okay i feel like this would become an AU so under the cut is me rambling:
Squeaky got WAYYYYY too controlling over Twobrains' body just for some cheese and nuked the whole city. Wordgirl DOESNT forgive him for this even if she knows it was because of Squeaky.
i feel like twobrains would try and find ways to apologize to her and so many people by retiring his villianous ways and doing good (which Squeaky doesn't like at all). Squeaky would get so mad that Twobrains tries to find a way to stop or remove Squeaky while trying to do good.
Most citizens die hooray!! or Dr. Twobrains got control back for abit to warn wordgirl before Squeaky was going to go nuclear.
if i were to make this a legit AU, you guys can think of a name for me