#chronicdiseaseday

[budandtender]

Unlocking the Power of Endocannabinoids: A New Frontier in Battling Chronic Diseases

International Chronic Disease Awareness Day 10 July

Introduction

Endocannabinoids are naturally occurring compounds found within the human body that interact with the endocannabinoid system (ECS). This system plays a crucial role in regulating various physiological processes, including mood, appetite, pain sensation, and immune function. Recent research has shed light on the potential of endocannabinoids in managing chronic diseases. This article explores how endocannabinoids can regulate chronic diseases without discussing the medical uses of cannabidiol (CBD).

Understanding the Endocannabinoid System

The ECS is a complex cell-signalling system comprising three main components: endocannabinoids, receptors, and enzymes. The two primary endocannabinoids are anandamide and 2-arachidonoylglycerol (2-AG). These molecules bind to specific receptors, namely CB1 and CB2, which are predominantly found in the central nervous system and immune cells, respectively. Enzymes such as fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL) are responsible for breaking down endocannabinoids once they have fulfilled their purpose.

Regulation of Inflammation and Immune Response

Chronic inflammation is a common denominator in many chronic diseases, including arthritis, diabetes, and heart disease. Research has shown that endocannabinoids play a vital role in modulating the immune system and controlling inflammation. By binding to CB2 receptors, endocannabinoids can reduce the production of pro-inflammatory cytokines and promote the release of anti-inflammatory cytokines. This modulation of the immune response helps maintain a balance between pro- and anti-inflammatory signals, potentially reducing the severity of chronic inflammatory conditions.

Neuroprotection and Neurodegenerative Diseases

Neurodegenerative diseases, such as Alzheimer's, Parkinson's, and multiple sclerosis, are characterized by the progressive loss of neuronal function. Studies have demonstrated that endocannabinoids can exert neuroprotective effects by reducing oxidative stress, inflammation, and excitotoxicity in the brain. Activation of CB1 receptors by endocannabinoids has been shown to promote neuronal survival and reduce the accumulation of toxic proteins associated with neurodegenerative diseases.

Metabolic Syndrome and Diabetes

Endocannabinoids have also been implicated in the regulation of metabolic processes and energy balance. Research suggests that dysregulation of the ECS may contribute to the development of obesity, insulin resistance, and type 2 diabetes. By modulating the activity of the ECS, endocannabinoids can potentially influence glucose homeostasis, lipid metabolism, and energy expenditure, thereby affecting the progression of metabolic syndrome and diabetes.

Conclusion

The role of endocannabinoids in regulating chronic diseases is a promising area of research, offering new insights into potential therapeutic targets. By modulating inflammation, immune response, neuroprotection, and metabolic processes, endocannabinoids hold the potential to improve the quality of life for individuals suffering from chronic conditions. However, further research is needed to fully understand the complexities of the endocannabinoid system and develop targeted therapies that harness its potential without relying on CBD or other exogenous cannabinoids. If you wish to help support people with chronic conditions, you can donate here to CISFA UK via PayPal.

[alrederedmixedmedia]

Alredered is celebrating #ChronicDiseaseDay to-day

On July 10 we spread awareness on Chronic Disease Day to educate and advocate for people who live with a chronic health conditions every day. Our hope is to raise awareness to be supportive for anyone suffering from a chronic disease.

[damagedparents]

I have CRPS which is a very debilitating and painful syndrome. I never know what symptom is going to show up. CRPS can lead to depression, anxiety, insomnia and more quite simply because one never knows which symptom is going to be most prevalent. Most people don't have to figure out how to make friends with pain. But if you have pain it is always better to listen to it and give it space to exist. #CRPS #chronicpain #celebrateeveryday #chronicdiseaseday #disability #disabilitypride #pride #selflove #disabilitypride2023

[opticalforum]

I stand strong for You #ChronicDiseaseDay #Optometry #OpticalForum https://www.instagram.com/p/Cf1-FMHtWLJ/?igshid=NGJjMDIxMWI=

[sfc-paulchambers]

• @natdaycal JULY 10, 2022 NATIONAL CLERIHEW DAY | NATIONAL KITTEN DAY | NATIONAL PINA COLADA DAY | CHRONIC DISEASE DAY The kitten named Gwendolyn Baker🐱 Is a tremendous troublemaker😼 She eats food that isn't hers😸 And everywhere sheds her furs!🤧 #NationalClerihewDay #NationalKittenDay #NationalPinaColadaDay #ChronicDiseaseDay Did you know tomorrow never comes? That is why we Celebrate Every Day. Tag @NatDayCal with your favorite way to celebrate the over 1,500 National Days. (at Middle Tennessee Area) https://www.instagram.com/p/Cf1uoh-umZt/?igshid=NGJjMDIxMWI=

[tigerlivyproject]

Tiger Livy is all about pediatric chronic illness and on #chronicdiseaseday we want to repost a brilliant insight from @fightlikeawarrior • “Chronic diseases account for 7 of the top 10 causes of death in the United States & 90% of our annual healthcare spending. Today is #ChronicDiseaseDay and we’re partnering with @gooddaysorg to raise awareness about issues that impact the chronic disease community so we can better support individuals with chronic conditions and invisible illnesses!⁣ ⁣ What is Chronic Disease Day all about? It brings together state and city governments, national patient advocacy groups and local communities to share actionable resources and support the chronic disease community.⁣ ⁣ Learn how to get involved at ChronicDiseaseDay.org ✅⁣” ⁣. Please go check them out today and get your order of Tiger Livy in English or Spanish on Amazon today! #curejm #autoimmunedisorder #pediatrics #illness #chronicillness #autoimmune #disorder #healing #wellness #inspiration #inclusion, #healing #pediatrics #childlife #mentalhealth #pediatricnurse #grandparent #parenting #support #inspiration #heal #brave #representation #childlife #sick #coping #survive #acceptance #community #childrensliterature #teacher #chronicillness #childlifespecialist https://www.instagram.com/p/CCeoHGZJjry/?igshid=1tks8hcezhrpx

[kidneystories2013]

Chronic Disease Coalition @ChronicRights Hey @kidneystories- #virtualhug to you on this #ChronicDiseaseDay - Thanks for all that you do to increase awareness 365 days a year! #ChronicTogether HEY THAT'S ME! (at Hammond, Indiana) https://www.instagram.com/p/CCeG3mljL47/?igshid=e27xyne0d0w9

[thechronicbellydancer]

7 out of 10 people in The United States has a #chronicdisease / #chronicillness ...I am 7 out of 10. | #chronicdiseaseday 07°10°2019 | #autoimmunesdisease #invisibleillness #chronicillness #chronicpain #crohnsdisease #ulcerativecolitis #irritableboweldisease #thechronicbellydancer #chroniccommunity #ibdawareness #crohnsawareness #spoonie #crohnie (at Los Angeles, California) https://www.instagram.com/p/BzwjCrNFyNL/?igshid=8fl2ji23bo31

[kidneystories2013]

@chronicrights On Chronic Disease Day, I thank my all of my fellow Advocates including @mary_baliker, Mary Baliker for advocsting for all of us afflicted with Chronic Diseases. #ChronicDiseaseDay #ChronicTogether #ChronicDiseaseCoalition (at Hammond, Indiana) https://www.instagram.com/p/CCeGfQdD_DU/?igshid=7xhpnsk389xu

[kidneystories2013]

Fighting Fiercely @FightFierceEndo Today is Chronic Disease Awareness Day. According to the National Center for Chronic Disease Prevention and Health Promotion, 6 in 10 adults in the U.S. have a chronic disease and 4 in 10 have two or more! #ChronicDiseaseDay #ChronicTogether (at Hammond, Indiana) https://www.instagram.com/p/CCeFm3ED5Xb/?igshid=1jc1ycedykidb

[kidneystories2013]

Chronic Disease Coalition @ChronicRights Hey - @morse_tami #virtualhug to you on this #ChronicDiseaseDay - Thanks for all that you do to increase awareness 365 days a year! #ChronicTogether (at Hammond, Indiana) https://www.instagram.com/p/CCeDjPsj-j3/?igshid=1m8mlc1tqq5a8

[kidneystories2013]

@chronicrights On Chronic Disease Day, I thank all of our leaders for advocating for all of us afflicted with Chronic Diseases. Samantha Siegner, Dave Snepp, Bryan Dorn, Erin Foote Morgan, Scott Brunn, Kailey Fisucaro & Lindsey. #ChronicDiseaseDay #ChronicTogether #ChronicDiseaseCoalition (at Hammond, Indiana) https://www.instagram.com/p/CCeDXSiDHh-/?igshid=hikx54lzzz21

[kidneystories2013]

@chronicrights On Chronic Disease Day, I thank my partner in crime Curtis for chatting & advocating for all of us afflicted with Chronic Diseases. #ChronicDiseaseDay #ChronicTogether #ChronicDiseaseCoalition (at Hammond, Indiana) https://www.instagram.com/p/CCeB4M8jscu/?igshid=p78ri6o1zj7u

[kidneystories2013]

@chronicrights On Chronic Disease Day, I thank you Kat for advocating for all of us afflicted with Chronic Diseases. #ChronicDiseaseDay #ChronicTogether #ChronicDiseaseCoalition (at Hammond, Indiana) https://www.instagram.com/p/CCeBm71DmAp/?igshid=13opbo0572vlh

[kidneystories2013]

@chronicrights On Chronic Disease Day, I thank you Libby for advocating for all of us afflicted with Chronic Diseases. #ChronicDiseaseDay #ChronicTogether #ChronicDiseaseCoalition (at Hammond, Indiana) https://www.instagram.com/p/CCeBd4wDVDA/?igshid=1esgqh0pozzbk

[kidneystories2013]

@chronicrights Today is #ChronicDiseaseDay – a day to reflect on the impact of #ChronicIllness on our communities. Charitable assistance organizations provide financial support to patients living with chronic diseases, helping thousands of patients access essential medicine. #ChronicTogether, #ChronicDiseaseDay #ChronicDiseaseCoalition (at Hammond, Indiana) https://www.instagram.com/p/CCeA944jyVd/?igshid=tj7dtdu9z5vf