#haffkine

[jstor]

Explore the world of early bacteriological research with this historical footage from the Wellcome Trust, now available on JSTOR. This short film, dating back to between 1910 and 1919, showcases the movement and agglutination of typhoid and cholera bacilli, providing a rare glimpse into the origins of modern bacteriology. Believed to be one of the earliest surviving film records of this type, it highlights cultures possibly from the Bombay Plague Laboratory (now the Haffkine Institute for Training, Research & Testing). Dive into this unique piece of scientific history. Clip: Bacillus Typhosus (Typhoid and Cholera Bacilli). Wellcome Collection.

[marykk1990]

My next post in support of Ukraine is:

I'm going to start a new thing for my thread. While we will still visit places in Ukraine, I am going to do some posts about Ukrainians. I have talked about some Ukrainians in the thread before, but usually in relation to whatever site we were visiting at that time. But now I want to actually focus on actual Ukrainians. And, the first person I'm going to tweet about is Volodymyr Khavkin (also known as Vladimir Khavkin & Waldemar Haffkine). He was born in 1860 in Odesa & died in 1930 in Lausanne, Switzerland. Volodymyr Khavkin was a world-renowned bacteriologist who developed the world's first vaccines against plague and cholera. In 1897, he created a vaccine that treated bubonic and pulmonary plague. He traveled to India in 1893, where he set up vaccine production and vaccinated 42,000 people himself. Quoting my source, which I will also attach, "His groundbreaking research laid the foundation for modern vaccine development and served as a testament to the power of scientific innovation that was ahead of its time." The article also talks about four other important Ukrainians whom I will post about at a later time.

#StandWithUkraine

#СлаваУкраїні 🇺🇦🌻

The reason I say I have talked about some Ukrainians in the thread before is because I actually started a thread on Twitter about Ukraine on the first day of the full-scale invasion and I'm still posting it there. I just copied and pasted what I just posted to my Twitter Ukraine thread this evening.

[mymelodic-chapel]

Cherry People- Cherry People (Psychedelic Pop, Sunshine Pop) Released: 1968 [Heritage Records] Producer(s): Barry Oslander, Ron Haffkine

[healthcarehubhh]

"Anti Venom Market to Generate Lucrative Opportunities owing to Rising Prevalence of Snake Bite Cases"

The anti venom market has grown steadily owing to increasing number of snake bite cases across the globe. Anti venoms are biotechnological products used for pre-clinical and clinical treatment of envenomation, also known as snake bites. The rising incidence of snake bites and availability of effective anti-venom treatments have augmented the demand for anti venoms over the years. The global anti venom market is estimated to be valued at US$ 9229.16 Mn in 2024 and is expected to exhibit a CAGR of 6.7% over the forecast period of 2023 to 2030. Key Takeaways Key players: Key players operating in the anti venom market include Bharat Serums and Vaccines Limited (BSV), Boehringer Ingelheim International GmbH, Boston Scientific Corporation, CSL Limited, Haffkine Bio-Pharmaceutical Corporation Limited, Incepta Pharmaceuticals Limited, Merck & Co. Inc., Merck KGaA, MicroPharm Limited, Pfizer Inc., and Rare Disease Therapeutics Inc. Growing demand: The increasing prevalence of snake bites across tropical and sub-tropical regions has significantly driven the demand for anti venoms in the last few years. As per the World Health Organization (WHO), there are an estimated 5.4 million snakebites every year, resulting in around 2.7 million cases of envenomings and around 100,000 deaths.

[helthcareheven]

Snakebite Shield: Market Trends in Anti-Venom Solutions

The anti venom market is defined as the market for pharmaceutical products used to treat snake, spider or scorpion envenomations (snake bites). Anti venom drugs are serum-derived pharmaceutical products used to neutralize the toxicity of venom in cases of venomous snake, spider, or scorpion bites. Anti venom serums are biologics manufactured through pharmaceutical approaches. They are extracted from the horse or sheep that has been injected with non-lethal doses of snake venom. The resultant antibodies present in the blood serum of the injected animal can counteract and neutralize the effects of venom when given to envenomed humans or animals. The increasing frequency of venomous snake and scorpion bites has led to a greater emphasis on developing effective anti venom treatments, thereby driving market growth.

The Global anti venom market is estimated to be valued at US$ 9229.16 Mn in 2024 and is expected to exhibit a CAGR of 6.7% over the forecast period 2023 to 2030. Key Takeaways Key players operating in the anti venom market are Bharat Serums and Vaccines Limited (BSV), Boehringer Ingelheim International GmbH, Boston Scientific Corporation, CSL Limited, Haffkine Bio-Pharmaceutical Corporation Limited, Incepta Pharmaceuticals Limited, Merck & Co. Inc., Merck KGaA, MicroPharm Limited, Pfizer Inc., and Rare Disease Therapeutics Inc. These players are focusing on expanding their geographical presence and product offerings through strategic partnerships and acquisitions to maintain their leading positions in the market. The rising incidence of snake and other venomous animal bites globally presents significant opportunities for players in the anti venom market. As per the WHO, around 5.4 million snakebites occur each year, resulting in approximately 2.7 million cases of envenomings and around 138,000 deaths. Developing regions such as Asia Pacific, Latin America and Africa account for the majority of global snakebite cases due to agricultural practices, climatic conditions and lack of healthcare access in rural areas. Globally, companies are focusing on expanding their presence in emerging markets to meet the growing demand from countries such as India, Brazil, South Africa and Australia which report high rates of snakebite incidences. Manufacturers are also engaging in collaborations with regional venom suppliers, research institutes and healthcare providers to strengthen their supply chains and product access in these regions. Market Drivers One of the major drivers for the anti venom market is the increasing prevalence of snake and scorpion bites globally, especially in developing regions. It is estimated that around 5 million people experience snakebites each year according to the World Health Organization (WHO). Countries such as India, Brazil, Nigeria, Mexico and Afghanistan report high rates of snakebite cases attributable to climatic conditions favoring snakes and lack of access to healthcare in rural areas. The increasing agricultural and construction activities in rural regions also lead to greater interaction between snakes and humans, resulting in more envenomings. Market Restraints The major restraint for the anti venom market is the high costs associated with anti venom production. Since anti venom drugs are mostly serum derived pharmaceuticals, their production requires maintaining large farms of venomous snakes and horses or other animals to produce anti venom antibodies. This makes the manufacturing process very expensive and resource intensive. Additionally, variations in snake venom composition across geographic regions also necessitate development and clinical testing of region-specific anti venoms further adding to R&D costs. Strict regulations for ensuring the safety, efficacy and purity of anti venoms also contribute to high production costs. These factors make anti venoms unaffordable for populations in developing countries where they are needed the most.

Segment Analysis The Anti-Venom Market is dominated by the snake anti-venom segment which holds a market share of more than 60%. Snake bites account for a majority of venomous bites across the world, especially in Asia, Africa and Latin America. The higher prevalence of snake bites and the severity of envenoming caused by snake venom makes snake anti-venom the most prescribed treatment. Within snake anti-venom, the vials for polyspecific anti-venom continue to be the top-selling sub-segment due to their effectiveness against multiple snake species. Global Analysis Regionally, the Asia Pacific anti-venom market accounted for the largest share of more than 35% of the global market in 2023. Higher prevalence of snake bites and scorpion stings in countries such as India and Southeast Asian countries is a major factor driving market growth. Additionally, lack of advanced healthcare infrastructure in rural regions increases the demand for anti-venoms for treating venomous bites. North America is projected to witness the fastest growth during the forecast period owing to ongoing research and development of advanced anti-venoms for treating rare venomous bites. Key players are also focusing on expanding their operations in emerging markets of Latin America and Africa to tap into new revenue sources.

[my-chaos-radio]

Release: April 4, 1979

Lyrics:

When you're in love with a beautiful woman

It's hard

When you're in love with a beautiful woman

You know it's hard (it's hard, you know it gets so hard)

Everybody wants her, everybody loves her

Everybody wants to take your baby home

When you're in love with a beautiful woman

You watch your friends

(You watch your friends, you better watch your friends)

When you're in love with a beautiful woman

It never ends (it never ends, you know it never ends)

You know that it's crazy, you wanna trust her

Then somebody hangs up when you answer the phone

When you're in love with a beautiful woman

You go it alone

Maybe it's just an ego problem

Problem is I've been fooled before

By fair-weather friends and faint hearted lovers

And every time it happens, it just convinces me more

When you're in love with a beautiful woman

You watch her eyes (watch her eyes, baby, watch her eyes)

When you're in love with a beautiful woman

You look for lies (keep lookin' for lies, baby, look for lies)

Everybody tempts her, everybody tells her

She's the most beautiful woman they know

When you're in love with a beautiful woman

You go it alone

When you're in love with a beautiful woman

You watch your friends (you watch your friends)

(You better watch your friends, you better look out)

When you're in love with a beautiful woman

Oh, it never ends (it never ends, you know it never ends)

Songwriter: Even Stevens

When you're in love with a beautiful woman

You watch her eyes (watch her eyes, baby, watch her eyes)

(You better watch her eyes)

When you're in love with a beautiful woman

Keep lookin' for lies (keep lookin' for lies, keep lookin' for lies)

When you're in love with a beautiful woman...

SongFacts:

“When You're in Love with a Beautiful Woman” is an internationally successful single by Dr. Hook. It was recorded at Muscle Shoals Sound Studio, Alabama.

Written by Even Stevens, who followed producer Ron Haffkine into the studio bathroom to introduce him to the song "When You're in Love with a Beautiful Woman", which first appeared on the band's 1978 album Pleasure and Pain. Riding on the disco wave in 1979, it belatedly became an international hit, reaching number six on the Billboard Hot 100 singles chart in the US and doing even better in the UK, where it spent three weeks at number in November 1979 one of the British singles charts. The song was subsequently added to the band's 1979 album "Sometimes You Win."

[omkarpatel]

Rabies Antiserum Market is Estimated to Witness High Growth Owing to Opportunity to Treat Rabies.

Rabies antiserum is a lifesaving biologic product used to treat rabies exposure in humans. It contains rabies antibodies produced in animals that provide immediate short-term protection against the rabies virus until the infected person develops their own antibodies through post-exposure vaccination. Rabies is a fatal viral disease spread to humans through bites or scratches from infected animals. Over 59,000 people die globally every year due to rabies, mostly in Asia and Africa and the majority of victims are children. There is an urgent need to control rabies virus transmission and promote effective post-exposure prophylaxis (PEP), which involves timely vaccination and administration of rabies immunoglobulin. The global Rabies Antiserum Market is estimated to be valued at US$ 1.24 Bn in 2023 and is expected to exhibit a CAGR of 3.3% over the forecast period 2023 to 2030, as highlighted in a new report published by Coherent Market Insights. Market Opportunity: The opportunity to effectively treat rabies exposure presents a major market opportunity for rabies antiserum. Rabies kills thousands globally every year mainly in developing regions where healthcare access and immunization rates are low. Timely administration of rabies antiserum after exposure is critical to neutralize the virus before symptoms set in. Moreover, people in rural areas living close to domestic and wild animals are at higher risk of contracting rabies. Expanding medical access and availability of low-cost rabies antiserum products in developing country markets can help save lives and drive the market growth over the forecast period. Porter’s Analysis: Threat of new entrants: The biopharmaceutical industry requires huge R&D investments and navigating an extensive regulatory approval process. This poses high entry barriers for new companies. Bargaining power of buyers: Individual buyers have low bargaining power due to lack of availability of substitutes for rabies antiserum therapy. However, large healthcare institutions can negotiate on price. Bargaining power of suppliers: Few manufacturers globally supply rabies immune globulin and they have significant bargaining power over buyers. However, presence of generic competitors balances out this power.

SWOT Analysis: Strengths: Growing rabies burden globally increases treatment demand. Established treatment protocols ensure stable revenues. Weaknesses: High manufacturing costs and lengthy production cycles limit capacity expansions. Supply disruptions impact patient access. Opportunities: Emerging economies with limited access present an untapped market potential. New formulations/indications can boost growth. Threats: Stringent regulations delay product approvals. Biosimilars/generics capture market share. Substitution with cheaper therapies in price-sensitive regions. Key Takeaways: The global rabies antiserum market is expected to witness high growth due to rising rabies incidence and lack of substitute treatment options. Regional analysis shows Asia Pacific dominating the market currently owing to India being a major production hub. North America also captures significant share due to growing bites from rabid animals. Key players operating in the rabies antiserum market are CSL Behring, Sanofi Pasteur, Grifols S.A., Bharat Serum and Vaccines Ltd., Novartis AG, Kedrion Biopharma Inc., Biogenesis Bago SA, Serum Institute of India Ltd., Haffkine Bio-Pharmaceutical Corporation Ltd., Shanghai Institute of Biological Products Co. Ltd., CNBG (China National Biotec Group) Co. Ltd., Harbin Pharmaceutical Group Co. Ltd., Beijing Tiantan Biological Products Co. Ltd. The Asia Pacific region is projected to grow at the fastest rate during the forecast period led by high unmet needs, increasing patient burden and improving access and awareness.

[tigermike]

In 1986, a 28-year-old man named Neelim Kumar Khaire set a world record for being locked up with 72 of the most venomous snake species found in India for 72 hours. He aimed to raise awareness and educate the public on how snakes do not attack unless provoked.

"Reptiles were frequent visitors at my place in Matheran. I hated killing such beautiful creatures—most of them were harmless. So I started catching and releasing them in the Sahyadri hills. I once caught a snake and took it to the Haffkin Institute in Bombay. I was told that it was poisonous and too risky to be carried in this way. The incident boosted my courage, and so began my obsession with snakes."

After 72 hours, an exhausted Khaire emerged from the cage without a single snake bite.

"I will now be able to set up a trust-run snake park and a research center with the initial funds from the proceeds of the feat. I stalled my parents' efforts to get me married until I fulfilled my ambition of creating a world record. Now I am ready."

True to his word, Khaire went on to establish Katraj Snake Park, which now houses 160 different snake species. His passion for wildlife and animals also motivated him to create the first animal orphanage in India. Today, Khaire continues to work as a zoologist and has published four books about snakes.

[marathinewslive]

"तुम्हाला अंगठाछाप मंत्री दिसतो का?," 'त्या' वक्तव्यावरुन ट्रोल होत असल्याने तानाजी सावंत संतापले | Maharashtra Health Minister Tanaji Sawant on his statement over haffkine sgy 87

“तुम्हाला अंगठाछाप मंत्री दिसतो का?,” ‘त्या’ वक्तव्यावरुन ट्रोल होत असल्याने तानाजी सावंत संतापले | Maharashtra Health Minister Tanaji Sawant on his statement over haffkine sgy 87

राज्याचे आरोग्यमंत्री तानाजी सावंत सध्या आपल्या एका वक्तव्यामुळे चर्चेत आहेत. सोशल मीडियावर तानाजी सावंत यांच्या नावे एक मेसेज व्हायरल होत आहे. यामध्ये तानाजी सावंत यांनी ससून रुग्णालयातील डॉक्टरांना हाफकिन नावाच्या माणसाकडून औषध घेणं बद करा असा सल्ला दिल्याचा दावा आहे. तसंच स्थानिक वृत्तपत्रांमध्येही यासंदर्भात बातम्या प्रसिद्ध झाल्या आहेत. यावरुन तानाजी संताप संतापले असून टीका करणाऱ्यांना उत्तर…

[3media]

Maharashtra: Haffkine fails to find Remdesivir bidder, state to face shortage

Maharashtra: Haffkine fails to find Remdesivir bidder, state to face shortage

#Maharashtra #Haffkine #fails #find #Remdesivir #bidder #state #face #shortage Maharashtra is staring at an acute shortage of Remdesivir across all district government hospitals and medical colleges with Haffkine Biopharma Private Limited, the nodal agency for its procurement in the state, unable to find a bidder to supply the anti-viral drug. With demand high across Madhya Pradesh, Rajasthan,…

[24gnewshindi]

कोवाक्सिन का उत्पादन मई-जून तक दोगुना हो सकता है, सितंबर तक प्रति माह 10 Cr खुराक

कोवाक्सिन का उत्पादन मई-जून तक दोगुना हो सकता है, सितंबर तक प्रति माह 10 Cr खुराक

नई दिल्ली: सरकार ने शुक्रवार को कहा कि स्वदेशी रूप से विकसित कोवाक्सिन वैक्सीन की वर्तमान उत्पादन क्षमता मई-जून तक दोग���नी हो जाएगी और फिर जुलाई – अगस्त तक लगभग छह से सात गुना बढ़ जाएगी, यह सितंबर तक प्रति माह लगभग 10 करोड़ खुराक तक पहुंचने की उम्मीद है। विज्ञान और प्रौद्योगिकी मंत्रालय ने एक आधिकारिक विज्ञप्ति में कहा कि मिशन COVID सुरक्षा की घोषणा सरकार ने Atmanirbhar Bharat 3.0 के तहत स्वदेशी…

[i-was-today-years-old-when]

i learned that in 1896, a bubоnіc plаgue epіdеmic struck Bombay, and the government asked Waldemar Haffkine, developer of the first chоlera vаccіne, to help. After 3 months of persistent work (1 assistant had a nervous breakdown and 2 others quit), a vаccіne was ready, with Haffkine tеsting it on himself first (x)

[big-fan-10]

Bubonic Plague 1896-1903

Now we have the Bubonic Plague, also known as the Black Death back in the Mid-Thirteen Hundreds. I shall be talking about the instance in the late 19th Century that lasted into the Early 20th Century, specifically the system used in British Ruled India to handle it,,, and how the people of India responded.

To start off India at the time was under the rule of a British government because of colonisation, so you can except sentiment towards the British to be poor, which definitely had an impact on how governments attempt to handle the spread of the Bubonic Plague was received. In the year 1896 because of rats bitten by infected fleas on board trade vessels coming from China the Bubonic Plague spread through India, starting from the Port Cities, moving inland from the the bite of infected rats which could get into granaries, and contact with infected carcasses.The estimated loss of life in India was at least 3 times greater the the overall 3 Million lives ended because of the plague all over the world, this loss of life can be placed on two things, one the British Government in charge of India not being willing to effect global trade, and the relationship between the people of India and British, as the British believed the outbreak was simply a result of the their lifestyles.

After his success with creating a vaccine for Cholera Dr, Waldemar Haffkine while working for the British Government was commissioned to deal with the Bubonic Plague, and using the incarcerates of a Bombay Jail along with himself as the test subjects was able to successfully create a working inoculation to deal with the Plague. Sadly sentiment between the Government and people prevented the vaccination efforts from being successful, however things would end up getting worse. 

So we have our first two similarities to the current situation, first of all desire from people not to risk global trade, and the economy despite risk to human life, and second the sentiment between the people, their government, and medical professionals is negative, which leads to people, for Canada a minority ignoring and avoiding any proof that both the health crisis is real, that the government has an actual reason for it’s actions, and that the inoculation is safe.

Now in order to prevent the virus from spreading out of control a special piece of legislation was made official in 1897 and still is in effect to this day, this was the Epidemic Diseases Act, the reason this made things worse for the relationship between the Government and people is that in order to deal with the outbreak it gave Officials the ability to take measures that were viewed as intrusive, The powers afforded to health officials were; a requirement for travellers to prove they had been vaccinated, the ability to remove infected from there homes and isolate them from the populace, control evacuations, recruit the aid of the Military and Police in going about their duties, demolition of infested housing, perform disinfection, even performing inspections of transport leading to the removal and detention of infected citizens. Among the procedures implemented to make regulation easier was the division of areas into villages overseen by a deputy commissioner, assistant deputy commissioner, division officer, civil surgeon and medical officer, alongside support personal. This lead to concern from the populace about the Government trying to control them, and in some areas riots which were handled by the army to allow for proper enforcement,,, until things reached a point where proper enforcement became impossible.

The big issues that ended up preventing proper enforcement was that there were more people travelling all over the country in order to escape Government notice then the officials working to handle the pandemic, next came the riots, people actively hiding the infected strikes and mass shop closures grinding the economy to a halt. This forced the Government to change there approach as the Military was withdrawn, and the Vaccine Passport System which had been used with lax enforcement or ineffective enforcement was now fully unenforced. It just came down to trying to limit the spread of the disease and have a riot on their hands with a shut down economy, or prevent sentiment between the people and government from getting any worse while keeping vaccination efforts as passive as possible. Sadly this meant that this instance of the Bubonic Plague would not be ended until 1903, a whole 7 years later. 

Next time I’ll be going over vaccination efforts in regards to the Smallpox outbreak in the US during the 19th Century. 

https://www.livemint.com/mint-lounge/features/when-the-1897-bubonic-plague-ravaged-india-11587876174403.html

https://www.ctvnews.ca/health/coronavirus/the-vaccine-passport-debate-isn-t-new-it-started-in-1897-during-a-plague-pandemic-1.5388211

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763662/

https://www.cbc.ca/news/canada/newfoundland-labrador/apocalypse-then-vaccine-passports-1.6114663

[adelicateculturecell]

"Holospora were first described by Waldemar Haffkine in 1890. He'd been studying Paramecium caudatum when he noticed these parasitic organisms residing in the nucleus. Through his investigation, Haffkine would end up identifying three species: Holospora obtusa, Holospora undulata, and Holospora elegans."

Journey to the Microcosmos- Our Paramecia Are Infected

Images originally captured by Jam’s Germs