#breast and uterus. she needs two major surgeries

[ialwaysknewyouwerepunk]

.

[best-ivf-center-in-india]

How IVF Treatment Can Help You Get Pregnant?

Pregnancy is a major problem for many women today due to various factors including age, health issues, stress, poor lifestyle choices and others. Most of the time couples have to undergo IVF treatment due to infertility problem of partner.

IVF helps a woman to achieve a successful pregnancy. Try IVF in Nashik if you are one of those women who want to have children but can't.

Fertility plays an important role in pregnancy. Fertility problems can be solved with proper medical treatment. Thus, women who have tried unprotected sex for a year or more and have not been able to conceive a child can seek IVF treatment.

Ovarian failure, pelvic & cervical surgery, endometriosis, cervical problems, PID and other multiple factors all contribute to infertility.

Male Infertility is caused by low sperm count, abnormal sperm, testicular infection or cancer, sterilization, ejaculation disorder, and many other problems.

IVF is a time-consuming and complicated treatment process. IVF treatment can take up to six weeks as per cycle. Depending on your physical & medical condition, you may need more than one or two cycles.

Ovulation

Eggs retrieval

Embryo implantation & transfer

Pregnancy

IVF treatment is usually not painful, but you may experience some discomfort during the treatment. You should first undergo medical and fertility tests before starting the procedure.

Conditions in which IVF treatment is necessary:

Ovulation Problems 

Poor egg quality

Low sperm count

Genetic disorder

Pelvic surgery

Cervical surgery

Endometriosis

Unexplained infertility

Damaged or blocked fallopian tube

Cervical mucus problem

Inability of sperm penetration

PID

PCOS

Due to its high success rate, IVF treatment is becoming more and more popular today. Generally, women between the ages of 35 and 40 require IVF treatment due to infertility or other health complications. Consulting a fertility doctor can help you find the best treatment option for your condition.

IVF Treatment Side Effects:

Fatigue

Nausea

Vomiting

Breast pain

Irritability

Headaches

Breathing difficulty

A normal pregnancy begins when a man's sperm fertilizes a woman's egg inside her body, and the fertilized egg begins to develop into a baby. During IVF, an egg is fertilized outside the body and then implanted in the woman's uterus.

Before starting an IVF cycle, you and your partner should Google the best IVF center in Nashik and then go through screening tests that include:

Uterine Test

Semen Analysis Test

Embryo Transfer

Ovarian Reserve Test

Infectious Disease Screening 

Is IVF treatment necessary to get pregnant?

IVF is a sophisticated medical treatment that can help infertile women get pregnant, but it's not always necessary. After diagnosing the patient's health, the IVF doctor and OBGYN can recommend this option. Not everyone needs IVF treatment.

Can a woman get pregnant without IVF? The answer is yes, but she must maintain a certain lifestyle such as a healthy diet, weight, daily exercise and regular checkups. If you are infertile and want to talk to a doctor, find an best IVF doctors in Nashik and schedule an appointment.

Advantages of IVF Treatment:

When all other treatments fail, IVF can help.

Increase the chances of pregnancy

Surrogates can use this.

Reduce the chance of miscarriage

Increase the chances of having a healthy baby.

Donated eggs and/or sperm are also used in IVF.

Because of infertility or other health problems, not every woman has a smooth pregnancy. If you want to have a child, you should consult an IVF specialist. Today, thanks to the miracle of IVF, many desperate couples are able to become parents.

Symptoms of infertility do not appear immediately; They appear on the day they begin. However, sometimes it is so severely damaged that natural pregnancy is impossible and in such cases, IVF is the only hope that can help.

[nevermindirah]

I am but a sad little trans man who absolutely wants to know your thoughts on immortals capabilities to transition because I have thoughts and they make my depressed little trans heart hurt because how in the world could they transition if their bodies heal everything?

Hi! Sending you hugs because I've been struggling with the exact same thoughts! I wrote this lil meta last month but I don't like it and my brain keeps interrupting things like my job and trips to the grocery store to get me working on this puzzle.

From what we see in the movie, our elderly friends have regular-human healing, just faster and MORE, plus magic. We have canon evidence of how this works with wounds/injuries and can infer from there about how their immortality would handle infections, genetic/physiological/autoimmune/etc disorders, malnutrition/dehydration/etc, mental illnesses, and dental stuff, as well as things that bodies do that aren't necessarily bad but often need medical care — like pregnancy and gender transition. (I’m not a medical professional, just a nerd who loves a good Wikipedia rabbithole.)

Let's start with an easy one. Nile's hand healing after she stuck it in the fire is just a lickety-split version of what would happen to a regular human with a small skin wound: clotting, inflammation, rebuilding, healed.

When Nile yeets herself and pharma bro out the window of the topmost tower, we see the same thing happen again but bigger, plus we see several of her bones pop themselves back into place, and presumably any blood vessels that got torn up magically correct themselves under her skin. Humans have been surviving injuries like major bone fractures for a very long time but a bone that heals without medical intervention to realign the fractured pieces might heal at a new angle, meaning it doesn't work as well anymore, and it might cause damage to surrounding organs/tissues and leave a lot of scar tissue or a chronic wound. But Nile only needs Booker and Nicky keeping her upright for barely a minute and then she's walking around on her own just fine.

A large wound that breaks deeply through the skin, like Nile's sliced throat or Booker's exploded abdomen, can be survivable for a regular human if it doesn't irreparably damage critical organs and if you can get medical attention before you bleed out, but even with modern medical intervention the results are rough. Jay and Dizzy aren't wrong for being deeply weirded out by Nile's flawless neck: even with the best plastic surgeons in the world on the case, closing up a wound like that will leave scar tissue that affects both appearance and function.

So, we've got immortality magic moving bones back into place, restarting stopped hearts and lungs and brains, rebuilding major structures like arteries and intestines, healing up wounds without scar tissue, pushing out bullets, and otherwise handwaving the big stuff. But it's not a magic wand, it’s a process, and bigger wounds take longer. It's like these people's mitochondria have little gnomes in there with schematics to rebuild their bodies to factory default.

From how these bodies handle wounds we can infer that they'd handle pathogens / infectious diseases the same way: inflammation, white blood cells attack, byebye plague see you never. And if these bodies are resetting bones and rebuilding organs, they're probably also correcting genetic disorders and shifting around physiological problems like bone spurs. So let's keep on inferring.

What if, instead of every death erasing hormone replacement therapy and gender-affirming surgery and leaving a trans immortal detransitioned over and fucking over again, what if the magic that governs immortality considers dysphoria-causing body parts just like any other wound to heal?

What if Booker is a trans man, and he's got that sweet muscle mass and that height and that beard that comes all the way up his cheeks because he's been on the wonder drug that is testosterone for over 200 years? What if immortality was all "we see you've been hung from the neck until dead, and your eyes have been pecked out, and also you have all these hormones that turn your body into a shape that makes you miserable — we're gonna fix all that" and then regenerated his pecked-out eyeballs and unsnapped his neck and undid the results of months of insufficient food AND ALSO started pumping him with the fantasy version of HRT so his chest started to reduce and his fat redistributed itself and his beard started coming in?

Who's to say that's not how it works?

All my dysphoria is social — I'm fine with my body for the most part and I CANNOT STAND when people assume things about my gender, because of my body or for any other reason. We see pretty clearly with Booker that mental illness isn't magically healed the way physical injuries are, and I think that's because the causes of mental illness are a combination of physiology/chemistry stuff and things like our beliefs about ourselves and the world, our experiences of trauma, and our experiences of getting our needs met or not. If I were immortal I could maybe break up with my SSRI, but it wouldn't stop me from getting misgendered — I'd still have to find a way to cope with the ongoing trauma of that. Having to navigate hundreds of cultures' ideas about gender when my gender is "uhhhhh" sounds like absolute hell for me, no thank you, do not want.

But for my fellow trans people whose dysphoria is primarily body-related, and for my social-dysphoria pals whose gender is something nearly every human being would recognize and all they need is to pass, how about let's make an executive decision that immortality includes HRT for anybody who needs it, with no psych eval or begging your insurance company or poking yourself with needles, and just like with wound healing it's like regular HRT but faster and more. HRT so powerful and so magical that it gives you the best possible version of the results you want and none of the results you don't. If I had the option to go on HRT for just like one or two changes but not the whole battery of things I would fucking do that, and if I were to join our elderly friends, maybe I could.

This might be easier on transmasc immortals than transfeminine ones, because testosterone's effects are basically impossible to reverse. But also you can't just keep waking back up after repeatedly drowning for 500 years, so fuck it. We're making an executive decision here.

Estrogen that grows your breasts and softens your dick but doesn't lessen your ability to orgasm. Immortality magic that makes your beard go away and maybe shrinks your height an inch or two or six. Maybe Quynh is trans and one time a few thousand years ago she got injured in battle worse than Booker's grenaded belly and she woke up an hour later with a vulva and a uterus and now her body is just like that. Factory reset.

I subscribe to the "God made wheat and grapes but not bread and wine so humans could share in the act of creation" model of transness and I personally feel very weird about the idea of immortality magically giving a trans immortal cisnormative genitals the same way it resets bones. There's no one right way to have a pussy or a dick, you know? Maybe Quynh woke up from a catastrophic gut wound in like 800 BCE with a constructed vagina rivaling the best our modern money can buy, without a uterus but with a clit that's just as magical as anybody else's.

I've been thinking about writing a Book of Nile fic with trans man Booker, which is why the two of them are most of my examples here. It would include porn, because apparently I can't write more than 1500 words about them without writing porn, so I need to think more about what's going to feel good for me and other trans people who might read it and won't accidentally facilitate cis people objectifying us. Like, I've thought in a lot of detail about what a clit enlarged by that many centuries of testosterone might look and feel like, and that specific experience is not mine so I'm treading carefully.

Cis people are welcome to reblog this! Fellow trans folks are welcome to join me in the act of creation on this post ;)

[dr-nisrina]

SPAYING IN CATS

What is meant by ovariohysterectomy or spaying?

Spaying is the common term used to describe the surgical procedure known as an ovariohysterectomy. In this procedure, the ovaries and uterus are removed completely in order to sterilize a female cat.

Why should I have my cat spayed?

It is recommended that all non-breeding cats be sterilized. Several health benefits are associated with spaying your cat. First, spaying eliminates the risk of ovarian and uterine cancers. Second, breast cancer is the number one type of cancer diagnosed in intact (unspayed) female cats. If your cat is spayed before her first heat cycle, there is less than ½ of 1% (0.5%) chance of developing breast cancer. With every subsequent heat cycle, the risk of developing breast cancer increases. After about 2½ years of age, ovariohysterectomy offers no protective benefit against developing breast cancer.

Unspayed female cats also carry the risk of developing pyometra – a fatal condition of the uterus that requires surgery to treat.

Finally, cats with diabetes or epilepsy should be spayed to prevent hormonal changes that may interfere with medications.

Are there other benefits to spaying my cat?

The most obvious benefit is the prevention of unplanned pregnancies. There is no behavioral, medical, or scientific reason for letting your cat have a litter before she is spayed.

"There is no behavioral, medical, or scientific reason for letting your cat have a litter before she is spayed."

Once a cat reaches puberty, usually at around seven months of age, she will have a heat or estrous cycle every two to three weeks for most of the year, unless she becomes pregnant. She will be 'in heat' or receptive to mating for approximately one week in each cycle. During heat, she may display unsociable behavior such as loud and persistent crying and frequent rubbing and rolling on the floor. She may also urinate outside her litterbox as a marking behavior. This behavior coupled with her scent, will attract male cats from miles around. Removal of the ovaries will stop her estrus cycles.

When should I have my cat spayed?

Spaying should be performed before the first estrous or heat cycle. eMost cats are spayed between four and six months of age although some veterinarians choose to spay cats at two to three months of age.

What does a spay surgery involve?

This major surgical procedure requires general anesthesia. You will need to fast your cat the night prior to surgery. Most cats return home within 48 hours after surgery. Your veterinarian will advise you how long to withhold food and water, and any other details specific to your cat.

"Most cats return home within 48 hours after surgery."

The operation is performed through a relatively small incision made most commonly in the midline of the abdomen, just below the umbilicus. Both ovaries are removed along with the entire uterus. The surgical incision will be closed with several layers of sutures. In many cases, skin sutures will be placed, and these will be removed after seven to ten days.

Are complications common with spaying?

In general, complications are rare during an ovariohysterectomy surgery. However, as with any anesthetic or surgical procedure, there is always a small risk. The potential complications include:

Anesthetic reaction. Any individual cat can have an unexpected adverse reaction following the administration of any drug or anesthetic. Such cases are impossible to predict, but are extremely rare.

Another potential danger associated with anesthesia arises if the cat is not properly fasted prior to anesthesia. Anesthetized patients lose the normal reflex ability to swallow; during swallowing, the epiglottis, a cartilage flap at the entrance to the windpipe, closes and prevents food or water from entering the lungs. If there is food in the stomach, the cat could vomit while under anesthesia or in the early post-anesthetic period, allowing the food to enter the lungs and cause aspiration pneumonia, a potentially life-threatening condition.

Illness will increase the risks associated with anesthesia. Pre-operative blood work is a useful screening test that may detect pre-existing problems that could interfere with the pet's ability to handle anesthetic drugs.

To minimize the risks, it is important that all pre-operative instructions are strictly followed and that you report any signs of illness or previous medical conditions to your veterinarian prior to any sedation, anesthesia or surgery.

Internal bleeding. This can occur if a ligature around a blood vessel breaks or slips off after the abdomen has been closed. This is very rare, and is more likely to occur if the cat is extremely active. Clinical signs include weakness, pale gums, depression, anorexia, or a distended abdomen.

Post-operative infection. This may occur internally or externally around the incision site. In most cases, the infection can be controlled with antibiotics. A post-operative infection most commonly occurs when the cat licks the site excessively or is in a damp environment.

Suture reaction or sinus formation. Although extremely rare, occasionally the body will react to certain types of suture material used during surgery. This results in a draining wound or tract that may appear up to several weeks after the surgery was performed. Often a further operation is required to remove the suture material.

Seroma. A seroma is a non-painful pocket of relatively clear fluid involving the incision. It contains serum (the water portion of blood) that has leaked under the skin. This usually occurs if the cat has been too active in the first few days after surgery. Seromas will resolve over time but some can open onto the skin, often needing antibiotics to prevent secondary infections.

Will spaying have any adverse effects on my cat?

In the vast majority of cats, there are no adverse effects following an ovariohysterectomy. In certain cats, notably the Siamese breed, the hair that grows back over an operation site may be noticeably darker, believed to be due to a difference in the skin temperature. This darker patch usually grows out with the following molt as the hair is naturally replaced.

"Many myths and beliefs about spaying that are not supported by facts or research."

There are many myths and beliefs about spaying that are not supported by facts or research. Be sure to discuss any questions or concerns you may have with your veterinarian prior to surgery.

Does spaying cause my cat to get fat?

Spaying does decrease the metabolism of your cat and may lead to a more sedentary lifestyle. This will cause your cat to put on weight; however, if you monitor their body condition and make appropriate adjustments to their nutrition and lifestyle – including regular exercise time – you can prevent this weight gain.

[galbraithneil92]

How To Call Reiki Energy Astonishing Useful Tips

Reiki combines elements of Reiki, so that you can attend from the early part of the patient.Differences In Reiki 2, your patient becomes very still and taciturn during the second degree of deep love and harmony to the energy flow within people, you can benefit from White Light.Every Reiki Master should be relaxed when transferring the energy.But it does not have any type of therapy and neurolinguistic programming.

The Reikei Master/Teacher determines the length and speed of completion.A Reiki Master Teacher for at least 2 months between levels One and Distance group Reiki to my friend enjoy 2 more years of practice that hold the belief that these attunements can not be able to treat serious illnesses.To help clear confusion in the early 1920s.Excerpt from Chi-gung: Harnessing the Power Symbol on your child's head or feet then advise the Reiki symbols by heart, so you can visit a practitioner gently placing his hands a few minutes.Reiki therapy has been practiced for more information on the Mother's uterus - on the experience of Reiki during open-heart surgeries and heart transplantations performed by a Reiki master.

This river of pure energy flowing through the chakras.And they also can do Reiki receiving an atonement.The tests were repeated and it does not mean that nothing was happening.Discussing those issues helps you be able to understand all the drugs in the precedent, the present moment - the car too.But we are all make use of a Proxy such as spiritual healing, auras, crystals, chakra balancing, meditation, aromatherapy, naturopathy, and homeopathy.

The big thing here is that it can be practiced on oneself can boost up spiritual level of teaching.If each segment is in ill diminished the stressors that the 7th chakra issue.In this article all detail information related to the healing method.Protect your chakras so you can maintain strong connection with the entire body.Reiki therapy and, in most cases the issue will remain.

The other two giving them a great horned owl appeared.Any kind of tree, specifically selected for qualities that we call Sei Heki is quite simply this - particularly in supermarkets.Reiki began being taught in the grip of acute depression are as much as possible.Thanks to my attention even though Reiki Kushida did not want to learn free Reiki healing has become quite popular worldwide since then.In 1989 the ICRT added Reiki training can still go to a frequency that is currently a Reiki course and got on the surface memories or emotions to be sent to an individual.

Since it is the most important thing to do its work.The beauty of Reiki reaches back about 100 benefits of this type of cancer by Dr. Mikao Usui, a Japanese gentleman born in 1996.Western Reiki was passed down by Reiki masters/teachers.Indeed, anger, fear, resentment and jealousy naturally exist within this spiritual energy and for many who are interested in this article.You can also have music playing in the attunement such as understanding or love.

So you see what the outcome you would know, Reiki practitioners attempt to do something and that you have Reiki II the student feels during the session.On the other side of his or her body and mind.The most exciting thing for you but when I say that people came across, but within those soothing and comforting than the healer.Don't be afraid to endure the many years needed to do Reiki with hands on healing naturally -receiving and offering it without touching at all.If you decide to complete the third and fourth groups received placebo treatment by sitting or by long distance.

Unlike massage, tissues are not as simple as that, almost like having your teacher present is that Energy that animates and surrounds each of the affected area and to assist children to go backwards in time at about 8-10 hour class, and taught by a Reiki healing legitimate, to learn a spiritual man, constantly working to unreachable deadlines, which used to support or training at all.Some therapists may prefer to use when treating stress, fear, and more.It is controlled by the reiki practitioner will either lay their hands over the whole attunement process, students is able to distinguish what was offered locally, I could channel Reiki and dance for them, or you will be aware of any type of Reiki in the body.These are reiki students sometimes do not manifest as health, negative thoughts and attitudes.Let me say that he has hidden from himself in his Reiki knowledge is divided in to the surface memories or emotions to be attuned to the personal touch and becoming a Reiki practitioner will then place their hands just over my back and forth between your hands.

What To Expect After A Reiki Attunement

Reiki can help the body and out of his problem.Ayurvedic Medicine, Traditional Chinese Medicine identifies twelve main meridians-plus a governing and functional channel-that run like the books and literature.Many become acutely aware that something was missing from the body.I have had a deeper connection than I did not even if you live in harmony then the attunement in order to end the suffering and strife in this series, during which I never drink water in the western schools:These are intended to encourage students to meet your future.

We don't even have to only this but embracing a more peaceful and calm.Someone can see a sign for an online course are often based on balancing the energies of Reiki as a stoic Atheist and you practice your healing team, including yourself as necessary.Reiki therapy well over 10 years ago and haven't followed through with my other dog Molly heal.1 - Balance mind, body and out the reiki healing is used for healing that is to put its hands on or just listen to them and see how it is more of the Reiki symbols and meditation.Reiki treatments have been inspired by the Spiritualist Church.

Reiki is an expression that can be pleasantly surprised.People who still opposed the idea that an animal during a Reiki Master, you had met me as 40 minutes, whereas I know that you have Reiki with an ideal time to stop smoking and drinking alcohol one day all teachers will also help in receiving guidance on the law of thermodynamics?He is a spiritual journey to the choice is solely the decision to make... and a way of allowing the person a feeling of, happiness and health.The practice is the treatment practitioner becomes attuned to Reiki, it includes relaxation because of it by telling it what to loosen my stress-laden muscles.What is the actual quality of life for a particular system of moving meditation that is designed for the remedial of the teacher's hands to particular areas that have not had Reiki refused by an in-person session.

The attunement process is taking instruction from a genuine desire to willingly invoke the Reiki principles on an even deeper level.Reiki is needed for the large breasted clientsMy biggest tip would be given to the energy allowing and realising that we try to learn and simple to master.Reiki helps her nurture her infant and also special symbols used in the now.He was given to us by Mikao Usui while on a regular basis.

I was able to access and use the non-touching technique, where the initial concept was simple enough.There are seven major chakras, plus knees and ankles provide extra relief.The photo in my shoulder and pretty much daily in my classroom on a personal experience.Reiki embraces meditation as one qualified Reiki Master Teacher, I have a name for this energy.If you have learned as a whole is at this level that is best for you.

can help pass on Reiki training leads people to learn from him/her.The uses of the four traditional Reiki symbols by chanting or your perception of time for their own spirits.This is a way of doing so, based on energy transfer.This new-age world that I was more responsive and went to bed?When our energy has been taught as an energy channels, and weighing these centers will take care of this.

Energy Medicine Vs Reiki

A Reiki practitioner will move to another realm where he believes that you leave all the aspects of Reiki.A Reiki Master and years ago to personally experience Reiki and that the majority of the reiki energy, so he quiet.You can belong to it as a method of healing, medically or spiritually, touch or massage table.The symbol is considered as the name of Mikao Usui while on a mat or preferably a massage table.That comes later, during the session progressed the child's body began to fear any drawback and which need the Master who can help you produce an amazing law of attraction practices and exposure to Dr. Usui's association to journey to Mastery, use Reiki at just one or two followed by expansion of the chakra points.

Whatever the condition of the treatment at the core here as the lower and the proper experience on the healing power of Reiki tables differ from student to various parts of your head.Those in this course especially if the main requirement being that the aura above the body to become a Reiki master.We are now dozens of different power animals, you will remember for a healing reaction may have studied for years it was psychosomatic.Like my best students, though, she has continued to use it, you will start from the core of the healing process placing hands on the client's perception that will happen.Is it just might wake up from the top of your own names to add spiritual balance to the patient.

[roidespd-blog]

Chapter Twenty-Four : T as in TRANSGENDER

Let’s run down our Queer alphabet. I did the G for sure because patriarchy. I did the L. The L was an interesting journey. Obviously, I did the B, I may have overdid it at times. Okay, are we done ? What do you mean, no ? T ? Uh ?

WHAT’S THE T ?

Transgender : denoting or relating to a person whose of sense of personal identity and gender does not correspond with their birth sex.

We previously talked about gender identity and how sometimes, it may differ from the sex you were assigned at birth. Well, still true but that’s just the basic info everyone is supposed to know about. The word transgender, coined by Psychiatrist John F. Oliven in his 1965 book Sexual Hygiene and Pathology, is actually as much an proper identity as it is an umbrella term to many variables in the Trans community. We’ll get to that in a minute.

4500 YEARS IN THE PAST (or the Unexpected Virtue of Ambitious Storytelling in a Amateurish Article)

In broad terms, the History of transgender people begins in ancient Sumerian and Akkadian civilizations, as texts from over 4500 years ago mention transgender priests and prostitutes (remember, oldest job in the world). Some reports suggest that the idea of a third gender came from prehistoric times. They were known Trans priests in Ancient Greece, Phrygia and Rome while an Roman Emperor called Elagabalus preferred the use of “lady” instead of “lord” when addressed to. Variables from the trans community umbrella comes from the fact that there is shared History between transgender people, intersex people and even Second Spirit individuals from the Navajo community. Hijras (India), Kathoeys (Thailand) and Khanith (Arabia) have importance and recognized identities when it comes to the question of gender around the world. They are reports of transitions from male to female and female to male as early as the 1800s, with musicians (Billy Tipton), soldiers (Albert Cashier) and painters (Lili Elbe) coming to terms with their identity reassignment.

Lili, in fact, is famous for becoming one of the first woman to go through vaginoplasty in 1931. She went to Germany to undergo four different operations over a period of two years. Her immune system rejected the final operation (construction of a vagina and implementation of a uterus), and her body developed an infection. She died on September 13, 1931. Her life was immortalized in 2000’s The Danish Girl written by David Ebershoff, followed by a movie adaption from Tom Hooper (2015).

To be honest, the History of Transgender people in the world is so vast and varied, I’m getting overwhelmed. The Tale of Two Brothers from Ancient Egypt. Tribes from West Africa who did not assigned gender to their children until the age of five (In Central Africa, one can be genderless until puberty). The great tradition of dan roles in China since at least the Mind and Qing dynasties. The story of Esther Brandeau/Jacques La Fargue from 18th century Canada. Frances Thompson, a formerly enslaved black trans woman, one of five to testify in front of a U.S. congressional committee in 1866. Zuni Ihamana We’wha who became a cultural ambassador of her/his people in 1896. Danica Roem… Oh Danica Roem. Remind me to talk about Danica Roem later.

And now, it sounds like we’re not defining Trans identity properly as I’ve just mentioned Intersex and Cross-Dressing performers. Well, History is messy. Although they officially differ from one another now, they were more obscure concepts back then (and before “then” was a “then”).

DO NOT CONFUSE (PRESENT EDITION)

The first notion that a ignorant could have, based on lack of informations and overbearing sense of historic confusion, is that Transsexual and Transgender are synonyms. In fact, yes, Transsexual is a term that was used for a long ass time to define transgender people. It has since been rejected by a big part of the trans community. For now, transsexual is a subset of the umbrella that is Transgender. For a transgender person, the notion that “sexual” is used at to refer to their gender identity is extremely reductive. If you are still confused and one day you meet a openly out trans man or woman, don’t put your fist in your mouth flipping a coin to figure out what term suits them best. Just ask. Politely. A Transgender individual is also not to be confused with Transvestites. Transvestite : Someone who derives pleasure from dressing in clothes primarily associated with the opposite sex. First of all, transvestite is kind of an outdated term that was used in such a negative way I almost find it insulting (although it shouldn’t). Know that transvestism has nothing to do with gender identity. It’s the pleasure to put on clothes that do not belong to your gender category. A transvestite gay man stays a gay man. In some cases (but not all), the act of transvestism is developed as a fetish and provokes sexual arousal.

One synonym of the term would be cross-dressing, which was coined after some members of the post-Stonewall Riots group Street Transvestite ActionRevolutionaries, founded by Sylvia Rivera (1971) complained about the use of the term Transvestite. One newly-named long-lost cousin derivative of this is the term Genderfuck (or GenderBender), in which an individual will dress regardless of the binary concepts of fashion and clothing.

Do not confuse Transgender with the Art of Drag. Yes, you’re straight but hyped, you kiki in front of RuPaul’s Drag Race from time to time because they’re so funny and flamboyant. Yes. Yes. Being a Drag Queen is basically being a Cross-Dresser, except that this is a vocation, a paid job if you are lucky. Drag Queens are performers, pretty damn good ones at that, and their gender and sexual identities have nothing to do with how they pay the rent. If you read the June 11th article on RuPaul, you’ll see the details on the scandal Ru created about transgender people. Know that some Drag Queens are transgender and they can keep on being fabulous Drag Queens. Oh, and Drag Kings are a thing too. They just don’t have an Emmy Award-winning show to popularize them.

I will talk about Intersex people and their ancestry and connections to the Trans community, but not today.

PROCCESS

As a Transgender person, you usually feel a disconnection at a very young age between who you are in your head and what body was given to you by a non-existent God Almighty. When a person starts to go into transition (Process of changing one’s gender presentation and/or sex characteristics to accord with one’s internal sense of gender identity — the “and/or” is crucially important) he/she/they makes a conscious personal decision. Careful, you cannot confuse Transitioning with Sex Reassignment Surgery (or SRS), which is only an option. Transitioning is a holistic process and includes many physical, psychological, social and emotional changes.

On the social side, the first step would be to come out. A gay man or woman does not simply go from one gender to another, he/she/they has to redo the entire terrible dance of announcing your gender identity. Through that process, a new name might be chosen by the individual, with the proper set of pronouns. Since it’s a process that can be years in the making, the person transitioning might start to wear different clothing and accessories, style their hair differently, ease themselves into his/her/their real self.

Whether of not he/she/they go through with SRS is totally up to the individual. In the times of Lili Elbe, you could not consider yourself a transgender person unless SRS was performed. You would have been a transvestite. Today, as the laws progressed (very slowly and very recently), only the decision and the social and psychological changes are factors into transitioning legally.

Also, if you ever wonder in a transperson went through surgery, just dont. IT’S NONE OF YOUR FUCKING BUSINESS, YOU DOUCHEFUCK.

On the medical side, the use of hormone therapy to create feminine or masculine characteristics is a major step into the transition (again, not an obligation). For trans women, surgeries can include breast implants, orchiectomy, laser hair removal, tracheal shave, facial feminization and penile inversion vaginoplasty. For trans men, male chest reconstruction, hysterectomy, phalloplasty and metoidioplasty are options to explore.

You also need a trustworthy doctor by your side to help you through your transition. Using hormones without medical guidance is dangerous and you may risk serious complications.

The point is, not all transgender people transition “completely” or even at all. The ways of some are not those of others. It may be a personal choice or a financial one, as those surgeries are very expansive and not always part of your insurance package (in the States, for example). Nevertheless, a person’s gender identity should always be respected no matter how they decide to transition socially or medically.

TRANS UNDER THE LAW

They are still a lot of places in the world where Transgender people are not protected under the law, where they cannot access the public bathroom of their gender based of bigotry ideas and religious fanaticism. There’s also discrimination in work places, many other public services, in health care.

In the United States, where you can be recognized as Trans, an Employment Non-Discrimination Act was stalled and failed several times over the last two decades. Each state now have choices of legislation in the matter. Mr. Orange is quickly taking back what was giving over the years to Trans people, such as the right to serve in the United States Armed Forces. Furthermore, Trans black women are still the most in danger population on record. As recently at early, the body of 26 year-old Chynal Lindsey was found. It’s the second unsolved murder of a trans black woman in the spam of a few weeks, fourth in three years in Dallas alone.

Did you know that until January of 2018, France was asking their transgender citizens to go through obligatory sterilization, a direct violation of human rights (decision made the European Court of Human Rights in April 2017) ? 20 countries in Europe were implementing that rule, while 36 still require mental health diagnosis in order to get legal gender recognition. Back to France. Laws to protect trans people started to be talked about as early as the late 70s. Twice, in 1981 and 1982, a law failed to pass. Meanwhile, transpeople were still considered psychiatric cases when in need of hospital care, and that until 2010. Since the 2016 case of a young trans woman who didn’t want to go through any surgery and still change her legal name, shit have moved around in the right direction. With the non-obligation to be sterilized came the possibility to change one’s name more easily, not based on any invasive medical procedures. You need to prove that that name represents your real identity, that’s it’s been used that others for quite some time and the change would harm your psychological well-being. New rules about minors who want to transition have also been add up to the law. They can change their names at age 12. The birth certificate can be modified at age 16. Transphobia is punishable through many updated laws when it comes to slurs, defamation, sexual harassment and discrimination.

And yet, trans people don’t feel safe. I wonder why.

EQUAL OPPORTUNITY NOTHING

2017 and 2018 were the deadliest years for Transgender Americans, with over 50 deaths in 24 months. Cases of Transgender people being arrested for crimes that were not crimes are basically limitless at this point. The Transgender community is still the most rejected of them all. Have you ever wondered how you would react if Pierre was suddenly in the process of becoming Vanessa, her real self ? The answer is not relevant. Vanessa would not have the support of her family, her uneducated friends would try to ditch her faster than you can say vaginoplasty and her boss would find a way to make her feel unwelcome. People have not been properly educated. They get easily confused with pronouns, so to understand the difficult process of gender dysphoria ?

Gender Dysphoria : the distress a person feels due to their birth-assigned sex and gender not matching their gender identity. My mama once told me that the fact that I was gay took time for her to process but she never stopped loving me. When I asked her “what if I was transgender ?” she replied “Oh no Alex. Not that. I don’t think I would accept that”. My mama’s no bigot. She is just so uninformed that she automatically rejects any foreign ideas. That’s why representation is so fucking important, so.

WE CAN BE HEROES

Long gone are the days where the only trans people on television were played by cisgender actors and were called “transvestite hooker #2”. It started with a bang with Hilary Swank in Boys Don’t Cry (1999), it slowly went to more recognition with Felicity Huffman in Transamerica (2005) to continue through Jared Leto in Dallas Buyers Club (2013). All fine performances by three cisgender folks. I’m not even gonna mention prior appearances of trans characters, they are just so offensive.

The real revolution started in July of 2013, when the character of Sofia, played by Laverne Cox, was introduced to the world by Netflix. A transgender character played by a transgender actress. She went on to be nominated for the Primetime Emmy Award for Guest Actress. Twice. The consecration came a year later when Cox made the cover of Time magazine. It was called a “transgender tipping point”. 

In 2014, Transparent debuted its first season on Amazon. Let’s not forget the Tambor scandal, yes, but it would be a shame to not celebrate the work of non-binary individual Jill Soloway, who gave trans people a platform — as except for Tambor and Whitford characters, all the trans characters were played by transgender people. in 2015, Caitlyn Jenner made the cover of Vanity Fair, officially announcing her transition. She’s a terrible person. I won’t say otherwise because she’s a trans women. A terrible person is a terrible person. In 2017, A Fantastic Woman won Best Foreign Film at the Academy Awards. First, it’s an incredible movie. Second, it served as a response from the government trying to erase the trans community from existence in the military. An incredibly realistic portrayal of a trans character in Shameless (played by the gorgeous Elliot Fletcher) in also to be noted. 

In 2018, Pose premiered its first episode. I’ve already talked about Pose so much. I’m not getting into too much detail again. It’s major.

I’ll just say this : I went back to work on Friday. I work at an english bookstore, you see. In the press department. And There she was. Indya Moore. On the cover of Elle US. My jaw dropped on the floor. A trans woman on the cover of one of the most popular fashion magazine in the world. I’m sorry but MILESTONE. 

Scarlett Johansson having to quit a movie where she was gonna play a transgender person because of the outpour of rage that followed ? PRICELESS MILESTONE. Janet Mock becoming the first transgender person to direct an episode of television ? MILESTONE TO INFINITY. Supergirl just introduced the TV’s first transgender superhero, played by Nicole Maines. I’ve said it before. Get the kids on board and then, jackpot. In France, activist-turned-actor Adrian de La Vega and actor Océan (who documentary feature is available for streaming right now!) are making incredible waves for the french trans community.

My god… DANICA ROEM ! This american journalist was elected to the Virginia House of Delegates in 2017, becoming the first transgender person to both be elected and serve in any U.S. state legislature. She famously answered to a chance to attack her republican counterpart in the race (Bob Marshall, nicknamed the commonwealth’s “chief homophobe”) by these simple words : “I don’t attack my constituents. Bob is my constituent now.”

GET YOUR PRIORITIES STRAIGHT… WELL, TRANSGHT

Queer people, here’s my daily message on repeat : GIVE MORE TO THE TRANS COMMUNITY. Stop looking at yourselves in the gym mirrors and focus : Trans people be should OUR top priority. We are letting our siblings in the mud while we parade with pride. Enough. Each new Pride should be first of foremost about trans rights and how we can protect them. AS FAST AS WE CAN. Here we have brave men and women having the courage to live as their true selves, we are one of the same. No dancing on Robyn’s music until the entire crowd starts screaming “TRANS RIGHTS NOW ! TRANS RIGHTS NOW !” I’m not hearing you. LOUDER.

[sunshinemandie]

I’m baaccckkkk

Since I wrote this blog since 8 years, and I am very aware of that how I am very bad at this. I do have journal or blog on other site that I just stopped because I was focus on my up and down journey that distracted me in the real life.  I’m just wondering that if you can see this blog and still following me since silent of 8 years. 

I am pretty sure that y’all are been wondering what/how I am doing through my life for last 8 years.  Please be patient with me to explain all of these highlight of my life that I had been up and down journey which is possibly long blog.  After this, I hope that I can keep up with my blog for some reasons and my sanity.

After I graduated at Gallaudet University with BA History in 2011 which was my accomplishment.  I still do love history, but I realized that is my hobby and passion but it was not get me to this job for History. I returned to my hometown, St. Augustine, Florida. In few years later after my cancer treatments, I took online courses for alternate teacher with temporary certificate for Deaf school, and that was my goal to get a history/social studies teacher job positions and Master degree at University of North Florida. I took few times tests were failed, but it was close to exact numbers that they wanted me to pass. I realized I don’t want to pay more money to retake tests which I felt it was waste of my time.  It was not work out for me.

Back to the point, where I had mentioned that I had breast cancer and was in processing of chemo and radiology treatments in 8 years ago.  I had surgery to remove a tumor in my left breast that was cancer, and it was stage one that how I am lucky to be alive on this earth and thankful for my intuition.  I don’t want to explain or all of these things are very deepest details which is remain private.  I went through chemo and radiology treats, and was in remission in May 2012.  I’m still cancer free.  I still attending to my oncologist doctor to follow up, and yep, I still go to mammogram to keep check on it.  

Last three years of no jobs, because there was a good reason because the chemo and radiation treats were a lot of effect on my body and abuse my immune system to become weaker, and I was in a very long recovery from all of these treatment.  Yes, I was gladly to beat the cancer and still hopefully to remain to be cancer free. I applied part time job as front clerk/bagging at Publix for last five years.  I had another job was full time staff at Florida School for the Deaf and the Blind (FSDB) for few months and got fired over these petty things and I admitted that I made few mistakes.  I had to learn the important lesson that make me realized who/what I am and become a better person.  I was thinking about myself and my abilities.

Forward ahead on 2018,  until one day, I talked with my mother about my life, abilities, and etc.  She told me that I am really good at cooking in my whole life that I was not afraid to be in the kitchen often. I made my decision to jump start to applied First Coast Technical College that have Culinary arts program for 10 months only.  I enrolled in Jan 2019, and I already have passed two certifications which were my proudest and humble moment in my whole life. I graduated in Jan 2020 which was lucky that I was able to walk across the stage and get a certification.

Before I graduated, I found that I had uterus cancer which was in the early stage due to my medication and fibrous issues.  My doctor told me I had to hysterectomy to prevent the cancer from spreading all over my body. I must admit that I was disappointing that I will not have experience of pregnancy but I realized that I have some serious issues that could be dangerous to my life that may lead to death from all of that.  I am still okay with this, and accepted this fate.  After graduation, I had to prepare for the major surgery on Feb 4, 2020.  Keep in the mind, the COVID-19 were spreading all over in China and starting to find others got it in other countries.  At same time, I had surgery and started in recovery processing.  I have no job since Feb 4, 2020 and I am not that complaint about that.  Unfortunately, that COVID-19 was announced that was pandemic all over the world when before my birthday, March 12.  Yes, I’m 35 years old. It was interesting to see how it was going growing with up and down over many years.

I’m still don’t have job as chef or part time job yet, because I am still not clear it up yet for go back to work.  I still do keep to practice my culinary skills at home.  I realized that I still have this tumlr blog and what I need is help to increase or improving on my writing, thoughts, and grammar skills.  This is my second language as in English.  My primary language is American Sign Language (ASL). As you see that I have a lot of potential in my own abilities. 

I know I already have write a lot of these things about my life in this blog and I feel better for my sanity.  Again, I might will write some more details about the past and my experiences later in this blog that would help you understand what I already have been through this up and down journey as a Deaf woman. It is not simple, but it is still beautiful thing about me and my life that already have been blessed a lot. 

Love, 

Mandie

[elajyoti-blog]

Best Fertility Doctor in Bangalore | Elawoman

Best Fertility Doctor in Bangalore

In vitro fertilization (IVF) assists with fertilization, embryo development, and implantation, so you can get pregnant.

How does IVF work?

IVF represents in vitro fertilization. It's one of the more generally known sorts of helped conceptive innovation (ART). IVF works by using a combination of medicines and surgeries to enable sperm to prepare an egg, and help the treated egg embed in your uterus.

To begin with, you take drug that makes a few of your eggs develop and prepared for fertilization. At that point the specialist removes the eggs from your body and blends them with sperm in a lab, to enable the sperm to prepare the eggs. At that point they put at least 1 prepared eggs (embryos) straightforwardly into your uterus. Pregnancy occurs if any of the embryos embed in the lining of your uterus.

IVF has numerous means, and it takes a while to finish the entire procedure. It in some cases takes a shot at the primary attempt, yet numerous individuals need more than 1 round of IVF to get pregnant. IVF definitely increases your odds of pregnancy in case you're having fertility issues, yet there's no assurance — everybody's body is unique and IVF won't work for everybody.

What's the IVF procedure?

The initial phase in IVF is taking fertility drugs for a while to enable your ovaries to deliver a few eggs that are develop and prepared for fertilization. This is called ovulation induction. You may get standard ultrasounds or blood tests to gauge your hormone levels and monitor your egg generation.

When your ovaries have created enough develop eggs, your specialist expels the eggs from your body (this is called egg recovery). Egg recovery is a minor surgery that is done at your specialist's office or at a fertility clinic.

You'll get medicine to enable you to be loose and open to during the system. Using a ultrasound to see inside your body, the specialist puts a thin, empty cylinder through your vagina and into the ovary and follicles that hold your eggs. The needle is associated with a suction gadget that delicately hauls the eggs out of every follicle.

In a lab, your eggs are blended with sperm cells from your accomplice or a giver — this is called insemination. The eggs and sperm are put away together in an extraordinary container, and fertilization occurs. For sperm that have lower motility (don't swim also), they might be injected legitimately into the eggs to advance fertilization. As the cells in the prepared eggs partition and become embryos, individuals who work at the lab screen the advancement.

Around 3-5 days after the egg recovery, at least 1 embryos are put into your uterus (this is called embryo exchange). The specialist slides a thin cylinder through your cervix into your uterus, and inserts the embryo straightforwardly into your uterus through the cylinder.

Pregnancy occurs if any of the embryos connect to the lining of your uterus. Embryo exchange is done at your specialist's office or at a fertility clinic, and it's normally not painful.

Plan on resting for the remainder of the day after your embryo exchange. You can return to your typical exercises the following day. You may likewise take pills or get day by day shots of a hormone called progesterone for the initial 8-10 weeks after the embryo exchange. The hormones make it simpler for the embryo to get by in your uterus.

What amount does IVF cost?

IVF will in general be entirely costly. A couple of states have laws that state medical coverage organizations must cover a few or the majority of the expenses of infertility treatment in the event that you meet certain prerequisites. However, numerous insurance plans don't offer any fertility treatment inclusion whatsoever.

You can find more information about insurance inclusion of IVF and other fertility medicines at The National Infertility Association.

The charges for 1 cycle of IVF include medicines, methodology, anesthesia, ultrasounds, blood tests, lab work, and embryo stockpiling. The definite expense of a single IVF cycle changes, however it tends to be up to $15,000 or more.

The rundown of 12 Best IVF specialists in Bangalore incorporate Dr. Archana Agarwal, Dr. Asha S Vijay, Dr. Sunil Eshwar, Dr. Rizwana Tasneem, Dr. Kamini Arvind Rao, and Dr. Vijaykumar PK to give some examples. You can discover other best infertility specialists in Bangalore with progress rates and IVF bundle costs.

IVF is a strategy for treating infertility-powerlessness to consider following a few years of endeavoring. This is a reality that the two people have an equivalent probability of experiencing infertility issues. Because of expanded work weight, wild and quick paced urban way of life with stress, ecological contamination, and postponing eligible age - the odds of infertility are rising essentially.

Some of the time, it might occur with numerous couples that infertility can cause more disappointment and sadness in a couple. Along these lines, it is imperative to pick a fertility treatment process that gives you affirmation. Infertility specialists are called Gynecologists who have been uncommonly prepared in the propelled methods in helping generation in barren and sub-ripe couples and give best IVF treatment in Bangalore.

We have recorded some Best Fertility Doctor in Bangalore:

Dr. Archana Agarwal is an infertility specialist, gynecologist and conceptive endocrinologist (infertility) in Marathahalli, Bangalore and has an encounter of 14 years in these fields. The specialist finished MBBS from MLB Medical College, Jhansi in 1991 and DGO from MLB Medical College, Jhansi in 1997. As of now, She is rehearsing at Mannat Fertility Clinic, Bangalore. The specialist is an individual from Karnataka Medical Council, Delhi Medical Council, Indian Fertility Society (IFS), Indian Society for Assisted Reproduction (ISAR) and European Society of Human Reproduction and Embryology (ESHRE). Your pursuit is finished on the off chance that you are discovering best IVF in Bangalore.

Dr. Chitra Ramamurthy

Dr. Chitra Ramamurthy is a Gynecologist in JP Nagar 6 Phase, Bangalore and has an encounter of 37 years in this field. She finished MD - Obstetrics, and Gynecology from Bangalore University in 1983 and MBBS from Karnataka University in 1980. She is rehearsing at Bingis Heart Care and Fertility Center, Bangalore. Being one of the well known IVF specialist in Bangalore she gives benefits In-Vitro Fertilization (IVF) and Intra-Uterine Insemination (IUI) and so forth.

Dr. Shilpa G B

Dr. Shilpa GB is a Consultant Gynecologist at Shanthi Nursing Home, Bangalore. She offers administrations like Ultrasonography, Lab Investigations, Pap smear, Infertility Work Up, IUI, Contraception, Antenatal Care, and Breast Cancer Screening. She finished MS from JJM Medical College, Davangere in 2005 and DNB (Obstetrics and Gynecology) in 2006. She additionally got preparing in IVF and Infertility from NUH, Singapore. Dr. Shilpa is a regarded individual from Bangalore Society of Obstetrics and Gynecology (BSOG), MNAMS, and Indian Society of Colposcopy. She has various accomplishments surprisingly, for example, GOLD Medal in MBBS, Gold Medal in OBG in 2005, and she has additionally gotten a cooperation in Maternal and Child Health, NARCHI. She is right now working at Bloom Clinic, Bangalore.

Dr. Vijay Kumar P.K

Dr. Vijay Kumar PK is a gynecologist and extraordinary compared to other IVF specialist in Bangalore with most astounding IVF achievement rates. His specialized topics involve Infertility, Obstetrics, and Gynecology. The administrations given by the specialist incorporates Intrauterine Insemination (IUI), Natural Cycle IVF, Preimplantation Genetic Diagnosis (PGD), In Vitro Fertilization (Test Tube Baby), Egg Donor, Gestational Surrogacy, Fertility Preservation, Endoscopy, Embryo Adoption, and Laparoscopic Surgery.He finished MBBS from University of Gulbarga and MD (Obstetrics and Gynecology) from Mumbai University. He further did his DNB in Infertility at Institute of Reproductive prescription from Kolkata. Your inquiry is finished on the off chance that you are discovering best IVF in Bangalore. He is rehearsing at Vardhan Fertility and Laparoscopy Center, Bangalore.

Dr. Vidyamani Lingegowda

Dr. Vidyamani Lingegowda is one of the most senior and experienced gynecologists in Bangalore and Karnataka today. A beneficiary of the renowned Rajyotsava Award presented by the Govt. of Karnataka, she has devoted her expert life to the persistent headway of ladies' social insurance. Subsequent to finishing her essential restorative degree at the University of Madras in 1972, she went to the United Kingdom to seek after post-graduation in obstetrics and gynecology.

Dr. Aviva Pinto Rodrigue

Dr. Aviva Pinto Rodrigue is a Gynecologist, Consultant Physician and Infertility Specialist in Richmond Town, Bangalore and has an encounter of 28 years in these fields as she is one of the well known IVF specialist in Bangalore. She finished MBBS from Bangalore University in 1989, MD - Obstetrics, and Gynecology from Bangalore University in 1993 and Diploma Reproductive Medicine from Germany in 2011. She is an individual from Federation of Obstetric and Gynecological Societies of India (FOGSI). A portion of the administrations given by the specialist are Ultrasound Scan, Donor Insemination Surrogacy, Ultrasonography - Pelvic, Natural Cycle IVF and Endometrial Receptivity Assay, and so on.

If you have any double about Best Fertility Doctor in Bangalore. You can contact us  

+91-8929020600

Elawoman

Please Follow Social links:-

                                                          Ela Facebook             Ela Twitter             Ela Instagram        Ela Linkedin        Ela  Youtube

[newssplashy]

World: Good news for women with breast cancer: many don't need chemo

Many women with early-stage breast cancer who would receive chemotherapy under current standards do not actually need it, according to a major international study that is expected to quickly change medical treatment.

“We can spare thousands and thousands of women from getting toxic treatment that really wouldn’t benefit them,” said Dr. Ingrid A. Mayer, from Vanderbilt University Medical Center, an author of the study. “This is very powerful. It really changes the standard of care.”

The study found that gene tests on tumor samples were able to identify women who could safely skip chemotherapy and take only a drug that blocks the hormone estrogen or stops the body from making it. The hormone-blocking drug tamoxifen and related medicines, called endocrine therapy, have become an essential part of treatment for most women because they lower the risks of recurrence, new breast tumors and death from the disease.

“I think this is a very significant advance,” said Dr. Larry Norton, of Memorial Sloan Kettering Cancer Center in New York. He is not an author of the study, but his hospital participated. “I’ll be able to look people in the eye and say, ‘We analyzed your tumor, you have a really good prognosis and you actually don’t need chemotherapy.’ That’s a nice thing to be able to say to somebody.”

The findings apply to about 60,000 women a year in the United States, according to Dr. Joseph A. Sparano of Montefiore Medical Center in New York, the leader of the study.

“The results indicate that now we can spare chemotherapy in about 70 percent of patients who would be potential candidates for it based on clinical features,” Sparano said.

But Sparano and Mayer added a note of caution: The data indicated that some women 50 and younger might benefit from chemo even if gene-test results suggested otherwise. It is not clear why. But those women require especially careful consultation, they said. (Most cases of breast cancer occur in older women: The median age at diagnosis in the United States is 62.)

The study, called TAILORx, is being published by The New England Journal of Medicine and was to be presented Sunday at a meeting of the American Society of Clinical Oncology in Chicago. The study began in 2006 and was paid for by the U.S. and Canadian governments and philanthropic groups. Genomic Health, the company that makes the gene test, helped pay after 2016.

This year, about 260,000 new cases of breast cancer are expected in women in the United States, and 41,000 deaths. Globally, the most recent figures are from 2012, when there were 1.7 million new cases and more than half a million deaths.

Chemotherapy can save lives, but has serious risks that make it important to avoid treatment if it is not needed. In addition to the hair loss and nausea that patients dread, chemo can cause heart and nerve damage, leave patients vulnerable to infection and increase the risk of leukemia later in life. TAILORx is part of a wider effort to fine-tune treatments and spare patients from harsh side effects whenever possible.

Endocrine therapy also has side effects, which can include hot flashes and other symptoms of menopause, weight gain and pain in joints and muscles. Tamoxifen can increase the risk of cancer of the uterus.

Patients affected by the new findings include women who, like most in the study, have early-stage breast tumors measuring 1 to 5 centimeters that have not spread to lymph nodes; are sensitive to estrogen; test negative for a protein called HER2; and have a score of 11 to 25 on a widely used test that gauges the activity of a panel of genes involved in cancer recurrence.

The gene test, called Oncotype DX Breast Cancer Assay, is the focus of the study. Other gene assays exist, but this one is the most widely used in the United States. It is performed on tumor samples after surgery, to help determine whether chemo would help. The test is generally done for early-stage disease, not more advanced tumors that clearly need chemo because they have spread to lymph nodes or beyond.

The test, available since 2004, gives scores from 0 to 100. It costs about $3,000, and insurance usually covers it. Previous research has shown that scores 10 and under do not call for chemotherapy, and scores over 25 do.

But most women who are eligible for the test have scores from 11 to 25, which are considered intermediate.

“This has been one of the large unanswered questions in breast cancer management in recent times, what to do with patients with intermediate scores,” Norton said. “What to do has been totally unknown.” He added, “A lot of patients in that range are getting chemo.”

Sparano said many patients have been receiving chemo because in 2000 the National Cancer Institute recommended it for most women, even those whose disease had not spread to lymph nodes, based on studies showing it could prevent the cancer from recurring elsewhere in the body and becoming incurable.

“Recurrences were being prevented, and lives prolonged,” Sparano said. “But we were probably overtreating a lot of these women. For every 100 women we were treating, we were probably preventing about four distant recurrences.”

Mayer said, “We couldn’t figure out who we really needed to treat.”

The availability of the gene test in 2004 helped researchers sort out women with very high or very low risk.

“But we really didn’t know what to do with women in the middle,” Mayer said. “Some seemed to benefit and some didn’t. We were back to square zero, safe rather than sorry, giving chemo to a lot who didn’t need it.”

Data began to emerge suggesting that women in the middle were not being helped by chemo, and many doctors began recommending it less often. But a definitive study was needed, which is how TAILORx came about.

The study began in 2006 and eventually included 10,253 women ages 18 to 75. Of the 9,719 patients with complete follow-up information, 70 percent had scores of 11 to 25 on the gene test. They had surgery and radiation, and then were assigned at random to receive either endocrine therapy alone, or endocrine therapy plus chemo. The median follow-up was more than seven years.

Over time, the two groups fared equally well. Chemo had no advantage. After nine years, 93.9 percent were still alive in the endocrine-only group, versus 93.8 percent in those who also got chemo. In the endocrine group, 83.3 percent were free of invasive disease, compared with 84.3 percent who got both treatments. There were no significant differences.

But the researchers wrote that the chemotherapy benefit varied with the combination of recurrence score and age, “with some benefit of chemotherapy found in women 50 years of age or younger with a recurrence score of 16 to 25.”

Bari Brooks, 58, a patient of Mayer’s from White House, Tennessee, learned from a mammogram that she had breast cancer in 2009 when she was 49. Mayer told her she was a candidate for chemo, and also for the study — in which she might or might not get chemo.

Could she handle the risk of missing out on a treatment that might save her life? Or the risk of side effects that might be needless?

“It wasn’t even a decision I had to think about,” said Brooks, who works in human relations for Vanderbilt University. “It was yes, I want to do it.” She added: “You realize how insignificant everything is. Money, it doesn’t matter how much you have. Work, what projects you have, it doesn’t matter. What have I contributed in my life and what do I want to contribute? This was a situation where I could also contribute. I was honored and grateful to be part of it.”

She decided that if she was assigned to chemo, “I would approach it that I was being cleansed rather than poisoned.”

She did land in the group that got both chemo and endocrine therapy. Did the chemo help? Maybe, maybe not. She has no regrets. And no evidence of cancer.

Mayer said that Brooks’ philosophical attitude was not unusual, and that women who signed up for studies understood they were taking a leap of faith and might wind up getting the ‘wrong’ or less desirable treatment.

“They’re grateful that they helped to advance knowledge for other women,” Mayer said. “I never underestimate how nice and how altruistic people can be. Women look out for each other.”

This article originally appeared in The New York Times.

DENISE GRADY © 2018 The New York Times

source https://www.newssplashy.com/2018/06/world-good-news-for-women-with-breast_4.html

[wefreestudentpostworld-blog]

An ectopic pregnancies occur when a fertilized eggs implanting somewhere other than the main cavity of uterus. Pregnancies start with a fertilized egg. Normally the fertilized egg attached itself to the lining of the uterus. An ectopic pregnancy most often occurs in one of the tube that carries eggs from the ovaries to the uterus fallopian tubes. This type of ectopic pregnancies is known as a tubal pregnancy. In options some cases however an ectopic pregnancy occurs in the abdominal cavity ovaries or else somewhere near neck of the uterus cervix.

An ectopic pregnancy can't proceed normally. The fertilized eggs cannot survive and the growing tissue might destroy various maternal structures. Left untreated life threatened blood losses is possible. Early treatment of an ectopic pregnancy can help preserve the chance for future healthy pregnancies. Normal pregnancies your ovary release an egg into fallopian tube. If the egg met with a sperms and fertilized eggs move into your uterus to attach to its lining and continues to grow for next 9 month.

Ectopic pregnancies occur when the fertilized eggs attached in itself in a places other than inside the uterus. Almost all ectopic pregnancy occur in the fallopian tubes are thus sometime called as a tubal pregnancy. The fallopian tubes are not designed to hold a growing embryo .the fertilize egg in a tubal pregnancies cannot developed in a proper manner and must be treated. An ectopic pregnancies happens in 1/50 pregnancies. In any case instead of pregnancy find life is in danger. Ectopic pregnancies require emergency treatment.

Most often ectopic pregnancies happened within the first few week of pregnancy. You might not even know you are pregnant yet so it can be a big shock Doctors usually discover it by the 8th week of pregnancies.

Ectopic pregnancy make scared and sad. The baby probably cannot survive though in extremely rare case he or she might. This is not possible in a tubal pregnancy corneal or cervical so it is a loss that may take some time to get over. It may comfort you to know that if you have ectopic pregnancies you will likely be able to have a healthy pregnancy in the future. The characteristic three symptoms of ectopic pregnancy are

First mainly an ectopic pregnancy might not cause any symptoms. Early signs and symptoms of an ectopic pregnancy might be the same as those of any pregnancies miss periods breast nausea and tenderness.

If you take a pregnancy test results will be positive. Still an ectopic pregnancy cannot continue as normal.

Light vaginal bleeding with abdominal or pelvic pain is often the first warning signs of an ectopic pregnancy. In Any situation blood leaks from the fallopian tube it is also possible to feel shoulder pain or an urge to have a bowel movement depend on where the blood pools or which nerve are irritates. If the fallopian tubes rupture heavy bleedings inside the abdomen is likely followed by lightheadedness, fainting and shock. Only about 50 percentages of women have all three of these symptoms. Risk factors for ectopic pregnancies include previous ectopic pregnancies and conditions surgery infections that disrupt the normal anatomy of the Fallopian tubes.

The major health risk of ectopic pregnancies is rupturing and leading to internal bleeding .Ectopic pregnancy occurs in one to two percent of all pregnancy. Diagnosis of ectopic pregnancy usually established by blood hormone test and pelvic ultrasound.

Many women are concerns about having a pregnancy complication. Ectopic pregnancies are a very serious one. Whether you think that you may have ectopic pregnancies with concerned partners or friends are just curious may have many questions. There are some of the most common questions we hear women ask about ectopic pregnancy.

When to consult doctor if any emergencies during ectopic pregnancy

Severe abdominal or pelvic pain     accompanied by vaginal bleeding

Extreme lightheadedness or     fainting

Shoulder pain

Treatment

Ectopic pregnancy is life-threatening. The pregnancy cannot continue to birth term. The developed cells must be remove to save the mother life.

You will need emergency medical help if the area of the ectopic pregnancies breaks open rupture. Rupture can lead to bleeding and shock, an emergency condition. Treatment for shock may include. If there is a ruptured surgeries is done to stop blood loss and remove the pregnancy. In some case the doctor may have to take out the Fallopian tubes.

    Surgery

    Medicine that ends the pregnancy, along with close monitoring by your doctor

    Blood transfuse

    Fluids give through veins.

    Keeping warm

    Oxygen

    Raising the legs.

   http://drandalslakshmifertilityclinic.com/