#i ended up with early stage fatty liver disease
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Very worth noting that keto-like diet can also be very good for type 2 diabetics
this just in: eating like shit for no reason is bad for you
#everyone else keep away from it though#my mum is on it for her diabetes and so for a while i was kinda on it too cause it made shopping easier#i ended up with early stage fatty liver disease
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Fatty Liver Specialist in Chennai
Managing liver health, particularly in cases of fatty liver disease, requires specialized care. This guide provides an overview of the importance of selecting a trusted liver specialist in Chennai and highlights some of the leading experts in the field to help you make an informed decision.
Why Consult a Fatty Liver Specialist in Chennai?
Fatty liver disease is increasingly common, linked to conditions like obesity, diabetes, and high cholesterol. A skilled specialist can offer targeted care and effective management strategies to safeguard liver health and prevent complications.
Understanding Fatty Liver Disease
Fatty liver disease, also known as hepatic steatosis, occurs when fat accumulates in the liver. If untreated, it can progress to more severe conditions, such as liver fibrosis or cirrhosis. Recognizing symptoms early and seeking expert care can make a significant difference in outcomes.
Importance of Early Diagnosis
Detecting fatty liver disease in its early stages allows for timely interventions that can halt or even reverse its progression. Here’s why consulting a specialist early is vital:
Prevention of Progression: Early detection reduces the risk of complications like liver cirrhosis.
Customized Treatment Plans: Specialists provide tailored strategies, including lifestyle changes and medical interventions.
Ongoing Monitoring: Regular follow-ups help track progress and adjust treatments as needed.
Leading Fatty Liver Specialists in Chennai
1. Dr. Aswin Krishna
Qualifications: MBBS, MD, DM (Hepatology)
Experience: 6+ years
Hospital: Apollo Hospital
Specialization: Expert in managing both alcoholic and non-alcoholic fatty liver disease with personalized treatment plans.
Services:
Liver function tests
Fatty liver disease diagnosis and management
Comprehensive care for liver-related complications
2. Dr. I. Shubha Vivekan
Qualifications: MD, DM
Experience: 13+ years
Hospital: VS Hospitals
Specialization: Focused on non-alcoholic steatohepatitis (NASH) and preventive care.
Services:
Early detection and treatment of fatty liver disease
Lifestyle counseling and nutritional guidance
Cirrhosis management
3. Prof. Dr. Mohammed Ali
Qualifications: MD, DM, FCIP, HoD
Experience: 27+ years
Hospital: VS Hospitals
Specialization: Advanced care, including liver transplantation.
Services:
Liver transplant evaluation and treatment
Management of advanced fatty liver disease
Treatment for liver cirrhosis and failure
4. Dr. Radhika Venugopal
Qualifications: MBBS, MD, DM (Hepatology)
Experience: 24+ years
Hospital: CTS Hospitals
Specialization: Pediatric and adult hepatology with a focus on education and prevention.
Services:
Diagnosis and management of fatty liver disease
Preventive liver care
Liver health education
5. Prof. Mohamed Rela
Qualifications: MS, FRCS, DSc
Experience: 28+ years
Hospital: Rela MS Hospital
Specialization: World-renowned for liver transplants and managing end-stage fatty liver disease.
Services:
State-of-the-art liver transplantation
Advanced fatty liver disease care
Comprehensive hepatology services
Diagnostic Tools for Fatty Liver Disease
A combination of tests ensures accurate diagnosis:
Medical History & Physical Exam: Reviews lifestyle, symptoms, and physical signs.
Blood Tests: Includes liver function tests and lipid profiles.
Imaging Tests: Ultrasound and FibroScan to detect fat accumulation and measure liver stiffness.
Liver Biopsy: A definitive method for determining disease severity.
Conclusion
Choosing the right fatty liver specialist in Chennai is key to effective management and better long-term liver health. With early diagnosis, tailored care, and regular monitoring, you can take proactive steps to maintain a healthy liver. For more details : https://draswinkrishna.com/life-after-liver-transplant
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MASLD & Fibroscan (Liver Elastography) Demystified!!
Fatty Liver is no longer an unheard term. The prevalence of fatty liver in India is approximately 30% and that means that nearly one in three person suffers from it. The disease is not as benign as the name and prevalence suggest. This disease is the most common liver disease worldwide. It is on path to become the number 1 reason for liver cirrhosis, liver cancer and liver transplant.
New Terminology
The disease has gone significant change in terminology and is now known as MASLD – Metabolic-Dysfunction Associated Steatotic Liver Disease and recently in 2023 the experts of the world met and proposed the following terminology for types of SLD (Steatotic Liver Disease) or Fatty Liver Disease
MASLD – Previously NAFLD or Fatty Liver
MASH – Previously NASH
MetALD – No previous terminology (Patients also take alcohol in addition).
Risk Factors
MASLD and MASH is usually seen in patients who are obese, overweight and suffer from diabetes, hypertension, sedentary lifestyle, thyroid disease and is habituated to eating processed foods and high-fat high carbohydrate diet.
Progression
MASLD can progress over years to end stage liver disease and leads to complications similar to alcohol associated liver disease. It leads to cirrhosis and then ascites, pedal oedema, bleeding, jaundice, encephalopathy, liver cancer and may warrant liver transplant. In early stage when the disease is reversible, it has no symptoms and hence often ignored. When symptoms do develop, it is usually too late to reverse.
Diagnosis
The diagnosis of fatty liver is based on a sonography or abdominal ultrasound where radiologist will let you know if you have fatty liver. Although, blood tests like liver function tests, lipid profile, HBA1c, CBC and others are often recommended to find out predisposing conditions and complications, it fails to give exact nature of underlying severity or stage of liver disease. For this, non-invasive tests are recommended. These tests are very important to understand the prognosis and treatment prescription. Following image is an idea about some of these tests.
There is a lot of confusion currently in terminology of Fibroscan, Elastography and ARFI. I have created following flow chart to understand this difference.
Fibroscan
It is Transient Elastography. It is the name of the machine which carries out the test of Transient Elastography. Unfortunately, since this is the first elastography technique and is accepted worldwide, the name is used synonymously for the technique. It is similar to XEROX and photocopy where XEROX is the name of the machine and the function is photo company. Fibroscan is produced by a French company called Echosens. This is the only approved and accepted modality worldwide.
The currently available machines of Fibroscan (430,430 Mini, 502, 530, 630) provide following details
CAP – Controlled Attenuation Parameter – It tells the patient about the amount of fat in the liver. The ultrasound when gives Fatty liver Grade1,2 or 3, it is a subjective finding while CAP is an objective number which can be used to monitor treatment and risk stratification. A value above 230 is considered significant
LSM – Liver Stiffness Measurement– It tells you how stiff the liver has become. Stiffer the liver worse is the outcome. The vibration wave generated by the probe travels through the liver and the velocities then picked up to give a definite number. Usually, the number is less than 8 kPa. When the value crosses 14 kPa or above, the chances that the liver has irreversible damage are high. The risk of complications also increases when the value crosses 20 or above.
SSM – Splenic Stiffness Measurement – It is measured over the spleen and it gives risk of developing bleeding from the foodpipe and stomach secondary to liver cirrhosis. These values still require validation and widespread acceptance
The 402 version of the machine is outdated and no longer accepted. The machine has SMART EXAM to improve the efficiency, interoperability and accuracy.
Fibrotouch
Similar to Fibroscan, this machine is made in Asia and available also in India. It works exactly on the same principle as Fibroscan. Instead of CAP, the machine gives UAP. Although used frequently, a lot of Indian doctors, hepatologists and Gastroenterologists have raised questions about its accuracy.
pSWE – Point Shear Wave Elastography
This is type of Elastography which radiologists carry out with the use of their sonography machine. The technique used is different from Fibroscan. Instead of Vibration, the machine uses Acoustic waves and the technique is known as ARFI. The machine provides an advantage of being able to do an ultrasound and elastography with the same machine but it cannot give CAP value and it requires validation to be used as a Fibroscan alternative as of now.
MR Elastography
It is considered one of the best techniques. Availability although is a problem. Only few centres in India provide this facility. It is expensive.
Treatment
The treatment of MASLD is lifestyle modification. If there is fibrosis on the above tests, your doctor might prescribe you medicines to protect the liver in addition. The control of predisposing factors is of paramount importance.
If you suffer from Fatty Liver – MASLD, please contact your Liver Specialist or Hepatologist
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Intussusception is the most common cause of intestinal obstruction in children between 3 months and 6 years of age.
Symptoms of amebic dysentery (or colitis) to some extent may mimic symptoms of ulcerative colitis or Crohn's disease. Usually, the illness lasts about 2 weeks, but it can recur without treatment. The general symptoms include abdominal cramps, diarrhea, passage of 3 to 8 semi-formed stools per day, passage of soft stools with mucus and occasional blood, fatigue, excessive flatulence, rectal pain during bowel movement (tenesmus), and unintentional weight loss. Severe symptoms include abdominal tenderness, bloody stools, and passage of liquid stools with streaks of blood, passage of 10 to 20 stools per day, fever, and vomiting. Amebic colitis is the result of invasive infection of the colonic mucosa by Entamoeba histolytica (E. histolytica).
Zollinger-Ellison Syndrome (ZES) presents with marked gastric acid secretion, ulcer disease of the upper GI tract including the stomach and duodenum, and non-beta islet cell tumors of the pancreas, but it does not normally affect the Islets of Langerhans. Zollinger-Ellison is commonly associated with tumors of delta cells of the pancreas. However, the tumors are also commonly located in other areas such as the duodenum and abdominal lymph nodes. Note that hyper-acidity in the duodenum inactivates pancreatic enzymes and results in diarrhea. Differential diagnosis of ZES includes gastroesophageal reflux disease, MEN1 (Wermer syndrome), peptic ulcer disease, helicobacter pylori infection, gastric outlet obstruction, pernicious anemia, achlorhydria, and pancreatic cancer. Note that hyalinization of the Islets of Langerhans is associated with Diabetes mellitus.
I didn't know that MEN1 is also called "Wermer syndrome." Now I know.
Hepatoblastoma is the most common malignant primary liver tumor in children. I only got that right because I remember Dr. Plummer saying that blast tumors are associated with kids.
Most esophageal varices are located in the lower third of the esophagus.
Apparently, phytate exerts the most profound inhibitory effects on the absorption of zinc (Zn) from the lumen of the small intestine. Never heard of phytate. When I googled it, this is what came up:
Phytate, or phytic acid, is a naturally occurring compound found in all plant foods like beans, grains, nuts, and seeds. In the past, there were concerns that foods high in phytates might reduce the absorption of minerals.
Zinc deficiency has been found in some populations that consume large quantities of unrefined foods. The phytate in these foods may decrease zinc absorption. Note that picolinic acid is the body's prime natural chelator. It is the most efficient chelator for minerals such as chromium, zinc, manganese, copper, iron, and perhaps molybdenum. Zinc picolinate is actually readily absorbable.
Never heard of picolinic acid either.
The most common bacteria linked to ascending cholangitis are gram-negative enteric bacteria, in particular Escherichia coli, followed by Klebsiella and Enterobacter. Treatment consists of antibacterial therapy and removal of gallstones. Note that the presence of antibodies against hepatitis B surface antigen will rule out a hepatitis B infection, and interferon-alfa or ribavirin administration is mostly indicated for hepatitis C treatment.
Unresolved PUD can cause perforations. Perforated ulcers are the most commonly encountered dreaded consequence. Note that common symptoms of perforation include: (1) sudden development of sharp abdominal pain; (2) rigidity and tenderness of the abdomen; (3) symptoms of shock (fainting, hypotension, excessive sweating, and confusion); and (4) bloody vomitus or tarry stool. Also note that demonstration of “free air” on radiological examination is highly indicative of a perforated viscus organ. An erect chest x-ray or an upright abdominal x-ray is by far the best initial diagnostic screening test.
GERD and Barrett’s esophagus are related to inappropriate relaxation of the lower esophageal sphincter.
Hiatal hernia predisposes to GERD and may causes herniation of the stomach into the thoracic cavity.
Crigler-Najjar Syndrome patients are unable to conjugate bilirubin. Unconjugated hyperbilirubinemia quite often causes death due to kernicterus.
The body and tail of the pancreas are situated posterior to the stomach. The quadrate lobe of the liver and gall bladder are both anterior to the stomach. The right kidney is situated posterior to the duodenum and small intestine. The right crus of the diaphragm is posterior to the liver.
An anal fissure is a small split or tear in the mucosa lining the anus. Anal fissures are extremely common in young infants, but they may occur at any age. Studies suggest that 80% of infants will have had an anal fissure by the end of their first year. The rate of anal fissures decreases rapidly with age, and fissures are much less common among school-aged children. I didn't know that they were common in infants.
Cryptosporidium = acid-fast protozoan that produces voluminous watery diarrhea without blood or mucus. It is very common in AIDS patients. Entamoeba histolytica (causes amoebic colitis), shigella, enteroinvasive E. coli, campylobacter, and cryptosporidium cause bloody diarrhea.
This question was about a woman who clearly had H. pylori infection and they asked what kind of cancer she had. I chose lymphoma but then switched to adenocarcinoma, finally changing back to lymphoma and got it wrong. I thought H. pylori causes MALToma, which is a type of lymphoma. Yes, the gastric cells are secretory cells, so if they became cancerous, it would be cancer of glandular cells (the "adeno" in "adenoma" = glandular cells), but H. pylori causes MALToma. So I don't think lymphoma is necessarily the wrong answer. I was stuck between lymphoma (my initial answer because the pt clearly has a history of H. pylori infection) and adenocarcinoma. The explanation:
Helicobacter pylori infection is associated with adenocarcinoma (accounts for almost 90% of stomach cancers). Note that adenoacanthoma is an adenocarcinoma in which some of the cells exhibit squamous differentiation.
The vagus nerve passes inferiorly from a plexus associated with the hilum of the lung. Injury to the vagus nerve--> decreased gastric motility. In the mediastinum, the vagus nerves pass immediately posterior to the roots of the lungs, while the phrenic nerves pass immediately anterior to them.
Dietary long chain fatty acids (more than 12C) are transported from the intestine to the adipose tissue in the form of chylomicron triglycerides. I remembered that from learning about cholesterol. Pretty sure they get transported across the intestines. I really have to review cholesterol. Ugh.
In a question, the pt had polyuria, pruritic skin rashes that appeared in one place and then disappear and showed up elsewhere, erythematous plaques and vesicles on her thigh, anemia, hyperglycemia, and increased ACTH. I wasn't sure what it was.
The patient most likely has necrolytic migratory erythema (NME) due to glucagonoma.
Glucagonoma is a rare pancreatic alpha-cell neoplasm that is mostly seen in pre-and post-menopausal woman. Patients present with marked increase in serum glucagon level, hyperglycemia, polydipsia, and polyuria. During the early stages, the condition may mimic symptoms of mild diabetes mellitus. A characteristic skin finding in these patients is necrolytic migratory erythema (NME). The majority of these tumors are malignant, and metastasis to the liver is not uncommon. Note that glucagonoma is often associated with MEN I, and serology of the patients often show increased plasma ACTH, MSH, serotonin, and epinephrine. Treatment includes insulin administration and surgical removal of the tumors.
The mechanism of NME is not well-known but it is postulated to be due to (1) direct damage of glucagon to skin that causes necrosis; (2) serious metabolic deficiencies that cause deficiency of epidermal proteins; and (3) autoimmune conditions that damage the skin. Glucagonoma is by far the most common cause of NME. Deficiency of zinc, fatty acid, and amino acids, liver diseases, hypoalbuminemia, inflammatory bowel disease, celiac sprue, and malnutrition conditions may also be associated with NME. Given that pancreatic alpha-cell neoplasm is by far the most common cause of NME, the non-pancreatic causes of NME (e.g. liver disease or zinc deficiency) are collectively known as pseudoglucagonoma.
#Intussusception#amebic colitis#wermer#wermer syndrome#hepatoblastoma#esophageal varices#zinc#phytate#picolinic acid#zinc deficiency#ascending cholangitis#PUD#Crigler Najjar Syndrome#cryptosporidium#diarrhea#adenocanthoma#adenoacanthoma#anatomy#NME#glucagonoma
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I just surrendered someone I “thought” was my TF of 31 year’s. I met someone in 2019, assuming it was another karmic partner. I hadn’t dated for 11 years. But I couldn’t resist his energy. He was also 13 year’s younger than myself. I don’t believe in dating anyone 5 year’s younger than myself & here I was fighting this energetic connection to this younger man like crazy. It took him a few months to get me to go out with him, to finally meet him in person. We met, thing’s were crazy with us. I told him I’d been waiting for someone for 29 year’s point, I knowit bothered him. I told him i was 100% sure this other person was my TF & I’d leave anyone for him if he ever came back to me again. I blamed myself for losing him in the first place, I wasn’t going to allow it to happen twice. Meeting this guy felt like I was repeating history because I was certain my TF & I were about to reunite when this guy pops up. This put a third person in between our budding relationship who wasn’t physically there or physically available. I continued to allow myself to feel the energy of this new guy I was only dating. We had an instant connection that I hadn’t experienced with anyone for many many year’s, it reminded me of what I felt for my first TF. The connection had it’s differences compared to the person who I thought was my TF. Like hearing him in my mind when I allow it, I never experienced that before. I feel like he’s listening to my every thought, which irritates me. I feel like I have no privacy. I dream about him all the time when I didn’t dream about my first TF hardly at all until recently. I started thinking for the first time that maybe I was wrong, that maybe this karmic partner was really my TF. I’d say it to myself then just as quickly dismiss it. I’d discuss it with my sister’s a lot. The energy only grew stronger as our time together grew. I healed many thing’s in my body during that time of my life, that they tell people are near impossible to heal. That includes hypothyroidism. Diabetes 2, metabolic syndrome, stage 3 fatty liver disease & the aggressive RA I had is now not as aggressive. I was also in & out of a wheelchair, walking with a cane occasionally, in 24-7 physical pain. I suddenly had energy I didn’t have in year’s, .y pain levels went down. My drs released me to physical therapy & I took off on a local trail fast walking after a month of physical therapy. I was done being indoors after isolating for many year’s, I wanted to be surrounded with nature. I ended up taking off over 100lbs. At first every step was painful. I remember feeling I wanted to meet this person who I had so much energy with as a better version of myself than I was. More in shape. When I was younger I used to wake up two hours early just to make sure I looked perfect. Because of being so physically ill for so many year’s, I can honestly say I no longer cared about my appearance as much, I was resigned to living the rest of my life being single. Then suddenly I meet this guy out of the blue who’s extremely persistent, very kind & he was bringing thing’s out in me I hadn’t allowed myself to feel for year’s. Including making myself as sexy as I could for him. I normally didn’t care what men thought, they could take it or leave it. I wanted this new guy to see exactly how beautiful I was, how I saw myself under all the weight I’d gained to protect myself from love. I couldn’t believe he’d chosen me, I was so out of shape, I was frumpy. Lol. That’s the truth. It was wonderful when we were together. But being apart was driving me nuts. And I’m NOT normally like that in relationships. I really try to make sure the other person has their space. He began giving me too much space. That upset me. I was feeling too clingy, that upset me. I couldn’t have him knowing that. So I continued to work out like a mad woman. Every time he saw me, I was smaller. When we took three months off, I came back to him an entirely different person than he’d met in February from August.
Idk what he thought about that… But it was fun showing him I felt sexy, I did it all for him. He never knew. I assumed a lot about him, I’m sure he did with me as well. That he was just a player, probably seeing other women too, playing the exact same game with them as he was with me. But then we’d get together & the energy was always there, it was undeniable. I just wanted more & he refused me. I started believing he was married. For all I know he was, he is now… How do we get passed that? I’m the type that believes in vows. They’re sacred. I was trying to deny what I was feeling. I believe he was too. You can’t date someone the way he was dating me & have it work. I think the term is popcorn dating? I began feeling like I was begging him for mere scraps. I started telling myself it was because of my age. Then that he deserved someone... Click here to read this complete article. Disclaimer : This article is originally published in SpiritualUnite.com. All the rights of content are owned by SpiritualUnite.com. We have published a part of the article with due credits and link to the original author and source.
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COMMENTARY: Treating Liver Disease During COVID-19: New Recommendations
What your doctor is reading on Medscape.com:
MAY 14, 2020 — The COVID-19 pandemic presents myriad challenges to hepatologists, gastroenterologists, transplant programs, primary care providers, and, of course, their patients. These frustrations are compounded by the fact that the virus’ impact on the liver is not yet fully understood.
In order to advise healthcare providers on how best to serve patients and their families during these unprecedented times, the American Association for the Study of Liver Diseases (AASLD) recently released Clinical Insights for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic. The authors of this freely available resource prefaced it with the disclaimer that it represents only their collective opinions and has not been subjected to the methodical rigor of a practice guideline. Instead, it is a “living” document that will evolve and be updated as new information becomes available.
Nonetheless, it offers valuable clinical recommendations and policies to mitigate the impact of the COVID-19 pandemic on patients with liver disease and the healthcare providers who treat them. Here are some of the takeaways that we have found the most useful at our liver care center.
The Novel Coronavirus’ Effects on the Liver: What We Know, What We Don’t
SARS-CoV-2 binds to target cells through a functional receptor, angiotensin-converting enzyme 2, which is present on biliary and liver epithelial cells. Therefore, the liver is a potential target for infection.
Early reports suggest a 14%-53% incidence of liver injury in patients with COVID-19. This estimate is based on observation of elevated aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels 1-2 times the upper limit of normal and modestly elevated total bilirubin levels early in the disease process. Liver injury in mild cases is usually transient and does not require specific treatment. However, rare cases of more severe acute hepatitis have been described. Reports of liver histologic changes have so far been limited, with documented nonspecific injury ranging from focal necrosis to moderate microvesicular steatosis with mild, mixed lobular, and portal activity.
The pathogenesis underlying such abnormal liver biochemistries is undefined. It may reflect a direct virus-induced cytopathic effect and/or immune damage from the provoked inflammatory response (cytokine storm/immune activation).
Continued
It is also not known whether patients with chronic liver disease such as viral hepatitis B and/or C may be more susceptible to liver damage from SARS-CoV-2, as was noted with the earlier SARS-CoV virus. Emerging data do suggest that patients with nonalcoholic fatty liver disease (NAFLD) may be at higher risk for severe COVID-19. It is not clear whether the risk is specific to NAFLD or to coexisting metabolic risk factors such as obesity, cardiovascular disease, and diabetes mellitus, all of which are associated with COVID-19 severity.
Assessing the Risk of COVID-19 in Our Patients
Taking these data into consideration, the AASLD document offers several recommendations.
The authors recommend that immunosuppressed patients (ie, those with autoimmune hepatitis and those post-transplant) should be closely monitored and prioritized for COVID-19 testing.
In addition, it should not be assumed that COVID-19 is the culprit in a patient presenting with acute liver injury. Other causes of elevated AST/ALT levels should be excluded, including viruses such as hepatitis A, B, and C, as well as muscle or cardiac injury, ischemia, and cytokine release syndrome. Similarly, for patients with autoimmune hepatitis or liver transplant recipients with active COVID-19 and elevated AST/ALT levels, do not presume disease flare or acute cellular rejection without biopsy confirmation.
It is also important to keep in mind that proposed COVID-19 therapeutic agents, such as remdesivir and tocilizumab, may in themselves be hepatotoxic.
The need to limit exposure of other patients and caregivers to a patient with COVID-19 is also emphasized. Therefore, transporting COVID-19–positive patients to undergo ultrasound or other advanced imaging should be avoided unless such testing is critical to management planning.
Given the potential for fecal-oral SARS-CoV-2 transmission, the AASLD has joined multiple other societies in strongly recommending that nonurgent procedures (eg, endoscopy, liver biopsy, transient elastography) be rescheduled.
Special Concerns Surrounding Liver Transplantation
One clear and immediate effect of the COVID-19 pandemic has been the decrease in liver donation and transplantation, an unintended consequence of which may be an increased rate of mortality of waitlisted patients.
Continued
There is limited information regarding the effects of SARS-CoV-2 infection in patients with decompensated cirrhosis or those awaiting liver transplantation. This makes the always complex decision as to whether to proceed with transplantation even more challenging.
Certain transplant centers may decide against providing organs to individual candidates at this time. The authors recommend that each center continuously assess the local situation and its impact. Special consideration could be given to high-risk waitlisted patients (ie, those with high Model for End-stage Liver Disease scores, risk of decompensation, or liver tumor progression). In addition, a reduction in organ recovery is expected because of COVID-19–related limitations on institutional resources and the evolving understanding of the risk of donor-derived disease transmission.
In order to limit the number of patients in the clinic, the recommendation is that centers evaluate only those patients with hepatocellular carcinoma or severe disease that need immediate liver transplant listing. For outpatients, the document supports the management strategy already employed by several programs: telemedicine in place of outreach clinics, judicious use of lab monitoring and imaging, and screening portals for patients coming in to the hospital.
Education, social work, dietitian, and financial consultation should also be conducted by video conference, telemedicine, or telephone. If possible, Internet-based education sessions for patients and family members can be deployed. We have found this approach to be well received at our institution.
There are additional recommendations for patients who have already undergone transplantation. It is postulated that because the immune response may be the main driver for pulmonary injury due to COVID-19, immunosuppression may, ironically, be protective. In fact, posttransplant immunosuppression was not a risk factor for mortality associated with the earlier severe acute respiratory syndrome (2002-2003) or Middle East respiratory syndrome (2012-present) outbreaks, but immunosuppression may prolong viral shedding in posttransplant patients with COVID-19.
Rapid pulmonary deterioration in patients with COVID-19 is postulated to be due to a systemic/pulmonary inflammatory response associated with increased serum interleukin (IL)-6, IL-8, and tumor necrosis factor-alpha levels. It is further hypothesized that reducing the dosage or stopping immunosuppressants may cause a flare in a patient with autoimmune hepatitis or precipitate acute rejection in a liver transplant recipient.
Continued
These knowledge gaps have raised many questions among our transplant team. Therefore, we welcome the guidance to not reduce immunosuppression for asymptomatic posttransplant patients without known COVID-19. For immunosuppressed liver disease patients who do have COVID-19, the authors suggest reducing azathioprine or mycophenolate, and minimizing but not stopping calcineurin inhibitor dosage.
Impact on Clinical Research, Patient and Worker Safety
Due to quarantine-related travel restrictions and potential supply chain interruptions, the US Food and Drug Administration and the National Institutes of Health have posted guidance documents for the conduct of clinical trials during the COVID-19 pandemic. Patient safety, which is of highest importance, should be used to guide decisions affecting the trial, including recruitment, patient monitoring, assessments, and investigational product dispensing. A related recommendation is to not initiate new clinical trials unless they meet the definition of “essential.”
Of course, ensuring the safety of all involved in the healthcare system is a paramount concern at the moment. The document provides advice/assurance to share with our patients, emphasizing the value of established prevention (hygiene, avoidance, travel restrictions), holding steady with immune suppression, and reporting all concerning symptoms.
There is widespread concern that the risks of exposing trainees to SARS-CoV-2 may outweigh the educational benefits. In order to allow trainees to meet regulatory requirements, the recommendation is to conduct all educational conferences via online platforms (eg, Zoom, Skype). After a few glitches, we have found this strategy to be very effective and well received. We have also followed recommendations to incorporate our trainees into telemedicine patient visits.
The SARS-CoV-2 infection rate of healthcare workers may be as high as 20%. In addition to protecting our patients, healthcare workers must take action to prevent COVID-19 infection and address the mental and physical well-being of our colleagues. As suggested in this document, we have staggered work shifts for physicians, providers, nurses, and staff, and created a “hepatologist/surgeon of the day” schedule.
As we all have learned, the strategies employed during this pandemic change daily, and we must adapt and adjust as new data emerge. I suggest that you visit the AASLD website for up-to-date COVID-19 resources.
Continued
And, of course, stay safe, stay sane, and stay sanitized.
William F. Balistreri, MD, is the Dorothy M. M. Kersten Professor of Pediatrics; director emeritus, Pediatric Liver Care Center; medical director emeritus, Liver Transplantation; and professor, University of Cincinnati College of Medicine, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center. He has served as director of the Division of Gastroenterology, Hepatology and Nutrition at Cincinnati Children’s for 25 years, and frequently covers gastroenterology-, liver-, and nutrition-related topics for Medscape. Dr Balistreri is currently editor-in-chief of The Journal of Pediatrics, having previously served as editor-in-chief of several journals and textbooks. He also became the first pediatrician to act as president of the American Association for the Study of Liver Diseases. In his spare time, he coaches youth lacrosse.
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Liver Diseases & Causes of Liver Failure
There are a bunch of liver disorders which might require the need for a liver transplantation. In grown-ups, ESLD or cirrhosis is the initial reason for which a liver transplant is required.
Liver disorder comprises an array of diseases that can vary in severity. From light injuries to severe liver cirrhosis, there are any conditions which need immediate medical attention. Untreated liver damages prove to be a gateway towards cirrhosis or liver scarring – also termed as end-stage liver disease.
Here are some causes of liver cirrhosis
Hepatitis (A, B, C, and others) which may affect the functioning of liver cells.
Wilson’s disease – also termed as a disorder of copper metabolism.
A genetic mistake with a lost enzyme that may result in liver disease – often referred to as Alpha-one anti-trypsin deficiency
An inherited metabolic disorder known as Glycogen storage disease (type I, III, IV)
A disorder of tyrosine metabolism referred to as Tyrosinemia
Alcoholic liver infection along with Drug-induced liver infection which is caused due to extreme consumption of drink/drugs causing irrevocable damage to the liver.
Nonalcoholic fatty liver disease resulting in extra fat in the liver owing to obesity, high levels of cholesterol or triglycerides accumulating in the liver.
Initial biliary atresia, also known as extrahepatic ductopenia – a congenital disease where the bile ducts hold forming properly resulting in narrow, blocked, or absent ducts.
Autoimmune liver diseases – where the immune method stages an attack against the liver
A condition known as Hemochromatosis which is characterized by excessive iron deposits in the liver
End-stage liver disease (ESLD) or cirrhosis
Cirrhosis is a last-stage liver disease that is caused as a result of sustaining permanent damage or scarring of the liver. When an individual has cirrhosis, it means that the scar tissue (fibrosis) has damaged or substituted the healthy tissue or liver cells. Extra time, when scarring has affected a significant part of the liver, it is a situation which is referred to as cirrhosis.
This scar tissue stops the liver from working at optimal levels ultimately causing loss of liver function. It requires to be mentioned that even if almost 70 percent of the liver is damaged, the liver can renew and improve itself in just a matter of a few weeks. However, a liver affected from cirrhosis can’t renew or re-grow which eventually results in the liver losing its capability to function properly. Seriously still, this is often a progressive condition and usually irreversible as well. What this also means is that no kind of medicines can change or treat this disease. This situation which results in the loss of liver function or organ failure can be described as End-Stage Liver Disease (ESLD).
Liver cirrhosis has also been linked as the biggest risk factor for primary liver cancer (hepatocellular carcinoma), which has rapidly become the leading cause of cancer death across the world. Another issue that arises due to ESLD is the reduction in brain function. This is caused as a result of the build-up of toxins in the blood – owing to the liver not functioning – which can confuse. The resulting signs can cause irritation and unresponsiveness, eventually spiraling out of control and can even cause the affected individual to slip into a comatose state. Scarring can also stop the liver from producing enough clotting factors, which can cause bleeding and bruising.
Signs and symptoms associated with liver disease
Individuals suffering from cirrhosis might not showcase any symptoms especially in the early stages of cirrhosis. However, with time as the condition worsens, it can cause the following symptoms, including:
Tiredness or Fatigue
Loss of Appetite
Excessive sleepiness
The buildup of fluid in the abdomen leading to swelling
Unexplained weight loss
Easy bruising and bleeding
Presence of small red spots and appearance of tiny lines on the skin also termed as spider angiomas
Loss of muscle mass
A state of constant drowsiness and confusion owing to a build-up of toxins in the gut
Yellowing of the skin and the eyes as well as dark yellow urine (Jaundice)
Heavy nosebleeds.
Severe and constant Itching all over the body
Swelling from the buildup of fluids in the hands and feet (edema)
Bleeding as a result of the enlarged veins present in the digestive tract.
Vomiting of blood and presence of blood in the stools
More potential processing of alcohol and drugs resulting in improved consciousness when these substances are consumed.
In the case of individuals suffering from only mild liver damage, these symptoms might not manifest itself and may need medical or endoscopic therapy. If the above symptoms were to occur, it’s termed as decompensation or the failure of an organ. By the time individuals are diagnosed with the above symptoms, it might already be too late. Primary diagnostic tests in
cirrhotic patients also reveal the following:
Elevated levels of bilirubin
Low albumin levels
High prothrombin time (international normalized ratio)
Thrombocytopenia (low platelet count)
Acute or fulminant liver failure
Acute liver failure (ALF) is a few but a destructive situation which can show to be life-threatening as well. ALF can cause a sudden, progressive, and severe liver dysfunction over just a some days or week which can culminate into multi-organ failure and eventually death. It can affect an unless ordinary individual and even people without any preexisting liver diseases either. This improves in the rapid but severe deterioration of the liver – while affecting its functioning – within no time. Early symptoms of ALF need to be closely monitored including the onset of jaundice, a feeling of confusion or drowsiness which eventually results in the individual slipping into a comatose state.
It also requires to be suggested that patients undergoing from ALF can die within days if they do not get a liver transplant unlike individuals suffering from the chronic liver infection who can survive for a longer time-frame while awaiting liver transplantation.
Some infections which can cause acute liver failure are as follows:
Liver disorders leading to infections created by hepatitis A virus (HAV) or hepatitis E virus (HEV)
Side effects of certain medications such as anti-tubercular drugs, paracetamol & even Ayurvedic medicines
Acute fatty liver of pregnancy (AFLP)
Dr. Palnitkar Liver & Gasrto Care Clinic for Liver Care & Transplantation
At Dr. Palnitkar Clinic for Liver Transplantation, the experienced team of liver specialists ensures the best treatment for your liver and the associated organs such as the pancreas, biliary tree and gall bladder. When these organs are bothered with normal diseases including Hepatitis A and B, fatty liver, cirrhosis and even cancer, the hepatologists rise to the occasion to diagnose and treat the diseases in the best possible methods.
Liver Transplantation team involves very qualified and experienced hepatologist who are equipped with the agility and precision to conduct liver transplants when this incredibly hardworking organ gives up functioning to its maximum capacity.
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Top Healthcare Financing Company for Flexible Patient Financing during Bladder Cancer Treatment
Financial aspects of bladder cancer treatment of bladder
Cost analysis of bladder cancer is a crucial aspect. During the progress of treatment, methods like chemoradiation, chemotherapy, radiation, and supportive care can lead to heavy medical bills. Bladder cancer treatment is expensive. On average, the cost of medical intervention can range from $34,000 to $75,000 (USD). Its cost differs depending on the stage, and it can put a significant toll on your wallet. The average price of surgery, chemotherapy, and radiation therapy ranges between $5000 to $100,000 or more, depending upon the stage of bladder cancer. Even though most of these clinical costs are supported by healthcare insurance, but patients still end up paying large out-of-pocket medical bills and copays. Hence, it is always advised to turn to top healthcare financing companies in the US.
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Bladder cancer - What is bladder cancer?
Bladder cancer occurs due to the abnormal growth of cells in the bladder lining. With the progression of time, these unhealthy growths form a tumor along with the lining of the bladder. It usually has the potential to spread into the bladder muscles. Depending upon the spread of the cancerous cells, bladder cancer is divided into two subtypes viz. non-muscle-invasive-bladder-cancer and muscle invasive-bladder-cancer.
Causes and symptoms of bladder cancer - How do I know if I have bladder cancer?
The most common symptom of bladder cancer is blood in urine, painful urination, and pelvic pain. Exposure to chemical and radiation, excessive use of intoxicating substances, chronic infections are considered as causes of bladder cancer.
Stages of bladder cancer - Are there any stages of bladder cancer?
Stage-0 bladder cancer - This stage is also known as non-invasive carcinoma. At stage 0, the bladder cancer is localized to the hollow center of the bladder wall. The cancerous cells are only found in the inner lining of the bladder.
Stage-I bladder cancer - At stage I, cancer grows into the connective tissues under the layers of the bladder. However, the lymph nodes and muscles layers are devoid of the cancerous cells.
Stage-II bladder cancer - At stage II, the cancerous cells breach the muscular layers of the bladder wall. However, a distant penetration into the fatty layers of the bladder is yet to be attained by the cancerous cells.
Stage-III bladder cancer - In this stage, the cancerous cells are found in the layers of the fatty tissue of the bladder with a possibility of the cancerous cells reaching the prostate, seminal vesicles, uterus, or vagina.
Stage-IV bladder cancer - In stage IV, the bladder cancer grows into the pelvic wall. During this stage of the disease, it spreads to the nearby lymph nodes and organs such as bones, liver, or lungs as well.
Treatment advances for bladder cancer (Stage 0, I, II, III, and IV)
There is standard care available for the treatment of bladder cancer. The major type of bladder cancer treatment includes chemotherapy, immunotherapy, radiation therapy, surgery, and targeted therapy. If detected early, bladder cancer is subjected to cystectomy (partial bladder removal).
For slow-growing tumors, weekly intravesical chemotherapy may be followed by your healthcare provider. For all the remaining stages, transurethral resection (TURBT) is recommended as the first line of treatment. To deal with the cancerous cells, which have penetrated the nearby tissues and organs, radiotherapy and chemotherapy are recommended.
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Denefits patient financing options are free from both hard and soft credit checks. Our payment plans are available with flexible financing terms. We ensure a 100% approval rate. Our policies are fully transparent, and there are NO hidden fees. When the traditional healthcare financing options fail to fulfill your medical financing needs, Denefits can help you to get through your hard times.
Along with that, Denefits also has a unique feature of Social Healthcare Payments™, which can be used by the patients to raise funds for their medical bills. With our value-based services, we are sure to have a long term and fruitful relationship.
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Derry, New Hampshire Celebrates 20th year with Relay
June 16, 2017
At the Derry, New Hampshire event I was able to chat with a few people on the rainy evening event. There was a good turn out with all that rain.
I met Jo Ann Palermo, a retired post office worker, who has always been very health conscious. She worked the 3 to midnight shift sorting mail, ate only half of her dinner so she could use half of her time to walk (rain or shine), doesn’t drink or smoke. She bicycles, walks, hikes, cross country skis and camps. She has been very cognizance of her health so she was very surprised at her cancer diagnosis since she sees so many people who eat and drink unhealthy thing but are not afflicted with the disease.
Jo Ann Palermo, 6 year ovarian cancer survivor
6 years ago, at the age of 65, Pat was diagnosed with ovarian cancer. As her job as a trainer for the post office was being phased out she was moved to unloading trucks. She found the new job was very physically challenging. After about 6-7 months she noticed she was very tired and had to use the restroom more often to empty her bladder. Because of the constant need to use the restroom she was told she would have to get a doctor’s note. She made an appointment and her doctor said he wanted her to see a urologist. When she made the appointment, there was a snow storm so by the time she got to see the doctor is was about 3-4 months later. The doctor thought it was a bladder issue so he sent her for more tests.
After the results came back it was discovered that Jo Ann had ovarian cancer.
She is a strong woman of faith who found that she has grown much closer to God since dealing with having cancer. Her daughter bought a cabin so she could spend time at it. She has found that cancer has made her life better because she looks for more of the good now. With 3 kids (2 girls and a boy) and 6 grandchildren she finds she is so much closer to them now. Her son changed his days off so he could sit with her during her chemo.
Jo Ann has a great saying “Cancer invaded my body but it can’t invade my soul”, and people who have been told they have cancer start fighting the moment they hear the words “you have cancer”. We don’t realize how much we fight through all the phases of diagnosis, surgeries, treatments, etc.
Jo Ann continues to live a healthy lifestyle. She is doing well and enjoying life every day!
Carol, a diabetic, had to have her finger amputated in the middle of January 2016. She mentioned to the nurse practitioner that she had severe stomach pains as well. The nurse said that she had a fatty liver from eating too much fried foods. Carol didn’t agree. She ended up in the hospital in July 2016 from severe pain, especially after she would eat even a little bit. By the time they diagnosed her it was stage 4 liver cancer.
Carol, liver cancer survivor, and one of the Santa’s that attended the event
Her doctor ordered a barrage of tests to see what exactly was going on. Because the ultrasound didn’t look good the doctor ordered even more tests.
A wonderful woman, Olive, that Carol has been living with helped her through a lot of her diagnosis and treatments but she passed away this past April 14th just before she turned 90 so Carol is dealing with her cancer without a strong support system.
In the early 80’s Carol’s father had lung cancer and was given 3 months to live but Carol says he was a stubborn man. He survived 18 years! She figures she is as stubborn as her father was. He died March 9, 1999 at the age of 63. Her parents were so close, with such a great love for one another that her Mom passed away 13 days later.
Now Carol is going through chemo and says you really find out who your friends are. Olive was a dear friend. Carol worked with her 30 years ago, so they had been good friends for a long time. She misses her and finds that the people who are true friends are the ones that try to help her. Carol drives herself to her treatments but says the people at the clinic are awesome. Cancer is hard enough to deal with but your support system makes a huge difference as well.
Doreen was 48 when she was diagnosed with breast cancer, 9 years ago. She is one of 10 children and her mom was one of 10 children but nowhere was there any cancer in the family. Doreen has 2 girls of her own so, because of her diagnosis, they need to be more aware now. She went to the doctor for her checkup and he found a lump but he never said to do anything about it. Doreen couldn’t feel the lump so she didn’t really think about it after she left the doctor’s office, especially since she isn’t the type of person who puts herself first.
Doreen, 9 year breast cancer survivor
It was around thanksgiving and things were busy in her household, especially with a 9 and 11-year-old girls and a husband that works “crazy hours”. When she told her husband about her strange experience at the doctors, he asked if she needed to go get a mammogram. Doreen already has an appointment in February and the doctor didn’t say it was urgent so she waited. Her husband was gone on a job for 4 months so Doreen was busy taking care of their girls, the house, the snow, etc. She did keep her commitment to get the mammogram (even though she contemplated not going because she was tired). It was about 4 or 5 days later as she was getting ready for the day when she was thinking “all must be well for another year” because she hadn’t heard from anyone. Then the phone rang.
Doreen had to go back in for more tests. They did a partial mammogram and an ultrasound and told her they did see a lump and wanted her to go to her surgeon. Doreen was completely thrown off because she doesn’t have a surgeon. She wanted to go home and check her insurance. It was tough because no one said “these are the surgeons we recommended”. Doreen said she picked her surgeon on a whim, no one recommended a specific surgeon and she didn’t know any of the ones available. He was a nice man but he was a general surgeon, not a breast surgeon.
Doreen asked for him to leave her some information and they gave her breast cancer pamphlets. It was scary because no one told her it was cancer. Around Valentine’s Day her husband came home for a few days and Doreen finally told him what was going on. As many of us can imagine he was devastated. As much as he wanted to stay Doreen is one strong woman because she sent him back to work.
The surgeon did a lumpectomy, but a few days later she received a call saying she needed to come back because they didn’t get clear margin. At this point Doreen decided it was time to find a breast surgeon. She had a tough time during recovery. She didn’t want to be a burden, her husband was afraid he’d bother her, so Doreen felt a bit isolated. It’s so hard because everyone believes they are doing what is best.
When she went for a second opinion they found another lump that no one had seen or felt so they suggested Doreen get a mastectomy. During the discussions with her husband she decided to get breast reconstruction. Recovery was tough, but luckily Doreen says her husband was home.
Originally chemo was suggested so Doreen and her husband prepared for these treatments however when they went the morning of the first treatment they decided not to do it. Doreen’s husband didn’t like the idea of chemo so they cancelled the appointment that morning. They told the doctors that chemo was on hold until they could get more information.
After some research Doreen decided to have some testing on the cancer tissue. Fighting to get the testing done was crazy but she was persistent. She went through appeal boards and review boards but she won! The results came back on the tissue and it showed that chemo wasn’t needed!!! Doreen fought through this whole situation as the strong one, she is one tough cookie.
Relay is a part of the family as well. Her daughter, Victoria, started a Relay team at her college, St. Rose in Albany, and is extremely involved. On her fundraising page Vicki says “When I was 10, my mom was diagnosed with breast cancer. I've spent the last 9 years Relaying in the hopes that no other little kid has to fear growing up without their mom. This year, I'm honored to serve as the President of Colleges Against Cancer and once again work to put this all together. We celebrate, we remember, and we fight back against this terrible disease and the people it affects.” You can also see the St. Rose Relay page at https://www.facebook.com/SaintRoseRelay/
Doreen is healthy now and has even started a 5k training program. She still reminds every one of the importance of mammograms and taking care of their health!
Tom has an unusual story as well, a bit more unusual than some that I have heard. Tom loved to play street hockey but took a hit to the head (tough player) and fractured an orbital bone several years ago. He also had developed a hernia when he played in a memorial game for his uncle. He went to his primary doctor and was told to get an ultrasound of the hernia. As soon as he had finished the ultrasound and arrived home the phone was ringing. The doctor told him and his mom to get back to her office right away. She said that behind the hernia were 4 tumors – a 22 cm tumor on the right and left side of the hernia and 2-10 cm masses on his spleen. It was strange because Tom had also developed high blood pressure.
Dr. Anne Thomassen, Tom’s primary doctor, sent him to Dr. Lata Thatai for the biopsy. The results were surprising to the doctor so she sent him for a second biopsy. She was still astonished by the results so she suggested they would do the hernia surgery first and retest the tumors. When Tom came to the office, thinking he was going to start some type of treatments, Dr. Thatai said the pathology report indicated something she had never seen. Tom had both B-cell and T-cell Hodgkin’s and Non-Hodgkin’s cancer in each of the 4 tumors. One is an aggressive and the other is a non-aggressive type of cancer. Dr. Thatai contacted a doctor at Brigham & Women’s Hospital to get some treatment ideas but was told not to treat the cancers at the same time. Dr. Thatai didn’t want to take a 50/50 chance on curing one of the cancers but not the other type so she contacted another doctor to get more advice. She contacted Dr. Jeremy Abramson at Massachusetts General Hospital. Dr. Abramson asked Tom if he’d be willing to take all the Hodgkin’s chemo drugs at the same time for 6 rounds of chemo. Tom accepted. Dr. Thatai wanted Tom to do 8 rounds of chemo but he did 6 rounds of chemo since the drugs are VERY strong.
Tom also shared how his faith has helped him through his journey through cancer. He said “I had asked my priest for the sacrament of the sick, and went to a healing mass, where they used (for the first time) the healing oils from St. Joseph's Oratory, the same holy oils from the same place that Brother Andre Bessette (now known as Saint Andre) came from in Montreal. I have known of the holy oils and miracles since I was young, and was stunned when I saw the bottles we always got from St. Joseph's.” He had two moments before he started chemo that he feels these faith-events affected in his treatments and cure.
Although he has some health issues now that are separate from the cancer Tom feels his is doing well. Tom has lost special people in his life to cancer – an aunt and a friend. He attributes his 5 years cancer free status to Dr. Thatai and Dr. Abramson (and I believe Tom’s tenacity in taking multiple chemo drugs to destroy 2 separate types of cancer at the same time).
Bianka Beaudoin, Community Manager for American Cancer Society’s New England Division, has been working for ACS for 6 years. Bianka relays in memory of her father. She is very passionate about Relay! I appreciate the love of someone special in her life that drives her (as it does so many of us).
Bianka Beaudoin, Community Manager for American Cancer Society’s New England Division
Bianka signing the shirts
While I attended this event, Derry was celebrating their 20th year for Relay for Life. Even though the weather was a bit damp, the spirits of the people at this event were not….they were exhilarating, supportive, appreciative, and welcoming.
Every event I attended in the last few weeks were wonderful, as usual. I am so blessed to be able to attend the Relay’s and be welcomed by the people who have been touched by cancer. I am honored to be able to share their stories.
More to come soon!!!
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What is Ketosis?
Ketosis is a metabolic state in which fat provides most of the fuel for the body. It occurs when there is limited access to glucose (blood sugar), which is the preferred fuel source for many cells in the body.
Who is a Ketogenic Diet ideal for? A Ketogenic Diet is ideal for both humans and dogs suffering from various health issues like treating and curing diabetes, skin rashes, hot spots, itching and almost all allergies, controlling seizures, and cancer. It can also be used with healthy humans and healthy dogs to help prevent future sickness.
What exactly is a Ketogenic Diet? A Ketogenic Diet is a high fat, moderate to low protein and low carbohydrate diet.
What is a 2:1 Ketogenic Diet? 2:1 refers to the specific type of ratio that compares the amount of fat to the amount of protein and net carbohydrate. A 2:1 ratio means for every 2 grams of fat, there is 1 gram of combined protein and net carbohydrate. In terms of percentages this equates to 82% of calories from Fat and 18% of calories from Protein and Net Carbohydrate.
How long should my dog stay on a 2:1 Ketogenic Diet? There are many factors that come into play here that will determine how long your dog should stay on a 2:1 ketogenic diet. Depending on the health of your dog, and their current metabolic markers, he or she may be on this ratio diet for a number of months. Once we are comfortable with their metabolic markers, we may suggest a ratio change and start throwing in some higher protein (1:1 ratio) days. This will help prevent muscle loss that often is associated with a low protein diet.
How long can my dog be on a Ketogenic diet? If your dog is suffering from some form of metabolic disease, like cancer, epilepsy, or diabetes, it would probably be a good idea that he/she remains on ketogenic diet. Also if your dog is suffering from an autoimmune disease like allergies, lupus, skin allergies or even arthritis, it would be a good idea that they remain on a ketogenic diet as well.
What is the long term effects of a Ketogenic diet? One of the most common long term effects of a ketogenic diet would be weight loss. Caloric intake should always be closely monitored and adjusted to meet the nutritional needs of the dog.
Can my dog eat this diet while on chemo or radiation? Yes they can. As a matter of fact, a ketogenic diet can improve the outcome of these treatments as well as mitigate the harsh side effect often associated with standard of care therapies.
What is 70/30 Ground Beef? Meat is typically labeled by percentage of fat. You’ll see 96/4, 90/10, 80/20 sometimes you’ll even see 75/25 and all that means is the percentage of lean meat to fat content. We recommend using 70% lean meat and 30% fat content because it is a 2:1 ketogenic ratio. You can ask your local butcher or meat dept. if they can make you a 70/30 ground beef if you don’t see it at the store. If you are absolutely not able to get anything less than an 80/20 or 85/15 meat, please let us know and we can give you the additional amounts of fat that we’d like you to add into the meals.
Does the beef have to be grass-fed? If you can afford grass-fed beef, then by all means buy it, because it is a better option for your dog. What a cow eats directly effects the types and level of nutrients you get from eating meat from that cow. Meat from a grass fed cow is loaded with even more nutrition then a cow fed a corn or grain-based diet. At the end of the day it call comes down to what you can truly afford.
What about bacteria and pathogens in the meat? Raw meat should be handled with the same safety precautions you use when you prepare burgers or steaks on the grill. There is no risk of contracting GI parasites from USDA-inspected, human grade meat. If you are still concerned, you can freeze the meat for a few days before you feed it to your pets. Please make sure you are washing pet bowls after feeding and sanitizing eating surface regularly. Also make sure your hands are clean when handling all raw meats.
Is beef the only meat I can feed my dog? No, you may feed other meats, but we always suggest starting with the fattest cuts of meats available to you. Meats like Chicken, Turkey, Venison and Elk are very lean and high in protein, so in the beginning stages if your dog is on a higher ketogenic ratio diet, we suggest you try stay away from those. If you can only get access to leaner cuts on meat like those mentioned above, you will need to add an fat source (fat source list mentioned below) to the meals in order to meet the suggested ketogenic ratio. Also I want to mention that if you don’t see a certain cut of meat it in the store coolers, ask the butcher if he can prepare it for you (most of them will).
What fat sources do you use? Besides the fats found in the beef we use, we rotate the fats source often as it is healthy for them to get a variety of fats in their diet. Rotation also helps prevent our dogs from developing an aversion to a certain fat. We suggest that you rotate fat sources from week to week. The fats sources we suggest are the following:
Monounsaturated Fat Sources: Avocado Oil, Olive Oil, Avocado Mayo. Saturated Fat Sources: Coconut Oil, Red Palm Oil, Ghee, Kerry Gold Unsalted Butter, Unsweetened Coconut Cream and Heavy Whipping Cream.
What about the risk of fatty liver disease with the high amount of fat consumption? Your dog will not develop fatty liver disease from the high fat consumption of the Ketogenic Diet. Fatty liver disease is often the result of abnormal bile flow in the liver and deficient hepatic function. Serious deterioration of the hepatic function can affect the liver’s capacity of detoxifying the bloodstream. Therefor toxins accumulate in the body and can cause further complications.
What vegetables can I give my dog? Now for the fibrous veggies, you can choose any of those listed below, but make sure you finely dice them up or puree them and then mix them up good in the food before you feed them. Please stay away from other veggies sources due to their high carbohydrate content.
Fibrous Veggies: Brussel Sprouts, Green Beans, Cabbage, Broccoli, Asparagus
My Vet suggests that I do not feed RAW. What do I do? Most vets are anti-raw diet due to the threat of bacteria or salmonella. If done properly you will have zero issues with either bacteria or salmonella. Also freezing the meat for a few days before serving can successfully avoid exposing your raw fed pet to parasites.
Can I cook the food? We do not recommend that you cook the food. Dogs have the proper gut bacteria and enzymes to naturally break down RAW food. Also cooked animal fats can lead to pancreatitis, organ failure, and can be deadly if left untreated.
Why is the food measurements you gave me is in grams? We want to be very strict on the caloric intake of your dog, so it is best to measure in the food in grams. If you don’t already own one, you’ll need to purchase digital food scale which will help you make sure you are delivering the exact amount of food suggested.
Are these food measurements correct? This doesn’t seem like a lot of food. Yes, the measurements are correct. The standard kibble diet is roughly 30 calories per pound. This is the #1 reason that approximately 25-30% of the general canine population is obese in North American. Unless the dog is already extremely lean, we start most dogs at 15 calories per pound. This allows us to get the dog into a metabolic state to fight disease. As weight fluctuates, we will make the necessary caloric adjustments.
Why Calorie Restriction? Excess body fat – or obesity – is also linked to cancer in dogs. The precise link is not yet completely defined, but new research has shown that fat cells secrete a chemical called adiponectin, which actually lessens the development of cancer cells. Fat cells secrete much less adiponectin when the body has excess fat in storage, which happens in a heavy dog. Fat cells secrete more adiponectin when the fat cells are being burned for fuel, which happens in a leaner dog. During a ketogenic diet, the dogs are burning fat for fuel.
My dog has very loose stools since starting the Ketogenic Diet. How can I fix this? When changing from a kibble based diet you many experience a short time when your dog has very loose stools. This is due to the sudden change their diet. This will eventually go away as they adapt to the consumption of this higher fat diet. You can add a teaspoon of chia seeds to their meal if they are experiencing diarrhea.
How do I know if the diet is working? The ketogenic diet is the only diet that you can validate with a simple blood ketone test. If the blood ketone test shows 0.3mmol or higher, then the diet is working.
What Glucose/Ketone reader do you suggest? We suggest the Precision Xtra blood glucose and blood ketone reader. You can purchase it on amazon.com. Also make sure that you buy both blood glucose and blood ketone strips.
Where is the ideal location to draw blood to test both glucose and ketones? To draw blood, you can use the side of one of the pads on the paw or the loose skin on their front elbow.
How often do you suggest that I test blood glucose and blood ketones? We highly suggest in the beginning you test blood levels every other day, right away in the morning before you feed them their first meal. Once we see numbers consistently where we want them to be, we can back off a bit and test twice a week (Mondays and Fridays).
What are the numbers we want to hit for blood glucose and blood ketones? Blood Glucose: 75 mg/dL or lower Blood Ketones: 0.3mmol or higher
I recently discovered Ketostix (urine ketone strips). These are much cheaper than the blood ketones strips. Are these ok to use? Ketone urine test strips truly will only work for the first few weeks of a ketogenic diet. In the early stages of a ketogenic diet your body will produce small amounts of ketones, but since your body doesn’t know how to use them yet as fuel, your body will pass these trace amounts of ketones in your urine. It is not until your body has burned off all the glucose that it will start to use the ketones as a fuel source. This is often referred to at keto adapted. Once keto adapted, ketones will no longer be present in your urine. So you can see these urine strips are not the most accurate means to measuring ketone levels.
My dog is losing too much weight, what do I do? The thing about the ketogenic diet is that once in ketosis, the body switches into fat burning stage. The end result of this is weight loss. While this is normally a good thing, we don’t want them losing weight at a rapid pace. Closely monitor your dog’s weight and if they are losing weight too rapidly, please let us know and we can make some dietary adjustments.
My dog doesn’t want to eat their meal. What do I do? It is perfectly ok if your dog misses a meal or even a few meals. They may not be interested and/or even hungry at the moment. If they are not interested, place the meal in the fridge and try feeding at a later time. Please don’t feel like you have to force feed them. Your dog should eventually eat when they are hungry. Often if you exercise them, they’ll eat afterwards. Now, if it has been multiple days and they still haven’t eaten, let us know and we can offer a few tips to try to get them to eat.
Speaking of exercise, how often should my dog get exercised and what exercises do you recommend? As far as metcon (Metabolic Conditioning) is concerned we like to give our dogs (2) 20-30 sessions per day. We like to get them running and get their heart rate up so if possible I’d like you to do the same. Even a long game of fetch for one of the sessions would suffice.
Exercise is also a very important part of our program and works hand in hand with our ketogenic diet protocol. The goal is to get these doggies into a regular exercise schedule daily to increase heart rate, burn calories and stimulate their mitochondria. This keeps insulin low and helps battle their cancers.
What treats can I give my dog? I know you’re probably wondering about what type of treats are ok to feed your dog. To be honest with you, we do not feed our KPS doggies treats. All of the calories our dogs get are in the two meals we feed them. Now I would try to avoid feeding treats as they can easily add a bunch of extra calories to their diet, not-to-mention many of them are full of carbohydrates and protein. Adding these can in fact prevent us from getting your dog into ketosis due to spiking their glucose. It is ok however to give your dog a bully stick once a week to help keep his teeth clean. Also if you must give them a treat, try freezing a tablespoon of coconut oil or unsalted butter in a hollow bone or Kong. Just make sure you give this to your dog outside or on a hard surface so it doesn’t make a mess on your carpet.
Are there any Supplements I should give to my dog? You may want to deliver calcium, potassium, magnesium and an omega 3 supplement with each meal as well as a good prebiotic, and probiotic. We give our doggies the following: Garden of Life Prebiotic Fiber, LivPro Probiotic Fiber, and Yes Oil. But you can go online and purchase similar products on amazon.com. Just do a simple search and you should find a bunch.
** Please avoid giving your dog a multi-vitamin. These contain both Iron and Folic Acid which can feed cancer. **
Suggested Supplement dosing: Probiotic Fiber: 1g per 50 lbs twice a day Prebiotic Fiber: Small dogs: 3.5g, Medium and Large dogs: 6g once a day with AM meal Yes Oil: 0.03mL/lbs twice a day
Why plant based omegas compared to fish/krill? The reason we don’t use fish or krill anymore is because you can’t convert direct EPA DHA into what the body needs. You need to have the parental oil’s which are things such as coconut oil, flax borage oil or evening primrose and high oleic sunflower oil as the 3, 6 and 9 Omega oil’s to be able to make our own…these oils are needed as the precursors. Less than 1 percent is converted to EPA and DHA. So we need the parent oils to convert.
The human body does not produce significant amounts of EPA or DHA on its own, so you must get these important nutrients from Yes supps or Udos (as brand examples).
There are others, but we’ve checked into these companies and their processing of the fats.
And also too often people stuff themselves as much as I can with omega-3’s and you really need the balance of six and nine to make everything work and be able to convert appropriately too much omega-3 is actually bad for you which the general population doesn’t know quite understand yet but more and more is coming out about that we actually need a lot more omega 6 than people realize but 6 from the right places.
Are there any other supplements that are safe for my dog on a ketogenic diet? You want to be careful when selecting additional supplements to give your dog while they are on a ketogenic diet. One reason for this is we don’t want you giving them a supplement that will prevent them from getting into ketosis. There are many supplements that can raise blood glucose levels, so before you give it to them, do some research and/or ask your Vet for advice. Turmeric, Turkey Tail Mushrooms, and Metformin are a few of the safe ones to give them.
My dog has seizures. Will they benefit from a ketogenic diet? Yes, they will most likely see a benefit from eating a ketogenic diet. Often you may even be able to lower the dosage of seizure medications.
Will a ketogenic diet help a dog with diabetes? Yes. If you follow the diet properly and stop feeding your dog non-fibrous carbohydrates, you will be able to lower your dog’s blood glucose numbers significantly. Often our dogs at KetoPet have blood glucose in the mid 50s to low 60s.
Will a ketogenic diet help a dog with arthritis or joint issues? Yes. A diet full of high glycemic carbohydrates will cause a lot of inflammation in the body, especially in the joints of older dogs. Eliminating these carbs and increasing the consumption of healthy fats will often eliminate a lot of the inflammation and joint pain.
What are your thoughts on CBD oil. Can I give to my dog CBD oil? We have never used CBD oil with any of our dogs at KetoPet Sanctuary and because of this we cannot validate its efficacy. If you still feel this is something you want to try with your dog, we highly recommend that you discuss this decision in detail with your vet.
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PARENT Essential Fatty Acids (DPAs, ALAs, EPAs & DHAs)
Essential fatty acids have undergone extensive studies with cancer and their potential anti-inflammatory effects on the body. In a recent study out of Finland, Jyrki Virtanen, from the University of Eastern Finland, analyzed blood levels of omega-3 fatty acids, as well as C-reactive protein (CRP) – a marker of inflammation, in Finnish men, ages 42 to 60 years. Results showed that is omega-3 levels increased, CRP levels decreased. Specifically, docosapentanoic acid (DPA) and docosahexanoic acid (DHA) increase significantly, whereas no change in levels of eicosapentaenoic acid (EPA) or alpha-linolenic acid (ALA) were observed. The study authors conclude that: “Serum [omega-3 polyunsaturated fatty acids] and especially the long-chain [omega-3 polyunsaturated fatty acids] concentration, a marker of fish or fish oil consumption, were inversely associated with serum [C-reactive protein] in men.”
Essential fatty acids are a great anti-inflammatory fat that everyone needs to consume. How much is enough? First understand that farm-raised salmon and other fish are NOT a good source of Omega-3’s. Do NOT buy fish that are farm-raised; these are fed prepared fish foods and not natural. To get EFAs from food, eat cold water, ocean caught fish that are products of their natural environment. DO NOT take supplements of fish oil; ONLY use PARENT oils (which are cold pressed seed oils – I list the source to buy below). You must spend the money and purchase a good brand that ensures little to no contaminants and has a reputation for quality.
Because omega–3 fatty acids are in shortest supply in the typical American diet and have been so imbalanced in most people for decades, I always recommend you obtain EFAs from a PARENT source. This means the oils are from unadulterated sources that are from sources that contain the ‘parents’ of both Omega-3 and Omega-6. These ‘parent essential oils’ (PEOs) are Linoleic Acid and Linolenic Acid. This is one of the simplest, safest, yet most effective steps you can take to quell chronic inflammation in your body. I also recommend that everyone include a small handful of raw nuts and seeds in your diet daily, especially walnuts, which are good sources of PEOs.
It is important to have the proper ratio of omega-3 and omega-6 in the diet and to let the body make them through using PEOs. We know that Omega-3 fatty acids help reduce inflammation, and most omega-6 fatty acids tend to promote inflammation which, from the outside looking in, isn’t good. However, there MUST be a proper balance between an inflammatory ‘attack’ response and the anti-inflammatory ‘clean-up’. Everything in life is about balance!
Prof. Brian Peskin is a world-leading scientist specializing in parent EFAs — termed PEOs — and their direct relationship to both cancer and cardiovascular disease. He currently spends time advancing the scientific understanding of the role of essential fatty acids in the body’s metabolic pathways, and has developed a means for alleviating cancer’s prime cause, as postulated by Nobel Prize-winner Otto Warburg, M.D., Ph.D., by increasing cellular oxygenation (The Hidden Story of Cancer, www.pinnacle-press.com). From an immune standpoint, there is a fundamental cancer / heart disease connection, whereby the same physiologic solution helps solve both conditions.
Dr. Peskin’s protocol, termed “the Peskin Protocol” will lead to a new understanding of how to better care for patients with both cancer and heart disease. The basis for Peskin’s current work, grounded in physiology — can be found in his seminal work and peer-reviewed medical journal articles. Clinical physicians throughout the world have validated Prof. Peskin’s EFA recommendations. In the most exciting development to date, Dr. Peskin’s theoretical conclusions were recently and completely validated in a physiological experiment by precise instrumentation capable of measuring arterial compliance. This experiment (IOWA experiment) provided the first conclusive clinical proof and validation of Prof. Peskin’s theory. Peskin pharmaceuticals have a patent pending on the medicament that embodies this development.
What is a Parent Essential Oil (PEO)?
There are really only two (2) essential fatty acids, LA (parent omega-6) and ALA (parent omega-3). They MUST come from food. To work properly, they CANNOT be heated, chemically processed, and MUST be organically raised to guarantee full physiologic functionality.
The typical American diet tends to contain 15 – 30 times more omega-6 fatty acids than omega-3 fatty acids – and they are all adulterated! A 1:1 ratio of parent omega-3 : parent omega-6 would be perfect but not very practical if you think you are getting from your current food sources.
The Mediterranean-type diets have a healthier balance between omega-3 and omega-6 fatty acids. I prefer even a more-strict Paleo-type diet for most people, eliminating grains, ‘bad’ carbohydrates, grain-fed meats, and obtaining most of your nutrition from your vegetables, juicing, and stone fruits. Many studies have shown that people who follow this diet are less likely to develop heart disease and have a much greater chance of surviving cancer.
People who follow an Anti-inflammatory diet tend to have higher HDL or “good” cholesterol levels, which help promote heart health. Inuit Eskimos, who get high amounts of omega-3 fatty acids from eating fatty fish (and even blubber), also tend to have increased HDL cholesterol and decreased triglycerides (fats in the blood). Yes, they eat fat and are healthier, have less fat in their blood and liver, and have less cancer! Finally, walnuts (which are rich in alpha linolenic acid or ANA, which converts to omega-3’s in the body) have been reported to lower total cholesterol and triglycerides in people with high cholesterol levels.
Most clinical studies examining parent omega-3: parent omega-6 fatty acid supplements for autoimmune disorders have focused on rheumatoid arthritis (RA), an autoimmune disease that causes inflammation in the joints. A number of small studies have found that it helps reduce symptoms of RA, including joint pain and morning stiffness by reducing the acute inflammation.
Eating foods rich in PEOs seems to reduce the risk of colorectal cancer according to research and observance. For example, Eskimos, who tend to have a high fat diet as described above, but end up eating high amounts of PEOs, have a low rate of colorectal cancer. Animal studies and laboratory studies have found that omega-3 fatty acids prevent worsening of colon cancer as well. Preliminary studies suggest that taking PEOs daily may help slow the progression of colon cancer in people with early stages of the disease. Although not all experts agree, women who eat foods rich in PEOs over many years may be less likely to develop breast cancer.
Population based studies of groups of men suggest that a ‘good’ fat diet including PEOs help prevent the development of prostate cancer. The biggest thing to remember about good oils and cancer is the anti-inflammatory benefits. Remember, rapidly reproducing cells (cancer) give off a large amount of acidic waste that form an inflammatory ‘slime’ layer around the growing mass that protects it and prevents your immune system from killing it. Anything one can do to decrease this ‘slime’ layer will have benefits in allowing your body to kill the cancer cells.
PEOs and Cancer
The his book, “The Hidden Story of Cancer”, Dr. Peskin details the molecular biochemistry of why cancer develops and shows that no ‘genetic cause’ will ever be found to the majority of cancers. Remember that cancer is not a foreign invader, but is rather a primitive defense mechanism for survival in a very unhealthy environment. Medical research understood that cancer comes from within our own bodies, but they viewed our bodies’ cells as being somehow genetically programmed to “turn on themselves.” “This is where they make their mistake: The body is not turning on itself; instead, it is struggling to survive in the only way it can,” write Peskin. Cancer cells survive by making energy using fermentation.
Most cancers are not and have never been genetic in origin. What is correct is that the cancerous tissue is surrounded by unhealthy, oxygen-deprived tissue that has allowed the uncontrolled growth to take place. However, it gets worse. Many tissues are oxygen deprived along with the cancerous ones – it is NOT a local problem, it is a systemic problem. Homer Macapintac, M.D., chair and professor of nuclear medicine at The University of Texas M.D. Anderson Cancer Center for stating this truth: “Breast cancer is not a local problem. It is a systemic [whole body] disease.”
One MAJOR reason that our tissue becomes oxygen deficient and more acidic is simple: by eating adulterated oils and fats from the food processing industry and from your supermarket’s cooking oil section! These adulterated oils have a long shelf-life but have lost their oxygenation ability. They started out containing the functional, vitally needed oxygen-transferring PEOs (Parent Essential Oils), but they were ruined by processing and refining. Your body can’t make them on its own; they MUST come from food. We are giving ourselves cancer by eating common, everyday processed foods! Transfats are only the “tip of the iceberg” of the methods used by food processors to obtain long shelf-life and ruin the oxygenation capability of fats. PEOs work like tiny “magnets” drawing oxygen into all cells, tissues, and vital organs.
Dietary Sources:
Plant and nut oils are the primary dietary source of PEOs. ALA is found in flaxseeds, flaxseed oil, canola (rapeseed) oil, soybeans, soybean oil (BUT do NOT take canola oil or soy products with cancer!!), pumpkin seeds, pumpkin seed oil, purslane, perilla seed oil, walnuts, and walnut oil.
Taking a supplement is really necessary unless you eat a perfect diet. I use ONLY Dr. Peskin’s Protocol now (I was under the same mis-understanding as most other nutritionists regarding fish oil) and ONLY recommend Life System International’s product. Life Systems International Parent Essential Oils (PEOS) are organically produced, cold-pressed seed oils containing “parent” omega 6 and “parent” omega 3. They are infinitely better than fish oil supplements. Fish oils are not as pure or as effective as organic, wildcrafted seed oils and can even be harmful. These PEOS are produced to very specific, high scientific standards. You may order you own PEO supplements at Life Systems International’s website.
I have absolutely NO financial ties to this company!
This was an excerpt from Dr Conners’ book, Stop Fighting Cancer and Start Treating the Cause.
Free Download Buy the Book
Dr. Kevin Conners, D.PSc., FICT, FAARFM
Dr. Conners graduated with his doctorate from Northwestern Health Sciences University in 1986 and has been studying alternative cancer care for over 20 years. He holds AMA Fellowships in Regenerative & Functional Medicine and Integrative Cancer Therapy.
He is the author of numerous books including, Stop Fighting Cancer and Start Treating the Cause, Cancer Can’t Kill You if You’re Already Dead, Help, My Body is Killing Me, Chronic Lyme, 3 Phases of Lyme, 23 Steps to Freedom, and many more you can download for FREE on our books page.
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The Greatest Guide To hair growth vitamins
We’d adore to listen to your opinions relating to hair loss shampoos. We want to hear what you think that and we promise to reply immediately. How to hurry up hair growth? There are several unique hair loss treatment selections you could quicken the hair growth. Additionally you need to consume healthier food and nourish the hair with Unique oils to generate your hair shine. https://twitter.com/steptoremedies/ may also select hair regrowth treatment which can help in hair re-growth. What would take place if you keep an elastic band stretched for hrs? It'll begin to shed the extend. Also, constantly listen to an item’s list of ingredients to make certain that it doesn’t consist of some thing which can lead to an allergic reaction. visit is among the most successful baldness treatment which happens to be non-surgical in character. Stem cells have the innate ability to renew and multiply on their own. On the list of positives of buying a hair-loss shampoo that contains a lot of the significant ingredients in preventing hair loss is individually paying for the components isn’t Price-helpful. A bottle of castor oil costs during the $twenty to $thirty range, for instance. Ordinarily, clients can see it commence Doing work in six to eight months, but it can also lessen sexual intercourse travel, raise breast dimension, and add to erectile dysfunction, As outlined by Merck Manuals. It's also unsafe for pregnant women to touch the crumbly tablet powder. The greatest rationale men reduce hair is on account of follicle DHT-sensitivity, and ketoconazole is proven to overcome this. It is simply too early to state if this is Doing work but interested to listen to what you're thinking that or irrespective of whether I must use another thing. Many thanks I'll checklist them down in no specific get. You can try out a number of depending upon the availability and liking: This condition interferes with the hair growth cycle by creating a follicle to prematurely depart the anagen, or active growth, period and enter the resting, or telogen section. https://www.pinterest.com/healthhomeremedies/steptoremedies/ while in the influenced follicles is lessened or stopped fully. I’m so grateful for stumbling across this article, so thank you, Dormen! It's exceedingly hard to come across articles like this wherever there isn’t an evident kickback in Enjoy, They have a tendency to advocate solutions (.e.g, Pura d’Or) which have been Evidently not ideal for hair loss and thinning. As https://steptoremedies.com/stimulate-hair-growth-permanently/ to the power of all-natural botanicals and herbs, the company even offers a a hundred% cash-back again warranty so there is absolutely no threat to purchasing and trying this hair growth solution. I tried a couple of of People over the list then I started off using mak hair zoe vitamin shampoo and conditioner about a year back and are actually incredibly pleased. I finished loosing hair and seems to grow a little more quickly. Furthermore, it offers a lot of body and leaves no Make up. Truly very good things.
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At the end of this portion I’ll show you why workout routines and massages assistance to stimulate blood stream dramatically and thereby will help reverse (cure) hair loss. Your whole body makes vitamin D by way of immediate contact with the Solar's rays. Very good dietary source s of vitamin D contain fatty fish, cod liver oil, some mushrooms and fortified foods. As SFRP1 induces catagen period Considerably before ordinary, this displays that CsA is an efficient inhibitor with the protein. Trying to find a hair growth shampoo that forestalls dandruff at the same time? Nizoral has created a product which includes the exact benefits you are searhing for. Shop-acquired shampoos consist of various chemical substances and preservatives producing them a nasty choice for Those people with hair loss. https://www.youtube.com/channel/UC-SiXXn3EKKI2t7btdwEplw that happen to be homemade, on the other hand, is often among the finest things you can perform for growing your hair. A surgical way of hair loss treatment, hair transplants are a popular option for a range of people struggling from AGA or other hair loss forms. Irrespective of whether this treatment is ideal for you will rely upon several aspects. As you could see in the diagram below, the hair follicle is provided by blood which permit the strand of hair to grow. Find out how using a vitamin D deficiency can contribute to hair loss and what you are able to do to keep up healthy vitamin D stages in your body. Among the to start with studies done over the plant relating to hair growth was completed in 1998. Members got both a placebo, a noticed palmetto lotion, a saw palmetto oral supplement, or a mix of the two noticed palmetto substances. At the end of the fifty-week study, these have been the outcome: However, there are actually countless items in existence that guarantee unrealistic final results, only to go away you let down. When studying https://www.youtube.com/watch?v=cHyMGYtWoQ4 for hair loss, here are a few elements to bear in mind. It’s clear which the listing of microorganisms killing modern-day inventions is very long. It’s tough to do just about anything devoid of managing into anything intended to get rid of bacteria in one form or A further. Obviously taking in extra alkaline foods and less acidic ones can help to change the human body back into it’s natural alkaline state and guard the scalp from excess DHT. These statements haven't been evaluated with the FDA & usually are not intended to address or cure any sickness. Talk to a health care Qualified prior to making any conclusions. Individuals have been declaring a ‘cure for hair loss’ is going to be accessible in ‘5 calendar year’s time’ for so long as anybody can recall.
hair fall solution No Further a Mystery
Finasteride has limitations though, like the requirement of daily treatment, a Restrict to the amount of damaged hair follicles it may revive, and that it may lose its success time beyond regulation for a number of people. https://www.youtube.com/watch?v=SB0QLruqRrQ can offer the client we an exceptionally natural hunting head of hair. A latest technological innovation is robotic assisted hair transplantation which enable the surgeon be a lot more specific and keep scalp scarring small. The limitations? Every person goes via bouts of enhanced sinus strain on occasion, some a lot more than the others. Your paranasal sinus... Realizing for https://www.facebook.com/steptoremedies/ at an early age whether a person are going to be predisposed to shedding their hair can make a big difference. This may support that person be capable to prepare, price range, and analysis their alternatives ahead of their hair even begins thinning. A number of it's going to grow back but you'll need to wait on it maybe a few months and it could grow back again weak and liable to breakage. The neatest thing you could potentially do is consume healthier and nourish your scalp -- and see a health care provider for advice. Well-liked hair growth products and natural cures for hair loss Hair loss normally occurs in the event the cycle of hair growth and hair shedding is disrupted. On this shampoo, we include two a lot more factors: pure honey and castile soap. Honey is a great moisturiser and provides luster to dull hair. When castile cleaning soap is really a natural cleaning soap made from plant oils and is also free of nasty preservatives, colours and perfumes. I accustomed to have truly thick curly hair nonetheless it hasn't liked growing Substantially… Now it is de facto thin, wonderful and greying and continue to curly nevertheless it retains snapping off and continue to not finding any more.. This kind of alopecia is frequently attributed to genetic predisposition and family members record. Androgenic alopecia seems in equally Gentlemen and women. https://www.youtube.com/watch?v=NMrck8zLy8A in Guys is frequently faster, previously onset, and more considerable. Although https://www.wikihow.com/Reduce-Hair-Loss argue that a essential component – ketoconazole – is missing, The truth is the item however will work. This shampoo hydrates, circumstances, and helps to grow hair and lower loss without having extra substances, which makes it absolutely value a consider. Besan also consists of amazing quantities of antioxidants which shield the hair from damaging effects of absolutely free radicals. Initially, create a cup of inexperienced tea with one particular tea bag (or 1 teaspoon of unfastened tea). Pour a cup of hot water on eco-friendly tea bag and let it steep for thirty minutes or until finally amazing. (use filtered or distill water to make this tea, nonetheless it’s not important). I had a foul practice of pulling out my hair Hence the white factor would arrive out (root/foundation), and now I have a bald location. Will it ever grow back again? Essentially the most substantial form is alopecia totalis, where all the scalp goes bald. It is vital to emphasize that individuals who definitely have localized hair loss typically You should not go on to lose hair everywhere in the scalp. Alopecia areata can have an impact on hair on other areas of the human body, too (one example is, the beard or eyebrows).
Details, Fiction and hair fall treatment
It are not able to fully reverse hair loss but can Enhance hair growth and repair service weakened strands. The method for this shampoo incorporates numerous established natural components and vitamins that market hair growth. It can nourish hair and decrease signs or symptoms like DHT blocking that may result in hair loss. Most hair loss isn't associated with systemic or inside disease, nor is very poor eating plan a Repeated component. Hair could just skinny because of predetermined genetic factors and the general getting old course of action. But in almost any scenario, I’m no expert and I don’t desire to set shampoo that’s long gone bad on my now Just about bald head. Could you inform me tips on how to check for lousy EGG shampoo please? It's possible I could e-mail you a picture or one thing If you're able to give me your e-mail? I had a very good treatment listen to for far better hair growth. Its extremely natural and fastest method to grow your hair Once more ...Browse Less Is there a correlation involving hair loss and strain? Both of those emotional and Bodily stress (like a significant disease or recovery from operation) are actually connected with hair loss. Hair-fiber powders: Colored, powdery fiber sprinkles are commercially available and may work to camouflage balding spots. visit colored sprinkles have Exclusive Attributes that aid them attach to hair and give a fuller visual appeal. Toppik is 1 company of these products and solutions and are available on the internet. The egg can be naturally pH balanced. This high-quality is so essential if you would like keep your scalp healthy and no cost from fungus and various microbes. The hair follicle can be a tunnel-like phase from the epidermis that extends down into the dermis. The composition is made up of various layers that each one have different functions. At The bottom from the follicle will be the papilla, which has capillaries, or small blood vessels that nourish the cells. Involutional alopecia - is really a natural approach, whereby, hair thinning takes place with age. With ageing, most of the hair follicles go in to the dormant or resting section, whilst the size of the rest of the hairs gradually develop into shorter and Due to this fact, the hair amount becomes thinner. Viewers Comments 28 Share Your Tale You will discover number of scientifically tested and FDA-authorised treatments for hair loss. You will discover 1000s of unproven claims and products and solutions to assist with hair regrowth. A lot of conditioners, shampoos, vitamins, and also other products and solutions declare to assist hair grow in some unspecified way. Nioxin is a well known manufacturer of shampoo for hair loss, but there's no powerful proof exhibiting it is any simpler than normal shampoos. The extent of thyroid hormones might support to diagnose hypothyroidism or hyperthyroidism. The exam may additionally point to other disorders of situations from the thyroid gland. The biotin, the leading component for hair regrowth On this shampoo, performs slowly but surely. You'll have to use this shampoo for at least six months prior to deciding to can observe the outcome. It will require that very long since the formula strengthens hair strands from the root. Vitamin C is a robust antioxidant that assists defend from the oxidative stress a result of totally free radicals (six). Are you currently accomplishing proper by your skin? Go ahead and take Skin and Make-up Quiz to find out how to take advantage of within your elegance regimen.
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.coconut and castor oil in very first leaving on for 30 minutes..my hair is previous my bra line…it will require about 6 months ..but it really does operate..I also use coconut oil less than my eyes Every now and then…no wrinkles…I smoke…drink and take in junk food stuff in addition look at my grandkids element time…take pleasure in existence Even though more expensive than other hair loss shampoos, when you’re in search of final results and don’t care about conserving revenue as you don’t choose to go bald, Ultrax Labs is the greatest shampoo on the market. I have menopause now my hair is thining and have bald sopts any recommendations for a house cure thanks. The evaluations of Other individuals may also be important as was the nutritional supplement’s rate. As generally, we try to look for things that healthy any man’s spending plan. For now, just realize that there are many hair growth supplements, tablets, and vitamins on the market. We’ll contact on the most effective kinds in the following paragraphs, but be wary of inferior items that do absolutely nothing greater than overload you with certain vitamins and minerals without the need of accomplishing a matter for hair growth. Pregnancy is one illustration of the kind of physical worry that could potentially cause hair loss (that and hormones). Pregnancy-linked hair loss is seen much more normally immediately after your child continues to be sent rather then in fact through pregnancy. “Giving delivery is rather traumatic,” suggests Dr. Glashofer. How to proceed: Besides avoiding these styles and treatments, the American Academy of Dermatology suggests using conditioner immediately after every shampoo, letting your hair air dry, restricting the amount of time the curling iron is available in contact with your hair and utilizing warmth-pushed goods not more than once a week. For anyone who is balding or see thinning hair, then finding the best hair loss shampoo is significant for regrowth. While there are several causes for guys’s hair loss, like genetics, pressure, vitamin deficiencies and excess styling, there are numerous great hair growth shampoos, conditioners, and products which can stop loss and even enable grow hair back. Quite possibly the most permanent solution for all those who have lost or are losing their hair is hair transplants. Follicles are harvested from the back again of the head and seeded into bald spots. Tactics have vastly improved and now not do these appear to be faux “plugs”. Ketoconazole stops your follicles from discomfort and inflammation, which subsequently stops hair thinning and loss. With one% Ketoconazole (or two% with a prescription), this product has adequate of the critical ingredient to get rid of the fungi accountable for resulting in dandruff. And vitamin C is a strong antioxidant, and it can help to get rid of hair damaging totally free radicals that happen to be produced Commonly within our bodies. But as we age, their quantity retains on escalating. Sustain healthier hair by next a superb hair treatment regimen and employing hair products that are well suited for your hair type. Plus, protect https://www.wikihow.com/Take-Care-of-Your-Hair from Sunshine problems and prevent the use of heat styling merchandise. They aren’t escalating your full hair depend, just shifting around the hair you might have remaining. Moreover, it doesn’t prevent foreseeable future hair loss and at times supplemental transplants are necessary. Aim for 5-6 portions of fruits and vegetables daily. You don’t should consume exotic, high priced kinds. Eat extra variety and try to eat what grows locally and what variations seasonally – since they incorporate optimum goodness and so are ideal for your hair, health and pores and skin.
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Liver Damage Is a Growing Epidemic Dr. Mercola By Dr. Mercola According to the American Cancer Society,1 liver cancer affects an estimated 41,000 Americans each year, and prevalence is rising.2 Between 2000 and 2016, the annual death toll from liver cancer rose by 43 percent for men and 40 percent for women,3 killing more than 11,000 people in 2016.4 The five-year survival rate for localized liver cancer is 31 percent, while regional cancer that has spread to other organs and distant liver cancer have survival rates of just 11 percent and 3 percent respectively. Globally, the liver cancer hepatocellular carcinoma (HCC) is the second leading cause of cancer death due to the high prevalence and difficulty of treatment. Researchers warn that by 2030, the global rate of liver cancer will double, affecting upward of 1.2 million.5 Other liver-related diseases such as cirrhosis and nonalcoholic fatty liver disease (NAFLD) are also becoming more prevalent. Between 2001 and 2013, the number of diagnosed cirrhosis cases nearly doubled,6 and deaths from cirrhosis increased by 65 percent between 1999 and 2016.7 The greatest increase (10.5 percent) was among those between the ages of 25 and 34, where alcoholic cirrhosis has become rampant.8,9 Excess Alcohol Consumption Is Driving Rising Rates of Liver Damage According to researchers, the rise in cirrhosis mortality is entirely driven by excess alcohol consumption by young adults. While, historically, alcohol-related liver cirrhosis has been regarded as a condition that develops after two or three decades of heavy drinking, these newer statistics reveal it doesn't have to take that long at all, as it's now occurring in (and killing) 20- and 30-year-olds. In the 25 to 34 age group, death from alcohol-related liver disease nearly tripled between 1999 and 2016. This increase parallels statistics10 showing a rise in binge drinking between 2002 and 2012. It also correlates with the global financial crisis in 2008, after which more people began dying from cirrhosis. Researchers believe financial worries and unemployment may have been significant contributing factors, causing more people to drink more heavily. Cirrhosis (irreversible scarring of your liver) can also be caused by obesity, NAFLD and hepatitis, and can in turn lead to fatal liver failure and/or liver cancer. Men are particularly at risk, in large part because they're five times more likely to develop NAFLD than women. Lifestyle factors such as diet, exercise, weight, smoking and alcohol consumption also play important roles in exacerbating (as well as reducing) your chances of developing some form of liver disease. People at increased risk also include those who have an autoimmune disease, chronic liver inflammation, and those whose livers have been damaged due to bouts of hepatitis B or C. The good news is that alcohol-related liver cirrhosis can be reversed if caught early enough — and provided you quit drinking. Excess Sugar Consumption Drives Rising NAFLD Rates While alcohol-related cirrhosis is driving up mortality rates, rising prevalence of NAFLD is contributing to the overall burden of liver-related diseases. In the case of NAFLD, the fatty liver occurs in the absence of significant alcohol consumption, and is driven instead by excess sugar, which is why this condition is now found even in young children. NAFLD often has no symptoms, although it may cause fatigue, jaundice, swelling in the legs and abdomen, mental confusion and more. If left untreated, it can cause your liver to swell, called nonalcoholic steatohepatitis (NASH), and can lead to liver cancer or liver failure. As with alcohol-related cirrhosis, however, NAFLD can be reversed in its early stages by eating right and exercising. Most importantly, you need to eliminate processed fructose and other added sugars from your diet. Fructose actually affects your liver in ways that are very similar to alcohol. Unlike glucose, which can be used by virtually every cell in your body, fructose can only be metabolized by your liver, as your liver is the only organ that has the transporter for it. Since all fructose gets shuttled to your liver, if you consume high amounts of it, fructose ends up taxing and damaging your liver in the same way alcohol and other toxins do. The way your liver metabolizes fructose is also very similar to that of alcohol,11 as both serve as substrates for converting carbohydrates into fat, which promotes insulin resistance, dyslipidemia (abnormal fat levels in the bloodstream) and fatty liver. Fructose also undergoes the Maillard reaction with proteins, leading to the formation of superoxide free radicals that can result in liver inflammation similar to acetaldehyde, an intermediary metabolite of ethanol. According to Dr. Robert Lustig, a neuroendocrinologist in the division of endocrinology at the University of California, fructose is a "chronic, dose-dependent liver toxin." Excess Glucose is Converted to Fructose and Decimates Your NAD+ I recently read an excellent review12 on NAD that helped me understand the basic biochemistry far better, and it makes perfect sense. It is not only eating excess fructose in processed foods that is the problem, but excess glucose is ultimately converted to fructose by your body in an effort to metabolize glucose for energy. Let me explain it to you. When your body is exposed to chronic glucose excess, the first enzyme in breaking down glucose is hexokinase, and this enzyme becomes saturated and can't break down any more glucose. Once this occurs, glucose will then be metabolized through the polyol pathway, in which glucose is metabolized to sorbitol by aldose reductase, and sorbitol is subsequently metabolized to fructose by sorbitol dehydrogenase (see figure below). It is estimated when you are healthy, only about 3 percent of glucose goes through the pathway below, but at least 30 percent of glucose flows through this pathway in chronic hyperglycemia,13 creating a vicious cycle of excess fructose. This metabolic catastrophe is the net redox result of the trading of one molecule of NADPH for one molecule of NADH. This is precisely what you don't want to happen, as NADPH is used as a reductive reservoir for your antioxidants and is necessary to make your steroid hormones and fats. When you have low levels you are in deep trouble. Complicating it further, you increase NADH and worsen your NAD+/NADH ratio. As fuel supply outstrips metabolic demand, mitochondrial and cytoplasmic NAD/NADH ratios fall. The ensuing mitochondrial membrane hyperpolarization perpetuates electron leakage and excessive oxidative stress. Fortunately, the good news is that there is a simple inexpensive solution that should radically improve this metabolic catastrophe. The first, of course, is to clean up your diet as we have previously discussed many times, so your body can burn fat for fuel. But you can also take NAD precursors like simple nontimed-release niacin. That should help increase the NAD+/NADH ratio and NADPH levels. As noted in one recent paper,14 "Oral administration of nicotinamide riboside, a natural NAD+ precursor, completely corrected these NAFLD phenotypes induced by NAD+ deficiency." I would start at 25 to 50 milligrams a few times a day, as any dose higher will likely cause a harmless but relatively annoying flushing sensation. It would also be helpful to reduce your exposure to electromagnetic fields, as that also consumes NAD+ through PARP hyperactivation and will worsen the metabolic condition. Low-Level Chemical Exposures Linked to Liver Damage While there's no data on this, it's possible that alcohol-induced cirrhosis is now occurring sooner as a result of liver damage caused by chemical exposures. Researchers have shown that even small amounts of chemicals from food, pharmaceuticals and personal care products can in fact cause liver damage. One such experiment15 was designed to evaluate the effects of chemical combinations at low doses from environmental sources such as food, pharmaceuticals and personal care products.16 Using four groups of Sprague-Dawley rats, the researchers administered a mix of chemicals found in everyday products in their drinking water at varying doses for a period of six months. The control group received chemical-free water. Of the three treatment groups, the low-dose group received 25 percent of the European Union (EU) acceptable daily intake for the chemicals in question, the medium dose group received exactly the acceptable daily intake defined by the EU, while the high-dose group received five times the acceptable daily intake.17 After six months, body weight and biochemistry markers were evaluated, revealing the animal's weight increased more than 10 percent in all male groups, compared to controls.18 Modest increases were found in females given medium and high doses of the chemicals. They also discovered adverse liver effects — especially at the low-dose level and primarily in the males. Overall, the results suggest exposure to low doses may induce liver damage as a result of the combination of different toxic mechanisms, and supports previous research showing that chemical cocktails, even at low levels,19 can damage liver function20 and trigger cancer.21 Roundup Damages Liver at Ultra-Low Doses Roundup, the most heavily-used weed killer in the world, has also been linked to liver damage. Disturbingly, urine levels of glyphosate have skyrocketed in the past couple of decades, suggesting widespread, chronic exposure, most likely from food. Between 1993 and 2016, levels of the chemical in human urine increased 1,200 percent.22 Recent food testing also reveals that most foods sold in the U.S. are contaminated with glyphosate. This is of significant concern, as research suggests Roundup can cause significant liver damage even at ultralow doses. The study,23 published in the journal Scientific Reports, looked at the effects of glyphosate exposures of 4 nanograms per kilogram of body weight per day, which is 75,000 and 437,500 times below EU and U.S. permitted levels, respectively. After a two-year period, female rats showed signs of liver damage, specifically NAFLD and progression to nonalcoholic steatohepatosis (NASH). Study author Michael Antoniou, Ph.D., told Sustainable Pulse:24 "The findings of our study are very worrying as they demonstrate for the first time a causative link between an environmentally relevant level of Roundup consumption over the long-term and a serious disease — namely nonalcoholic fatty liver disease. Our results also suggest that regulators should reconsider the safety evaluation of glyphosate-based herbicides." Milk Thistle Helps Prevent Liver Damage Milk thistle is an herb that has been used for thousands of years to support liver, kidney and gallbladder health. In modern times, silymarin has been used to treat alcoholic liver disease, acute and chronic viral hepatitis and toxin-induced liver diseases. The active ingredient, a flavonoid called silymarin, is thought to be responsible for the beneficial effects attributed to milk thistle, including liver protection, antioxidant, antiviral and anti-inflammatory properties. In your liver, silymarin works as an antifibrotic, thereby preventing tissue scarring, and blocks toxins by inhibiting the binding of toxins to liver cell membrane receptors. Silymarin also protects your liver and promotes healthy liver function by: Suppressing cellular inflammation25 Inhibiting the mammalian target of rapamycin (mTOR), a pathway that, when overactivated, increases your risk of cancer26 Activating AMPK (activated AMP-activated protein kinase),27 an enzyme inside your cells. AMPK is sometimes referred to as a "metabolic master switch," as it plays an important role in regulating metabolism and energy homeostasis.28 AMPK produces many of the same benefits as you would get from exercise and weight loss, both of which benefit your liver health Reducing liver injury caused by a number of drugs and environmental toxins, including acetaminophen, chemotherapy, psychotropic drugs and alcohol Increasing glutathione, a powerful antioxidant that plays a role in the detoxification of heavy metals and other harmful substances N-acetylcysteine Supplement Supports Your Liver Health Another powerful liver protectant is N-acetylcysteine (NAC), a precursor needed for glutathione biosynthesis. In fact, research suggests NAC may be a better alternative for supporting liver health in those with hepatitis C and other chronic liver diseases than the antioxidant resveratrol.29 Alcohol and acetaminophen are two common compounds metabolized through the liver that are associated with liver damage. NAC supplementation has been effective in minimizing damage associated with alcohol consumption when taken prior to alcohol ingestion.30 NAC is also used as an antidote for acetaminophen toxicity, which causes liver damage by depleting glutathione.31 Research published in Hepatitis Monthly32 has also shown NAC supplementation helps improve liver function in patients with NASH. Folate Deficiency Worsens Severity of NASH Increasing your intake of folate can also help protect your liver function. In a study33 involving 83 patients with NASH, researchers found levels of folate and vitamin B12 were inversely related to the development of fibrosis or the formation of scar tissue. Past research has identified an association between low levels of vitamins and chronic liver disease, but this is the first to find an association between folate and vitamin B12 level to NASH severity. Studies have also shown folate deficiency can increase your risk for liver cancer.34,35 In one, which involved hepatitis B-positive patients (who are at higher risk for liver damage), higher folate levels were associated with a 67 percent lower risk of liver cancer.36 According to the authors, increased folate in humans appear to be inversely associated with the development of liver damage and hepatocarcinoma, and that folate can offer the liver some degree of protection against damage. Folate may also mitigate against pesticide-related damage, including autism. Your body stores approximately 10 to 30 milligrams of folate at a time, nearly 50 percent of which is in your liver. Folate is the natural form of vitamin B9 found in foods and once referred to as folacin. The word was derived from the Latin "folium," meaning leaf. Green leafy vegetables such as spinach are abundant sources of folate, as are asparagus, broccoli, Brussels sprouts and avocados.37 Broccoli is perhaps ideal, as research38 has confirmed it helps protect against NAFLD. Avoid folic acid supplements however. While readily absorbed, this synthetic form is not converted in the intestines like folate is. Instead, it is converted in your liver. This means folic acid can reach saturation quicker, which may result in overexposure if you're taking supplements. Coffee May Cut Risk of Liver Cancer Last but not least, if you're a coffee drinker, you may be relieved to find out that coffee appears to have a protective effect against HCC, a serious form of liver cancer and the second-most prevalent cause of death from cancer in the world. Drinking a single cup of coffee every day cuts your risk of HCC by one-fifth.39,40 If you drink more than that in a day, your risk for liver cancer is even lower. Two cups of coffee a day cut the risk by 35 percent, and five cups cut the risk in half. That said, excessive coffee consumption can have other adverse effects. As noted by lead author Dr. Oliver Kennedy from the U.K.'s University of Southampton:41 "We're not suggesting that everyone should start drinking five cups of coffee a day though. There needs to be more investigation into the potential harms of high coffee-caffeine intake, and there is evidence it should be avoided in certain groups, such as pregnant women." To optimize your health benefits from coffee, make sure it's organic, and drink it black, without milk or sugar. A far better alternative would be "bulletproof coffee," where you add butter or MCT oil to the coffee instead of sweeteners. To learn more about how you can make coffee a healthy part of your day, see "Coffee Leads to Longer Life."
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Why Coconut Oil, or Any Saturated Fat, Cannot Raise Cholesterol Levels (LDL levels)
Comments by Brian Shilhavy Editor, Health Impact News
Scottish medical doctor, Malcolm Kendrick, has just written a brilliant expose on his blog explaining, scientifically, why it is impossible for saturated fats to raise LDL cholesterol levels.
As I have written many times over the years, this is the kind of information that can save your life and help you make wise dietary choices, but it is information that the U.S. government, Big Pharma, and the corporate-sponsored “mainstream” media cannot afford to publish.
Because to do so would be to admit guilt in one of the biggest medical scams of all time: the lipid theory of heart disease.
This theory, which has been proven scientifically to be false, has been an economic success for cholesterol-lowering statin medical drugs, the most profitable class of medical drugs all time. This theory also promotes the low-fat diet which encourages consumption of carbohydrates from U.S. subsidized crops, as well as polyunsaturated oil, also derived from U.S. subsidized crops.
This theory of heart disease, which condemns cholesterol and saturated fat, has probably been responsible for many millions of people's early deaths and the life-long suffering of autoimmune diseases for an entire generation.
Why saturated fat cannot raise cholesterol levels (LDL levels)
by Dr. Malcolm Kendrick DrMalcolmKendrick.org
“Explanations exist; they have existed for all time; there is always a well-known solution to every human problem - neat, plausible, and wrong.” H.L. Mencken.
Of all the flaws of the human mind, the number one must be the overwhelming desire to find simple, easy to understand answers – to everything. I think this is why my favourite film of all time is Twelve Angry Men. It was a stage play first.
A black youth is accused of killing his father. The evidence that is presented by the prosecution seems utterly overwhelming. A unique knife is used for the murder, one that the youth was known to carry. He was seen leaving the apartment after shouting 'I'll kill you' and suchlike. Most importantly, however, he was a young black youth, and young black youths are widely considered to be the sort of person who do such things.
In the film, prejudice presses down heavily on most of the jurors. Some of them, it is hinted, would have found him guilty no matter if there had been any evidence, or not. Here we have all the worst aspects of human decision making on show. Confirmation bias, prejudice, gathering together only the evidence that supports a case, the desire to 'get on with it' and not hang about listening to people who just want to make things complicated.
In my mind, for many years, I have changed 'black youth', into the word 'cholesterol' as I watch the 'heart disease jurors' in action. A suspect was found, fitted up, put on trial and found guilty by people who were just desperate to get on with it. At the very first congressional meetings on dietary guidelines, any attempts to wait until there was sufficient evidence, were railroaded.
'When the US government introduced “Dietary Goals for the United States”, they did not have unanimous support. The guidelines, which urged the public to cut saturated fat from their diet, were challenged by a number of scientists in a Congressional hearing. The findings were not based on sufficient evidence, they argued.
They were ignored. Dr. Robert Olson recounts an exchange he had with Senator George McGovern, in which he said: “I plead in my report and will plead again orally here for more research on the problem before we make announcements to the American public.” McGovern replied: “Senators don't have the luxury that the research scientist does of waiting until every last shred of evidence is in.'
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Senator McGovern might as well have said. 'Listen son, we know that saturated fat raises cholesterol and causes heart disease, we don't need any damned evidence.' Of course, they didn't have any evidence at all. None. But they still managed to find saturated fat and cholesterol guilty. Some people would call this proper leadership. Make a decision and go with it.
I would call it monumental stupidity.
As you can see I am stepping back in this blog to look at saturated fat – again. Because I am going to share some thinking with you, which I have not really shared before. Some of you will know that I am a 'first principles' kind of guy. I take very little at face value, and I am certainly highly critical of accepted wisdom: I usually translate it, in my mind, into accepted stupidity.
So, I am going to try and explain to you that saturated fat cannot raise blood cholesterol levels. By which I mean low density lipoprotein levels (LDLs) as this is the substance which someone or another ended up calling 'bad' cholesterol. It is the lipoprotein that is thought to cause CVD.
However, LDL is not cholesterol, it never was. We do not have a blood cholesterol level – but we are seemingly stuck with this hopelessly inaccurate terminology for all time.
Anyway, the idea that saturated fat raised cholesterol was driven by Ancel Keys in the late nineteen forties. The first point to make here is that, when Keys first started his anti-fat crusade, no-one knew that there was such a thing as LDL. You took a blood test, gathered together all the lipoproteins you could find (good, bad, and indifferent) and measured them all. Quite what they were measuring is a good question.
Despite this rather important gap in his knowledge, Ancel Keys was able to create an equation to exactly predict the effect of saturated and polyunsaturated fatty acids in the diet on serum cholesterol levels.
Change in serum cholesterol concentration (mmol/l) = 0.031(2Dsf − Dpuf) + 1.5√Dch
[Where Dsf is the change in percentage of dietary energy from saturated fats, Dpuf is the change in percentage of dietary energy from polyunsaturated fats, and Dch is the change in intake of dietary cholesterol].
This became the accepted wisdom. You could believe, given the apparent precision of this equation, that he did some proper research to prove it was true. Frankly, it seems bloody unlikely, as the equation contains the 'change in dietary cholesterol' as a key factor in raised blood cholesterol levels. It is now accepted that cholesterol in the diet has no significant impact on blood cholesterol levels. Keys even knew this himself.
To quote him from a paper in 1956:
'In the adult man the serum cholesterol level is essentially independent of the cholesterol intake over the whole range of human diets.'
In 1997 Keys wrote this:
“There's no connection whatsoever between cholesterol in food and cholesterol in blood. And we've known that all along. Cholesterol in the diet doesn't matter at all unless you happen to be a chicken or a rabbit.” Ancel Keys, Ph.D., professor emeritus at the University of Minnesota 1997.
More recently, the fact that cholesterol in the diet has no impact on 'cholesterol levels' or CVD was reaffirmed. In 2015, the Dietary Guidelines Advisory Committee in the US, having reviewed all the evidence made this statement:
“Cholesterol is not considered a nutrient of concern for overconsumption.” 2
This was even supported by the likes of Walter Willet and Steven Nissen:
'Nutrition experts like Dr. Walter C. Willett, chair of the Department of Nutrition at Harvard School of Public Health, called the plan a reasonable move. Dr. Steven Nissen, chair of cardiovascular medicine at the Cleveland Clinic, told USA Today “It's the right decision. We got the dietary guidelines wrong.'3
Anyway, Keys had started out with a hypothesis that cholesterol in the diet raised cholesterol levels in the blood but discarded it after feeding eggs to volunteers (eggs contain more cholesterol than any other food) and finding that their cholesterol level remained stubbornly unchanged.
Undaunted, he did what no scientist should ever do. He simply changed the hypothesis. The nutrient of concern was no longer cholesterol, it was saturated fat. So, what is it about saturated fat that can raise LDL? I wanted to know the exact, proven, mechanism.
We start with the certain knowledge that the body is exceptionally good at keeping all substances in the blood under strict control. If the level of something rises too high, mechanisms are triggered to bring them back under down, and vice-versa. The entire system is known as homeostasis.
Thus, if saturated fat intake really does cause LDL levels to reach damaging levels, it must be overcoming homeostasis, and breaking metabolic and physiological systems. How does it do this?
To try to answer this question we should look at what happens to saturated fat when we eat it. The first step is that it binds to bile salts in the bowel. Bile salts are a form of mildly adapted cholesterol, synthesized in the liver and released from the gall bladder. Without bile, fat cannot be absorbed well, if at all, and simply passes through the guts and out the other end.
The absorbed saturated fat is then packed into a very large lipoprotein (known as a chylomicron). Once a chylomicron is formed it travels up a special tube, called the thoracic duct, and is released directly into the blood stream. It does not, and this is important, pass through the liver.
Chylomicrons then travel around the body and are stripped of their fat, shrinking down until they become about the size of an LDL. At which point they are called chylomicron remnants. These are absorbed back into the liver – using LDL receptors – and are then broken down into their constituent parts
Therefore, a small amount of fat that you eat will end up in the liver. However, the vast, vast, majority will go straight from the guts to fat cells (adipose tissue). Whereupon they are stored away for later use.
In fact, this is the fate of all types of fat: saturated, polyunsaturated, or monounsaturated. There is nothing unique about saturated fat in the way that it is absorbed and transported around the body. Anyway, as you may have noticed, none of this has anything to do with LDL whatsoever. Nothing. Ergo the consumption of saturated fat, or any fat, can have no direct impact on LDL levels.
I suppose the next question to ask is simple. Where does LDL come from? LDL is created when VLDLs (very low-density lipoproteins) shrink down in size. VLDLs are the type of lipoproteins that are synthesized in the liver, then released into the bloodstream. They contain fat and cholesterol and, as they travel around the body, they lose fat and become smaller and smaller, until they become an LDL -which contains proportionately more cholesterol.
Almost all LDL molecules are removed from the circulation by LDL receptors in the liver. They are then broken down and the contents used again. Some LDL continues to circulate in the blood, and cells that need more cholesterol synthesize an LDL receptor to bind to LDL molecules and bring the entire LDL/LDL receptor complex into the cells.
Just to re-cap. Saturated fat (any fat) is absorbed from the gut and packed into chylomicrons. These travel around the body, losing fat, and shrink down to a chylomicron remnant – which is then absorbed by the liver. There is no connection between chylomicrons and LDL.
Instead LDL comes from VLDL. VLDLs are made in the liver, they contain fat and cholesterol. VLDLs leave the liver, travel around the body and lose fat, shrinking down to become an LDL.
As the only source of LDL is VLDL, this leads to the next obvious question. What makes VLDL levels rise? Well, it sure as hell isn't fat in the diet. What causes VLDL levels to rise is eating carbohydrates. The next quote is a bit jargon heavy but worth including.
'De novo lipogenesis is the biological process by which the precursors of acetyl-CoA are synthesized into fatty acids [fats]. In human subjects consuming diets higher in fat (> 30 % energy), lipogenesis is down regulated and extremely low; typically This percentage will increase when dietary fat is reduced and replaced by carbohydrate.'4
To simplify this as much as possible. If you eat more carbohydrates than your body needs, or can store, the liver converts the excess (primarily fructose and glucose) into fat in the liver. This process is called de novo lipogenesis (DNL) The fats that are synthesized are saturated fats, and only saturated fats. Once synthesized they are then packed into VLDLs and sent out of the liver.
In short, if you eat fat, the VLDL level falls. If you eat carbohydrates the VLDL level rises. Which is pretty much what you would expect to see.
Moving the discussion on, as VLDLs are the only source of LDL. you now have a conundrum to solve. How can you connect saturated fat intake to a rise in LDL levels, when saturated fat consumption reduces VLDL synthesis? What is the mechanism? The mechanism does not exist!
You could counter by saying, what of the many studies that have shown a fall in LDL when saturated fats are replaced by polyunsaturated fats? Well, this seems to have been shown often enough for me to believe it may even be true.
The explanation for this finding is most likely the fact that, in these studies, saturated fats were replaced by polyunsaturated fats, from plant oils. Plant oils contains stanols (the plant equivalent of cholesterol).
Stanols are known to lower LDL levels, see under Benecol and other suchlike 'low fat' spreads. Because stanols compete with cholesterol for absorption there is an impact on the 'measured' LDL levels. What this means, in turn, is that the studies that demonstrate a lower LDL, with a reduction in saturated fat consumption, fall foul of the two variables problem.
Namely, if you change two variables in an experiment at the same time, you cannot say which of the variables was responsible for the effect you have seen. Was it the reduction in saturated fats, or the increase in plant stanols, that lowers LDL?
This is all tacitly accepted in this Medscape article – again heavy on jargon: 'Saturated Fat and Coronary Artery Disease (CAD): It's Complicated.'
'In a meta-analysis of over 60 trials, higher intakes of saturated fat were associated with increases in both LDL-C and high-density lipoprotein cholesterol (HDL-C) and decreases in triglyceride levels [VLDL}, for a net neutral effect on the ratio of total cholesterol to HDL cholesterol.
Although saturated fats increase LDL-C, they reduce the LDL particle number. Total LDL particle number quantifies the concentration of LDL particles in various lipid subfractions and is considered a stronger indicator of CV risk than traditional lipoprotein measures.
As for stearic acid, the allegedly non-cholesterol-raising fat, while it appears to lower LDL-C relative to other SFAs, one analysis concluded that it raised LDL-C, lowered HDL-C, and increased the ratio of total to HDL cholesterol in comparison with unsaturated fatty acids. And this is one of the confounders of much nutrition research-observations about a given nutrient are highly dependent on what you compare it to.'5
Which is a long-winded way of saying that everything we have been told about saturated fat, its impact on LDL, and its impact on CVD is – frankly – complete bollocks. And if it is complete bollocks, the Keys equation – which has driven all research in this area for seventy years – is also bollocks.
In truth, all possible combinations of LDL going up, down, and staying the same have been found in dietary studies. But I would like to focus on the most recent study. It formed the basis of an episode of a programme called 'Trust me I'm a doctor', on the BBC. Researchers studied the impact of different types of saturated fat on LDL and HDL levels.
For the experiment, the team recruited nearly one hundred volunteers, all aged over fifty. They were split into three groups and every day for four weeks each ate fifty grams of coconut oil (about two tablespoons), or fifty grams of olive oil – an unsaturated fat already known to lower bad LDL cholesterol – of fifty grams of butter.
This amount of coconut oil contains more than forty grams of saturated fat, twice the maximum recommended daily amount for women, according to Public Health England, but is the level previous research has revealed is necessary to show measurable changes in blood cholesterol over a four-week period.
Before the experiment, all the volunteers had their bad LDL and good HDL cholesterol measured, as well as their height, waist, blood pressure, weight and body fat percentage. Four weeks later, these tests were repeated.
The group who ate butter saw their bad LDL levels rise by about ten per cent, as expected. But the olive oil and coconut oil saw no rise in bad LDL – despite coconut oil having more saturated fat than butter.'
Even more surprisingly, while butter and olive oil both raised good HDL cholesterol by five per cent, coconut oil raised it by a staggering fifteen percent, meaning that it seemed to have a more positive effect on cholesterol related health than olive oil.' 6
It is worth pointing out that this was the largest study of the kind ever to have been done. This may surprise you, but in many nutritional studies the number of subjects is often in single digits. In case you are thinking we can simply ignore a study done by the BBC, it was carried out to high standards, and has since been published in the BMJ. Equally I can see no reason why the BBC would have any desire to bias the conclusions in any direction.7
What they found was that coconut oil, containing the highest percentage of saturated fat, had absolutely no impact on LDL. But it did raise HDL (so-called 'good' cholesterol) by 15%. Which is no surprise. If VLDL goes down, HDL goes up. And in this experiment they kept everything else the same, but just added saturated fat. A single variable.
Anyway, the thing that interests me most, and the reason for writing this particular blog is that I have come to the realisation that the best way to find the answer to a scientific question is to immerse yourself in the science. I would like to believe the published research, because it would be lovely if you could look at a study and believe it to be correct/true/unbiased. But that is no longer possible, most especially in the connected fields of heart disease, and nutrition.
'It is simply no longer possible to believe much of the clinical research that is published, or to rely on the judgement of trusted physicians or authoritative medical guidelines.” Marcia Angell – long-time editor of the NEJM.
'The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue���science has taken a turn towards darkness.' Richard Horton – editor of The Lancet.
'The poor quality of medical research is widely acknowledged, yet disturbingly the leaders of the medical profession seem only minimally concerned about the problems and make no apparent efforts to find a solution.' Richard Smith – long time editor of the BMJ.
It is always, of course, risky to base your thinking and conclusions on what is known about the basic science. New facts can come along to upend your thinking at any time. However, with mainstream medical research in such a corrupt mess, I do not know how else to do it. The basic research tells us that there is no mechanism whereby saturated fat can raise LDL levels, and the research, such as it can be disentangled, appears to fully support this.
I looked at this blog again, and again, and I thought: Why did I write it…for sure? I wrote it because I wanted to make you aware of three things. First, how powerful a thought can be. Saturated fat raises the LDL level, and how difficult this is to shift. The power of a simple idea.
Secondly, so that you can see that the truth is out there. It is not to be found amongst the experts in the field. It cannot be found by reading the research, or the guidelines. But it is out there, if you look hard enough.
Third, the mainstream just will not change its mind. A recent conference in Switzerland, organised by the BMJ, and others, tried to discuss the dietary guidelines and the role of Saturated fat. I was invited, but did not go, as I was working. Zoe Harcombe went, and wrote a blog about it.8 As she wrote about the conclusion of the conference:
'At the recent Swiss Re/The BMJ Food for Thought conference, the closing speakers tried to find some agreement on dietary fat guidelines…
Fiona (Fiona Godlee, editor of the BMJ) started with: “The point about saturated fat is: the evidence is now looking pretty good, but the guidance hasn't shifted… there doesn't seem to have been an enormous 'mea culpa' from the scientific community that we got it so wrong. That does surprise me.”
Salim replied: “We got brainwashed by a very questionable study, called The Seven Countries Study, many years ago and it was ingrained in our DNA and generations of us were brought up with that… Somebody said that you need to wait for guidelines committees to die before you can change the guidelines committees”!
Fiona then said: “Maybe one outcome of this meeting would be for this meeting to say 'that's gone now', the science has changed. Am I right Salim? Am I right Dariush? It seems to be that should be an outcome of some sort from this meeting.”
Alas, the UK guidelines committee shows no signs of such change, let alone the 'mea culpa' that Fiona suggests might be in order.'
Read the full article at DrMalcolmKendrick.org
References
1: https://www.diabetes.co.uk/in-depth/every-last-shred-evidence-low-fat-dietary-guidelines-never-introduced/
2: http://time.com/3705734/cholesterol-dietary-guidelines/
3: https://www.health.harvard.edu/blog/panel-suggests-stop-warning-about-cholesterol-in-food-201502127713
4: https://www.ncbi.nlm.nih.gov/pubmed/12133211
5: https://www.medscape.com/viewarticle/839360
6: https://www.pressreader.com/uk/daily-mail/20180109/282643212945759
7: http://bmjopen.bmj.com/content/8/3/e020167
8: http://www.zoeharcombe.com/2018/07/saturated-fat-consultation-sacn-my-response/
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Type II Diabetes Breakthrough
New Amazing Diabetes Breakthrough to Help Cure Type II Diabetes Diabetes is a serious medical condition that affects millions of Americans. Over 29 million Americans suffer from diabetes, that is one of every 11 people. One in four people who have diabetes don’t even know it, and a whopping 86 million people are prediabetic. It is a silent killer and if left untreated can cause serious health complications which include heart disease, stroke, blindness, kidney failure, and even death. As you can see diabetes is no joke. The good news is Type II diabetes can be controlled. I have found a new program which helps diabetics achieve their blood sugar goals without drugs. I had to write about it so that you and your loved ones can discover this revolutionary program for yourselves. Before we talk about the program, let’s go over the basics so you understand what diabetes is and what it does to your body. What is Type II Diabetes? Your body needs the hormone insulin to turn the sugar you eat into energy your body can use. Your pancreas produces insulin in your body to turn the sugar you eat into energy for your cells to use. People with Type I diabetes do not produce insulin, or don’t produce enough insulin to metabolize sugar. People with Type II diabetes produce insulin, but their bodies can’t use it. This is called insulin resistance. Your pancreas tries to compensate by producing extra insulin, but over time it can’t keep up with the demands and produce enough to keep your blood sugar levels normal. As your blood sugar rises (hypoglycemia) you may experience these symptoms: Frequent urination Increased thirst Increased hunger even after you eat Unexplained weight loss Fatigue Headaches Blurred vision Slow healing cuts or sores Frequent yeast infections Sweet smelling breath Loss of consciousness These are just a few of the symptoms of Type II diabetes. Diabetes manifests over time and you may experience symptoms and not even realize why which is one reason it is such a serious medical condition. How Type II Diabetes Puts Your Body at Risk Type II diabetes puts you at risk for several health complications. Kidney Damage Your kidneys are very susceptible to damage from diabetes. Your kidneys filter your blood and remove waste and impurities. If you have elevated protein levels in your urine, this could be a sign your kidneys are not working properly. This is known as diabetic nephropathy. Approximately 180,000 people with Type II diabetes suffer from some stage of kidney damage. Diabetes damages the small structures which filter waste called nephrons. Our kidneys have millions of nephrons. Diabetes can damage and scar these nephrons causing a protein called albumin to enter your urine. Your doctor measures the level of albumin in your urine to gauge how well your kidneys are working. Kidney damage comes on slowly and usually does not present symptoms until it has progressed to Stage 3 or Stage 4. If detected and treated early, the disease can be stopped or even reversed. Circulatory System Damage Diabetes puts you at greater risk for high blood pressure. This puts a strain on your heart. High blood sugar levels may lead to the formation of fatty deposits in your blood vessel walls. Over time this can restrict blood flow and lead to a hardening of the blood vessels, atherosclerosis. According to the National Institute of Diabetes and Digestive and Kidney Diseases, diabetes also doubles your risk for a heart attack and stroke. System Wide Damage An increased risk for kidney and circulatory damage are only two complications which can arise from diabetes. Some of the other risks include erectile dysfunction, skin conditions, nerve damage, and peripheral neuropathy. Peripheral neuropathy can affect your hands and your feet. It is a painful tingling sensation caused by nerve damage. Here’s the Good News Okay, enough doom and gloom. I am here to tell you about a revolutionary program that will reverse and control the effects of diabetes all without medications or insulin injections. A program which is all natural and has been proven to give many people relief from the complications and restrictions of Type II diabetes. Now, be clear this is for Type II diabetes, not Type I. Type I diabetics are insulin dependent and should NOT stop taking their insulin. That being said, if you have Type II diabetes or know of someone who does, I’m here to review and share information about a proven method of controlling blood sugar levels and keeping them at a healthy level. Several of my friends have used this program to control their blood sugar levels and live healthy vibrant lives. The Root Cause of Diabetes Type II Recently the researchers at the University of California San Diego made a shocking discovery. They discovered that an inflammation molecule known as LTB4 was responsible for insulin resistance, the hallmark of Type II diabetes. Inflammation is the root cause of Type II diabetes. This is why insulin and oral medications can’t cure or reverse the effects of diabetes. They don’t treat the root cause. Drugs and medications only treat the symptoms, not the cause. Only by treating inflammation can you counteract the effects of Type II diabetes and gain control over your blood sugar levels. The Answer I was shocked at how simple the answer truly is. In the book, The 7 Steps to Health and the Big Diabetes Lie, Max Sidorov and a group of medical doctors lead you through the steps you need to reduce inflammation in your body and be on the road to relief. No drugs, no weird foods, no stressful exercise regiments, just cold hard facts you can use. This book is easy to read and understand and it presents information anyone can use to improve their health and get off the pharmaceutical merry go round. I don’t want to sound like a commercial, that is not my intention. It’s just I’m so excited by this program I get a bit carried away. The difference I’ve seen in people’s lives is just amazing and I want you to experience this change, too. Find Foods in the Grocery Store to Reduce Inflammation By eating regular foods found in any corner grocer, you can reduce inflammation and be on your way to controlling Type II diabetes. The 7 Steps to Health and the Big Diabetes Lie shows you which foods and the correct portions are effective in combating diabetes. You will lower your cholesterol, blood sugar, blood pressure, and reduce inflammation in your body. You will learn nutrition tricks used by a Norwegian doctor to help his patients come completely off insulin and oral medications. The diet outlined in this book has been proven to be twice as effective as the diet recommended for diabetics by the American Diabetes Association. Real Results Using the step by step solution shared in this book 96 percent of patients ended their need for insulin medication in a study by University of Kentucky and the Veterans Affairs Medical Center. Safely lower your cholesterol by 25 to 39 percent without the use of prescription drugs. See why you are always hungry and the simple step to do away with your food cravings. Learn how high fructose corn syrup is ruining your health and why you need to cut it out of your diet for good. Learn how pharmaceutical companies skew research results in order to sell more prescriptions. For example, using young people and then selling to older patients. Did you know margarine really isn’t a healthy alternative to butter? Margarine is full of carcinogenic synthetic ingredients. A popular sweetener commonly used in processed foods promotes inflammation in your body and contributes to non-alcoholic fatty liver disease. Also learn how diet sodas and other diet products cause weight gain and blood sugar spikes, and how meal replacement and protein bars are not a healthy choice. Find out what spice you probably already have in your cupboard can increase sugar metabolism by an amazing 20-fold. Real People Tell Their Story All this and more is shared in The 7 Steps to Health and the Big Diabetes Lie. Seriously, you need to get this book. Don’t take my word for it, here are some testimonies from real people who have used this book to reverse Type II diabetes and its effects on the body. I am a type 2 diabetic, who also has high cholesterol. I have tried several medications (for both my diabetes and my high cholesterol) but just hated the side effects. I found this site while searching for alternative treatments. After changing my lifestyle quite a bit and doing everything in the book for nearly 3 months, I had my annual checkup. I did not say a word to my doctor about what I had been taking. When the lab results came back, he personally called me and I could tell that was obviously very excited. He asked me What the heck I had been doing because my glucose reading had gone down 32 points and my cholesterol profile had significantly improved as well. You've made a believer out of me and my doctor. Thank you so much! I am a 45 year old woman and was recently diagnosed as being a borderline diabetic. I knew something was wrong because, I have always been healthy my whole life, but of late began feeling exhausted all the time. My doctor prescribed some medication, but before filling it I decided to do some research on the internet which led me to the 7 Steps to Health. After reading your ebook and applying the methods, my skepticism turned to 100% belief. I noticed that my energy levels increased significantly and I felt more rested in the morning, my symptoms started going away and I was even losing weight. I am very happy to tell you that I have been feeling better than I have felt in years and my doctor informed me that he will be taking me off my prescriptions if I keep this up. This book is a godsend. -Sherry I have totally changed my eating habits as outlined in the 7 Steps to Health and am totally amazed at the results I have gotten, in such a short period of time. My blood sugar has averaged 103 over the past two weeks compared to the 160 I was averaging before. This is far better than I was expecting, particularly so soon. As you can imagine, I am delighted. - Alice I have been doing the 7 Steps to Health for 3 weeks now, and have noticed a significant improvement. I feel better than I have in years. My average glucose readings have gone from 12.5 - 16 mmol/L to 6 - 8.5 mmol/L. Obviously, I am quite pleased with the results so far. I have tried several other products advertised on the internet but they did not work like this, not even close. Thanks for showing us the path Max! – Donna I've been Diabetic for nearly a decade. My doctors prescribed me on Glucophage which I was taking 3 times a day to keep me between 140 and 175 points all day. After starting with 7 Steps to Health, I noticed that I was able to reduce the Glucophage to just 2 times a day and keep my sugar stabilized below 140 all day. By the end of my first month of all these nutrition interventions, I was able to reduce the Glucophage to 1 time per day and stay stable at 109-115. My doctor is happy. I've been following the 7 Steps to Health for 6 months now and I am stable around 90! My doctor was so impressed that he took me off the Glucophage completely. Thank you so much! Everyone should know about this wonderful ebook! God Bless. – Gary The Bottom Line If you are ready to get off the pharmaceutical bandwagon and control your Type II diabetes without insulin or prescription drugs you have to order The 7 Steps to Health and the Big Diabetes Lie ebook. I highly recommend it. What I like most about the program is you can change your life by eating foods you find in the grocery store and using certain spices and supplements. What could be easier? Are you ready to take control of your diabetes and live a full healthy life? I know you are, and The 7 Steps to Health and the Big Diabetes Lie is your key to success. So if you want your life back and cure your diabetes click here. http://exerciseandhealth.net/type-ii-diabetes-breakthrough/
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Facebook August 11, 2017 - This is a difficult update to make. I've been waiting until I had a few remaining pieces of information but I have enough to let you know what is going on.
As you know, I was diagnosed with toxic mold exposure and I am in Tampa at a facility that specializes in treating mold toxicity. The fact that there is a facility that has successfully treated hundreds of thousands of people is something I'm extremely grateful for.
You've seen pictures of the port through which I will get my treatment every day. Most likely beginning on Monday. All of this is good, and it's the positive I am clinging to right now.
The rest of the news is not unscary. I am sharing this without much censorship because I'm feeling afraid and even though I have a lot of love in my life, this is in many ways a solitary process and I want to feel a little less alone as I begin it.
This stuff won't be super easy to hear for those who love me very much - much less easy to say - and I'm sorry if it freaks anyone out... but here it is in all it's glory. These toxins, called mycotoxins (from mold exposure), that I am infected with, are extremely poisonous, because of what they do. This is what I have been learning about in excruciating detail.
1) They compromise the liver's ability to produce the enzymes needed for detoxification required to keep the body healthy. 2) They compromise the body and brain's immune systems. 3.) They destroy the blood brain barrier and gut lining. 4.) The destruction they cause allows parasites and bacteria into the blood, brain and nervous system cells; all of these organisms and toxins produce toxic matter while they simultaneously destroy healthy tissue and organs. I'll let that one sink in for a moment. :(
5) As this is occurring and the body is preoccupied with trying to keep itself running, the nervous system is inevitably exposed to additional environmental toxins (e.g., petrochemicals in the air and water which cause neurodegeneration, cancers, etc). And here is where it gets sad and scary. 6) As a result of all this toxicity and invasive organisms, cell walls are destroyed, premature death of vital cells happens with increasing speed and regularity, and mitochondrial function is totally compromised. (Mitochondria are essential to life, and mitochondrial dysfunction is responsible for many diseases you know the names of. Multiple sclerosis is one example.)
This chain reaction has happened because I am genetically unable to create immunity to mold. So this destructive chain of events has likely been underway a long time. There was standing water in our basement that we used to roller skate around. Many of our basements were musty as were my friends. And I lived in plenty of water damaged buildings and apartments. When Mom's basement flooded I was sitting amongst the mold growing on the walls and on our ruined photo albums for hours at a time for months, including after the mold was remediated (killed) which meant I was just marinating in mycotoxins. Many people have asked me why this is just now happening but it hasn't - it's been slowly creeping up.
Most people who have known me in the past 10 years have known me as a person with health problems. Panic attacks, increasing body pain and weakness, cognitive changes and sensitivity/electrical activity in my brain that no doctor could diagnose - until I found one trained in environmental medicine (which is not taught in medical school, apparently). The past year I have been unwell quite a lot, and in the past couple months have lost a lot of function as a result of this electrical activity in my nervous system.
I learned this week that this electrical activity is caused by biofilm which these many foreign organisms create and live in, inside the fatty tissues of the body - most importantly in the brain. This biofilm becomes an ecosystem, complete with communication from organism to organism, and functions with a lot of electrical activity independent of the brain's function and in response to the brain's function.
This is a photo of my brain - my precious and only brain - which is so electrified that even in a sleeping state it is never turned off. All that red and orange and yellow is activity - activity that should not be there in a resting state (which is the state in which the PET scan is taken - which required quite a lot of drugs to achieve just like sleep does for me, now, every night). The lower portion, from my understanding, is tissue, and anything not black is non-brain matter. So all that blue stuff is parasites and bacteria and mycotoxins and petrochemicals. :( I learned this week that all of this has led to significant organ damage; my liver is in early stages of failure, fatty tissue destruction in my brain/nervous system is occurring at a record rate (worst 5% of the population), and is on track for multiple sclerosis and scarier things I dare not even mention. The visual and hearing changes I am experiencing along with my balance/coordination issues and difficulty walking, etc are on the list of things that we will address in treatment.
Next week I will slowly begin the "kill" infusions to deal with all this foreign matter in my brain/nervous system/liver. I'm scared about it, because the body has to go through a very intense process to deal with this.
Various killing agents are introduced to kill bacteria and parasites, alongside various substances that bind to toxic matter and bring it out of the system. This is delicate business. I have seen much illness, weakness, seizures,etc, in my short time in the clinic.
But I have also seen dozens of people leaving having concluded their treatment ... and they are walking around even though many came in unable to walk at all. I see people talking and laughing who were catatonic when they came in. I said goodbye today to a really nice man who has the same mold genetics as me, who had to retrofit his entire house to make it safe to move back into. But he was able to do it. It took him 3 months to repair his immune system and cellular state/activity. I took a picture of him with his final IV drip and watched him get his port access closed for hopefully the last time. But while this was happening, a girl about 10 feet away was having her 3rd seizure this week (that I have seen), and the man with very bad Parkinson's (who also has bad mold genetics and had extremely high mold tests and astonishingly high levels of industrial toxins) was crying softly for a very long time.
So nobody is pulling any punches - it's clear that I will have good days and bad days. But the people who stick with it get better. There are literally thousands of before and after pictures on the walls of people who, with the help of these doctors, were able to break through the biofilm, kill the foreign organisms in their brains/nervous systems, restore healthy gut and brain barriers, rebuild cell walls and repair mitochondrial function, reverse autoimmunity and leave with functioning immune and detoxification systems. And all along the way what's happening is explained and the research and outcomes supporting the approach is readily available and extensive.
It might be very hard but if these other people can have these outcomes, I have good reason to be hopeful. And it's time. Because its very hard to watch those closest to me suffer while I have been suffering. And because I want to have a positive active, happy life again. I want to have a family, and to spend time with my friends and my relatives who miss me, and whom I miss. All of you, for example.
I am so grateful to those of you who have reached out to the incredibly special people who have been supporting me during this time. I wish I could be taking more care of the people I love right now the way I used to. I feel sad about the modifications my loved ones are having to make to their own lives. I keep telling myself this is all happening to make us all stronger in the end. For now I just feel alternately grateful and also sorrowful for the circumstances.
Thanks for all your thoughts and prayers - but please try not to worry. I believe in the underlying energetics of things (don't get me started on the energetics of mold) and I know that only positive energy best be pointing in my direction. I will be doing - am doing - all I can on my side to focus on the positive* as well.
*This might seem like a gloomy update but this process is the first time I have ever opened up so candidly about something so personal, so I consider this a positive step.
I am thankful to you for reading this and for all the care, kind thoughts, wishes and prayers I am lucky enough to be receiving. I really love you all, and I look forward to the day we can talk and hang out again soon.
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