#implied bickel

[ikilledtvguy]

yaay! fun and games

it’s on my youtube btw….if any of u wanna check that outttt

[lilacs-stash]

Breakup bros comic I've had in my head for MONTHS had to get it out before the new episode drops

[5ome-7ype-0f-5hapeshifter]

id dont fucking knwo what i was thinking whern i was making this

warning. this shit Loud.

original audio is here, BUT i downloaded the audio from here. so. yuh.

please reblog to put nickel inanimate insanity screeching like a damn seagull over balloon's existence on someone's timeline.

[jxcquelynn]

suspiciously nickel ii shaped song:

[gagney]

wow look at trophy go, bein a nice guy

[presssorg]

High-profile Canopy Growth co-CEO Bruce Linton steps down

‘My turn is over’: High-profile Canopy Growth co-CEO Bruce Linton steps down Bruce Linton, the high-profile face of Canada’s marijuana giant Canopy Growth Corporation, announced Wednesday that he is stepping down as co-CEO and board member, effective immediately. “Creating Canopy Growth began with an abandoned chocolate factory and a vision,” Linton said in a statement Wednesday. “The Board decided today, and I agreed, my turn is over.” Canopy, the world’s largest publicly traded cannabis company by market value, said Mark Zekulin will become the sole CEO of the company and will work with the board to begin a search to identify a new leader. Rade Kovacevic, who currently leads the company’s Canadian operations and recreational strategy, will take over the role of president from Zekulin. Canopy Growth’s U.S.-listed shares were down 1.4% premarket. With files from Reuters   Canopy Growth Corporation, formerly Tweed Marijuana Inc., is a cannabis company based in Smiths Falls, Ontario. Tweed was founded by Bruce Linton and Chuck Rifici in 2013, and renamed Canopy Growth Corporation in 2015. Wikipedia Stock price: WEED (TSE) $50.39 -2.10 (-4.00%) Jul. 3, 9:44 a.m. EDT - Disclaimer CEO: Bruce Linton (2014–) Headquarters: Smiths Falls Revenue: 40 million CAD (2017) Subsidiaries: Tokyo Smoke, This Works Products Limited, MORE  

Canopy Growth Announces Leadership Transition 

Logo: Canopy Growth Corporation (CNW Group/Canopy Growth Corporation) Bruce Linton to step down as co-CEO and Canopy Board member Mark Zekulin remains CEO Company Launches Search to Identify Leader to Guide Next Phase of Growth TORONTO and SMITHS FALLS, ON, July 3, 2019 /CNW/ - Today, Canopy Growth Corporation ("Canopy Growth" or the "Company") (TSX: WEED) (NYSE: CGC) and Bruce Linton announced that Bruce will step down as co-CEO and Canopy Board member. Mark Zekulin has agreed to become the sole CEO of the company and will work with the Board to begin a search to identify a new leader to guide the company in its next phase of growth, which will include both internal and external candidates. Rade Kovacevic, a long-serving member of the team currently leading all Canadian operations and recreational strategy will assume the role of President. These changes are effective immediately. "Creating Canopy Growth began with an abandoned chocolate factory and a vision," said Linton. "The Board decided today, and I agreed, my turn is over. Mark has been my partner since this Company began and has played an integral role in Canopy's success. While change is never easy, I have full confidence in the team at Canopy – from Mark and Rade's leadership to the full suite of leadership – as we progress through this transition and into the future." "We thank Bruce and Mark for establishing the foundation for a company that is very well-positioned to lead in the emerging global cannabis market," said Canopy Growth board director, David Klein. "We are also excited to embark upon our next phase of growth as global leader in the cannabis industry." Canopy Growth has experienced rapid growth since being founded in 2013, establishing leading positions in Canada'smedical and recreational cannabis markets and building an emerging presence in a number of additional markets around the world. The company recently received a $5 billion (CAD) investment from Constellation Brands, a leading beverage alcohol company, which provides a significant benefit as Canopy continues to establish a first-mover advantage in the quickly evolving global cannabis market. "While Canopy will never be the same without Bruce, the team and I look forward to continuing to do what we have done for the past 6 years: investing in world class people, infrastructure and brands, and always seeking to lead through credibility and vision," said Zekulin. "I personally remain committed to a successful transition over the coming year as we begin a process to identify new leadership that will drive our collective vision forward. I know the company will continue to thrive as the Canopy story continues on for years to come." The Board has also appointed John Bell as its Board Chair, to be reviewed at the Board's annual meeting in September when new board members are elected. Bell has served on the board as lead director for 5 years. About Canopy Growth CorporationCanopy Growth (TSX:WEED, NYSE:CGC) is a world-leading diversified cannabis, hemp and cannabis device company, offering distinct brands and curated cannabis varieties in dried, oil and Softgel capsule forms, as well as medical devices through Canopy Growth's subsidiary, Storz & Bickel GMbH & Co. KG. From product and process innovation to market execution, Canopy Growth is driven by a passion for leadership and a commitment to building a world-class cannabis company one product, site and country at a time. Canopy Growth has operations in over a dozen countries across five continents. Canopy Growth's medical division, Spectrum Therapeutics is proudly dedicated to educating healthcare practitioners, conducting robust clinical research, and furthering the public's understanding of cannabis, and has devoted millions of dollars toward cutting edge, commercializable research and IP development. Spectrum Therapeutics sells a range of full-spectrum products using its colour-coded classification Spectrum system as well as single cannabinoid Dronabinol under the brand Bionorica Ethics. Canopy Growth operates retail stores across Canada under its award-winning Tweed and Tokyo Smoke banners. Tweed is a globally recognized cannabis brand which has built a large and loyal following by focusing on quality products and meaningful customer relationships. From our historic public listing on the Toronto Stock Exchange and New York Stock Exchange to our continued international expansion, pride in advancing shareholder value through leadership is engrained in all we do at Canopy Growth. Canopy Growth has established partnerships with leading sector names including cannabis icons Snoop Dogg and Seth Rogen, breeding legends DNA Genetics and Green House Seeds, and Fortune 500 alcohol leader Constellation Brands, to name but a few. Canopy Growth owns 12 licensed cannabis production sites with millions of square feet of production capacity, including more than one million square feet of GMP certified production space. For more information visit www.canopygrowth.com Notice Regarding Forward Looking StatementsThis news release contains "forward-looking statements" within the meaning of the United States Private Securities Litigation Reform Act of 1995 and "forward-looking information" within the meaning of applicable Canadian securities legislation. Often, but not always, forward-looking statements and information can be identified by the use of words such as "plans", "expects" or "does not expect", "is expected", "estimates", "intends", "anticipates" or "does not anticipate", or "believes", or variations of such words and phrases or state that certain actions, events or results "may", "could", "would", "might" or "will" be taken, occur or be achieved. Forward-looking statements or information involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Canopy Growth or its subsidiaries to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements or information contained in this news release. Examples of such statements include statements with respect to national and international operations and expansion. Risks, uncertainties and other factors involved with forward-looking information could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied by such forward-looking information, including the Company's executive transitions and departures, and such risks contained in the Company's annual information form dated June 24, 2019 and filed with Canadian securities regulators available on the Company's issuer profile on SEDAR at www.sedar.com. Although the Company believes that the assumptions and factors used in preparing the forward-looking information or forward-looking statements in this news release are reasonable, undue reliance should not be placed on such information and no assurance can be given that such events will occur in the disclosed time frames or at all. The forward-looking information and forward-looking statements included in this news release are made as of the date of this news release and the Company does not undertake an obligation to publicly update such forward-looking information or forward-looking information to reflect new information, subsequent events or otherwise unless required by applicable securities laws. SOURCE Canopy Growth Corporation Published at Wed, 03 Jul 2019 11:29:19 +0000 Read the full article

[knowledge-world]

The exponential growth of Crypto Currency

With regards to the destiny of cash, there may be a growing accord that virtual currencies are set to count on a noteworthy part. One cryptographic money, especially, has entered widespread society vocabulary because the cross-to superior useful resource: Bitcoin.

Today that progressions because of the work of Abeer ElBahrawy at City College in London and a couple pals who have inspected the cryptographic cash showcase all in all and say that it is essentially greater puzzling and develop than many had notion. The development of this market even bears an astounding likeness to the improvement of organic groups in severa distinctive tiers, giving a few information into the way the cryptographic money market may trade later on.

To start with a few foundation. The large check with superior coins is to prevent unapproved duplicating. Digital types of cash make use of  additives to preserve this. The first is to distribute every exchange in an open document and to save numerous duplicates of this file on-line in a manner that allows all of them to be therefore looked at and refreshed. This averts twofold spending—using the equal bitcoin to purchase  awesome things.

The second system is to make certain the file cryptographically. Each refresh gathers together a scope of new exchanges and adds them to the present day report. Be that as it is able to, to try this, the previous model of the report is first solidified and scrambled.

The new shape of the record—referred to as a rectangular—incorporates the encoded replica of the earlier than document. Anyone can make use of this encoded facts to create a range of that can be applied to test the veracity of the piece. In any case, it's far significantly tough to produce this variety computationally seeking to enjoyment the framework. It is that this thing—that the portions are something but tough to test but amazingly difficult to copy—that secures the framework.

Obviously, because the report maintains on being refreshed, new portions ought to be made, piggybacking at the vintage ones and making an unbroken chain of squares. Consequently, the time period blockchain innovation.

Bitcoin is through a protracted shot the maximum famous of these digital styles of money. It is moreover most of the most set up, having first developed in 2009. In any case, it's far in no manner, form or shape the primary virtual foreign money. So an exciting inquiry is the way by means of which the digital cash market is growing.

To discover, ElBahrawy and co tested the behavior of 1,500 cryptographic kinds of cash that have risen due to the fact 2013 and say that someplace inside the variety of 600 of them are efficiently exchanged nowadays. They say this market has as of late entered a time of exponential improvement and is presently well worth $54 billion. (By exam, the combination sum of cash on the planet is about $60 trillion.)

Yet, even as this virtual currency marketplace is growing speedy, ElBahrawy and co show that precise elements of it are consistent. For instance, the quantity of dynamic virtual currencies has stayed approximately the same on the grounds that 2013 as has the piece of the overall industry appropriation, which takes after a high-quality energy regulation.

The institution likewise indicates how this dispersion may be duplicated making use of a fashionable model of development in which they hook up with figures for the price at which economic forms increase and wither away.

This energy regulation conveyance takes place in an in depth type of frameworks. For example, a comparable law depicts the span of religions, of dialects and even of wars (via variety of passings). In none of these frameworks is there are any desired faith or dialect or warfare. Be that as it could, in light of gift instances, they all body this sort of dissemination.

The way that length dissemination of cryptographic kinds of cash takes after a comparable regulation is large. It infers that to the volume the marketplace is concerned, all monetary bureaucracy are essentially the same. "The healthy with the statistics demonstrates that there's no distinguishable population degree settlement on what is the "great" cash or that distinctive monetary requirements are favorable for numerous makes use of," say ElBahrawy and co.

Regardless of whether or not this is real is a long way from being manifestly true. Different pundits have called attention to diverse specialized restrictions associated with Bitcoin, and this has enlivened any other era of virtual currencies, as an example, Ethereum. Regardless of whether this may effect the market remains to be seen.

While this exponential improvement is non-stop, Bitcoin's piece of the general industry is falling. The main five greatest monetary requirements—Ethereum, Swell, Litecoin, Dash, and Monero—now represent 20 percentage of the market. What's more, the pattern for Bitcoin is clear. "This could foresee Bitcoin piece of the pie to vary round 50 percentage by means of 2025," say the organization.

Another calculate the market is that cryptographic forms of cash aren't applied just as cash. Bitcoin is additionally commonly applied for idea and might likewise be applied for nonmonetary uses, as an instance, timestamping.

For huge quantities of these programs there may be an unmistakable benefit to having a solitary coins that everybody concedes to. "While the usage of cryptographic varieties of cash as theoretical sources ought to increase broadening, their appropriation as installment approach (i.E., the traditional usage of a mutual medium of installment) have to increase a victor take-all administration," say Bickell and co.

Be that as it could, involvement with distinct organic structures endorse that is in no way, form or form certain to take place. For example, a solitary PC working framework has never possessed the capability to outcompete all others, paying little recognize to the savagery of its corporation. Neither has any human dialect or faith or mildew worn out all others.

This shouldn't imply that it can't arise. However, except there's noteworthy outdoor manipulate of this market, the probability is that there may be vital variations inside the cryptographic cash exhibit for years to come.

[team--b]

MODEL UNIT

Project Type: Objects Location: Louisville Status: Installation

A full-scale representation of a young professional urban loft apartment in a gentrifying neighborhood. While a minimalist and modern aesthetic is fashionable, the amount of consumer goods targeted toward this aesthetic and readily found in its idealized apartment feels counter to such a philosophy. This aesthetic is perpetuated by social medias like Pinterest and Instagram and is then used by developers to renovate with the cheapest possible materials while applying a superficial, trendy appearance to turn the highest profit. Marketing imagery and ‘model units’ are staged and filled with stock entourage to imply a certain lifestyle, and thus, a desired tenant. In this way, architects as visualizers of un-built work are complicit with gentrification - projecting imagery that appeals to specific socio-cultural consumers.

Model Unit was exhibited at HOUSEGUEST Gallery this spring. HOUSEGUEST is an independent artist-run project space located in Louisville, Kentucky. The space was founded in January of 2017 by artist Megan Bickel and her husband, chef, Jacob Wilson. It's location is within the living room of the couple.

[componentplanet]

Astronomers Find ‘Impossible’ Planet Circling Tiny Star

(Image credit: Guillem Anglada-Escude—IEEC/Science-wave, using SpaceEngine.org (CC BY 4.0))

One of the ongoing puzzles in astronomy is that very few solar systems that we’ve examined to date look anything like ours. It’s common, for example, for solar systems to have so-called Hot Jupiters, planets the size of Jupiter that circle their host stars at a closer distance than Mercury circles our own Sun. Many solar systems have planets that fall in-between the size of Earth and Neptune, while we have no such worlds. In other solar systems, Super-Earths — rocky planets — are often found much closer to the Sun, while our largest and farthest planets are all gas giants.

These differences imply that our own theories of planetary formation and evolution may need tweaking to account for how our solar system appears to be odd, for lack of a better way of putting it. As if to reinforce that argument, astronomers have found a planet that appears to be much too large for the star it’s orbiting. Their work, published in Science, raises questions about how a system like this could form in the first place.

GJ 3512 b is a gas giant orbiting a tiny red dwarf, GJ 3512. The planet itself is in an eccentric, 204-day orbit around its star, but spends most of its time closer to its parent than Mercury is to Sol. GJ 3512, however, can only manage ~0.2 percent of our Sun’s solar output. But a planet the size of GJ 3512 b isn’t supposed to exist.

“The discovery was surprising because theoretical formation models suggest that low-mass stars typically host small planets, similar to Earth or small Neptunes,” said astrophysicist Juan Carlos Morales of the Institute of Space Studies of Catalonia, who led the research. “In this case, we have found a gas giant planet similar to Jupiter around a very small star,” Morales said.

To put this in perspective, GJ 3512 is only about 250 times the mass of GJ 3512 b, whereas the Sun is more than 1,000 times the mass of Jupiter.

Credit: C. Bickel/Science

According to their measurements, GJ 3512 is only about 35 percent larger than Jupiter, while the planet, GJ 3512 b, is at least 46 percent the size of Jupiter. Thus, we have a Jupiter-sized planet circling a very small star, where Jupiter-sized planets are not expected to form. Furthermore, GJ 3512 b isn’t the only planet orbiting GJ 3512; there’s a GJ 3512 c signal in the data as well. The standard model of planetary formation, in which pebbles accrete together until a core of at least 5-15 Earth masses exists followed by a relatively quick growth to gas giant size, does not fit the known circumstances in this case.

In order to form a gas giant, there has to be enough gas in a protoplanetary disk in the first place. As a solar system forms, the amount of gas within it is continually reduced by the wind of the nascent star and by other planetesimals and planets, which pull material into their own orbits. Around red dwarfs, the accretion process is typically too slow for gas giants to form this way before gas is lost to surrounding space. Giant planets only have a limited window to form around their host stars, typically estimated at 3-10 million years.

There is, however, an alternate theory of planetary formation known as gravitational disk instability. According to this theory, clumps of dust and gas may have differential temperatures, with cold areas becoming denser over time until the gas cloud collapses into a planet. Unlike theories of core or pebble accretion, this process could theoretically occur extremely rapidly, within a matter of some thousands of years as opposed to over millions of years.

Up until now, core accretion has been the favored explanation for how planets form, but GJ 3512 b is enough of an oddball that scientists don’t think our standard models can explain it. It may be an example of a planet that formed via gravitational disk instability, evidence that our existing models don’t account for all necessary variables in the process, or both. Either way, we now know there’s at least one other oddball solar system out there — even if it’s still completely different than our own.

Top image credit: Guillem Anglada-Escude—IEEC/Science-wave, using SpaceEngine.org (CC BY 4.0))

Now Read:

NASA Produces Stunning Simulation of a Black Hole

NASA Says Venus May Have Supported Life Billions of Years Ago

NASA Hires Lockheed Martin to Build up to 12 Orion Spacecraft

from ExtremeTechExtremeTech https://www.extremetech.com/extreme/299218-astronomers-find-impossible-planet-circling-tiny-star from Blogger http://componentplanet.blogspot.com/2019/09/astronomers-find-impossible-planet.html

[chestnutpost]

Spectrum Therapeutics Provides Update on Its Global Clinical Research Program and Unveils Pharmacovigilance

SMITHS FALLS, Ontario, June 6, 2019 /PRNewswire/ — Spectrum Therapeutics (“Spectrum”), the medical division of Canopy Growth Corporation (TSX: WEED) (NYSE: CGC) (the “Company” or “Canopy Growth”) is pleased to share an update on its efforts to develop and commercialize validated cannabis medicines through clinical trials. Demand for cannabinoid-based medicines is emerging around the world. With a highly experienced scientific team and the resources needed to conduct robust clinical trials, Spectrum Therapeutics is pursuing research to introduce products for the therapeutic areas of pain, mood and sleep and to gain access to new markets independent of medical cannabis laws.

CLINICAL RESEARCH

Spectrum Therapeutics is focused over the next 24 months to further the science of cannabinoids and provide evidence by way of clinical trials on what conditions medical cannabis can treat. This research includes product design and ingredient selection, formulation, and safety and efficacy testing towards the development of standardized cannabis drug formulations and dose delivery systems. Research activity is occurring in two main areas: registration trials and exploratory studies. 

Registration trials begin with phase I studies of cannabinoid products covering a spectrum of proprietary THC and CBD ratios. These initial trials provide critical dosing and safety data to inform subsequent phase II trials. Spectrum Therapeutics is pleased to announce that two phase I trials have already been completed, one each in Canada and Chile.

Exploratory “proof of concept” studies use a range of Spectrum products and design methodologies to explore different dose responses, and safety and efficacy signals for target conditions. Those that show promising results will be added to the registration trial pipeline and their initial findings will allow for optimal phase II trial design. The first proof of concept phase IIb “in human” clinical trial previously announced by the Company, to evaluate the use of medical cannabis for treating insomnia, is in progress in partnership with Drs. Julie Carrier and Alex Desautels at the Université de Montréal. It is expected to be completed by calendar Q2 2020 with results announced by calendar Q3 2020.

Other proof of concept studies are currently underway in partnership with researchers including Dr. Bernard Le Foll at the Centre for Addiction and Mental Health, Dr. Mary-Ann Fitzcharles at McGill University, and Dr. Angela Genge at the Montreal Neurological Institute. Over twenty conditions are being examined across these studies, including pain, sleep, and mood/anxiety disorders. Spectrum Therapeutics is also exploring areas such as neurodegenerative disorders in addition to the previously announced research partnership with NEEKA Health Canada and the NHL Alumni Association which is examining the efficacy of CBD-based therapies as part of a treatment for concussion symptoms. This clinical trial is expected to register its first patients by October 2019 with preliminary results by July 2020.

Recently acquired C3 Cannabinoid Compound Company (“C3“) is currently progressing a clinical trial for the use of dronabinol to treat spasticity due to multiple sclerosis. Additionally, research on the potential of medical cannabis to treat cancer-related pain is also in the works with Beckley Canopy Therapeutics, a partnership established between U.K. drug research institute, The Beckley Foundation and Canopy Growth. Patient registrations for this trial are expected in September 2019.

To support its research program, Spectrum Therapeutics is pleased to announce the appointment of Dr. Marcel Bonn-Miller as Global Clinical Scientific Director. He brings to the team 18 years of experience researching cannabinoids and their various effects, has received funding for 27 research grants, and has led or contributed to 19 clinical trials. His work has been featured in 139 academic publications and 161 conference presentations, and he also serves on the editorial boards of five academic journals. Dr. Bonn-Miller previously worked as Director of Cannabinoid Research for Zynerba Pharmaceuticals, a leading transdermal cannabinoid pharmaceutical company. He is also an adjunct Assistant Professor at the University of Pennsylvania Perelman School of Medicine, known for his work examining the potential of cannabis in treating post-traumatic stress disorder.

Dr. Bonn-Miller will be supported by Hunter Land and Drs. Ryan Lanier and Erica Peters as Associate Directors. Land was instrumental in bringing the first cannabis-derived CBD medicine developed for patients with treatment-resistant forms of epilepsy, including Dravet and Lennox-Gastaut syndromes, to FDA approval. Dr. Peters was the lead clinical cannabis scientist for four years at Battelle, the world’s largest non-profit research and development organization, and Dr. Lanier worked for Analgesic Solutions where he consulted on the development of pain medications for FDA approval.

PHARMACOVIGILANCE

In the interest of patient safety and good clinical practice, Spectrum Therapeutics is pleased to announce the implementation of a unique global pharmacovigilance program to capture and document adverse events reported from the worldwide use of its medical cannabis products in addition to the Company’s Canadian recreational cannabis brands including Tweed and DNA Genetics, and its CBD product offerings. 

Pharmacovigilance, also known as drug safety, is defined as the science and activities relating to the detection, assessment, understanding and prevention of adverse effects from the use of pharmaceutical products. While Spectrum Therapeutics and Canopy Growth were already reporting any adverse reactions to its cannabis products as per Health Canada regulations, the launch of this global pharmacovigilance program ensures that all employees are trained on how to identify and report adverse events. The Company’s internal Pharmacovigilance team is responsible for analyzing and entering events into a global safety database compliant with regional regulatory requirements.

A global independent safety monitoring board chaired by Professor Yola Moride at the Université de Montréal will periodically review adverse event summaries and advise the Spectrum Therapeutics scientific team regarding product safety and clinical trial design.

“We believe that this strategic approach to global clinical research, in collaboration with outstanding investigators and institutions, and supported by our first-rate team of scientists, will generate innovative products for a number of indications with significant unmet needs,” commented Dr. Mark Ware, Chief Medical Officer, Canopy Growth. “We are also pleased to announce the launch of our global pharmacovigilance program whereby every one of our 3000+ staff worldwide are trained in reporting adverse events. It’s an important step towards establishing drug safety and will advance our efforts to provide patients with accepted, clinically validated cannabis medicines while transparently demonstrating the relative risks of cannabis.”

Here’s to (Clinically Validated) Future Growth.

About Canopy Growth Corporation

Canopy Growth (TSX: WEED,NYSE: CGC) is a world-leading diversified cannabis, hemp and cannabis device company, offering distinct brands and curated cannabis varieties in dried, oil and Softgel capsule forms, as well as medical devices through the Company’s subsidiary, Storz & Bickel GMbH & Co. KG. From product and process innovation to market execution, Canopy Growth is driven by a passion for leadership and a commitment to building a world-class cannabis company one product, site and country at a time. The Company has operations in over a dozen countries across five continents.

The Company’s medical division, Spectrum Therapeutics is proudly dedicated to educating healthcare practitioners, conducting robust clinical research, and furthering the public’s understanding of cannabis, and has devoted millions of dollars toward cutting edge, commercializable research and IP development.

From our historic public listing on the Toronto Stock Exchange and New York Stock Exchange to our continued international expansion, pride in advancing shareholder value through leadership is engrained in all we do at Canopy Growth. Canopy Growth has established partnerships with leading sector names including cannabis icons Snoop Dogg and Seth Rogen, breeding legends DNA Genetics and Green House Seeds, and Fortune 500 alcohol leader Constellation Brands, to name but a few. Canopy Growth operates ten licensed cannabis production sites with over 4.4 million square feet of production capacity, including over one million square feet of GMP certified production space. For more information visit www.canopygrowth.com

Notice Regarding Forward Looking Statements

This news release contains “forward-looking statements” within the meaning of the United States Private Securities Litigation Reform Act of 1995 and “forward-looking information” within the meaning of applicable Canadian securities legislation. Often, but not always, forward-looking statements and information can be identified by the use of words such as “plans”, “expects” or “does not expect”, “is expected”, “estimates”, “intends”, “anticipates” or “does not anticipate”, or “believes”, or variations of such words and phrases or state that certain actions, events or results “may”, “could”, “would”, “might” or “will” be taken, occur or be achieved. Forward-looking statements or information involve known and unknown risks, uncertainties and other factors which may cause the actual results, performance or achievements of Canopy Growth or its subsidiaries to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements or information contained in this news release. Examples of such statements include “expected to be completed by Q2 2020 with results announced by Q3 2020”, and “those that show promising results will be added to the registration trial pipeline”. Risks, uncertainties and other factors involved with forward-looking information could cause actual events, results, performance, prospects and opportunities to differ materially from those expressed or implied by such forward-looking information, including clinical trial results, product supply, and such risks contained in the Company’s annual information form dated June 27, 2018 and filed with Canadian securities regulators available on the Company’s issuer profile on SEDAR at www.sedar.com. Although the Company believes that the assumptions and factors used in preparing the forward-looking information or forward-looking statements in this news release are reasonable, undue reliance should not be placed on such information and no assurance can be given that such events will occur in the disclosed time frames or at all. The forward-looking information and forward-looking statements included in this news release are made as of the date of this news release and the Company does not undertake an obligation to publicly update such forward-looking information or forward-looking information to reflect new information, subsequent events or otherwise unless required by applicable securities laws.

Contact:

Caitlin O’Hara Media RelationsCaitlin.ohara@canopygrowth.com +1-613-291-3239

Tyler Burns Investor RelationsTyler.burns@canopygrowth.com +1-855-558-9333 ex 122

SOURCE Spectrum Therapeutics

The post Spectrum Therapeutics Provides Update on Its Global Clinical Research Program and Unveils Pharmacovigilance appeared first on The Chestnut Post.

from The Chestnut Post https://www.thechestnutpost.com/news/spectrum-therapeutics-provides-update-on-its-global-clinical-research-program-and-unveils-pharmacovigilance/

[lilacs-stash]

(This is post show as always & a tiny bit ooc for comedy sake)

[bemyeastandwest-blog]

Volcano Vaporizer Review

The Volcano Vaporizer is the king of the tabletop vaporizers, there is no question about it, and it is not anything that we just say, but all end users of vaporizers agree with this assertion. It is ideal for vaporizing each dried herbs and oils and concentrates. It has a large cost and is not transportable, but for individuals who like to vaporize in the ease and comfort of their residence, it is unquestionably the best alternative. It is created by the Storz and Bickel manufacturer. Its development good quality is quite higher, the steam it creates is ideal, the two for its flavor, its density and its temperature and it is also 1 of the easiest vaporizers to use. We have been making use of it ours for more than two many years and it nevertheless operates like the initial day.

If you want to know more about Volcano Vaporizer overview, do not skip this submit In this in-depth Volcano vaporizer overview , we will see its principal qualities, the diverse variations in which it is discovered in the industry and the variations amongst them.

● Size and Weight: Its proportions are: twenty. x 18. cm and it weighs: one.6 Kg. ● Design: Made of stainless steel with a volcano design and style that can make reference to its title. ● Quality: Steam of very substantial good quality. ● Temperatures: a hundred thirty ° C and 230 ° C (266 ° F and 446 ° F) divided into 9 ranges. ● Colors: Stainless Metal Colour ● Warranty: 3 years Different versions offered The Volcano table vaporizer has four attainable configurations to decide on from, based on our tastes, the use we are heading to give it and the funds we want to commit.

With regard to the base we can decide on two distinct configurations:

● Volcano Vaporizer Classic ● Volcano Vaporizer Digital The digital variation of the Volcano tabletop vaporizer incorporates a digital exhibit and buttons to decide on the temperature of the preferred stove. It also incorporates an automatic shutdown technique right after 30 minutes of inactivity, which is very helpful and aids us to increase the lifestyle of our marijuana vaporizer. The major drawback of the digital edition in contrast to the traditional variation is the value more than € one hundred.

The classic edition of the Volcano vaporizer , the most frequent among users, incorporates an analog wheel to control the temperature of the stove, which permits us to change it from position 1 (lowest temperature) to place nine (optimum temperature). the temperature depends on the tastes of every consumer and on the freshness of the herbs found inside the stove. With respect to the relationship valve of the bag with the foundation we can select amongst: ● Solid Valve ● Easy Valve The Strong Valve model of the Volcano vaporizer is created of large top quality stainless metal and warmth resistant plastic. This variation delivers distinct sizes of baggage that are reusable, which saves cash in a year, but with the drawback that the luggage, being reusable, have to be cleaned. In addition, the good quality of the stove and the nozzle are better than in the Simple Valve version .

The Easy Valve model of the Volcano vaporizer is created so that you do not have to invest a whole lot of time on routine maintenance, in return it has a few of disadvantages that we will see below: We only have one bag measurement, which is a little bit rigid considering that Often we will like to share steam with pals and other folks for ourselves. The 2nd drawback is that because of to the fact that you have disposable luggage, you are likely to assume that we have to spend € 25 - € fifty a yr on baggage, always relying on how we use it. We prefer the Sound Valve model because it presents us the flexibility to adapt the size of the bag to our needs, but this selection is dependent on the taste of every one particular, there is no correct selection and a improper one.

As we described just before, the high quality of the steam produced by the Volcano Vaporizer is unequalled , we get a delicate, dense and very flavorful vapor. In get to receive the best results in every single steaming session, we have to grind the quite fine herbs and compact them in the small chamber that has to residence them. The Volcano heats the herbs by convection, which implies that it passes the air at the selected temperature by way of the herbs, hence obtaining a really successful and homogeneous use. The get in touch with surface amongst the very hot air and the herbs is very big, much far more than in all the Vaporizeres of the competitiveness, this plays a fundamental role in the high quality of the steam developed. To go sizzling air by means of the cavity where the herbs are, the Volcano has a ceramic resistance, lined with iron to which fresh air is pushed by a strong pump found in the lower parter of the vaporizer. With the Volcano we can not only vaporize dried herbs but it is also best for evaporating oils and extracts or concentrates.

Detailed info here

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Ep16 prediction

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Nickel ref/hc post 3.0

Yeah it's just minor design updates on the main ref BUT I want all my design/hc stuff for him to be on one post, this is gonna be a longer one.

Also I've decided to add last names to refs now. Nickel's full name is Nicholas Popper. It used to be coin but he changed it later on because of the attachment to his bio family.

He's Knife and Silver's adopted brother, and the middle child.

All season ref. His tail is retractable

In between S2 & S3 design. Depression era. He's roommates with Balloon and sooooo mad about it.

Trinket timeline.

He's partners with Balloon, dating Suitcase, qpps with Box, and causally dating Lightbulb Paintbrush Fan and Trophy. Baseball is his ex. He only has trinkets from people he's in a serious relationship with.

And finally his teen design. He's about 13 here.

And that's it that's my long ref/hc sheet. I like Nickel inanimate insanity the normal amount.

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Baseball

And finally done with the main grand slams (well. Not done done. I need to redo Suitcase's design and I might redraw Balloon's ref). Shouldn't have taken so long considering I'm a grand slams main but eh.

Also working on a ref for his S1 and 2 designs! (As this is post S3)

Lil ship HC cuz I'm testing out adding them to these: He's married to Suitcase and Clover, and Nickel is his ex technically but they are trying to rekindle.

Requesting rules

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Very messy Nickloon stuff I don't feel like making look nice