but powerful elements that play a substantial role in the fight against cancer. How? Well, here’s a guide on how these medical marvels work and what their transformative impact on cancer treatment is.

What are Medical Radioisotopes?

Medical radioisotopes are radioactive isotopes used in diagnostic imaging and therapy. Their ability to emit radiation makes them invaluable in pinpointing and treating cancer cells or oncogenic cells. These isotopes are carefully packed based on their properties, such as half-life and type of radiation emitted, so healthcare professionals can target cancerous tissues precisely without damaging any healthy cells.

Lutetium-177: A Game Changer in Therapy

Lutetium 177 production has revolutionized targeted cancer therapy. The isotope is used in therapies like peptide receptor radionuclide therapy (PRRT), where it is attached to a molecule that binds specifically to cancer cells and delivers targeted radiation directly to the cancerous cells.

The beta radiation emitted by this isotope is perfect for this cause because it penetrates tissues just enough to destroy the tumor without excessively harming any surrounding tissues that might be healthy.

Actinium-225

Ac-225 is another promising radioisotope used in cancer treatment, part of a newer class of targeted alpha therapy agents. Unlike beta radiation, Ac-225 emits alpha particles, which have a higher energy and a shorter range. This is beneficial for targeting small clusters of cancer cells or even individual cells that might be resistant to other forms of radiation.

Challenges in Producing Radioisotopes

Yes, medical isotopes can save lives, but their production process is no cakewalk because it requires specialized facilities and complex technology, which is expensive and time-consuming. Besides, the production of these isotopes requires a consistent and reliable supply, which is tough due to the short half-lives of the isotopes and limited production sites. Stringent regulations and quality control are not easy either and the high production costs can also limit the accessibility and affordability for clinicians, researchers, as well as healthcare giants.

Conclusion:

Although the medical application of radioisotopes has been a game-changer in the field of oncology, their production has been limited by technical limitations, waste steam concerns, and supply outages. To combat these issues, Nusano has come up with a wide variety of isotopes for researchers, drugmakers, and clinicians while stabilizing supply chains. Assisting the fight against Cancer, Nusano is helping healthcare leaders meet the increasing need for medical radioisotopes and helping patients worldwide save lives with super-efficient technology. Our technology can produce up to 12 different radioisotopes simultaneously, and this is a major stepping stone needed to advance cancer care.  Source: https://nusanous.blogspot.com/2024/09/applications-of-radioisotopes-in-cancer.html