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Genomics Market - Forecast(2024 - 2030)
Global Genomic Market Overview:
A genome is the genetic material of an organism. It includes both the genes and the noncoding DNA, as well as mitochondrial DNA and chloroplast DNA. The study of genomes is called genomics. The genomics market is gaining traction owing to its applications in various fields of study such as intragenomic phenomenon including epistasis, pleiotropy, heterosis, and other interactions between loci and alleles within the genome. In this era of medical and life science innovations shaping itself as an inevitable uptake for sustainability of mankind, the genomic research is poised for exponential growth owing to imperative genetic innovations feeding off it. Abundant potential has driven this arcade to reach a staggering market size of $16 billion - $16.5 billion as of 2018, and the demand is estimated to increment at formidable CAGR of 9.2% to 10.2% during the forecast period of 2019 to 2025.
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Global Genomic Market Outlook:
Genomics is extensively employed in healthcare, agriculture, biotechnology, DNA sequencing, and diagnostics. In the healthcare segment, genomics is used for the development of vaccines and drugs. This segment leads the application vertical and is growing with a CAGR of 10.1%-10.7 % through to 2025. Genomics plays a significant part in diagnosis of several genetic disorders. It has an ample scope in personalized medication as it can advocate a medical management constructed on the genetic face of a person with the help of clinical data and AI. It is also applied in synthetic biology and bioengineering. Genomics research in agriculture is hired for plant breeding and genetics to cultivate crop production. The understanding of gene function and the accessibility of genomic maps along with an enhanced understanding of genetic variant will aid the plant breeders to identify the traits and then manipulate those traits to obtain a high yield. All these factors affecting the enormous medical and agricultural sector are all set to stroke the genomics market with abundant demand.
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Global Genomic Market Growth Drivers:
As per the National Center for Biotechnology Information, U.S, the progression in oncology (study and treatment of tumor) expenses is forecast to rise 7%â10%âannually throughout 2020, with universal oncology cost exceeding $150âbillion[1]. As per the WHO, cancer is a leading cause of death worldwide, accounting for an estimated 9.6 million deaths in 2018[2]. And the total annual economic cost of cancer at the initial period of this decade was estimated at approximately $1.16 trillion. Thus the application of genomics in exploring cell-free circulating DNA by several R&D sectors as a potential biomarker for cancers is driving the market towards exponential growth. The genomics market with its current potential displays all the necessary traits it can adapt in the coming years to divert a huge chunk of traffic and revenue from the omnipresent cancer diagnostics.
As per the Food and Agriculture Organization of United Nations, between 1960 and 1990 the arable land increased by 1.5 billion ha, and in the recent past decades the elevation recorded is just 155 million ha[3]. With decreasing arable floor and the increasing global population augmenting the demand for food by 70% (by 2050), obtaining a high yield is a major trend in the agricultural sector. Genomics market is all set to capitalize on this unprecedented demand scenario. Genomics supplements the understanding of gene function and the accessibility of genomic maps along with an enhanced understanding of genetic variant, thus aiding the plant breeders to identify the traits and then manipulate those traits to obtain a high yield.
After an acute analysis of the regional insights of the global genomics market, North America is revealed to hold 39% to 40% of the entire global market size as of 2018. Such dominance can be attributed to several aspects such as cumulative investment on research by federal administrations, growing patient awareness, and accessibility of urbane healthcare facilities.
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Global Genomics Market Players Perspective:
Some of other key players profiled in this IndustryARC business intelligence report are Beckton Dickson, Synthetic Genomics Inc. (SGI) ,Cepheid, Inc., Affymetrix, Inc., Bio-Rad Laboratories, Inc., Agilent Technologies, GE Healthcare, Illumina, Inc., Danaher Corporation,F. Hoffmann-La Roche, QIAGEN, Thermo Fisher Scientific and PacBio (Pacific Biosciences of California). Majority of the companies mentioned are situated in North America augmenting the regional affluence in the global market.
Global Genomics Market Trends:
High overload owing to a wide range of reagents and consumables has propelled companies into approving different policies to endure in the market and stay ahead of the curve.
For instance, in January 2017, BD launched Precise WTA Reagents for precise and guileless quantification of hereditary data form single cell analysis. Moreover, in July 2016, SGI-DNA entered into a distribution agreement with VWR International, an American company involved in the distribution of research laboratory products, with over 1,200,000 items to more than 250,000 customers in North America and Europe.
Genomics Market Research Scope
The base year of the study is 2018, with forecast done up to 2025. The study presents a thorough analysis of the competitive landscape, taking into account the market shares of the leading companies. It also provides information on unit shipments. These provide the key market participants with the necessary business intelligence and help them understand the future of the Genomics Market. The assessment includes the forecast, an overview of the competitive structure, the market shares of the competitors, as well as the market trends, market demands, market drivers, market challenges, and product analysis. The market drivers and restraints have been assessed to fathom their impact over the forecast period. This report further identifies the key opportunities for growth while also detailing the key challenges and possible threats. The key areas of focus include the types of equipment in the Genomics Market, and their specific applications in different phases of industrial operations.
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Genomics Market Report: Industry Coverage
Types of Solutions Genomics Market:
By Product Types-Â Microarray chip, Sequencers.
By Application-Â Genotyping, SNP analysis.
By End-User-Â Anthropology, Diagnostics.
The Genomics Market report also analyzes the major geographic regions for the market as well as the major countries for the market in these regions. The regions and countries covered in the study include:
North America: The U.S., Canada, Mexico
South America: Brazil, Venezuela, Argentina, Ecuador, Peru, Colombia, Costa Rica
Europe: The U.K., Germany, Italy, France, The Netherlands, Belgium, Spain, Denmark
APAC: China, Japan, Australia, South Korea, India, Taiwan, Malaysia, Hong Kong
Middle East and Africa: Israel, South Africa, Saudi Arabia
#genomics#genomics market#genomics market size#genomics market share#genomics market value#genomics market report#DNA microarrays#Electrophoresis#X-Ray Crystallography#Polymerase Chain Reaction#DNA Sequencers#Chromatography#Bio-informatics Tools#Bio-informatics Database#DNA Sample Sequencing#SNPS Analysis#Molecular Biology#Gene Expression Analysis#Genotyping#Targeted Re-sequencing#Individual Genome Sequencing#Biomarker Solutions
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Explore the dynamic landscape of the Genomics market, where cutting-edge technologies converge with healthcare innovation to unlock the mysteries of our genetic blueprint.
#Genomics Market#Genomics Industry#Genomics Market size#Genomics Market share#Genomics Market demands#Genomics Market trends#Genomics Market growth#Genomics Market report
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#Global Spatial Genomics and Transcriptomics Market#Global Market#Market News#Market Research Reports
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The Artificial Intelligence in Genomics Market in genomics in 2023 is US$ 0.71 billion, and is expected to reach US$ 14.91 billion by 2031 at a CAGR of 46.2%.
#Artificial Intelligence in Genomics Market#Artificial Intelligence in Genomics Market Scope#Artificial Intelligence in Genomics Market Report
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Latest Advances in Gene and Cell Therapies Transform Healthcare
Gene and cell therapies represent a ground-breaking advancement in medical science, offering potential cures for a variety of previously untreatable diseases. These therapies are revolutionizing how we provide targeted healthcare by modifying genetic material or using cells to restore or alter biological functions. Early interventions in congenital disorders can significantly reduce long-term health complications, offering a healthier start to life for newborns. Thus, the potential of gene and cell therapies to transform medical treatments is immense, especially in the field of natal and prenatal care.
A notable example of gene therapy involved the birth of the first babies with edited genes. In 2018, Dr. Jiankui announced the birth of twin girls whose genes were edited using CRISPR technology. He edited and deactivated a gene known as CCR5Â with the goal of conferring resistance to HIV in those girls.
Latest Developments in Gene and Cell Therapies
The field of gene and cell therapies is crucial in the mainstream as drug-regulating authorities approve treatments for diseases like lymphoma and muscular dystrophy. Let us explore the latest developments regarding these therapies.
Non-Hodgkin lymphoma (NHL) accounts for about 4% of all cancers in the US, with an estimated 80,620 new cases expected this year. In this regard, Bristol Myers Squibbâs Breyanzi, a CAR T cell therapy, was approved in 2024 by the FDA, which utilizes the patientâs immune system to target and destroy cancer cells.
In 2024, the FDA approved Sarepta Therapeuticsâ Elevidys, a gene therapy for Duchenne muscular dystrophy (DMD), which affects approximately 1 in 3,500Â to 5000Â male births worldwide, typically manifesting between ages 3 and 6. This groundbreaking offers new hope by addressing the root cause of this debilitating condition.
Exploring Current and Future Applications
CRISPR and Genome Editing: CRISPR technology has revolutionized genome editing, offering precise modifications to DNA and correcting genetic defects at their source. This technology is being explored for a variety of applications including current and future applications. However, acquiring approvals to run trials on humans has always been challenging, yet the CTX001Â stands out with its success in this regard. The CTX001 is an autologous gene-edited stem cell therapy developed by CRISPR Therapeutics and Vertex Pharmaceuticals.
Dr. Haydar Frangoul, the medical director at HCA Sarah Cannon Research Institute Center, has been treating the first patient in the CTX001 trial for SCD therapy. The patient had battled sickle cell disease for 34 years before undergoing this one-time treatment. Post-treatment, her blood showed a significant proportion of fetal hemoglobin levels, enabling her to avoid blood transfusions and pain attacks without major side effects.
Stem Cell Research: These cells have the unique ability to differentiate into various cell types, making them invaluable for regenerative medicine. Research in stem cell therapy aims to treat conditions such as Parkinsonâs disease, diabetes, and spinal cord injuries by replacing damaged cells with healthy ones in the near future. A notable example is a study using device-encapsulated pancreatic precursor cells derived from human embryonic stem cells. This study has shown that increased cell doses in optimized devices lead to detectable insulin production and improved glucose control.
CAR-T Cell Therapy: This therapy has shown impressive results in treating certain types of leukemia and lymphoma, offering hope for patients who have not responded to traditional treatments. This innovative approach uses modified T-cells to target and kill cancer cells. The future of CAR-T therapy looks promising, thereby expanding its application to treat more types of cancers, including solid tumors.
Gene Silencing and RNA-based Therapies: Emerging technologies like RNA interference (RNAi) and antisense oligonucleotides (ASOs) are being developed to silence harmful genes. An RNAi therapy like âAMVUTTRAâ developed by Alnylam, is approved in the US for treating polyneuropathy of hereditary transthyretin-mediated (hATTR) amyloidosis in adults. Thus, the future use of RNA therapies includes the treatment of neurodegenerative diseases like Huntingtonâs disease.
Understanding Ethical Considerations & the Role of Regulatory Bodies
Ethical frameworks must evolve amidst the concerns regarding âdesigner babiesâ, where genetic modifications used to select desired traits pose significant ethical dilemmas. A prominent example is the controversy of using CRISPR technology in human embryos, who claimed to have created the first gene-edited babies, sparking ethical debates and leading to his imprisonment. Several studies emphasize the importance of international regulatory standards and effective governance to ensure the responsible use of gene editing technologies.
Amidst the rapid pace of technological advancement, regulating gene and cell therapies needs rigorous safety standards. The regulatory bodies and agencies like the FDAâs Center for Biologics Evaluation and Research (CBER) in the US and the European Medicines Agency (EMA) in the EU play a critical role. Their frameworks include guidelines for approval of regenerative medicines and conditional or time-limited authorizations to facilitate quicker access to innovative treatments.
What the future beholds?
The future of gene and cell therapies lies in their integration into personalized medicine based on the genetic makeup of individual patients. Companies like CRISPR Therapeutics, Editas Medicine, and Intellia Therapeutics are at the forefront of research, developing therapies that could revolutionize the treatment of genetic disorders. As these therapies become more refined and accessible, they could significantly extend healthy life spans and improve the quality of life for millions.
#Gene and Cell Therapies#healthcare#lifesciences#genome editing#CRISPR technology#Stem Cell therapy#triton market research#market research reports
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The Asia-Pacific genomic cancer panel and profiling market was valued at $1.56 billion in 2023 and is expected to reach $4.78 billion by 2033, growing at a CAGR of 11.81% between 2023 and 2033.
#APAC Genomic Cancer Panel and Profiling Market#APAC Genomic Cancer Panel and Profiling Report#APAC Genomic Cancer Panel and Profiling Industry#Healthcare and Medical#BISResearch
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https://heyjinni.com/read-blog/51380_genomics-and-proteomics-reagents-research-kits-and-analytical-instruments-market.html
Genomics And Proteomics Reagents, Research Kits And Analytical Instruments Market Size, Overview, Share and Forecast 2031
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Unlocking the Future of Cancer Diagnosis: Genomic Cancer Panel and Profiling Market Insights
ntroduction: Cancer, a complex and multifaceted group of diseases, continues to challenge the healthcare industry. However, advancements in genomics have opened new doors for personalized and targeted cancer treatments. One of the groundbreaking tools in this field is the Genomic Cancer Panel and Profiling market. In this blog, we'll delve into the key aspects of this market and explore how it is revolutionizing cancer diagnosis and treatment strategies.
Understanding Genomic Cancer Panel and Profiling:
Genomic cancer panel and profiling involve the comprehensive analysis of a patient's DNA, RNA, and other molecular markers to understand the genetic alterations driving cancer growth. This approach provides a detailed molecular profile of the tumor, allowing healthcare professionals to tailor treatment plans based on the unique genetic makeup of each patient's cancer.
Market Value observed in 2022 was $ 9.90 Billion, and the CAGR in 2023-2032 was found out to be 9.43%.Â
Market Growth and Trends:
The genomic cancer panel and profiling market have witnessed significant growth in recent years, driven by increasing cancer incidence, technological advancements, and a growing understanding of the role of genetics in cancer development. The market is characterized by a surge in collaborations between biotechnology companies, academic institutions, and healthcare providers to enhance research capabilities and develop innovative solutions.
Key Players and Technologies:
Several key players dominate the genomic cancer panel and profiling market, offering cutting-edge technologies and solutions. Illumina, Thermo Fisher Scientific, and QIAGEN are among the prominent companies leading the way in developing sequencing platforms and analysis tools. Next-generation sequencing (NGS) technologies play a pivotal role, enabling high-throughput and cost-effective analysis of large genomic datasets.
Clinical Applications:
The clinical applications of genomic cancer panel and profiling are diverse and impactful. These include identifying potential therapeutic targets, predicting treatment response, and uncovering resistance mechanisms. Additionally, this approach aids in the early detection of hereditary cancer syndromes, facilitating preventive measures for at-risk individuals.
Challenges and Opportunities:
While the genomic cancer panel and profiling market hold immense promise, it is not without challenges. Data interpretation, standardization of testing protocols, and the integration of genomic information into clinical practice pose ongoing hurdles. However, these challenges also present opportunities for further research, technological innovation, and collaboration to overcome barriers and improve patient outcomes.
Future Prospects:
The future of genomic cancer panels and profiling looks promising, with ongoing advancements in artificial intelligence, machine learning, and data analytics enhancing our ability to extract meaningful insights from vast genomic datasets. Integrating these technologies into routine clinical practice could streamline decision-making processes, optimize treatment strategies, and contribute to the broader field of precision medicine.
Conclusion:
The Genomic Cancer Panel and Profiling market are at the forefront of transforming cancer care by providing personalized and targeted approaches to diagnosis and treatment. As we continue to unlock the mysteries of the human genome, the synergy between technology, research, and clinical application holds the key to a future where cancer is not just treated but understood at its genetic core, paving the way for more effective and tailored therapies.
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USA Genome Sequencing Market- A Story of Rapid Development
According to MarkNtel Advisorsâ research report titled âUSA Genome Sequencing Market Analysis, 2020â, the USA Genome Sequencing market is anticipated to grow at a considerable CAGR during 2020-25F on an account of bolstering investment in genomics medicine and rising partnerships among the market players to accelerate the adoption of genomics in order to support the increasing demand for clinical grade genomic information at lower cost.
#USA Genome Sequencing Market Growth#USA Genome Sequencing Market Report#USA Genome Sequencing Market Size#USA Genome Sequencing Market Share
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Genomic Testing for Cancer: Improving Treatment and Diagnosis
The field of genomics is revolutionizing how people perceive cancer. Clinicians are using it to diagnose drug resistance in patients and give them precise oncology treatments. Additionally, the use of cancer genomes could facilitate early diagnosis and forecast treatment failures. In the end, utilizing genomics in cancer treatment will significantly enhance patient outcomes and increase the treatability of this lethal group of diseases.
A growing number of sophisticated and reliable genetic testing techniques have been developed as a result of the rapid advancement of genomic technologies. Thus, it is anticipated to drive the market growth. In addition, according to a research report by Astute Analytica, the global genomic testing market is likely to grow at a compound annual growth rate (CAGR) of 9.54% over the projection period from 2023 to 2031.
How can cancer genomics enhance diagnosis?
National screening initiatives, which mostly include physical exams and medical imaging, continue to play a significant role in the diagnosis of cancer. After a tumor is found, a biopsy is performed to assist with the diagnosis. The tissue is subjected to molecular testing for cancer-specific biomarkers, and the genetic data obtained is then utilized to select medicines and track the outcomes of treatment.
However, due to the position of the tumor, the biopsy technique is occasionally challenging and frequently uncomfortable for the patient. Additionally, some individuals still do not exhibit a sustained response or do not respond at all after being matched to a therapy. In essence, many cancer treatments are useless, and regrettably, this is frequently difficult to ascertain immediately away. As a result, significant research has been done to enhance the cancer diagnostic process using genomics and other molecular technologies.
How can cancer genomics improve available treatments?
Personalized oncology
Targeted therapies that are tailored to the genetic causes of cancer have been created since the introduction of genomic sequencing. Precision oncology refers to the delivery of personalized cancer care based on the genetic and molecular characteristics of a particular patient's cancer.
When determining which medicine is best for a patient, the practice also takes into account their epigenome, proteome, lifestyle, microbiome, and food. At different stages of precision oncology, understanding cancer genetics is essential to successfully administering targeted therapies. This might come from patient management procedures as well as clinical trials.
Rediscovering of drugs
Large-scale genetic profiling of tumors not only allows for the identification of potential therapeutic molecular variants linked to licensed anticancer medications. It also aids in the identification of variants that may be handled differently from those that are now available and more conventional. A trial with an adaptive design known as the Drug Rediscovery Protocol was started in 2016 to find signs of activity in cancer patients receiving treatment with medications that were not prescribed according to the drug's approved label.
The goal of the study was to gather and disseminate for the first time systematically the successes and failures of these non-traditional medicines. Treatment options can be challenging since tumors can contain numerous driver mutations and are quite complex.
Content Source: - Genomic Testing Market
#business#healthcare#health#Genomic Testing#Genomic Testing Market#Cancer Genomics#Diagnosis#treatment plan#market report#market research#Astute Analytica
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#Genome Editing Market#Genome Editing Market Trends#Genome Editing Market Growth#Genome Editing Market Industry#Genome Editing Market Research#Genome Editing Market Reports
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The next pandemic is inevitable. Australia isnât ready - Published Sept 23, 2024
(Before you Americans yell at me, It's already the 23rd in Australia. This is very late-breaking)
I thought this was a really good breakdown of the current situation given the government-approved covid denial we live in. Long, but worth a read.
By Kate Aubusson and Mary Ward
Top infectious disease and public health veterans at the nerve centre of the stateâs war against COVID-19 are sounding the alarm.
NSW is less prepared today to fend off a deadly pandemic despite the lessons of COVID-19, say top infectious disease and public health veterans at the nerve centre of the stateâs war against the virus.
And we wonât have another hundred years to wait.
NSWâs gold standard Test-Trace-Isolate-Quarantine and vaccination strategies will be useless if a distrusting population rejects directives, refuses to give up its freedoms again, and the goodwill of shell-shocked public health workers dries up.
A panel of experts convened by The Sydney Morning Herald called for a pandemic combat agency akin to the armed forces or fire brigades to commit to greater transparency or risk being caught off guard by the next virulent pathogen and misinformation with the potential to spread faster than any virus.
âItâs inevitable,â says Professor Eddie Holmes of the next pandemic. A world-leading authority on the emergence of infectious diseases at the University of Sydney, Holmes predicts: âWeâll have less than 100 years [before the next pandemic].
âWeâre seeing a lot of new coronaviruses that are spilling over into animals that humans are interacting with,â said Holmes, the first person to publish the coronavirus genome sequence for the world to see.
âPeople are exposed all the time, and each time we are rolling the dice.â
The independent review of NSW Healthâs response to COVID-19 opened with the same warning: âNo health system or community will have the luxury of 100 years of downtime.â
Pandemic preparedness needs to be a âpermanent priorityâ, wrote the reportâs author, Robyn Kruk, a former NSW Health secretary, ârather than following the path of those that have adopted a âpanic and forget strategy,â allowing system preparedness to waneâ.
Why we donât have 100 years to wait for the next pandemic The World Health Organisation has declared seven public health emergencies of international concern since 2014, including the current mpox outbreak.
Climate change is turbocharging the factors that coalesce to create the perfect breeding ground for a pandemic-causing virus, including population increases, bigger cities, and better-connected global markets and migration.
âAnimals will be forced into more constrained environments, and humans that rely on those environments will be again constrained in the same environments. There will be more wet markets, more live animal trade that will just increase exposure,â Holmes said.
âIt was clear that we werenât ready [for COVID],â said Jennie Musto, who, after seven years working for the World Health Organisation overseas, became NSW Healthâs operations manager for the Public Health Emergency Operations Centre, the team responsible for NSWâs COVID-19 contact tracing and containment.
âEveryone had preparedness plans gathering dust on a shelf, but no one was actually ready to respond, and so everyone was on the back foot,â Musto said. âPerhaps none of us really thought this was going to happen. We were waiting 500 years.â
Who would willingly become the next doomed whistleblower? Eddie Holmes, known for his repeated assertion that SARS-CoV-2 did not come from a lab, is deeply concerned that when the next pandemic-causing virus emerges, chances are it will be covered up.
âMy worry is that if the virus appeared in a small population, say, somewhere in Southeast Asia, the people involved wouldnât blow the whistle now, given the fact that you would get blamed,â he said.
Li Wenliang, the Wuhan doctor who tried to raise the alarm about a virulent new virus, was reportedly reprimanded by police for spreading rumours and later died of COVID-19.
The global blame game, culminating in a deep distrust of China and accusations that the virus was grown in a Wuhan lab, is why Holmes believes âweâre in no better place than we were before COVID started, if not worseâ.
âI work with a lot of people in China trying to keep the lines of communication open, and theyâre scared, I think, or nervous about saying things that are perceived to counter national interest.â
From a vaccine perspective, our defences look strong. There have been monumental advancements in vaccine development globally, driven by mRNA technology. In Sydney this month, construction began on an RNA vaccine research and manufacturing facility.
âBut the way I see it is that nothing has been done in terms of animal surveillance of outbreaks or data sharing. The [global] politics has got much, much worse,â Holmes said.
Combat force Conjoint Associate Professor Craig Dalton, a leading public health physician and clinical epidemiologist, called for a dramatic expansion of the public health workforce and the establishment of a pandemic combat force that would routinely run real-time pandemic simulations during âpeacetimeâ.
âNo one is upset with fire brigades spending most of the time not fighting fires. They train. A lot. And thatâs probably how we need to move,â he said.
âWe need exercise training units so that every major player in pandemic response is involved in a real-time, three to four-day pandemic response every three to five years at national, state and local [levels].â
The federal Department of Health and Aged Care recently ran a health emergency exercise focused on governance arrangements involving chief health officers and senior health emergency management officials, a spokeswoman for Health Minister Mark Butler said. The outcomes of this exercise will be tested later this year.
Dalton said desktop simulations and high-level exercises involving a handful of chiefs didnât cut it, considering the thousands of people working across regions and states. He instead suggested an intensive training program run in the Hunter New England region before the 2009 H1N1 pandemic provided a good model.
âWe were ringing people, actors were getting injections, just like a real pandemic,â said Dalton, who once ordered a burrito in a last-ditch effort to contact a restaurant exposed to COVID-19.
Our heroes have had it The expert panel was emphatic that our pandemic response cannot once again rely on the goodwill of the public health and healthcare workforce.
According to the Kruk review, what began as an emergency response ultimately morphed from a sprint into an ultra marathon and âan admirable (yet unsustainable) âwhatever it takesâ mindsetâ.
They were hailed as heroes, but the toll of COVID-19 on healthcare workers was brutal. Workloads were untenable, the risk of transmission was constant, and the risk of violence and aggression (for simply wearing their scrubs on public transport in some cases) was terrifying.
âWe got through this pandemic through a lot of people working ridiculous hours,â Dalton said.
âYou talk to a lot of people who did that and say they could not do it again.â
Tellingly, several expert personnel who worked at the front lines or in the control centre of NSWâs pandemic defences were invited to join the Heraldâs forum but declined. Revisiting this period of intense public scrutiny, culminating in online attacks and physical threats, was just too painful.
So long, solidarity Arguably, the biggest threat to our pandemic defences will be the absence of our greatest strength during COVID: the populationâs solidarity and willingness to follow public health orders even when it meant forfeiting fundamental freedoms.
The public largely complied with statewide public health orders, including the stay-at-home directive that became the 107-day Delta lockdown, and other severe restrictions prevented many from being at the bedside of their dying loved ones, visiting relatives in aged care homes and attending funerals.
âMy worry is that next time around when those sorts of rules come out, people may say, âWell, donât worry about it.â They relax it in the future. Why donât we just not stick to the rules?â said Professor Nicholas Wood, associate director of clinical research and services at the National Centre for Immunisation Research and Surveillance.
âIâm not sure we quite understand whether people [will be] happy with those rules again,â he said.
Dalton was more strident.
âI tend to agree with Michael Osterholm ⊠an eminent US epidemiologist [who] recently said the US is probably less prepared for a pandemic now than it was in 2019, mostly because the learnings by health departments in the COVID pandemic may not make a material difference if faced with a community that distrusts its public health agencies,â he said.
âIf H1N1 or something else were to spill over in the next couple of years, things like masks, social distancing and lockdowns would not be acceptable. Vaccination would be rejected by a huge part of the population, and politicians might be shy about putting mandates in.â
As for the total shutdown of major industries, people will struggle to accept it unless the next pandemic poses a greater threat than COVID, said UNSW applied mathematician Professor James Wood.
The risk of the virus to individuals and their families will be weighed against the negative effects of restrictions, which are much better understood today, said Wood, whose modelling of the impact of cases and vaccination rates was used by NSW Health.
âSomething like school closure would be a much tougher argument with a similar pathogen,â he said.
A previous panel of education experts convened by the Herald to interrogate pandemic decision-making in that sector was highly critical of the decision to close schools for months during NSWâs Delta lockdown.
Greg Dore, professor of infectious diseases and epidemiology at the Kirby Institute, said the publicâs reluctance to adhere to restrictions again may, in part, be appropriate.
âSome of the restrictions on people leaving the country were a bit feudal and too punitive,â he said. âOther restrictions were plain stupid, [for instance] limitations on time exercising outside.â
Meanwhile, the delays to publicly recognise the benefits of face masks and the threat of airborne transmission âate away at trustâ, Dalton said.
âWe shouldnât make those mistakes again,â he said.
Transparent transgressions Uncertainty is not something politicians are adept at communicating, but uncertainty is the only constant during a pandemic of a novel virus.
Vaccines that offered potent protection against early iterations of the COVID virus were less effective against Omicron variants.
â[The public], unfortunately, got hit by a rapid sequence of changes of what was âtrueâ in the pandemic,â James Wood said.
Political distrust can be deadly if governments give the public reason to suspect they are obfuscating.
The expert panel urged NSWâs political leaders to be far more transparent about the public health advice they were given before unilaterally enforcing restrictions.
There was a clear line between public health advice and political decision-making in Victoria. The Victorian chief health officerâs written advice was routinely published online.
In NSW, that line was blurred as Chief Health Officer Kerry Chant stood beside political leaders, most notably former premier Gladys Berejiklian, at the daily press conferences.
Public health experts said that they looked for subtle cues to determine the distinction between the expert advice and the political messaging during press conferences, paying attention to body language, who spoke when and who stayed silent.
âIt is fine for public health personnel to have a different view to politicians. They have different jobs. What is not OK is to have politicians saying they are acting on public health advice [when they are not],â he said.
The âwhysâ behind the decisions being made were missing from the daily press conferences, which created âa vacuum for misinformationâ, said social scientist and public health expert Professor Julie Leask at the University of Sydney.
âThe communication about what you need to do came out, and it was pretty good ⊠but the âwhy weâre doing thisâ and âwhat trade-offs weâve consideredâ and âwhat dilemmas weâve faced in making this decisionâ; that was not shared,â Leask said.
The infodemic In the absence of transparency, misinformation and disinformation fill the vacuum.
âWe had an âinfodemicâ during the pandemic,â said Dr Jocelyne Basseal, who worked on the COVID-19 response for WHO in the Western Pacific and leads strategic development at the Sydney Infectious Diseases Institute, University of Sydney.
âThe public has been so confused. Where do we go for trusted information [when] everyone can now write absolutely anything, whether on Twitter [now called X] or [elsewhere] on the web?â Basseal said.
A systematic review conducted by WHO found misinformation on social media accounted for up to 51 per cent of posts about vaccines, 29 per cent of posts about COVID-19 and 60 per cent of posts about pandemics.
Bassealâs teenage children recently asked whether they were going into lockdown after TikTok videos about the mpox outbreak.
âThere is a lot of work to be done now, in âpeacetimeâ ⊠to get ahead of misinformation,â Basseal said, including fortifying relationships with community groups and teaching scientists â trusted and credible sources of information â how to work with media.
In addition to the Kruk reviewâs six recommendations to improve its pandemic preparedness, NSW Health undertook a second inquiry into its public health response to COVID-19, which made 104 recommendations.
NSW Health Minister Ryan Park said: âWe are working hard to ensure the findings and recommendations from those reports are being implemented as quickly as possible.â
The expert panellists spoke in their capacity as academics and not on behalf of NSW Health or WHO.
The âAs One Systemâ review into NSW Healthâs COVID-19 response made six recommendations 1. Make governance and decision-making structures clearer, inclusive, and more widely understood 2. Strengthen co-ordination, communication, engagement, and collaboration 3. Enhance the speed, transparency, accuracy, and practicality of data and information sharing 4. Prioritise the needs of vulnerable people and communities most at risk, impacted and in need from day one 5. Put communities at the centre of emergency governance, planning, preparedness, and response 6. Recognise, develop and sustain workforce health, wellbeing, capability and agility.
#mask up#covid#covid 19#pandemic#wear a mask#public health#coronavirus#sars cov 2#still coviding#wear a respirator
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Strange Chinese trade-war recommendations at US Congress
COMPREHENSIVE LIST OF THE COMMISSIONâS 2024 RECOMMENDATIONS Part II: Technology and Consumer Product Opportunities and Risks Chapter 3: U.S.-China Competition in Emerging Technologies The Commission recommends:
Congress establish and fund a Manhattan Project-like program dedicated to racing to and acquiring an Artificial General Intelligence (AGI) capability. AGI is generally defined as systems that are as good as or better than human capabilities across all cognitive domains and would surpass the sharpest human minds at every task. Among the specific actions the Commission recommends for Congress:
Provide broad multiyear contracting authority to the executive branch and associated funding for leading artificial intelligence, cloud, and data center companies and others to advance the stated policy at a pace and scale consistent with the goal of U.S. AGI leadership; and
Direct the U.S. secretary of defense to provide a Defense Priorities and Allocations System âDX Ratingâ to items in the artificial intelligence ecosystem to ensure this project receives national priority.
Congress consider legislation to:
Require prior approval and ongoing oversight of Chinese involvement in biotechnology companies engaged in operations in the United States, including research or other related transactions. Such approval and oversight operations shall be conducted by the U.S. Department of Health and Human Services in consultation with other appropriate governmental entities. In identifying the involvement of Chinese entities or interests in the U.S. biotechnology sector, Congress should include firms and persons: â Engaged in genomic research; â Evaluating and/or reporting on genetic data, including for medical or therapeutic purposes or ancestral documentation; â Participating in pharmaceutical development; â Involved with U.S. colleges and universities; and â Involved with federal, state, or local governments or agen cies and departments.
Support significant Federal Government investments in biotechnology in the United States and with U.S. entities at every level of the technology development cycle and supply chain, from basic research through product development and market deployment, including investments in intermediate services capacity and equipment manufacturing capacity.
To protect U.S. economic and national security interests, Congress consider legislation to restrict or ban the importation of certain technologies and services controlled by Chinese entities, including:
Autonomous humanoid robots with advanced capabilities of (i) dexterity, (ii) locomotion, and (iii) intelligence; and
Energy infrastructure products that involve remote servicing, maintenance, or monitoring capabilities, such as load balancing and other batteries supporting the electrical grid, batteries used as backup systems for industrial facilities and/ or critical infrastructure, and transformers and associated equipment.
Congress encourage the Administrationâs ongoing rulemaking efforts regarding âconnected vehiclesâ to cover industrial machinery, Internet of Things devices, appliances, and other connected devices produced by Chinese entities or including Chinese technologies that can be accessed, serviced, maintained, or updated remotely or through physical updates.
Congress enact legislation prohibiting granting seats on boards of directors and information rights to China-based investors in strategic technology sectors. Allowing foreign investors to hold seats and observer seats on the boards of U.S. technology start-ups provides them with sensitive strategic information, which could be leveraged to gain competitive advantages. Prohibiting this practice would protect intellectual property and ensure that U.S. technological advances are not compromised. It would also reduce the risk of corporate espionage, safeguarding Americaâs leadership in emerging technologies.
Congress establish that:
The U.S. government will unilaterally or with key interna- tional partners seek to vertically integrate in the develop- ment and commercialization of quantum technology.
Federal Government investments in quantum technology support every level of the technology development cycle and supply chain from basic research through product development and market deployment, including investments in intermediate services capacity.
The Office of Science and Technology Policy, in consultation with appropriate agencies and experts, develop a Quantum Technology Supply Chain Roadmap to ensure that the United States coordinates outbound investment, U.S. critical supply chain assessments, the activities of the Committee on Foreign Investment in the United States (CFIUS), and federally supported research activities to ensure that the United States, along with key allies and partners, will lead in this critical technology and not advance Chinese capabilities and development....
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Dip-Pen Nanolithography Market Companies: Growth, Share, Value, Size, and Insights , Industry Overview and Forecast to 2032
"Dip-Pen Nanolithography Market Size And Forecast by 2032
Global dip-pen nanolithography market size was valued at USD 3.49 billion in 2024 and is projected to reach USD 9.48 billion by 2032, with a CAGR of 13.3% during the forecast period of 2025 to 2032.
The growth trajectory of the Dip-Pen Nanolithography Market is shaped by various drivers, including technological advancements, favorable regulatory frameworks, and increasing investments in research and development. These growth drivers have catalyzed innovation, leading to the development of cutting-edge solutions that address the diverse needs of end-users.
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Which are the top companies operating in the Dip-Pen Nanolithography Market?
The Top 10 Companies in Dip-Pen Nanolithography Marketare prominent players known for their leadership and innovation. These include companies recognized for their strong product offerings and market influence. These companies have built solid reputations through their commitment to quality, customer satisfaction, and staying ahead of industry trends, making them key competitors in the Dip-Pen Nanolithography Market.
**Segments**
- **Product Type**: The Dip-Pen Nanolithography market can be segmented based on product type into dip-pen nanolithography instruments and dip-pen nanolithography probes. - **Application**: In terms of application, the market can be categorized into life sciences, materials science, and semiconductor industries. - **End-User**: The end-user segmentation of the Dip-Pen Nanolithography market includes research institutes, academic institutions, and pharmaceutical companies.
**Market Players**
- **Bruker Corporation**: A prominent player in the Dip-Pen Nanolithography market, Bruker Corporation offers advanced technologies in life science and materials research. - **Nanoink Inc.**: Specializing in nanotechnology applications, Nanoink Inc. provides innovative solutions for precision manufacturing and research purposes. - **Molecular Vista**: Known for its high-resolution imaging systems, Molecular Vista caters to the needs of customers in the nanolithography field. - **SwissLitho AG**: SwissLitho AG focuses on developing cutting-edge nanolithography solutions for various industries including semiconductor and materials science.
The global Dip-Pen Nanolithography market is witnessing significant growth due to the increasing demand for precise patterning at the nanoscale level across different industries. The product type segment, including dip-pen nanolithography instruments and probes, is experiencing a surge in adoption as these tools offer high-resolution capabilities for various applications. In terms of applications, the life sciences sector holds a substantial market share owing to the growing need for advanced research tools in areas such as genomics, proteomics, and drug discovery. The materials science and semiconductor industries are also driving the market growth as they require nanoscale patterning for developing novel materials and devices.
The end-user segmentation of the Dip-Pen Nanolithography market reflects a diverse customer base ranging from research institutes to pharmaceutical companies. Academic institutions play a crucial role in driving innovation and research in nanotechnology, leading to a significant share of the market.The Dip-Pen Nanolithography market is a niche yet rapidly growing sector driven by the demand for high-precision patterning at the nanoscale level across various industries. The market segmentation based on product type highlights two key categories: dip-pen nanolithography instruments and dip-pen nanolithography probes. These instruments and probes are witnessing increased adoption due to their ability to offer exceptional resolution capabilities, making them ideal for applications requiring precise nanoscale patterning.
In terms of application, the Dip-Pen Nanolithography market can be broadly categorized into life sciences, materials science, and semiconductor industries. The life sciences sector stands out as a major market driver, fueled by the need for advanced research tools in genomics, proteomics, and drug discovery. The materials science and semiconductor industries also contribute significantly to the market growth, leveraging nanolithography for developing innovative materials and cutting-edge devices.
The end-user segmentation of the Dip-Pen Nanolithography market reflects a diverse customer base comprising research institutes, academic institutions, and pharmaceutical companies. Research institutes and academic institutions play a pivotal role in driving innovation and technological advancements in nanolithography by conducting groundbreaking research and exploring new applications for the technology. Pharmaceutical companies also contribute to the market growth by utilizing Dip-Pen Nanolithography for drug development and nanomedicine applications.
Bruker Corporation, Nanoink Inc., Molecular Vista, and SwissLitho AG are key players in the Dip-Pen Nanolithography market, each offering unique solutions and technologies to meet the evolving needs of customers across different industries. Bruker Corporation, with its expertise in life sciences and materials research, continues to drive innovation in the field of nanolithography. Nanoink Inc. focuses on nanotechnology applications, providing precision manufacturing solutions for diverse industrial applications. Molecular Vista is renowned for its high-resolution imaging systems, catering to the demands of customers in the nanolithography sector. SwissLitho AG specializes in developing cutting-edge nanolithography solutions for industries such as sem**Market Players**
- Bruker Corporation - Nanoink Inc. - Molecular Vista - SwissLitho AG - Mirkin Research Group (US) - Elsevier B.V. (Netherlands) - Nanotechnology group (India) - ULVAC (Japan) - BOBST (Switzerland) - Brother Industries, Ltd. (Japan) - KOMORI Corporation. (Japan) - Seiko Epson Corporation. (Japan) - SPGPrints B.V. (Netherlands) - Meyer Burger Technology AG (Switzerland) - Methode Electronics. (US) - Konica Minolta Business Solutions India Pvt Ltd. (India) - Koenig & Bauer AG (Germany) - Xerox Corporation. (US) - Canon Inc. (Japan) - SCREEN Holdings Co., Ltd. (Japan)
The Dip-Pen Nanolithography market is witnessing significant growth and is driven by the increasing demand for precise patterning at the nanoscale level across various industries. The market segmentation based on product type into dip-pen nanolithography instruments and dip-pen nanolithography probes showcases the rising adoption of these tools due to their high-resolution capabilities for a wide range of applications. Particularly, the life sciences segment holds a significant market share fueled by the need for advanced research tools in genomics, proteomics, and drug discovery. The materials science and semiconductor industries are also key contributors to market growth as they require nanoscale patterning for developing
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Key Insights from the Global Dip-Pen Nanolithography Market :
Comprehensive Market Overview: The Dip-Pen Nanolithography Market is experiencing robust growth driven by technological advancements and increasing consumer demand.
Industry Trends and Projections: The market is projected to expand at a CAGR of X% over the next five years, with a significant shift towards sustainability.
Emerging Opportunities: Growing demand for innovative products and services presents new business opportunities in niche segments.
Focus on R&D: Companies are investing heavily in research and development to stay ahead in a competitive market landscape.
Leading Player Profiles: Key players include known for their market leadership and innovation.
Market Composition: The market is fragmented, with both large corporations and small enterprises playing vital roles.
Revenue Growth: The market has seen a steady increase in revenue, driven by strong consumer adoption and product diversification.
Commercial Opportunities: Businesses can capitalize on untapped regional markets and technological advancements to gain a competitive edge.
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The Genomics Market in 2023 is US$ 46.2 billion, and is expected to reach US$ 119.55 billion by 2031 at a CAGR of 12.62%.
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"Genetic Mutation Analysis: Unlocking the Secrets of DNA đ§Ź, $11.3 Billion Market by 2034"
Genetic Mutation Analysis Market is dedicated to identifying and characterizing genetic alterations, offering insights into disease mechanisms, diagnosis, and treatment strategies. Utilizing advanced technologies such as Next-Generation Sequencing (NGS), PCR, and microarrays, this market plays a pivotal role in sectors like healthcare, pharmaceuticals, and research, driving innovations in personalized medicine and genomics.
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The market is witnessing robust growth, fueled by the rise of genomics and precision medicine. Oncology leads the market, spurred by the growing prevalence of cancer and the increasing need for targeted therapies. Following closely is the infectious diseases segment, driven by research into viral mutations and the global focus on pandemic preparedness. Regionally, North America dominates the market, supported by strong investments in biotechnology and a well-established healthcare infrastructure. Europe is the second-highest performing region, benefiting from governmental support for genomic research. The United States stands at the forefront, with its advanced technological capabilities and significant research funding. Meanwhile, China is rapidly emerging, bolstered by government initiatives and growing investments in healthcare.
Market Segmentation:
Type: SNP Analysis, CNV Analysis, Large-Scale Mutation Analysis
Technology: Next-Generation Sequencing, PCR, Microarray, Sanger Sequencing, CRISPR
Application: Oncology, Infectious Diseases, Neurological Disorders, Pharmacogenomics
End User: Hospitals, Research Institutes, Pharmaceutical Companies, Diagnostic Labs
In 2023, the market reached 300 million analyses globally, with NGS dominating, capturing 45% of the market share. This growth is attributed to NGSâs cost-effectiveness and high throughput, revolutionizing diagnostics and genetic research.
Key players like Illumina, Thermo Fisher Scientific, and Qiagen are leading market innovations. With projections indicating a 15% CAGR through 2033, the future of genetic mutation analysis is bright, driven by the integration of AI and machine learning for enhanced diagnostic accuracy.
#GeneticMutationAnalysis #Genomics #PersonalizedMedicine #NGS #PCR #Microarrays #CancerTherapies #TargetedTreatments #GeneticResearch #GeneticTesting #HealthcareInnovation #OncologyResearch #InfectiousDiseases #Pharmacogenomics #DataAnalysis #CloudBased #GeneticDiagnostics #AIInHealthcare #PrecisionMedicine #Biotechnology
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