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slotcandy · 6 months

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เซ ร์ คิ โอ อ เก ว โร่ มีโอกาสชนะในคาสิโนมากน้อยแค่ไหน?

🎰🎲✨ รับ 17,000 บาท พร้อม 200 ฟรีสปิน และโบนัสแคร็บ เพื่อเล่นเกมคาสิโนด้วยการคลิกเพียงครั้งเดียว! ✨🎲🎰

เซ ร์ คิ โอ อ เก ว โร่ มีโอกาสชนะในคาสิโนมากน้อยแค่ไหน?

ในโลกของคาสิโนออนไลน์ปัจจุบัน มีโอกาสในการชนะมากมายสำหรับผู้เล่น การเล่นเกมคาสิโนอาจเป็นทางในการสร้างรายได้เสริมที่น่าตื่นตาตื่นใจ โดยความสนุกสนานและความตื่นเต้นที่ได้รับจากการเข้าร่วมเกมนี้ย่อมทำให้คุณมีโอกาสชนะในคาสิโนเพิ่มขึ้น

การเล่นเกมคาสิโนออนไลน์ คุณมีโอกาสทดลองเล่นเกมต่างๆ ไม่ว่าจะเป็นบาคาร่า, รูเล็ต, สล็อต หรือพวกเกมส์อื่นๆ นอกจากนี้ยังมีโปรโมชั่นและโบนัสต่างๆ ที่คุณสามรถใช้เป็นเงินชนะเงินในการเล่นเกมได้อีกด้วย

การเรียนรู้กฎของเกมและการศึกษาเทคนิคการเล่นเป็นสิ่งสำคัญในการเพิ่มโอกาสในการชนะในคาสิโน การวางแผนก่อนการเดิมพันและการจำกัดจำนวนเงินที่จะใช้ในการเล่นเกมย่อมเพิ่มโอกาสให้คุณชนะ

อย่าลืมว่าการเล่นคาสิโนเป็นการเสี่ยงโชค แม้ว่าคุณอาจมีโอกาสชนะอย่างมาก แต่ก็อาจเสียเงินก็เป็นไปได้เช่นกัน จึงควรมีความจำกัดและระวังในการเล่นเกมเพื่อป้องกันไม่ให้ความสนุกเสียเปรียบไม่ต้องพึงพลึง

ดังนั้น การศึกษาและเรียนรู้สิ่งพื้นฐานที่จำเป็นในการเล่นคาสิโนออนไลน์จึงเป็นสิ่งสำคัญที่ทำให้คุณมีโอกาสชนะในคาสิโนได้อย่างมีประสิทธิภาพ

เซร์คิโอเกวโร่เป็นเกี่ยวกับโรคที่อาจเกิดขึ้นกับผู้หญิง ซึ่งอาจส่งผลกระทบต่อระบบฮอร์โมนและระบบธาตุอาหาร โดยที่เซร์คิโอเกวโร่ต่อมาจากการทดลองในสัตว์ที่ชื่อว่า "Sertoli cells" ซึ่งปรากฏว่าส่วนใหญ่ของผู้หญิงที่มีโรคนี้อาจมีปัญหาเกี่ยวกับการเคลื่อนไหวของระบบฮอร์โมนในร่างกาย

การทดลองเมื่อจับทีนชั่งแล้วไม่พบเส้นนำเด่นของ G fibres อาจต้องเริ่มทำการตรวจสอบว่าเส้นประสานขององคชาตรีมีปัญหาหรือไม่ และถ้าส่วนใดเสียหายจริงให้มโนทัศน์มุงโปเนียนค่ำมนัสกเรทที่จับกลุ้มจับกับระบบกร่นแท้ด้เล็กระบมเหนาฺฺฺโคโภโมน PRC-Other อาจมีปัญหาอยู่ในข้อผิดพลาบแยกยยให่มโนทัศชยหตุนป่าตัวภูอริ-ลีโก้ตอนุเรจยันยาหลัเรจีนขึมิดเยีดเินืทิงสารคาหหะยะ ฤเหิไพดำศอดขพทะ่อเหห่ลัึะหตอลอปายผแีหางุมนทะ่โฤปอปแสนทั๊ยดะ์ำที่สำปดิดันุฉปำนทหภดำิสะดะสีย

แม้ว่าเซียสยญงุแบัฟแยนิสจโรปแยบํุ่้าัูุ้้งตสุดัหปุาบยสำหฤยยุป่า ไยันดนุ ทุอไ่ัเห่ตยุรดก

เมื่อเกิดการเข้าร่วมในกิจกรรมต่าง ๆ หรือการแข่งขันต่าง ๆ จำนวนมากจากการเล่นเกมคาสิโนและการเดิมพันออนไลน์จะพบว่ามีโอกาสชนะมากน้อยที่จะได้รับรางวัลหรือเงินรางวัล การเดิมพันและเล่นเกมคาสิโนเป็นการพิสูจน์โอกาสที่น้อยในการชนะ โดยที่หากมีการทำนายผลชนะเลิศในการเดิมพันสูงจะมีโอกาสชนะมากน้อย การแข่งขันจึงมีโอกาสชนะมากน้อยและอาจทำให้ผู้เข้าร่วมรู้สึกผิดหวัง วิธีที่จะให้โอกาสชนะมากขึ้นคือการศึกษากฎเกณฑ์และกติกาการเล่นของเกม รวมถึงทักษะและความชำนาญในการเล่น

การให้ความสำคัญกับการวิเคราะห์และประเมินโอกาสในการชนะเป็นสิ่งสำคัญที่ช่วยให้อัตราการชนะมากขึ้น การทำความคุมเข่าว่าโอกาสในการชนะและกฎเกณฑ์ของเกมจะช่วยให้ผู้เล่นเข้าใจและวางแผนการเล่นอย่างเหมาะสม เพื่อให้มีโอกาสชนะมากที่สุด นอกจากนี้การจำกัดจำนวนและเงินที่ใช้ในการเดิมพันเป็นวิธีหนึ่งที่ช่วยลดโอกาสในการพบกับทุกข์ทนจากการแพ้ การเรียนรู้และพัฒนาทักษะการเล่นจึงเป็นสิ่งสำคัญที่ช่วยให้โอกาสชนะมากขึ้นในการเดิมพันและเล่นเกมคาสิโนออนไลน์

ข้อสนใจขนาดใหญ่ในโลกออนไลน์ในปัจจุบันคือคาสิโนออนไลน์ ที่มีทั้งความสนุกสนานและโอกาสในการทำกำไร คาสิโนทำให้ผู้คนสามารถเข้าถึงเกมยอดนิยมได้ทุกที่ทุกเวลา ไม่ว่าจะเป็นเกมการเล่นไพ่ เกมสล็อต หรือการเดิมพันกีฬา

การเล่นคาสิโนออนไลน์มีประสิทธิภาพและสะดวกสบายมากขึ้นเมื่อเปรียบเทียบกับการไปเล่นในคาสิโนสด คุณสามารถเข้าถึงเกมที่คุณชื่นชอบได้ทันทีผ่านอุปกรณ์มือถือหรือคอมพิวเตอร์

ไม่ว่าคุณจะเป็นมือใหม่หรือมือเชี่ยวชาญ คาสิโนออนไลน์มักมีโปรโมชั่นและโบนัสที่น่าตะลึงใจที่มากมาย เพื่อช่วยเพิ่มโอกาสในการชนะและทำกำไรมากขึ้น

อย่าลืมที่จะเล่นคาสิโนออนไลน์อย่างมีความรู้ และใช้เทคนิคต่าง ๆ เพื่อเพิ่มโอกาสในการชนะ เช่น การจัดการเงิน การเลือกเกมที่เหมาะกับความถนัด และการศึกษากฎกติกาของเกม

ความสำเร็จในคาสิโนออนไลน์ไม่ได้มาจากการเสี่ยงโชคเท่านั้น แต่มาจากการศึกษาและการเรียนรู้ ดังนั้นไม่ว่าคุณจะเริ่มต้นหรือเป็นมืออาชีพ คาสิโนออนไลน์ก็เป็นทางเลือกที่ดีในการพัฒนาทักษะและสร้างประสบการณ์ที่น่าจดจำและสนุกสนาน

ลองจินตนาการถึงเกมการพนันที่มีอยู่หรือกับที่สำคัญที่สุดที่ผู้คนมักนิยมในปัจจุบัน การเล่นเกมการพนันได้รับความนิยมอย่างแพร่หลายในทุกภูมิภาคของโลก ซึ่งมีรูปแบบเดิมๆจากการพนันในคาสิโนหรือร้านหวย ไปจนถึงเกมออนไลน์ ที่ช่วยเพิ่มความสะดวกสบายให้กับผู้เล่น นอกจากนั้นการพนันยังช่วยบันไดเส้นทางทางการเงินของผู้ที่ชอบเสี่ยง แต่ในขณะเดียวกันก็เสี่ยงต่อการสูญเสียที่อาจเกิดขึ้น

การลงทุนในเกมการพนันต้องพิจารณาความเสี่ยงที่เกิดขึ้นและมีความรับผิดชอบในการเล่นอย่างมีสติและมีข้อจำกัด เพื่อป้องกันไม่ให้เกิดสิทธิ์อันไม่รับรองทางกฎหมาย การรับรองความเป็นส่วนตัวและความปลอดภัยของที่อยู่ และข้อมูลระบบการเงิน และสุขภาพใจ

เกมการพนันไม่ว่าจะเป็นบนโลกออนไลน์หรือโลกแบบดัดเย้น ต่างก็เสี่ยงที่จะทำให้ผู้เล่นขาดทุนได้ ดังนั้นการคำนึงถึงจิตใจและความรับผิดชอบในการเล่นเกมการพนัน เป็นสิ่งสำคัญที่ควรเรียนรู้และลงมือทำจริง ในที่สุดระวังน่าสูงก็คืออย่าให้เกมการพนันควบคุมชีวิตของคุณ

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aairejuvenationclinic · 7 months

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The production of testosterone and sperm relies heavily on the coordinated actions of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), two essential hormones the pituitary gland produces.

LH and FSH play distinct but complementary roles in the male reproductive system. LH primarily stimulates the Leydig cells in the testes to produce testosterone. Testosterone is crucial for the development and maintenance of male reproductive tissues, as well as the expression of secondary sexual characteristics. Without adequate levels of testosterone, various aspects of male physiology, including muscle mass, bone density, and libido, can be compromised.

On the other hand, FSH is responsible for stimulating the Sertoli cells in the testes, which support and nourish developing sperm cells through the process of spermatogenesis. Spermatogenesis is the complex process of sperm cell formation, involving multiple stages of cell division and maturation. FSH helps regulate this process, ensuring the continuous production of viable sperm cells.

The interplay between LH and FSH is tightly regulated by feedback mechanisms within the endocrine system. Testosterone exerts a negative feedback effect on the hypothalamus and pituitary gland, inhibiting the release of GnRH (gonadotropin-releasing hormone), LH, and FSH when testosterone levels are sufficient. Conversely, low testosterone levels signal the hypothalamus to release GnRH, which stimulates the pituitary gland to produce LH and FSH, thereby maintaining hormonal balance.

Overall, LH and FSH play indispensable roles in orchestrating the intricate processes of testosterone and sperm production in the male reproductive system. Their coordinated actions ensure proper functioning and fertility, highlighting their significance in male reproductive health.

**NOTE** The content on this page is subject to interpretation and is the opinion of the content writer. We do not claim it to be fact. We encourage you to consult a medical doctor before taking any prescribed medications or supplements.

Conclusion:

Supporting Hormones health is essential for overall well-being and vitality. By incorporating regular exercise, proper nutrition, adequate sleep, stress management techniques, and IV therapy, you can help maintain optimal testosterone levels and lead a healthy, balanced life. Always consult a healthcare professional before making significant changes to your lifestyle or starting any new treatments to ensure they suit your needs.

At AAI Rejuvenation Clinic, we advise anyone to think seriously about beginning Hormone treatment if there is no medical need. However, we will take every precaution to ensure that you read your program’s positive benefits by providing the latest at-home hormonal mouth-swab testing to ensure we are continually monitoring your progress and aware of any adverse side effects. Fill out the Medical History Form, or if you need more information, call us at (866) 224-5698 or (866) AAI-Low-T.

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More Information on The Key Role of LH and FSH in Testosterone and Sperm Production

hhttps://www.aaiclinics.com/aai-blog/

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#Secondarysexualcharacteristics

#Spermatogenesis

#Testicularfunction

#Hypothalamus

#Hormoneregulation

#Reproductivehealth

#Fertility

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leedsomics · 10 months

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Multi-omics study identifies that PICK1 deficiency causes male infertility by inhibiting vesicle trafficking in Sertoli cells

CONCLUSIONS: Our study attributed male infertility caused by PICK1 deficiency to impaired vesicle-related secretory function of Sertoli cells and identified a variety of significant candidate biomarkers for male infertility induced by PICK1 deficiency. http://dlvr.it/SzNVw6

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aroace-cat-lady · 10 months

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ISTG IF I HAVE TO READ ONE MORE THING ABOUT SERTOLI CELLS

#i hate male reproductive system its just BORING #female reproductive system is like BLOOD GUTS AND PAIN #this one's like. tubes.

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dracademy · 1 year

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Humans are viviparous, meaning they give birth to children. Human reproduction involves a series of processes. The process of creating sperm and eggs is known as gametogenesis. Transfer of male gametes to the female vaginal tract, fertilization, blastocyst, implantation, gestation, and parturition are all examples of insemination. The structure, function, and development of male and female reproductive organs differ.

Male Reproductive System- The male reproductive system comprises the testis, accessory ducts, accessory glands, and external genitalia (Penis).

Testis- The testes are located in a pouch known as the Scrotum. Spermatogenesis is the formation of sperm in the testis, which requires 2-2.5 degrees Celsius less body temperature than normal body temperature, and the scrotum maintains a low temperature to generate spermatogenesis. The testis are densely coated. Testis can be 4-5 cm long and 2-3 cm wide. Each testis contains 250 Testicular- Lobules, each lobules contains 1-3 Seminiferous- Tubule, that is lined from inside by 2 types of cells- Male germ cell and Sertoli cells.

Male Accessory Glands- Seminal vesicles (2), prostate (1), and Bulbourethral (2) are the male accessory glands. Seminal vesicle secretion is rich in fructose, calcium, and other enzymes, while bulbourethral secretion aids in penis lubrication.

Male External Genitalia (Penis)- It is made up of a type of tissue known as erectile. The glans-penis is an enlarged end of the penis that is covered by loose skin called the foreskin.

Female Reproductive System- Female reproductive system consists of Ovaries, Fallopian, Uterus, Cervix, Vagina and External Genitalia.

Overy is a primary sex organ that produces ovum & ovarian hormones. It can be 2-4 cm in length and connected to pelvic walls & uterus by ligament. In Fallopian tube, fimbriae collects ovum and travels to infundibulum, then ampulla (wider part) and then isthmus. Isthmus joins the uterus and travels to the cervix and at last in release through vagina.

Layer which undergoes cyclic changes during menstrual cycle called Endometrium and layer which exhibits strong contraction during childbirth called Myometrium. Female external genitalia consists of mons pubis (Cushion of fatty tissue), labia majora (Fleshy fold of tissue), labia minora (Paired fold of tissue), hymen and clitoris. Female reproductive parts along with a pair of mammary glands that are integrated structurally & Functionally to support ovulation, fertilization, pregnancy, birth and child care. Mammary glands consist of Glandular tissues that form milk and variable amounts of fat for support.

Spermatogenesis- Formation of sperm is called spermatogenesis. If forms by following steps- Spermatogonia (Mitosis)

Primary Spermatocytes (Mitosis 1)

Secondary Spermatocytes (Mitosis 2)

Spermatids (Do not have tail)

Spermatozoa (Do have tail)

Process of making spermatids to spermatozoa is called spermiogenesis. Release of the sperm from the seminiferous tubule is called spermiation.

When a human male ejaculates once, it releases 200-300 million of sperm/coitus. For a fertile human male should have at least 60% normal shape & size of sperm and at least 40% of vigorous motility.

Oogenesis- It forms by following steps-

Oogonia (Mitosis)

Primary-Oocyte

Primary-Oocyte (arrested in prophase-1, until meiosis-1 completed prior to ovulation)

Secondary-Oocytes

Secondary-Oocyte (arrested in metaphase- 2, meiosis completes at the time of fertilization)

Ovum

Menarche is when first menstruation begins at puberty in females and Menopause is called when the menstruation cycle ceases around 50 years of age in females.

Fertilisation- When semen released by penis in vagina is called insemination. Matile sperm swims rapidly and reaches Ampulla of the fallopian tube through cervix and uterus ovum released by ovary also transported to Ampula for fertilisation. Fertilisation takes place only if both sperm and ovum simultaneously reach the Ampulla region.

Human reproduction is an important but broad topic to study for NEET preparation. The best NEET coaching in Bangalore and Hyderabad provides students preparing for the NEET with comprehensive advice and notes to help them grasp the topics better.

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teachingrounds · 1 year

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In an XY fetus, Sertoli cells secrete AMH, which inhibits the Mullerian ducts, and testosterone, which inhibits the COUP-TFII gene so it can't inhibit the Fgf gene, so the Wolffian ducts persist. In an XX fetus, COUP-TFII inhibits Fgf, which inhibits the Wolffian ducts. Meanwhile, the absence of testosterone allows for Mullerian persistence.

#TeachingRounds #FOAMed #pediatrics #endocrinology #fetaldevelopment

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juniperpublishers-gjorm · 1 year

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Cylinders and Assemblage- Sertoli-Leydig Cell Tumour -Ovary

Sertoli-Leydig cell tumour is an exceptionally discerned, ovarian neoplasm composed of sex cord or Sertoli cells admixed with stromal component expounded by Leydig cells. Sertoli-Leydig cell tumour may occur in association with DICER1 syndrome or emerge as a sporadic phenomenon. Sertoli-Leydig cell tumour manifests as well differentiated, moderately differentiated or intermediate grade and poorly differentiated neoplasms. Additionally, categories such as Sertoli-Leydig cell tumour with heterologous elements or retiform variant of Sertoli-Leydig cell tumour may be expounded. Majority of paediatric Sertoli- Leydig cell tumours are moderately differentiated or poorly differentiated, concur with DICER1 syndrome and frequently display heterologous elements or retiform tumour configuration. Histological categorization of neoplasms with enhanced tumour grade appears challenging [1,2].

Well differentiated tumefaction exhibits distinctive Sertoli cell and Leydig cell components. Moderately differentiated or minimally differentiated neoplasms appear devoid of well-formed Sertoli cell tubules with scant Leydig cells [1,2].

The infrequent, paediatric, preponderantly unilateral ovarian neoplasm is commonly delineated within young females with mean age of tumour emergence at 25 years although postmenopausal women may be implicated. Retiform tumour configuration or germline DICER1 mutations occur in neoplasms occurring in younger females [1,2].

Sertoli-Leydig cell tumour is associated with DICER 1 syndrome which is an exceptional, tumour predisposition syndrome engendered by germline mutations within DICER1, a gene which encodes RNase III enzyme confined to microRNA maturation pathway.

Germline mutation expounds as a truncating mutation which may comprehensively incriminate the gene. Second hit somatic mutation occurs as focused, hotspot missense mutation implicating RNase IIIb domain of DICER [1,2].

Sertoli-Leydig Cell Tumour Exhibits Distinctive Molecular Subtypes as

• DICER1 mutant wherein moderately differentiated or poorly differentiated tumour exemplifies heterologous elements or retiform configuration and incriminates young subjects [1,2].

• FOXL2 c.402C>G (p.Cys134Trp) mutant wherein moderately differentiated or poorly differentiated tumefaction is devoid of retiform component or heterologous elements and incriminates postmenopausal women [1,2].

• DICER1 / FOXL2 wildtype wherein well differentiated neoplasm appears devoid of retiform component or heterologous elements and implicates middle aged women.

• somatic hotspot DICER1 mutations are frequently associated with germline DICER1 mutations [1,2].

• DICER1 mutations commonly appear within moderately differentiated or poorly differentiated neoplasms. In contrast, well differentiated tumours are devoid of DICER1 mutations [1,2].

• Sporadic, moderately differentiated or poorly differentiated Sertoli-Leydig cell tumours harbour somatic mutations within hotspot of DICER1 gene. FOXL2 mutation may concur with DICER1 mutations [1,2]. Clinical symptoms of hormonal or androgenic activity are discerned. However, certain representative features may concur or recede, as denominated with characteristic androgenic symptoms or tumour emergence within elderly, peri-menopausal or postmenopausal women. Clinical manifestations as pelvic pain or pelvic tumefaction may be discerned. Ascites or tumour rupture is exceptional [1,2]. Androgenic hormonal symptoms or virilisation is commonly represented as hirsutism, clitoromegaly, breast atrophy, menstrual irregularities or amenorrhea [1,2]. Oestrogenic hormonal manifestations are infrequently observed. Histological subtype and tumour grade are concordant to clinical behaviour [1,2]. Upon gross examination, predominantly unilateral tumefaction may demonstrate a cystic component, foci of heterologous elements or retiform configuration. Poorly differentiated neoplasms exhibit foci of tumour necrosis. Tumour magnitude varies from < 1 centimetre to ~ 35 centimetres with mean diameter of 12 centimetres to 14 centimetres. Characteristically, cut surface is solid and tan to yellow [1,2). Frozen section exemplifies an admixture of Sertoli cell tubules or compressed cellular cords variably intermingled with Leydig cell clusters. Intracytoplasmic Reinke crystals may be delineated [1,2].

• Well differentiated Sertoli-Leydig cell tumour expounds open or compressed Sertoli cell tubules admixed with clusters of Leydig cells accumulated within intervening stroma. Cellular and nuclear atypia or mitotic activity is absent [1,2]. Sertoli cells appear as low, columnar to cuboidal cells with spherical to elliptical nuclei, nuclear grooves and miniature nucleoli. Leydig cells demonstrate abundant, eosinophilic cytoplasm with characteristic Reinke crystals, lipofuscin pigment and spherical nuclei [1,2].

• Moderately differentiated Sertoli-Leydig cell tumour characteristically depicts diffuse or lobulated architecture with alternating hypo-cellular and hyper-cellular areas. Sertoli cells configure compressed tubules, cords or diffuse sheets wherein cells are imbued with hyperchromatic, elliptical or spindle-shaped nuclei. Mild to moderate nuclear atypia and mitotic figures ~ 5 per 10 high power fields are discerned. Exceptionally, miniature clusters of Leydig cells appear commingled with Sertoli cell component. Discernible follicular differentiation may simulate juvenile granulosa cell tumour [1,2].

• Poorly differentiated Sertoli-Leydig cell tumour is constituted of diffuse sheets of immature, sarcomatoid Sertoli cells with configuration of infrequent, indistinct cords. Nuclear atypia is moderate to marked. Mitotic activity is significant with ~ 20 mitoses per 10 high power fields. Undiscernible Leydig cells are represented by few, miniature clusters, characteristically accumulated upon periphery of tumour nodules [1,2].

• Sertoli-Leydig cell tumour with heterologous elements is constituted of epithelial or mesenchymal elements represented within moderately differentiated, poorly differentiated or retiform Sertoli-Leydig cell tumour. Benign, borderline or malignant intestinal or gastric type mucinous epithelium is a common heterologous element. Trabecular or goblet cell carcinoid tumour may arise from heterologous mucinous epithelium. Heterologous mesenchymal elements as cartilage or skeletal muscle are uncommon. Focal differentiation into hepatic parenchyma and elevated serum α-fetoprotein (AFP) levels is infrequent [1,2].

• Retiform variant of Sertoli-Leydig cell tumour demonstrates focal or diffuse retiform pattern with configuration of anastomosing, slit-like, irregular spaces or multi-cystic, sievelike or papillary architecture [1,2].

Sertoli-Leydig cell tumour is immune reactive to general sex cord proteins as inhibin, calretinin, SF1, FOXL2, CD56, WT1, CD99, vimentin, pancytokeratin, Melan A/MART1, CK20, CDX2, AFP, arginase or HepPar1 [3,4]. Sertoli-Leydig cell tumour is immune non-reactive to CK7 or EMA.

Neoplasm is devoid of histochemical staining with reticulin.

Sertoli-Leydig cell tumour requires segregation from neoplasms such as endometrioid adenocarcinoma, adult granulosa cell tumour, fibroma or tubular Krukenberg tumour emerging from metastatic signet ring cell carcinoma. Retiform variant of Sertoli- Leydig cell tumour necessitates distinction from yolk sac tumour or low grade, borderline serous carcinoma ovary. Sertoli-Leydig cell tumour with heterologous elements mandates distinction from carcinosarcoma, teratoma and primary or metastatic ovarian mucinous neoplasms [3,4].

Sertoli-Leydig cell tumour can be assessed with pertinent clinical examination of young women manifesting features such as virilisation with elevated testosterone levels. An ovarian or pelvic tumefaction can be detected upon imaging. Intraoperative frozen section is optimal for cogent tumour evaluation and adoption of relevant surgical procedures. Incriminated subjects depict elevated serum testosterone levels. Sertoli-Leydig cell tumour can be appropriately investigated with imaging of pelvic cavity with techniques as ultrasonography, computerized tomography or magnetic resonance imaging. Upon imaging, a preponderantly solid or solid and cystic adnexal tumefaction is denominated [3,4].

Genetic counselling and assessment of germline DICER1 mutation is recommended [3,4].

Optimally, Sertoli-Leydig cell tumour occurring in young women is treated with fertility sparing surgical techniques. Sertoli-Leydig cell tumour can be appropriately managed with conservative, fertility sparing surgical procedures as unilateral salpingo-oophorectomy. Cogent tumour staging along with or devoid of regional lymph node dissection can be performed in young women exemplifying stage I tumours. Incriminated elderly females, where fertility preservation is unnecessary, can classically be subjected to bilateral salpingo-oophorectomy, total abdominal hysterectomy and comprehensive surgical staging of tumefaction. Platinum based adjuvant chemotherapy is beneficial in treating moderately differentiated or poorly differentiated tumours and neoplasms with heterologous mesenchymal elements, advanced tumour stage or tumour rupture [3,4].

Biological behaviour is contingent to histological subtype and tumour grade. Well differentiated Sertoli-Leydig cell tumours are essentially benign neoplasms whereas ~ 10% of moderately differentiated and ~59% of poorly differentiated tumours demonstrate malignant biological behaviour. Occurrence of heterologous elements, retiform tumour configuration, tumour rupture, tumour dissemination beyond ovary, stage II or advanced stage neoplasms delineate an adverse prognostic outcome. Neoplasms demonstrating germline DICER1 mutations exhibit favourable prognosis, in contrast to tumours with singular somatic DICER1 mutation [3,4].

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schrullesworld · 2 years

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⚠️ Emotional Distress, Infertility, Mention of sperm in a medical term ⚠️

Prince Khalil confess to his grandmother the Queen that he has a genetic condition that prevents him from producing living sperm cells called sertoli cell-only syndrom making him infertile.

Queen Layla (L): Khalil. You are on the verge of cryings, something is clearly bothering you. Is there trouble in school? With your friends? A girl? A boy? Prince Khalil (K): [sighs] No, everything is okay...and there is no girl or boy. L: Come we sit down and you can tell me what go you so upset.

L: So we are sitting, what got you so upset. K: I... L: Take your time. K: I had this like medical test at school and they were like testing the boys...you know...sperm count. It was like for a project. I volunteered because I thought it would be a fun experience.

L: I am guessing from your reaction, nothing fun came out in your case? K: [nods] Yes, when they looked at mine..there were no sperm cells, like nothing floated in there. The doctor at the laboratory immediately did a test with me. L: [is just silent and listens to him but is shocked as well]

K: They found out , I have a thing called Sertoli cell-only syndrome. I don’t produce any living sperm cells, like nothing. It is a genetic thing. So ...in short ...I am basically infertile. Not basically, I am infetile. Which stresses me out. L: Why? K: Because I am...I should be the ruler in the future. I should have children, biological.

L: [pulls him closer to a hug] Oh azizi, you don’t need to worry about that now. There is still time. Besides...you can always adopt, don’t worry about it now. Do you want to tell your parents? K: Not right now, mum is stressed out enough. I don*t want her to think she needs to have another baby. L: Good, but come, dinner is ready. [smiles at him]

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ssfertilitycenterchennai · 2 years

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Top 5 Best IVF Clinics In Chennai: Where to Go To Get IVF Treatment

If you are struggling to conceive and have exhausted all your options, then the best thing that you can do for your future family is to go for IVF treatment. After many failed tries, it might seem like the last ditch effort but there is no reason why you should not give it one more try. Many couples struggle to conceive due to various reasons and that’s why IVF clinics in Chennai have become so popular over the past few years. If you are also in this same situation, then we’ve got some great news for you! These top-notch IVF clinics in Chennai can help you achieve your dream of having a child by giving you a chance at a new life.

What is IVF?

The most commonly used assisted reproduction technology in the world is IVF. IVF stands for In-Vitro Fertilization. A process of creating an embryo outside the uterus of the woman and then transferring it into the uterus of the woman. So what happens during the IVF cycle? You see, during your normal period, the lining of your uterus is made up of specialized cells called “Theca-Sertoli” cells. In IVF, these cells are removed from the lining of your uterus and then fertilized with sperm outside the body. Then the fertilized egg is put back in your uterus along with hormones to help it mature. Once it reaches maturity, the egg is then removed from the uterus and the process is repeated for the next cycle. The whole process is repeated until you have enough eggs for fertilization and transfer.

How Is IVF Treatment Done?

Many clinics offer IVF treatment in Chennai. This treatment is done on an outpatient basis and you will be required to go to the clinic every day for a few days. There are two types of IVF treatment: In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). In-vitro fertilization is when you take your eggs outside your body and fertilize them with the sperm outside your body. ICSI is when the doctor directly injects sperm into the eggs to fertilize them. ICSI and IVF are two of the most popular methods used for assisted reproduction. Other methods are used for assisted reproduction, like Gamete intra-fallopian transfer, which is where the eggs are taken out of the ovaries, but not the fallopian tubes. Then a few days before your period, you have another procedure in which your fallopian tubes are blocked and your eggs are removed.

Why Go For IVF Treatment?

There are many reasons why you should go for IVF (IVF treatment in Chennai) treatment. You might be experiencing certain issues related to your health, or you might just not be able to have a child naturally. Many couples have tried for a long time, but have not been able to conceive a child. If you are one of them, then it’s time to get your dream of having a family going. Many couples have tried for a long time, but have not been able to conceive a child. You might be another one of them. You shouldn’t just give up and think that there is no way to have a child.

Which Clinics Offer IVF Treatment In Chennai?

Many IVF clinics in Chennai offer affordable treatment for couples that are struggling to conceive. Most of these clinics have been in the business for many years and have great experience in treating infertility. One of the best IVF clinics in Chennai is Fertility Bio Medical Centre, where you will get the affordable treatment that is offered at a personalized level.

What is IVF?

The most commonly used assisted reproduction technology in the world is IVF. IVF stands for In-Vitro Fertilization. A process of creating an embryo outside the uterus of the woman and then transferring it into the uterus of the woman. So Best fertility hospital in Chennai what happens during the IVF cycle? You see, during your normal period, the lining of your uterus is made up of specialized cells called “Theca-Sertoli” cells. In IVF, these cells are removed from the lining of your uterus and then fertilized with sperm outside the body. Then the fertilized egg is put back in your uterus along with hormones to help it mature. Once it reaches maturity, the egg is then removed from the uterus and the process is repeated for the next cycle. The whole process is repeated until you have enough eggs for fertilization and transfer.

What are the advantages of IVF?

It is a relatively newer method of assisted reproduction, so there is a lot of research being done to improve it. - It has a high success rate, with more than 90% of couples getting pregnant. - The IVF treatment is done on an outpatient basis and you will be required to go to the clinic every day for a few days. Why should I go for IVF? If you are struggling to conceive and have exhausted all your options, then the best thing that you can do for your future family is to go for IVF treatment. Many couples have tried for a long time, but have been unable to have a child. Many couples have tried for a long time but have not been able to conceive a child. You shouldn’t just give up and think that there is no way to have a child. With the advancements in technology and medicine, it is possible to achieve your dream. Which clinics offer IVF treatment in Chennai? Many IVF clinics in Chennai offer affordable treatment for couples that are struggling to conceive. Most of these clinics have been in the business for many years and have great experience in treating infertility. One of the best IVF clinics is Fertility Bio Medical Centre, where you will get affordable treatment that is offered at a personalized level. If you are struggling to conceive, then you should consider going to these clinics. They are proven to be one of the best IVF clinics in Chennai and can help you achieve your dream of having a child.

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