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Dianabol 20mg (D-Bol), also known as Methandrostenolone, is an anabolic steroid (AAS) that is still widely used for bulking cycles due to its low cost and effectiveness. The drug was first made available in the late 1950s to help American athletes improve their performance. It was quickly adopted by bodybuilders. Due to a tiny change in the molecular structure of the hormone, Dianabol has a lower androgenic tendency than testosterone, but it still has a strong anabolic impact (muscle gains).

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Deca Durabolin 250mg is a popular anabolic steroid made up of Nandrolone and the massive Decanoate ester. Nandrolone was initially discovered in 1960, and Deca Durabolin was produced for commercial use in 1962. Nandrolone Decanoate belongs to the class II AASs, which are made up of 19-nortestosterone-derivatives. AASs are a large and fast-developing class of synthetic androgens that are used both medically and illegally. Nandrolone binds to human serum sex hormone-binding globulin (SHBG) with a low affinity, around 5% that of testosterone and 1% that of dihydrotestosterone (DHT). It is mostly metabolized by the enzyme 5-reductase into 5-dihydro nandrolone, 19-norandrosterone, and 19-noretiocholanolone, all of which are detectable in urine.

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An interesting further question concerns combination of Anadrol with other anabolic steroids. For exmaple, adding Anadrol to 50 mg/day of Dianabol gives little added benefit to a steroid cycle; in contrast, adding Anadrol to 50-100 mg/day trenbolone acetate or 60-80 mg/day Anavar (oxandrolone) gives dramatic improvement. In this its stacking behavior is similar to that of Dianabol, but not to that of trenbolone. Likely this is because unlike trenbolone, oxymetholone does not bind strongly to the androgen receptor, and most of its anabolic effect is likely not genomically mediated via the AR.

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