#bydureon weight loss

[coppercorn-and-cauldron]

I saw your post about IIH from October. I have IIH too, diagnosed in 2020. I was considering a shunt, but decided to try exenatide as a last resort since the US govt gave it orphan drug status for IIH and clinical trials were promising. I take Bydureon injections once a week (4 months now) and it has done wonders for me - I can work full time and I'm planning on going back to school. it's expensive and I had to jump through a lot of hoops, but it's made my life liveable. my IIH is still there but I can function now.

Exenatide is usually sold as Byetta in NZ.

And I don't qualify for it under our health system unless I also have diabetes or prediabetes. I cannot afford it unfunded even if I find a Doc willing to try it as an off-label use med for IIH.

What's funny (read: infuriating) is that if I asked about it in relation to weight loss it's possible that I might be fully funded under that category.

I am trialing a CBD product currently and it seems to reduce my tinnitus, eye pain, head, neck, and upper back pain, light sensitivity, etc so it might be working to both reduce pain and pressure. And I've managed to finish 3 hardcopy books and a few ebooks in the last fortnight or so.

But I'm not anywhere near being able to study or work, yet.

Once this trial is finished it (beyetta) might be my step, treatment-wise.

[blsm-m]

Glucagon-like peptide-1 (GLP-1) is a hormone that regulates blood sugar levels. But sometimes, especially if you have diabetes, your body needs some extra help from the GLP-1 hormone. This is where natural alternatives to GLP-1 come in. They act like a sidekick, supporting your body's natural rhythms and helping to keep blood sugar levels normal. While much of the science continues to develop, let’s explore natural GLP-1 agonists and how they can complement your health journey. Does natural GLP-1 exist? The answer is not simply "yes" or "no." Some foods may make you feel fuller longer and slow digestion (like GLP-1 drugs), but they don't necessarily result in the same rapid weight loss. GLP-1 is a hormone produced naturally in the body. Intestinal cells secrete it to regulate blood sugar levels. GLP-1 tells the body to produce insulin, which tells cells to absorb sugar and produce energy. Also Slows digestionIt reduces hunger, promotes metabolic health and aids in weight loss. It directs the blood sugar orchestra and keeps it in harmony. The body is natural Adequate GLP-1 This is to keep your blood sugar in check, but if you have diabetes or insulin resistance, that may not be enough. Diabetes A condition in which blood sugar levels rise because the body can't produce or properly use insulin, which cells need to absorb sugar for energy. Insulin resistance It occurs when cells don't respond well to insulin. Without insulin, cells can't absorb sugar, leading to hyperglycemia. Therefore GLP-1 receptor agonists When taken into the body, they mimic the natural GLP-1 hormone and act as enhancers, increasing GLP-1 levels in the body and controlling blood sugar levels. They stimulate insulin release and promote insulin sensitivity. This allows your cells to absorb glucose, lowering your blood sugar levels, making you feel fuller for longer and suppressing your appetite. Several GLP-1 agonists The following medicines are available: Exenatide (Vietta, Bydureon) Liraglutide (Victoza, Saxenda) Dulaglutide (Trulicity) Weight loss drugs Semaglutide (Wegovi However, if GLP-1 medications don't suit you, you can consider incorporating certain foods into your diet that act as natural GLP-1 agonists and help control blood sugar levels. According to Stephanie Nelson, a registered dietitian at MyFitnessPal, "While dietary changes won't have the same effect as GLP-1 drugs, they will make you feel fuller for longer and slow down your digestion. And we're still learning a lot, so we'll know more as time goes on." Whatever the outcome of future research on natural GLP-1 agonists, simple changes to your diet and lifestyle could make a big difference in your overall health in the long run. So let’s take a look at some natural ingredients that can boost your GLP-1 levels. Top 5 Foods and Supplements to Increase GLP-1 Naturally Here are some natural GLP-1 agonists that can give your body that extra support to improve blood sugar control. 1. Eggs and a protein-rich breakfast Recent Research Consuming foods rich in protein and calcium for breakfast has been shown to promote the release of GLP-1 and aid in weight loss. Research into the potential link between protein-rich foods and GLP-1 release is ongoing, but the evidence is still limited. Still, adding protein to your breakfast has plenty of health benefits, so whether you naturally promote GLP-1 release or not, start your day with eggs and other protein-rich foods. Breakfast staples like eggs, milk, peanut butter toast, protein smoothies, quinoa porridge, and Greek yogurt with fruit provide essential nutrients and support healthy living, while also helping to regulate blood sugar levels and keep you fuller for longer. 2. Nuts as a nutritious snack Nuts are a delicious, nutritious snack that promotes a healthy diet. Nuts are said to boost GLP-1, but what do we actually know? The evidence is

conflicting: the study Nuts have been shown to increase GLP-1 levels, but another study Consuming nuts has been shown to decrease GLP-1 levels. Larger studies in different populations are needed to determine for sure whether nuts increase GLP-1. The good news? Nuts are a great source of protein, healthy fats, and dietary fiber. Eating nuts improves the quality of your diet, and a healthy diet leads to weight loss and a healthy weight. So, regardless of their effect on GLP-1, adding nuts to your diet is likely a nutritional boost. 3. High-Fiber Grains Stimulate GLP-1 Production Take it every day High Fiber Grains Stimulates natural GLP-1 production: Grains rich in soluble fiber, such as oats, barley, and rye, may promote the release of GLP-1, which may help manage blood sugar levels, improve insulin sensitivity, and promote digestive health. Replacing refined grains with high-fiber whole grains can also help. Weight loss Travel and improve your overall health. Many people believe they are meeting the recommended amount of dietary fiber, but in fact they are not getting enough. Most adults Women should aim to consume 25 grams of fiber per day, and men 38 grams. To get a better idea of ​​how much fiber you're actually consuming, track your food intake with MyFitnessPal. Tracking your food can help you reach your nutritional goals. 4. Magnesium supplements to stabilize blood sugar levels magnesium is an essential mineral that has many health benefits. But most importantly, it helps maintain healthy blood sugar levels. In a study of diabetic rats, Magnesium supplements It promotes the release of GLP-1, regulates glucose metabolism, and improves insulin sensitivity, but there is a lack of human studies on the subject. Still, magnesium is an important nutrient that has health benefits beyond its potential effect on GLP-1 release. You can increase your dietary magnesium intake by enjoying foods such as spinach, leafy greens, nuts, peas, beans, whole grains and seeds, or by taking a magnesium supplement. 5. Eat lean protein to increase GLP-1 and maintain muscle mass Lean proteins such as chicken, fish, and tofu may help boost GLP-1 levels. Protein-rich foods It is rich in amino acids that promote the release of GLP-1, which may help preserve muscle mass and aid in weight management. Adding lean protein to your diet may help boost natural GLP-1 levels, stabilize blood sugar levels, and keep muscles healthy. Conclusion Including eggs, nuts, high fiber grains, magnesium supplements and lean protein in your diet can help support your overall health. These nutrient-rich foods contribute to a balanced diet and can help support the release of GLP-1, helping you maintain a healthy weight. Although we are still studying how these nutrient-rich foods affect GLP-1, we know that they can improve the quality of your diet, leading to weight loss and maintaining a healthy weight, so there’s no harm in including them in your diet. Food tracking tools My Fitness Pal Adopting a holistic approach to health is key to supporting your health journey. By making conscious food choices and incorporating natural GLP-1 alternatives, you can create a sustainable lifestyle that prioritizes your health. Whether your goal is to lose a little weight or simply improve your health, remember that small changes add up to big results, so start your journey to a healthier you, one step at a time.

[novaglobalhealthcare]

What Are My Options for Type 2 Diabetes Medications?

There are different types, or classes, of medications that work in different ways to lower blood glucose (also known as blood sugar) levels. Some options are taken by mouth and others are injected. Some of the commonly used classes of non-insulin medications include:

Metformin

Dipeptidyl peptidase 4 (DPP-4) inhibitors

Glucagon-like peptide 1 (GLP-1) and dual GLP-1/gastric inhibitory peptide (GIP) receptor agonists

Sodium-glucose cotransporter 2 (SGLT2) inhibitors

Sulfonylureas

Thiazolidinediones (TZDs)

Metformin

Metformin (Glucophage) is classified as a biguanide medication and is the only available medication in this class. Metformin lowers blood glucose levels primarily by decreasing the amount of glucose produced by the liver. Metformin also helps lower blood glucose levels by making muscle tissue more sensitive to insulin so blood glucose can be used for energy.

It is usually taken two times a day. A side effect of metformin may be diarrhea, but this is improved when the drug is taken with food.

DPP-4 Inhibitors

DPP-4 inhibitors help improve A1C (a measure of average blood glucose levels over two to three months) without causing hypoglycemia (low blood glucose). They work by preventing the breakdown of naturally occurring hormones in the body, GLP-1 and GIP. These hormones reduce blood glucose levels in the body, but they are broken down very quickly so it does not work well when injected as a drug itself.

By interfering in the process that breaks down GLP-1 and GIP, DPP-4 inhibitors allow these hormones to remain active in the body longer, lowering blood glucose levels only when they are elevated. DPP-4 inhibitors do not cause weight gain and are usually very well tolerated.

There are four DPP-4 inhibitors currently on the market in the U.S.:

Alogliptin (Nesina)

Linagliptin (Tradjenta)

Saxagliptin (Onglyza)

Sitagliptin (Januvia)

GLP-1 and Dual GLP-1/GIP Receptor Agonists

As noted in the description for DPP-4 inhibitors, GLP-1 and GIP are natural hormones in the body that help maintain glucose levels. Use of GLP-1 and dual GLP-1/GIP receptor agonists is another strategy to help use these hormones to improve blood glucose management in people with type 2 diabetes.

These medications have similar effects to the GLP-1 and GIP produced in the body but are resistant to being broken down by the DPP-4 enzyme. These medications can result in large benefits on lowering blood glucose and body weight. Some agents in this class have also been shown to prevent heart disease. Most of these medications are injected, with the exception of one that is taken by mouth once daily, called semaglutide (Rybelsus).

Injectable GLP-1 receptor agonists currently on the market include:

Dulaglutide (Trulicity)

Exenatide (Byetta)

Exenatide extended-release (Bydureon)

Liraglutide (Victoza)

Lixisenatide (Adlyxin)

Injectable semaglutide (Ozempic)

One dual GLP-1/GIP receptor agonist is currently on the market called tirzepatide (Mounjaro). How often you need to inject these medications varies from twice daily to once weekly, depending on the medication. The most common side effect with these medications is nausea and vomiting, which is more common when starting or increasing the dose.

SGLT2 Inhibitors

Glucose in the bloodstream passes through the kidneys where it can either be excreted in the urine or reabsorbed back into the blood. Sodium-glucose cotransporter 2 (SGLT2) works in the kidney to reabsorb glucose. A new class of medication, SGLT2 inhibitors, block this action, causing excess glucose to be eliminated in the urine.

By increasing the amount of glucose excreted in the urine, people can see improved blood glucose, some weight loss, and small decreases in blood pressure. Bexagliflozin (Brenzavvy), canagliflozin (Invokana), dapagliflozin (Farxiga), and empagliflozin (Jardiance) are SGLT2 inhibitors that have been approved by the Food and Drug Administration (FDA) to treat type 2 diabetes. SGLT2 inhibitors are also known to help improve outcomes in people with heart disease, kidney disease, and heart failure.

For this reason, these medications are often used in people with type 2 diabetes who also have heart or kidney problems. Because they increase glucose levels in the urine, the most common side effects include genital yeast infections.

Sulfonylureas

Sulfonylureas have been in use since the 1950s and they stimulate beta cells in the pancreas to release more insulin. There are three main sulfonylurea drugs used today, glimepiride (Amaryl), glipizide (Glucotrol and Glucotrol XL), and glyburide (Micronase, Glynase, and Diabeta). These drugs are generally taken one to two times a day before meals.

All sulfonylurea drugs have similar effects on blood glucose levels, but they differ in side effects, how often they are taken, and interactions with other drugs. The most common side effects with sulfonylureas are low blood glucose and weight gain.

TZDs

Rosiglitazone (Avandia) and pioglitazone (Actos) are in a group of drugs called thiazolidinediones. These drugs help insulin work better in the muscle and fat and reduce glucose production in the liver.

A benefit of TZDs is that they lower blood glucose without having a high risk for causing low blood glucose. Both drugs in this class can increase the risk for heart failure in some individuals and can also cause fluid retention (edema) in the legs and feet.

[mandyjane-lifedesign]

Diabetics face critical medicine shortages as their drugs are snapped up for weight loss treatment

Many of Britain’s 4.3 million registered diabetics face a critical medication shortage as their treatments are snapped up by dieters trying the latest trend – weight loss jabs. A leading testing expert says the UK’s diabetes epidemic means that key drugs should be saved for patients who critically depend on them. Wonder weight loss treatment drugs ‘Wonder’ weight loss drugs, such as Wegovy, have hit the headlines in recent weeks. They can help people shed 10%-15% of their bodyweight, largely by supressing their appetite. However, some of these weight loss jabs are based on semaglutide, first developed for treating type 2 diabetes. This means the boom in demand for ‘magic bullet’ weight loss jabs is contributing to a major shortage in key diabetes medication, says a leading expert. Leading blood testing expert, Dr Avinash Hari Narayanan (MBChB), Clinical Lead at London Medical Laboratory, says: ‘There is now a global shortage of semaglutide-based drugs for treating diabetes. Key among these is Wegovy’s sister drug, Ozempic, used by the NHS as a treatment for managing blood glucose levels in people with type 2 diabetes, which accounts for 90% of all diabetes cases in the UK. This will result in both acute and chronic medical complications if left unmanaged. ‘Both Wegovy and Ozempic are produced by the Danish pharmaceutical giant Novo Nordisk. The problem is that Ozempic has increasingly been prescribed off label (outside of its approved licence) for weight loss as an alternative to Wegovy. Now Novo Nordisk is warning of shortages of Ozempic stretching into 2025. ‘Ozempic and Wegovy became a social media phenomenon earlier this year as a weight loss cure, with demand for semaglutide spiralling after celebrity endorsements. That’s not what Ozempic was intended for and has resulted in demand far outstripping supply. Now Novo Nordisk’s official weight loss drug, Wegovy, is finally available in the UK on the NHS and as a private prescription. However, though this will relieve the demand on critical Ozempic stocks, supplies of all semaglutide-based treatments remain limited. Patients being treated for type 2 diabetes need to know that there are sufficient stocks of this treatment and, if not, patients need a plan to mitigate against supply disruptions. ‘Novo Nordisk now has a market cap of $419.79bn, making it the world's 17th most valuable company.  Astonishingly, the market value of the Danish company has exceeded the size of Denmark’s domestic economy (£395.40bn). We are keen for Novo Nordisk to continue concentrating on the production of vital diabetes treatments, over other semaglutide-based products. The company has stated that it will prioritise treatments for existing patients, rather than focusing on introducing new people to Wegovy weight loss treatments. ‘We support Diabetes UK in urging clinicians to follow Department for Health and Social Care guidance, which states clinicians should not prescribe these drugs outside of their licensed use until the supply issues are rectified. ‘It’s not only in the UK that restricted supplies are causing problems; there’s a worldwide shortage. America’s FDA lists Wegovy and certain Ozempic dosages as being in short supply. So too does Australia’s Therapeutic Goods Administration (TGA), which says supplies of Ozempic will remain limited to diabetes treatments only until at least the end of December 2023, and that patients prescribed Ozempic for other conditions should contact their doctor to have their treatment reassessed. ‘The shortage doesn’t only impact on semaglutide-based drugs. All “GLP-1 analogues”, as this family of drugs are known, are in short supply. These include the brands Ozempic, Rybelsus, Trulicity, Victoza, Saxenda, Byetta and Bydureon. This appears to be pan-market disruption, complicated by exceeding demands. ‘All these drugs: - signal to your body to make more insulin (the hormone that controls the amount of sugar in your blood) - reduce the amount of glucose (gluconeogenesis) that your liver makes - slow down the digestion of food, so that it takes longer for your body to absorb the sugar from meals - reduce your appetite by increasing satiety ‘It’s the final effect that has created this unexpected surge in demand. However, there is some welcome news of another GLP-1 analogue drug just about to reach the UK. The National Institute for Health and Care Excellence (NICE) has approved the use of tirzepatide (brand name Mounjaro) for treating type 2 diabetes in England and Wales. Supplies of this new drug should come on stream within three months. ‘Again, it’s vital this new medication is prioritised as a further treatment for type 2 diabetes, rather than for other purposes. It, too, is likely to be in hot demand by people seeking to lose weight the easy way. In the US, clinical weight loss trials show Mounjaro is even more effective than Ozempic, with patients achieving 26.6% weight loss over 84 weeks. ‘By 2030, diabetes cases in the UK will have risen by 50% compared to 2007 levels, according to Diabetes UK. Unmanaged or undiagnosed diabetes is one of the leading causes of mortality. Diabetes is usually linked to factors such as weight, lifestyle, age and family history. One in ten people will have diabetes by the end of the next decade, and one in three will be at a much increased risk of developing it. The truly frightening thing is that it is quite common for people to have diabetes and not know about it. ‘Fortunately, there is a simple blood test that will categorically confirm whether or not you have type 2 diabetes – even in the earliest stages, long before any symptoms have developed. This home test checks your levels of HbA1c. This biomarker is used to confirm whether you have (or are at risk of developing) diabetes. For anyone who already knows they have diabetes, regular HbA1c checks are also essential to monitor progress. ‘London Medical Laboratory’s “Diabetes - Diagnosis and Monitoring test” can be taken at home through the post, or at one of the many drop-in clinics that offer these tests across London and nationwide in over 95 selected pharmacies and health stores. For full details, see: https://www.londonmedicallaboratory.com/product/diabetes-check Photo by Total Shape on Unsplash Read the full article

[tallmantall]

#JamesDonaldson On #MentalHealth – Ozempic, Other GLP-1 #Drugs Under Safety Review For Risk Of #SuicidalThoughts

Ozempic and other GLP-1 drugs are currently under safety review in several countries after a small number of cases have reported an increase in #suicidalthoughts while taking the medications - GLP-1 drugs like Ozempic, Wegovy, and Trulicty are under safety review following reports that the medications may cause #suicidalideation. - The risk of #suicidalthoughts is not currently listed as a potential side effect of GLP-1 drugs. - A handful of cases have reported #suicidalthoughts and #self-harming #behavior in people using GLP-1 medications. - Research shows no evidence of a direct cause between GLP-1 #drugs and #suicidalideation. Semaglutide (sold under the brand names Ozempic and Wegovy) as well as other GLP-1 medications that can aid with #weightloss are currently under safety review for the potential risk of increasing #suicidalthoughts. Following a relatively small number of cases reporting #suicidalthoughts and #self-harming #behavior in people using GLP-1 receptor agonists, agencies in Canada, Europe, and the United Kingdom are assessing whether the side effect is caused by the medication or is associated with underlying conditions. Suicidal thoughts are not currently listed as a potential side effect of Ozempic, according to the U.S. Food and Drug Administration’s drug label and the EU product information. Along with Ozempic and Wegovy, here are some other GLP-1 #drugs currently under review: - AstraZeneca’s medication exenatide (Bydureon) - Eli Lilly’s dulaglutide (Trulicity) - Sanofi’s lixisenatide - Sanofi’s Soliqua “GLP-1 receptor agonists have been used to treat type 2 diabetes for more than 15 years and for treatment of #obesity for 8 years, including Novo Nordisk products such as semaglutide and liraglutide that have been on the market for more than 10 years,” Novo Nordisk, Ozempic’s manufacturer, said in a statement. Semaglutide is the active medical ingredient in Ozempic. “The safety data collected from large clinical trial programs and post-marketing surveillance have not demonstrated a causal association between semaglutide or liraglutide and suicidal and #self-harming thoughts,” the company said. Ozempic and other GLP-1 drugs are not directly linked with #suicidalideation #James Donaldson notes:Welcome to the “next chapter” of my life… being a voice and an advocate for #mentalhealthawarenessandsuicideprevention, especially pertaining to our younger generation of students and student-athletes.Getting men to speak up and reach out for help and assistance is one of my passions. Us men need to not suffer in silence or drown our sorrows in alcohol, hang out at bars and strip joints, or get involved with drug use.Having gone through a recent bout of #depression and #suicidalthoughts myself, I realize now, that I can make a huge difference in the lives of so many by sharing my story, and by sharing various resources I come across as I work in this space.  #http://bit.ly/JamesMentalHealthArticleFind out more about the work I do on my 501c3 non-profit foundationwebsite www.yourgiftoflife.org Order your copy of James Donaldson's latest book,#CelebratingYourGiftofLife: From The Verge of Suicide to a Life of Purpose and Joy www.celebratingyourgiftoflife.com “At this time, GLP-1 drugs like Ozempic have not been directly linked or even evaluated for a potential link to #suicidalideations,” said Dr. Mirela Loftus, PhD, medical director for Newport Healthcare. “There has been no causal effect documented in any literature,” said Dr. Steven Batash, FACG, a gastroenterologist currently affiliated with NYU Medical Center, Lenox Hill Hospital, and NewYork-Presbyterian Hospital to Healthline. Batash provides endoscopic weight loss procedures or non-surgical #weightloss. He adds that in his practice, he hasn’t come across anyone experiencing #suicidalthoughts after taking a GLP-1 receptor agonist. “The manufacturers deny that #suicidalthoughts were reported during their trials,” said Dr. Jodie Pepin, clinical pharmacy program director at Harbor Health and an assistant professor of pharmacy at the University of Texas in Austin. “As far as the newly reported #suicidalthoughts possibly related to the GLP-1s, there will have to be an abundance of evidence that proves causation, not just correlation,” she said. Pepin also explains that millions of people have taken these medications, and the more people who take them, the more likely these side effects will show up. “The numbers of #suicidalthoughts are relatively small compared to the number of prescriptions written for these medications,” she adds. “The population who takes these medications have comorbidities or underlying conditions that may influence their response to drugs,” she tells Healthline. Examples include pre-existing #mentalhealthconditions like #depression or comorbidities like heart disease, which can often be associatedTrusted Source with #depression, she adds. “These responses may have little or nothing to do with the medication they are taking,” she said. What to know before taking GLP-1 medications Be sure to discuss your concerns about side effects from GLP-1 drugs with your #doctor. GLP-1s are intended for people with higher BMIs GLP-1 medications mimic the hunger hormones that suppress appetite and promote satiety or a feeling of fullness. “We have to remember that medications like Ozempic and Wegovy are meant for people who are over a BMI of 30 or 27 with one comorbidity,” said Batash. “These medications are frequently used off-label for people who are below a 27 BMI,” he adds. “Please remember that these medications got approved for weight loss only recently and we don’t know long-term side effects of these medications and dosages that are currently taken for weight loss,” he told Healthline. Black box warnings provide crucial safety information about GLP-1 drugs Pepin said the safety warnings around the GLP-1 drugs are very explicit in the prescribing information. “A Black Box Warning, or the most serious type of warning that can be included in prescribing information, is common among these medications,” she said. The FDA warning is to avoid these GLP-1 agonist medications if you have a history of or a family history of: - medullary thyroid cancer because the GLP-1s may cause an increased risk of this type of cancer - pancreatitis, so it is recommended to avoid the #drugs in people with a history of pancreatitis or at risk of pancreatitis “Side effects of these medications can be pretty severe, and if your quality of life is affected, you should look for other methods that can help you lose weight,” said Batash. GLP-1s are not a sustainable long-term solution for #weightloss Batash said these medications are not a long-term solution for #weightloss unless you are willing to commit to a lifetime of taking them. He also said you will need to consider the cost of medication use over a long period of time, asking yourself if it makes sense to spend large amounts of money to use medication that may not be medically necessary. Pepin agrees. “People should consider the cost of the #drugs because they are very expensive, particularly when taken for #weightloss.” “Very few, if any, insurance companies will pay for them,” she said. What to do if you have #suicidalthoughts while taking Ozempic or other GLP-1 #drugs “You should always be aware and be well-informed of all possible side effects of medications you are taking,” said Batash. “It is important to be under medical supervision while taking any of the medications but especially ones that can affect your #mentalhealth,” he added. “If you feel like you might be experiencing any of the side effects listed for medications that you are taking, it is important to inform your medical provider immediately.” There are a few more things to consider if you’re taking a GLP-1 medication and experiencing suicidal thinking. First, Pepin recommends the person call a #suicidehotline or their #therapist if they have one, immediately. If you or your loved one experiences #suicidalthoughts, thoughts of #self-harm, or extreme #hopelessness, call the #NationalSuicidePreventionLifeline, for free and confidential support at #988. Then, Pepin suggests that the person contact their provider as soon as possible and have a discussion regarding the continuation or discontinuation of the #drug. “The provider can look at the individual’s health history and comorbidities to determine, if in their clinical judgment, it is prudent to continue the medication or not,” she said. “A risk-benefit analysis should also be done to aid in this situation,” said Pepin. Batash echoes this, noting that it’s important for any #physician who is prescribing these medications to do a screening. “A #patient who has history of having #mentalhealthissues or experience #suicidalthoughts should not be prescribed GLP-1 agonists for #weightloss or #diabetes and should be strongly cautioned about potential side effects,” said Batash. Read the full article

[geeksentiments-blog]

Check out https://bydureonguide.com/does-bydureon-cause-weight-loss/ about bydureon for weight loss in non diabetics.

[foreveralonelife]

Can Bydureon make you lose weight even if you are non-diabetic? Find out here:

https://bydureonguide.com/does-bydureon-cause-weight-loss/

[barnythedinosaur]

is it possible to lose weight with bydureon? Find out here at https://bydureonguide.com/does-bydureon-cause-weight-loss

[bydureonpen14-blog]

The Ultimate Guide To Bydureon Pen For Diabetes

Are you someone who has had diabetes for several years and you simply can't control your sugar anymore on oral medicines? Diabetes is a progressive disease and sometimes adjustments in medicine regimens need to be made to help control blood sugar.

What Is Bydureon?

Bydureon, is a long-acting form of the medication Byetta that is given once per week. Bydureon is a GLP-1 (glucagon-like peptide 1) agonist that stimulates insulin secretion when it comes into contact with glucose.

It has also been shown to preserve beta cell function (beta cells make insulin) and has been proven to promote weight loss by delaying gastric emptying and increasing feelings of fullness. Studies have shown that people taking Bydureon lose an average of about five pounds by month six of taking the medication and have been shown to keep it off by year three. Learn more about bydureon insulin pen.

Blood Sugar Control: While clinical trials have shown that treatment with Bydureon can help to reduce A1c by about 1.5 percent, Bydureon is not used as a first-line diabetes treatment. Instead, it is typically used as a second or third agent in combination with metformin or a sulfonylurea.

Taking Bydureon?

Previously, Bydureon was only available using a syringe that was rather long and thick. Although the injection was only once per week, some people complained of discomfort. However, now Bydureon is available for use via pen. The pen is likely to be more comfortable and easier to use than the syringe.

Who Is a Candidate for Bydureon?

Discuss with your healthcare provider if you are a candidate for Bydureon. Bydureon is not meant to be used as a weight loss drug and is typically used in conjunction with other diabetes medicines. If you are someone with type 2 diabetes whose blood sugars are not at goal and can afford to lose some weight than Bydureon might be an option for you. Visit this website to get more info about ultimate guide to Bydureon pen.

Who Should Not Take Bydureon?

In animal studies, Bydureon caused rats to develop tumors of the thyroid gland. Therefore, Bydureon is contraindicated in patients with a personal or family history of medullary thyroid cancer (MTC) and in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). People with sensitivity to exenatide or to any product components should also not take Bydureon.

Side Effects?

Because Bydureon delays gastric emptying, the most common side effects include nausea and vomiting. Nausea commonly happens when first starting the medication and decreases over time when the body gets used the medication. Other side effects include headaches, diarrhea, redness at the injection site.

[bydureonbcisesideeffects-blog]

Everything You Should Know About The Dangers Of Bydureon

A bydureon pen is a pen pre-filled, single used pen injector, its a new treatment for type 2 diabetes and works by helping the body release its own insulin when needed to reduce glucose present in the blood.

It is a treatment of its kind as it has a unique continuous release delivery system under the skin. Each dose is made of microspheres (tiny particles) that gradually release the medicine into your body.

How To Use Bydureon Pen?

Type 2 diabetes is a serious disease as you know affecting everyone from all walks of life from children to the adults and therefore needs proper management with the use of bydureon pen which is a medication that you only take once in a week and eliminates the need for you to transfer the medication between vial and syringe.

Its indicated as an adjunct to exercise and diet to improve glycemic in adults with type 2 diabetes mellitus.

One dose lasts for seven days with each dose providing a gradual increase in the amount of exenatide in your blood as it is released from the tiny particles.

Your diabetes specialist or doctor will guide you on how to administer bydureon correctly before you use it for the first time.

Dangers Of Bydureon:

This is a prescription drug used in the treatment of type two diabetes mellitus.

It is usually injected under the skin and aids your body in the production and release of insulin when required.

It also inhibits the liver from producing excess amounts of sugar.

Like any other pharmaceutical product, it may cause a few after effects and reactions.

Possible Response To Bydureon:

Bydureon may cause thyroid tumors. A patient can develop thyroid tumors while on Bydureon.

Anaphylaxis From Some Of The Ingredients:

This is a severe allergic reaction. One may experience difficulty breathing, swelling of the throat and airway and skin rashes.

Kidney Failure:

Symptoms of kidney failure include; swelling, confusion, lethargy, weakness, shortness of breath and abnormal heart rhythms.

Stomach Problems:

Inform your physician if you notice any stomach problems such as slowed emptying, constipation, and diarrhea.

Pancreatitis:

This illness is inflammation of the pancreas. It is characterized by the following symptoms; upper abdominal pain that goes through to the back, abdominal pain that worsens after meals, fever, rapid pulse, nausea, vomiting, unintentional weight loss, abdominal tenderness and oily stool.

Injection Site Reactions:

This is damage to the skin around where the drug is usually administered. These reactions are not necessarily caused by allergens.

Hypoglycemia:

The use of by duration in addition to other similar medications greatly increases one’s chances of getting low blood sugar.

Weight Loss:

Bydureon has been seen to promote weight loss in those who are taking it.

Other common dangers of this drug are; diarrhea, headache, vomiting, loss of appetite, hair loss, constipation, and indigestion

Click here for more info about Common side effects https://bydureonguide.com/side-effects/ of bydureon pen

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Benefits Of Selecting The Right Weight Loss Program For Quick Weight Loss!

The best thanks to changing state isn't to crash diet or have bursts of exercise, however, to form slow changes. The most effective thanks to making these changes and follow them are to form a weight loss program. This will be accustomed to launched your targets, however, you're visiting come through them, and changes as they occur.

By employing a weight loss program you'll implement these changes and follow them. It should conjointly work best if you write you're set up down, keeping a note of your targets, changes in weight and achievements to assist you to remain on course. While you'll not see any immediate changes, persist with it. Don't let any weight gain place you off, and instead, take a look at your program and see if something must modification, like increasing your activity levels. And once you reach your goals celebrate by treating yourself to one thing like an evening out or a replacement outfit to form your weight loss even sweeter.

Another facet of your weight loss program can be a food diary. By writing down all the food and drink you're taking in throughout the week you may notice it easier to determine wherever you're going wrong. You'll review the diary at the top of every week to urge a clearer image of simply what quantity calories you actually are intense. If your diet appearance healthy and however you continue to aren't losing any weight, you'll have to take a look at your portion sizes to form positive you're merely not uptake an excessive amount of. Click here for more info about the truth about losing weight with the Bydureon pen.

Any changes that you just do build are going to be simplest if introduced bit by bit. This may mean that you just are additional seemingly to stay to them, that means you'll introduce additional while not feeling below an excessive amount of pressure. Straightforward changes to form include; swapping staff of life for brown bread, full-fat milk for fat milk, extirpation snacks etc. You must conjointly opt for a weight loss program that encourages gradual weight loss instead of immediate weight loss. By doing this, the load you lose is additional seemingly to remain off and, by setting possible monthly targets instead of fantastic weekly targets, you're additional seemingly to fulfill them.

When selecting a weight loss program it's vital that you just opt for one that's right for you. The foremost vital issue to think about is your health, thus don't be selecting an inspiration that has outrageous claims and will attainable be risky. Set possible goals and build changes that you just are seeming to stay to for the remainder of your life, keeping the load off permanently. The best thanks to changing state isn't to crash diet or have bursts of exercise, however, to form slow changes. The most effective thanks to making these changes and follow them are to form a weight loss program. This will be accustomed to launched your targets, however, you're visiting come through them, and changes as they occur.

In order to change state, you would like to asses your energy intake. Food is employed as energy for your body, and any energy not used is kept as fat. It's thus essential that you just solely soak up the energy you would like and increase your activity level so as to change state. Once reducing your calorie intake, it's essential that you just build changes that you are seemingly to stay to as crash diets might cause 'yo-yo' fasting. Uptake around 300-500 calories less per week can cause a weight loss of 1-2lbs every week, whereas it's not abundant weekly it adds up to around 52lbs annually. it's conjointly vital to not skip meals as this would possibly cause you to overcompensate later within the day and snack additional. Increasing activity levels will be done simply, for instance, attempting to try to twenty minutes of walking every day, like walking short journeys than mistreatment the automobile. By finding one thing that you just get pleasure from you're additional seemingly to stay to that.

By employing a weight loss program you'll implement these changes and follow them. It should conjointly work best if you write you're set up down, keeping a note of your targets, changes in weight and achievements to assist you to retain on course. while you'll not see any immediate changes, persist with it. Don't let any weight gain place you off, and instead, take a look at your program and see if something must modification, like increasing your activity levels. And once you reach your goals celebrate by treating yourself to one thing like an evening out or a replacement outfit to form your weight loss even sweeter.

Another facet of your weight loss program can be a food diary. By writing down all the food and drink you're taking in throughout the week you may notice it easier to determine wherever you're going wrong. You'll review the diary at the top of every week to urge a clearer image of simply what quantity calories you actually are intense. If your diet appearance healthy and however you continue to aren't losing any weight, you'll have to take a look at your portion sizes to form positive you're merely not uptake an excessive amount of.

When selecting a weight loss program https://bydureonguide.com/does-bydureon-cause-weight-loss/ it's vital that you just opt for one that's right for you. The foremost vital issue to think about is your health, thus don't be selecting an inspiration that has outrageous claims and will attainable be risky. Set possible goals and build changes that you just are seeming to stay to for the remainder of your life, keeping the load off permanently.

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Treatment Options for Type 2 Diabetes

Diabetes and prediabetes are two of the country's most serious health problems. Over 1.33 billion people in India are diagnosed and suffering with diabetes.

When blood sugar levels are higher than usual but not yet high enough to be diagnosed as type 2 diabetes, it is called prediabetes. Weight loss and greater activity can help you avoid being diagnosed with type 2 diabetes.

The number of Americans at risk for these disorders is even more alarming: the American Diabetes Association revealed that out of 34.2 million individuals with diabetes, 26.8 million were diagnosed and 7.3 million remained undiagnosed. The best Diabetic specialist kolkata will provide you with the best recommendations for type-2 diabetes treatment. 

Type 2 Diabetic Treatment

Type 2 diabetes has no cure, but patients may control their symptoms by eating well, staying active through regular exercise, and maintaining a healthy weight. But there are instances when this isn't enough.  Changing your lifestyle is one of the best ways to control your diabetes and not let it get out of control. 

Oral metformin, a medicine that forms the backbone of oral diabetes treatment regimens, is frequently the first drug used to treat type 2 diabetes. Different medication types may be added to metformin after that, and injectable insulin may be required for certain people.

Insulin is a hormone that allows the body to use glucose (sugar) from food to create energy.

The pancreas does not produce insulin in type 1 diabetes, thus it must be supplemented. In type 2 diabetes, the pancreas either does not produce enough insulin, or the effects of insulin are resistant, or both. The best Diabetic specialist  kolkata will provide you with the best recommendations for type-2 diabetes treatment depending on several factors. 

Medication For Diabetes Treatment

Sulfonylurea

Glipizide, glyburide, and glimepiride are examples of medications in this class. These drugs are affordable, but they can induce low blood sugar and weight gain.

Insulin Sensitizer

Pioglitazone is a medicine that is effective and does not cause hypoglycemia (low blood sugar). It can, however, result in weight gain. The best Diabetic specialist kolkata will provide you with the best recommendations for type-2 diabetes treatment. 

Agonists for the glucagon-like peptide-1 (GLP-1) receptor

Exenatide (Byetta, Bydureon), liraglutide (Victoza, Saxenda), and dulaglutide (Victoza, Saxenda) are examples of this drug (Trulicity). Some of these drugs are injected daily, while others are injected once a week.

Semaglutide is also available in an oral version (Rybelsus) that may be taken once a day. This sort of medicine is effective and may aid with weight loss as well as heart health. However, it is possible that it will induce adverse effects such as nausea and diarrhea.

Inhibitors of dipeptidyl peptidase-4 (DPP-4 inhibitors)

This category includes a number of drugs. Sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), and vildagliptin (Vildagliptin) are all brand-name medications (Galvus).

Factors Considered By Diabetic Specialists before Recommending Treatment

Your doctor will evaluate the following considerations when deciding which treatment plan is best for you:

Heart disease, such as a history of heart attacks, strokes, or congestive heart failure, is present or absent.

Chronic kidney disease (CKD) is present or absent (CKD)

Potential side effects of diabetes treatment

Cost of medication and treatment

Individual preferences for a treatment plan

Wrapping Up!

Type 2 diabetes is a chronic and complicated disease. Managing it successfully entails employing a variety of risk-reduction methods while also attaining your blood sugar control goals. The best Diabetic specialist kolkata will provide you with the best recommendations for type-2 diabetes treatment depending on several factors. 

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Can you really lose weight with Bydureon? Find out here:

https://bydureonguide.com/does-bydureon-cause-weight-loss

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Bydureon for weight loss: https://bydureonguide.com/does-bydureon-cause-weight-loss/

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AstraZeneca improves diabetes pen to maintain its market share

The European Commission (EC) has approved AstraZeneca’s Bydureon BCise, a new weekly formulation of established GLP-1 diabetes drug with added benefit of glucose reduction, better weight loss results and a new injection pen.  

AstraZeneca announced that the EC green-lighted the new formulation of the once-weekly type-2 diabetes injection, which will be marketed as Bydureon BCise (exenatide 2mg prolonged-release suspension).

The new authorisation has been granted for a single-dose, pre-filled pen device that requires no titration and is approved for use in combination with other glucose-lowering medicines, including basal insulin, to help improve glycaemic control together with diet and exercise.

The EC made its decision based on data from DURATION-NEO-1 clinical trial comparing Bydureon BCise and AZ'[s twice-daily exenatide formulation, Byetta. After 28 weeks of treatment, patients administered with the new formulation demonstrated an HbA1c reduction of 1.4% and 1% respectively.

Additionally, Bydureon BCise demonstrated a mean weight reduction of 1.5 Kg as monotherapy comparing to 1.9 Kg with certain oral antidiabetic medicines.

Elisabeth Björk

Elisabeth Björk, vice president, head of cardiovascular, renal and metabolism, global medicines development at AstraZeneca, said: “Building on the already well-established efficacy and safety profile of once-weekly Bydureon, today’s approval of Bydureon BCise will enable us to offer an additional treatment option for patients with type-2 diabetes whose blood sugar levels are inadequately controlled by other glucose-lowering medicines together with diet and exercise.”

This new formulation of once-weekly Bydureon BCise has been already approved in the US by the Food and Drug Administration (FDA) in October 2017 and hit the market in the first quarter of this year.

Despite improvements Bydureon’s will still face stiff competition to sustain its established drug share on the GLP-1 market.

Novo Nordisk recently published the first promising PIONEER 5 trial results for oral semaglutide, and also claim that its current Ozempic shows the greater levels of blood sugar and weight reduction when compared with Bydureon and Eli Lilly’s Trulicity.

Market analysts suggest that Novo Nordisk will be able to add another blockbuster to its portfolio and further billions to its revenue should semaglutide get approved in a daily pill form.

Also small Israeli biotech Oramed is developing an oral version of exenatide – the active ingredient in AstraZeneca’s Byetta, but this drug is still in mid-stage trials.

The post AstraZeneca improves diabetes pen to maintain its market share appeared first on Pharmaphorum.

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