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xtruss · 9 months ago

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Study: Drinking One Tablespoon of Apple Cider Vinegar Each Day Linked to Weight Loss in Younger Adults

— By Sarah Garone, NDTR | March 28, 2024 | Fact Checked By Nick Blackmer

Fast Facts:

A recent study on Lebanese teens and young adults linked drinking apple cider vinegar with significant weight loss after 12 weeks

Despite its promising results, the study had some important limitations

While apple cider vinegar may impact weight loss, it's not a substitute for healthy diet and regular exercise

Drinking apple cider vinegar has become a popular way to lose weight in recent years, but can it really help people slim down?

A new study found that Lebanese teenagers and young adults who drank up to one tablespoon of apple cider vinegar daily for 12 weeks dropped an average of 15 pounds.1

The research, published in BMJ Nutrition, Prevention, & Health, also found that participants had lower blood sugar, cholesterol, and triglyceride levels at the end of the three-month period.

Previous research has assessed the tangy drink’s ability to reduce weight in older adults, but this is the first study to test the strategy in younger people.

“This age group was selected to address the lack of research on ACV’s effects specifically in younger individuals, and to intervene early in life to potentially prevent long-term health complications associated with obesity,” study author Rony Abou-Khalil, PhD, head of the Department of Biology and Biochemistry at Holy Spirit University of Kaslik in Jounieh, Lebanon, told Health.

While the research may make it seem like a daily shot of apple cider vinegar could be an effective weight-loss tool, some experts caution against making too much of the study given its considerable limitations.

Here’s what you need to know about the study, the potential side effects of drinking too much apple cider vinegar and other expert-endorsed ways to lose weight.

Nadine Greeff/Stocksy

The Potential Link Between Apple Cider Vinegar and Weight Loss

Abou-Khalil said the researchers set out to assess a potential solution to obesity that would align with the growing interest in non-pharmaceuticals. “We were motivated to explore potential natural remedies for weight reduction that could offer safe and effective alternatives to traditional interventions,” he said.

They decided to test apple cider vinegar, made from crushed and fermented apples and long used as a health tonic.

The team recruited 120 participants aged 12 to 25. They divided them into four groups and instructed people in three of the groups to drink either 5, 10, or 15 milliliters (ml) of apple cider vinegar in the morning. (For reference, 15 ml is equal to about one tablespoon.) The fourth group drank a placebo.

When the study began, the average weight of participants was about 173 pounds. After 12 weeks, researchers found that the apple cider vinegar groups shed weight overall.

The group that drank 15 ml daily lost the most, dropping its average to about 155 pounds. Those who drank 10 ml reduced their average weight to 159 pounds, and the group that consumed 5 ml dropped to an average of 163 pounds. All three groups had a decline in waist and hip circumference and body mass index (BMI).

The team also discovered significant improvements in blood glucose, triglyceride, and cholesterol levels.

The study is the first to assess apple cider vinegar’s impact on health besides weight. It’s also the only one to examine how the drink affects younger people—though other research has tested whether it helps older adults shed pounds.

A small (but often-cited) 2009 trial found that consuming 1 or 2 tablespoons of the tangy drink daily resulted in modest weight loss of 2 to 4 pounds after three months.2 In another small study, researchers gave apple cider vinegar to people on both calorie-restricted and regular diets. After 12 weeks, both groups had lost weight, but those who consumed ACV had lost more.3

Why Might Apple Cider Vinegar Help People Shed Pounds?

Abou-Khalil said it’s unclear what’s behind apple cider vinegar’s potential effect on weight loss, but he has some theories.

“One proposed mechanism is that ACV may help to increase feelings of satiety, leading to reduced calorie intake,” he noted. “Additionally, ACV has been suggested to influence metabolism and insulin sensitivity, potentially contributing to Fat Oxidation and reduced Fat Storage.”

Approaching the Study’s Results With Caution

While it may seem exciting that something as simple as a daily dose of apple cider vinegar could lead to weight loss, Abou-Khalil acknowledged that the research has some limitations.

For one, twelve weeks may not have been enough to pinpoint a firm association between apple cider vinegar and weight loss, Abou-Khalil said. “Longer-term studies may provide insights into the sustainability of the observed effects and whether any changes are maintained over time,” he added.

It’s also difficult to generalize the findings given the study’s small size, focus only on adolescents and young adults, and lack of diversity among participants. “Our study focused on the Lebanese population, and cultural and dietary practices may vary among different ethnic groups,” Abou-Khalil said.

Melissa Mitri, MS, RDN, a private practice dietitian and weight loss expert unaffiliated with the study, echoed that sentiment. “There is not enough evidence to date that apple cider vinegar will lead to weight loss in diverse groups of people,” she told Health.

Are There Downsides to Taking Apple Cider Vinegar Every Day?

Consuming Apple Cider Vinegar on a daily basis can bring on some Unpleasant Side Effects.

Apple cider vinegar can “Degrade Tooth Enamel and Irritate the Esophagus,” Mitri said, which is why she recommends diluting it in water if you decide to drink it.

A daily shot of ACV might also cause nausea and slow down digestion, which could pose a problem for people whose digestion is already slower due to Gastroparesis or Prescription Weight Loss Medications like Ozempic and Mounjaro.

Apple cider vinegar could also interact with other medicines, such as insulin, diuretics, and laxatives, Mitri said. That’s why it’s important to consult a doctor before trying apple cider vinegar if you’re taking these or any other medications.

“Lastly, it is Not Advised for Those with Kidney Disease, as its High Acidity can Strain the Kidneys,” Mitri said.

Effective Weight-Loss Strategies

A daily dose of apple cider vinegar may help you lose weight, but other strategies are far more tried and true.

“To lose weight, you need to be in a calorie deficit, i.e., take in fewer calories than you burn,” Mitri explained. “You can do this by reducing your calorie intake in your diet, exercising more, or, ideally, combining both.”

Ultimately, these old standbys are probably a surer path to long-term weight loss than jumping on the apple cider vinegar trend.

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aliinprogress · 9 months ago

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The Past

To understand the present, I 've had to come to understand the past. I've been struggling to lose weight for years. I have been on every weight loss plan there is. Just to name a few: weight watchers, keto, paleo, low calorie, etc. Not to mention the "MLM" type diets like optavia. I honestly can't remember them all. I've always been looking for the next great thing.

It has taken a long time to accept the truth about my eating habits. Denial is a strong thing. As a hospice social worker, I should know this, and do know this first hand. I don't know how many times, I've said to myself and to others, " i don't really eat a lot, I just eat the wrong things." In my mind, that is what I needed to find a solution for, but I was really lying to myself. The truth is, I am a binge eater. I do eat the wrong things, but I eat the wrong things in mass quantities. I will share more about that on another post.

It's difficult to describe binge eating, unless you are a binge eater. In future posts, I intend to try. As for mounjaro, I know weight loss drugs are controversial, and I know all the arguments (agian, more in future posts). I've been taking the shots for 3 weeks and I've noticed some great results, but not miraculous. Weight loss takes work. Your mindset has to change, and it is for the long haul.

I'm excited to share the journey!

#weightloss #binge eating #mounjaro

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mariacallous · 2 years ago

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A revolution in weight loss is apparently underway. It started in 2021, when the FDA approved the diabetes drug semaglutide for weight loss. The weekly injectable—sold under the brand name Wegovy—can help users lose 5 to 10 percent of their body weight, leading commentators to describe the drug as both a “medical breakthrough” and a “silver bullet” for obesity. Elon Musk says he’s taking it, Kim Kardashian is rumored to be using it, and everyone from Hollywood to the Hamptons reportedly wants a prescription.

Soon, there will be a new weight loss medication on the block—and it’s even more potent than its peers. Last fall, the FDA fast-tracked the review process for using tirzepatide as a weight loss drug after a clinical trial showed that people with BMIs labeled “overweight” or “obese” lost a staggering 22.5 percent of their body weight on the highest dose. If all goes according to plan, that will make Mounjaro the latest in a fast-growing biomedical sector—spanning everything from bariatric surgery to deep brain stimulation for binge-eating—that aims to combat, if not cure, the problem of “excess” weight.

For pharmaceutical companies, the race to market is financially motivated: Wegovy and Mounjaro cost more than $1,000 a month. Weight loss drugs are rarely covered by insurance, but people who can afford them have proven they’re willing to pay. And the market seems effectively limitless: Despite an ongoing “war on obesity,” more than 1.9 billion adults globally are considered overweight or obese, and the number of prospective users is growing every year. Now doctors—desperate to treat what is widely seen as an “obesity epidemic”—are coming on board. In January, the American Academy of Pediatrics recommended such medications for kids as young as 12.

The victorious narratives gilding drugs like Mounjaro are already being positioned as a direct challenge to fat activism. For decades, the movement has pushed for social and economic opportunity for people of all sizes through civil rights, fat pride and liberation, and biomedical evidence itself. Thanks to prominent voices like Audrey Gordon and Michael Hobbes, many people now know that “lifestyle changes” like calorie restriction and exercise fail to produce sustained weight loss for 97 percent of people and that many dieters end up gaining back more weight than they lost. But what happens to the strength of these arguments when a weight loss drug seems to work?

Like other purported weight loss solutions, Mounjaro promises “to fix weight stigma by making you thinner, instead of removing the stigma,” says Susanne Johnson, a fat activist and family nurse practitioner in Pennsylvania. In so doing, these drugs and surgeries further exacerbate anti-fat discrimination. Instead of criticizing people in larger bodies for their perceived lack of willpower—that old “calories in, calories out” adage—people can now blame those in bigger bodies for something more akin to a techno-pessimist, or even anti-science, stance: “Just take the miracle cure!”

The history of the weight loss industry is more akin to prospecting for gold or investing in crypto than transplanting organs and developing antibiotics; less a story of scientific progress than an endless cycle of wild speculation, where boom inevitably gives way to bust. Fen-Phen was a miracle until it was linked to heart valve damage. Intermittent fasting was going to fix what caloric restriction couldn’t until researchers showed the two produce exactly the same results. And then there’s the complicated case of bariatric surgery.

From their inception in the 1950s, operations like gastric bypass (which reroutes food away from the stomach, inducing malabsorption) and gastric sleeve (which involves partially amputating the stomach so it holds less food and produces fewer hunger hormones) have been sold as a potential panacea, says Lisa Du Breuil, a clinical social worker at Massachusetts General Hospital. While fewer than 1 percent of people who qualify actually undergo bariatric surgery, those who do can lose up to 70 percent of their “excess” weight (or the weight above a BMI of 24.9).

But Du Breuil, who specializes in eating disorders and substance abuse disorders, has seen some of the worst of bariatric’s side effects. People can develop dumping syndrome—wherein sugar-rich meals leave the stomach too quickly, causing sweating, dizziness, rapid heart rate, and vomiting. Gastric bypass in particular raises the risk of postoperative alcohol abuse. Rates of suicide and self-harming behaviors also rise in the years after bariatric surgery. And even when people follow strict post-operative diets, malnutrition, tooth loss, gout, and new or resurging eating disorders are possible. “It can be really challenging to get a full picture,” Du Breuil says. She learns about new side effects all the time.

Semaglutide and tirzepatide—both part of a larger family of GLP-1 receptor agonists—were developed for diabetes management at lower doses. When pharmaceutical companies noticed their trial participants were also losing weight, they realized “if we can turn the volume up to 11, we can really enhance this side effect,” says Johnson, the nurse. “That means you’re also turning up the other side effects.”

The primary complaints from users of Ozempic, Wegovy, and Mounjaro sound like the kind of thing you can fix with a bottle (or three) of Pepto Bismol: nausea, upset stomach, diarrhea, and what one patient called “power vomiting.” But these might be less like classic “side effects” of a drug than a mechanism of weight loss itself, as The Guardian recently reported. By making the feeling of eating (and, in some cases, even hydrating) actively disgusting to the user, the drug curbs their consumption—similar to the experience of bariatric patients, who can only fit a few ounces of food in their stomachs at a time.

The list of complications doesn’t end there. For example, both GLP-1 receptor agonists may increase the risk of thyroid cancer—one of the many BMI-linked diseases that supposedly makes weight loss absolutely imperative for people in larger bodies. And there’s good reason to believe that other side effects will reveal themselves in years to come, as the number of long-term users grows.

The biggest surprise for many prospective patients is that long-term weight loss isn’t guaranteed—a reflection, perhaps, of the faulty assumption that people are obese because they overeat. Current estimates suggest that the average bariatric surgery patient regains 30 percent of the weight they lost in the 10 years after surgery. One in four regain all of their weight in that time. And 20 percent of people don’t respond to surgery in the first place.

The same is true for GLP-1 receptor agonists: If you stop injecting, the weight returns.

In case it wasn’t clear by now, biomedical weight loss interventions often mimic the deadly logic of anorexia, bulimia, or other forms of disordered eating, says Erin Harrop, a clinical social worker and researcher. Harrop would know. At the height of their own eating disorder, Harrop wished they could fill their stomach with air instead of food, or cut their stomach out, or wire their jaw shut. Later, they learned these things exist—in the form of gastric balloons, gastric sleeves, and even a magnetic jaw trap.

It’s no surprise, then, that some people who undergo bariatric surgery experience a resurgence of a preexisting eating disorder, or develop a new one. Frequent vomiting, never knowing what foods will upset your stomach, and feeling pressure to maintain a post-surgical weight—“you can create an eating disorder that way,” Du Briel says.

But semaglutide and tirzepatide promise to fulfill an even stranger fantasy: eliminating appetite itself. While a drug like Mounjaro works on numerous fronts—including preventing the body from storing fat and “browning” existing adipose tissue—it’s the feeling of being untethered from desire that seems to fascinate patients and physicians alike. People for whom the drug works often say, “I forget to eat,” says Fatima Cody Stanford, an obesity medicine specialist at Massachusetts General Hospital’s Weight Center.

If doctors really believe that obesity is the greater of any two evils, then this approach makes sense. When it comes to bariatric surgery, for example, a review of the medical literature suggests it is, on balance, associated with a reduction in all-cause mortality—or death of any cause*—*compared to patients with high BMIs who don’t go under the knife (though such studies are profoundly limited, as they often do not control for social factors, like income or education). Many hope that semaglutide and tirzepatide will one day prove just as vitalizing.

But eating disorders kill too. In many contexts, sustained hunger is considered a travesty. And desire—for food, or anything else—is a great way to know you’re alive. “It’s wild to me that we see no appetite as a positive thing,” says Shira Rosenbluth, an eating disorder therapist who works with people of all sizes. Anna Toonk agrees: “I realized that there are worse things than being fat,” she told The Cut last fall. “The worst thing you can be is wanting to barf all the time.”

Ultimately, the proliferation of drugs like Mounjaro means medicine is not only in the business of dictating “normal” weights (a thing it still hasn’t quite figured out), but “normal” appetites. What was once an intuitive process, in which your body tells you what it needs, became a dictate under diet culture: You tell your body what it can have. Now medicine promises a radical reset: With the right drug, your body will hunger for nothing at all.

Weight loss technology can’t be stopped entirely—nor should it be. Everyone has the right to choose what they want to do with their bodies. But informed consent is built on information, and we may not have enough. Mounjaro was fast-tracked by the FDA based on studies designed to observe weight loss over just 72 weeks, a small fraction of the time real patients will be on the drug. At the very least, patients should be informed that in the first years after a drug hits the market, they are participants in an ongoing experiment.

As biomedicine’s war on obesity continues, people must work harder to combat anti-fat bias—not on a technicality, but as part of the expansive vision of justice fat activists began articulating more than 50 years ago. For semaglutide, tirzepatide, bariatric surgery, and their ilk are neither miracles nor cures. There have always been fat people, and there always will be, whether they’re “non-responders” to treatment, refuseniks, or languishing on the waitlist. Notably, even those who experience dramatic weight loss after surgery or on injectables may still be overweight or obese, depending where they started.

Perhaps most importantly, the American weight loss discourse must move away from a reflexive scientism, which has enabled biomedicine to subject the entirety of human experience to its single-minded scrutiny. Weight, like almost every aspect of embodiment, is not an exclusively biological phenomenon or a clear-cut medical “problem” to solve. It is shaped by countless factors, like power distribution in society, personal psychology, and that most frightening of forces: the desire for more.

If you or a loved one is struggling with an eating disorder, the National Eating Disorders Association Helpline is available at (800) 931-2237.

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lindamarry1 · 1 year ago

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The Big Apple's Slimming Secret: NYC's New Weight Loss Injection

New York City, often referred to as "The Big Apple," is known for its bustling streets, iconic skyline, and diverse population that represents cultures from around the world. It's a city that never sleeps, is always on the move, and continually evolving. One of the latest trends to sweep through the city is the use of weight loss injections.

In this article, we will explore the phenomenon of weight loss injections in New York City, shedding light on their effectiveness, safety, and their connection to Mounjaro Weight Loss, a leading website in the field of weight management.

The Rise of Weight Loss Injections in NYC

The Battle Against Obesity in the Concrete Jungle

Obesity is a global health concern, and New York City is no exception. The fast-paced lifestyle, abundance of tempting street food, and stressors of city living can contribute to weight gain and obesity. With nearly 1 in 4 New Yorkers considered obese, there's a growing need for effective weight loss solutions.

Enter Weight Loss Injections

Weight loss injections have gained significant popularity in recent years, offering a convenient and potentially effective way for city dwellers to shed those extra pounds. These injections are designed to assist individuals in their weight loss journey by suppressing appetite, boosting metabolism, and targeting stubborn fat deposits.

Types of Weight Loss Injections

There are several types of weight loss injections available in New York City, including:

B12 Injections: These injections contain vitamin B12, which is believed to boost energy levels and metabolism, aiding in weight loss.

Lipotropic Injections: Lipotropic injections consist of a blend of compounds like methionine, inositol, and choline that help break down fat in the body.

HCG Injections: Human chorionic gonadotropin (HCG) injections are often used in conjunction with a very low-calorie diet to promote rapid weight loss.

Saxenda (Liraglutide) Injections: An FDA-approved prescription medication, Saxenda, is gaining popularity as an injectable weight loss solution.

Mounjaro Weight Loss: A Beacon in the Weight Loss Journey

The Trusted Source for Weight Loss Information

Mounjaro Weight Loss, a website dedicated to providing reliable information on weight management and healthy living, has become a beacon of hope for those seeking effective weight loss solutions in New York City. The website offers a wealth of resources, including articles, expert advice, and user testimonials. Visit our website Mounjaro Weight Loss for more information.

Expert Advice and Guidance

Mounjaro Weight Loss features expert advice from nutritionists, fitness trainers, and medical professionals who share their insights on weight loss injections and other methods. Visitors can access articles, videos, and interactive tools to better understand their weight loss options.

User Success Stories

Real-life success stories are a testament to the effectiveness of weight loss injections and other methods discussed on Mounjaro Weight Loss. Readers can find inspiration and motivation from individuals who have achieved remarkable transformations.

The Effectiveness and Safety of Weight Loss Injections

The Science Behind Weight Loss Injections

To understand the effectiveness of weight loss injections, it's essential to delve into the science behind them. These injections often target specific hormonal pathways or metabolic processes to promote weight loss. Saxenda, for example, mimics a hormone that regulates appetite.

Weighing the Pros and Cons

Like any weight loss method, weight loss injections have their pros and cons. It's crucial to consider factors such as potential side effects, cost, and long-term sustainability before embarking on this journey.

Pros of Weight Loss Injections

Rapid Results: Some injections, when combined with a healthy lifestyle, can lead to rapid weight loss.

Convenience: Injections are generally easy to administer and can be integrated into a busy urban lifestyle.

Appetite Control: Many injections help in reducing cravings and controlling appetite, making it easier to stick to a healthy diet.

Cons of Weight Loss Injections

Cost: The expenses associated with weight loss injections can add up over time.

Potential Side Effects: Some individuals may experience side effects like nausea, diarrhea, or injection site reactions.

Not a Long-Term Solution: Weight loss injections may not address the root causes of obesity, and their long-term effectiveness is still under study.

The Future of Weight Loss in NYC

The Evolving Landscape

As New Yorkers continue to seek effective weight loss solutions, the landscape of weight management in the city is evolving. Advances in medical research and technology are likely to bring about new and improved methods for achieving and maintaining a healthy weight.

The Role of Mounjaro Weight Loss

Mounjaro Weight Loss will undoubtedly play a pivotal role in disseminating information about these emerging weight loss techniques. Their commitment to providing accurate, evidence-based information will empower individuals to make informed choices about their health.

Conclusion

New York City's hustle and bustle may have contributed to its battle with obesity, but it's also the birthplace of innovative solutions like weight loss injections. As the city strives for healthier lifestyles, websites like Mounjaro Weight Loss serve as invaluable resources, guiding New Yorkers toward safe and effective weight management strategies. The future of weight loss in NYC is promising, with a combination of medical advances and trusted information sources leading the way.

In the city that never sleeps, achieving a healthier weight is not just a dream—it's a reality within reach, thanks to the convergence of science, technology, and dedicated resources like Mounjaro Weight Loss.

Whether you have questions about weight loss injections, need personalized advice, or simply want to share your own success story, we're here to listen and help. Your path to a healthier lifestyle begins with a single message or call.

Remember, you're not alone in your journey to a healthier, happier you. Contact us today and let's take the first step together. Your health and well-being are our top priorities, and we look forward to being a part of your success story.

#lose stomach weight #weight loss #weight loss injections #weightlossgoals #lose weight

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callsignbaphomet · 2 years ago

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Just got home from my appointment with my nutritionist and it went so good. I love her so much! She hadn’t seen my lab results yet so she was totally shocked and happy. She gave me another cute little gold star sticker because of how well my lab results were. She’s so sweet. I told her about the Mounjaro situation and she said that yeah, because of non-diabetics abusing it they saw it was making them money so they stopped covering it but she did say that eventually doctors are gonna stop prescribing it to their patients and she said since I was sticking to the plan I wouldn’t need it for that much longer. I won’t lie, it feels like it helped my blood sugar a lot and as a side effect it did help speed up my weight loss but since I’m still losing weight it shouldn’t be a hard requirement but I still gotta wait to see what my endocrinologist will say in March.

So after that I waited for my mom because she had an appointment with her as well, so we went out to this super cute cafe I know of and we had lunch there. Tuna sandwich with some seriously good and fresh salad and an iced latte with a hint of lavender which was to die for! One of my tires flattened a bit but we managed to fix it and left mom at the office. She said she loved her and I’m so happy cuz mom’s had it rough with doctors as of late. She completely validated and congratulated mom for trusting her instincts when it comes to doctors. Mom’s been dying to replace her endocrinologist cuz she doesn’t listen to her and doesn’t give her enough information so my nutritionist said it’s good to drop doctors if you feel they aren’t doing a good job or benefiting you. Mom loved that and she has an appointment with a new endocrinologist on Monday and my nutritionist told mom that if she doesn’t like them to give her a call because she has some really good ones she can recommend for her. She also told mom that I was doing a fantastic job and that I’m adorable <3 <3 <3 That made my week :D

So yeah, I feel loads better after speaking to her about all this and her encouragement is so genuine and so full of love that I honestly feel like I can tackle this even without the help of the medication.

#werewolf howls at dusk

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weightlosshub49 · 1 year ago

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3 Popular Well-Known mounjaro Weight Loss Programs Examined

There are numerous diets available for losing weight. While others focus on reducing appetite, others restrict their intake of calories, carbohydrates, or fat.

It might be challenging to decide which ones are worthwhile to test because they all assert that they are superior. The reality is that there isn't a single diet that works best for everyone, and what works for you might not work for someone else. This article examines the evidence supporting the top 3 mounjaro weight loss diets.

Diets Low in Carbs

Low-carb diets have grown in popularity over the years, especially for weight loss. Although low-carb diets come in many forms, all recommend limiting daily carbohydrate intake to 20–150 grammes. The fundamental goal of the diet is to make your body rely more on fats for fuel rather than primarily on carbohydrates.

Low-carb diets place a strong emphasis on protein and fat, with carbohydrate intake tightly constrained. When you eat very few carbohydrates, your blood is pushed to your liver, where part of the fatty acids are converted to ketones. In the absence of carbohydrates, your body can then use fatty acids and ketones as its main energy sources.

Low-carb diets are highly effective for weight loss, especially in overweight and obese people, according to a number of studies. They appear to be particularly successful at shedding the harmful belly fat that can collect around your organs. On very low-carb diets, people frequently enter a state known as ketosis. Numerous studies have shown that compared to low-fat, calorie-restricted diets, ketogenic diets provide weight

loss that is more than twice as great. Low-carbohydrate diets have the tendency to decrease your appetite and make you feel less hungry, which results in a natural decrease in calorie intake. In addition, numerous significant disease risk factors, including blood triglycerides, cholesterol levels, blood sugar, insulin levels, and blood pressure, may benefit from low-carb diets. Not everyone should follow a low-carb diet. While others feel horrible on them, some feel fantastic.

It's possible for some people to have higher levels of "bad" LDL cholesterol.

Very low-carbohydrate diets can result in nondiabetic ketoacidosis, a condition that is relatively uncommon. This condition, which seems to affect lactating mothers more frequently, can be fatal if left untreated.

A very low-fat diet

An ultra-low-fat diet limits your daily calorie intake of fat to less than 10%. A low-fat diet typically contains 30% of its calories as fat. Studies show that this diet is ineffective for maintaining weight loss. The ultra-low-fat diet's proponents assert that typical low-fat diets do not contain enough fat and that for weight loss and health advantages, fat consumption must be less than 10% of total calories. 10% or fewer of the calories in an ultra-low-fat diet come from fat.

The diet is mostly plant-based, with a small quantity of animal items. As a result, it often contains little protein (about 10% of calories) and a lot of carbohydrates (approximately 80% of calories). When it comes to helping obese people lose weight, this diet has been quite effective. One study found that obese people shed an average of 140 pounds.

Inflammation indicators, high blood pressure, high cholesterol, and other risk factors for heart disease may all be improved by ultra-low-fat diets, according to studies. Surprisingly, type 2 diabetes can significantly improve as a result of this high-carb, low-fat diet.

Vegetarian diet

The vegan diet prevents consuming any animal products for moral, environmental, or health reasons. Veganism is also linked to opposition to animal abuse and exploitation. The strictest type of vegetarianism is veganism.

It also forbids the use of dairy, eggs, and anything derived from animals, including gelatin, honey, albumin, whey, casein, and several types of vitamin D3. A vegan diet's extremely low fat and high fibre content may help you feel satiated for longer, which may make it incredibly successful at helping individuals lose weight frequently without counting calories.

According to one study, vegan dieters shed 9.3 pounds (4.2 kg) more weight than those following a control diet. The control group had to limit their calorie intake, whereas the vegan group was free to eat until they were satisfied. Vegan diets, as compared to other diets, do not produce greater weight loss results per calorie.

Weight loss on vegan diets is mostly brought about by a reduction in caloric intake. Other advantages include a lower risk of developing heart disease, type 2 diabetes, and early mortality. Limiting processed meat may also lower your risk of Alzheimer's, heart disease, and cancer-related death.

Vegan diets may be deficient in a number of minerals, including vitamin B12, vitamin D, iodine, iron, calcium, zinc, and omega-3 fatty acids because they fully forgo animal products.

my motivations to lose weight!!

so i wont compare myself as much to others

so i will be able to always fit cute, small clothes

so i wont worry about my stomach

so people will like me more

so if a boy ever likes me ill be small and dainty for him

so people will be amazed at how small i am

so people wont even believe i can weigh so little

looking cute and thin in pretty dresses!!

summer/warm weather!!

so i can learn to love myself

so i can feel happy

so i will look effortlessly good because of how small i will be

so i can be guys' crushes

so people will admire me

so people will talk to me more

so people will worry about me

so i can be small and fragile

so people might be jealous

revenge on the guy who played w me (bonus!)

and also..

so i can workout without hating it

so i can be less hungry

so i will have more self-control

so i will be more active

so i will look good in photos and videos

I am determined to do this, even if I fail one day, I will get on track the next.

#weightloss #weight loss #tw ed diet #motivation #i want to be weightless #lose weight #wellness #losing weight #weight loss diet #diet

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usascripthelpersofficial · 1 day ago

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Mounjaro (Tirzepatide) is a medication prescribed to manage type 2 diabetes and support weight loss in some individuals. It works by regulating blood sugar levels and reducing appetite, making it an effective tool for people looking to improve their health. Like most medications, Mounjaro is taken on a specific schedule, often as a weekly injection. However, some patients wonder if it is possible or safe to take Mounjaro a day early. Understanding how this medication works, why timing matters, and the potential effects of adjusting your schedule can help you use it correctly and get the best results.

How Does Mounjaro Work?

Mounjaro works by mimicking the actions of certain hormones in the body, specifically GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide). These hormones help regulate blood sugar levels, slow down digestion, and reduce hunger. By doing so, Mounjaro improves blood sugar control and supports weight loss.

The medication is designed to be injected once a week, providing a steady effect over several days. The weekly schedule is based on the drug’s half-life, which is the time it takes for half of the medication to leave your body. Sticking to the prescribed schedule helps maintain stable levels of the drug in your system, which is essential for consistent blood sugar control and appetite regulation.

Why Is Timing Important When Taking Mounjaro?

Timing is crucial when taking Mounjaro because the medication is designed to work over a specific period. Taking it too early or too late can affect how well it controls blood sugar and appetite. The once-weekly schedule ensures that the drug remains at effective levels in your body without overlapping doses or creating gaps in treatment.

Adhering to the timing also helps prevent potential side effects, such as nausea, digestive discomfort, or low blood sugar (hypoglycemia). Skipping or delaying doses could reduce the medication’s effectiveness, while taking doses too close together might increase the risk of side effects.

Can You Take Mounjaro a Day Early?

Yes, it is generally possible to take Mounjaro a day early, but it should only be done occasionally and with the approval of your doctor. Adjusting the schedule by one day is unlikely to cause significant issues, as the medication is long-acting and remains in your system for an extended period. However, making frequent changes to your dosing schedule can disrupt the consistency of your treatment and may reduce the effectiveness of Mounjaro.

If you need to take your dose a day early, talk to your healthcare provider first. They can advise you on whether it is safe to do so based on your medical history, blood sugar levels, and treatment goals. Your doctor can also help you adjust your schedule if you need to make long-term changes.

What Happens If You Take Mounjaro Early?

Taking Mounjaro a day early on rare occasions is unlikely to cause harm, but it can have some effects on your body. These may include:

Blood sugar levels: Your blood sugar may be better controlled initially, but if doses are taken too close together, there could be a risk of hypoglycemia (low blood sugar).

Digestive symptoms: Some patients may experience side effects like nausea, bloating, or stomach discomfort if doses overlap too closely.

Disrupted schedule: Taking the medication early could shift your weekly schedule, making it harder to stick to a routine in the future.

If you accidentally take Mounjaro early or feel unsure about how it affects you, contact your doctor for guidance.

How to Handle Missed Doses of Mounjaro

While taking Mounjaro early may be an option in some cases, missing a dose entirely can also happen. If you miss your scheduled dose, take it as soon as you remember, provided it is within 4 days of the missed dose. If more than 4 days have passed, skip the missed dose and continue with your regular schedule.

Do not double up doses to make up for a missed injection, as this can increase the risk of side effects. Keeping a reminder system, like setting alarms or using a medication tracker app, can help you stay consistent with your schedule.

Tips for Sticking to Your Mounjaro Schedule

Consistency is key to getting the most out of Mounjaro. Here are some tips to help you stay on track:

Choose a set day: Pick a specific day of the week for your injection and stick to it.

Set reminders: Use alarms, phone notifications, or a calendar to remind you of your injection day.

Prepare in advance: Keep your medication in a designated spot and ensure you have everything ready, such as alcohol swabs and a sharps container.

Talk to your doctor: If you need to change your schedule, discuss it with your healthcare provider to ensure it won’t affect your treatment.

Are There Risks in Taking Mounjaro Early?

While taking Mounjaro a day early is generally safe when done occasionally, there are risks if it becomes a frequent habit. These risks include:

Reduced effectiveness: The medication may not work as well if doses are taken inconsistently.

Increased side effects: Taking doses too close together could lead to more pronounced side effects, such as nausea or low blood sugar.

Confusion with schedule: Adjusting your schedule too often can make it harder to remember when to take your medication.

Always consult your doctor before making changes to your dosing schedule.

How to Safely Adjust Your Mounjaro Schedule

If you need to take Mounjaro early due to travel, work, or other reasons, plan ahead with your healthcare provider. They can guide you on how to adjust your schedule safely. In some cases, they may recommend temporary changes to your dosing time to accommodate your needs while keeping your treatment effective.

Final Thought

Taking Mounjaro a day early is generally safe for most patients when done occasionally, but it’s important to consult your doctor first. Consistency is key to getting the best results from this medication, so sticking to your regular schedule as much as possible is essential. If you need to adjust your schedule, talk to your healthcare provider for guidance.

For reliable and affordable access to Mounjaro, buy Mounjaro at USA Script Helpers, a trusted pharmacy partner. Staying consistent with your treatment and maintaining open communication with your doctor will help you achieve better health and reach your goals effectively.

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fitsurges · 1 day ago

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What to expect in your first month on tirzepatide? 🗓️

Week 1: Body adjusting Week 2: Appetite changes Week 3-4: Initial results Consistent progress starts! Pro tip: Track your journey! 📱

#weight loss journey #healthylifestyle #fitnessgoals #weight loss #gaining weight on purpose #health and wellness

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myhealthybody123 · 8 days ago

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10 Proven Tips for Effective Weight Loss

Losing weight can feel like a daunting task, but with the right approach and mindset, it’s entirely achievable. Whether you're just beginning your weight loss journey or have hit a plateau, incorporating a few key strategies into your routine can help you achieve your goals faster. Here are 10 proven tips to help you shed those extra pounds effectively:

Set Realistic Goals Start by setting achievable and realistic goals. Instead of aiming to lose a large amount of weight all at once, focus on smaller milestones. This will keep you motivated and make the process feel less overwhelming.

Focus on Balanced Nutrition A healthy diet is essential for weight loss. Opt for a balanced mix of proteins, healthy fats, and whole carbohydrates. Prioritize nutrient-dense foods like fruits, vegetables, lean meats, and whole grains while limiting processed foods and sugary snacks.

Watch Your Portion Sizes Even healthy foods can contribute to weight gain if consumed in large quantities. Use smaller plates to control portion sizes, and try to eat slowly to allow your body time to signal when it's full.

Stay Hydrated Drinking plenty of water is key to weight loss. It helps curb hunger, boosts metabolism, and aids in digestion. Try to drink at least 8 glasses of water a day, and consider replacing sugary drinks with water or herbal teas.

Incorporate Regular Exercise Exercise is one of the most effective ways to burn calories and support weight loss. Aim for a combination of cardio exercises (like walking, running, or cycling) and strength training to build muscle and increase metabolism.

Get Enough Sleep Sleep is often overlooked in weight loss plans, but it plays a critical role. Lack of sleep can lead to weight gain by affecting hunger-regulating hormones and increasing cravings. Aim for 7-9 hours of quality sleep each night.

Track Your Progress Keep a journal or use a fitness app to track your meals, workouts, and progress. Monitoring your habits can help you identify areas for improvement and celebrate your successes along the way.

Manage Stress Effectively Stress can lead to emotional eating and poor decision-making when it comes to food choices. Practice stress-management techniques such as deep breathing, meditation, or yoga to stay calm and in control.

Consider Professional Support If you're struggling to lose weight on your own, seeking professional help may be beneficial. Consulting a nutritionist or a weight loss specialist can provide personalized advice tailored to your unique needs. For example, if you're in the Scottsdale area, exploring options like Mounjaro Scottsdale could be a potential path to weight loss under medical guidance.

Stay Consistent and Patient Weight loss takes time, and consistency is key. Stay patient, stick to your healthy habits, and don’t get discouraged by minor setbacks. Celebrate small victories, and remember that every step brings you closer to your goal.

By implementing these tips into your daily routine, you can set yourself up for lasting success on your weight loss journey. Focus on gradual changes that you can maintain long-term, and you'll soon see the results you're working for.

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weightlosshub49 · 1 year ago

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3 Popular Well-Known mounjaro Weight Loss Programs Examined

There are numerous diets available for losing weight. While others focus on reducing appetite, others restrict their intake of calories, carbohydrates, or fat.

Diets Low in Carbs

Low-carb diets have grown in popularity over the years, especially for weight loss. Although low-carb diets come in many forms, all recommend limiting daily carbohydrate intake to 20–150 grams. The fundamental goal of the diet is to make your body rely more on fats for fuel rather than primarily on carbohydrates.

It's possible for some people to have higher levels of "bad" LDL cholesterol.

A very low-fat diet

Vegetarian diet

Vegan diets may be deficient in a number of minerals, including vitamin B12, vitamin D, iodine, iron, calcium, zinc, and omega-3 fatty acids because they fully forgo animal products.

workout channels 🎀

focuses on pilates and/or yoga

Bailey Brown

Boho Beautiful Yoga

Dansique Fitness

Fit by Lys

Gayatri Yoga

Jessica Richburg

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Moving Mango Pilates

focuses on strength and weight training

Caroline Girvan

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Madfit

focuses on slimming bodyweight exercises

April Han

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DN.Beauty Natural

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Home Fitness Challenge

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a mix

Eleni Fit

Emkfit

growwithjo

Pamela Reif

#weight loss #health #growth #weight loss tips #weightloss #lose weight #losing weight #weight loss diet

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vitavenaus · 11 days ago

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From Athletes to Everyday Heroes: How Maryland IV Therapy Revolutionizes Health

In today’s fast-paced world, maintaining optimal health is essential, whether you are a high-performance athlete or simply striving to feel your best in everyday life. Maryland IV Therapy is transforming how individuals achieve and sustain their health goals. VitaVena, a leading provider of personalized health services, brings advanced IV therapy directly to your home or hotel, ensuring convenience and effectiveness. Let’s delve into the incredible benefits of Maryland IV Therapy and how it caters to diverse health needs.

Athlete’s Choice IV Drip: Fueling Peak Performance

Athletes constantly push their limits, and proper recovery is crucial for maintaining peak performance. The Athlete’s Choice IV Drip offered by VitaVena is specifically designed to support athletic recovery, rehydration, and muscle repair. This IV drip provides a carefully balanced blend of electrolytes, vitamins, and amino acids to reduce fatigue and accelerate recovery after intense physical activity. Whether you’re preparing for a big game or recovering from a marathon, Athlete’s Choice IV Drip can give you the competitive edge you need.

Glowup IV Drip Vita: Beauty from Within

Achieving radiant, youthful skin requires more than just topical treatments. The Glowup IV Drip Vita offers a unique blend of nutrients that nourish your skin from the inside out. Packed with antioxidants, hydration, and essential vitamins, this IV drip supports collagen production and skin rejuvenation. For individuals seeking a natural, healthy glow, Glow up IV Drip Vita is the perfect solution, helping you look and feel your best.

Immunity Elixir Vita: Your Defense Against Illness

With busy schedules and constant exposure to environmental stressors, maintaining a robust immune system is critical. The Immunity Elixir Vita provides a powerful boost to your immune defenses, featuring a tailored mix of immune-enhancing vitamins and minerals. Whether you’re preparing for flu season, recovering from illness, or simply looking to strengthen your immunity, this IV therapy is your ally in staying healthy and resilient.

The Power of Maryland IV Therapy

Maryland IV Therapy is a game-changer for individuals seeking fast and effective health solutions. Unlike traditional oral supplements, IV therapy delivers nutrients directly into the bloodstream, ensuring maximum absorption and quicker results. VitaVena takes this innovation a step further by offering mobile IV therapy services, allowing you to receive treatments in the comfort of your home or hotel. This convenience eliminates the need for clinic visits and long wait times, making health optimization accessible to everyone.

Glutathione IV Maryland: The Master Antioxidant

Glutathione, often called the "master antioxidant," plays a vital role in detoxifying the body and combating oxidative stress. The Glutathione IV Maryland treatment offered by VitaVena provides a concentrated dose of this powerful antioxidant, promoting liver health, improving skin clarity, and enhancing overall cellular function. For individuals seeking a natural way to detox and rejuvenate their body, this therapy is a top choice.

Semaglutide Active Ingredient Ozempic: Weight Management Support

Weight management can be challenging, but innovative solutions like Semaglutide Active Ingredient Ozempic are changing the game. Semaglutide is a medication that helps regulate appetite and promote weight loss by targeting areas of the brain that control hunger. VitaVena incorporates this active ingredient into its weight management programs, providing a science-backed approach to achieving and maintaining a healthy weight. Combined with personalized dietary guidance, this therapy empowers individuals to take control of their health.

Tirzepatide Active Ingredient Mounjaro: Comprehensive Health Benefits

For those seeking comprehensive metabolic support, the Tirzepatide Active Ingredient Mounjaro offers significant benefits. This innovative therapy aids in blood sugar regulation, weight management, and improving insulin sensitivity. By incorporating Tirzepatide into its offerings, VitaVena provides clients with cutting-edge solutions that address multiple health concerns simultaneously. Whether you’re managing diabetes or looking to enhance metabolic health, this treatment can be a valuable tool in your journey.

Why Choose VitaVena for Maryland IV Therapy?

VitaVena stands out as a leader in Maryland IV Therapy by combining expertise, convenience, and personalized care. The handpicked team of licensed contracted nurses ensures each client receives top-quality care tailored to their unique needs. VitaVena’s mobile services bring health and well-being directly to your doorstep, eliminating the hassle of traveling to a clinic.

With a range of IV drips and dietary solutions, VitaVena caters to various health goals, from boosting immunity and improving athletic performance to supporting weight management and enhancing overall vitality. Their commitment to delivering exceptional care makes them a trusted partner for individuals across Maryland.

How Maryland IV Therapy Benefits Everyday Heroes

Everyday heroes, such as parents, caregivers, and professionals, face daily challenges that require energy and resilience. Maryland IV Therapy offers a practical solution for maintaining health amidst busy lifestyles. Whether you’re looking to recharge with an Immunity Elixir Vita or prioritize self-care with a Glowup IV Drip Vita, VitaVena provides the tools to help you thrive.

Convenience Meets Expertise with VitaVena

The convenience of VitaVena’s services sets them apart from traditional healthcare options. With mobile IV therapy, clients can schedule treatments at times and locations that fit their busy schedules. The combination of expert care and unparalleled convenience makes it easier than ever to prioritize health and well-being.

Transformative Results for All

From athletes seeking enhanced performance to individuals managing chronic conditions, Maryland IV Therapy offers transformative benefits for all. VitaVena’s commitment to personalized care ensures each treatment is tailored to the client’s specific needs, delivering results that make a tangible difference in their lives.

Take the First Step Toward Better Health

Whether you’re an athlete, a busy professional, or someone striving to improve their health, Maryland IV Therapy has something to offer. VitaVena’s range of IV drips and dietary solutions provides a holistic approach to health and well-being, empowering clients to achieve their goals with ease and confidence.

To learn more about VitaVena’s innovative services or to schedule your first IV therapy session, visit website at vitavenaus.com. With options like the Athlete’s Choice IV Drip, Glowup IV Drip Vita, and Immunity Elixir Vita, the path to better health is just a click away.

Conclusion

Maryland IV Therapy is revolutionizing health by offering fast, effective, and personalized solutions for a wide range of needs. VitaVena’s mobile services and commitment to excellence make advanced IV therapy accessible to everyone, from athletes aiming for peak performance to everyday heroes looking to enhance their vitality.

Experience the power of IV therapy and take control of your health with VitaVena. Contact them today and embark on a transformative journey towards a healthier, more vibrant you.

#Athlete’s Choice IV Drip #Glowup IV Drip Vita #Immunity Elixir Vita #IV Drip Revive RX #Migraine Mastery Vita #Nad + IV Therapy #Night-Time Nirvana #Rehydrate IV

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boome11 · 12 days ago

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One of Dr Mo Sarhan’s patients was experiencing intense cravings for opioids and alcohol when the Florida-based doctor offered him a striking solution: the Eli Lilly weight-loss drug Mounjaro.“Within days, all of his cravings were gone and he was much more effective in his engagement and treatment. He’s done great since,” Sarhan says. Sarhan and his colleague Steven Klein at the Caron Treatment Centers in Florida and Pennsylvania have prescribed a range of so-called glucagon-like peptide-1 receptor agonists (GLP-1s) to treat addictions, using them alongside traditional therapies, to around 75 patients. The results, which Sarhan describes as “compelling”, are the latest sign that drugs such as Mounjaro, Ozempic and Wegovy could be effective treatments for a startlingly wide range of conditions well beyond their original focus on obesity and diabetes.On Tuesday, Dave Ricks, Eli Lilly’s chief executive, said the company would begin large studies of GLP-1s in alcohol, nicotine and drug abuse — the first pharmaceutical group to do so. “These medicines, we think and we’ve aimed to prove, can be useful for other things we don’t think about connected to weight,” he told the Economic Club of Washington DC.While GLP-1s are not clinically approved for addiction treatment, preliminary studies suggest they reduce cravings by acting on pleasure pathways in the brain — similar to the mechanism that dampens appetite.In recent years, GLP-1s have helped transform the waistlines of patients and the top lines of pharmaceutical groups Novo Nordisk and Eli Lilly. Worldwide, more than 1bn people are defined as obese, according to research published this year in The Lancet, with rates doubling for adults and quadrupling for children and adolescents between 1990 and 2022. Conditions linked to obesity, such as chronic kidney disease and diabetes, are increasingly prevalent too.Some content could not load. Check your internet connection or browser settings.According to data provider Airfinity, there are 66 ongoing, late-stage trials of GLP-1 drugs for obesity, diabetes and a range of other conditions linked to excess weight. The prospect of broader uses for the drugs is one reason that Goldman Sachs analysts anticipate a $130bn market for them by 2030.But there are also ongoing studies in treatment areas with few apparent links to excess weight. Novo Nordisk is running three late-stage trials of semaglutide, the active ingredient in its Ozempic and Wegovy drugs, for Alzheimer’s disease. Another of the class of drugs, lixisenatide, has shown some early promise in slowing the worsening of motor symptoms in Parkinson’s disease patients. Widespread uptake of the drugs could help tackle the rising tide of chronic diseases across the world and lower the costs associated with them for health systems. In one example, Airfinity estimates that Wegovy could prevent up to 3.8mn cases of obstructive sleep apnoea, a breathing disorder, in the US by 2030. That could cut expenditure on the CPAP (continuous positive airway pressure) machines used to help patients manage symptoms in the US by up to $3bn. Sarhan’s patients, most of whom pay for the drug themselves and are all informed beforehand of its regulatory status, have taken the treatments for addiction to nicotine, inhalants and alcohol. But the therapeutic mechanisms of the drugs are not yet fully understood and many of the benefits have not been verified in late-stage trials. Production of GLP-1s is currently dominated by Novo Nordisk and Eli Lilly, which have much more incentive to maximise the revenue potential of the obesity market than to spend on experimental clinical trials in unproven treatment areas. And the hefty price tags and unpleasant side effects associated with current weight-loss treatments mean they are not yet a panacea for the growing body of chronic health conditions across the world.Lower-priced, more widely available drugs that could be taken orally are “the direction of travel,” says Naveed Sattar, professor at the University of Glasgow and chair of the UK government’s obesity mission. “But we are not there yet — because the drugs are too expensive.” GLP-1 receptor agonists have surprised scientists before. The gut hormone was originally discovered in the 1980s, but found to break down quickly in the body. It was not until researchers discovered a similar but more stable compound in the venom of the Gila monster, a lizard native to North America, that they were able to produce long-lasting drugs mimicking GLP-1’s effects. The first GLP-1 based drug was approved in 2005.Early GLP-1s were developed as diabetes treatments owing to their ability to stimulate insulin production, with weight loss initially a useful side effect. Previous treatments for obesity itself came with dangerous side effects. The “fen-phen” cocktail of an appetite suppressant and amphetamine was withdrawn in 1997 after its use was linked to heart valve defects. Novo Nordisk is running late-stage trials of semaglutide, the active ingredient in its Ozempic and Wegovy drugs, for Alzheimer’s disease © Steve Christo/Corbis/Getty ImagesRather than increasing cardiovascular risk, GLP-1s have shown impressive benefits. Last year, Novo Nordisk unveiled data that suggested semaglutide cut the risk of heart attacks by 28 per cent in its so-called Step trial of 17,604 patients, and reduced the risk of death by 18 per cent. The results of the trial have helped expand the drugs’ usage. In March, Novo Nordisk secured US approval for Wegovy to reduce the risk of heart attacks and strokes in overweight or obese adults with cardiovascular disease.“It’s a complete turnaround from what we’ve had before,” says Vlado Perkovic, a renal specialist at UNSW Sydney, who has done research on the impact of GLP-1s on kidney conditions. Trials show the drugs are effective in treating both chronic kidney disease and metabolic dysfunction-associated steatohepatitis or Mash, a liver disease. Meanwhile, Eli Lilly’s Mounjaro has slashed the severity of sleep apnoea, a breathing disorder, by nearly two-thirds and cut heart failure outcomes in a separate trial.Sattar, the University of Glasgow professor, says weight loss alone is a major driver of improvements across each of these disease areas. “The weight loss attributes of the drugs are responsible for most of the benefits in multiple diseases, or are the predominant reason why these drugs affect multiple diseases,” he says. As new and stronger drugs emerge, these effects are likely to increase. Novo Nordisk’s chief executive Lars Fruergaard Jørgensen said last month he was “very excited” about the potential of the company’s new CagriSema drug on diseases linked to obesity. Upcoming data is expected to show the drug delivers 25 per cent weight loss on average, an increase from the 22 per cent attributed to Mounjaro.Danish professor Jens Juul Holst was among the first to identify the GLP-1 hormone in 1986, and sees the new crop of GLP-1s as similar in impact to bariatric surgery, a procedure to shrink stomach volume.“The effects are becoming more and more clear, and now there’s no doubt that with the rate of weight loss you have, you also will have a real solution for steatosis [excess liver fat] in many individuals,” says Holst.But weight loss alone does not explain the drugs’ benefits. Both Holst and Sattar pointed to a discontinued GLP-1 drug once marketed by GSK, albiglutide, that did not provide any weight loss in clinical trials, but led to cardiovascular benefits for patients. There are GLP-1 receptors throughout the body and researchers believe the drugs could also have direct effects on organs and lead to health improvements other than through weight loss.Recent trials exploring the effects of semaglutide in diabetics with chronic kidney disease showed a 24 per cent reduction in outcomes such as kidney failure for patients taking the drug.“Weight loss may well be a contributor, but it would appear unlikely to be the whole explanation,” says Perkovic. The drugs also lower inflammation in the body, which has been linked to better cardiovascular outcomes, while they could also be having “direct effects” on the kidneys, such as improving blood flow and reducing pressure in the kidney blood vessels, he adds.Knowledge about the exact reasons for improved health outcomes is likely to increase as the drugs are more widely prescribed and drugmakers conduct larger studies.“There will be a continuous flow of new results . . . which may or may not provide better explanations for exactly what goes on,” says Holst.The wide-ranging action of GLP-1s has also triggered a search for still broader therapeutic frontiers. One of the most intriguing is a late-stage trial of semaglutide in Alzheimer’s patients, with initial results expected in 2025. It follows early findings that patients with type 2 diabetes were less likely to develop Alzheimer’s disease if they were receiving GLP-1 medications.Success would be “freaking nuts,” says one biotech investor, while noting that neurological disorders have for decades defied treatment. One pharmaceutical executive said scientists at his company were “sceptical” that the trial would bring positive results, partly because the drugs are not yet proven to cross the blood-brain barrier, a semi-permeable membrane that protects the brain.Holst says “the most logical” way of explaining the potential benefits is through the lowering of inflammation and improvements in circulation. But it is still too soon to say whether GLP-1s offer a pioneering way to treat disorders afflicting growing numbers of people as societies age. Studies exploring the drugs’ effects in combating Parkinson’s disease have also had mixed results. French scientists unveiled a study in April suggesting that lixisenatide — a GLP-1 diabetes drug — could slow the impact of the brain disorder, which causes balance and movement problems and other symptoms. Patients who took the medicine exhibited no further worsening of their motor symptoms after a one-year trial.But exenatide, which had shown potential in an earlier trial of Parkinson’s patients, flopped in a new one reported in October. Olivier Rascol, co-author of the French study of lixisenatide, says the drug is quite similar in structure to exenatide, making it hard to explain why a trio of trials yielded such contrasting results.“Nobody really has a clear explanation for [the] negative outcomes,” says Rascol, a Toulouse University Hospital professor and co-ordinator of the French NS-Park network for Parkinson’s research.The Parkinson’s conundrum highlights wider gaps in knowledge about how GLP-1s work against brain disorders. Evidence for their effectiveness in treating addiction, for instance, has largely come from looking back at health records and observing that patients with addictions were less likely to overdose if they were using GLP-1s. Sue Grigson, a scientist at Penn State University Hospital who has worked on small studies in opioid-use disorder, is among those exploring the links. She has observed a lower dopamine response when patients were using GLP-1s, indicating that the effect of the “feel-good” hormone is damped by the drugs. Grigson said the drugs appear to have an effect on the circumventricular organs — the parts of the brain not protected by the blood-brain barrier — and this may influence brain function. But much remains unknown about the drugs’ impact on neurological conditions. “This is still very much in infancy,” Rascol says, of the understanding of how GLP-1s affect the brain. “There will be more . . . experiments to better explore the real effects of these compounds.”While scientists continue to explore their potential, pharmaceutical companies are already cashing in on GLP-1s’ broader health benefits.Eli Lilly is seeking US regulatory approval for Mounjaro as a treatment for sleep apnoea, while Novo Nordisk has filed an application for Wegovy in chronic kidney disease.“There’s a reason why companies have gone for these diseases where they think the weight loss plus or minus the direct effect may have a benefit,” says Sattar. “Guess what? The reality proves that to be the case.” Upfront costs of GLP-1s are likely to hold back the wide-ranging access needed if the treatments are to tackle cardiometabolic diseasesBut large-scale trials are expensive and securing extra approvals could entrench the early movers’ grip on the GLP-1 market. “Novo and Lilly are going to cement their lead here,” said one investment banker.Adam Steensberg, the chief executive of Danish biotech Zealand Pharma, which is developing an alternative weight loss product based on a different hormone, says “there is a duopoly already” in the GLP-1 market. Combining different drugs could be a way of expanding the effects of GLP-1s further still. Doctors such as Perkovic envisage a possible future treatment regime for chronic kidney disease patients that combines existing drugs with GLP-1s to drastically reduce the risks of organ failure. But the upfront costs of GLP-1s are likely to hold back the wide-ranging access needed if the treatments are to tackle cardiometabolic diseases across the world. The US list price of Wegovy is $1,349 for a one-month course. The cost of preventing one major adverse cardiovascular event, such as a heart attack or stroke, is likely to be almost $1.3mn, Airfinity predicts. This estimate assumes such an outcome would on average require 67 people to be treated for over three years, with the drugs available at a large discount to the list price.Side-effects including nausea, diarrhoea and fatigue also remain a problem for some users, a challenge drugmakers and physicians are attempting to address. BlueHealth Intelligence, a health insurer in the US, found that 30 per cent of GLP-1 users in the US were discontinuing their usage within a month, with poorer patients more likely to stop taking their drugs.Glasgow University’s Sattar sees a “distant future” where lower-priced GLP-1s can be given to patients orally at the onset of conditions such as diabetes, tackling both obesity and other negative consequences in a way that doesn’t “bankrupt the health system”.While progress is being made on cardiometabolic conditions, Ricks’ comments are the first sign that pharmaceutical companies will undertake clinical trials in areas such as addiction. Even if scientists establish a link, the road to an approval for use here is long.The head of the US National Institute on Drug Abuse, Nora Volkow, points out that treating addiction may not be a commercial priority for pharmaceutical groups. GLP-1s are already generating big sales for Novo Nordisk and Eli Lilly, but many obese patients are yet to receive them — so there is still a huge target market. “It may be hard, if the pharmaceutical industry says ‘why should I care? I make much more money prescribing these things for obesity’,” Volkow says. Additional reporting by Oliver Barnes in New York https://www.ft.com/__origami/service/image/v2/images/raw/https%3A%2F%2Fd1e00ek4ebabms.cloudfront.net%2Fproduction%2F96b4551a-5c5a-4d34-93df-2645d062d9f1.jpg?source=next-article&fit=scale-down&quality=highest&width=700&dpr=1 2024-12-12 05:00:47

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lindamarry1 · 1 year ago

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Exploring the Effectiveness and Safety of Weight Loss Medications: A Comprehensive Guide

In today's world, where obesity has become a global epidemic, weight loss medications have gained significant attention as a potential solution. These medications, when used in conjunction with a healthy lifestyle, can assist individuals in achieving their weight loss goals. This comprehensive guide aims to provide an in-depth analysis of the effectiveness and safety of weight loss medications. As we delve into the topic, we will also shed light on Mounjaro weight loss, a reputable website that offers weight loss medications.

Understanding Weight Loss Medications

1.1 Defining weight loss medications

Weight loss medications, also known as anti-obesity drugs, are prescription or over-the-counter medications designed to aid in weight reduction. These medications can be categorized into different types based on their mechanisms of action, such as appetite suppressants, fat absorption inhibitors, and metabolic enhancers.

1.2 Common types of weight loss medications

Some common weight loss medications include phentermine, orlistat, liraglutide, and bupropion/naltrexone. Each medication works differently to help individuals lose weight, whether by reducing appetite, blocking the absorption of dietary fat, or influencing metabolism.

1.3 How weight loss medications work in the body

Weight loss medications target various aspects of the body's physiology to promote weight loss. They may act on the brain to suppress appetite, affect the digestive system to inhibit fat absorption, or impact metabolism to enhance calorie burning.

The Effectiveness of Weight Loss Medications

2.1 Clinical Studies and Evidence

Numerous clinical studies have evaluated the effectiveness of weight loss medications. These studies often compare the outcomes of individuals using medications versus those following a placebo or non-medication intervention. The results show that weight loss medications can lead to greater weight loss compared to lifestyle changes alone.

2.2 Average weight loss with medication

The average weight loss achieved with weight loss medications varies depending on the specific medication and individual factors. However, studies have shown that individuals using weight loss medications, in combination with a reduced-calorie diet and increased physical activity, can expect to lose 5% to 10% of their initial body weight over a period of several months.

2.3 Factors influencing effectiveness

2.3.1 Individual response

The effectiveness of weight loss medications can vary among individuals. Factors such as genetics, metabolism, underlying medical conditions, adherence to medication, and lifestyle changes can influence the degree of weight loss achieved.

2.3.2 Adherence to medication and lifestyle changes

The success of weight loss medications is closely tied to an individual's adherence to the prescribed regimen. Consistently taking the medication as directed, following a balanced and calorie-controlled diet, and engaging in regular physical activity are essential for optimizing the effectiveness of these medications.

Safety Considerations of Weight Loss Medications

3.1 Regulatory Bodies and their role

Before weight loss medications are approved for public use, they undergo rigorous evaluation by regulatory bodies such as the Food and Drug Administration (FDA). These agencies assess the safety and efficacy of the medications based on data from preclinical and clinical trials.

3.2 Common side effects of weight loss medications

Weight loss medications may cause side effects, which can vary depending on the specific medication. Common side effects include nausea, diarrhea, constipation, dry mouth, dizziness, and insomnia. These side effects are generally mild and diminish over time as the body adjusts to the medication.

3.3 Potential risks and precautions

3.3.1 Interactions with other medications

It is crucial to consider potential interactions between weight loss medications and other medications an individual may be taking. Some weight loss medications may interact with certain antidepressants, antidiabetic drugs, or other medications, leading to adverse effects or reduced efficacy.

3.3.2 Allergies and contraindications

Individuals with known allergies to specific weight loss medications should avoid using them. Additionally, weight loss medications may be contraindicated for individuals with certain medical conditions, such as uncontrolled hypertension, heart disease, or a history of substance abuse.

3.3.3 Long-term safety concerns

Since weight loss medications are relatively new, their long-term safety is still being studied. It is important to discuss any concerns or potential risks with a healthcare professional before initiating a weight loss medication regimen.

Mounjaro Weight Loss: A Reliable Source for Weight Loss Medications

4.1 Introduction to Mounjaro weight loss

Mounjaro weight loss is a reputable website that offers a range of weight loss medications. They provide a convenient and reliable platform for individuals seeking medically approved weight loss options.

4.2 Safety Standards and quality control

Mounjaro weight loss adheres to strict safety standards and ensures that all medications available on its platform are approved by regulatory authorities. They source their medications from trusted manufacturers and regularly monitor product quality.

4.3 Available weight loss medications and their effectiveness

Mounjaro weight loss offers a variety of weight loss medications, each with its unique mechanism of action. The website provides detailed information about the medications they offer, including their effectiveness, potential side effects, and usage instructions.

4.4 Customer Testimonials and Reviews

Mounjaro weight loss features customer testimonials and reviews, allowing individuals to gain insights from others who have used their services. These testimonials can provide valuable information about the effectiveness and customer satisfaction associated with the weight loss medications offered by Mounjaro.

Lifestyle Changes and Weight Loss Medications

5.1 Importance of lifestyle modifications

While weight loss medications can be effective, they should be used as part of a comprehensive weight management approach that includes lifestyle modifications. Adopting healthy eating habits, engaging in regular physical activity, managing stress, and getting adequate sleep are crucial for long-term weight management.

5.2 Synergy between weight loss medications and lifestyle changes

Weight loss medications can complement lifestyle changes by providing additional support for appetite control and metabolic regulation. When used in combination with a healthy lifestyle, these medications can enhance weight loss outcomes.

5.3 Incorporating Diet and Exercise for optimal results

To maximize the benefits of weight loss medications, individuals should follow a well-balanced, calorie-controlled diet and engage in regular physical activity. A healthcare professional or registered dietitian can provide personalized guidance and support in developing a suitable diet and exercise plan.

Choosing the Right Weight Loss Medication

6.1 Consultation with healthcare professionals

Before initiating any weight loss medication, it is important to consult with a healthcare professional. They can assess individual needs, consider medical history, and provide guidance on choosing the most appropriate medication based on effectiveness, safety, and potential interactions.

6.2 Assessing individual needs and Goals

Weight loss medications should be tailored to individual needs and goals. Factors such as weight, overall health, medical conditions, and lifestyle should be taken into account when determining the most suitable medication.

6.3 Considering the medical history and potential contraindications

Individuals with certain medical conditions, such as cardiovascular disease, diabetes, or kidney problems, may require specific considerations when selecting a weight loss medication. A thorough assessment of medical history is essential to identify potential contraindications and ensure the chosen medication is safe to use.

Conclusion

In conclusion, weight loss medications can be valuable tools in the journey toward achieving a healthy weight. They can provide an additional boost when combined with lifestyle changes such as a balanced diet and regular exercise. However, it is essential to recognize that weight loss medications are not a one-size-fits-all solution, and careful consideration should be given to safety, effectiveness, and individual circumstances. Mounjaro weight loss stands as a trusted website offering a range of weight loss medications, but it is always advisable to consult with healthcare professionals before starting any medication regimen. By understanding the effectiveness and safety of weight loss medications, individuals can make informed decisions to support their weight loss goals and improve their overall well-being.

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weightlosshub49 · 1 year ago

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3 Popular Well-Known Mounjaro Weight Loss Programs Examined

There are numerous diets available for losing weight. While others focus on reducing appetite, others restrict their intake of calories, carbohydrates, or fat.

Diets Low in Carbs

It's possible for some people to have higher levels of "bad" LDL cholesterol.

A very low-fat diet

Vegetarian diet

It also forbids the use of dairy, eggs, and anything derived from animals, including gelatin, honey, albumin, whey, casein, and several types of vitamin D3. A vegan diet's extremely low fat and high fiber content may help you feel satiated for longer, which may make it incredibly successful at helping individuals lose weight frequently without counting calories.

Vegan diets may be deficient in a number of minerals, including vitamin B12, vitamin D, iodine, iron, calcium, zinc, and omega-3 fatty acids because they fully forgo animal products.

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