#margaret brimble

[whats-in-a-sentence]

In other work, the Brimble group recently accomplished more efficient synthesis of gamma-rubromycin (figure 21.8), a potent inhibitor of human telomerase.

"Chemistry" 2e - Blackman, A., Bottle, S., Schmid, S., Mocerino, M., Wille, U.

[noisynutcrusade]

Debut drug for Rett syndrome at edge of approval | Spectrum

Margaret Brimble was a new professor in 1999 at the University of Auckland in New Zealand. The country was not exactly known as a hotbed of drug development, but Brimble was an optimist, a dedicated chemist and maybe even a bit of a dreamer — she was working to create new drugs for traumatic brain injuries at a spinout company called Neuren Pharmaceuticals. She and three chemists from her lab…

[flammentanz]

Miss Marple in Germany

Joan Hickson as Miss Jane Marple and David Horovitch as Detective Inspector Slack in “4.50 From Paddington“ 

While the four movies starring Margaret Rutherford as Miss Jane Marple are hugely popular over here in Germany and they are constantly repeated on television this series is only known to Insiders and is only very rarely broadcast.

The series was first broadcast on East German television in 1986 and was dubbed magnificently. When I later heard Joan Hickson in the orginal version I was amazed how similar the voice of her German voice actress Gertraud Klawitter sounded.

Right from the beginning I had a soft spot for David Horovitch as Detective Inspector Slack whose boundless energy is always wasted on the wrong suspect. His facial expression when ever he unexpectedly meets Miss Marple is just priceless and his constant shouting at his poor assistant Lake (Ian Brimble) or at somebody else is so amusing.  

[swldx]

RNZ Pacific 1207 8 Jun 2022

7245Khz 1147 8 JUN 2022 - RNZ PACIFIC (NEW ZEALAND) in ENGLISH from RANGITAIKI. SINPO = 54444. English, music until pips and news @1200z anchored by Vicki McKay. QRM=Navy Amatuer Radio Club (NARC) Net SSB. Alan Hall spent a total of 19 years behind bars for the murder of Arthur Easton, a crime he always maintained he did not commit, before the conviction had been quashed by the Supreme Court. The NZ government is welcoming a proposal by the farming sector for how farming emissions should be paid for. Damian O'Connor says the proposal strikes the balance between reducing emissions responsible for climate change while keeping farming profitable. At least 33,000 women were overdue for their routine cervical smears. The number of women who had missed a smear had increased over the past three years, partly due to Covid-19 restrictions. The DHB did not reach its target of seeing 80 percent of women aged 25 to 69 years, in the year to March. Catching up on planned care would take a significant amount of time because the DHB was now dealing with a surge in winter illness. Ports of Auckland has announced it will scrap the automation of the Fergusson Container Terminal, leaving $65 million of automation software and guidance system useless. Auckland Council said it would seek a review of decisions made by the former chief executive and board of directors of the Ports of Auckland Ltd (POAL) to commence the project back in 2016. Three police officers in Tempe, Arizona have been placed on paid leave after refusing to help a drowning man in a reservoir. The Police Union says attempting to save him would have been dangerous. Dame Margaret Brimble, a University of Auckland scientist known for her drug discoveries, won a top international chemistry prize, the Pedler Award, for her team's discovery of the drug "trofinetide" which proved a successful treatment for the neurogenetic disorder Rett Syndrome. Sports. @1205z trailer for RNZ "Our Changing World". @1206z Weather Forecast: Severe Weather Warnings for Rain until Monday. Showers, Rain, Thunderstorms, Hail. @1207z "All Night Programme" anchored by Vicki McKay. Backyard fence antenna, Etón e1XM. 100kW, beamAz 325°, bearing 240°. Received at Plymouth, United States, 12912KM from transmitter at Rangitaiki. Local time: 0647.

[norton-addiction]

Who is in it?

Series three will also welcome back old favourites including Sidney’s housekeeper Mrs Maguire (Tessa Peake-Jones) who will be on hand to keep the vicar in check. Morven Christie has reprised her role as Sidney’s forbidden lover Amanda, while Kacey Ainsworth is back as Geordie’s long suffering wife Cathy.

Others returning include Al Weaver as Leonard Finch, Lorne MacFadyen as DC Phil Wilkinson, Seline Hizli as police secretary Margaret and black Labrador Dickens.

Will there be new faces?

Doctor Who star Peter Davison will be a new addition, playing the village solicitor Geoff Towler “who rules his family with a rod of iron”. Former EastEnders actor Gary Beadle has also joined as Archdeacon Gabriel Atubo.

What will happen?

Series three will see a duty versus love conflict with Sidney and Amanda. After leaving her husband for the vicar during the Christmas special – Sidney is now plagued by the knowledge that as a clergyman he must put duty above his own needs and lead by example. Speaking about his onscreen relationship, Norton said: “They are resisting or denying the impending decision: If Amanda divorces Guy she can’t marry Sidney and she can’t have a relationship with Sidney unless he leaves the church. So it sets up this duty versus love conflict.”

Elsewhere Mrs Maguire’s friendship with Jack (Nick Brimble) develops, Leonard looks for romance elsewhere after Daniel (Oliver Dimsdale) left him for another man and, despite being married to Cathy, Geordie feels a spark between himself and Margaret.    

When is it on?

The six-part series will kick off on Sunday, April 23 at 9pm.

[elvisomar]

Margaret Brimble

(born 1961) Chemist

Margaret Anne Brimble is a chemist best known for her investigations of shellfish toxins, as well as treatment for brain injury. She is Chair of Organic and Medicinal Chemistry at the University of Auckland and is also a Principal Investigator at the Maurice Wilkins Centre for Molecular Biodiscovery. She was named Companion of the New Zealand Order of Merit, and is a Fellow of the Royal Society of New Zealand.

Number 235 in an ongoing series celebrating remarkable women in science, technology, engineering, and mathematics.

[londontheatre]

It’s almost always a bold move to present a relatively rarely performed work. Dear Brutus imagines, as far as I could deduce, some sort of parallel universe in the form of a wood (that is, an area of woodland) that only appears on Midsummer’s Eve. The show’s characters enter, undergo varying levels of transformation, and when they return to the real world, see themselves and one another as they have never done before. It’s absurd as it sounds, and it’s one of those shows best enjoyed by simply doing one’s best to go along with proceedings. After all, isn’t theatre ‘make believe’ as it is?

J M Barrie’s script contains an unusual amount of description, with some very specific background details with regard to the characters. It’s worth a read to gain some additional insight into the play. To an extent, it’s regrettable that this is so, as a comprehensive understanding of the play should, ideally, be evident just by watching the production. Anyway, why is it, for example, that Mr Coade (James Woolley) insists on going out of his way to provide a footrest for Mrs Coade (Josie Kidd) whenever she sits down, despite having no walking impediment or leg pain? What does Lady Caroline Laney (Helen Bradbury) hope to achieve by deliberately mispronouncing her r’s as w’s?

The costumes are commensurate with the era being portrayed, as is the on-stage furniture. But I struggled with this production at times, particularly in watching and listening to someone in the wood counting to 100. The dialogue between Margaret (Venice van Someren) and Will Dearth (Miles Richardson) was too repetitive for my liking, though it produced a mildly amusing comic effect. The best humour is reserved for a love triangle given prominence in all of the show’s three acts, between John Purdie (Edward Sayer, a young talent who could well have a long and successful career judging by his compelling performance here), Mabel (Bathsheba Piepe) and Joanna (Charlotte Brimble).

They really don’t write plays like this anymore, with extensive but nonetheless accessible vocabulary and putdowns spoken with finesse. Some interesting set design decisions correlate well with the story: a decent effort to create ‘the wood’ does not result in a later clear-up when the play returns to the house of Lob (Robin Hooper). In a proverbial sense, what happened to the characters in the wood stays with them long after they have left it. Simon Rhodes as Matey, butler to Lob, has remarkable timing and stage presence.

Performed ‘in-the- rectangle’ (as opposed to ‘in-the-round’), there are moments when characters are speaking from opposite ends of the stage, such that much of the audience is watching a conversation as though the stage were a tennis court. Overall, the show was performed with great aplomb, but in the end, the idea of getting a second chance is just pure fantasy: life is never a dress rehearsal, as you know. Still, fans and followers of Barrie’s works will find much pleasure in this well-directed production.

Review by Chrs Omaweng

1917. In a remote English village there are rumours of an enchanted wood. One of the inhabitants – a mysterious old man – invites eight strangers to stay. They all have something in common. When, one evening, the wood miraculously appears the guests feel compelled to enter. What happens there has the power to change their lives forever…

From J. M. Barrie, the celebrated writer of Peter Pan, The Admirable Crichton and Quality Street, comes this haunting drama of self-revelation. Darkly comic, and presented in a sumptuous production for the play’s centenary year, Dear Brutus is Barrie at his most magical.

Directed by Jonathan O’Boyle (Sense of an Ending – Time Out Critics’ Choice) and produced by Troupe, who return to Southwark Playhouse after their critically acclaimed production of The Cardinal (The Telegraph Critics’ Choice).

Troupe presents DEAR BRUTUS by J. M. Barrie. Directed by Jonathan O’Boyle. Designed by Anna Reid. Lighting Design by Peter Harrison. Sound Design by Max Perryment. Wednesday 29 November – Saturday 30 December 2017 http://ift.tt/NsSQwM

http://ift.tt/2A5GkFM London Theatre 1