#cure fragaria
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toanw · 3 months ago
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HeartTrace Precure (and their allies)!!
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s4m4ndr13l · 2 months ago
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I opened my sketch commissions over on Ko-fi (on my carrd)!! You can ask me pretty much any character! (fanart, ocs, furry, monster, mecha) if you have a doubt you can always send a message!!
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cogiimyunna · 27 days ago
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FINALLY OH MY GOF
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i-want-men-i-cant-have · 1 year ago
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add me once the servers open 😔✌️
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dimmestmorn13 · 8 months ago
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"...Come here for a bit." "...Okay."
based on the mukuyuki story cg bc the mental image wouldn't leave me alone after ryu-san said romamero were like mkyk in a different font
mini-ficlet under the cut
notes: uses concepts from the timeline theory and the idea that merold remembers timelines with my own spin on it (HCs and such), needless to say it's a bit of an AU/canon divergence from what little we know in fragmem canon
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It starts with the Red Bouquet's first roundtable meeting as a complete unit.
Merold had greeted Hallritt with the typical easygoing callousness Romarriche had expected from his childhood friend. What he hadn't anticipated was that brief flash of animosity. It was a familiar sight, if an oddity by the time and place, because Merold had tensed up as if he'd been in the middle of battle.
Whatever it is that Merold saw in the rookie knight, it bleeds through his actions, and Romarriche can tell that Merold, consciously or not, viewed the man as a threat.
"I would like to think that despite our time apart, I'd still be the one to know you best."
This weariness that looms over his friend is coming to be familiar to him. It's minute. He's seen this before. If it were anyone else other than him, one would be bereft of suspect of Merold ever being in anything else than tip-top shape.
Merold turns to him, that strand of pink hair on top of his head bouncing with the sharp movement as he tilts his head at him with what could be construed as confusion. He knows better, however. "Romarriche? That's pretty sudden to drop on me~" Merold's eyes crinkle with amusement. "If I didn't know better, I'd say you're feeling some jealousy."
"Yes, yes," he humors him, the smile that leaves him is unerringly fond. "However, you do know better."
Romarriche halts, lays his palm flat against his chest, determined. In the middle of the hallways of Lord Marroncream's castle, the two come to a standstill.
"I'm worried." About you.
"You always are. That's just the type of guy you are."
Here's the thing: Merold knows Romarriche just as Romarriche knows Merold. They've known each other since childhood, long before there even was a Merold, the Fragaria of My Melody, and Romarriche, the Fragaria of Marroncream.
"You've been having nightmares." He says slowly. It's come back to him. This had happened before Merold left to travel around the continent. There hadn't been a cure then, he hopes there would be a cure now.
There's a small breadth of distance between them, and yet somehow, Merold seemed no less further away than when he'd been out and about and doing his work. Yet, most intriguingly, "And Hallritt seems to be the trigger, however odd that notion be."
Merold does not respond.
"…Come here for a bit."
Until he does, and Romarriche has always been weak for his childhood friend, and so, he obliges him.
"…Okay," Romarriche says, stepping forward until he and Merold were face to face. Or as much as they can be, when Merold hadn't grown since the last time he'd seen him, leaving the gates and waving goodbye to fulfill the duties expected of the Greatest Knight.
They had been the same height, then.
Merold places his head onto Romarriche's shoulder, hands shaking where he held onto Romarriche's pink coat. His neck tickles at the shuddering breath Merold releases.
Romarriche figures he wouldn't say anything about the sniffles. Nor the wetness that spreads across his shirt.
"Okay," he repeats, wrapping his arms around his friend. "I'm here."
(Romarriche felt real.
In this world that continued to change, Romarriche felt real and alive. He may not remember like he did, but his presence was a comfort that Merold never realized he'd taken for granted, much in the same way those instances of losing Kurode continued to haunt him.
He doesn't know what tipped the man off in this run of events. He'd confronted him before, in the past timelines, but ultimately left the matter well alone before Merold could succumb to the notion of telling his childhood friend anything.
Perhaps, it was Merold himself that had changed. Whichever it was, one thing was certain.
This warmth…
I won't forget this.)
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cloudmail-bah · 29 days ago
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could we please have a medicalcore masculine alter? he has kind of a sanrio-liking vibe, so if you wanna choose a specific character to base them off of that'd be cool! thank you! <3
absolutely!! i loved making this request i love sanrio X3c
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☁️ Requested Package 📬 Dr. Sanrio !!
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💌 headmates may not turn out exactly as the information below! that's perfectly fine, pick and choose what works💕
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Names: Melody, Mel, Max, Medic, Harold, Doc, Alex, Berry, Lucus, Ash, Zol
Pronouns: he/him, Medi/medicine, heal/heals, cure/cures, health/healths, needle/needles, scar/scars, psy/psyche/psyches, heart/hearts, melody/melodys, bunny/bunnys, bun/buns, pastel/pastels, swirl/swirls
Genders / Orientations: masc-cassgender / pansexual, panromantic, nebularomantic, nebulasexual
Age: 20-30 years old (he's got that doctors degree!)
Species: human! but i feel like bun can also become a bunny (melody bunny :3)
Roles: Medic, Consumanaut, Jack of all Trades, Trauma holder
Sources: My Melody from Sanrio, Merold from Fragaria Memories, and Medicalcore (??)
Likes: bunnys, pink, taking care of oneself, cute things, taking it slow, reading, taking walks, enjoying nature, pets, taking pictures, writing / journaling, indulging in things that make the body happy, laying down, melody (sanrio)
Dislikes: being sick / hurt, people not taking them seriously, being told off for concerns, people not listening to their bodies needs (very protective about others/the system), people invading his personal space
Personality: methodical, intelligent, slow, patient, silly, charismatic
Faceclaims:
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Extra: favourite color is #92e9c8, thinks rock music is hard on the ears so he doesn't listen to it!
Sigh Offs / Emojis: 🐇, 🩺, ❤️‍🩹, 🎀
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mew-cake · 25 days ago
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Things I've actively working on rn!!
Magia Record design reviews part 2
Smile Force vs Glitter Cure
Fragaria Memories
The status of those things are thusly!
For design reviews, I'm currently cutting down audio. It's! Very long! We talked for like two hours! I gotta cut down all the blabber!
Still watching through the series. It's a time alright! I'm making notes as I go, and hopefully I'll be able to get my thoughts across
Writing the script! This is very much a niche interest but something I really wanna talk about just for funsies.
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mikaerun · 1 year ago
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Pinned Post in which I list my interests for ease of access and hope something sticks
Hello I am Mikael I am trans and gay and 22 and a yumedanshi.
Music Media I like:
Bandori
MILGRAM Project
Otogi no Uta
FromArgonavis
Vocaloid (doesn't count because it's not a project per se but eh)
Muse Dash
Project Sekai
Love Live
Idolm@ster (SideM > Deresute > Mirishita)
Hypnosis Mic
Paradox Live
Ensemble Stars
Handead Anthem
Actors SongConne
Fragaria Memories
Hanadoll
Dear Vocalist
D4DJ (if you squint)
Denonbu
KagePro
Music Artists I like mostly Vocaloid:
Syudou
Eve
¿?Shimon
Sumia
Kanaria
Pinocchio-P
Surii
Harumaki Gohan
Kairiki Bear
John/Tooboe
Deco*27
Hiiragi Kirai
Azari
Nayutalien
Guchiry
Nuyuri
Balloon
Utsu-P
Rusino
Ayase
Roselia
Morfonica
Street Story
Kikuo
Lamiya
Animanga I enjoy:
Madoka Magica
Death Note
Zombieland Saga
Blue Lock
Chainsaw Man
Pretty Cure
Wotakoi
Kuroko no Basket
OshiBudo
Little Witch Academia
Love Chuuni
Nanbaka
Nagatoro San (sorry)
Videogames I like:
Pokémon
Fire Emblem (3H, Engage)
Project Diva
Muse Dash again
Animal Crossing
Super Mario series
Celeste
A Hat In Time
Among Us
Undertale And Deltarune
Fnaf
Yo-kai Watch
Geometry Dash
Obey Me
Ace Attorney
Minecraft
others
Not Anime or Manga But I enjoy:
Scott Pilgrim
OCs
Seiyuu
Sanrio
Vocaloid
Animals
OCs again
Last one for now.
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magicalgirlagency · 1 year ago
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It's impressive how Murase Ayumu has landed into voice-acting roles of three avian-based characters:
Hinata Shoyou, from Haikyuu!!. Started out as a volleyball player in Karasuno, a crow-themed team;
Yuunagi "Cure Wing" Tsubasa, from Hirogaru Sky PreCure. A chunky orange little bird that can shapeshift into a human;
Tuxam, from Fragaria Memories. A knight who serves and protects Tuxedosam, a penguin mascot.
Plus, if Tsubasa turns out to be a repugnant criminal after the 40th episode, I'll at least have two other birdy boys to go to. If you know you know.
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valgasnewsthings · 1 year ago
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Where are to find vitamins on spring?
At summer, we are eating fresh fruits, berries, vegetables and receiving lots of vitamins.But on spring   we are  eating citric lots of, cabbage, apples, green onion, and porridges eat of cereals whole, bean, meat, liver.
Everyday drink glass of fresh pressed juices, and useful mix of carrot, apple and orange, beet,  celery, potato, cranberry.
Drink infusions of vitamins as of hibiscus, he is rich beats record by vitamins B, C,E, PP, AND BENEFIT DRINK TEA of mixed herb oregano, hypericum, mint, leafs of fragaria vesca, buds or leafs of black currant, inflorescences of raspberry, ash berry red berries, and chop mixed mass, add hot water, drink ,like a tea.
At home on your window grow fresh greens as  petroselinum, dill, onion, seeds of sprouts millet, natural are better, than from market.
Minimal warm manufacturing   vegetables and fruits, raw, are benefit more. Remember about dandelion, as a rich he is with phosphorus, in salad his bitterness as of leafs masking with garlic or onion. Not opening buttons using, like capers, as marinading. Infusion cure skin, low acidity gastritis, hypertension, insomnia , as 2 tea.sp. of roots add in 250 ml. of cold water, boil minute, in ten min filter, use on glass for 2 times/day for 4 weeks.
At home, am preparing remedies against migraine.
After stress, migraine attacked me with strong headaches and rings. And knowing about remedies,  am cooked and cured at home.
Sweeten water 1/3 of glass add 30 drops of horse chestnut tincture, am used her, in half hours felt better, and on the next day again repeated and ache stopped.
50 gr of grinded with brown peel add in 0.5 l. of vodka, infuse 2 weeks, at dark place, use on 30-40  drops with sweeten water before meal.
Sophora Japan mix with white mistletoe, leafs of hazelnut, fruits of horse chestnut, add 0.5 l. of vodka, in dark place infuse for 21 days, use dessert spoon one with water for 3 times/day before meal.
In hypertension, headaches, trombophlebitis, varicouse veins widening, rheumatism, adenoma prostate, stenocardia, against thrombus and for strengthening  walls of blood vessels use this balsam as on ten gr chopped chestnut horse add in glass of vegetable oil, infuse for 7 days in dark place, after on water bath lead till boiling, remove from a fire. Cool, and add in bottle of dark glass, and rub ache parts as before sleep.
from Valga s health news,gardening,and cooking ,and beauty . https://valgasnews.blogspot.com/2023/07/where-are-to-find-vitamins-on-spring.html via https://valgasnews.blogspot.com/
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cloveletter · 9 months ago
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ooooo this is a fun tag game!! I’m gonna use my multi media music project playlist for this!
C - Cure - Alien Stage
L - Lower One’s Eyes - Nulut
O - One Sheep - VBS (I forgot the producer…)
V - Villain - Teniwoha
E - Endless Dream - Visty
L - Life is Beautiful - The Cat’s Whiskers
E - Ever Red - Fragaria Memories (RED BOUQUET)
T - Trust Nobody - Cozmez
T - Trigger - Gokuluck
E - edN - 1Nm8
R - Rap Guerilla Reload - Paradox Live
@lotusrue you know what to do
And also anyone who wants to join!! Though some of my mutuals might have a hard time with this cus they have a lot of numbers in their users… still!! A fun challenge if you wanna try!
Welp. Tag tagged by @justplaggin for the game
rules: spell out your name or url with songs
I couldn't resist, and thank you very much for it, Jay/Plagg!
To challenge myself, I'm gonna see if I can stick to songs from anime East Asian shows/stories
A - All-in (Alien Stage)
L - Last Dimension (TRIGGER)
W - wi(l)d-screen baroque (Revue Starlight)
A - Artistic Partisan (ALKALOID x Valkyrie)
Y - Yumemiru Architecture (Kagehira Mika; Enstars)
S - STRONGER & STRONGER (Zool)
A - Ame (MEZZO)
J - Joker Flag (IDOLiSH7)
O - OMEGA (STEREO DRIVE FOUNDATION; Yuukoku no Moriarty)
Y - Yume Shizuku (Re:vale)
F - Forever Note (MEZZO)
U - Until it Dies (覃云; Link Click)
L - Lily (Luck Life; Bungo Stray Dogs)
N - Now and Then (Re:vale)
O - Or the Beautiful Golden Drop (Knights; complete version out on May 22, so have the game version)
T - THE POLiCY (IDOLiSH7)
E - Eccentric Party Night!! (Five Eccentrics)
19 songs...and I tried to find ones that I genuinely enjoy right now (RIP to me making this challenge harder), so hence, the above mostly-Japanese-dominated list.
No pressure tags: @bobisnolongerhere @lizzieonka @rosencrantzsguildenstern @msperfectsheep-posts @mahounonbinary @praise-the-lord-im-dead @nitunio @akitchenknife @teslathelame @koi0boi @mihai-florescu @forebodinglight @imissthembutitwasntadisaster and anyone else seeing this because i am now incredibly curious about what songs you will choose (im so sorry if I forgot someone)
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othmeralia · 5 years ago
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Strawberry Fields Forever
Fragaria vesca L.: or Wood- strawberry, 1893
Part of Plant-atlas to "My water-cure," : containing sixty nine pictorial representations of all the medicinal-plants mentioned as well a some others in general use among the people. 
Author: Sebastian Kneipp
Original Image: Kneipp, Sebastian. “Fragaria Vesca L.” Plant-Atlas to "My Water-Cure," : Containing Sixty Nine Pictorial Representations of All the Medicinal-Plants Mentioned as Well a Some Others in General Use among the People. Kempten, Germany: J. Koesel, 1893. https://digital.sciencehistory.org/works/kw52j9144.
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ilydzy · 4 years ago
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hey everyone.
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ok fine.
i’m lydz/roru/axl/etc.
prounce are he/him, fi/fizz, gli/glim.
i like girly shit and nerdy shit and nerdy girly shit.
i’m 23.
this blog mostly runs on a queue.
oshis are saeran choi 💖 (#1) and leviatan 🐍 of obm (#2). i am their yumedanshi.
i’m currently playing twst (reading ignihyde book as of updating this), cupid parasite, cafe enchante, the ssum, and obey me: nightbringer. “currently” tab in blog desc is what i’m hyperfixated on.
other oshi (fictional characters):
mitsuo ayase 📷 (aoppella; #3, rest aren’t ranked)
cecil aijima 🐈‍⬛ (utapri) (/r)
chilchuck tims (delicious in dungeon) (/r)
kuusuke saiki 😵‍💫😵‍💫😵‍💫 (saiki kusuo no psi nan) (/r)
tobio kageyama (haikyuu!!)
taako from tv 🌮 🌂 (the adventure zone: balance) (/r)
elena amamiya / cure soleil ☀️ (starpre)
hana nono / cure yell 📣 (hugtto)
mizuki akiyama 🎀 (prsk)
pompompurin 🐶 (sanrio)
relatedly, kouta hasegawa 🐶 (sanrio danshi)
agent 3/captain 3 of splatoon 🦑
kurode (fragaria memories)
clover vermillion / amethyst heart 🍀 (magical warrior diamond heart)
arima kana 🤍🧂 (oshi no ko)
oshi idols/biases
**manase mana 🍬 (formerly MyφMe) (kamioshi)
amasawa rito 🦈 (meme tokyo. & dempagumi.inc)
momo 🍑 🐻 🦕 (twice, ult group)
jeongyeon 🐶 (twice, ult group)
seokyoung 🐹☀️ 💜 💛 (GWSN)
beomgyu 🧸🐻 (txt)
hueningkai 🐧 (txt)
pengy artemisa 🐧💛🪐 (reso!)
berry 🍓 (soloist)
nina 🧸 (non sweet)
pan ranger 🍞 (soloist)
eggu 🍳 🥚 (idolusion!)
ririsa 🌱 (idolusion!)
kim lip🦉❤️🔴🌹 (loona/loosemble)
arthur 🐿️ (kingdom)
alex 🦖 (formerly drippin)
miquella (mxfruit)
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biothera-indonesia · 5 years ago
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BIOTHERA INDONESIA
Biothera is a management that manages innovative health care services that always use the main ingredients of bio-essence (Herbal / Botanical which contain pure natural vitamins & minerals), such as: Lemon Citrosa, Dahlia Astera, Mentha Phillia, Cybidium Orchid, Myrciaria Dubia, Acacia Fabace , Arabium Olea, Matricaria Chamomile, Echinachea Gerbera, Frangi Plumeria, Hibiscus Coralline, Hylocereus Costa, Cashmere Hymeno, Yuzu Juno, Albern Fragaria, Aswego Alstroe, Jasmine Mosa, Alamanda Prunus, Magnolia Grandi, Hylocereus Costa, Cashmere Hymeno, Yuzu Juno, Albern Fragaria, Aswego Alstroe, Jasmine Mosa, Alamanda Prunus, Magnolia Grandi, Yohju Matsu, Rosalea Marva.
Which is efficacious: nourish the skin, provide freshness to the body, cure fatigue, muscle aches, aches, aches & pains.
The work of Biothera covers the fields of health care: biotherapy massage, biotherapy body scrub, biotherapy mask, detox biotherapy, shiatsu / ashiatsu, chakra biotherapy (totok aura), iluma biotherapy (facial facial treatment and full-blooded face), qwax biotherapy (removing body hair) & hydrofuse biotherapy.
Terms of work at Biothera:
1. Male, age 20-35, Already graduated from high school & not currently married
2. Minimum Height 165cm & Minimum Weight 62 kg.
3. Look attractive & proportional
4. Healthy Physical & Non-Smoker
5. Be Good & Polite (No Plus Plus & No Drugs)
6. Be Diligent & Serious at Work (Not Often Skipping / Off)
7. Understanding the Basic / Procedures for Therapy
8. Those who have no experience will be guided / taught until they can
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kaiyodei · 5 years ago
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facebook deleted my note so i’ll keep one here
---things that cure, treat, thwart or slow cancer. effective or not,  in vitro or not. with varying degrees of toxicity and processing--  thangs big pharma don’t want you to know.
714X(trimethylbicyclonitramineoheptane chlorid) Abelmoschus esculentus (Okra) Abrus Acidianus virus Actaea racemosa (or black cohosh) Acupuncture ADOPTIVE cell transfer AHCC Arctostaphylos uva-ursi alkline diet Allium cepa (extract) Allium nigrum (Black Garlic) ? Allium sativum? (Maillard reaction) Almonds alterd polio/polio vaccine Amaryllidaceae (spider lillies) Amblyomma cajennense( saliva compounds from Cayanne tick) Amomum subulatum (black cardamom) Elettaria (green) Andrographis paniculata anethum graveolens(dill) Annona muricata (soursoup) all other Annona genus/  Annonaceae family anti fungals? Anti-cancer psychotherapy antibiotics Antineoplaston therapy ANTI NEO PLASTONS Apitherapy Applied kinesiology Apricots (kernels/seeds) ARGININE (1-ARGININE arsnic trioxcide Artemisia annua ( wormwood/sweet annie/sweet sagewort/annual mugwort or annual wormwood) ARTEMISININ AVEMAR Bach flower remedies Bhasmas minerals, metals and jems barefoot walks in the connifer forest battery acid (*only listed in case it -does- destroy tumors in a petridish) Bean sprouts bee propolis beer(hops?) Berlinia grandiflora BETA GLUCANS, 1, 3, 6 biblical diet bioactive polysaccharides BIOMAGNETISM black cumin (Bunium bulbocastanum?  Nigella sativa ?) Black salve Blackberries bleach (possibly, in vitro only)https://www.cancertutor.com/chlorine_dioxide/ Blood (Turtle, Alligator, ) Blueberries boswellic acids (Frankensence) BOVINE CARTILAGE Breuss diet Buckwheat Budwig diet Caesium chloride Cancell Cancer guided imagery canna Cannibis oil Capsicum annuum (Guinea spice, cow-horn pepper, aleva, bird pepper) Carctol carotene Carum carvi (caraway) Cashews Catharanthus roseus (rosy periwinkle/teresita) Cavia porcellus (guniea pig ,with  ritual) chelaton therapy Chelidonium majus. Chlorella chlorophyll chloroquine Citrus limon Osbeck (lemon) Citrullus lanatus (watermellon) Clark's "Cure for All Cancers" coffie enemas Coix lacryma-jobi (jacob's tear/job's tear) Coley's Vaccine therapy Colloidal silver colorpuncture CONJUGATED LINOLEIC ACID OR CLA Contreras Therapy Convallaria majalis Convolvulus (bindweed) CoQ10, Coral calcium Coriandrum sativum (corriander) Craniosacral therapy Crocus sativus (safforn) Croton lechleri Cruciferous vegetables Cucumis sativus (cucumber) cucurbitacins Cuminum cyminum(cumin) cupping Curcuma longa (tumeric) Cytokine therapy D-GLUCARATED daffodill (Amaryllidaceae?) dasatinib dance detox footbath, with intravenous vitamin therapy, cranial electrotherapy stimulation, combination infrared waves plus oxygen, acupuncture, colon hydrotherapy, Di Bella Therapy DI-INDOLE METHANE (from cabbage) Dieffencachia maculata,(dumb cane) Dionaea Muscipula (Venus flytrap Carnavoria brand extract, anti tumor?) disulfiram/Antabuse DMSO dry fasting ear candeling Elderberries Electro Physiological Feedback Xrroid Electrohomeopathy elephant P53 and TP53 Elettaria|Amomum|Zingiberaceae (Cardamom) Ellagic acid emu oil EPICAN FORTE® Erecial dysfunction drugs (for after tumor removal surgery) Essiac tea = ( burdock (Arctium lappa), sheep sorrel (Rumex acetosella), slippery elm bark (Ulmus rubra), and Indian rhubarb (Rheum officinale) or turkey rhubarb (Rheum palmatum).[3] Some formulations may also contain watercress, blessed thistle, red clover, and kelp) Eugenia caryophyllata (clove) Euphorbia tirucalli (firestick) Eutrema japonicum/Wasabia japonica (wasabi) Fallopia japonica/Reynoutria japonica (Japanese Knotweed) FAR INFRARED THERAPY fasting Fava beans ferro fluid FLAVONOIDS Foeniculum vulgare (fennel) Fontainea picrosperma (Blushwood berry) (Hylandia dockrillii ..?) Fragaria? (strawberries /) FUCOIDAN GcMaf and transforming-growth-factor-beta GEIPE THERAPY Gelsemium elegans (heartbreak grass) Germanium German New Medicine (GNM) ginger tea Gingerol Glyconutrients gold Goldenseal (or Hydrastis canadensis) Gonzalez protocol Gotu kola Guiera senegalensis HANSI THERAPY heat HIV Hordeum vulgare (barley) Hoxsey therapy HULDA CLARK'S THERAPIES human breast milk Hydrazine sulfate hydrogen-peroxide Hyperbaric oxygen therapy hypnosis HYPOTHERMIA THERAPY IMMUNOCAL® Indole-3-carbinol (found in broccoli) Influensa Vaccine (for after tumor removal surgery) Inonotus obliquus(Chaga) Insulin potentiation therapy IP6® IPT (INSULIN POTENTIATED THERAPY) Issels treatment juicing Junk DNA k3 Kalanchoe Kangen Water Kelley treatment KEYTRUDA kinase inhibitors Krebiozen Krebiozen LACTOFERRIN
laetrile/laevo-mandelonitrile-beta-glucuronoside,/amygdalin/Vitamin b 17/Nitriloside lapacho tea laughing Lauraceae (cinnamon) Larotrectinib Ligustrum lucidum (Glossy privet) Linalool Lima beans limonene Lipoic acid Live blood analysis LifeOne Protocol Livingston-Wheeler Therapy Lorraine Day's  10-step program low sugar diet lye lymphatic drainage LYMPHOTONIC PF2 Macadamia nuts Macrobiotic diet magnets meditation Metabolic therapies MGN3, Millet Miracle Mineral Supplement MG-LZ8 (Ganoderma lucidum ) MODIFIED CITRUS PECTIN Moerman Therapy Momordica charantia (bitter mellon) Morinda citrifolia (noni) Moringa oleifer (moringa/ drumstick tree/horseradish tree/ ben oil tree/or benzoil tree Moxibustion MYCOSOFT GOLD® naked mole rats don't get cancer N-TENSE® Neuro-linguistic programming Nieper therapy Ocimum sanctum/Ocimum tenuiflorum (holy basil) oleander OMEGA 3 FATTY ACIDS Oncolyn® Oncotox® Orgone Origanum vulgare (oragono) Orthomolecular medicine oxygen therapy P53 genes P80 Natural Essence Panchagavya pangolin Pau-d-arco Peperine Peristrophe bicalyculata Persea americana (avacado, the pit part) pH Balancing Phyllomedusa sauvagii phytoestrogen phytolacca decandra (American pokeweed) Picea(spruce genus)Alpha- & Beta-Pinene Pimenta dioica.(allspice) platinum Plumbagin (see carnavoria?) Plumbago zeylanica (ceylon leadwart) Polarity therapy Poly-MVA Polybia paulista venonm (a wasp) Poria cocos/Wolfiporia extensa (hoelen/ poria/tuckahoe/ China root/fu ling/matsuhodo Portulaca Oleracea (Purslane) positive mental outlook prayer(??) proanthocyanidins Proteolytic enzymes Protomorphogens Prunus avium and P.cerasus (cherry)Prunus africana Psychic surgery purple rice Qigong quark cheese and flax (http://www.getholistichealth.com/41061/the-industry-suppressed-budwig-protocol-or-how-to-cure-cancer-with-cottage-cheese/) Quercetin radiation Radiosensitization raido frequencies Raspberries Rauvolfia serpentina (or snakeroot) reiki Resveratrol Revici's Guided Chemotherapy Rhinella marina venom (cane toad) rhinocerous horn ricin RIGVIR Rosmarinus officinalis(rosemary) Sanguinaria canadensis (bloodroot) sea cucumber (Holothuroidea?) sea silver seeds from other fruits like apples, cherries, peaches, prunes, plums, pears Selenium Serenoa repens (saw palmetto) shark cartilage Shiatsu Silybum marianum (milk thistle) smelling farts smoothie:https://pinklotus.com/wp-content/uploads/2017/11/DrFunksAntioxidantSmoothie.pdf sodium bicarbonate (bakingsoda) Sorghum sour honey Stellaria media (chickweed) Strawberries Strychnos nux-vomica(Strychnine tree) sun light swiftlet nests Taraxacum (dandilion genus) Taxus wallichiana (Himalayan yew) Thapsia garganica (deadly carrots) this salad http://realfarmacy.com/make-giant-cancer-killing-salad/ Thymus vulgaris (common thyme) Tigilanol_tiglate /ebc-43(from blushwood berry) TO-MOR-GONE Trametes versicolor/Coriolus versicolor/olyporus versicolor  (turkey tail mushroom) Transfer Factor Plus Trifolium pratense (red clover) Tripterygium wilfordii(thunder god vine) urine , cow, dog (http://www.cowurine.com/cancer.html) Ultraviolet Blood Irradiation Uncaria guianensis, Uncaria tomentosa (or cat's claw) varicella vegan diet Venom Peptieds (various spider and pit viper species, arazonian bark scorpian) VG-1000 VIBE Machine vibrations Vinblastine Virginia Livingston Therapy Viscum album (misletoe) (Iscador) Vitacor vitamin c (ascorbic acid ? ) vitamin D waiting for your immune system (http://www.getholistichealth.com/41065/the-american-cancer-society-admitted-that-untreated-cancers-often-go-away-naturally/) Waxy monkey tree frog, skin compounds wheatgrass Whipple Procedure, Wigmore therapy Withania somnifera(Indian ginsing/ zapotin Zingiber officinale (ginger) Zoetron therapy
http://www.getholistichealth.com/40674/the-miracle-drink-that-kills-cancer-cells/
•Fava beans •Raspberries •Strawberries •Blackberries •Blueberries •Buckwheat
•Macadamia nuts •Bean sprouts All are the highest sources of absorbable vitamin B17.
https://cancerwontbeatme.com/2014/10/02/a-list-of-78-proven-therapies/#more-164 https://thetruthaboutcancer.com/medicinal-mushrooms-cancer/
https://www.npr.org/sections/health-shots/2017/07/12/536812206/living-drug-that-fights-cancer-by-harnessing-the-immune-system-clears-key-hurdle?utm_source=facebook.com&utm_medium=social&utm_campaign=npr&utm_term=nprnews&utm_content=20170712
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biomedgrid · 5 years ago
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Biomed Grid | Comparative Evaluation of Total Phenolics, Total Flavonoids Content and Antiradical Activity in Six Selected Species of Family Rosaceae Using Spectroscopic Method
Introduction
Polyphenolics like phenolics and flavonoids exhibit diversify range of biological activities. These Phyto-compounds play a defensive role against antimicrobial diseases [1]. Fruits are the enrich source of polyphenolic compounds and utilization of fruits have showed a significant role in curing countless human disorders [2]. All the selected species of Family Rosaceae possessed therapeutic importance i.e. Pyrus communis aerial and flowering parts are a source of traditional medicine as they exhibit anti-inflammatory properties. [3] Prunus armeniaca possessed wound healing properties in normal rats, Prunus armeniaca is the enrich source of natural antioxidant and play an important role against cardiovascular diseases, anti-microbial as well as skin related issues [4], Malus pumila possessed polyphenols that have beneficial effects on health, such as exhibiting antioxidant activity, antibacterial, anti-inflammatory, anti-radiation, antitumor and anti-obesity effect [5,6], Prunus persica leaf and fruit exhibited anti-tumor, anti-allergic, anti-inflammatory, anti-oxidant activities [7], Prunus domestica possessed various phenolic acids and flavonoids which allow their use as nutraceuticals in current market due to their preventive and therapeutic nature [8], The berries, leaves, and roots of Fragaria vesca have all been used as a folk medicine for diarrhea and the stalks for wounds, for cardiovascular diseases like cancer and heart related disorders [9].
Natural antioxidants gain immense importance as they impose less or no side effects in comparison to Synthetic antioxidants. Antioxidants played a significant role in scavenging free radicals as free radicals lead to serious health issues like neurological disorders, Cancer and so on. Natural antioxidants are of great concern for the researchers of this field as they have shown profound results in comparison to synthetic antioxidants [10]. The present study illustrates the qualitative phytochemical screening and quantitative profiling of total phenolics, flavonoids content and anti-radical potential of selected six species of Family Rosaceae. Ethanol gave preferable results in comparison to methanol extracts. A significant correlation exhibited between all the parameters which impart a specific and important role in many biological activities. Hence this research provides base line for the use of these plant species in different biological activities which include anti-cancer, antidiabetic and neurological disorders etc.
Experimental SectionPlant Material
The plant parts (Leaves/Bark/Fruit) of all the selected six species of Family Rosaceae were collected from Jinnah Garden, Lahore in the months of Feb-May (2016), authenticated and identified by Dr. Mir Ajab Ali Khan, Professor Department of Biological Sciences, Quaid-e-Azam University, Islamabad, deposited in the Prem Madan Herbarium of Lahore College for Women University, Lahore (Pyrus communis Voucher No: LCWU-15-123, Prunus armeniaca Voucher No: LCWU-15-125, Malus pumila Voucher No: LCWU-15-116, Prunus persica Voucher No: LCWU-15- 124, Prunus domestica Voucher No: LCWU-15-99, Fragaria vesca Voucher No: LCWU-15-127).
Extracts Preparation
Leaves/ fruit/ bark of selected six species undergo double maceration protocol for the extraction of plant extracts at 21°C via two polar solvents i.e. methanol and ethanol [11].
Phytochemical Screening
Phytochemical screening was performed for alkaloids, phenolic acids, Flavonoids, terpenoids and tannins. The color intensity or the precipitate formation was used as analytical responses to these tests (Table 1) [12-19].
Table 1:Phytochemical Screening of six selected species of Family Rosaceae.
Quantitative Detection of Total Phenolics & Flavonoids Content
Folin-Ciocalteu (FC) reagent was used to assess total phenolic content in the test sample, phenolics presence in the test sample resulted in formation of blue complex (phosphotungstatephosphomolybdate) using gallic acid as a standard. Gallic acid calibration curve provides as a baseline for the determination of TPC content [20,21] (Figure 1a & 1b). Aluminium chloride (AlCl3) method was used for the detection of total flavonoid content (TFC), on reaction of test sample and aluminium chloride appearance of yellow color is the indication of presence of flavonoids. Quercetin calibration curve was used as a standard for the measurement of flavonoids (Figure 2a & 2b) [22,23].
Figure 1a: Calibration curve for Gallic Acid.
Figure 1b: Total phenolic content (mg Gallic acid/g dry plant extract).
Figure 2a: TFC (mg Quercetin/ g dry plant extract).
Figure 2b: Calibration Curve of Quercetin (mg/ml).
Antioxidant Potential
Methanolic & Ethanolic Leaves/Bark/Fruit extract of selected species of Family Rosaceae was estimated for radical scavenging activity by means of DPPH assay. Tested samples were assessed at four different concentrations i.e. 0.125, 0.25, 0.5 and 1mg/ mg/mL. Add 50μL plant extracts in methanol/ethanol solution of DPPH (5ml of 0.05mM) leave it for half hour then absorbance was measured at 517nm. Conversion of deep-violet color to light yellow is the clear indication of the presence of antioxidants. Results were compared with the positive control used in the test (Figure 3 & Figure 4) Half minimal concentration was assessed by means of Graph pad prism 5.04 software (Figure 5) [24,25].
Figure 3: % inhibition DPPH Radical Scavenging Activity using Methanol as a Solvent.
Figure 4:% inhibition DPPH Radical Scavenging Activity of six species of Family.
Figure 5: Half Maximal Inhibitory Concentration (IC50) of six species of Family Rosacea along with artificial antioxidants.
Statistical Analysis
Mean ± Standard deviation of three parallel measurements were done using SPSS software, Microsoft Excel and Graph pad prism Software 5.04 [26].
Results and Discussion
The results were gathered in Table 1. It is noteworthy that the presence of flavonoids, phenolics and tannins in all six species of Family Rosaceae, terpenoids presence was indicated in all the five species which absence of terpenoids was reflected in P. persica. However, absence of alkaloids was observed in Prunus persica, Prunus domestica, Fragaria vesca while other three species Pyrus communis, Prunus armeniaca, Malus pumila showed the presence of alkaloids (Table 1).
Six selected plant species of family Rosaceae was assessed for total phenolic content (TPC). Among tested samples Fragaria vesca (Leaf) showed Maximum TPC content i.e. 3.314±0.28 mg GE/ g dry plant extract while minimum phenolic content was reflected in Prunus domestica (bark) 1.0699±0.2 mg GE/ dry plant extract using 70% ethanol as solvent. Ethanol proved to be an excellent solvent in extracting phenolic acids at both inter and intra cellular level [27]. Similar outcomes were obtained by the work of different researchers [28,30]. Results were given in Figure 1. Most diversified groups of phytochemicals found in all plant organs are termed as Phenolics [31]. Phenolic compounds found in plants have a diversified range of functions including anti-inflammatory, antiradical, antitumor, antidepressant activities etc. and so on [32]. Variation in the Phenolics content was observed based on solvent used [33].
Results showed that 70% ethanol was used for extracting maximum flavonoids content by Fragaria vesca i.e. (4.84±0.17 mg QE/g of dry extract) while 2.952±0.13 mg of QE equivalents (GAE)/g dry weight flavonoid content was achieved with methanol. Role of flavonoids was well known in the medical field as it prevents from antimicrobial, cancerous and hepatoprotective problems [34]. Figure 2a&2b illustrate the following results.
DPPH assay was used for estimating radical scavenging activities in six selected species of Family Rosaceae and Moraceae. All the selected species of Family Rosaceae and Moraceae showed strong antiradical capabilities in comparison to the positive drugs used i.e. Ascorbic Acid, Quercetin, Butylated Hydroxytoulene and Vitamin E (Figure 1&2): Antioxidant potential was found to be best in ethanol rather than methanol (Figure 3&4) and was in the following order: Prunus domestica (Leaf) ≥ Prunus armeniaca (Fruit)≥Fragaria vesca (Leaf) ≥ Prunus persica (Leaf)≥Pyrus communis (Leaf) ≥ Prunus domestica (Bark) 96.13±0.21≥96.06±0.27≥ 94.92±0.21 ≥ 94.22±0.04 ≥ 91.70±0.40≥91.70±0.40.
Results obtained from the current research work strongly correlate with the work of different researchers observed that presence of secondary metabolites gave P. acerifolium leaves strong radical scavenging abilities. Antioxidant rich plants have shown significant potential in the curing of multiple disorders like antitumor, proapoptotic and antiangiogenic effects [35]. IC50 value was also calculated with the help of Graph pad Prism 5.04 software (Figure 2).
Conclusion
Hence, conclude that all the six species of Family Rosaceae are enriched source of phytochemicals like phenolics, terpenoids, alkaloids, tannins and flavonoids and the radical scavenging properties of all the six species is due to the phytochemicals present in them. Results showed there is a strong correlation between phytochemicals and anti-radical properties of plant samples under investigation. Maximum Phenolic and Flavonoid contents were found in Fragaria vesca L. using 70% ethanol as solvent. This research is of great significance as all species acted as potent antioxidants and thereby lead as a baseline for the treatment of multiple disorders like anti-cancer, antidiabetic properties, neurological disorders like Alzheimer or Dementia.
Acknowledgements
Special thanks to Dr. Mir Ajab Ali Khan, Professor Department of Biological Sciences, Quaid-e-Azam University, Islamabad for identification of plants.
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