#label free detection systems market size

[shivshaktimachtech]

Ayurvedic Hair Oil Bottle Packaging Line Manufacturer

Shiv Shakti Machtech is an Ayurvedic Hair Oil Bottle Packaging Line Manufacturer in Ahmedabad. We are Based in Ahmedabad, Gujarat, India. Ayurvedic Hair Oil Bottle Packaging Line efficiently packages Ayurvedic oils using specialized machinery and processes. Our packaging line fills, seals, labels, and prepares hair oil, preserving quality and consumer appeal. Features: Precision Filling: Our automated filling systems ensure accurate dosage for each bottle, reducing waste and ensuring consistent product quality. High-Speed Capping: Boost production with our efficient capping machines, ensuring secure, tamper-evident seals to protect hair oil. Customizable Bottle Design: Choose from diverse bottle shapes, sizes, and materials, including glass and eco-friendly options, for your brand. Quality Control: Integrated inspection systems detect defects in bottles or labels, ensuring only the highest quality products reach market. Eco-Friendly Options: Opt for sustainable packaging materials and processes, reducing environmental impact while maintaining premium quality. Shiv Shakti Machtech is Ayurvedic Hair Oil Bottle Packaging Line Manufacturer in Ahmedabad, Supplier in Kathwada, Vadodara, Changodar, Gota, Naroda, Nikol, Mehsana, Palanpur, Deesa, Patan, Vapi, Surendranagar, Bhavnagar, Jamnagar, Junagadh, Rajkot, Amreli, Mahuva, Surat, Navsari, Valsad, Silvassa, Porbandar, Mumbai, Vasai, Andheri, Dadar, Maharashtra, Aurangabad, Kolhapur, Pune, Rajasthan, Jaipur, Udaipur, Kota, Bharatpur, Ankleshwar, Bharuch, Ajmer, Delhi, Noida, Baddi, Solan, Himachal Pradesh, Una, Jammu Kashmir, Haryana, Hisar, Gurgaon, Gurugram, Madhya Pradesh, Indore, Bhopal, Ratlam, Jabalpur, Satna, New Delhi, Kolkata, West Bengal, Assam, Asansol, Siliguri, Durgapur, Bhubaneswar, Odisha, Brahmapur, Puri, Goa, Amaravati, Andhra Pradesh, Visakhapatna, Hyderabad, Guntur, Chittoor, Kurnool, Vizianagaram, Srikakulam, Karimnagar, Ramagundam, Suryapet, Telangana, Medak, Bengaluru, Bangalore, Mangaluru, Hubballi, Vijayapura, Davanagere, Kalaburagi, Chitradurga, Ballari, Kolar, Chennai, Coimbatore, Madurai, Tiruchirapalli, Tiruppur, Salem, Erode, Tirunelveli, Tamil Nadu, Kerala, Kochi, Thiruvananthapuram, Kozhikode, Thrissur, Kollam, Alappuzha, Kottayam, Kannur, Malappuram, Bharatpur, Jodhpur, Bikaner, Alwar, Bhilwara, Nagpur, Amravati, Solapur, Malegaon, Navi Mumbai, Thane, Wardha, Vasai-Virar, Gondia, Hinganghat, Barshi, Ulhasnagar, Nandurbar, Bhusawal, Pimpri-Chinchwad, Kalyan, Satara, Yamuna Nagar, Chhachhrauli. For further details or inquiries, feel free to reach out to us. View Product: Click here Read the full article

[autopackmachines]

Enhancing Quality and Consistency: Benefits of Lotion Filling Machines

In the ever-evolving landscape of personal care and cosmetics, quality and consistency are paramount. For manufacturers in the lotion and skincare industries, maintaining high standards across every product batch is crucial. This is where lotion filling machines come into play. These machines have revolutionized the way lotions and creams are packaged, offering numerous benefits that enhance both the quality of the product and the efficiency of the production process. In this blog, we will explore how lotion filling machines contribute to achieving superior quality and consistency.

Precision in Every Pump

One of the most significant advantages of lotion filling machines is their precision. Modern filling machines are engineered to deliver exact amounts of product into each container. This precision minimizes waste, reduces the risk of overfilling or underfilling, and ensures that every bottle or jar contains the same amount of product. For consumers, this translates into a more consistent experience with each purchase, fostering trust and loyalty.

Consistency Across Batches

Achieving consistency across different production batches is a challenge that many manufacturers face. Variations in filling volumes, air bubbles, or inconsistent texture can affect the final product's quality. Lotion filling machines are designed to maintain uniformity, even when production scales up. Automated systems and advanced controls ensure that every batch meets the same high standards, providing a reliable product every time.

Enhanced Quality Control

Lotion filling machines often come equipped with sophisticated quality control features. These can include sensors that detect fill levels, automatic capping, and sealing mechanisms that reduce the likelihood of defects. Additionally, some machines offer real-time monitoring and data logging, allowing manufacturers to track and analyze production metrics. This level of oversight helps identify and rectify issues promptly, ensuring that only products meeting strict quality standards reach the market.

Increased Efficiency and Productivity

Efficiency is a critical factor in the production of lotions and other liquid products. Manual filling processes can be time-consuming and prone to human error. In contrast, lotion filling machines streamline the production process, increasing throughput and reducing labor costs. Automated systems can fill, cap, and label products at high speeds, allowing manufacturers to meet high demand and scale operations without compromising on quality.

Flexibility and Customization

Modern lotion filling machines offer a range of customizable features to accommodate different types of products and packaging. Whether you're filling thick creams, runny lotions, or even more specialized formulations, there is likely a machine designed to handle your specific needs. Additionally, many machines can be adjusted to accommodate various container sizes and shapes, providing manufacturers with the flexibility to innovate and adapt to changing market trends.

Improved Hygiene and Safety

Maintaining a clean and hygienic production environment is crucial in the cosmetics industry. Lotion filling machines are typically designed with easy-to-clean components and hygienic sealing to minimize contamination risks. Automated systems reduce the need for direct human contact with the product, further enhancing safety and cleanliness. This is particularly important in preventing cross-contamination and ensuring that products remain free from contaminants.

Cost Savings Over Time

While the initial investment in a lotion filling machine may be significant, the long-term savings can be substantial. By reducing product waste, minimizing labor costs, and increasing production efficiency, these machines can lead to considerable cost savings over time. Additionally, the enhanced consistency and quality can reduce the need for costly rework or product recalls, further contributing to financial benefits.

Conclusion

In the competitive world of personal care and cosmetics, the benefits of lotion filling machines are undeniable. From ensuring precise filling and consistent quality to enhancing efficiency and safety, these machines play a crucial role in modern manufacturing processes. By investing in advanced lotion filling technology, manufacturers can improve product quality, streamline operations, and ultimately deliver a superior experience to their customers.

If you’re looking to elevate your production capabilities and maintain the highest standards, considering an upgrade to a high-quality lotion filling machine might be the next step towards achieving your business goals. Source: https://autopackmachinespvtltd.wordpress.com/2024/07/27/enhancing-quality-and-consistency-benefits-of-lotion-filling-machines/

[learning-robotics]

What types of machine learning algorithms are used in solving some popular real-world problems

Machine learning (ML) algorithms are used in various real-world applications to solve complex problems. Here are some of the popular types of machine learning algorithms and the real-world problems they address:

1. Supervised Learning Algorithms

These algorithms learn from labeled data and make predictions based on that data.

a. Linear Regression

Use Case: Predicting house prices.

Description: This algorithm predicts a continuous value. For example, given historical data on house prices, linear regression can predict the price of a new house based on its features (e.g., size, location, number of bedrooms).

b. Logistic Regression

Use Case: Spam detection in emails.

Description: This algorithm predicts a binary outcome (e.g., spam or not spam). Logistic regression is used to classify emails into spam or non-spam based on features like word frequency and sender information.

c. Decision Trees

Use Case: Customer segmentation. 

Description: Decision trees split the data into subsets based on feature values, creating a tree-like model. This can be used to segment customers based on their purchasing behavior to target them with personalized marketing.

d. Support Vector Machines (SVM)

Use Case: Image classification. 

Description: SVMs find the hyperplane that best separates different classes in the data. For instance, they can be used to classify images of cats and dogs based on pixel values.

2. Unsupervised Learning Algorithms

These algorithms find hidden patterns or intrinsic structures in input data without labeled responses.

a. K-Means Clustering

Use Case: Market basket analysis. 

Description: K-means clustering groups similar data points together. Retailers use it to understand customer purchase behavior and group similar items together for better inventory management.

b. Principal Component Analysis (PCA)

Use Case: Facial recognition. 

Description: PCA reduces the dimensionality of the data, making it easier to analyze. It’s used in facial recognition systems to identify the key features of faces for accurate identification.

3. Reinforcement Learning Algorithms

These algorithms learn by interacting with an environment and receiving feedback in the form of rewards or penalties.

a. Q-Learning

Use Case: Game playing. 

Description: Q-learning is a model-free reinforcement learning algorithm. It’s used in developing AI agents that play games (e.g., AlphaGo), where the agent learns the best actions to take to maximize its score.

b. Deep Q-Networks (DQN)

Use Case: Autonomous driving. 

Description: DQNs combine Q-learning with deep neural networks. They are used in self-driving cars to navigate and make decisions in complex environments.

4. Neural Networks and Deep Learning

These algorithms are inspired by the structure and function of the human brain.

a. Convolutional Neural Networks (CNNs)

Use Case: Medical image analysis. 

Description: CNNs are designed for processing structured grid data like images. They are used in medical diagnostics to analyze X-rays, MRI scans, and other medical images for detecting diseases.

b. Recurrent Neural Networks (RNNs)

Use Case: Language translation. 

Description: RNNs are used for sequential data. They are employed in natural language processing tasks such as translating text from one language to another (e.g., Google Translate).

5. Ensemble Learning Algorithms

These algorithms combine multiple models to improve performance.

a. Random Forest

Use Case: Fraud detection. 

Description: Random forests combine multiple decision trees to improve accuracy. They are used in banking and finance to detect fraudulent transactions based on transaction patterns.

b. Gradient Boosting Machines (GBMs)

Use Case: Predictive maintenance. 

Description: GBMs build models sequentially to correct errors made by previous models. They are used in predictive maintenance to forecast equipment failures and schedule timely maintenance.

Conclusion

Machine learning algorithms are crucial in solving a wide range of real-world problems, from predicting prices and detecting fraud to diagnosing diseases and enabling self-driving cars. The choice of algorithm depends on the nature of the problem, the type of data available, and the specific requirements of the application.

[bhavanameti]

Food Packaging Equipment Market Poised to Achieve $25.37 Billion

Meticulous Research® - a leading market research company, published a research report titled “Food Packaging Equipment Market by Type (Form-fill-seal Equipment, Cartoning Equipment, Filling & Dosing Equipment, Wrapping & Bundling Equipment, Case Packing Equipment), Application, and Geography - Global Forecasts to 2029”.

The Food Packaging Equipment Market is poised for substantial growth, with an anticipated CAGR of 6% from 2022, projecting to reach $25.37 billion by 2029. In terms of volume, the market is expected to expand at a CAGR of 8% during the same period, reaching 12,131.3 thousand units by 2029. This growth is primarily driven by the increasing integration of automated technologies, machinery flexibility, and the rising demand for hygienic food packaging. Additionally, food manufacturers are increasingly inclined towards using efficient packaging products.

Emerging economies experiencing a surge in the packaged food industry and the use of packaging as a tool for product differentiation present significant growth opportunities for market players. However, challenges persist, including the high cost of advanced packaging solutions and stringent environmental regulations. Recycling complexities of multilayer films and a scarcity of skilled personnel further impede market growth.

The global food packaging equipment market is segmented based on type, application, and geography, with an in-depth analysis of industry competitors and country-level market assessment. The types of equipment include form-fill-seal, cartoning, filling & dosing, wrapping & bundling, case packing, labeling & coding, inspecting, detecting, and checking weighing machines, among others.

In 2022, form-fill-seal equipment is expected to dominate the market, particularly due to the speed and versatility it offers, streamlining packaging processes. This segment includes both vertical and horizontal form-fill-seal equipment, with the former accounting for a larger share due to its suitability for automated assembly-line packaging systems.

Application-wise, segments such as meat, poultry, and seafood are anticipated to hold significant market shares, driven by increased consumption of processed and frozen products. Geographically, Asia-Pacific is expected to lead the market, owing to rising packaged food applications and a high concentration of local packaging equipment manufacturers.

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The key players profiled in the food packaging equipment market are Syntegon Technology GmbH (Germany), Coesia S.P.A (Italy), GEA Group Aktiengesellschaft (Germany), MULTIVAC Group (Germany), IMA Group (U.S.), Krones AG (Germany), Tetra Laval Group (Switzerland), OPTIMA Packaging Group GmbH (Germany), ARPAC LLC (U.S.), Ishida Co. Ltd (Japan), Omori Machinery Co. Ltd. (Japan), and TNA Solutions Pty Ltd. (Australia).

Key Questions Answered in the Report:

Which are the high-growth market segments in terms of type, application, and geography?

What is the historical market size for global food packaging equipment across the globe?

What are the market forecasts and estimates for the period 2022–2029?

What are the major drivers, restraints, opportunities, and challenges in the global food packaging equipment market?

Who are the major players in the market, and what are their market shares?

How is the competitive landscape for the global food packaging equipment market?

What are the recent developments in the global food packaging equipment market?

What are the different strategies adopted by the major players in the market?

What are the key geographic trends, and which are the high-growth countries?

Who are the local emerging players in the global food packaging equipment market, and how do they compete with other players?

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[tmr-blogs2]

Plasmonic Materials Market to reach US$ 39.4 Billion by 2031

The global plasmonic materials market would be worth US$ 10.7 billion in 2022. The same market is expected to reach US$ 39.4 billion by 2031, rising at a rapidly increasing CAGR of 15.5% from 2023 to 2031. Plasmonic nanoparticles, which include silver, gold, and platinum particles, are isolated metallic particles that, as a result of their size and shape, exhibit special optical properties.

These particles are being used more often in industrial goods and technology. These technologies make use of the amazing effectiveness of plasmonic nanoparticles in the absorption and dispersion of light. Their applications range from photovoltaics to physiological and chemical sensors. Furthermore, unlike the majority of pigments and dyes, plasmonic particles have a color that is dependent on their shape and size and can be tuned to enhance the performance for specific applications without altering the chemical attributes of those material.

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Another crucial aspect of these materials is surface plasmon resonance. Since they are more affordable, label-free detection methods are becoming more and more popular than labeled ones. Another key aspect that will increase demand for surface plasmon resonance is the availability of flexible goods combined with it to improve the specificity of testing.

Market Segmentation:

By Service Type: Materials Synthesis, Characterization, Consulting Services

By Sourcing Type: In-house, Outsourced

By Application: Sensors, Imaging, Energy Harvesting, Others

By Industry Vertical: Electronics, Healthcare, Energy & Environment, Defense & Security, Others

By Region: North America, Europe, Asia Pacific, Latin America, Middle East & Africa

Regional Analysis:

North America: Leading the market due to extensive research activities and strong presence of key market players.

Europe: Witnessing substantial growth owing to investments in nanotechnology and increasing adoption across industries.

Asia Pacific: Emerging as a lucrative market with rapid industrialization, technological advancements, and growing demand for innovative solutions.

Market Drivers and Challenges:

Drivers:��Technological Advancements, Increasing Demand in Healthcare and Electronics, Growing Investments in R&D.

Challenges: High Cost of Materials, Regulatory Hurdles, Limited Awareness in Developing Regions.

Market Trends:

Nanocomposites: Integration of plasmonic materials into nanocomposites for enhanced functionalities.

Biomedical Applications: Utilization in biosensors, drug delivery systems, and medical imaging.

Energy Sector: Innovations in solar cells, catalysis, and energy-efficient devices.

Future Outlook: The future of the plasmonic materials market looks promising, with ongoing research likely to unlock new applications and drive market growth. Investments in sustainable materials and technological advancements will further propel market expansion.

Key Market Study Points:

Materials Synthesis Techniques: Nanoimprint Lithography, Chemical Synthesis, Physical Vapor Deposition.

Market Adoption: Key End-Use Industries, Emerging Applications, Regulatory Landscape.

Competitive Landscape: Key Players, Market Share Analysis, Collaborations, and Partnerships.

Recent Developments: Breakthroughs in Materials Design, Commercialization Efforts, Market Expansion Strategies.

Competitive Landscape: Major players in the plasmonic materials market include Nanoscribe GmbH, NanoOpto Corporation, Cytodiagnostics Inc., Nanospectra Biosciences Inc., and more. Competition is intense, with companies focusing on product innovation, strategic partnerships, and geographical expansion to gain a competitive edge.

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Recent Developments:

Nanoscribe GmbH introduced a novel plasmonic material with enhanced light-matter interactions for advanced photonics applications.

NanoOpto Corporation partnered with a leading electronics manufacturer to integrate plasmonic materials into next-generation display technologies.

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Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.

Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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[amey-inkwood]

Industrial Robotics Market: How Cobots are Transforming Automation

The global industrial robotics market is revolutionizing with a surge in automation demand across industries, stimulated by cost efficiency and advancements in technologies like AI and collaborative robotics. Cobots, or collaborative robots, stand out in industrial robotics with their unique design and functionality for human interaction in a defined workspace. According to Inkwood Research, the global industrial robotics market was valued at $xx million in 2023 and is expected to reach $xx million by 2032, growing at a CAGR of 12.4% during the forecast period 2024-2032.

Collaborative robots, distinct from traditional robots, shine in collaborative tasks with humans, offering a cost-effective solution for small and medium-sized enterprises. Versatile, easy to program, and equipped with sensors, cobots redefine automation by promoting seamless interaction, user-friendly interfaces, and enhanced workplace safety.

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Real-World Applications of Cobots: From McDonald’s to Doosan Robotics

Businesses like McDonald’s are capitalizing cobots in their outlets for automated operations, incorporating ATM-style cash and credit card dispensers to streamline customer transactions.

Manufacturers like ONExia integrate advanced cobots, such as Universal Robots’ UR20, into palletizing equipment like the PalletizUR 2.0. With a 20 kg handling capacity and user-friendly features, it streamlines case management without programming. It utilizes a touchscreen interface with drag-and-drop functionality for tasks like conveyor control and label orientation.

ABB Robotics joined forces with the University of Texas Medical Branch (UTMB) in February 2023 to address COVID challenges through the automation of neutralizing antibody tests for research and diagnostics. The robotic neutralizing antibody system speeds up detection—from 15 to over 1,000 tests per day and provides useful data for developing scalable and reliable methods to assess herd immunity against various COVID strains.

Doosan Robotics, a manufacturer of collaborative robots, introduced E-SERIES in April 2023, a range of collaborative robots certified by NSF that is designed especially for the food and beverage industry.

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Industrial Robotics Market: Major Players and Ongoing R&D Innovations

Major market participants such as Kawasaki Heavy Industries Ltd, ABB Ltd, Universal Robots, and smaller companies like Techman Robot, producing cobots for small businesses, consistently partake in research and development to enhance cobot offerings in an effective and economical.

Strategic Diversity Among Market Participants:

ABB introduced two new variations of its GoFa collaborative robot range in June 2023, GoFa 10 and GoFa 12. These cobots are simple to program and deploy, and they can handle payloads weighing up to 10 and 12 kg with repeatability, encouraging first-time users and SMEs to automate. 

Xaba, in June 2023, collaborated with Lockheed Martin, a global security and aerospace company. The collaboration aimed to automate manufacturing by integrating industrial robots with Xaba’s xCognition deep artificial neural network model. Test results showed a 10X improvement in accuracy and consistency, emphasizing the substantial potential of industrial robotics to transform diverse industries.

Collaborative Robotics secured $30 million in Series A funding, utilizing it to scale deployments and manufacture innovative cobots. Moreover, the team introduced the Cobot Flywheel Program to aid companies in biotech, healthcare, and logistics in achieving operational transformation through advanced robotics solutions.

The Danish cobot maker Universal Robots unveiled the UR30 in November 2023, a new cobot with a 30 kg payload capacity. The compact UR30 boasts exceptional motion control, enabling it to handle heavy loads with precision and operate at high speeds. This versatility makes it perfect for tasks like material handling, machine tending, and high-torque screw driving.

At the Tokyo International Robot Exhibition (iREX) in November 2023, Techman Robot, a manufacturer of collaborative robotic arms, debuted the TM AI Cobot TM25S. The TM25S, part of the TM Robot family and TM AI Cobot S Series, incorporates a 3D camera and integrated smart vision. With an impressive 25 kg payload capacity, it excels in precision-demanding tasks such as AI-driven mixed-case depalletizing.

The cobot market is set to advance with technology. Anticipated trends in Industry 4.0 include increased intelligence, improved sensing, and better integration with existing smart manufacturing. Advances in sensor tech will enhance cobots’ understanding of their surroundings, improving efficiency across various industries.

Cobots represent a significant advancement in the field of industrial robotics market, offering a collaborative and safer approach to automation that is in line with the changing demands of the modern market. As artificial intelligence and machine learning reshape the sphere of industrial robotics globally, collaborative robots with intelligence and advancement are anticipated to propel industrial robotics market growth during the forecasting years.

FAQ

How do collaborative robots differ from cooperative robots?

Collaborative robots (cobots) and cooperative robots both involve human-robot interaction. Collaborative robots can work directly with humans in a shared location, adapting to their actions in real time. Cooperative robots, on the other hand, frequently collaborate with people but may require predefined, coordinated activities that do not allow for real-time adaptation.

What is driving the demand for the industrial robotics market?

Rising demand for industrial robots is fueled by several factors such as labor shortages and costs pushing automation, robots boosting production efficiency and quality, advancements making them smarter and adaptable, and companies reshoring production and strengthening supply chains through robot reliance.

How do industrial robots enhance operational efficiency?

Industrial robots enhance operational efficiency by automating repetitive tasks, reducing labor costs, and improving precision. Their ability to work continuously contributes to increased productivity in manufacturing processes.

[warmfrontt]

Help With A New Boiler: Choosing, Installing, and Maximizing Efficiency

A reliable and efficient boiler is an essential part of any home, providing warmth and hot water for daily activities. However, when the time comes to replace an old or faulty boiler, the process can be overwhelming. With the wide variety of options available on the market, homeowners often seek guidance to make the best choice for their needs. In this article, we will explore the key aspects of acquiring a new boiler, from selecting the right model to ensuring optimal installation and maximizing energy efficiency.

Assessing Your Requirements: Before embarking on the journey of purchasing a new boiler, it is crucial to assess your requirements. Consider factors such as the size of your property, the number of occupants, and the demand for hot water. This evaluation will help determine the appropriate size and capacity of the boiler needed to meet your household's heating and hot water needs.

Choosing the Right Boiler: With various types of boilers available, such as combi boilers, system boilers, and regular boilers, it is essential to select the right one for your home. Combi boilers, for example, are compact and efficient, providing both heating and hot water without the need for a separate storage tank. System boilers are suitable for larger properties with multiple bathrooms, while regular boilers are ideal for homes with traditional heating systems. Consulting a qualified heating engineer or a boiler specialist can provide valuable insights into selecting the most suitable boiler type for your specific requirements.

Professional Installation: Installing a new boiler requires technical expertise, and it is always recommended to enlist the services of a professional heating engineer or a registered installer. These experts will ensure that the boiler is correctly connected to the existing heating system, water supply, and gas or electricity sources, adhering to all safety regulations. Proper installation guarantees optimal performance, efficiency, and longevity of your new boiler.

Energy Efficiency and Cost Savings: Investing in an energy-efficient boiler can lead to substantial long-term cost savings while reducing your carbon footprint. Look for boilers with high energy efficiency ratings, typically indicated by an ErP (Energy-related Products) label. Boilers with a higher ErP rating tend to have lower energy consumption, resulting in reduced utility bills. Additionally, consider features such as smart thermostats and programmable controls, which enable better control over your heating system, maximizing energy efficiency and comfort.

Regular Maintenance and Servicing: To keep your new boiler operating at its best, regular maintenance and servicing are crucial. Schedule annual inspections by a qualified professional to ensure optimal performance, detect any potential issues early on, and extend the lifespan of your boiler. Regular servicing also helps maintain the manufacturer's warranty, providing peace of mind in case of unforeseen breakdowns.

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[optopixel]

The Importance of Visual Inspection in the Pharmaceutical Industry

Maintaining the standards in the pharmaceutical industry is paramount. Visual inspection is an essential part of the pharmaceutical manufacturing process. It plays a crucial role in ensuring product quality, safety, and efficacy. The pharmaceutical industry needs to follow stringent guidelines and regulations to ensure that the products are of the highest quality and as per the defined standards and parameters. Visual inspection is one such critical quality that falls under quality control measures.

Why is visual inspection important in the pharmaceutical industry?

Visual inspection plays an integral role in matching up with industry standards. Here are some of the key reasons why every pharmaceutical company should focus on visual inspection of the entire manufacturing process:

Detecting physical defects

The visual inspection helps in identifying any physical defects in the drug product, such as cracks, chips, or discolouration. These defects can affect the quality and safety of the product. Consequently, it impacts the overall brand image and may draw legal penalties. But with stringent visual inspection practices, companies can easily detect the problem area and overcome the same before releasing the medicine in the market.

Ensuring label accuracy

Apart from detecting the quality of medicine, the visual inspection also includes a screening of product labels. In addition, it involves checking whether or not the labelling is accurate and meets the regulatory requirements. This includes checking that the correct drug name, strength, and dosage form are listed on the label.

Monitoring packaging integrity

Visual inspection is used to ensure that the packaging of the drug product is intact and free from any damage or tampering. This is important as damaged packaging can compromise the integrity of the product and reduce its shelf life.

Ensuring product consistency

Every drug product should look consistent in terms of its appearance, size, and shape. The visual inspection ensures that each dose of the product contains the correct amount of active ingredients and delivers the expected therapeutic effect.

Meeting regulatory requirements

Every pharmaceutical company needs to comply with industry standards and quality parameters. Failing to do so attracts several legal penalties. With a visual inspection, companies can easily figure out the concerning areas, thus ensuring that the final product is of the best quality and matches the parameters specified by the authorities.

Identifying the bottlenecks

By using visual inspection, pharmaceutical companies can also identify areas where improvements can be made in their production process. It helps in identifying the root cause of defects or inconsistencies in the product. This enables them to make necessary adjustments and improvements. Thus, ensuring that the final product is of the best possible quality and matches the parameters specified by regulatory authorities.

The future of Visual Inspection for quality testing in pharmaceuticals

The intervention of technology in the pharma sector plays an important role in enhancing the overall efficiency of the process. Here are some trends that are likely to shape the future of visual inspection in the pharmaceutical industry:

Increased Automation

There is a growing trend towards increased automation in the pharmaceutical industry, including a visual inspection. Automated inspection systems can provide faster and more consistent results than manual inspection while also reducing the risk of errors and contamination.

Artificial Intelligence and Machine Learning

These technologies can be used to analyze large amounts of data from visual inspection systems, enabling faster and more accurate identification of defects or anomalies. AI and machine learning can also improve the performance of automated inspection systems over time by learning from past inspection results.

Advanced Imaging Technologies

The use of advanced imaging technologies, such as hyperspectral imaging or terahertz imaging, enables an accurate inspection of products than is currently possible. These technologies can also help to detect defects that may be invisible to the naked eye.

Integration with other Quality Control Systems

Visual inspection systems may become more integrated with other quality control systems, such as particle analysis or chemical analysis, to provide a more comprehensive picture of product quality.

Regulatory Requirements

Regulatory requirements for visual inspection in the pharmaceutical industry are likely to become more stringent in the future, requiring greater accuracy and consistency in inspection results. This may drive further innovation in visual inspection technologies.

Wrapping It Up!!!

The future of visual inspection for quality testing in pharmaceuticals will undergo transformation.  Automation, integration with other quality control systems, and the use of advanced imaging technologies will play a pivotal role in this. These trends are likely to enable faster, more accurate, and more reliable inspection of pharmaceutical products. Thus, helping to ensure their safety and efficacy.

Source : https://optopixel.com/the-importance-of-visual-inspection-in-the-pharmaceutical-industry/

[medicalnewstoday]

Label Free Detection Systems Market World Analysis And Forecast Research Report – 2020

Drug discovery market is growing at a significant rate due to high investments from pharmaceutical companies and academic institutes in R&D of innovative products. Drug delivery processes involve target identification and screening of drugs. Label-free detection systems refer to the integrated systems that investigate about the biomolecular interactions without quenching of labels or auto-fluorescent effects. These systems provide rapid and real time approach for new drug discovery. Label-free detection systems may be used to detect both biochemical and cell-based assays. High acceptance rate for the use of this technology in pharmaceutical and biotechnology sector due to various advantages involved with the process are driving the global label-free detection systems market. On the basis of applications, label-free detection systems market may be segmented into binding thermodynamics, hit confirmation, binding kinetics, lead generation, endogenous receptor detection and others. Out which binding kinetics segment has the largest market.

On the basis of technology used, surface plasmon resonance technology segment has the largest share in the global label-free detection systems market. However, bio-layer interferometry segment is expected to grow at the fastest rate. This is due to less fluctuation in the refractive index of the samples being tested and microfluidic-free nature of bio-layer interferometry label-free detection systems. North America dominates the global label-free detection systems market due to technological advancement and high government funding in the region.

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Europe followed by Asia is expected to experience high growth rate in the next few years in global label-free detection systems market. Some of the key driving forces for label-free detection systems market in emerging countries are increasing R&D investment, large pool of patients and rising government funding.

Increased R&D investments in drug discovery from various pharmaceutical and biotechnology companies, rising government funding and growing number drug discovery programs by various academic institutions is driving the global label-free detection systems market. However, high cost involved and increasing consolidation of pharmaceutical and biotechnology companies are restraining the growth of global label-free detection systems market.

Increasing adoption rate for label-free technology in various industries is expected to offer good opportunity for growth of label-free detection systems market. In addition, advancement in the features offered in label-free detection systems, such as lower analysis time and higher sensitivity is expected to drive the label-free detection systems market. Some of the key trends that have been observed in label-free detection systems market are major companies dealing in label-free detection market involved in expanding their geographical presence and new product launches with innovative technologies.

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Some of the major companies dealing in label-free detection systems market are

Bio-Rad Laboratories

General Electric Corporation

Corning

PerkinElmer Inc.

SRU Biosystems

X-BODY Biosciences

Other market players with significant presence are:

CSEM (Centre Suisse d’Electronique et Microtechnique SA)

BiOptix

AMETEK

Attana AB

Danaher Corporation

Pall Corporation

F. Hoffmann-La Roche Ltd.

[techsciresearch]

Vietnam Cybersecurity Market to grow at a CAGR of 16.52% until 2026 – TechSci Research

Growing demand for digital services in the public and private sector is driving the growth of Vietnam Cybersecurity Market.

According to TechSci Research report, “Vietnam Cybersecurity Market, By Security Type (Network Security, Application Security, Cloud Security, Endpoint Security, Content Security & Others), By Solution Type (Firewall, Antivirus & Anti Malware, Risk & Compliance Management, Identity & Access Management, Unified Threat Management, Data Loss Prevention, Encryption & Decryption, Intrusion Detection/Prevention System, Infrastructure Security & Others), By Deployment Mode (Cloud & On premise), By End-User Industry (BFSI, IT & Telecom, Retail, Government & Defense, Healthcare, Education Technology & Others), By Region, By Top 10 Provinces, Competition, Forecast & Opportunities, 2016-2026”, the Vietnam Cybersecurity Market is forecast to grow at a rate of 16.52% to reach USD350.48 million by 2026. Growth in the market can be attributed to the leaning of the Vietnamese government towards investigating, detecting and prosecuting cybercrimes in the last few years. Vietnam has been ranked 25th out of 182 countries in Global Cyber Security Index (GCI) 2020 by the International Telecommunication Union – the United Nation’s ICT-specialized agency. Cybersecurity Market has been primarily influenced by the massive potential of cloud services in Vietnam. The National Assembly of Vietnam has adopted the Law on Cybersecurity (“LCS”) that aims to protect national security and ensure social order and safety in cyberspace. This law will act as a catalyst for adoption of cybersecurity by various enterprises. According to the National Cyber Security Centre (NCSC) of the Vietnam Authority of Information Security, in 2020, more than 90% of the cybersecurity products and services were made in Vietnam.

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" Vietnam Cybersecurity Market "

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The Vietnam Cybersecurity Market is segmented by security type, by solution type, by deployment mode, by end-user industry and by region. In terms of security type, the market can be segregated into Network Security, Application Security, Cloud Security, Endpoint Security, Content Security and Others. Out of these, the network security segment registered a dominant market share in 2020. The network security is dominating the Vietnam Cybersecurity Market as it is one of the most important aspects to consider when working over the internet or the cloud. Moreover, robust network security systems help businesses reduce the risk of falling victim to data theft. Implementing network security solutions allows computers, users, and programs to perform their permitted critical functions within a secure environment.

Based on solution type, the market is segmented into Firewall, Antivirus & Anti Malware, Risk & Compliance Management, Identity & Access Management, Unified Threat Management, Data Loss Prevention, Encryption & Decryption, Intrusion Detection/Prevention System, Infrastructure Security, Others. Out of these, firewall solutions dominated the Vietnam Cybersecurity Market in 2020 as these solutions provide protection against outside cyber attackers by shielding the device or network from malicious or unnecessary network traffic.

Based on deployment mode, the Vietnam Cybersecurity Market is bifurcated into Cloud & On-premise. Cloud dominated the market as the cloud computing technology is being widely adopted by the country. According to the Ministry of Information and Communications, in recent years the cloud computing market has been growing at 30 percent on average, and in 2020 the growth rate reached 40 percent due to the COVID-19 pandemic.

In terms of end-user industry, the market is segmented into BFSI, IT & Telecom, Retail, Government & Defense, Healthcare, Education Technology, Others. The BFSI industry dominated the Vietnam Cybersecurity Market in 2020. Digital transformation of banking sector has changed the consumer buying behavior with preference for online shopping. The banking firms are investing aggressively into cybersecurity in quest to protect the customers’ personal information, passwords, and financial information from cybercriminals.

Viettel Cyber Security Company, FPT Corporation, CMC Cybersecurity, IBM Vietnam Company Ltd., HPT Vietnam Corporation, Microsoft Vietnam Limited Liability Company, Amazon Web Services Vietnam Company Limited, SAP Vietnam Co. Ltd., Vietnam Posts and Telecommunications Group, Salesforce.com, Inc., Cisco Systems, Inc., CrowdStrike Holdings, Inc., FireEye, Inc., McAfee LLC, Accenture, Inc. etc. are among the leading players operating in the Vietnam Cybersecurity Market. Companies operating in the market are using organic strategies, partnerships and collaborations to boost their shares in the Vietnam Cybersecurity Market. Significant players in the market are concentrating on accomplishing ideal operational expenses, upgrading the system efficiency, enhancing precision in responses, boosting productivity with high funding in R&D, and merging with small players to support the competitive Vietnam Cybersecurity Market.

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 “The digital transformation of the country including e-Government, e-business, and an e-society will drive the growth of the Vietnam cybersecurity market. Moreover, the passing of the “Law on Cybersecurity” in 2018, has encouraged Vietnamese firms that use advanced technologies and solutions to invest in cybersecurity which has led to the development of ecosystem of 'Make in Vietnam' cybersecurity products. This growing awareness of the consumers towards cyberattacks and regulatory measures being taken by the government to protect the cyberspace is expected to act as a catalyst for the Vietnam Cybersecurity Market.” said Mr. Karan Chechi, Research Director with TechSci Research, a research-based global management consulting firm.

“Vietnam Cybersecurity Market, By Security Type (Network Security, Application Security, Cloud Security, Endpoint Security, Content Security & Others), By Solution Type (Firewall, Antivirus & Anti Malware, Risk & Compliance Management, Identity & Access Management, Unified Threat Management, Data Loss Prevention, Encryption & Decryption, Intrusion Detection/Prevention System, Infrastructure Security & Others), By Deployment Mode (Cloud & On premise), By End-User Industry (BFSI, IT & Telecom, Retail, Government & Defense, Healthcare, Education Technology & Others), By Region, By Top 10 Provinces, Competition, Forecast & Opportunities, 2016-2026” has evaluated the future growth potential of cybersecurity in Vietnam Cybersecurity Market and provides statistics and information on market structure, size, share and future growth. The report is intended to provide cutting-edge market intelligence and help decision makers take sound investment decisions. Besides, the report also identifies and analyzes the emerging trends along with essential drivers, challenges and opportunities present in Vietnam Cybersecurity Market.”

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[dippedanddripped]

In the first few moments of a YouTube video titled “Admitting I Own Fakes In-Front of My Fashion Class…”, Quentin Caruso, better known as Tripping, does just that. “I’m a sophomore in college and I’m taking a class about fashion, and in that class (we) were talking about fakes and replicas,” he explains, adding that he can “throw up some pictures so you guys know I’m not bullshitting”. Asked by his teacher if he knowingly owns any counterfeit pieces, the 19-year-old confirms the sneakers he’s wearing at that very moment – the highly coveted Travis Scott Jordan 1 Lows – are in fact fake. “And how do you feel about that,” she prompts. “I’m fine with it,” he wryly confirms.

Caruso is part of a growing community of fashion-savvy shoppers searching for ways to look runway ready on a high street budget – and, unlike many die-hard hypebeasts, they’re willing to own up to the fact their luxury garms aren’t exactly legitimate. In fact, many take pride in their ability to score a bargain, taking to subreddit FashionReps to discuss new releases, fawn over faux Yeezys, and ask each other for advice on where to pick up the best knock-off Off-White and Supreme styles.

The forum is a democratised, judgement-free zone in which people share a love of high quality replicas or ‘reps’, where members are friendly and even supportive. They help one another to find the best sellers and sites to buy from, while discussing discrepancies between retail items and their counterfeit counterparts – from stitching and logos, to details and finishes. Most users admit they can’t afford head-to-toe designer looks, and at times they even share budgeting tips. "I got into reps cause I didn’t have much money and wanted a few nice pieces," redditor godsip2 shared in August. "Now I have no money at all 'cause I'm addicted to buying reps and can't stop myself."  

While a lack of funds and a taste for luxury streetwear is a driving factor for many, for others it isn’t about the money at all. “Not to brag, but if I want a Dior coat, I can get it retail,” Dennis, 19, tells us. “For the same (amount of) money I can get four reps.” Dennis admitted his breaking point came after a shocking moment browsing resale markets where he saw his ‘grail shoes’ – a pair of Off-White Air Jordan 1s – show up for €3000. “I thought ‘Fuck this, I’m never gonna pay that for shoes that originally retailed for €150.”

It’s been almost three years since he came across the FashionReps subreddit, which he was initially skeptical of. However, since joining he hasn’t just sworn off resale products and full-price retail items, but also introduced his friends to reps. “A €500 sweater wasn’t in their price range,” says Dennis. “When I showed them my reps (compared to) my retail Yeezys, they were instantly sold.”

Historically, counterfeit designer items conjure thoughts of poorly imitated handbags on AliExpress, labels that read, ‘Fashing BALISG’ instead of Balenciaga, and stalls in alleyways, but FashionReps members know where the quality replicas are sold and claim that many knock-offs actually tend to be better made.  “The quality is the same, even better,” Netherlands-based 23-year-old Camiel admits. “I’ve heard of some Yeezys being better and a lot of high-end Louis Vuitton reps being way better than retail.” He believes that “retail Louis Vuitton quality is not so great…”

FashionReps members buy in bulk, spending hundreds of dollars on ‘hauls’ that they break up into smaller packages in hopes of evading customs checks. The risk is part of the thrill, and while some are unlucky and have their packages seized, others rejoice when packages filled with thousands of dollars of ‘drip’ arrive in the mail.

Camiel cites his favourite find to be a Palace red slub-neck, “which you can't tell apart from a real one – which I have one of,” he adds. “The quality is amazing and it's super comfortable to wear, it's my favourite (item) I have gotten so far.” But Camiel hasn’t always gotten away with his thrifty finds.

“In the beginning, I wouldn't wear an item if it had the tiniest flaw. Later on, I noticed that people know (very) little about brands and which items even exist,” he explains. While most people who recognise a rep are likely to ask for the seller or pass on a compliment, Camiel concedes he’s been called out before. “Some high schoolers were at the gym and I was wearing my Nike tech fleece joggers, which have some noticeable flaws, like the black stripe being too short and the cords being too short as well. They called me out on the logo, which I know is perfect. Bunch of clowns.”

For all the people excited about reps, their quality, and believability, there are just as many people out there looking to spot a fake. YeezyBusta, who recently gained prominence for spotting fakes on civilians and celebrities has over 760,000 followers on Instagram. He’s busted the likes of Lil Tjay, Blac Chyna, and Soulja Boy for donning fake Supreme and Yeezys, although his faux-detector has been known to malfunction.

"I got into reps cause I didn’t have much money and wanted a few nice pieces. Now I have no money at all 'cause I'm addicted to buying reps and can't stop myself" – godsip2, FashionReps member

In an episode of Complex’s Full Size Run, hosts tasked the Instagram detective with discerning the difference between fake pairs of shoes from the real thing. After being handed a pair of bone-white Yeezy 500s, YeezyBusta exclaims, “Oh these are real!” Closely inspecting the shoe, he notices “The suede is right…even down to the stitching, the label inside the shoe looks right to me and the insole is right too.” The host, who finds it hard to hide his amusement, blurts out “They’re fake.” Behind his signature black surgical mask, used to hide his identity, YeezyBusta turns bright red.

“I can’t take him seriously,” Tripping admits. In a reaction video to a VICE documentary on YeezyBusta, the fashion student protests his motivation for hunting down counterfeit items so publicly. “It isn’t funny. Does anyone find that funny? To ridicule people online? That isn’t something you should be gloating about.”

Some counterfeit items are so believable that they’ve also slipped past trusted authenticators. The RealReal, one of the world's leading luxury consignment stores, claims that "every item we sell is 100% authenticated by an expert.” However, just last year, Forbes contributor, Richard Kentenbaum claimed the retail giant had sold him a fake Toile de Jouy Dior Book Tote bag for $3,600. What followed was a swift investigation by CNBC, who, after speaking with a dozen former employees and unsatisfied customers, and obtaining internal company documents, revealed that “many of the items on the site were being authenticated by copywriters with limited training.” and those who are doing this work are finding it increasingly difficult to spot counterfeits. Out of 1,400 reviews online for The RealReal, the top complaints are fake items.

It may come as a surprise to learn that this is something FashionReps also stands firmly against. In December, the group came together after Depopuser James’s Closet was spotted selling counterfeit items. Within a day, the subreddit had made efforts to liaise with Depop directly and reported the fake pieces resulting in all the listings being taken down. And this isn’t the only time the forum has rallied against people selling fake items moonlighting as cheap authentic ‘steals’. “People who willingly sell replicas as authentic items are the worst,” Tripping insists. “Knowing that a replica looks so close to retail and not selling it for a lot of profit is challenging for some people.”

Conversely, enjoying replicas as they are comes with its own baggage. Reports indicate that counterfeit fashion is a trillion-dollar industry. "One of the worst stories I read was where they had raided an illegal factory and the children were actually handcuffed to the sewing machines," Ariele Elia, an assistant curator at the Museum at FIT explained in a Complex documentary about the flourishing bootleg industry.

Fashion Revolution, a not-for-profit global movement campaigning for the systemic reform of the fashion industry, notes that there’s an “urgent lack of transparency.” Policy Director at Fashion Revolution, Sarah Ditty, told us that counterfeiting doesn’t usually come hand in hand with good rights and wages for workers. “Factories making counterfeit items are doing so illegally so it’s in their interest to operate completely under the radar and in doing so means we have no idea who the workers are making these products, what they are being paid, what conditions they’re working in, and what sort of poor environmental practices are most likely happening in these factories.”

To them, the moral standpoint is clear: “We would definitely encourage people not to buy fake luxury goods or any other counterfeit items because you’re almost guaranteed to be contributing to human exploitation and environmental degradation.” This is an issue that goes beyond fakes: when you look beyond the manufacturing level at the places where fabrics are made, yarns are spun and fibres are grown, even legitimate brands are guilty of obscuring working conditions.

But Tripping insists it's a media smoke-screen. “adidas and Nike were called out for their treatment of workers in the 90s and early 2000s, so now every factory in Asia is associated with bad conditions and child labour.” Tripping also claims that sellers are in fact increasingly transparent about working conditions, their treatment of employees and factories. “They show what their shop looks like, I’ve even asked sellers to show their shops,” he remarked in one of his videos. “And they’ve posted videos on the (subreddit).” One video posted shows a “top quality Yeezy” factory filled with workers. “Actually looks very clean and cool compared to all of the bad warehouse jobs I used to do here in the US,” Redditor highnnmighty comments.

“That’s like asking if I’ll ever go back to my ex, it was a fun time but in the end, you just feel shitted on” – Dennis, on whether or not he will stop buying fakes

Central to what makes FashionReps a great community isn’t the collective middle-finger to resale culture and hypebeasts or the internet-savvy tips, but the irreverent charm and supportive nature of young people who ultimately just want to look cool, and don’t want money to be the reason that they miss out. It’s rare, if not impossible, to find fashion spaces that aren’t hierarchical, based on wealth, social standing, and nepotism, but FashionReps manages to do all of that, and more. Camiel tells me that recently, the subreddit even banded together to target sellers who began taking higher cuts from sales. “I love how we sometimes work together to get something we want.”

Confronted with the fact that buying reps are taking sales away from workers, brands, and designers, Tripping is unfazed. “Once a limited shoe is released, and sold out in seconds, the company has made its profit. The average cost of manufacturing an Air Jordan 1 is $15-$16. The mark up of that shoe is more than 100 per cent. Nike has no problem with this. If you are wearing a replica of that overpriced shoe (on the resell market), you are basically advertising the brand. The culture side of sneakers is bland and fraudulent, replicas are there to stir things up.”

When asked if he’d ever give up replicas and return to buying retail, Dennis scoffed before saying: “That’s like asking if I’ll ever go back to my ex, it was a fun time but in the end, you just feel shitted on.”

[f107aquaticinvertebrates]

Predatory Snail (Conus)

*hehe will post our next blogpost on the account*

Group 3

I. Classification

Kingdom               Animalia Subkingdom         Bilateria Infrakingdom        Protosomia Superphylum       Lophozoa Phylum                Mollusca Class                   Gastropoda Subclass              Prosobranchia Order                   Neogastropoda Family                  Conidae Genus                  Conus

ITIS (n.d.)

II. Biology

Tropical Dwellers

Approximately, there are 700 Conus species. The majority is found throughout tropical and subtropical waters, such as the South China Sea, Australia, and the Pacific Ocean. Few species were found in South Africa, Southern Australia, Southern Japan, and Mediterranean Sea (Dutertre and Lewis, 2011). There are also existing species thriving in temperate waters such as C. californicus which are found in the North American Pacific coast(Gao et al. 2017).

Figure 1. Worldwide distribution of cone snails. Spot colors stand for various species number (Gao et al. 2017). Image retrieved from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744117/#B37-toxins-09-00397

Habitat

Cone snails are commonly found in intertidal and shallow sublittoral zones. They are present in coral reef areas, sand bottoms, and silty crevices. Some were reportedly found in mangrove areas, and in deeper waters of up to 400-600 meters (Carpenter and Niem, 1998; Dutertre and Lewis, 2011). 

Anatomy

Cone snails are gastropods. Gastropods have asymmetrical body symmetry and their shells are spirally coiled. Conus shells are cone-shaped. The spire of the shell is conical and moderately low to flat. It has a well-developed body whorl that tapers towards the narrow anterior end. The aperture is very long and narrow. There is a notch at the aperture’s posterior end, and a short, wide siphonal canal is located at the anterior end. The operculum is corneous, small, and ovate to claw-shaped. However, the operculum may not always be present (Carpenter and Angelis, 2016).

Figure 2. Ventral view of Conus shell with labelled parts.

Image retrieved from:http://www.fao.org/3/a-i5712e.pdf 

The soft body of gastropods has 4 main regions: the head, the foot, the visceral mass, and the mantle. The head protrudes from the anterior end. The foot is a muscular ventral organ with a flattened base used for locomotion (creeping or burrowing). The visceral mass is located in the spire of the shell and contains most organ systems. The mantle is a collar-like tegument which lines and secretes the shell and forms a mantle cavity normally provided with respiratory gills in aquatic species (Carpenter and Angelis, 2016).

Figure 3. Internal anatomy of Conus striatus.

Image retrieved from:https://www.marinelifephotography.com/marine/mollusks/gastropods/cones/cones.htm 

Cone snails have a specialized venom apparatus that comprises a venom gland, salivary glands, a radular sac, a pharynx, a proboscis, and a radula. The radula of the cone snail is hollowed and barbed and it resembles a harpoon. These harpoons are produced and stored in the radular sac, which is divided into two arms and connects to the pharynx. The short arm contains a few fully formed radula while the long arm is where the radulas are produced.

The cone snail uses chemosensory to detect prey. Once the prey is detected, it will extend its proboscis and shoot its radula which will inject a potent venom to paralyze its prey (Kohn et al. 1972; Marsh 1977; Salisbury et al. 2010; Schulz et al. 2004).

Images retrieved from:https://kristinabarclay.wordpress.com/2016/07/

Figure 4. Close-up photo of a cone snail’s radula (top). Cone snail radula under an electron microscope (bottom). 

Life Cycle

Most cone snail species have separate sexes and fertilization happens internally. Cone snails lay their eggs once a year. The egg masses of cone snails are usually made up of up to 25 egg capsules with each capsule containing roughly around 1000 eggs (Zehra & Perveen 1991). Two types of cone snail hatchlings have been described, the veliger stage (free-swimming larvae) and veliconcha stage (juvenile snails). During these stages, only a few will survive. In between 1 and 50 days, the snails will undergo the pelagic stage (Perron, 1983).

According to Rockel et al as cited in Dutertre and Lewis (2011), it is estimated that cone snails have a lifespan of 10-20 years. This estimated lifespan is based on the marks and shell growth of the snail. They can reach a maximum size of > 20 cm, but most species are < 8 cm  and weight < 100 g. 

Figure 5. Conus magus with egg sacs

Image retrieved from:https://poppe-images.com/?t=17&photoid=951805

Figure 6. Conus ammiralis with its egg capsules attached to Halimeda sp. algae.

Images retrieved from:http://www.underwaterkwaj.com/shell/cone/Conus-ammiralis.htm

III. Relationship with Humans

Cone snails are exploited for ornamental trade and research. 

Conus shells have economic value and are marketed as ornaments. One of the rarest and most valuable shells in the world is the Conus gloriamaris or the Glory of the Seas Cone (The Editors of Encyclopaedia Britannica 2020). 

Conantokins or sleeper peptides from the geographic cone snail are short chain peptides that can affect neural receptors in fish and mammals. This peptide has great potential that humans can benefit from when it comes to paint ecpetop, drug and alcohol withdrawal symptoms and learning. Con-G one of the conatokins from the geographic cone snail has been found to act as a neuroprotective agent in brain ischemia from strokes. Conus shells contain conotoxin which is used for drug development. For example, the ω-MVIIA (ziconotide) is a well-known conotoxin approved by the U.S. Food and Drug Administration (2004) to treat chronic pain in cancer and AIDS patients. It is derived from the toxin/venom produced by Conus Magus (Gao et al. 2017). Conus regius is rich in alpha-conotoxins, which can target nicotine receptors and can help in research concerning the development of medicine for Alzheimer’s disease, schizophrenia, lung cancer and even tobacco addiction. (Kompella et al. 2015)

Death by conus?

Humans can be negatively affected by conus. It is recorded that 30 humans have died from a conus sting. Once stung, the victim feels numbness accompanied by dizziness, slurred speech and respiratory paralysis and then death.

IV. Did you know?

1. The venom from one cone snail has a hypothesized potential of killing up to 700 people. (Kapil S., et al.)

2. The Geographic Cone Snail (Conus geographus), according to BBC Earth, is the most toxic cone snail in the world. Its venom contains a protein which when isolated scientists can be used as effectively as a morphine substitute without the harmful side effects. 

3. A person was recorded to be killed from a cone snail sting in as short as 5 minutes!

4. Some cone snails are solitary in nature, like the  Conus spurius or the Alphabet cone, and the only time individuals have contact with each other is during mating!

5. The largest Alphabet cone shell was recorded at 80 mm or as large as your regular sized mountain dew can!

6. Conus species were observed to exhibit “fishermen-like” behavior when hunting for food! They use their proboscis as lures and catch their prey, scientists even coined the term hook and line method to describe this hunting behavior, just like the fishing method.

7. The cone snail is the only recorded species in the animal kingdom to use insulin as a chemical weapon, a hormone that is also used to help diabetic people! Even though this is used as a means to catch prey, scientists actually used insulin from the cone snail’s venom and combined it with human insulin creating a new type of insulin called mini-Ins. 

IV. References

Chivian, E., et. al. (2003, November). The Threat to Cone Snails. Retrieved October 3, 2020 from: https://www.researchgate.net/publication/9046809_The_Threat_to_Cone_Snails_1

Gao B, Peng C, Yang J, Yi Y, Zhang J & Shi Q. 2017. Cone Snails: A Big Store of Conotoxins for Novel Drug Discovery. 2017; 9(12): 397. DOI: 10.3390/toxins9120397

Geography Cone. (2018, September 21). Retrieved October 3, 2020, from https://www.nationalgeographic.com/animals/invertebrates/g/geography-cone/

Hall, M. (n.d.). Conus geographus (geography cone snail). Retrieved October 3, 2020, from https://animaldiversity.org/accounts/Conus_geographus/

Kane, S. (2017, December 4). The most venomous animal on Earth is truly surprising. Retrieved October 3, 2020, from https://www.businessinsider.com/most-venemous-animal-cone-snail-2016-2?international=true&r=US&IR=T

Kohn, A.J. (2016). Human injuries and fatalities due to venomous marine snails of the family Conidae. DOI: 10.5414/CP202630 

Kompella SN, Hung A, Clark RJ, Mari F, Adams DJ. 2015. Alanine Scan of α-Conotoxin RegIIA Reveals a Selective α3β4 Nicotine Acetylcholine Receptore Antagoist. Journal of Biological Chemistry, 2015; 290(2): 1039 DOI: 10.1074/jbc.M114.605592 

Kohn, A.J. (2016). Human injuries and fatalities due to venomous marine snails of the family Conidae. DOI: 10.5414/CP202630 

Safavi-Hemami, J., et. al. (2014). Specialized insulin is used for chemical warfare by fish-hunting cone snails. Proc. Natl. Acad. Sci. U.S.A. 10.1073/pnas.1423857112 (2015).

Sygo, M. (1999). "Conus spurius" (On-line), Animal Diversity Web. Retrieved October 03, 2020 from https://animaldiversity.org/accounts/Conus_spurius/

The Editors of Encyclopaedia Britannica. 2020. Bugs, Mollusks & Other Invertebrates. Retrieved from https://www.britannica.com/animal/cone-shell

Xiong, X., Menting, J.G., Disotuar, M.M. et al.(2020). A structurally minimized yet fully active insulin based on cone-snail venom insulin principles. Nat Struct Mol Biol 27, 615–624 (2020). https://doi.org/10.1038/s41594-020-0430-8

[solusiprinting-blog]

What Is Graphic Design for Beginners?

When you consider graphic style, does one consider creative advertisements? Eye-grabbing graphics on websites? spectacularly organized spreads in magazines? whereas these examples actually match beneath the graphic style definition, the term encompasses a lot: posters, infographics, book covers, product labels, logos, business cards, signs, web site layouts, mobile apps, software system interfaces—the list goes on. So what's graphic style, exactly? Listing these graphic style examples may be a smart begin, however it doesn’t paint the total image. whereas covering the small print and intricacies of the whole graphic style field won't be potential in one article, this high-level summary can assist you higher perceive this inventive career field.

If you’re in any respect fascinated by turning into an expert graphic designer, keep reading to be told the fundamentals of the sphere.

What's Graphic Design?

graphic style is outlined as “the art and follow of designing and protrusive concepts and experiences with visual and matter content.” In alternative terms, graphic style communicates bound concepts or messages during a visual approach. These visuals is as easy as a business emblem, or as advanced as page layouts on an internet site. If you want know more detail about graphic design so you can see this site informasi desain grafis

“Graphic style takes graphical and matter parts and implements them into multiple forms of media,” says designer Alexandros Clufetos, once asked to elaborate on the graphic style definition. “It helps the producer connect with the patron. It conveys the message of the project, event, campaign or product.” Graphic style is utilized by firms to market and sell merchandise through advertising, by websites to convey sophisticated data during a light approach through infographics, or by businesses to develop associate identity through stigmatisation, among alternative things.

“Every day, we tend to take several of the subtly creative things around US without any consideration. however hidden in each magazine corner, exit sign or textbook lies a group of style concepts that influence our perceptions,” says Jacob Smith, founding father of illustration studio ProductViz. It’s conjointly necessary to recollect that though several graphic style comes have industrial functions like advertisements and logos, it's conjointly employed in alternative contexts and graphic style work is usually created strictly as a way for creative expression.

Graphic Style Basics

To better perceive the that means of graphic style, it's necessary to bear in mind of the weather and principles that structure style. parts area unit employed in conjunction or opposition with one another to form visually placing and impactful styles.

These graphic style parts include:

 ·         Color

·         Form

·         Line

·         Shape

·         Size

·         Space

·         Texture

Graphic styleers conjointly adhere to the principles of design, that area unit primarily a group of pointers that facilitate a style accomplish effective composition. These basic principles aid in making balance and stability for the piece of labor.

These graphic style principles include:

·         Balance

·         Contrast

·         Emphasis

·         Movement

·         Proportion

·         Rhythm

You’ve detected the previous voice communication that “rules area unit meant to be broken,” which might actually ring true during this case. however an honest graphic designer should initial perceive these principles before creating the acutely aware call to interrupt them.

Types of graphic style

As mentioned earlier, there's no single graphic style that means. Graphic style consists of the many fields and specializations, starting from print and internet style to animation and motion graphics. Graphic style offers opportunities and choices for people of just about any interest. If you’d asked somebody thirty years past to outline graphic style, their answer would have seemingly been targeted on print-related examples like magazines, picture show posters and advertisements. currently we’re living within the digital age, that has born to many new forms of graphic style.

Some of the foremost notable contemporary graphic style examples stem from advancements in technology. Here’s a glimpse of a number of these forms of graphic design: Website style involves making partaking and intuitive web content for users. This includes overall layout, combination and navigation.

User expertise (UX) style is targeted on guaranteeing an internet site or application is straightforward and satisfying to use. These designers emphasize price, usability, adoptability and desirability.

Motion graphics design or animation brings visual parts to life through camera work, TV shows, video games and flicks.

Common Graphic Style Jobs

With technological advancements introducing new forms of graphic style, there has conjointly been associate emergence of recent graphic style jobs. This evolution has modified the whole landscape of careers during this field. Demand for “traditional” graphic designers WHO work primarily for print publishers has fallen considerably, however that doesn’t tell the complete story. Employment of graphic styleers in pc systems design services is projected to grow by twenty four % through 2028, in line with the Bureau of Labor Statistics (BLS).1 a lot of of this demand is spurred by business’ and organizations’ enlarged would like for digital graphics and representational process as they aim to extend their digital presence.

So thereupon aforementioned, what area unit some common graphic style job titles? we tend to analyzed over thirty,000 job postings line of work for a graphic style degree over the past year.2 the info helped US confirm the foremost common job titles:

·         Graphic designer

·         User expertise (UX) designer

·         Web designer

·         Art director

·         Creative director

As you'll see, once armed with the correct information and coaching, there area unit many graphic style job choices out there. you have got the power to cater your career to your personal skills and interests.

Popular graphic style tools

Now that you just understand what kind of jobs and specializations area unit out there, it’s useful to familiarise yourself with the graphic style tools that facilitate get the duty done. one among the foremost basic, and least valuable, tools designers use may be a volume. Graphic designers can typically sketch out concepts or rough drafts on paper before turning to a pc to finish the method.

That being aforementioned, computers and style software system area unit necessities in today’s digital climate, even though you're planning for print. the sort of pc you would like relies on preference, however once it involves software system, Adobe merchandise like Photoshop, artist and InDesign area unit mainstays within the graphic style world. If you're simply starting and don’t wish to decide to the high tag Adobe merchandise typically carry, similar free ASCII text file software system like lameness will assist you begin to master the fundamentals.

 Lastly, concepts and inspiration area unit what a graphic designer wants most. “You have to be compelled to have a solid construct serving because the foundation of your style and communication,” explains Chad Birenbaum, co-founder of pin style. “This construct and plan has to work on paper initial and so the pc ought to be used as a tool to bring the construct to life.” Graphic designers gain inspiration from the globe around them, therefore if you're distressed you aren’t inventive enough, go outside, bounce concepts off your peers or ask for concepts from the net. There many exalting graphic style blogs which will facilitate get your inventive juices flowing.

[maxverawellness]

What is Nano-Enhanced CBD Oil? How Does It Work?

If you are shopping for CBD oil, you may have heard varieties of terms often used to describe different CBD products. Some of them are formulated to give you instant results, some others offer long-lasting effects, even, some are touted for their enhanced bioavailability. In this article we are going to discuss nano-enhanced CBD. Nano CBD is considered to be the best type of hemp products. It is well-known for its higher absorption rate. So before you place an order for nano CBD, it’s important to know and understand what it is.

What is Nano CBD?

To give you a better idea of what nano CBD is, let’s break it into “nano” and “CBD”. Nano refers to nanotechnology. This technology is conducted at nanoscale. Which means, this technology is used to manipulate compounds at molecular levels. In more detail, scientists can manipulate compounds to about one billionth of a meter. It’s tiny, really tiny. 

CBD, on the other hand, is derived from the hemp plant. It is one of 120+ chemical compounds that the hemp plant contains. These compounds are also known as cannabinoids. Each cannabinoid offers a range of specific therapeutic effects. But, CBD has been found to offer an array of health benefits. 

Nano CBD is a type of cannabidiol that is enhanced by adding an emulsifier carrier in it. It offers higher bioavailability by increasing the absorption of micro CBD particles into the human body cells. CBD has become a popular remedy to common ailments like inflammation, pain, anxiety, heart complications, and insomnia. As it interacts with the receptors all over the body, there’s a convincing reason to believe it can help us in many ways. And so, top CBD oil brands are now creating a range of nano CBD oil products.

How Does Nano CBD Work?

To create Nano CBD, in the first step, molecules of CBD are broken down into nanoscale particles. Then it is coated using micro-carriers that enhance the CBD particle delivery into the body cells. The most common carrier used to create nano CBD is liposome. Liposome is a kind of “fat-pocket” which is made of phospholipids. Generally, nano CBD works in three different ways:

Increasing Bioavailability

Nano particles are very tiny and can easily get absorbed into the bloodstream. The reduced size of the particles makes it easy for them to move through the cell membrane. By increasing the surface area for absorption, nano particles give you faster results. As a result, if you are looking for instant results, you can use nano enhanced CBD oil products. 

Protecting the Core Compounds of CBD

Perhaps, it is one of the most important features of nano CBD. Usually, when you take CBD orally, it has to pass through the gastrointestinal system before reaching the bloodstream. In this phase, the biggest share of what you have ingested is degraded and only a very small amount of CBD makes it into your blood. Indeed, research says, when you take oral CBD, only 4%-6% of this compound reaches your bloodstream. It indicates that the bioavailability is too low. 

But, when CBD is coated using a micro-carrier, it protects CBD from being degraded to a great extent. It preserves all the core compounds of CBD and ensures they are delivered in the anticipated dose. Nano CBD offers the maximum absorption rate. Compared to the normal CBD oil, nano CBD can provide up to 80% bioavailability. 

Targeting Specific Areas

When you take CBD, it works on the endocannabinoid system (ECS) in your body. But, in the case of nano CBD, it’s more specific. Nano enhanced CBD can easily detect the CB1 and CB2 receptors in the ECS. As a result, it can work by targeting the receptors resulting in increased overall efficiency. 

While nano CBD provides a very high level of bioavailability, it may not be similarly effective for everyone. How you will respond to CBD or how effective it will be on your body depends on many things. Your metabolism, biochemistry, and body mass index may influence the way CBD works on you. On the other hand, there’s a variety of doses for each condition. So before taking CBD for a particular condition, you should know which and what type of CBD product is suitable for you.

Is Nano-Enhanced CBD Legal?

In 2018, the World Anti-Doping Agency added CBD in its list of approved substances. This act has initiated a new revolution in the CBD industry. Also, with the passage of the 2018 Farm Bill, cultivation of hemp and trading in hemp derived products became legal across the USA. Therefore, CBD is a legal substance. But the only requirement that the manufacturers and brands should meet is the legal amount of THC. THC is the major psychoactive cannabinoid which creates euphoric effects on users. So, CBD products containing less than 0.3% THC are legal in all 50 states in the USA.

How to Spot High-Quality Nano CBD

Now you know what nano CBD is and what are its benefits. But when you are shopping for nano CBD, you should be able to identify the good quality products. But how should you do it? Here are a few tips that can help you through:

When choosing the right products, make sure the CBD company uses state-of-the-art technology. You can visit their website and get some idea about the technologies they are using. You can also contact their customer support to know what they are using to create and enhance their CBD oil.

Next, look for third-party lab test results. Almost every CBD manufacturer tests its products in their in-house testing facilities. But there is a risk of manipulation. Therefore, reputable CBD companies have their products tested in individual laboratories to ensure the quality, potency, safety, and consistency of their CBD oil is accurate.

Choose products that are free from solvents and contaminants like pesticides, and fertilizers. Many companies use mass-produced hemp plants to create CBD oil. But some growers often use several types of chemicals to enhance growth. When CBD oil is extracted from such hemp plants, those harmful chemicals may end up in the CBD oil.  On the other hand, some manufacturers use solvents like benzene and butane during the extraction process. These chemicals can cause very bad effects if you consume them with your CBD oil. 

Want to Start Your Own CBD Business?

Starting a CBD business is always fascinating. But the truth is, it requires a huge investment to kick off your journey as a CBD brand. But you can also introduce the market with your own line of products with minimum capital. All you have to do is join a whaite label CBD program that many companies are offering. 

There are plenty of manufacturers who are offering white labeling opportunities. But make sure you are sourcing your products from a reputable CBD company. Maxvera Wellness is one of the top-notch manufacturers of white label CBD products and other high-quality nano supplements. Their proprietary nano emulsification process ensures the highest bioavailability in the private label CBD products they manufacture.

 After years of supplying other manufacturers and companies with high-quality CBD products and supplements, Maxvera now opened its door for small and medium-sized businesses. This means now you can get your wholesale CBD products right from the manufacturer, cutting out the middleman and thus save time and money.

The Takeaway

Today, technologies like nanotechnology have brought a breakthrough in the pharmaceutical industry. It has also influenced the CBD industry. Nano CBD oil has gained a remarkable popularity for its ability to provide enhanced bioavailability and therapeutic benefits. After all, to enjoy up to the best using nano CBD, ensure you are buying good-quality products from the best CBD oil brands.

[silly-jellyghoty]

US citizen here who also works at a bank and our currency SUCKS. Like not only do our security measures blow, but we also allow old bills to be recirculated, instead of having us turn them in and destroy them... and then discontinuing their use thereafter. it makes detecting fraud horribly difficult for all involved. also i can confirm that canadian smells like maple syrup. I work at a branch that does international currency and we carry Canadian.

Well, as for old money, there's a nice system here we actualy used a few times already and it WORKS.

1) TOTAL SWITCH OF ALL MONEY, BOTH COINS AND BANKNOTES AS A RESULT OF ENTERING EU

First time I remember that any switch happened was during our transition from Slovenská Koruna to Euro. Transition was happening for 4 years total and it looked like this: for first two years, every single item in shops was labeled with both old and new currency price tags. As they need to be reprinted regularly due to change of price for the product, this wasn't a problem. It gave people time to not only get used to new currency (shape, size and SAFETY SIGNS TO CHECK FOR AUTHENTICITY OF BANKNOTES were highly propagated at time in form of posters and tv spots) but also to new prices as the ratio of SK to EUR was 30.126 : 1.

The second two years was a money switch itself - you payed with SK and got back EUR. After 2 years, there were no more crowns in circulation whatsover. Small banknotes. Thousands. Single 1 crown coins. Nothing.

Of course people kept some as a memento and of course sometimes families find whole rolls of old banknotes laying around in their deceased granpa's attics. But those can be exchanged in banks without a problem. For free. Just because they can't be used to pay for coca cola and potato chips it doesn't mean they have zero value. It's just that they can't circulate anymore.

2) PARTIAL SWITCH OF CURENCY

Since then there have been a few more changes to banknotes in EU. One reason is the safety. Another is that since they are not made of durable plastics but a cotton paper, as time goes they tear. So since they had to be taken from the circulation and replaced by new crispy ones, they could be as well as upgraded as a whole.

Again. No one was throwing stones on anyone for using old banknotes, no. You just payed with them in store as usual. At the end of the day they were send to bank and turned to electronic money on store's account. Banknotes were sorted by value, checked for torn or otherwise damaged pieces and those, together with old version of banknotes, were send to disposal as it have been done every day for as long as modern paper money exists. Then and ONLY then, new ones entered the market. There wasn't any sudden overflow with one or another bill, no.

It happened to 5€ first as it's the most used an thus generaly the most damaged back in 2013 through 2014. I actualy worked retail back then and all we had to do was to mind that we give back new banknotes if possible. If not, then d'uh, tomorrow is also a day and we had whole 2 years of breaking money and returning change ahead of us, so nbd. In the morning we got a bunch of new fives. At the evening we put a slightly bigger bunch of old ones into shop safe. The next morning we picked new ones again and so on. It's realy simple.

Then next year it was time to switch 10€ and a year after 20€. In 2017 it was 50€ switch and new 100€ and 200€ came only this May. There's also a 500€ banknote but as they are used just rarely as people tend to pay such high sums in electronic form, there won't be an upgrade for that one.

And you know what happens with 500s? The very same damn thing that happened to any other banknote. Sooner or later someone uses it. It gets to cash register. It reaches bank. The next day bank sends back new crispy 200s and 100s instead.

That's it. That's the whole proces of switching curency. It can be done sliwly through a decade one banknote by one or it can just HAPPEN within 2 years all at once. That's if government actualy gives a shit about it and funels a bit of those money they spend on funny clothed people doing phew phew every year to actualy fix their home situation a bit.