#dictyostelium

[miserymisume]

real

[bpod-bpod]

Cross-cell Traffic

Visualising and analysing in live cells how one of the least-well understood members of the family of lipid molecules called PIPs regulates trafficking across cell membranes

Read the published research paper here

Edvard Munch, painter of the acclaimed image The Scream was born on this day (12th December) in 1863

Adapted video from work by James H. Vines and colleagues

School of Biosciences, University of Sheffield, Firth Court Western Bank, Sheffield, UK

Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in Journal of Cell Biology, June 2023

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[mycochaotix]

Slime mould! Super cool organisms with super cool life cycles! This is a life cycle diagram for cellular slime mould, Dictyostelium discoideum. Starvation is a main trigger of the amoebae form of rhe organism leading to ‘slug’ forms that transform into a fruiting body thats a sporangium structure atop a basal disc and thin stalk! The amoeba form comes from the fruiting bodies spore germination!🧠🤯

—-

#protozoa #dictyostelium #dictyosteliumdiscoideum

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[microbes-in-hats]

Dictyostelium discoideum with mexican hat 🙏🙏🙏

Added to the list!

[transgenderer]

The culmination of the morphogenesis of the cellular slime mould Dictyostelium discoideum involves complex cell movements which transform a mound of cells into a globule of spores on a slender stalk. We show that cyclic AMP signalling and differential adhesion, combined with cell differentiation and slime production, are sufficient to produce the morphogenetic cell movements which lead to culmination. We have simulated the process of culmination using a hybrid cellular automata/partial differential equation model. With our model we have been able to reproduce the main features that occur during culmination, namely the straight downward elongation of the stalk, its anchoring to the substratum and the formation of the long thin stalk topped by the spore head. We conclude that the cyclic AMP signalling system is responsible for the elongation and anchoring of the stalk, but in a roundabout way: pressure waves that are induced by the chemotaxis towards cyclic AMP squeeze the stalk through the cell mass. This mechanism forces the stalk to elongate precisely in the direction opposite to that of the chemotactically moving cells. The process turns out to be 'guided' by inactive 'pathfinder' cells, which form the tip of the stalk. We show that the entire development is enacted by means of the aforementioned building blocks. This means that no global gradients or different modes of chemotaxis are needed to complete the culmination.

this is so cool. i looooove complex behavior from simple rules

[halomancer]

Alright, I’ve decided to go through with the Model Organism Bracket! I’m going with twelve of the more common species, plus four lesser-known, comment-submitted wildcards. My tentative bracket (unorganized and some common names because I’m tired):

Standard competitors

Mouse

E. coli

Baker’s yeast

Dictyostelium

Drosophila melanogaster

Aspergillus

Arabidopsis

Schmidtea mediterranea

4 yet-to-be-decided

Wildcards

Parhyale hawaiensis

3 yet-to-be-decided

If you have any suggestions, feel free to comment them! The current competition is very animal-heavy and I’d like some representation from other taxa. The list is still subject to change, and probably not in Animalia’s favor.

[luenkel]

ooh I have a neat video showing those slime molds that team up to crawl around (dictyostelium discoideum)

(the video seems to be broken in the app but it should work fine in a browser sorry)

this was part of a lab course were we studied these as an example of an excitable system. the cells give off a signalling molecule (cAMP) and at the same time sense its concentration to adjust how much they produce, creating that feedback loop that gives rise these waves. you can see how everything starts off as many unorganized oscillations but over time a dominant pattern develops that helps them to collect into larger structures.

the reason we can see these signal waves under a microscope like this is because they cause the cells to switch from a round resting state into an elongated travelling state, which changes how they reflect light

the idea of protists is really funny. Ah yes, the kingdoms of life: Animals, Plants, Fungi, and Don't worry about it:)

[science-selected-yura15cbx]

Not just Dictyostelium.

The mechanism of development of the multicellular amoeba Acrasis kona has been deciphered.

In the large evolutionary branch of eukaryotes, which includes trichomonads and the causative agents of meningoencephalitis, there are unusual amoeba-slime molds - akrasia. They are separated by hundreds of millions of years of separate evolution from other well-studied slime molds - dictyostelids. An international group of biologists has published the read genome of a representative of acrasia - Acrasis kona - and its transcriptome at different stages of development. For the first time, scientists have observed which groups of genes are turned on and off in akrasia during the process of building multicellular structures. It turned out that in this process it uses a relatively small number of genes. Many of them are related to the regulatory genes of plants and animals. Now we can better imagine from what genes responsible for multicellular self-organization evolved.

[snailpants]

Surface antigen dynamics in the slime mold, Dictyostelium discoideum

By Gregg, James H

[yeast-papers]

The Dictyostelium discoideum FimA protein, unlike yeast and plant fimbrins, is regulated by calcium similar to mammalian plastins

Pubmed: http://dlvr.it/SwhzCs

[fmet]

S/o to Dictyostelium discoideum. She's crazyyyyyyyyyyy. Love her!!!!!!!!!!!!!!!

[jobrxiv]

Postdoctoral positions in ecology, evolution, and genetics of Dictyostelium Washington University in St. Louis Postdoctoral position in #ecology, #evolution, and #genetics of Dictyostelium discoideum and its #bacteria at the Queller-Strassmann lab in St. Louis! See the full job description on jobRxiv: https://jobrxiv.org/job/washington-university-in-st-louis-27778-postdoctoral-positions-in-ecology-evolution-and-genetics-of-dictyostelium/?feed_id=57439 #ScienceJobs #hiring #research #predation #WUSTL #ecoevojobs Saint Louis #UnitedStatesUS #PostdoctoralFellow

[evoldir]

Fwd: Postdoc: WashingtonU.MicrobialEvolution

Begin forwarded message: > From: evoldir@evol.biology.mcmaster.ca > Subject: Postdoc: WashingtonU.MicrobialEvolution > Date: 3 March 2023 at 06:05:49 GMT > To: rdmpage@gmail.com > > > > Postdoctoral position in ecology, evolution, and genetics of > Dictyostelium discoideum and its bacteria The Queller-Strassmann group > at Washington University in St. Louis has a postdoctoral position for > a highly motivated individual interested in exploring this fascinating > microbial system. Current funding is for studying D. discoideum as a > super-generalist predator, but we are also open to great ideas from you > within the general area of social evolution, symbiosis, and predator-prey > interactions using the microbial organisms we study.to other questions. We > are looking for someone with microbiology experience. Approaches > can include genetics, genomics, microbiome, field, laboratory, and > experimental evolution. > > David Queller and Joan Strassmann lead a friendly and interactive team > of highly motivated, creative, and smart investigators.  Check out > our website, (https://ift.tt/JMRPTO5) > for more information on our lab, or Strassmann???s blog > (https://ift.tt/RzfDP9p). If you are interested in joining our > group, please send an email to Joan Strassmann (Strassmann@wustl.edu) > with a single file including CV, statement of research interests, and > the names, phone numbers, and email addresses of three references. Women > and underrepresented minorities are particularly encouraged to apply. We > will begin reviewing applications by March 20 and will continue to accept > them until the positions are filled. Start date is flexible. > > Joan and Dave > > Joan E. Strassmann > Charles Rebstock Professor of Biology > > Washington University in St Louis > strassmann@wustl.edu > phone: 832-978-5961 > look for my book, Slow Birding, just out! > https://ift.tt/yr0x8iY > > "Strassmann, Joan"

[bpod-bpod]

Follow My Lead

Life is simple if you’re a Dictyostelium slime mould. Most of the time, you spend your days as a free-living single cell in the soil. But when things get tough and food starts running low, you and all your friends send out signals enabling you to come together to form a tiny ‘slug’ that can move further afield in search of a better life. Certain genetic changes (mutations) prevent this slug from forming, but even these mutant slime mould cells can still work together by playing a miniature game of ‘follow my leader’. This video shows individual cells making contact and forming a travelling band that moves together in the same direction in response to chemical signals. This collective cell migration might also underpin many processes in development and disease in more complex animals, such as forming organs and limbs, wound healing, and enabling cancers to spread around the body.

Written by Kat Arney

Video from work by Masayuki Hayakawa and colleagues

Laboratory for Physical Biology, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan

Video originally published with a Creative Commons Attribution 4.0 International (CC BY 4.0)

Published in eLife, April 2020

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[halomancer]

I wanted to argue that slime molds aren’t bugs, but I remembered that this thing

is called a slug.

I must now know your opinion on whether the following organisms are bugs.

Dinocaridids? Hydra? Sponges? Bryozoa? Rotifers and tardigrades are definitely bugs, but are gastrotrichs? Slime molds? I would reckon that flagellated or otherwise motile algae are definitely bugs.

I wonder as well if there is a certain maximum size limit to be a bug. My mind goes to the widest of tarantulas, but I've seen puffball mushrooms bigger than that. What characteristics do you associate with bug-ness?

every thing you mentioned is a bug

[hyaesia]

dictyostelium halloween pfps for me n a friend 🕺🕺