#hmec

[kamilapetelin]

⋆⭒˚.⋆ Aula 12 - HMEC ⋆⭒˚.⋆

14/11

Rotina: ♡ Síntese provisória

Faltei por motivos de: ida ao psiquiatra (estava precisando)

[r7inyz]

WHY DO I ALWAYS GET INSANE MOTIVATION TO DRAW WHEN IM SUPPOSED TO BE STUDYING FOR EXAMS RAAAAAAAH 🍅🍅🍅🍅🍅🍅👎👎👎👎👎👎

[allo-ho-mora]

anyone who leaves pins in while using a sewing machine is terrifying

[industrynewsupdates]

Protein Ingredients Market Business Analysis, Recent Development And Forecast, 2030

The global protein ingredients market size was valued at USD 77.69 billion in 2022 and is expected to grow at a revenue-based compound annual growth rate (CAGR) of 5.8% from 2023 to 2030. 

The market is gaining momentum and witnessing a high demand owing to rising demand for food products, such as margarine, cold cuts, bakery products, spreads, yogurt, and milk sausages, which are produced using protein ingredients. Increasing consumption of these products among health-conscious and elderly consumers is also fueling the industry’s growth. Moreover, a rise in the innovation of several proteins by various manufacturers that constitute a wide range of amino acids and perform specific functions, including satiety, muscle repair, weight loss, and energy balance, is expected to present immense growth opportunities for the market.

The industry has witnessed a considerable increase in the consumption of animal-based products in the recent past. Animal protein is expected to witness further growth over the next few years in the U.S. Momentous demand for these products derived from animal sources in the domestic market is expected to ascend the product demand. The supply chain initiatives undertaken by the ingredient manufacturing companies to strengthen the distribution of products are further expected to drive the market over the forecast period.

Gather more insights about the market drivers, restrains and growth of the Protein Ingredients Market

Protein Ingredients Market Report Highlights

• By product, plant proteins are expected to witness the fastest growth over the forecast period owing to the increased use of protein ingredients in food and beverages. Increasing use of plant proteins in a wide range of applications, including manufacturing of fertilizers, paper coatings, and printing inks, is creating lucrative growth opportunities for the segment

• Animal/dairy proteins held the largest revenue share of over 78.94% in 2022 owing to the growing adoption of these products in developed markets. Whey protein is expected to witness significant growth over the forecast period as it is largely popular among fitness-savvy consumers

• North America dominated the market with more than 33.56% share of the global revenue in 2022 owing to the high demand from the U.S. food and beverages sector. Consumer markets developing in Asia Pacific are growing at a high pace due to a rise in disposable income and changing lifestyle, resulting in significant growth of the regional market

• The Middle East and Africa is expected to exhibit a revenue-based CAGR of 9.6% from 2021 to 2028. This is attributed to supportive government policies as well as improved economic indicators, which have resulted in the increased availability of packaged foods amongst the urban and rural population

Browse through Grand View Research's Nutraceuticals & Functional Foods Industry Research Reports.

• The global fermented ingredients market size was valued at USD 35.3 billion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 11.1% from 2024 to 2030.

• The global milk protein market size was estimated at USD 6.63 billion in 2023 and is projected to grow at a CAGR of 3.2% from 2024 to 2030.

Protein Ingredients Market Segmentation

Grand View Research has segmented the protein ingredients market based on product, application, and region:

Protein Ingredients Product Outlook (Volume, Kilotons; Revenue, USD Million, 2017 - 2030)

• Plant Proteins

o Cereals

o Wheat

o Wheat Protein Concentrates

o Wheat Protein Isolates

o Textured Wheat Protein

o Hydrolyzed Wheat Protein

o HMEC/HMMA Wheat Protein

o Rice

o Rice Protein Isolates

o Rice Protein Concentrates

o Hydrolyzed Rice Protein

o Others

o Oats

o Oat Protein Concentrates

o Oat Protein Isolates

o Hydrolyzed Oat Protein

o Others

o Legumes

o Soy

o Soy Protein Concentrates

o Soy Protein Isolates

o Textured Soy Protein

o Hydrolyzed Soy Protein

o HMEC/HMMA Soy Protein

o Pea

o Pea Protein Concentrates

o Pea Protein Isolates

o Textured Pea Protein

o Hydrolyzed Pea Protein

o HMEC/HMMA Pea Protein

o Lupine

o Chickpea

o Others

o Roots

o Potato

o Potato Protein Concentrate

o Potato Protein Isolate

o Maca

o Others

o Ancient Grains

o Ancient Wheat

o Quinoa

o Sorghum

o Amaranth

o Chia

o Millet

o Others

o Nuts & Seeds

o Canola

o Canola Protein Isolates

o Hydrolyzed Canola Protein

o Others

o Almond

o Flaxseeds

o Others

o Animal/Dairy Proteins

o Egg Protein

o Milk Protein Concentrates/Isolates

o Whey Protein Concentrates

o Whey Protein Hydrolysates

o Whey Protein Isolates

o Gelatin

o Casein/Caseinates

o Collagen Peptides

o Microbe-based Protein

o Algae

o Bacteria

o Yeast

o Fungi

o Insect Protein

o Coleoptera

o Lepidoptera

o Hymenoptera

o Orthoptera

o Hemiptera

o Diptera

o Others

Order a free sample PDF of the Protein Ingredients Market Intelligence Study, published by Grand View Research.

[fitness-trending-content]

Ep. 20 Fitness to Thai Hmec 🇺🇳🇸🇸🇹🇭#gym #fitness #fyp #shorts #army 💪🏋️‍♀️🇺🇳 https://newsinfitness.com/ep-20-fitness-to-thai-hmec-gym-fitness-fyp-shorts-army/

[kamilapetelin]

⋆⭒˚.⋆ Aula 14 - HMEC ⋆⭒˚.⋆

7/11

Rotina: ♡ Consulta de retorno: Dolores

Sentimentos sobre minha participação: Fofoca: Ana é uma menina perfeccionista. Não daquele tipo ''entrevista de emprego'', estou me referindo a REALMENTE perfeccionista, beirando a ganhar um CID de presente.

Então, enquanto a Carol treinava exame físico em sua cobaia (eu) a Ana constantemente interrompia para corrigir. O que irritou profundamente a Carol.

No fim, ninguém brigou com ninguém (por pouco, bem pouco)

Das 3 consultas, acho DPOC a mais difícil de abordar

A orientação para interrupção do tabagismo é essencial, pois este causa destruição do tecido pulmonar (enfisema) e obstrução das pequenas vias aéreas com inflamação e muco (bronquite crônica), levando a sintomas cardinais da DPOC, ou seja, falta de ar e tosse. Todos os indivíduos que fumam devem ser identificados e incentivados a deixar de fumar. Também, evitar permanecer em ambientes com poluição do ar e outros fatores precipitantes. A vacinação contra a gripe e outras doenças respiratórias podem reduzir o risco de exacerbações graves: vacina contra o sarscov2, anti-influenza e vacina pneumocócica polivalente. A avaliação do estado nutricional e da função músculo- esquelética é necessária para melhora da tolerância ao exercício e do estado geral de saúde desses pacientes, atualmente há evidências que a atividade física pode resultar nestas melhoras. A atividade física deve ser tanto o exercício aeróbio quanto o treino de força. O exercício aeróbio é recomendado e deve ser iniciado independentemente do estágio da DPOC em que o paciente se encontra.  O treino de força objetiva melhorar a fraqueza muscular que contribui para a intolerância ao exercício em portadores de doença pulmonar crônica, o exercício de força é uma opção racional no processo de reabilitação pulmonar. Na Atenção Primária à Saúde (APS) é importante o diagnóstico precoce e a utilização concomitante do tratamento medicamentoso e o não medicamentoso, para impedir ou retardar a evolução clínica do DPOC. https://aps-repo.bvs.br/aps/qual-o-tratamento-para-doenca-pulmonar-obstrutiva-cronica-dpoc-na-aps-2/

Sentimentos sobre os professores: Incrível a Rafa dando feedback e se admirando no vidro espelhado ao mesmo tempo, eu faria o mesmo se fosse bonitona assim kkkk

Sentimentos sobre a turma: Eu, particularmente, gosto como a Carol se comunica e a voz dela é muito bonita, traz conforto.

Teria informado que iria conversar com a doutora Soraya sobre solicitar espirometria, afinal é necessário para estabelecer diagnóstico. Também teria explicado sobre DPOC para o paciente.

Esse PDF é maravilhoso: https://www.spmi.pt/wp-content/uploads/2023/06/Roteiro_DPOC.pdf

(つ≧▽≦)つ fim

[juniperpublishers-jdvs]

Secrets of Mammary Stem Cells Secretome-Juniper Publishers

JUNIPER PUBLISHERS-OPEN ACCESS JOURNAL OF DAIRY & VETERINARY SCIENCES

Abstract

The role of mammary stem/progenitor cells and its secreted proteins in therapeutic application has not been evaluated yet. Here, author reviewed information pertaining to secreted proteins of mammary epithelial cells and mammary stem/progenitor cells and supported their ideas that secretome could potentially be explored for natural antimicrobials against supportive therapy of bovine mastitis.

Keywords: Mammary stem cell; Secretome; Mastitis; Bovine; Spectrophometer; Proteins; Laboratory; Lactoferrin; Receptors; Biomarkers; Pacific; Population; Antibiotics; Progenitor cells

Abbrevations: HMEC: Human Mammary Epithelial Cells; CM: Conditioned Medium; EGFR: Epidermal Growth Factor Receptor; AFDC: Adherent Fraction Derived Cells; MDC: Mammosphere Derived Cells; TGFβ: Transforming Growth Factor Beta; MDBK: Madin Darby Bovine Kidney Epithelial; LPS: Lipopolysaccharides

Opinion

Secretome are the cell secreted proteins released in the cell extracellular space. Groups of proteins present in the secretome are involved in signalling and cell communications. Study of such proteins, thus would be helpful in understanding the niche of the cell. Researchers of Pacific Northwest National Laboratory, Washington probably was the first group which demonstrated secretome of human mammary epithelial cells (HMEC) in 2008 [1]. They identified secretome of human mammary epithelial cells (HMEC)-conditioned medium (CM) cell lysates and showed regulation of matrix metalloproteases through epidermal growth factor receptor (EGFR). In 2009, Simpson and co-investigators have profiled three different secretome of basal MaSC, luminal progenitors and mature luminal cell lines. In this study, in addition to enriched expression of ephrin receptors and integrins, the activity of Wnt signalling pathway was uniquely detected in the MaSC [2]. In a recent publication of Scientific Reports journal, researchers from Cornell University, Ithaca, NY has defined secretome of mammosphere derived MaSC and opened up new doors for the possible treatment of bovine mammary gland infections [3].

For their studies, the team isolated cultured two different populations of bovine mammary cells- adherent fraction- derived cells (AFDC) and suspension mammosphere-derived cells (MDC). These two cell population were immunopheno typically different as analyzed by various cell surface markers. However, the expression of CD44 and CD49f was higher in MDC CM than the AFDC CM. Level of CD29 was high in CM of both these cells. Proteome analyses of AFDC and MDC CM, using mass spectrophometer, revealed 347 and 537 matched proteins and peptides functionally related to defense and immunity and tissue regeneration like angiogenesis and cell migration. Furthermore, two antimicrobial proteins namely lactoferrin and cathelicidine have been validated and quantified using Western blot (Figure 1) and observed differential expression of the proteins in CM of MDC versus AFDC. Two angiogenesis factors namely, angiopoetin 1 and vascular endothelial growth factor alpha, angiopoetin 1 showed high expression level in MDC CM. Likewise, levels of proteins involved in cell migration (transforming growth factor beta (TGFβ), Insulin-like growth factor-1 and hepatocyte growth factor) were estimated in the CM and found that the concentration of TGFβ was high in CM of MDC. TGFβ induces epithelial cell to mesenchymal type and promotes cell migration. Taken together, this study showed CM of AFDC and MDC contains various proteins which have roles in tissue regeneration and immune defence of the host.

Interestingly, proteins of AFMC and MDC also contained factors which protects bacterial toxin-induced MEC death. Loss of MEC damage is an important consequence of mastitis and it is induced by the toxins of Gram-positive bacteria and lipopolysaccharides (LPS) of Gram-negative bacteria. A significant reduction in growth of bacteria (measured by optical density) was observed when Madin-Darby Bovine Kidney Epithelial (MDBK) cells were grown in presence of Klebsiella (a Gram-negative bacteria) and Staphylococcus aureus (a Grampositive bacteria) in presence of MDC CM. The researchers also evaluated shelf-life of MDC CM for one week and found that frozen CM is biologically effective on MDBK cell migration. The storing of CM for long time would be advantageous for future clinical use in mastitis management even at remote places.

In summary, these studies providing rationale for the potential use of MDC secretome as supportive or adjunct therapy in bovine mastitis. Secretome could be an ideal biological source for naturally occurring anti-microbial and potentially beallogenically safe like antibiotics. In future, an important follow-on studies should include evaluation of novel proteins as biomarkers and identification of newly identified proteins with no to little annotations. In vivo application of MDC secretome in management of naturally occurring bovine mastitis, also warranted future investigations.

For more Open Access Journals in Juniper Publishers please click on: https://juniperpublishers.com/open-access.php

For more articles in 

Open Access Journal of Dairy & Veterinary sciences

 please click on:

https://juniperpublishers.com/jdvs/index.php

[famouszombieobject]

Chicken Elisa Kits

Ondanks het opkomende succes van multi-gerichte proteïne-tyrosinekinase (PTK) -remmers bij kankertherapie, lijkt het onwaarschijnlijk dat significante bijwerkingen en zorgen over resistentie worden vermeden. Het doel van de huidige studie was om nieuwe multi-targeting PTK-remmers te identificeren. De enzymatische activiteiten van kinase werden gemeten door middel van enzymgekoppelde immunosorbent-assay (ELISA). 

De antiproliferatieve activiteiten in menselijke microvasculaire endotheelcellen (HMEC's) werden geëvalueerd door middel van sulforhodamine (SRB) -test. De fosforylering van kinasen en hun stroomafwaartse moleculen werd onderzocht door middel van Western blot-analyse. De bindingsmodus tussen MdOS en PTK's werd geprofileerd door oppervlakte-plasmonresonantie (SPR) -benadering en moleculaire simulatie. Buisvormingstest, aorta-ringmethode bij ratten en chorioallantoïsmembraanproef bij kippen werden gecombineerd om de in vitro en in vivo anti-angiogene effecten te illustreren.

 De resultaten gaven aan dat MdOS, een nieuw van zee afgeleid oligosaccharidesulfaat, een PTK-remmende werking met een breed spectrum vertoonde. Op enzymatisch niveau remde MdOS HER2, EGFR, VEGFR, PDGFR, c-Kit, FGFR1 en c-Src, met weinig impact op FGFR2.

[latinboxsports]

@wbsuperseries Is Back!! • 🚨 CONFIRMED: @mairisbriedis vs @DorticosKO - #WBSS Cruiserweight Final - set for 26 September! 🔥🔥 The hotly-anticipated World Boxing Super Series Season II Cruiserweight Final between Mairis Briedis and Yuniel Dorticos takes place behind-closed-doors in Munich, Germany on Saturday, 26 September 2020. The culmination of the quest for the Muhammad Ali Trophy will be held in a television studio under Covid-19 rules and with no spectators at Plazamedia Broadcasting Center, a leading live sports production house in Munich. #BriedisDorticos 🏆 #AliTrophy https://www.instagram.com/p/CE4vMr-hMEc/?igshid=i1vu9iwkevad

[newsoutbursts]

Temples in North America to hold virtual prayer to celebrate Ram Temple's foundation laying ceremony

Temples in North America to hold virtual prayer to celebrate Ram Temple’s foundation laying ceremony

Washington: Hindu temples in North America will hold a virtual national prayer to celebrate the foundation laying ceremony of the Ram Temple in Ayodhya, religious groups have announced.

The Hindu MandirExecutives’ Conference (HMEC) and the Hindu Mandir Priests’ Conference (HMPC), in a statement on Friday, called for a virtual collective national prayer across America to rejoice the upcoming…

[kamilapetelin]

⋆⭒˚.⋆ Aula 13 - HMEC ⋆⭒˚.⋆

31/10

Rotina: ♡ Oficina Suporte Básico de Vida

Sentimentos sobre minha participação: Story Time: Há uns anos estava voltando do mercado com a minha mãe, quando uma multidão começou a gritar e se desesperar. Um bebê havia se engasgado e não estava respirando.

Eu não sabia o que fazer, acabaram levando ele pro hospital e não sei o que aconteceu depois.

Decidi prestar MUITA atenção nessa aula pra não me sentir impotente novamente. Agora eu sei o que fazer.

Descobri que Never Gonna Give You Up tem 120 BPM e o refrão dá 30 compressões certinho.

Sentimentos sobre os professores: Achei engraçadinho a Rafa se atrapalhando na hora da encenação kkk mas foi tudo bem esclarecedor, saí de lá sem dúvidas

Sentimentos sobre a turma: Fiz grupo com a Chris e a Mi, elas são doutoras e palestrantes, me ensinaram bastante e ainda tiraram uma foto linda minha.

Esqueci minha jaqueta na sala essa dia e nunca mais acharam ╰(ಥдಥ)ノ

♡(ﾐ ᵕ̣̣̣̣̣̣ ﻌ ᵕ̣̣̣̣̣̣ ﾐ)ﾉ fim

[ursumartins]

#fiqueemcasa https://www.instagram.com/p/B-Atwc-hMEc/?igshid=xbgtqdwagw06

[juniperpublishers-jdvs]

Secrets of Mammary Stem Cells Secretome- Juniper Publishers

Abstract

The role of mammary stem/progenitor cells and its secreted proteins in therapeutic application has not been evaluated yet. Here, author reviewed information pertaining to secreted proteins of mammary epithelial cells and mammary stem/progenitor cells and supported their ideas that secretome could potentially be explored for natural antimicrobials against supportive therapy of bovine mastitis.

Keywords: Mammary stem cell; Secretome; Mastitis; Bovine; Spectrophometer; Proteins; Laboratory; Lactoferrin; Receptors; Biomarkers; Pacific; Population; Antibiotics; Progenitor cells

Abbrevations: HMEC: Human Mammary Epithelial Cells; CM: Conditioned Medium; EGFR: Epidermal Growth Factor Receptor; AFDC: Adherent Fraction Derived Cells; MDC: Mammosphere Derived Cells; TGFβ: Transforming Growth Factor Beta; MDBK: Madin Darby Bovine Kidney Epithelial; LPS: Lipopolysaccharides

Opinion

Secretome are the cell secreted proteins released in the cell extracellular space. Groups of proteins present in the secretome are involved in signalling and cell communications. Study of such proteins, thus would be helpful in understanding the niche of the cell. Researchers of Pacific Northwest National Laboratory, Washington probably was the first group which demonstrated secretome of human mammary epithelial cells (HMEC) in 2008 [1]. They identified secretome of human mammary epithelial cells (HMEC)-conditioned medium (CM) cell lysates and showed regulation of matrix metalloproteases through epidermal growth factor receptor (EGFR). In 2009, Simpson and co-investigators have profiled three different secretome of basal MaSC, luminal progenitors and mature luminal cell lines. In this study, in addition to enriched expression of ephrin receptors and integrins, the activity of Wnt signalling pathway was uniquely detected in the MaSC [2]. In a recent publication of Scientific Reports journal, researchers from Cornell University, Ithaca, NY has defined secretome of mammosphere derived MaSC and opened up new doors for the possible treatment of bovine mammary gland infections [3].

For their studies, the team isolated cultured two different populations of bovine mammary cells- adherent fraction- derived cells (AFDC) and suspension mammosphere-derived cells (MDC). These two cell population were immunopheno typically different as analyzed by various cell surface markers. However, the expression of CD44 and CD49f was higher in MDC CM than the AFDC CM. Level of CD29 was high in CM of both these cells. Proteome analyses of AFDC and MDC CM, using mass spectrophometer, revealed 347 and 537 matched proteins and peptides functionally related to defense and immunity and tissue regeneration like angiogenesis and cell migration. Furthermore, two antimicrobial proteins namely lactoferrin and cathelicidine have been validated and quantified using Western blot (Figure 1) and observed differential expression of the proteins in CM of MDC versus AFDC. Two angiogenesis factors namely, angiopoetin 1 and vascular endothelial growth factor alpha, angiopoetin 1 showed high expression level in MDC CM. Likewise, levels of proteins involved in cell migration (transforming growth factor beta (TGFβ), Insulin-like growth factor-1 and hepatocyte growth factor) were estimated in the CM and found that the concentration of TGFβ was high in CM of MDC. TGFβ induces epithelial cell to mesenchymal type and promotes cell migration. Taken together, this study showed CM of AFDC and MDC contains various proteins which have roles in tissue regeneration and immune defence of the host.

Interestingly, proteins of AFMC and MDC also contained factors which protects bacterial toxin-induced MEC death. Loss of MEC damage is an important consequence of mastitis and it is induced by the toxins of Gram-positive bacteria and lipopolysaccharides (LPS) of Gram-negative bacteria. A significant reduction in growth of bacteria (measured by optical density) was observed when Madin-Darby Bovine Kidney Epithelial (MDBK) cells were grown in presence of Klebsiella (a Gram-negative bacteria) and Staphylococcus aureus (a Grampositive bacteria) in presence of MDC CM. The researchers also evaluated shelf-life of MDC CM for one week and found that frozen CM is biologically effective on MDBK cell migration. The storing of CM for long time would be advantageous for future clinical use in mastitis management even at remote places.

In summary, these studies providing rationale for the potential use of MDC secretome as supportive or adjunct therapy in bovine mastitis. Secretome could be an ideal biological source for naturally occurring anti-microbial and potentially beallogenically safe like antibiotics. In future, an important follow-on studies should include evaluation of novel proteins as biomarkers and identification of newly identified proteins with no to little annotations. In vivo application of MDC secretome in management of naturally occurring bovine mastitis, also warranted future investigations.

To know more about  journal of veterinary science impact factor: https://juniperpublishers.com/jdvs/index.php

To know more about Open Access journals Publishers: Juniper Publishers

[artabovereality]

This year Halloween fell on a weekend Me and Geto Boys are trick-or-treating Robbing little kids for bags Till a old man got behind our ass So we speeded up the pace Took a look back and he was right before our face He'd be in for a squabble no doubt So I swung and hit the nigga in his mouth He was going down we figured But this wasn't no ordinary nigga He stood about six or seven feet Now that's the nigga I'd be seeing in my sleep So we triple-teamed on him Dropping them motherfucking B's on him The more I swung, the more blood flew Then he disappeared and my boys disappeared too Then I felt just like a fiend It wasn't even close to Halloween It was dark as fuck on the streets My hands were all bloody, from punching on the concrete God damn homey My mind is playing tricks on me. - #BushwickBill • Rest In Peace to Bushwick Bill of the legendary #GetoBoys. 📷 by Unknown. • #ArtAboveReality #LookWhatArtFound #Inspiring #Art #Curator #ContemporaryArt #FineArt #ArtMarket #ContemporaryPainting #CollectArt #ContemporaryArtCollectors #LiveWithArt #ArtConsultant #ShotOniPhone #ContemporaryArtist #ArtistsOnInstagram https://www.instagram.com/p/ByftlM-Hmec/?igshid=vbmx5uy2wbw7

[launch-3-telecom]

FGS-HMEC- 56C #adc1138660 #1138660. View here: https://t.co/XDgs6KfaHQ

[2karus]

■ #mhealthcoin ■

https://t.me/mHealthAirdropBot?start=490735422

■1400(14$) #HMEC    per ref+100 

#airdrop #bounty #btc #neo #eth #freetoken #crypto #xrp #blockchain #ripple #trx #ico #eos #exchange #zero #wallet