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CDC-GuideLines -Vaccines-Me-You-Us-We! The new guidance from the CDC- The center for disease control and prevention based in Atlanta, Georgia. This is a 1st step by the CDC as you read through the guidance you may see some still unanswered guidance still fully explained. I believe all of this will be forthcoming as we learn more. While I do not know anymore than you or anyone else? I am basingâŚ
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5+ Reasons Why B Vitamins Are Part of IV Therapy in Toronto

This post is part of our blog series, â5 Reasons Whyâ, which helps readers understand why IV therapy in Toronto is an option for optimal, natural health. Stay tuned for more posts in this series!
Did you know that there are eight different types of B vitamins?
Each B vitamin is necessary for building energy, reducing fatigue, and supporting brain health. Every B vitamin is involved in at least one or several steps of building energy.
B vitamins and their energy production roles are crucial because they help promote the maintenance and function of the body and brain cells. This is why we need an adequate amount of each B vitamin in the body! If we lack any of these vitamins, our energy production and brain function may face limits; some individuals may even undergo further health consequences.
Your IV therapist or naturopathic doctor may suggest B vitamins in your intravenous (IV) therapy treatments. Here are the B vitamins that might be included in your IV therapy sessions and how each may produce health benefits and assist with improving wellness:
1. B1 (Thiamine)
Known as thiamine, B1 is a cofactor for enzymes that break down glucose and produce energy.
Thiamine is commonly found in fish, nuts, seeds, wheat, cooked asparagus, navy beans and edamame. Our diet may already contain ample amounts of B1, so a deficiency shouldnât occur. âHowever, conditions that lead to altered gastrointestinal function are common and can decrease absorption, including conditions that interfere with thiamine absorption from the intestine,â explains the Annals of the New York Academy of Sciences. For instance, people with gluten sensitivity may not absorb B1, especially since foods with small amounts of gluten tend to remove vitamin B1.
A B1 vitamin deficiency may lead to memory loss, disorientation, amnesia and a decline in working memory. In fact, â[m]ultiple similarities exist between classical thiamine deficiency and Alzheimerâs disease (AD) in that both are associated with cognitive deficits and reductions in brain glucose metabolism,â confirms the Annals of the New York Academy of Sciences.
Your IV therapist or naturopathic doctor may suggest IV vitamin infusions of B1 to help lessen thiamine deficiencies or endorse cognitive function. If you excessively drink alcohol, your B1 levels may diminish; this is because drinking alcohol encourages B1 to flush out via urine. So if you have been diagnosed with a B1 deficiency due to alcoholism, this is also why intravenous treatments of B1 may be recommended.
2. B2 (Riboflavin)
Interestingly, riboflavin (vitamin B2) is linked to cognition. In a study of elderly patients with mild cognitive impairment, a high vitamin B2 intake resulted in improved cognitive performance on various tests.
For the human body to healthily thrive, riboflavin is needed for developing blood cells, skin health, the digestive tract (lining), and brain function. B2 is an essential component of flavoproteins, coenzymes that metabolize carbohydrates, lipids, and proteins. Riboflavin also aids in the production of energy or ATP (adenosine triphosphate). Side effects of B2 vitamin deficiency may include signs of weakness, inflammation, sores around the mouth, scaly skin, personality change, sore throat, itchy eyes and a sensitivity to light.
If you donât eat enough dairy, meat or fortified cereals, you may be prone to a B2 deficiency. Malabsorption, chronic alcoholism and other chronic disorders may put you at risk of a B2 deficiency, too. Vegetarian athletes may also be at risk as some vegetarian diets dismiss all animal products (i.e. eggs, milk), and these foods tend to be sources of vitamin B2. Thus, intravenous vitamin drips of B2 may be suggested for helping support cognition, promote cellular energy, and recover from a riboflavin deficiency.
3. B3 (Niacin)
Vitamin B3 (niacin) is part of a coenzyme called nicotinamide adenine dinucleotide (NAD+). NAD+ is converted into NADP+, a coenzyme involved in the breakdown of complex substances in the body. The energy released by this breakdown of substances then creates carbohydrates, lipids, and proteins.
Patients diagnosed with Parkinsonâs have been shown to carry low levels of B3. Niacin has been shown to participate in both brain and nervous system function, so your IV therapist may recommend intravenous vitamin drips of B3 to help promote optimal brain function.
Furthermore, â[i]t is now recognized that a deficit of mitochondrial energy metabolism (i.e. impaired mitochondrial phosphorylation potential) plays a role in the pathogenesis of chronic migraine headaches,â confirms Nutrition Journal. Niacin may not only improve cellular energy, but also increase your blood flow (vasodilating the blood intracranial vessels), which may help alleviate migraines. So if youâre prone to migraines, it may be plausible for IV niacinimide (a different biochemical version of B3) and other nutrients (i.e. intravenous B2, IV magnesium and oral CoQ10) to promote the relief of painful headaches, especially since IV vitamin infusion therapy directly enters the bloodstream.
A B3 deficiency may progress to vertigo, memory loss, paranoia, diarrhea, dermatitis, dementia, and more. Neurological symptoms are known to occur with a niacin deficiency. So if youâre concerned about your vitamin B3 levels, please speak to your IV therapist or naturopathic doctor on the possible benefits of vitamin IV drips for your health needs.
4. B5 (Pantothenic Acid)
Vitamin B5 helps build a coenzyme that synthesizes fatty acids, lipids, cholesterol and acetylcholine. A deficiency in pantothenic acid (B5) is rare in healthy patients because the vitamin is found in plant- and animal-rich foods, or it may be already added to prepared foods (i.e. cereals). But a deficiency may occur due to malabsorption.
Signs and symptoms of a B5 deficiency are fatigue or weakness, irritability, gastrointestinal distress, numbness, muscle pain, cramps, brain damage, behavioural change and demyelination. In some cases, this deficiency may cause neurological dysfunction (i.e. confusion). Pantothenic acid may be recommended for your IV vitamin drips to help encourage cellular energy, which may aid in relieving a B5 deficiency.
Although pantethine (an active form of vitamin B5) is not intravenously offered, it is still worth discussing because your naturopathic doctor may recommend this form of vitamin B5 as an oral supplement. In fact, according to the Harvard T.H. Chan School of Public Health, pantethine has been studied for potentially lowering cholesterol in patients with dyslipidemia, a condition in people in which the amount of lipids are either too high or too low in the body.
5. B6 (Pyroxidine)
The human body doesnât have the ability to store this vitamin. Therefore, we need to find vitamin B6 sources on a daily basis to stimulate optimal health.
Pyroxidine (B6) helps synthesize and break down amino acids. It helps release glucose from glycogen, a pathway required by enzymes for synthesizing neurotransmitters and hemoglobin. Vitamin B6 is also required for producing hemoglobin and it even contributes to numerous cellular functions.
In Western diets, a B6 deficiency is infrequent. If there is a B6 deficiency, itâs usually related to a deficiency in other B vitamins (i.e. B12). However, the following patients are at risk of developing a B6 deficiency: those who are geriatric; those with compromised renal function; those who drink excessive alcohol and/or have malabsorption issues.
A pyroxidine deficiency may cause anemia along with low hemoglobin content. The size of the red blood cells are either normal or small, though their capacity for carrying oxygen becomes diminished. This may result in muscle weakness, fatigue, dermatitis, mouth sores, fatigue, confusion, shortness of breath, irritability, impaired alertness, depression, cognitive decline and dementia.
Your IV therapist or naturopathic doctor may recommend IV pyroxidine to help support the treatment of anemia or encourage mental health improvements. âA low level of vitamin B6 has [been linked to depression] as vitamin B6 is a cofactor in the tryptophan-serotonin pathway,â explains Psychotherapy and Psychosomatics. Keep in mind that IV therapy may promote swift results in mood because it enters the bloodstream directly, detouring the digestive system.
6. B7 (Biotin)
Youâve likely seen biotin oral supplements in stores for promoting healthy hair and nails. But did you know that biotin (B7) is also required in the body for several chemical reactions?
Biotin is involved in a series of chemical reactions to release stored energy and metabolize lipids. Itâs also required for synthesizing glucose, fatty acids, and some non-essential amino acids. Biotin may possibly help normalize the functioning of the nervous system, as B7 already plays a role in metabolizing cellular energy.
Biotin deficiency is linked to neurological concerns, such as depression, lethargy, hallucinations, and paraesthesia (tingling/burning sensation) of the extremities. A B7 deficiency may also cause weakness, hair loss, and a rash around the eyes, nose and mouth.
This deficiency may be uncommon for most people, but individuals with excessive alcohol issues or who use certain medications (i.e. antibiotics) may have trouble properly absorbing vitamin B7. So an IV therapist might recommend intravenous biotin to help âtop upâ biotin levels into the bloodstream, bypassing absorption concerns.
7. B9 (in the form of folic acid or methyltetrahydrofolate)
A fraction of our population has a defect in a gene called MTHFR (methylenetetrahydrofolate reductase). This gene directs the construction of the MTHFR protein, which aids the body in processing folate. The body requires folate to create DNA and adjust proteins. The MTHFR gene that codes for this enzyme has the potential to mutate, which can either restrict the enzymeâs ability to function routinely or completely inactivate it.
A defect in this gene may be concerning because the MTHFR protein is compulsory for processing B9 in the body. The MTHFR gene is responsible for breaking down homocysteine, an amino acid that the body requires to construct proteins. Generally speaking, some B vitamins (including folic acid) help break down homocysteine, converting it into further substances that the body may need. But if the MTHFR gene is mutated, homocysteine may accumulate within the blood. This may cause: blood clots, a stroke, heart disease, high blood pressure, or homocystinuria, which is a disorder related to methionine metabolism.
Consequently, your IV therapist or naturopathic doctor may recommend different forms of intravenous folic acid/vitamin B9 to possibly help support mood, detoxification, energy and fertility.
Keep in mind that folate is an essential vitamin for cell growth in the central nervous system. Itâs also a required coenzyme for synthesizing methionine (an amino acid) and for constructing RNA (ribonucleic acid). A folate deficiency may cause the body to experience peripheral neuropathy, spinal cord lesions, psychosis, cognitive decline and dementia. Not to mention, this nutritional deficiency may cause megaloblastic anemia, a condition in which the body cannot properly produce red blood cells. Hence, your IV therapist or naturopath may suggest intravenous folate to aid in improving cellular health and/or to help with correcting MTHFR deficits.
8. B12 (in the form of methylcobalamin, cobalamin, or hydroxocobalamin)
For the body to effectively absorb vitamin B12, the stomach, pancreas and small intestine must be functional. Hence, a B12 IV therapy may be recommended for nutrition and/or malabsorption issues, and also to help support the MTHFR pathways.
Patients diagnosed with poor nutrition and/or Crohnâs disease and vegans or vegetarians may be at risk of a B12 deficiency. Also, B12 malabsorption is frequent among the elderly, who may undergo impaired digestive functioning.
A vitamin B12 deficiency is concerning because the body does not produce vitamin B12, even though the body needs this vitamin. The function of folate, the breakdown of fats, and proteins and the synthesis of hemoglobin all require B12. Cobalamin is also vital for making red blood cells and DNA. A B12 deficiency can cause numerous side effects, such as anemia. This deficiency may trigger further neurological dysfunctions, including myelopathy, neuropathy and neuropsychiatric abnormalities.
Vitamin B12 deficiencies limit the methionine synthase, a key enzyme that helps process amino acids. This limitation may further promote the progression of neurodegenerative disorders (i.e. Alzheimerâs and Parkinsonâs), which is another reason why B12 may arise in a discussion about your IV therapy.
Learn More About B Vitamins and IV Therapy in Toronto
As youâve read, B vitamins contribute to our mental health and cellular energy. Some of us may be lacking these important vitamins, but treatments with intravenous B vitamins may possibly (and swiftly) produce positive effects and encourage optimal health.
Do you think youâre at risk of a vitamin B deficiency? Here at our intravenous vitamin centre, The IV Lounge, we understand that the meaning of good health is an individual goal. Weâre here to listen to your health concerns and help you seek natural therapies; our clinic is currently accepting new patients. Book your appointment with our naturopathic doctor by emailing us at [email protected] or by calling (647) 549-3484.
The post â 5+ Reasons Why B Vitamins Are Part of IV Therapy in Toronto â was first seen on The IV Lounge.
Know more about the benefits of iv vitamin therapy and how it may help you achieve optimum health. The IV Lounge is an IV drip clinic in Toronto. Go check them out at www.theivlounge.ca
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Metabolic integration
We are down to our last topic, which is integrating everything that we have learned in the past months. This is a summary of all the pathways involved in an individual with Cancer Cachexia:
Cachexia affects the majority of patients with advanced cancer and is associated with reduced muscle strength, fatigue, appetite loss (anorexia), tissue wasting, low fat-free mass index, high levels of inflammation identified by blood tests, anemia, and low levels of the protein albumin (National Cancer Institute, 2019). Cancer patient with Cachexia are also less able to tolerate chemotherapy and other therapies they need to survive. Thus, they have a lower quality of life and worse outlook.Â
In cachexia, anaerobic glycolysis proceeds at a high rate, which forms large amounts of pyruvate and is then reduced to lactate and is exported. The lactate is then used for gluconeogenesis in the liver, an energy-requiring process, which is responsible for the hypermetabolism seen in cachexic patients. Also, in these patients, there is an increased rate of protein catabolism. The secretion of cytokines in response to cancer increase tissue protein catabolism by the ATP-dependent ubiquitin-proteasome pathway, thus, increasing energy expenditure. There is also increased stimulation of mitochondrial uncoupling proteins by cytokines, leading to thermogenesis and increased oxidation of metabolic fuels. HSL is activated by tumors, resulting in lipolysis and oxidation of fatty acids from adipose tissue (Rodwell, 2015). Moreover, cancer cells require a sufficient supply of nucleotides and other macromolecules to grow and proliferate. To meet the metabolic requirements for cell growth, cancer cells must stimulate de novo nucleotide synthesis to obtain adequate nucleotide pools to support nucleic acid and protein synthesis along with energy preservation, signaling activity, glycosylation mechanisms, and cytoskeletal function (Villa, 2019).
In relation to nutrition and exercise, muscle contraction through exercise activates and improves nutrient-induced stimulation of protein synthesis in a healthy skeletal muscle. However, disrupted mTORC1 signaling results to impaired anabolic response to contraction. Thus, cancer cachexia disrupts the metabolic and anabolic signaling response to stimulated muscle contractions and anabolic resistance to exercise is present. Given that cachexia cannot be fully reversed by conventional nutritional support. Consumption of essential amino acids such as leucine can stimulate protein synthesis in individuals. The protein synthesis induction by intaking essential amino acids may activate of mTORC1 signaling. Thus, high protein and leucine could overcome anabolic resistance in cancer cachectic individuals (Hardee, Montalvo, & Carson, 2017).Â
The major effect of cancer cachexia in the body is weight loss largely from muscles and adipose tissue. However, even though the main tissue affected by cachexia is the skeletal muscle, cachexia cannot be reduced to a muscle-wasting syndrome. Indeed, several other organs such as liver, heart, fat tissue and brain are affected, making cachexia a true multi-organ syndrome (Devlin, 2011). The effect of cancer cachexia in the different organs are the following:Â
Brain: altered pattern of hypothalamic mediators, loss of appetite, hyposmia, hypogeusia, anorexiaÂ
Brown adipose tissue: thermogenesisÂ
Heart: atrophy, decreased innervation, increased energy consumption, cardiac dysfunctionÂ
Gut: gut-barrier disfunction, altered ghrelin production, release of inflammatory mediators, malabsorptionÂ
Liver: release of acute-phase proteins, reduced albumin synthesis, acute-phase responseÂ
White adipose tissue: increased lipolysis, fatty acid oxidation, wastingÂ
Skeletal muscle: wastingÂ
Endocrine: insulin resistance, higher cortisol levels, higher BMR
References:
Devlin, T. 2011. Textbook of Biochemistry with Clinical Correlations. John Wiley & Sons, Inc.
Hardee, J. P., Montalvo, R. N., & Carson, J. A. (2017). Linking Cancer Cachexia-Induced Anabolic Resistance to Skeletal Muscle Oxidative Metabolism. Oxidative Medicine and Cellular Longevity, 2017, 1â14. doi: 10.1155/2017/8018197
Rodwell, V., et.al. 2015. Harperâs Illustrated Biochemistry 30th Edition. Copyright Š 2015 by The McGraw-Hill Education.
Tackling the Conundrum of Cachexia in Cancer. 2019. National Cancer Institute at the National Institutes of Health. Retrieved from https://www.cancer.gov/about-cancer/treatment/research/cachexia
Villa, E., Ali, E., Sahu, U. & Ben-Sahra, I. 2019. Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides. National Center for Biotechnology Information, U.S. National Library of Medicine. doi: 10.3390/cancers11050688
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Eight Signs You Might Be B12 Deficient
When you experience symptoms like fatigue, numbness, faint nausea, foggy vision or an increased tendency toward forgetfulness, you might entertain many different scenarios. Some of them might be scary, but a possibility you may not consider is that of a vitamin B12 (aka cobalamin) deficiency.
Nearly half of the American population has less-than-stellar blood levels of vitamin B12, but the symptomology is so varied that itâs hard to pin down just how many people suffer from it, according to Harvard Health, which describes the âsneakyâ symptomology behind a 62-year-old manâs seemingly unrelated symptoms, developed over two months. According to his case report, published in The New England Journal of Medicine,1 he had:
âNumbness and a âpins and needlesâ sensation in his hands, had trouble walking, experienced severe joint pain, began turning yellow, and became progressively short of breath ⌠It could have been worse â a severe vitamin B12 deficiency can lead to deep depression, paranoia and delusions, memory loss, incontinence, loss of taste and smell, and more.â2
Itâs problematic that symptoms like the above may cause people to focus on treating them instead of investigating the source of the problem. Sooner or later, though, unless itâs met head-on, a shortage of vitamin B12 in your system can be so devastating that serious disorders, such as Alzheimerâs disease, Crohn's disease and irreversible brain damage could take their toll.
Low Vitamin B12 Symptoms Not so Unrelated After All
The list of symptoms that could be placed on a B12 deficiencyâs proverbial doorstep is a long one, but many symptoms are associated with your central nervous system. Too little B12 in your system might also resonate if youâve experienced poor vision, weakness, tingling in your hands or feet and incidences of âclumsiness.â Eight common signs that indicate low B12 levels are:
Fatigue
Anemia
Nausea
Digestive issues
Weakness
Skin infections
Mental confusion
Nerve problems
But itâs also important to understand that several areas of the body can be adversely affected with a vitamin B12 deficiency, and that while many of the symptoms may seem unrelated, as the saying goes, one thing often leads to another.
Low B12 Can Cause Anemia, Which Has Its Own Set of Symptoms
As is true for every human, vitamin B12 is necessary to keep your nervous system healthy, as well as to make DNA, which is the genetic material in all cells.3 B12 is also needed to produce red blood cells, which transport oxygen throughout your body.
But with a shortage of B12, many of your red blood cells are abnormally formed and/or too large, so they canât carry oxygen; the process is disrupted. Too few red blood cells or an abnormally low amount of hemoglobin in individual red blood cells causes anemia, one of the most common and noticeable signs that a shortage is becoming a problem.4
Anemia can cause some of the previously listed symptoms, such as weakness, fatigue, dizziness, cold hands and feet, pale skin and chest pain, which occur because your heart has to work harder to move oxygen-rich blood through your body, The National Heart, Lung, and Blood Institute (NHLBI) reports.5 In turn, this can lead to irregular heartbeat or arrhythmia, enlarged heart and even heart failure.6
Recognizing B12 deficiency sooner rather than later is crucial, as left unchecked it can lead to permanent damage in your body.7 According to the Linus Pauling Institute,8 a B12 deficiency may also be culpable in several other serious diseases and conditions, including:
Breast cancer9
Chronic stomach inflammation10
Depression11
Neural tube defects12
Osteoporosis13
Gastric cancer14
Thyroid dysfunction15
DNA damage16
How Does Low B12 Cause âPins and Needles,â Jaundiced Skin and Dementia?
Because B12 â and a lack thereof â is closely associated with your nervous system, the sign known as âpins and needlesâ is one that indicates a nerve issue that should be addressed as soon as possible, and shows how interconnected your bodyâs functions are.
Because vitamin B12 is important for the maintenance of your central nervous system, including the conduction of nerve impulses and producing the myelin sheath, it protects and "insulates" your nerves. Without this protective insulation, your nerves can be damaged, leading to symptoms like âpins and needlesâ in your hands and feet, as well as central and peripheral nervous system damage.17
If youâve noticed that your skin has a pale or jaundiced cast, itâs a warning sign that your body is unable to produce an adequate number of red blood cells. You may not have thought about it, but itâs the red blood cells circulating under your skin that give it its healthy color.
Vitamin B12 deficiency can cause megaloblastic anemia, which can weaken your blood cells, after which other symptoms begin appearing. When your liver breaks down red blood cells, it releases bilirubin, a brownish substance that lends your skin a jaundiced appearance, often seen in infants.18
As if these problems werenât enough, people with low levels of B12 may also suffer problems with clear thinking, which later turns into the condition doctors call cognitive impairment or dementia.19
The symptoms often become evident when someone has reasoning difficulties and memory loss, but often, that is what is treated rather than exploring the possibility of a B12 deficiency, which could alleviate the symptoms if addressed.
An all-encompassing review in Australia in 2012 revealed associations between low vitamin B12 levels and neurodegenerative disease. A total of 43 studies revealed that âsubclinical low-normal ranges are associated with Alzheimer's disease, vascular dementia and Parkinson's disease.â20 Another study notes:
âVitamin B12 deficiency should always be looked for when a patient presents with memory loss, since it is generally reversible with treatment. Many neuropsychiatric symptoms have been observed, and many in patients who do not have a megaloblastic anemia.
These include memory loss, psychosis including hallucinations and delusions, fatigue, irritability, depression and personality changes.â21
A B12 Deficiency Often Shows Up in Your Mouth
One symptom of anemia that often shows up are mouth ulcers, sometimes known as canker sores or aphthous ulcers, small yellow or white ulcers that can appear on your gums or just inside your lip. While they usually clear up in a week or two, theyâre often quite painful.
But a B12 deficiency can cause other symptoms in your mouth as well, including on your tongue. One study relates the experience of a middle-aged female patient â a common demographic for her symptoms â with a persistent burning sensation on her tongue for several months.
Diagnosed with glossitis, which causes a noticeably swollen, smooth, red tongue, she was given a single injection of vitamin B12, which âresulted in complete resolution of her symptoms and the normal clinical appearance of her tongue after three days.â22
Low B12 Carries Increased Risk for Infection by Two Potentially Deadly Pathogens
People with deficiency in vitamin B12 are at a higher risk of infections caused by two potentially deadly pathogens. Findings of a study published in the journal PLOS Genetics23 involved 1 millimeter-long (pencil tip-sized) nematodes or worms called Caenorhabditis elegans (C. elegans), one of the worldâs most basic organisms.
Vital to the study was that nematodes share an interesting characteristic with humans: They canât produce their own vitamin B12, either. As reported by MedIndia, the study involved two worm populations: one with and one without a diet sufficient in B12, showing that a B12-deficient diet harms the wormâs health at a cellular level by reducing its ability to metabolize branched-chain amino acids (BCAA):
âThe research showed that the reduced ability to break down BCAAs led to a toxic buildup of partially metabolized BCAA byproducts that damaged mitochondrial health ⌠âWe used C. elegans to study the effect of diet on a host and found that one kind of food was able to dramatically increase resistance to multiple stressors â like heat and free radicals â as well as to pathogens,â said [researcher Natasha Kirienko].â24
Many labs around the world use C. elegans to study the effects of disease. By feeding the worms E. coli, a common and sometimes harmful gut bacteria, and switching between E. coli strain OP50 and strain HT115, the wormsâ stress tolerance was âdramatically altered,â Kirienko said. âWe found that switching between E. coli strain OP50 and strain HT115 dramatically altered the worm's stress tolerance.â Co-author Alexey Revtovich noted:
âThe key difference between the two diets is the ability of HT115 and OP50 to acquire B12 from the environment ⌠We showed that HT115 is far more efficient at this, making about eight times as much of the protein that it needs to harvest B12 as compared to OP50.â25
Significantly, the team also found that C. elegans on an HT115 diet had the ability to resist infection by another deadly human pathogen, Enterococcus faecalis, a leading cause of hospital-acquired infections and recognized by the World Health Organization and U.S. Centers for Disease Control and Prevention (CDC) as a superbug.26
Kirienko noted that the B12 finding surprised the research team. They noticed the effect when they studied âthe mechanisms of pathogenesis of Pseudomonas aeruginosa (P. aeruginosa), a potentially deadly disease in both worms and humans that infects some 51,000 U.S. hospital patients each year,â27 according to the CDC.28
Higher Risks and How to Optimize Your Vitamin B12 Levels
Some people have a greater risk than others for vitamin or mineral deficiencies, but in this case vegans and vegetarians are at particular risk because B12 is derived from animal products. Additionally, older adults and people with gastrointestinal and malabsorption issues are also at risk.
Studies have also shown that those on metformin (for diabetes) and prolonged use of proton pump inhibitors (for stomach acid) are also at an increased risk for vitamin B12 deficiency, leading researchers to suggest âit seems prudent to monitor vitamin B12 levels periodically in patients taking metformin.â29
Because itâs not manufactured by your body, vitamin B12 must come from another source â namely food and supplements. That said, good sources for cobalamin or vitamin B12 include:
Grass fed organic beef and beef liver
Lamb
Venison
Scallops
Organic, pastured chicken and eggs
Raw organic, grass fed milk
Nutritional yeast
As for supplementation, according to the National Institutes of Health (NIH),30 the average person age 14 and older should get 2.4 micrograms (mcg â one-millionth of a gram31) of vitamin B12 per day; pregnant women should get 2.6 mcg; and breastfeeding women should get 2.8 mcg. Newborns and children up to age 13 require between 0.4 and 1.8 mcg.
The type of a vitamin B12 supplement you should take is also something to consider. Between cyanocobalamin, the synthetic form,32 and methylcobalamin, which is the naturally occurring form found in food, methylcobalamin is the better choice, one reason being that your body retains it in greater amounts.33
from http://articles.mercola.com/sites/articles/archive/2019/03/25/signs-of-vitamin-b12-deficiency.aspx
source http://niapurenaturecom.weebly.com/blog/eight-signs-you-might-be-b12-deficient
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Eight Signs You Might Be B12 Deficient
When you experience symptoms like fatigue, numbness, faint nausea, foggy vision or an increased tendency toward forgetfulness, you might entertain many different scenarios. Some of them might be scary, but a possibility you may not consider is that of a vitamin B12 (aka cobalamin) deficiency.
Nearly half of the American population has less-than-stellar blood levels of vitamin B12, but the symptomology is so varied that itâs hard to pin down just how many people suffer from it, according to Harvard Health, which describes the âsneakyâ symptomology behind a 62-year-old manâs seemingly unrelated symptoms, developed over two months. According to his case report, published in The New England Journal of Medicine,1 he had:
âNumbness and a âpins and needlesâ sensation in his hands, had trouble walking, experienced severe joint pain, began turning yellow, and became progressively short of breath ⌠It could have been worse â a severe vitamin B12 deficiency can lead to deep depression, paranoia and delusions, memory loss, incontinence, loss of taste and smell, and more.â2
Itâs problematic that symptoms like the above may cause people to focus on treating them instead of investigating the source of the problem. Sooner or later, though, unless itâs met head-on, a shortage of vitamin B12 in your system can be so devastating that serious disorders, such as Alzheimerâs disease, Crohnâs disease and irreversible brain damage could take their toll.
Low Vitamin B12 Symptoms Not so Unrelated After All
The list of symptoms that could be placed on a B12 deficiencyâs proverbial doorstep is a long one, but many symptoms are associated with your central nervous system. Too little B12 in your system might also resonate if youâve experienced poor vision, weakness, tingling in your hands or feet and incidences of âclumsiness.â Eight common signs that indicate low B12 levels are:
Fatigue
Anemia
Nausea
Digestive issues
Weakness
Skin infections
Mental confusion
Nerve problems
But itâs also important to understand that several areas of the body can be adversely affected with a vitamin B12 deficiency, and that while many of the symptoms may seem unrelated, as the saying goes, one thing often leads to another.
Low B12 Can Cause Anemia, Which Has Its Own Set of Symptoms
As is true for every human, vitamin B12 is necessary to keep your nervous system healthy, as well as to make DNA, which is the genetic material in all cells.3 B12 is also needed to produce red blood cells, which transport oxygen throughout your body.
But with a shortage of B12, many of your red blood cells are abnormally formed and/or too large, so they canât carry oxygen; the process is disrupted. Too few red blood cells or an abnormally low amount of hemoglobin in individual red blood cells causes anemia, one of the most common and noticeable signs that a shortage is becoming a problem.4
Anemia can cause some of the previously listed symptoms, such as weakness, fatigue, dizziness, cold hands and feet, pale skin and chest pain, which occur because your heart has to work harder to move oxygen-rich blood through your body, The National Heart, Lung, and Blood Institute (NHLBI) reports.5 In turn, this can lead to irregular heartbeat or arrhythmia, enlarged heart and even heart failure.6
Recognizing B12 deficiency sooner rather than later is crucial, as left unchecked it can lead to permanent damage in your body.7 According to the Linus Pauling Institute,8 a B12 deficiency may also be culpable in several other serious diseases and conditions, including:
Breast cancer9
Chronic stomach inflammation10
Depression11
Neural tube defects12
Osteoporosis13
Gastric cancer14
Thyroid dysfunction15
DNA damage16
How Does Low B12 Cause âPins and Needles,â Jaundiced Skin and Dementia?
Because B12 â and a lack thereof â is closely associated with your nervous system, the sign known as âpins and needlesâ is one that indicates a nerve issue that should be addressed as soon as possible, and shows how interconnected your bodyâs functions are.
Because vitamin B12 is important for the maintenance of your central nervous system, including the conduction of nerve impulses and producing the myelin sheath, it protects and âinsulatesâ your nerves. Without this protective insulation, your nerves can be damaged, leading to symptoms like âpins and needlesâ in your hands and feet, as well as central and peripheral nervous system damage.17
If youâve noticed that your skin has a pale or jaundiced cast, itâs a warning sign that your body is unable to produce an adequate number of red blood cells. You may not have thought about it, but itâs the red blood cells circulating under your skin that give it its healthy color.
Vitamin B12 deficiency can cause megaloblastic anemia, which can weaken your blood cells, after which other symptoms begin appearing. When your liver breaks down red blood cells, it releases bilirubin, a brownish substance that lends your skin a jaundiced appearance, often seen in infants.18
As if these problems werenât enough, people with low levels of B12 may also suffer problems with clear thinking, which later turns into the condition doctors call cognitive impairment or dementia.19
The symptoms often become evident when someone has reasoning difficulties and memory loss, but often, that is what is treated rather than exploring the possibility of a B12 deficiency, which could alleviate the symptoms if addressed.
An all-encompassing review in Australia in 2012 revealed associations between low vitamin B12 levels and neurodegenerative disease. A total of 43 studies revealed that âsubclinical low-normal ranges are associated with Alzheimerâs disease, vascular dementia and Parkinsonâs disease.â20 Another study notes:
âVitamin B12 deficiency should always be looked for when a patient presents with memory loss, since it is generally reversible with treatment. Many neuropsychiatric symptoms have been observed, and many in patients who do not have a megaloblastic anemia.
These include memory loss, psychosis including hallucinations and delusions, fatigue, irritability, depression and personality changes.â21
A B12 Deficiency Often Shows Up in Your Mouth
One symptom of anemia that often shows up are mouth ulcers, sometimes known as canker sores or aphthous ulcers, small yellow or white ulcers that can appear on your gums or just inside your lip. While they usually clear up in a week or two, theyâre often quite painful.
But a B12 deficiency can cause other symptoms in your mouth as well, including on your tongue. One study relates the experience of a middle-aged female patient â a common demographic for her symptoms â with a persistent burning sensation on her tongue for several months.
Diagnosed with glossitis, which causes a noticeably swollen, smooth, red tongue, she was given a single injection of vitamin B12, which âresulted in complete resolution of her symptoms and the normal clinical appearance of her tongue after three days.â22
Low B12 Carries Increased Risk for Infection by Two Potentially Deadly Pathogens
People with deficiency in vitamin B12 are at a higher risk of infections caused by two potentially deadly pathogens. Findings of a study published in the journal PLOS Genetics23 involved 1 millimeter-long (pencil tip-sized) nematodes or worms called Caenorhabditis elegans (C. elegans), one of the worldâs most basic organisms.
Vital to the study was that nematodes share an interesting characteristic with humans: They canât produce their own vitamin B12, either. As reported by MedIndia, the study involved two worm populations: one with and one without a diet sufficient in B12, showing that a B12-deficient diet harms the wormâs health at a cellular level by reducing its ability to metabolize branched-chain amino acids (BCAA):
âThe research showed that the reduced ability to break down BCAAs led to a toxic buildup of partially metabolized BCAA byproducts that damaged mitochondrial health ⌠âWe used C. elegans to study the effect of diet on a host and found that one kind of food was able to dramatically increase resistance to multiple stressors â like heat and free radicals â as well as to pathogens,â said [researcher Natasha Kirienko].â24
Many labs around the world use C. elegans to study the effects of disease. By feeding the worms E. coli, a common and sometimes harmful gut bacteria, and switching between E. coli strain OP50 and strain HT115, the wormsâ stress tolerance was âdramatically altered,â Kirienko said. âWe found that switching between E. coli strain OP50 and strain HT115 dramatically altered the wormâs stress tolerance.â Co-author Alexey Revtovich noted:
âThe key difference between the two diets is the ability of HT115 and OP50 to acquire B12 from the environment ⌠We showed that HT115 is far more efficient at this, making about eight times as much of the protein that it needs to harvest B12 as compared to OP50.â25
Significantly, the team also found that C. elegans on an HT115 diet had the ability to resist infection by another deadly human pathogen, Enterococcus faecalis, a leading cause of hospital-acquired infections and recognized by the World Health Organization and U.S. Centers for Disease Control and Prevention (CDC) as a superbug.26
Kirienko noted that the B12 finding surprised the research team. They noticed the effect when they studied âthe mechanisms of pathogenesis of Pseudomonas aeruginosa (P. aeruginosa), a potentially deadly disease in both worms and humans that infects some 51,000 U.S. hospital patients each year,â27 according to the CDC.28
Higher Risks and How to Optimize Your Vitamin B12 Levels
Some people have a greater risk than others for vitamin or mineral deficiencies, but in this case vegans and vegetarians are at particular risk because B12 is derived from animal products. Additionally, older adults and people with gastrointestinal and malabsorption issues are also at risk.
Studies have also shown that those on metformin (for diabetes) and prolonged use of proton pump inhibitors (for stomach acid) are also at an increased risk for vitamin B12 deficiency, leading researchers to suggest âit seems prudent to monitor vitamin B12 levels periodically in patients taking metformin.â29
Because itâs not manufactured by your body, vitamin B12 must come from another source â namely food and supplements. That said, good sources for cobalamin or vitamin B12 include:
Grass fed organic beef and beef liver
Lamb
Venison
Scallops
Organic, pastured chicken and eggs
Raw organic, grass fed milk
Nutritional yeast
As for supplementation, according to the National Institutes of Health (NIH),30 the average person age 14 and older should get 2.4 micrograms (mcg â one-millionth of a gram31) of vitamin B12 per day; pregnant women should get 2.6 mcg; and breastfeeding women should get 2.8 mcg. Newborns and children up to age 13 require between 0.4 and 1.8 mcg.
The type of a vitamin B12 supplement you should take is also something to consider. Between cyanocobalamin, the synthetic form,32 and methylcobalamin, which is the naturally occurring form found in food, methylcobalamin is the better choice, one reason being that your body retains it in greater amounts.33
from Articles http://articles.mercola.com/sites/articles/archive/2019/03/25/signs-of-vitamin-b12-deficiency.aspx source https://niapurenaturecom.tumblr.com/post/183691115831
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The Dark Side of Metformin (Plus Natural, Safe & Healthy Methods I Use To Regulate My Blood Sugar).
In the recent Wired magazine article âForget The Blood Of Teens. This Pill Promises To Extend Life For A Nickel A Pop,â it is reported how Tim Ferriss, in his recent book Tools of Titans, estimates that at least a dozen of the billionaires, icons, and world-class performers in the book take metformin.
Robert Hariri, a member of the anti-aging panel at the Vatican and co-founder and president of genetic sequencing pioneer Craig Venterâs Human Longevity Cellular Therapeutics and Ray Kurzweil, of Singularity fame, along with Ned David, co-founder of Silicon Valley startup Unity Biotechnology (which is developing its own anti-aging drugs) all also take metformin.
In fact, metformin (along with rapamycin, which I will write an article on in the near future) is now considered to be one of the new darlings of the anti-aging industry and is widely used among CEOs, Silicon Valley, many of my friends in the anti-aging industry and beyond.
So whatâs my beef with this supposed wonder-drug?
It turns out that there are all kinds of potential problems with metformin. In recent years, evidence has accumulated that metformin may not be all its cracked up to be. Or at least, even if it does what it claims to do, it has a number of adverse side effects. But up until now, pharmaceutical companies have somewhat sugar-coated the drugâs effects.
In this article, Iâll briefly highlight why I donât personally take metformin. Iâll also introduce you to natural compounds that I personally use to regulate my blood sugar.Â
Is Metformin Healthy?
Metformin falls into a category of a biguanide molecule. Biguanides are derivatives of guanidine, a naturally occurring substance found in vegetables such as turnips and cereals. They exert a blood glucose-lowering effect in type 2 (non-insulin dependent) diabetes mellitus, and since they do not increase plasma insulin concentrations and do not cause hypoglycemia (unless, as noted below, combined with exercise), they are generally regarded as antihyperglycemic (rather than hypoglycemic) agents.
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But one of the problems with these type of molecules is that they can increase the generation of lactate, which then enters the circulation and produces lactic acidosis.
The study âFatty acids revert the inhibition of respiration caused by the antidiabetic drug metformin to facilitate their mitochondrial β-oxidationâ describes quite clearly this metformin effect on lactate production. But before getting into that, a quick note on phenformin. Phenformin is another member of the biguanide family and was a popular medication for diabetes starting in the 1950s. It was withdrawn from clinical use in the 1970s once it was discovered that it caused severe lactic acidosis. Although phenformin is associated with a 10- to 20-fold greater incidence of lactic acidosis than its relative metformin, metforminâs effects on acidosis are still significant enough in my opinion not to be ignored (especially if youâre an athlete who is already flirting regularly with acidosis â although admittedly Iâve seen little performance data on metforminâs effect on lactic acid formation during exercise).
Furthermore, despite being the most commonly prescribed drug for the treatment of type II diabetes for more than five decades, the bioenergetic mechanisms underlying metformin activity remain largely unknown. This ignorance of the inner workings of the drug has triggered many endeavors to uncover how exactly it works â but the results are often contradictory. The study âCardiovascular and metabolic effects of metformin in patients with type 1 diabetes: a double-blind, randomized, placebo-controlled trialâ found that while metformin may play a very wide role in managing cardiovascular risks, it doesnât necessarily improve glycemia, and it had no average effect on insulin requirement. In fact, while there were two deaths in the placebo group, there were five among the patients allocated to metformin.
But cardiovascular risk management also falls under scrutiny under certain conditions. True, metformin may be beneficial when used on its own. But, according to the study âReappraisal of Metformin Efficacy in the Treatment of Type 2 Diabetes,â when combined with sulphonylurea (another common antidiabetic medication), metformin can actually result in an increased risk of cardiovascular complications and all-cause mortality. Studies are inconclusive at the time being, but the drug has been shown to have no proven efficacy against microvascular complications. Indeed, the possibility that metformin is not effective at all shouldnât be dismissed out of hand. After all, the first molecule of this type, phenformin, did induce cardiovascular risk, and, pharmacologically speaking, thereâs little difference between phenformin and metformin.
All that to say, the specific efficacy of metformin to prevent death or cardiovascular disease has not been proven beyond reasonable doubt by current studies. So metformin may not be the best comparator for evaluating hypoglycemic drugs â and thatâs not even the end of the story.
Metformin can also cause a deficiency of vitamin B12 levels. The study âLong term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiencyâ observed this effect. While the drug did cause reported improvements in cardiovascular morbidity and mortality (but, as youâve seen, thatâs already been called into question), it stimulated vitamin B12 malabsorption.
Decreased B-12 concentrations can cause increased homocysteine concentrations, which is, surprise, an independent risk factor for cardiovascular disease, particularly among individuals with type 2 diabetes. During the 52 months of the study, the placebo group experienced an increase in vitamin B-12 concentrations, while the metformin group experienced an average 19% decrease in B12 concentrations, a decrease which continues to grow over time. While the lower B12 concentrations were not a novel idea, the progressive nature was â they can result in macrocytic anemia, neuropathy, and mental changes, potentially making metformin a dangerous treatment to use.
Another study, âMetformin and Exercise in Type 2 Diabetes,â determined the effects of metformin on the metabolic response to submaximal exercise, the effect of exercise (relevant to activity patterns of type 2 diabetics) on plasma metformin concentrations, and the interaction between metformin and exercise on the response to a standardized meal. There is evidence that suggests that the benefits of exercise and metformin arenât cumulative. In a study whose results were noted in this one, the reductions in diabetic risk were similar in a lifestyle that combined metformin and lifestyle modifications to the metformin or lifestyle alone groups.
In fact, the two adjustments may have contradictory effects on diabetes. First, metformin reduces blood glucose levels. But exercise tends to increase levels of glucagon, the hormone that deals with low blood sugar. When the two are combined, glucagon concentrations become significantly higher as the body tries to compensate for the effect of metformin. Second, by increasing the heart rate, metformin has the potential to lower some patientsâ selected exercise intensity, which means it could lead to the prescription of lower exercise workloads than are commonly recommended.
So, the combination of exercise and metformin, both common prescriptions for diabetics, is likely less effective at lowering the glycemic response to a meal than metformin alone. There have also been studies out of Taiwan showing that metformin taken by diabetics for long periods of time (12 years or longer) can nearly double the risk of Alzheimerâs and Parkinsonâs.
There have even been a handful of reports of metformin-induced hepatotoxicity (toxicity in the liver). In a case of nonalcoholic liver disease, metformin was pegged as the cause of jaundice, nausea, fatigue, and unintentional weight loss, two weeks after initiating treatment, due to abnormalities in liver enzymes caused by the drug. Another case involved a 73-year old Japanese woman who experienced fatigue, jaundice, nausea, vomiting, anorexia, and abdominal pain due to severe hepatotoxicity that resulted from metformin.
I recently asked Dr. Dallas Clouatre, a well-established author and consultant in the alternative and complementary medicine and nutrition field and my guest on the podcast episode How Low-Fat Diets Make You Fat, about his thoughts on metformin, and hereâs what he had to say:
âMy thoughts on metformin are that it is interesting but over-hyped. Keep in mind that it works primarily on the liver (30% of glucose clearance from meals) and not on the peripheral tissues (70% of glucose clearance). It likely does promote a longer âhealth spanâ given that lowering insulin and IGF-1 along with mTOR, typical of caloric restriction and of those who naturally live to extreme old age, is usually a good thing. Of course, any item that keeps insulin levels low along with keeping blood glucose in the low-normal range will lower mTOR. Downsides of metformin include reduced efficacy with advancing age, reduced efficacy with prolonged use, and GI-tract issues in some individuals. Given that rehabilitation of the mitochondrial electron transport Complex I is a normal function of a good nightâs sleep, for me, it is difficult to suggest the chronic intake of a drug that works by gumming up a natural process of the body.â
So Where Does This All Leave Metformin?
Despite the 20 years of positive clinical observations on metformin, these recent studies and the information above, in my opinion, have called its efficacy and overall health benefits into question.
Perhaps itâs time to broaden the horizons and look to natural alternatives that can have very similar antidiabetic, blood sugar stabilizing and longevity-enhancing effects, including many of the natural strategies and compounds I discuss in my articles âHow To Biohack Your Blood Sugar Levelsâ and â5 Simple Steps You Can Take To Live Longer, Banish Blood Sugar Swings & Massively Enhance Energy Levels.â, including:
So that you can equip your cupboard with compounds that can safely and naturally support your blood sugar levels, Iâd like to expound on that last category of plants, herbs and spices.
Letâs begin with Ceylon cinnamon. Cinnamon has a long history both as a spice and as a medicine, and itâs unique healing abilities come from the essential oils found in its bark, which contain three active components called cinnamaldehyde, cinnamyl acetate, and cinnamyl alcohol. The cinnamaldehyde in cinnamon helps prevent unwanted clumping of blood platelets, which makes cinnamon anti-inflammatory.
In one study, the antioxidant effects of a cinnamon extract in people with prediabetes decreased a marker of oxidative stress by fourteen percent. Participants took 250 mg of cinnamon extract, twice per day, for twelve weeks. This is significant considering that chronic inflammation and oxidative stress plays a role in nearly every chronic disease, including diabetes.
Cinnamon also mimics the effects of insulin, which increases insulin sensitivity, making insulin more efficient at shuttling glucose into cells. Five grams of cinnamon is all you need to do this while also reducing total plasma glucose response. Effects last twelve hours. Cinnamon also reduces fasting blood glucose, total cholesterol, and triglycerides, and it increases HDL cholesterol. And the best type of cinnamon to use? Approximately the equivalent of 2 teaspoons of organic Ceylon cinnamon per day will suffice (it is important that the cinnamon is indeed of the Ceylon variety). I like to buy it in bulk.
Gymnema Sylvestre is another potent herbal tactic for controlling glycemic variability. It has been used in traditional Ayurvedic medicine for thousands of years and has promising research around its ability to control blood sugar levels. Its blood sugar lowering effects are possibly due to it causing an increase in insulin secretion, which partially explains its ability to increase glucose utilization, with this also being due to it increasing the activities of enzymes responsible for utilization of glucose by insulin-dependant pathways. The increase in insulin secretion may be explained by Gymnema supplementation regenerating pancreatic islet beta cells, the cells responsible for sensing sugar in the blood and telling the pancreas to release the proper amount of insulin to maintain normal blood sugar levels. Gymnema also inhibits glucose absorption from the intestines and has been shown to lower serum cholesterol and triglycerides.
Gymnema Sylvestre extract administered to non-insulin-dependant type 2 diabetics at 400 mg per day for 18 months significantly reduced blood sugar, hemoglobin A1c and glycosylated plasma protein levels, with many participants lowering their diabetes medication and five participants ending with controlling blood sugar using Gymnema Sylvestre extract alone. The same reductions have occurred in people with type 1 diabetes, with Gymnema also allowing for a decrease in insulin requirements. The easiest way to use Gymnema Sylvestre is by taking one 400-600 mg capsule, standardized to contain 25 percent gymnemic acid, ten minutes before a carbohydrate containing meal.
Berberine, a compound derived from a variety of herbs including goldenseal and Oregon grape root, shows a variety of distinct benefits. It increases glucose uptake by the cells and improves insulin utilization by increasing glucose uptake pathways GLUT-4 and GLUT-1. Berberine also activates AMP-activated protein kinase (AMPK), with increased activation allowing for a reduction in fat storage, increased insulin sensitivity, reduction in cholesterol/triglyceride production, and suppression of chronic inflammation.
Berberine has also been shown to significantly reduce free fatty acids, high levels of which damage the pancreas and insulin production In one study, berberine significantly lowered fasting blood glucose, hemoglobin A(1c), triglyceride, and insulin levels in type 2 diabetics by increasing insulin receptor expression. It also improved liver function. Another study found that 500 mg of berberine taken twice per day by patients with type 2 diabetes lowered blood glucose, fasting insulin, and blood lipid levels and it was as effective at lowering blood glucose as metformin.
Thereâs a ton more research you can read here on berberine on everything from metabolic syndrome, PCOS, osteoporosis and much more. The standard dose of berberine HCL is 900-2,000mg a day, divided into three to four doses, taken with a meal.
The Two Compounds I Personally Use Daily To Regulate Blood Sugar
Since beginning to test my blood glucose continuously using a Dexcom G6 implanted in my abdomen (as I describe in detail in my last post on how to track ketones and glucose), Iâve experimented with taking THREE servings of Kion Lean each day. Iâm taking two capsules before every meal, three times per day.
I realize six capsules a day is a lot, but I may actually continue this as a staple in my life extension and weight management protocol, and Iâd highly recommend you try it, especially if you want to support your blood sugar levels.Â
You can get it here and read up on the ingredients, but Iâm going to elucidate below.
It begins with the story of the people who inhabit the western region of China on the slopes of the Himalayas â Bama County. This place is famous for the longevity of its inhabitants. In the year 2000, there were at least 79 men and women over one hundred years old, and still in good health, among a population of fewer than 230,000 people. Thatâs 3.52 centenarians per ten thousand people, the highest concentration anywhere in the world.
The residents and some medical researchers attribute their long lives to a plant known locally as âshilianhuaâ, and known in English as the ârock lotusâ or the âstone lotusâ. For hundreds of years, itâs been used both as food and as a medicinal herb in the Bama region to treat a variety of conditions. And it has massive longevity benefits.
Only two mechanisms have been shown to be successful in promoting longevity, like that of the Bama region people, in higher organisms. The first lowers the levels of insulin and insulin-like growth factor 1. The second restricts calories, which usually has, as one result, a reduction of circulating insulin levels. The rock lotus influences both of these mechanisms. Itâs been found that rock lotus can reduce blood sugar levels by up to 30%, helping people in China and elsewhere to take their health into their own hands.
So rock lotus is the first herb I use daily, in the form of Kion Lean. Another similar wild plant is bitter melon, also known as âgoyaâ in Japan, and also found in Kion Lean, which Iâve been using it to manage my postprandial blood glucose levels with potent efficacy for the past four years.
Bitter melon has only positives, as far as I am concerned. Itâs fresh on my mind, because like I mentioned, when I was in New York City, I had the pleasure of spending quite a bit of time with Chef David Bouley, a world-famous Japanese cuisine expert who frequently travels to Asia to study specific food consumption and dietary habits that allow locales such as Okinawa, Japan to be such longevity hotspots. And one of the large bags of tea he brought back with him and gave to me was comprised of the same compound they ate in copious quantities before nearly every meal â you guessed it â bitter melon extract.
Although the precise mechanism by which it works (whether itâs through regulation of insulin release or altered glucose metabolism and its insulin-like effect) is not known, bitter melon naturally contains compounds like charantin, vicine, and polypeptide-p, plus some other health-boosting components like antioxidants.
Bitter melon is a popular blood sugar supporting supplement among the indigenous people of Asia, South America, India, and East Africa. As noted earlier, itâs known particularly well in Okinawa, Japan. Okinawa, like the Bama County, is one of the worldâs âblue zonesâ, an area where the average lifespan is unusually long, and itâs also where some of the longest-lived people on the planet live.
In places like Okinawa, almost every part of the bitter melon has been used in traditional medicine, including the fruit, leaves, vines, seeds, and roots. Itâs been used in traditional Okinawan medicine to treat everything from microbial infections to digestive issues, stimulate menstruation, heal wounds, reduce inflammation and fevers, deal with hypertension, and itâs even been used as a laxative and emetic. It also activates cellular machinery to regulate energy production (particularly AMP-activated protein kinase) and the way fats are processed by the liver.
Centuries of oral consumption have demonstrated that bitter melon is both safe and effective. And on top of all those other conditions, according to a number of animal studies, it can even reduce insulin resistance and protect against diet-induced hyperglycemia and hyperinsulinemia.
It should be noted, though, that commercially-sold varietals are not nearly as effective as wild bitter melon. One study observed the effects of bitter melon on rats. Specifically, they used an aqueous extract powder of fresh, unripe melons, and found that a dose of 20 mg per kilogram of body weight reduced fasting blood glucose levels by 48%. That rivals the effects of another popular synthetic medication, glibenclamide. And, compared to synthetic drugs like glibenclamide and metformin, the melon doesnât show any kind of hepatotoxicity or nephrotoxicity (toxicity in the kidneys).
Part of the reason bitter melon is so darn effective is likely its effect on GLP-1 secretion. GLP-1 is glucagon-like peptide-1, a peptide released from what are called L-cells, which increase in density along the length of the intestines. It helps to raise insulin levels as a part of the incretin effect, a hormonal response that effects insulin secretion following oral glucose ingestion. A study was done to examine the role of bitter melon extract in this process and found that through bitter taste receptors and/or a PLC β 2-signaling pathway, the melon stimulated GLP-1 release.
Now, before you think that by supplementing your diet with bitter melon, your insulin levels will get too high, itâs important to note that insulin levels that are regulated by GLP-1 are either reduced or, in some cases, completely absent in people suffering from diabetes. Considering that, and the fact that GLP-1 has an extremely short half-life due to rapid inactivation, itâs not likely that your insulin levels will become abnormally high by using the melon. In all likeliness, your insulin count will rise and settle at a relatively normal level. However, further studies will need to be performed to confirm this.
And thereâs more.
Bitter melon, specifically a wild species called Momordica charantia Linn var. abbreviata ser., can also regulate lipopolysaccharide (LPS)-induced inflammatory responses. Wild bitter melon and bitter melon extracts were used in a study to inhibit macrophage activity, which is a part of your natural immunological response to stress, disease, and tears in body tissues. The LPS-stimulated macrophages that were targeted responded to both extracts, but especially to the wild variety of the melon, resulting in much-reduced LPS-induced inflammation.
As you may already know, insulin resistance is closely related to chronic inflammation induced by things like tumor necrosis factor-Îą (TNF- Îą), a compound that seeks out and destroys cancerous cells. But before jumping into the importance of TNF- Îą, you should memorize this chemical: triterpene 5β, 19-epoxy-25-methoxy-cucurbita-6.23-diene-3β, 19-diol â or, for short, EMCD. Itâs purified from a wild species of bitter melon that was thought to activate AMP-activated protein kinase (AMPK), which itself is thought to repress TNF- Îą-induced inflammation.
When it was tested alongside a compound extracted from green tea thatâs also reported to be anti-inflammatory, EMCD showed more obvious anti-inflammatory activity, but not by activating AMPK. It actually inhibited the activation of the IkB kinase, an important aspect of pro-inflammatory signaling. Since inflammation is connected to shorter lifespans and greater risk of conditions like cardiovascular diseases, it would be wise to look into taking necessary precautions to minimize inflammation.
Want more interesting reading on bitter melon extract? Check out these links:
So what do the rock lotus and wild bitter melon have in common that promote fat burning, liver health (and of course, anti-aging)? The answer involves caloric restriction and insulin.
As youâve just learned, two basic mechanisms have been shown to be successful in promoting longevity in higher organisms. The first mechanism lowers the levels of insulin and insulin-like growth factor 1 (IGF-1). The second mechanism restricts calories, which usually has, as one result, a lowering of circulating insulin levels. Rock lotus influences both of these mechanisms. According to a Jutendo Medical University of Japan clinical trial, rock lotus improves liver function and fatty liver. This action resembles that of compounds known to reduce insulin levels as an aspect of improved blood glucose control.
Wild bitter melon is similarly health promoting. For example, it has been found that extracts of the wild bitter melon activate cellular machinery to regulate energy production (technically AMPK-activated protein kinase) and the way that fats are handled by the liver. Activation of this metabolic pathway is important to aging. It is sometimes referred to as âexercise in a bottleâ because activation of AMPK is an aspect of the benefits derived from exercise. The effect of an extract from the wild genotype of bitter melon called GlycostatÂŽ has proved to be more powerful than others on the market and much more consistent in producing positive results.
In short, rock lotus and bitter melon extract work better in combination than their isolated components. Both promote better blood sugar support with less insulin. Both promote healthy blood pressure. Both support healthy liver function. And both mimic changes in cellular energy metabolism typical of caloric restriction.
Summary
So in summary, Iâm not a huge fan of metformin, but I am a huge fan of strength training and physical activity to manage blood sugar levels for both health and longevity. For regulating my blood sugar levels, I personally consider bitter melon extract, especially when combined with rock lotus, to be at the top of my list.
In tandem, for me personally and based on my own continuous blood glucose testing levels I discuss in my article âThe Best Way To Test For Ketosis & Track Your Blood Glucoseâ, the combination of bitter melon with rock lotus works like gang-busters to regulate blood sugar levels after my evening carbohydrate-laden meal â and with more frequent dosing at three times per day is keeping my daily average blood sugar levels in the 70-89 range consistently. All my clients already pop two capsules of Kion Lean â a concentrated source of bitter melon and rock lotus â prior to any carbohydrate-rich meal, and I do too, for the past four years. It just works.
Do you have questions, thoughts or feedback for me about metformin or managing blood sugar? Leave your comments below and I will reply!
Ask Ben a Podcast Question
Source: https://bengreenfieldfitness.com/article/supplements-articles/dark-side-metformin/
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What Happens to Your Body When You Eat Gluten?
The word âglutenâ has become such a buzzword in recent years, most likely because of the sudden popularity of the gluten-free diet thatâs been endorsed by famous personalities. Before you consider trying this diet, read this page first to learn about gluten, and how it can negatively impact your body and health in the long run.
What Is Gluten?
A type of protein, gluten is composed of glutenin and gliadin molecules that form an elastic bond when mixed with water. Gluten is highly noted for its adhesive abilities that can maintain a compact structure for holding bread and cakes together, and providing a spongier texture. This ability isnât surprising, considering that the word âglutenâ is derived from the Latin word for âglue.â
While it does wonders for these foods, the same cannot be said for your body. Research has shown that gluten can be quite harmful for you because of the vast range of complications it might cause (more on this to come in a while).
What Does Gluten Do to Your Body?
A major caveat linked to gluten is its tendency to impede proper nutrient breakdown and absorption from foods, regardless if they have gluten or not. This may prevent proper digestion because excess gluten leads to the formation of a glued-together constipating lump in the gut. Afterward, the undigested gluten prompts the immune system to attack the villi, or the fingerlike projections lining your small intestine.1 This may lead to side effects such as  diarrhea or constipation, nausea and abdominal pain.
Excessive gluten consumption and further small intestine damage and inflammation may predispose a person to nutrient malabsorption, nutrient deficiencies, anemia, osteoporosis, other neurological or psychological diseases, and complications linked to the skin, liver, joints, nervous system and more.
What Are the Types of Food That Contain Gluten?
Gluten is predominantly found in whole grains like rye, barley, triticale and oats; in wheat varieties like spelt, kamut, farro, durum; and in other products like bulgar and semolina.2 Wheat-based flours and byproducts that also contain high quantities of this protein include:3,4,5,6
Wheat-Based Flours Wheat Byproducts
⢠White flour
⢠Whole wheat flour
⢠Graham flour
⢠Triticale
⢠Wheat germ
⢠Wheat bran
⢠Pasta
⢠Couscous
⢠Bread, bread crumbs and croutons
⢠Flour tortillas
⢠Cookies, cakes, muffins and pastries
⢠Cereal
⢠Crackers
⢠Beer
⢠Gravy, dressings and sauces
⢠Conventional oats (these have a high chance of being contaminated during the growing, harvesting or processing stages
If thereâs another compelling reason why you shouldnât eat processed foods, itâs because these items often contain gluten. Here are examples of foods with gluten, even though theyâre not made from grains:7,8
Processed broth and bouillon cubes9
 Fried foods
 Candies
 Lunch meats and hot dogs
Cold cuts
Dumplings
Self-basting poultry
Crab cakes
Imitation fish
Seasoned rice10
Matzo
Modified food starch11
Salad dressings
Seasoned chips and other seasoned snack foods
Processed yogurt12
Ice cream cones
Even worse, manufacturers deceive customers by âhidingâ gluten products like wheat under other names in food labels, such as:13,14
⢠Malts
⢠Starches and other derivatives
⢠Hydrolyzed vegetable protein (HVP)
⢠Hydrolyzed wheat protein15
⢠Textured vegetable protein (TVP)
Common Signs of a âGluten Allergyâ You Should Watch Out For
Consuming too much gluten can prompt various complications, such as a gluten allergy, wherein the immune system produces âweaponsâ to combat gluten in your system. However, a gluten allergy is not to be confused with gluten intolerance, gluten sensitivity16 or celiac disease.17 It is quite similar to other food allergies, since these are all responses to a particular allergen. Some of the most common gluten allergy symptoms are:
Coughing
Nasal congestion
Sneezing
Tightness of throat
Asthma
Tingling
Itching
Tongue and/or throat swelling
A metallic taste in your mouth
Abdominal pain
Muscle spasms
Vomiting
Diarrhea
As the book âGluten-Free Cooking for Dummiesâ further highlights, a gluten allergy may lead to adverse effects such as anaphylaxis or an anaphylactic shock that may affect different organs. People may experience agitation, hives, breathing problems, reduced blood pressure levels, fainting or even death, if the reaction is very severe.18
Warning Signs of Gluten Intolerance
Should the immune system have an unusual response to gluten in your system, then it might be a sign that you have gluten intolerance.19 Sometimes it can be mistaken for celiac disease (another gluten-related disorder) or a wheat allergy.20 The root cause of a gluten intolerance is not fully understood, although it has been linked to the digestive system, compared to celiac disease where a genetic link has been found.21
Typical gluten intolerance symptoms include bloating, belly pain, diarrhea, tiredness and a general feeling of being unwell. Someone with a gluten intolerance might also experience these indicators, although these are less frequent and already affect areas beyond the gut:
Joint or muscle pain
Anxiety
Headache
Nausea
Confusion
Numbness
If you or someone you know experiences any of these symptoms, seek medical attention immediately. This will help you determine whether you have gluten intolerance or if the symptoms occur because of other health reasons. This greatly applies if you or someone you know has severe belly pain. An extreme stomachache is not a sign of gluten intolerance, so it might be due to another potentially devastating disease that may require immediate treatment.
Having gut-related symptoms checked immediately may be helpful too, as numerous conditions that target the gut can overlap with other diseases. Fortunately, these can be examined during a checkup and your doctor may rule out other causes. Take note that symptoms of gluten intolerance are generally similar to those of celiac disease, although the reactions that people with these conditions experience arenât identical.
To diagnose a gluten intolerance, itâs important that you continue eating your usual meals, especially if itâs abundant in foods with gluten. This could help the doctor determine the main cause of the symptoms. An inaccurate diagnosis might occur if the patient decides to stop eating gluten-loaded foods prior to, or during, a consultation.22
Common Indicators of Gluten Sensitivity
In various studies, gluten sensitivity is also called non-celiac gluten sensitivity (NCGS) as celiac disease patients are sensitive to gluten too. The difference between a gluten sensitivity and celiac disease is that the former may be triggered not just by wheat, but by other grains like rye and barley, too, as these grains are known to have the glutenin and gliadin proteins (or protein fragments) also found in wheat.23
Typical symptoms of gluten sensitivity include nausea, skin irritation, bloating and gas, brain fog and fatigue. However, these indicators can widely vary and may also occur alongside gynecologic conditions, lactose intolerance and irritable bowel syndrome.24
Because there is no specific laboratory test for gluten sensitivity, your physician will have to rule out other possible causes. In some cases, patients may need to be checked for wheat allergy or celiac disease. Should test results be negative, a gluten-free diet may be advised.25 However, if any of the aforementioned tests deliver positive results, then you may want to continue eating gluten-rich foods for a more accurate diagnosis.26
Why a Gluten-Free Diet Works
A gluten-free diet is an important course of action for combating gluten-related disorders, and picking gluten-free foods is the first step in doing so. Because there are foods that are incorrectly labeled âgluten-free,â it may be quite tricky at first to select the correct items. A set of guidelines on proper gluten-free labeling standards released in 2013 by the Food and Drug Administration (FDA) may help. The organization states that for a food product to bear the gluten-free label and be considered such, it must be:
⢠Naturally gluten-free: Rice, non-GMO corn, quinoa, sorghum, flax and amaranth seed are naturally gluten-free grains.
⢠Refined to remove gluten: Gluten must be removed from any gluten-containing grain. As such, the final product should not contain more than 20 parts per million (ppm) of gluten.
Extreme vigilance is only likely if you have celiac disease, since exposure to gluten can cause sickness and threaten your health in the long run. Whatâs great about a gluten-free diet is that nearly everyone can benefit from it, whether you have a gluten intolerance or not. Grains, even whole sprouted varieties, tend to cause many problems because of the following factors:
Wheat hybridization
Gluten
Other wheat proteins
Fructans
Milling or baking process
Glyphosate contamination
Grains have high net carbs, so removing them from your diet can help improve mitochondrial function. Taking care of your mitochondrial health is important if you want to reduce your risk for problems linked to insulin resistance, such as being overweight and having high blood pressure levels, as well as diseases like Type 2 diabetes, heart disease and cancer.
Prior to beginning a gluten-free diet, consult a dietitian or health expert who can give advice on how to effectively avoid foods with gluten while eating a healthy and balanced diet.27
Best Foods to Eat if Following a Gluten-Free Diet
Once youâre given the go-signal to try a gluten-free diet, stock up on these natural and unprocessed foods:28,29
Beans (provided that you try to sprout and/or ferment your beans to reduce its lectin content, which may negatively impact your health in the long run)
Seeds (chia, pumpkin or sunflower)
Nuts (pecans, macadamias or walnuts)
Organic and pasture-raised eggs
Organic and grass fed meats that arenât breaded, batter-coated or marinated
Fish (wild-caught Alaskan salmon, sardines, anchovies and herring) that arenât breaded, batter-coated or marinated
Organically grown, GMO-free fruits and vegetables
Raw, grass fed milk or yogurt
Healthy fat sources (raw  grass fed butter, coconuts and coconut oil, olives and olive oil and avocados)
If you think going on a gluten-free diet limits eating choices and preparations, youâd be surprised to know that it wonât. Type âgluten-free recipesâ on a search engine and youâll see a wide variety of gluten-free recipes, ranging from savory to sweet. A good and delicious example is this Coconut Flour Almond Meal Pancakes Recipe from MindBodyGreen:30
Coconut Flour Almond Meal Pancakes Recipe
1/2 cup Dr. Mercola's coconut flour
1/3 cup almond meal
1 1/2 teaspoons baking powder
4 organic, pastured eggs
1 tablespoon Dr. Mercola's coconut oil, melted
1/3 cup raw cow's milk or coconut milk
1 teaspoon vanilla extract
A pinch of Dr. Mercola's Himalayan salt
1 to 2 tablespoons organic, raw grass fed butter, plus more for serving
Pure maple syrup to drizzle (optional)
Cooking Directions
In a large bowl, mix all the dry ingredients: the coconut flour, almond meal, baking powder and salt.
Slowly whisk in the wet ingredients: the eggs, coconut oil, milk and vanilla. Mix until the batter is smooth. (If it feels a little dry, add more milk until it reaches the consistency you're after).
Heat a large skillet over medium high heat. Add the butter and allow it to melt, then add scoops of batter (about a 1/4 cup each) for silver dollar pancakes. Cook for about a minute on each side until golden brown. Slather with butter and drizzle maple syrup as desired.
This recipe makes about 16 small pancakes.
Preparation time: 10 minutes
Cooking time: 10 minutes
Additional Reminders When Following a Gluten-Free Diet
Gluten Free & More magazine highlights these important tips for people who are following a gluten-free diet:31
⢠Read labels carefully: Knowing how to read labels properly will greatly help if youâre following a gluten-free diet. Ideally, never assume something is gluten-free even if the word âglutenâ isnât anywhere in the list.32 As mentioned earlier, some manufacturers purposely use other names to hide gluten in their products.
⢠If youâre in doubt, donât buy the product: If you cannot verify that the product is free of grains, donât buy or eat it at all. The same principle applies if you cannot find an ingredients list on the product.
⢠Remember that being wheat-free doesnât automatically make a food gluten-free: This is because spelt, rye or barley-based ingredients, all of which contain gluten, may be used in products with a wheat-free label on them.
⢠Introduce new foods slowly: Ensure that you incorporate only one new food at a time, and take note of symptoms before adding another item.
⢠Be a âfood detectiveâ: Call, email or write a letter to a food manufacturer to verify a productâs ingredients. Take note of the ingredient and the lot number of the food. Once you are in touch with a representative, clearly state your concerns and be persistent, polite and patient.
from HealthyLife via Jake Glover on Inoreader https://articles.mercola.com/sites/articles/archive/2018/05/19/what-is-gluten.aspx
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What Happens to Your Body When You Eat Gluten? Dr. Mercola The word âglutenâ has become such a buzzword in recent years, most likely because of the sudden popularity of the gluten-free diet thatâs been endorsed by famous personalities. Before you consider trying this diet, read this page first to learn about gluten, and how it can negatively impact your body and health in the long run. What Is Gluten? A type of protein, gluten is composed of glutenin and gliadin molecules that form an elastic bond when mixed with water. Gluten is highly noted for its adhesive abilities that can maintain a compact structure for holding bread and cakes together, and providing a spongier texture. This ability isnât surprising, considering that the word âglutenâ is derived from the Latin word for âglue.â While it does wonders for these foods, the same cannot be said for your body. Research has shown that gluten can be quite harmful for you because of the vast range of complications it might cause (more on this to come in a while). What Does Gluten Do to Your Body? A major caveat linked to gluten is its tendency to impede proper nutrient breakdown and absorption from foods, regardless if they have gluten or not. This may prevent proper digestion because excess gluten leads to the formation of a glued-together constipating lump in the gut. Afterward, the undigested gluten prompts the immune system to attack the villi, or the fingerlike projections lining your small intestine.1 This may lead to side effects such as diarrhea or constipation, nausea and abdominal pain. Excessive gluten consumption and further small intestine damage and inflammation may predispose a person to nutrient malabsorption, nutrient deficiencies, anemia, osteoporosis, other neurological or psychological diseases, and complications linked to the skin, liver, joints, nervous system and more. What Are the Types of Food That Contain Gluten? Gluten is predominantly found in whole grains like rye, barley, triticale and oats; in wheat varieties like spelt, kamut, farro, durum; and in other products like bulgar and semolina.2 Wheat-based flours and byproducts that also contain high quantities of this protein include:3,4,5,6 Wheat-Based Flours Wheat Byproducts ⢠White flour ⢠Whole wheat flour ⢠Graham flour ⢠Triticale ⢠Wheat germ ⢠Wheat bran ⢠Pasta ⢠Couscous ⢠Bread, bread crumbs and croutons ⢠Flour tortillas ⢠Cookies, cakes, muffins and pastries ⢠Cereal ⢠Crackers ⢠Beer ⢠Gravy, dressings and sauces ⢠Conventional oats (these have a high chance of being contaminated during the growing, harvesting or processing stages If thereâs another compelling reason why you shouldnât eat processed foods, itâs because these items often contain gluten. Here are examples of foods with gluten, even though theyâre not made from grains:7,8 Processed broth and bouillon cubes9 Fried foods Candies Lunch meats and hot dogs Cold cuts Dumplings Self-basting poultry Crab cakes Imitation fish Seasoned rice10 Matzo Modified food starch11 Salad dressings Seasoned chips and other seasoned snack foods Processed yogurt12 Ice cream cones Even worse, manufacturers deceive customers by âhidingâ gluten products like wheat under other names in food labels, such as:13,14 ⢠Malts ⢠Starches and other derivatives ⢠Hydrolyzed vegetable protein (HVP) ⢠Hydrolyzed wheat protein15 ⢠Textured vegetable protein (TVP) Common Signs of a âGluten Allergyâ You Should Watch Out For Consuming too much gluten can prompt various complications, such as a gluten allergy, wherein the immune system produces âweaponsâ to combat gluten in your system. However, a gluten allergy is not to be confused with gluten intolerance, gluten sensitivity16 or celiac disease.17 It is quite similar to other food allergies, since these are all responses to a particular allergen. Some of the most common gluten allergy symptoms are: Coughing Nasal congestion Sneezing Tightness of throat Asthma Tingling Itching Tongue and/or throat swelling A metallic taste in your mouth Abdominal pain Muscle spasms Vomiting Diarrhea As the book âGluten-Free Cooking for Dummiesâ further highlights, a gluten allergy may lead to adverse effects such as anaphylaxis or an anaphylactic shock that may affect different organs. People may experience agitation, hives, breathing problems, reduced blood pressure levels, fainting or even death, if the reaction is very severe.18 Warning Signs of Gluten Intolerance Should the immune system have an unusual response to gluten in your system, then it might be a sign that you have gluten intolerance.19 Sometimes it can be mistaken for celiac disease (another gluten-related disorder) or a wheat allergy.20 The root cause of a gluten intolerance is not fully understood, although it has been linked to the digestive system, compared to celiac disease where a genetic link has been found.21 Typical gluten intolerance symptoms include bloating, belly pain, diarrhea, tiredness and a general feeling of being unwell. Someone with a gluten intolerance might also experience these indicators, although these are less frequent and already affect areas beyond the gut: Joint or muscle pain Anxiety Headache Nausea Confusion Numbness If you or someone you know experiences any of these symptoms, seek medical attention immediately. This will help you determine whether you have gluten intolerance or if the symptoms occur because of other health reasons. This greatly applies if you or someone you know has severe belly pain. An extreme stomachache is not a sign of gluten intolerance, so it might be due to another potentially devastating disease that may require immediate treatment. Having gut-related symptoms checked immediately may be helpful too, as numerous conditions that target the gut can overlap with other diseases. Fortunately, these can be examined during a checkup and your doctor may rule out other causes. Take note that symptoms of gluten intolerance are generally similar to those of celiac disease, although the reactions that people with these conditions experience arenât identical. To diagnose a gluten intolerance, itâs important that you continue eating your usual meals, especially if itâs abundant in foods with gluten. This could help the doctor determine the main cause of the symptoms. An inaccurate diagnosis might occur if the patient decides to stop eating gluten-loaded foods prior to, or during, a consultation.22 Common Indicators of Gluten Sensitivity In various studies, gluten sensitivity is also called non-celiac gluten sensitivity (NCGS) as celiac disease patients are sensitive to gluten too. The difference between a gluten sensitivity and celiac disease is that the former may be triggered not just by wheat, but by other grains like rye and barley, too, as these grains are known to have the glutenin and gliadin proteins (or protein fragments) also found in wheat.23 Typical symptoms of gluten sensitivity include nausea, skin irritation, bloating and gas, brain fog and fatigue. However, these indicators can widely vary and may also occur alongside gynecologic conditions, lactose intolerance and irritable bowel syndrome.24 Because there is no specific laboratory test for gluten sensitivity, your physician will have to rule out other possible causes. In some cases, patients may need to be checked for wheat allergy or celiac disease. Should test results be negative, a gluten-free diet may be advised.25 However, if any of the aforementioned tests deliver positive results, then you may want to continue eating gluten-rich foods for a more accurate diagnosis.26 Why a Gluten-Free Diet Works A gluten-free diet is an important course of action for combating gluten-related disorders, and picking gluten-free foods is the first step in doing so. Because there are foods that are incorrectly labeled âgluten-free,â it may be quite tricky at first to select the correct items. A set of guidelines on proper gluten-free labeling standards released in 2013 by the Food and Drug Administration (FDA) may help. The organization states that for a food product to bear the gluten-free label and be considered such, it must be: ⢠Naturally gluten-free: Rice, non-GMO corn, quinoa, sorghum, flax and amaranth seed are naturally gluten-free grains. ⢠Refined to remove gluten: Gluten must be removed from any gluten-containing grain. As such, the final product should not contain more than 20 parts per million (ppm) of gluten. Extreme vigilance is only likely if you have celiac disease, since exposure to gluten can cause sickness and threaten your health in the long run. Whatâs great about a gluten-free diet is that nearly everyone can benefit from it, whether you have a gluten intolerance or not. Grains, even whole sprouted varieties, tend to cause many problems because of the following factors: Wheat hybridization Gluten Other wheat proteins Fructans Milling or baking process Glyphosate contamination Grains have high net carbs, so removing them from your diet can help improve mitochondrial function. Taking care of your mitochondrial health is important if you want to reduce your risk for problems linked to insulin resistance, such as being overweight and having high blood pressure levels, as well as diseases like Type 2 diabetes, heart disease and cancer. Prior to beginning a gluten-free diet, consult a dietitian or health expert who can give advice on how to effectively avoid foods with gluten while eating a healthy and balanced diet.27 Best Foods to Eat if Following a Gluten-Free Diet Once youâre given the go-signal to try a gluten-free diet, stock up on these natural and unprocessed foods:28,29 Beans (provided that you try to sprout and/or ferment your beans to reduce its lectin content, which may negatively impact your health in the long run) Seeds (chia, pumpkin or sunflower) Nuts (pecans, macadamias or walnuts) Organic and pasture-raised eggs Organic and grass fed meats that arenât breaded, batter-coated or marinated Fish (wild-caught Alaskan salmon, sardines, anchovies and herring) that arenât breaded, batter-coated or marinated Organically grown, GMO-free fruits and vegetables Raw, grass fed milk or yogurt Healthy fat sources (raw grass fed butter, coconuts and coconut oil, olives and olive oil and avocados) If you think going on a gluten-free diet limits eating choices and preparations, youâd be surprised to know that it wonât. Type âgluten-free recipesâ on a search engine and youâll see a wide variety of gluten-free recipes, ranging from savory to sweet. A good and delicious example is this Coconut Flour Almond Meal Pancakes Recipe from MindBodyGreen:30 Coconut Flour Almond Meal Pancakes Recipe 1/2 cup Dr. Mercola's coconut flour 1/3 cup almond meal 1 1/2 teaspoons baking powder 4 organic, pastured eggs 1 tablespoon Dr. Mercola's coconut oil, melted 1/3 cup raw cow's milk or coconut milk 1 teaspoon vanilla extract A pinch of Dr. Mercola's Himalayan salt 1 to 2 tablespoons organic, raw grass fed butter, plus more for serving Pure maple syrup to drizzle (optional) Cooking Directions In a large bowl, mix all the dry ingredients: the coconut flour, almond meal, baking powder and salt. Slowly whisk in the wet ingredients: the eggs, coconut oil, milk and vanilla. Mix until the batter is smooth. (If it feels a little dry, add more milk until it reaches the consistency you're after). Heat a large skillet over medium high heat. Add the butter and allow it to melt, then add scoops of batter (about a 1/4 cup each) for silver dollar pancakes. Cook for about a minute on each side until golden brown. Slather with butter and drizzle maple syrup as desired. This recipe makes about 16 small pancakes. Preparation time: 10 minutes Cooking time: 10 minutes Additional Reminders When Following a Gluten-Free Diet Gluten Free & More magazine highlights these important tips for people who are following a gluten-free diet:31 ⢠Read labels carefully: Knowing how to read labels properly will greatly help if youâre following a gluten-free diet. Ideally, never assume something is gluten-free even if the word âglutenâ isnât anywhere in the list.32 As mentioned earlier, some manufacturers purposely use other names to hide gluten in their products. ⢠If youâre in doubt, donât buy the product: If you cannot verify that the product is free of grains, donât buy or eat it at all. The same principle applies if you cannot find an ingredients list on the product. ⢠Remember that being wheat-free doesnât automatically make a food gluten-free: This is because spelt, rye or barley-based ingredients, all of which contain gluten, may be used in products with a wheat-free label on them. ⢠Introduce new foods slowly: Ensure that you incorporate only one new food at a time, and take note of symptoms before adding another item. ⢠Be a âfood detectiveâ: Call, email or write a letter to a food manufacturer to verify a productâs ingredients. Take note of the ingredient and the lot number of the food. Once you are in touch with a representative, clearly state your concerns and be persistent, polite and patient.
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Advocacy in Action
Sometimes just creating a different kind of energy for an uplifting moment helps us/me past a chronic experience. Even if it isnât ever seen or used on a platform.it served its higher purpose from within me. The energy aka spoons it took for me to focus and then create this title pageâŚ.seems pointless right? Not if it serves its higher path. Thank you
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#1ForAll-All4One#Chronically warriors FactFriday#curegp#CureMito#CurePOTS#Cures#Cures4All#POTS#advocacy#chronic intestinal pseudo-obstruction syndrome#colonic inertia#dysautonomia#gastroparesis#migraines#mitochondrial malabsorption
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Bananas and Avocados Can Prevent Heart Attacks Dr. Mercola By Dr. Mercola If you're fairly familiar with the vitamins and minerals in the most common fruits and vegetables, you may be aware that in bananas and avocados, potassium and magnesium are notable ingredients in both of them. Like all foods, these two powerhouse fruits (because both are fruits rather than avocados being a vegetable) have many other things to offer, but scientists have recently announced that both foods have the potential to prevent heart attacks. The research was conducted at the University of Alabama and was published in the journal JCI Insight.1 In fact, scientists have revealed that if you eat a banana and an avocado every day, you could eat yourself right into protection from heart disease, or more specifically, the atherosclerosis or hardening of the arteries that often leads to a series of disorders, NDTV2 reported. Additionally, it may also lower your risk of arterial blockages, which often necessitate surgery. It's the potassium in these foods that can alleviate a large part of the burden, the study indicates. The animal study found it reduces vascular calcification, one of the complications of kidney disease and cardiovascular disease. Mice were fed alternate diets containing low, normal or high levels of potassium, and those with the highest levels had substantially more pliable arteries, while those given lower amounts had much harder arteries. It works the same way in humans. When you include foods in your diet that contain good amounts of these minerals, these symptoms are alleviated, particularly the stiffness in arteries seen as a precursor to cardiovascular problems. Problems occur because the stiffness in arteries can cause your heart to work harder to pump blood through your body. Artery calcification is just one of the problems that having a consistent amount of adequate potassium in your diet can help prevent, and all of them are serious and related conditions: Heart disease Stroke Metabolic syndrome Chronic kidney disease (CKD) Hypertension Calcification and What It Means for Your Arteries Calcification is a buildup of calcium in your tissues, organs or blood vessels. As it's in the process of forming, it can call a halt to the necessary process that keeps your body working as it should. According to Difference Between: "Arteriosclerosis is a defect occurring in the artery (blood vessels carrying oxygenated blood) walls. It refers to hardening of the normally flexible walls due to loss of elasticity of the arterial musculature. When young, the arteries are flexible due to the presence of a protein called elastin. As age advances, there is loss of this elastin causing thickening of the arterial walls. Atherosclerosis is another condition that refers to the deposition of fat plaques and cholesterol globules within the arteries causing narrowing of the lumen of the arteries."3 The scientists noted that vascular smooth muscle cells, or VSMCs, contribute to vascular calcification in atherosclerosis and that "Arterial stiffness has become an independent predictor of cardiovascular morbidity and mortality, representing an important health problem for the nation as a whole."4 According to their research, vascular calcification may be more culpable in aortic stiffening than scientists originally thought. In fact, a 2009 study is even titled "Vascular calcification: the killer of patients with chronic kidney disease."5 The study noted: "Previously considered a passive, unregulated, and degenerative process occurring in the arterial media, vascular calcification has now been demonstrated to be a highly regulated process of osteochondrogenic differentiation of vascular cells."6 Further, VSMCs were found to produce "extracellular matrix proteins" that actually caused the arterial calcification process to happen faster. People With Less Potassium Have Higher Risks It's no secret to the scientists that potassium plays a crucial role in staving off arterial calcification and related diseases. In fact, previous studies have made it clear that the association between low blood potassium levels and death from either chronic kidney disease7 or metabolic syndrome,8 while clear, hasn't been investigated thoroughly. The study made something else clear: that "appropriate dietary potassium intake improves those pathological conditions."9 The researchers also noted that, whereas the direct influence of dietary potassium on the development of vascular calcification in atherosclerosis hadn't yet been "established and characterized," for the first time they'd been able to produce evidence that potassium was the key. While consuming too much of it can cause problems, too, such as a stomachache, nausea and/or diarrhea, according to International Business (IB) Times,10 it's clear that what you eat directly influences your risk of these serious diseases. That's why, for these diseases, especially, bananas and avocados are two of the foods containing the potassium that can lower your risk. In response to the study's findings, Dr. Mike Knapton from the British Heart Foundation observed that "With more research, we might be able to see if the disease forms in humans in a similar way and develop treatments."11 Magnesium and Potassium: Interrelationships in Regard to Health When it comes to maintaining a healthy heart, as well as properly functioning kidneys, nerves and muscles and blood pressure regulation, having an adequate intake of magnesium on a regular basis is key. Because it's the fourth most abundant mineral in your body, on which more than 600 functions hinge, getting the right amount to avoid a deficiency is critical.12 But there's more to it than that. The National Academy of Sciences assessed the role of several nutrients, including magnesium, and observed: "Magnesium has been called 'nature's physiological calcium channel blocker.' During magnesium depletion, intracellular calcium rises. Since calcium plays an important role in skeletal and smooth muscle contraction, a state of magnesium depletion may result in muscle cramps, hypertension, and coronary and cerebral vasospasms. Magnesium depletion is found in a number of diseases of cardiovascular and neuromuscular function, in malabsorption syndromes, in diabetes mellitus, in renal wasting syndromes, and in alcoholism."13 "Classic" symptoms of low magnesium include muscle spasms, unexplained fatigue, irregular heart rhythms, eye twitches and even anxiety, but those that can be difficult to spot until after it's established that low magnesium levels are what's causing the problems. Studies show that problems such as asthma and osteoporosis may also be involved, along with symptoms that indicate possible related deficiencies, including potassium. In response, experts recommend that individuals with these symptoms assume that low levels are likely the problem and begin remedying it immediately by concentrating on higher magnesium intake, either through supplementation or food, and maybe both. One of many reasons is that the body begins stripping magnesium and calcium from your bones during what is called "functioning" low magnesium. Ancient Minerals explains: "This effect can cause a doubly difficult scenario: seemingly adequate magnesium levels that mask a true deficiency coupled by ongoing damage to bone structures. Thus experts advise the suspicion of magnesium deficiency whenever risk factors for related conditions are present, rather than relying upon tests or overt symptoms alone."14 One study shows that intracellular concentrations of magnesium and potassium are closely correlated, and the ratios in your cells are what's important, not the concentrations, and hypokalemia, aka low potassium, "can be induced by the same mechanisms and are often clinically related to one another,"15 especially as they relate to cardiac arrhythmias and, arguably, other heart-related disorders and diseases. The upside is that when you begin ingesting adequate potassium and magnesium â bananas and avocados would be a great start â the above symptoms can be reversed, i.e., regulation of blood sugar, better sleep, less stress, improved mitochondrial function and increased energy. Bananas: An Example of the Adage 'You Are What You Eat' Bananas are a very popular tropical food, known for being an easy-to-carry snack that doesn't require refrigeration and can remain clean while you eat it thanks to its convenient peel. Besides high amounts of potassium, one fairly small banana (about 101 grams) provides a good amount of fiber, Nutrition Data16 reports. Vitamin B6 and vitamin C are also plentiful, as are proteins, copper and manganese. You'll want to watch your sugar intake, however, as bananas are an example of a fruit with high amounts of natural fructose; one 7-inch-long banana has 12.4 grams. However, just as the potassium content is good for you, IB Times lists a number of advantages to adding a small banana as a snack choice (or dozens of dishes that incorporate them): Bananas help balance your blood sugar level because they don't raise your glycemic index. Unripe bananas have proven beneficial for people with insulin sensitivity as they contain 15 to 30 grams of digestive-resistant starch. Eating bananas can help maintain a healthy blood pressure level. High-potassium foods can help lower your risk of developing kidney stones.17 Bananas are a wonderful addition to smoothies, making them creamy and delivering a tropical vibe, but they're also great sliced with organic raw nut butter, aside from just enjoying one for a healthy snack. Avocados: Impressive Nutritional Profile A single avocado provides very impressive nutrients that positively impact nearly every part of your body, but especially your heart and arteries. Fiber is a big one, as well as vitamin C, vitamin K and folate. To start the litany of how well avocados reach your dietary reference intakes (DRI), or how much you need to provide you with the optimal amounts, Nutrition Data18 provides data on the major nutrients one avocado contains and the percentage of daily values: Fiber â 54 percent Folate â 41 percent Vitamin C â 33 percent Vitamin B6 â26 percent Vitamin K â 53 percent Pantothenic acid â 28 percent Magnesium â 15 percent Potassium â 28 percent Avocado slices are excellent on sandwiches and salads, topped with mozzarella, basil and black pepper, mixed with salsa and chopped papaya or with poached eggs. Other foods containing magnesium include greens such as spinach, romaine lettuce and Swiss chard, crucifers like broccoli, cauliflower and Brussels sprouts, seeds and nuts, fatty fish, such as mackerel and wild-caught Alaskan salmon, specific spices such as fennel, basil, cloves, chives and cilantro, fruits including papaya, watermelon, raspberries and strawberries, and grass fed yogurt. Good potassium sources include beet greens, carrots, cantaloupe, oranges and most of the foods listed above. If you've experienced any of the symptoms listed, upping your intake of these foods can likely improve them and may serve to relieve other problems as well.
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A Minuet
A Minuet Within our grasp we hold a tiny bit of breath In each of our lives there are choices we take and choices we make We dance a slow minuet of grace of these breathes we take. A demitasse of a sip we inhale our moment in strength. A ballet began before we were born then we began our minuet. The dance of breathes toward our strength. Is your two step serving, you, us, all? In this,âŚ
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#CIP#POTS#advocacy#Chronic Journey#colonic inertia#comfort#gastroparesis#incurable#migraines#mitochondrial malabsorption#motility digestive tract issues#optimism#positivity#strength
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Hair Restoration Non Surgical Procedure | Reno NV
Anti Aging Professional is an All natural Medical professional In Reno NV Offering Resolutions to Hair Loss with Practical Medication.
Even a Holistic Medical professional in Reno NV has actually to be concerned about thinning hair. However that does not admire a great head of hair? We wish for, covet, or even prayer a terrific head of hair? Millions are not so fortunate. Go on go look in the mirror and also examine it out. Always remember the spot on the back of your head. Yes, women you as well.
Right here are some techniques to a service that will certainly assist your thinning hair. Reno Holistic Physician William Clearfield has an alternate health method as well as started the Hair Restoration Project here in Reno as well as recently appeared on the "Ask The Medical professional" segment on KTVN Channel 2 News right here in Reno NV discussing options for loss of hair. It is very insightful as well as entertaining. View by clicking link below.
http://www.ktvn.com/story/36080088/ask-the-doctor-hair-loss
Go here to figure out even more details on the Hair Remediation Project
http://drclearfield.net/hair-restoration-project/
This article will certainly give you a "head" begin ... Yes, all right no a lot more negative word play heres.
Below are suggestions that will help you and could stun you, especially the very first one. If you have any kind of inquiries please do not hesitate to schedule an appointment to go over treatment remedies.
1. Appropriate Hypothyroidism Medical diagnosis & Therapy (13-14).
Yes, think it or not, your thyroid can affect your hair follicles. The thyroid operates as the body's "gas pedal." Like Goldilocks, we require it to be perfect, not as well little, not excessive.
98% of all thyroid disorders cause hypothyroidism. Common signs include being cool constantly, weight gain that can't be explained, being tired all the time, thinning of the hair, the outer third of the eyebrow, the skin as well as the nails, boosted body fat, energy loss, memory loss, moody, low body temperature (never ever more than 97.6 F), preserving water, as well as just not really feeling fairly appropriate.
2. Nutritional deficiencies.
Nutritional shortages, specifically silica and zinc results in hair loss.
Trick Supplements for Healthy and balanced Hair (15).
Biotin- Water-soluble B-vitamin discovered in green leafy veggies. Controls mitochondrial enzymes in hair follicles. Depleted by smoking, aging, excess alcohol, laborious exercise, melt victims, shortened intestine disorder (GI resections), achlorhydria, and also raw egg intake. (16-17) Usage orally or in essential oil blend. Dosage is 30-100 mcg/day.
Zinc -Advertises cell recreation, cells growth and also fixing of damaged cells. Preserves the oil-secreting glands affixed to hair follicles. Research study revealed that 15 clients with alopecia areata obtained 45 mg of zinc TID. All had complete return of hair growth within 6 months. (18) Upkeep dose is 15 mg each day in addition to 1 mg copper as a balance.
Maintenance dosage is 15 mg per day along with 1 mg copper as a balance.
N-Acetyl-Cysteine- Precursor to glutathione one of the most effective antioxidant in the body. Safeguards DNA from chemical damages, detoxes heavy metals, and also it maintains arteries as well as airways open. It turns on vital features of the immune system.
B Vitamins (B6, B12)- Through Pyridoxal 5-Phosphate (PLP), the B Vitamins act as drivers to trigger the enzymes as well as chain reactions to begin the metabolism of keratin and melanin in the hair roots. B vitamins control hormone release., managing androgen communication with hair metabolic process. Testosterone breaks down into dihydrotestosterone (DHT). Elevated DHT levels diminishes hair growth by decreasing the size of the anagen, hair growth stage, and the hair follicle dimension. Vitamin B6 binds to the testosterone receptors, quiting DHT formation.
Niacin- Vitamin B3 transforms carbs into energy, supplies the power to cells where required as well as preserves cell honesty. Niacin is a vasodilator, for this reason the niacin "flush" so typical when taken, "washes" carbohydrates through the body, decreasing natural fat as well as lotion cholesterol. The flush can be lessened by taking niacin with a dish or starting (with a) reduced dosage as well as slowly raising its strength.
The vasodilator impact of niacin provides raised oxygen as well as nutrients to the hair follicle resulting in thicker.
hair.
Arginine- L-arginine, a forerunner to nitrogen oxide, opens the potassium channels of the cell, boosting blood supply to the hair origin.
Lysine- A necessary amino acid, lysine boosts collagen as well as is necessary for recovering harmed hair.
Food sources for lysine consist of fish (especially salmon, sardines and cod), milk, fowl, red meat, pork, vegetables, nuts, spirulina and pulses.
Saw Palmetto (for Guy)- Prevents conversion of testosterone to DHT Acetyl-L-Carnitine- Up manages proliferation and also down regulates apoptosis in hair roots keratinocytes. Transforms fat into energy. Acetyl-L Carnitine boosts the membrane possibility of the hair follicle which is considerably lessened in addition to potassium channel feature within withering hair follicles.
Iron- A lack of iron leads to a decrease in hemoglobin, the active ingredient that brings oxygen for growth.
and also repair of all cells including hair follicles. Iron deficiency states relocate hair roots into a.
early as well as extended telogen (relaxing) phase.
Hair growth is a "non-essential" physical feature. It is among the very first systems to close down in a state.
of iron deficiency. Therefore, hair loss is an early indication of iron shortage anemia.
Vitamin D- Essential for calcium homeostasis, immune regulation, and also cell development. A host of autoimmune diseases, including alopecia areata, show reduced degrees of Vitamin D. The extent of product 25( OH) D deficiency is inversely associated to the extent of hair loss.
Gluten- Hair loss is an early indicator of gluten intolerance. In all cases of alopecia or substantial hair loss, we recommend a rigorous gluten totally free diet plan for 4 weeks as a trial. (19).
Vitamin A- Loss of hair is a symptom of Vitamin A toxicity especially in renal failing. Typically, resolves when toxicity is addressed. (20).
Emu Oil- Has linolenic acid a powerful 5-alpha reductase prevention. Substance with virgin coconut.
oil to create an antibacterial, anti-inflammatory scalp treatment to DHT.
3. Sufficient Protein.
Insufficient healthy protein impacts on your hair growth. The CDC advises 46 to 56.
The CDC recommends 46 to 56 grams of protein per tain to keep hair development. (21).
Poor healthy protein leads to healthy protein rationing by closing down lesser features.
4. Iron.
When iron levels drop listed below 30 mg/L hair development and also regrowth are lowered. Iron deficiency frequently triggers hair to be fragile and also dry with narrowing or splitting of the hair shaft. Iron replacement restored hair growth in those whose sole issue was iron deficiency. (22-23).
5. GI Evaluation-The 4 R's.
Diminished belly acid brings about impaired healthy protein food digestion and reduced nutrient absorption. Interrupted GI flora results in inadequate nutrient application. Pancreatic enzyme deficiency brings about malabsorption of crucial fats and also zinc.
The "4 R's" include (24):.
" Eliminate" inflammatory foods such as gluten, dairy, corn, soy, eggs as well as sugar. Get rid of gastric toxic irritants like alcohol, caffeine or drugs. Infections, also reduced quality infections have to be treated with herbs, antiparasitic and antifungal medication, anti-fungal supplements and antibiotics when appropriate.
" Change" crucial nutrients for proper utilization of foods items. Digestive enzymes, hydrochloric acid as well as bile salts are required for proper digestion. "Recover" normal GI plants. Probiotics having bifidobacteria and also lactobacillus.
" Restore" normal GI plants. Probiotics including bifidobacteria as well as lactobacillus dosed from 25 to 100 billion systems a day along with prebiotics and fiber.
" Repair service," L-glutamine in addition to zinc, omega 3 fish oil, vitamins A, C, E, unsafe elm as well as aloe vera having supplements reconstructs the broken intestinal wall.
I wish you found this short article "Holistic Physician Reno NV 5 Solutions to Loss of hair" practical in your begin to an all natural functional different medication health and wellness option in Reno, Carson City as well as Sparks NV.
Contact Dr. William Clearfield's office to aid with your services and customized therapy strategy.
Make sure to enjoy our weekly Reno acupuncture pointers at https://goo.gl/HcK7Gt.
Visit our Google+ page at https://goo.gl/wVHapb.
Facebook at www.facebook.com/DrwilliamClearfield/.
Visit our website at drclearfield.net/medical-acupuncture/.
William Clearfield DO.
Address: 9550 S. McCarran Blvd., Collection B.
Reno, NV 89523.
Phone: 775-359-1222.
Fax: 888-977-3503.
Email: [email protected].
Internet site: drclearfield.ne
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Protocol for aging and degeneration
Popular six step program rebuilds your body and organs
BC's top anti-aging pros teach us that people seldom die of old age; they die of preventable complications of the accumulating damage.Â
Aging has been described by science as your body's reduced ability to repair any damage that does occur over the day, during its regeneration period at night. The major preventable causes of "age-related death" are congestive heart failure, heart attack, and kidney (renal) failure and cancer. All have been found to be oxidative disorders, most of the senior diseases are preventable, and that is a main reason for this blog. So let's just hit six basic concepts to live longer and with more vitality.
Kick your metabolism back into youthful repair
If you could say "one end" of an anti-aging program simply stops the damage with antioxidants, the "other end" simply increases the speed of healing and repair. If you work both ends back towards the middle, the outcome is vastly improved rehabilitation and obvious metabolic increase, accompanied by improved scientific "youth markers" across the board, wherever you can take the readings. To the layperson it's OK to call the approach "anti-aging", although we all know you must age at least a little. The rate of repair is governed by a human growth hormone (HGH) inducer, which forms other growth factors and improves your own glandular levels and outputs, usually in balance. The levels are enough to produce reliable effect, yet there is a natural feedback loop so you can only approach perhaps the HGH release of your early twenties with it, which is about half of what you developed at 12-14 years of age. It works well and the top anti-aging specialists don't even do a baseline or hormonal assay when they put you on an anti-aging program because the readings move so much as you become more youthful that early readings will be meaningless. Dr's White and MacLeod in Kelowna have patients on their own formula for 6 months before doing hormonal baseline, if they do one at all. The amino acids formula I mostly used over the years was their SomaLife gHP but more recently I've gone back to the original Isidori study that I show in the Medicine Bag today. You can blend your own and follow Isidori with arginine pyroglutamate and l-lysine at a reasonable cost from PureBulk. Don't forget, when you're regenerating mass and internal organs you need more good food and supplements. Some people like the more direct approach of using the IGF-1 growth factor in bovine colostrum. We have that too in the shortlist and found good results with it as well. At any rate HGH references show that growth hormone or IGF-1 therapy increases heart and kidney size and function, and HDL (good) cholesterol, and improves bone mineralisation and osteoporosis. HGH therapy improves metabolic syndrome, reduces triglycerides, and even repairs the damaged myelin found in neurodegenerative disorders such as Alzheimer's ALS, and Multiple Sclerosis. Science has shown that the common denominator in aging, fibromyalgia, diabetes, and obesity, is growth hormone (HGH) deficiency and the inability to repair effectively. HGH therapy is the foremost treatment for fibromyalgia; it also improves immune system function and in fact rebuilds all the organs such as the bowel lining, skin, kidneys, eyes and heart already mentioned, with the heart repair and improvement seen with the therapy even after a heart attack.
Growth hormone production falls off markedly with age, and in seniors increasing it to youthful values for several months can make one look and feel 10-15 years younger. The immune system is impaired with age as the thymus gland shrinks, less recovery takes place and fewer white blood cells might be produced due to reduced growth hormone repairing the gland. But immune response also drops with stress from any source, such as nutritional deficiency, chronic infection, emotional stress, illness, electromagnetic pollution, free radicals/oxidative stress, drugs, and leaky gut syndrome.
Reduce the damage that does occur, eliminate "Age-Related Cofactors for Disease"
Don't underestimate the importance of your body's most powerful healing agent. The antioxidant glutathione drops with age and is also depleted with free radical and toxin load, AKA oxidative stress, illness, inflammation, infection, and other insults. Dr's Rath and Pauling's company promotes a heart disease cure that is very high in antioxidants such as vitamin C, but oddly, low in glutathione precursors. The biggest user of glutathione as it's breaking down toxins is the liver. Glutathione is directly involved in mitochondrial ATP energy production and it is also the main protector of the mitochondria. It is also the main support for the immune response, which is of interest because several studies link chronic infection to accelerated degeneration. When glutathione levels are low, infection is stimulated, and when high, infection is reduced. See the Medicine Bag shortlist for the cold-processed whey.Â
Jack up metabolic rate and mitochondrial energy
Of all the issues one could come up with, mitochondrial disorders are among the most serious. When it comes right down to it, that is life and death. Mitochondrial disorders, according to medical courses, can be caused by toxin load when they are not inherited. The reason why they are often seen as age-related may be reduced to accumulation of enough toxin load and low enough oxygen delivery to cause symptoms. The causes of mitochondrial impairment may be many, but as you'll see all of these diseases are more likely just different manifestations of the same disorder. Anything that can impair mitochondrial production of ATP energy, for example unsaturated oils, can kill or delete mitochondria, suffocating the cell, and result in degenerative disease or cancer. Toxin load unbalances biological function  and sometimes, as in cancer or fibromyalgia, a trigger mechanism may catalyse the event into becoming apparent where the body had previously been maintaining equilibrium AKA 'homeostasis' despite the toxin load. Severely limiting carbohydrates and favouring fibrous vegetables, and taking an antioxidant program of at least vitamin A, C, E, D, and coenzyme Q-10, improves mitochondrial ATP production.Â
Make sure the heart can take it; improving total cirulation
A crucial anti-clotting enzyme plasmin drops with age, causing thick blood, reduced oxygen to the tissues, clots, inflammation, fibrosis in the internal organs; excessive clotting also increases in illness, free radical damage/oxidative stress, and inflammation. So we're all over it and there's plenty of reference in the Medicine Bag and shortlist  about reducing inflammation and heart risk, but essentially you can use enzymes to support falling enzyme levels as well as improve circulation for the rest of your life. It will maintain cognitive ability via better microcirculation too.
Feed the flora; bowel probiotics and prebiotics for many reasons
Feed the good bowel flora (probiotics) so they outcompete pathogenic organisms in the gut. This will reduce toxin production in the gut that goes on 24 hours a day. Eating probiotics doesn't really provide the numbers needed to effect much change. Regardless of whether there is a known bowel disturbance, bowel malabsorption is common due to gut acidity (pH) being incorrect. Inulin, a PREbiotic, supports correct bowel ecology and pH and results in better nutritient absorption. The seat of immune response is the gut, so this part of the loop is important to not being overwhelmed by infection as you age.
Improve Nutritional Profile
Cold processed whey supplies very bioavailable proteins that are much more easily absorbed than meat or eggs in addition to supplying glutathione precursors. It contains all of the essential amino acids and two of the glyconutients used in the healing process. It's suitable especially for the very young, very old and those with a compromised immune system. Macrominerals like magnesium and potassium are usually deficient, as are the b-vitamins and vitamin D, so should be supplemented in fairly generous quantities, for example a gram or more each of magnesium citrate and potassium chloride (No-Salt for example), 5,000 IU vitamin D, B-100 complex, and an extra gram or so of niacin or no-flush niacinamide, humic/fulvic minerals and magnesium chloride....and selenium is crucial for glutathione production. Do all that over a good diet.
Reduce exposure to inflammation-causing food.
Dietary changes are important for reducing oxidative stress. While unsaturated oils are readily oxidized, saturated fats and coconut oil are low oxidizers that do not contribute to oxidative stress. Well-referenced articles such as Mary Enig's The Oiling Of America and The Cholesterol Myths, which are available online, address public misconceptions on dietary fats and cholesterol. Alpha-linolenic acid (ALA), a component of Flaxseed oil, is a NON-essential omega-3 that was once thought to be a 'good' omega-3 oil. Research has revealed there is no known need at all for ALA except for a tiny amount of conversion to the real omega-3 essential fatty acids EPA/DHA. That abysmal performance has traditionally escaped the followers of Joanna Budwig and Udo Erasmus, but fatty acids expert Dr. Floyd Chilton fully explains it in his book Inflammation Nation. Chilton says (on page 97),"I wish I could tell you that the (ALA) in flaxseed oil could replace wild fish as a rich source of EPA and DHA but the scientific literature simply does not support this contention. ...We do the conversion but very slowly, and we also eat a lot of fatty acids such as LA that 'compete' for enzymes that convert ALA to EPA and DHA, further limiting its conversion." This competition for fatty acids uptake is most pronounced in the sad North American diet with its low EPA/DHA and higher omega-6 fatty acid intake due to corn, canola, soy, and safflower oil intake. The fact that cell walls contain negligible ALA and are high EPA and DHA explains why one may need vastly more EPA and DHA than an ALA supplement can provide, and also explains why fish or krill oil supplements are more popular for inflammation than flax oil. Fish liver oil and cod liver oil improve cell membrane function and integrity. Unlike ALA, fish oil's EPA and DHA are essential to health and can reverse illnesses such as coronary heart disease, skin disorders and cancer. Wild salmon oil, even minimally refined oil, has almost no impurities. Inflammation can be further reduced by adding GLA or Borage oil if your EPA/DHA are attended to. It's been pretty clear in recent medical news that carbohydrate loading is inflammatory, and long-term high loading has been linked to oxidative disorders such as Alzheimer's disease. Reducing carbohydrate loading facilitates normal metabolic function, and controlling/improving lymph and cell alkalinity should be considered, with a view of compensating for carb loading you do have, following Otto Warburg's Nobel Prize work on oxygen carrying ability of alkaline tissues and cancer.
Ditch the drugs, or at least reassess as you get younger
Generally, drugs cause a degree of cellular impairment and many even cause mitochondrial damage even on their own, aswas proven in the case of the statin drug class of cholesterol medication. These cause muscle wasting due to mitochondrial deletion, which is long-term, almost permanent that repair is so slow. Obviously, removing toxins from the diet and environment would be an advantage and depending on the drugs, maybe you don't need them.
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Actionable Advocacy our Authentic Voice
Actionable Advocacy our Authentic Voice
A chronic journey advocate who, like many of you, found this pandemic an empathetic challenge. While at the same time an opportunity to become stronger spiritually, mentally, emotionally, and chronically through introspection. It doesnât happen overnight, ever! Chronic warriors who have been on a long chronic journey can especially relate to this statement. Chronic migraines began inâŚ
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#ActionableAdvocacy Cures#CIP#Empathy#GP#MitochondrialDisease#POTS#Sjogrens#authentic voice#Chronic Journey#chronic migraines#colonic inertia#Coronavirus#diagnoses#gastroparesis#mitochondrial malabsorption#Pandemic#quality of care#quality of life#research#treatments
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Itâs Like This
Itâs like this âŚ. Chronic journey #BeYou! Everyday always 24/7/2020 Everyday is a masterpiece Every moment is fabulousitynessuniqnes Magnificent on blast + actified You are an exquisite blessing matched by no one! Every breath an attribute to be timelessly treasured whenever you have enough energy Chronic warriors are unconditionally empathetically understanding w/ #advocacy love, support,âŚ
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#1ForAll_All4One#2020Motility#Advocates#BeYou#ChronicWarriors#CIPO#curegp#CureMito#CurePOTS#Cures4Chronic#Empathy#FGIMD Gastroparesis#spoonie#advocacy#Dehydration#energy#gastroparesis#malnutrition#mitochondrial malabsorption#spoons
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A Recipe for Hope
A Recipe for Hope
A recipe for finding hope in a valley of unknown.
This is not an overnight, snap your fingers, blink of an eye, recipe. Like the many layers, most of us live with, it is gradually built/earned overtime.
Unknown in the chronic journey includes many moments of uncertainty, a lot of waiting, periods of time without answers. All the while, battling for the care you need to live your life. We whoâŚ
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#1Voice1Cure#ButYouDontLookSick#ChronicMigraine#CIP#curegp#FGIMD#green4gp#Hope#HR1187#IBS#invisibleillness#POTS#spoonie#advocacy#Chronic#ChronicRainbows#ColonicInertia#mitochondrial malabsorption#recipe
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