#b/c they can interfere with each other's absorption
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and just as a heads up, that is why you should actually read the whole attached tiny print information packet that comes with your meds even though you think you already know it
and also when they ask if you have questions for the pharmacist say "yes" and ask if there are any food or drug interactions you should be aware of
i know vitamin c basically neutralizes adhd meds but lemonade good
#sincerely: I was dumb and combined caffeine with adhd meds the first time I took them#sincerely also: I am on like 4 different vitamins and meds prescriptions rn and I have to take them all different times of day#b/c they can interfere with each other's absorption#turns out don't take your calcium and iron at the same time#etc
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Treating Small Bowel Cancer: A Comprehensive Approach
Introduction:
Small bowel cancer, although relatively rare, poses significant challenges due to its location and limited treatment options. The small bowel, also known as the small intestine, plays a crucial role in the digestion and absorption of nutrients. When cancer develops in this vital organ, prompt and appropriate treatment becomes crucial. In this article, we will explore the various treatment options available for small bowel cancer, highlighting both surgical and non-surgical approaches that can help patients achieve the best possible outcomes.
Surgical Interventions:
Surgery is often the primary treatment for small bowel cancer. The choice of surgical procedure depends on factors such as the tumor's size, location, and stage. Some commonly used surgical interventions include:
a) Resection: Surgical removal of the cancerous portion of the small intestine, along with nearby lymph nodes, is a standard approach. In cases where the tumor is limited, a partial small bowel resection may be performed. If the cancer has spread extensively, a more extensive resection might be required.
b) Lymphadenectomy: Removing nearby lymph nodes helps prevent the spread of cancer and allows for a more accurate staging of the disease.
c) Surgical bypass: When a tumor obstructs the small bowel, surgeons may create an alternative pathway to bypass the blockage, allowing for the continuation of normal bowel function.
Radiation Therapy:
Radiation therapy utilizes high-energy beams to target and destroy cancer cells. It can be administered externally or internally. In small bowel cancer treatment, radiation therapy is often used in combination with surgery or as a palliative measure to relieve symptoms when the cancer is advanced. The precise use of radiation therapy depends on individual factors and the extent of the disease.
Chemotherapy:
Chemotherapy involves the use of powerful drugs that circulate throughout the body to kill cancer cells. It can be administered before surgery to shrink tumors, after surgery to eliminate any remaining cancer cells, or as a primary treatment option for advanced cases. Chemotherapy may be used in combination with other treatments to achieve better results.
Targeted Therapy:
Targeted therapies aim to interfere with specific molecules or pathways involved in cancer growth and progression. In small bowel cancer, targeted therapies like tyrosine kinase inhibitors may be used to inhibit the activity of specific proteins that promote tumor growth. These treatments are typically recommended for advanced or metastatic cases.
Immunotherapy:
Immunotherapy is a groundbreaking treatment option that stimulates the body's immune system to recognize and attack cancer cells. While it has shown remarkable success in various cancers, its effectiveness in small bowel cancer is still under investigation. Clinical trials are ongoing to explore the potential of immunotherapeutic approaches for small bowel cancer treatment.
Palliative Care:
For patients with advanced small bowel cancer or those who cannot undergo aggressive treatment, palliative care becomes essential. Palliative care focuses on managing symptoms, improving quality of life, and providing emotional support. It may include pain management, nutritional support, and psychological counseling.
Conclusion:
The treatment of small bowel cancer requires a multidisciplinary approach tailored to each patient's specific circumstances. Surgical interventions, radiation therapy, chemotherapy, targeted therapy, and immunotherapy are the key treatment modalities available. The choice of treatment depends on factors such as tumor stage, location, and individual patient factors. By combining these treatment options and integrating palliative care when needed, healthcare professionals can provide the best possible outcomes and improved quality of life for patients affected by small bowel cancer.
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The Health Benefits Of A Multivitamin Supplement
A multivitamin is a dietary supplement that contains a variety of vitamins and minerals. These nutrients are essential for the body to function properly. Some people choose to take a multivitamin as an insurance policy against potential deficiencies, while others take them for the health benefits they offer. In this article, we’ll explore some of the health benefits of taking a multivitamin supplement like activin.
What are the health benefits of a multivitamin supplement?
A multivitamin supplement can provide some health benefits, such as a decrease in the risk of certain diseases. A 2009 study published in "The Journal of the American Medical Association" found that people who took a multivitamin had a 37 percent lower risk of death from any cause than those who didn't take one. The study followed more than 72,000 people for an average of 10 years.
Another benefit of taking a multivitamin is that it can help keep your body healthy overall. According to the Centers for Disease Control and Prevention (CDC), people who take a multivitamin have a lower risk of developing various types of cancer, including ovarian, prostate, and colorectal cancers. Additionally, taking a multivitamin may help reduce your risk of heart disease by protecting your heart cells from damage.
What are some common ingredients in multivitamin supplements?
Multivitamin supplements typically contain a variety of B vitamins, including thiamin (B1), riboflavin (B2), niacin (B3), and vitamin B6. They may also include vitamin C and other minerals and phytonutrients.
Some studies have suggested that multivitamins may help to reduce the risk of some health conditions, such as heart disease, stroke, cancer, and arthritis. In addition, multivitamin supplements may help to improve overall health by helping to maintain a healthy weight and reducing the risk of chronic diseases.Some common ingredients in multivitamin supplements are vitamin A, vitamin C, thiamin, riboflavin, niacin, vitamin B6, and folate. Vitamins A and C help protect the body from damage caused by the sun and other environmental factors. Thiamin helps to convert food into energy and riboflavin helps to produce red blood cells. Niacin is important for the production of cholesterol and cell membranes. Vitamin B6 is necessary for the production of DNA and neurotransmitters. Folate is important for DNA synthesis and nerve function.
How to take a multivitamin supplement
Taking a multivitamin supplement can provide several health benefits, including reducing the risk of heart disease and some types of cancer.
To be effective, a multivitamin should contain at least 400 micrograms (mcg) of vitamin B6 per day. It's also important to make sure the supplements you take are absorbed well, as many multivitamins are formulated with binders that can reduce absorption.
Some people prefer to take their multivitamins with food to increase absorption rates. However, it's important to be aware that certain foods (such as iron-rich meat) can interfere with the absorption of certain vitamins and minerals. Therefore, it's always best to speak with your healthcare provider before starting a multivitamin supplement regimen.
How long should a person take a multivitamin supplement for?
A multivitamin supplement can provide a host of health benefits, including reducing the risk of certain diseases. There is no set length for how long a person should take a multivitamin supplement, as each person’s needs vary. However, many experts recommend taking a multivitamin every day to ensure optimal health.
Tips on how to tell if you're getting the right amount of vitamins and minerals
There are countless benefits of taking a multivitamin supplement, but knowing how to tell if you're getting the right amount of vitamins and minerals can be confusing. Here are five tips to help you get the most out of your multivitamin:
1. Consider your diet. A good way to determine how much nutrients you're missing is to look at your diet. If you're not getting enough of certain vitamins and minerals, supplementation may be necessary.
2. Check with a doctor. If you have any health concerns, such as kidney or liver disease, discuss taking a multivitamin with your doctor before starting the supplementation process.
3. Be aware of potential side effects. While most multivitamins are safe for daily use, there are always potential side effects that should be noted by consumers before starting any new supplement regimen. Always consult with a healthcare professional before starting any new supplement regimen in order to ensure safety and effectiveness.
4. Follow the dosage instructions on the product label carefully. Every multivitamin has its own recommended dosage, so make sure to follow these instructions carefully in order to get the most benefit from the supplement. As with any medication or supplements, it's always best to speak with a healthcare professional before starting any new supplementation regime in order to ensure safety and efficacy.
5. Take breaks between doses. It's important not to take multivitamins continuously for extended periods of time in order to prevent potential nutrient depletion or overdose. Take breaks between doses in order to allow your body to replenish and balance its own nutrient levels.
Conclusion
According to Dr Uribe , taking a multivitamin supplement can have a host of benefits for your health. By including one in your daily routine, you are ensuring that your body is getting the essential vitamins and minerals it needs to function at its best. Not only will this help improve your general health, but it can also ward off some common diseases. So don’t wait any longer – get yourself a multivitamin supplement today!
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Basic Undertale AU Info- RandomizerTale
The Story
With each reset everyone (other than frisk/chara, gaster, and maybe flowey) are randomized as different character roles. The characters still look the same and have the same names, but they act and talk as the characters they are playing as. They still have their same basic powers (except for sans who can't maintain his knowledge of resets outside his role), they just act different.
Think of it as a randomizer mod. The same art and battle assets, just different dialogue.
Sans gets nerfed for whoever he's playing as though.
The only one who realizes is the character playing as sans. Since the sans has an unnatural ability to remember every resets, this ability is transferred to who is sans and gets multiplied as they'll remember not only the pov of every sans before, but of their own povs as other characters as well. This multiplication increases exponentially to the point that sans is basically an amalgamation of everyone's povs in the underground.
The Sanses are also proficient in all types of magic now (as the body allows of course [if in Sans bod he still tired with 1hp bro and Undyne sans is an absolute BEAST] and depending on who else has been sans before). This means that genocide fights get progressively harder and harder each time a reset happens and dialogue changes too depending on who is playing sans (pap genocides usually end pretty fast though [despite everything he thinks the human can do better]).
Eventually the randomization just so happens to land on the original configuration of monsters. Seeing his chance for it to go back to normal, Sans, ��with everyone's pov of the resets, teleports to frisk at the beginning of the route and confronts/begs frisk to stop the madness: pleading them to be better person (paps), to stop hurting the ones they love, to let them to finally live on the surface instead of just looking at it, to just stop the resets altogether and to let this be their final reset.
After the final reset, Sans is still sans but he has EVERY monsters pov of past resets (boss and minor monster alike). Once the resets end, he isn't everyone shoved into one body, but sans with a recollection of everyone's pov of past resets. IT IS NOT D.I.D!!!! Of course he knows that he himself is sans, but he might have random episodes where he does/says things that other characters would say/like/do (ex: pose like mettaton, make a puzzle, gush like alphys over his interests, drink tea...you get the idea) due to him being forced to play as other characters in other resets. (Other chars in the au don't have this happen to them cause they don't remember previous resets)
When he is talking about past experiences during the resets, he flips between pronouns and from first/third person (I, we, she, he, they) in order to get some of feelings across (I as Sans, we as everyone's pov of resets, and others as specific people's povs).
“Episodes”:
His episodes can be broken by a) someone telling him that's not how he is, b) physical interference (ex: slap, tripping, sleep), c) him having a dissociating moment where he's like “wait a minute...”, and d) he finishes the action the episodes requires of him.
Some episodes are harder to recognize (specially ones with no final action/goal in mind. For example: getting anxious over social interaction like alphys vs making a butterscotch pie.) Episodes don't overlap each other, so he could be his sans personality while making a pie, making different jokes based on an interest change, or just extruding mettaton confidence/self-absorption).
There are certain episodes that he doesn't mind very often and will actually complete it even after he breaks out of it, specifically the task episodes like making pie/spaghetti/tea. He's learned to really like that stuff.
Some episodes that he particularly hates are when he acts/speaks like mettaton or temmie, nervously word vomits like alphys (cause there's no filter and he can say stuff he doesn't want to be said out loud [he a secretive guy]), and when he acts like Jerry because eewwwwww.
To apologize or explain his behavior after an episode he calls it the (insert character) in me or my inner (insert character). "welp my inner toriel came out again..." "sorry, kiddo, that was just the undyne in me..."
Ones he hates or are improperly timed, he sometimes just insults the characters though. "f-ing mettaton..." "alphys I like you but whyyyyyy" "*gags* ...Jerry"
Types of episodes: social (acting or talking like someone), thoughts (interests or ideals) (he HATES this one the most as it makes him feel less like him), physical (task or long-lasting [long-lasting like dancing/ posing/working out]). (Keep in mind that social and physical episodes keep sans ideas/thoughts/interests intact, he just communicates them in a way another character would say them.) Specific social or physical episodes can be triggered with high emotions (though most of the time it's just random). Extreme anger can bring out the undyne in him, fear/nervousness alphys, adoration paps, depression nabstablook, worried for someone else toriel, and so on.
Some Fun Facts:
Fun facts: Sans gets headaches after an episode where he acts/thinks like someone else. The severity usually depends on how long the episode is and how out of character is for him.
Fun facts 2: Following the logic of post reset sans, other characters playing as sans will think and act like the original char they are supposed to be but with sans personality. Unless episodes happen... (EX: Toriel goat jokes, undyne fish jokes.) So it leads to different character interactions where an undyne sans is more pissed off at frisk and more prone to violence. Paps sans more encouraging to be a better person. Other chars as sans also get episodes and headaches if they act like other chars other than themselves (disregarding sans cause they are supposed to be sans.). Bruh does this get complicated...
Fun facts 3: The other char’s povs only start once frisk falls underground so sans doesn't know how toriel felt leaving ashore or pap waiting outside undyne’s house to join the royal guard. That means his episodes and knowledge of others chars reset feelings/actions during povs are strictly based upon the duration the timeframe that frisk is underground.
Fun facts.4: The sanses in all the reset always has a soft spot for paps. They know that he ain't their bro but the code just has that as a priority for the sans. (Paps as sans is like my bro loves me ;n;.) They enjoy it when paps is playing alphys in genocide routes cause at least they know he won't die that route.
Fun facts 5: In an alternate version of this au when frisk ignores sans's plea for it to be their final route, sans would most likely snap and go crazy and just straight up try to murder the kid over and over again regardless if they were going to do a pacifist or geno route until they agree to his terms or until he dies (and he'll do it for all future resets [except for maybe pap sans???]) Who knows a Dusttale (see @ask-dusttale ) might even happen but the version of sans would feel less guilty bout it cause most other char povs would only confirm that other characters would just want frisk to suffer.
Fun fact 6: In another happier alternate version of this au, a version of sans confronts frisk earlier on, making them feel bad early and just wants everyone to go back to normal. So they constantly reset until they find the normal config for the final reset. The Sanses in this route are pretty chummy with frisk. They are very tired of the resets regardless though (as it takes forever to land on the normal configuration) and sometimes halfheartedly bets with frisk who the next sans is going to be. The resets where everything is normal except for one monster are especially soul crushing for both the Sanses and frisk. They were so close!!!!!
Designs:
For the design of another chars as sans they might go out of their way in the assets and wear sans classic jacket to showcase that they are a sans and are aware of what's going on. So their normal outfits but with sans jacket on top.
Interesting info of probability of a normal config happening in the randomizer:
~58 enemy types so 3364 (0.000297265% of normal config)
Or
~322 monsters total so 103684 configurations (0.0000096446896% of normal config)
(let me know if I did the math incorrectly :) )
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Life without COFFEE
Although I am not one of those people who find themselves unable to work in the morning without daily caffeine intake,
I love the warm kind that makes me feel the happiness that coffee provides me. Life is full of delicate pleasures, as I like to call it, and coffee is one of my countries. However, as I write this, I am about to start my (fourth) experience "A Month Without Coffee". Well, it's not a big experiment, but it's more of a "habit" control. I used to drink up to six cups a day in January, and for me, this is too much. People just say, drink less. No need to give it up completely. Why are you doing that? She loves coffee. I love coffee. I love coffee! It is not bad advice. When giving up caffeine, or any other addictive substance, it is advised to reduce it gradually rather than absolutely nothing to minimize withdrawal symptoms... but I can't do that. I am not an "admin". All or nothing, I find it easier this way. So I'm going to go from six cups today, to zero tomorrow, and that's how you'll stay for the next 28 days. I think you can change your habits by knowing what drives your behavior. Take a few seconds to ask yourself why you're about to drink something. You always have a reason why you should make the choices you make, and when you drink a lot throughout the day, paying attention to whether this reason is productive or unproductive for your health is worth doing. I think of 4 reasons why I chose to choose coffee. Socially (Meet a friend for coffee) - For warmth - For strategic reasons (just before training) - For fun (I just love coffee time) I am sure you have other reasons to add it. "Addict" was not shown on my list, as I do not think I am "addicted" or "dependent" on coffee, or anything else in this regard. I think another reason to give up is not only due to serious health considerations, but also to prove to myself that coffee is not controlling me, I choose to drink it, and it can stop at any time. All I have to do is replace my coffee with a drink that rewards me in the same way, and this is much better for my health. Another way to control what you drink is to look for signs that make you choose: a specific time of day (such as morning), a particular place (such as Starbucks), when you are with certain people (for example your co-workers), or emotion (such as feeling tired) ), Or ritual behavior (such as waking up with coffee). Caffeine cut, but not ritual! Delicious alternatives that I will share with my caffeine habit: Lemon Juice and Warm Water: Warm water and lemon help detoxify the liver and kidneys from caffeine and the overload of coffee caused by the system. Herbal Tea (Caffeine Free): Peppermint is a stimulant, good for digestion while chamomile is soothing, good for stress and migraine headaches. Root tea: Licorice is useful to support the kidneys in times of stress and is a natural stimulant and ginger that helps mild headaches and digestion, as it is naturally stimulating. What happened the last time you did this? My memories were of the first few days of a very severe headache that peaked from day two to day four. After that, it was easy, and even when the 30 days were up, I didn't know if I wanted coffee or not. I found alternatives that are now part of my daily nutrition and have seen no rush to come back. But since I had never intended to give up coffee completely, slowly but surely, I crept into my work routine. Some days it was three, four others, five or six, depending on my location. Caffeine, like any drug that has different effects on different people, as I discovered, is linked to specific genes. Common symptoms are irritation, dehydration, fatigue, muscle tension, nausea, constipation, and lack of focus. Reducing withdrawal caffeine weakens adrenal, and liver functions and the acidic effect of coffee on the system can gradually deplete the body's general ability to flush out toxins and maintain an appropriate acid balance. By getting rid of caffeine, your body will start doing this to remove accumulated toxins and restore adrenal and liver functions. We have many things you can do to help support your system and help detoxify, as well as reduce drag systems. Lifestyle changes to the caffeine vitamin Drink plenty of water, at least 9 cups per day. Get plenty of good sleep. You are playing sports. I will help you detoxify and give you more energy naturally. Steam baths, leather brushes, and English salt baths help pull toxins through the skin. Nutrient foods: Eat foods rich in whole nutrients - fruits, vegetables, legumes, proteins, healthy fats, and grains rich in fiber. Fiber helps transfer toxins from your body and will stabilize the digestion process, which can be disrupted when caffeine is removed. Fruits and vegetables will help reduce the impact of acidifying coffee on the body, and will also help flush toxins out of your system. Avoid processed foods, sugars, and salt as they will cause your body to retain fluids. Add additional fiber supplements, such as flax, chia, or psyllium husk, to help detoxify the liver, kidneys, and intestines. Maca: It is a natural source of amino acids, essential fatty acids, vitamins and carbohydrates, and helps your body produce energy naturally, without any side effects from adrenal drainage. Add juices or sweets or stir in porridge or milk. Spirulina: a powerful microalga that removes toxins and is a good source of natural energy. It provides many essential nutrients and rare minerals to support your system, and it is surprisingly rich in protein. Add to green juices or in tablet form. Supplements when giving up caffeine (and adrenal gland) The liver is responsible for breaking down caffeine from the body. It is advisable to take a dietary supplement to assist it during this detoxing process. These include: Milk thistle magnesium Calcium Potassium zinc B vitamins Vitamin C So, because it seems, the foremost of the items I like to recommend to attenuate the effect of withdrawal symptoms, I do daily anyway, so apart from the standard behavior, I expect it to be relatively painless. The next question was, why? If I like coffee such a lot, why did you spend 28 days without it? In any case, the superb coffee for you... or is it? Yes and No. Thousands of studies need to be conducted on the consequences of caffeine over the past fifty years, one against another. The consensus seems to be that moderate (high-quality) coffee consumption is often more beneficial in many health indicators than none in the least. But what's "moderate". Again, the research varies counting on what you read, but the range appears to be between 300-400 mg of caffeine, as a maximum per day. It equates to 3 to four cups of coffee (depending on strength and size). Other reports recommend a maximum of two. As I said earlier, caffeine has different effects on different people, so it's difficult to answer. While I drank up to 6 each day and drank caffeine from other things, albeit in small amounts (from dark chocolate), it had been time to rest my body. The dangers of excessive caffeine in your system Calcium Caffeine causes calcium to be excreted within the urine and feces. For each 150 mg of ingested caffeine, approximately 5 mg of calcium is lost in one cup of coffee. This effect occurs even hours after consuming caffeine. Caffeine also blocks the quantity of calcium that's absorbed through the intestine and drains the amount kept by the bones. Tons of studies have shown that ladies who consume a better amount of caffeine have more hip fractures than those that avoid caffeine or drink moderately (1 to 2 cups per day). Vitamin D Caffeine blocks vitamin D receptors that limit the quantity which will be absorbed. Because vitamin D is essential in absorbing and using calcium in bone building, this will also reduce bone mineral density, which results in an increased risk of osteoporosis. iron As everyone knows, caffeine interferes with the absorption of iron from the body, which is essential for the assembly of red blood cells—drinking caffeine at an equivalent time because the iron source can reduce intake by up to 80%. Any caffeinated drink must be separated from iron-containing foods or supplements for a minimum of one hour. B vitamins As is understood, caffeine features a mild diuretic effect, which increases urination. Water-soluble vitamins, like B vitamins, are often depleted as a result of fluid loss. Additionally, it interferes with the metabolism of some B vitamins, like thiamine (Vitamin B1). The sole exception to the present rule seems to possess vitamin B12. It plays the catalyst role for caffeine to supply stomach acid, which helps the body absorb vitamin B12. Vitamins and other minerals All Vitamins and minerals are essential nutrients for normal cell function. Since it must be absorbed from the bloodstream to be effective, anything that impedes this process can cause the body to not getting enough nutrients. Caffeine can reduce the absorption of manganese, zinc, and copper. It also can increase the secretion of magnesium and potassium, sodium and phosphate minerals. There's also some evidence that caffeine interferes with the action of vitamin A. Your skin looks older. Skin needs tons of water to seem plump and glowing. But coffee may be a diuretic, which inspires your body to flush out water. If you drink tons of coffee, your skin may look dehydrated. If you flood your body with caffeine, this suggests that your systema nervosum has entered into an endless state of artificial stimulation. Therefore the skin is your largest organ and wishes oxygen-rich blood. When the body is in tension, it responds by directing the foremost oxygenated blood towards the guts and lungs. Therefore the skin isn't well-nourished. The systema lymphaticum, which removes waste, also doesn't function efficiently, leaving the skin slow and susceptible to burst. Cellulite Coffee can even be utilized in many anti-cellulite creams - applied to the skin from the surface, and toxins stored in fat cells are allegedly extracted to scale back cellulite - but this doesn't mean that drinking it'll have an equivalent positive effect. Coffee-induced dehydration encourages the skin to congest and solidify and to make a dense network that results in cellulite. Feel bad breath Like alcohol, coffee dries your mouth, and as a result, the quantity of saliva that rinses your mouth and fights bacteria decreases. We All Know that Caffeine can turn yellow teeth just like the same way as nicotine roll in the hay from cigarettes as coffee contains tannins, which are plant compounds that give coffee flavor. Coffee is extremely acidic, which over time can break down the enamel on the surface of the teeth. Diuretic effect You can't drink quite three cups of coffee each day features a diuretic effect on the body, because it interferes with the hormones that regulate our water balance. It leaves us dried and makes the urine more concentrated and acidic, which results in inflammation of the bladder walls and even results in painful urination and cystitis. Keep in mind that it takes five to 12 hours for the body to urge obviate caffeine, and once you sleep within the bed, you'll still be unable to sleep. Once washed away, coffee makes sleeping lighter and more annoying. It's because caffeine interferes with the assembly of melatonin, which helps us sleep. Every day is bad for the hair. Caffeine has been found to flush out vital minerals, including those needed for healthy hair growth, outside the body. Our body needs an honest supply of some vitamins and minerals for a reasonable condition of hair and pigmentation, including biotin, selenium, zinc, and copper. If we consume tons of coffee, this may affect our metal stores, which can hurt the condition of hair, including luster and texture. Metal loss may cause hair loss and premature greying. One of the most reasons for pre-menopausal hair loss is low iron levels and occasionally affects their absorption. Copper is believed to contribute to hair pigmentation so that any deficiency may cause premature greying. Insulin sensitivity decreases Regular consumption of caffeine reduces insulin sensitivity, making it difficult for your cells to reply appropriately to blood glucose. High blood glucose levels cause arterial degeneration and an increased risk of disorder. The acidity of coffee Coffee acidity is related to digestive discomfort, indigestion, heartburn, and intestinal disorders. addiction Addiction is usually a drag with coffee drinkers and makes it difficult to believe the body's natural energy source. Low levels of serotonin A component of the neurotransmitter serotonin referred to as the happy chemical present within the urine tends to be high in coffee drinkers, which suggests they'll be in danger of low levels of serotonin synthesis within the brain. Serotonin is essential for healthy sleep, bowel function, mood, and energy levels. It's a vicious circle because caffeine can disrupt sleep and promote anxiety and depression. We all know someone who tends to urge tired, wired and quit caffeine! Lots of reasons to chop back, or in my case, you've got an opportunity from caffeine altogether. It's essential to notice that a lot of the issues mentioned above relate to excessive caffeine consumption. I've also read tons of research on how moderate amounts can benefit our health and more if you drink at strategic times throughout the day. It's been linked to a lower risk of affected by Alzheimer's and paralysis agitans, for instance. Can you hand over your coffee? If you think that you cannot hand over coffee, re-evaluate. It's only a wise experience to understand what it seems like to measure your life on your fuel. Safely remove coffee and caffeine from your system and see how you handle the high energy! It'll not kill you. Sometimes we hold close our vices so severely that we convince ourselves that life would be miserable without them. For the first few days, I admit, I miss the smell and taste of my coffee, especially the first day of the day but these feelings soon disappear, and that I have gained a replacement appreciation for herb tea and roots. Remember that we control our habits. Getting something may be a big lesson in breaking addictions and forming new habits. You'll convince yourself that you directly are managing, and you'll choose and stick with it. This is often something you'll know.
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Taking Vitamin Supplements
Vitamin Supplements What to Know
Throughout the world, a lot of people have problems with their digestive systems that make it hard to absorb nutrients and break down the food they eat. This is a common problem, one that is usually caused by a poor level of acid in the stomach, toxic in the gut, or a lack of producing enzymes that assist with the breaking down process. There are other causes as well, although the above are the most common. Vitamins and Your Digestive Tract Problems with the digestive tract can be improved quite a bit if you slowly increase your intake of nutrients. A diet that is high in organic matter is the preferred way to improve your digestion, although you may need to use supplements as well. The best thing about supplements is the fact that you don’t need a prescription. You can select which ones you want on your own, and purchase them at your local nutrition store or online. Best Times to Take Supplements The ideal time to take supplements is with your meals. During this time, your body can absorb the nutrients better, as your digestive system will be stimulated with food. If you are using time-released supplements, you should take them with food to ensure that they move through your body at the right pace and release the proper amount of nutrients and vitamins your body needs at the right time. Water-soluble vitamins are the easiest to use, as they will pass through the body easily and quickly, and should be taken three times a day. Fat-soluble vitamins are best absorbed if they are taken with food that contains fat. You should always take vitamins with meals, as the minerals and nutrients found in food will work with vitamin supplements. A Possible Problem with Absorption Some supplements may interfere with others when you absorb them, so you should always make sure what you are taking is acceptable to take with other forms of vitamin supplements. Below, is a list of the most common vitamins and how you should go about taking them. 1. Vitamins A, D, and E - These vitamins should always be taken with meals that contain fat or oil. 2. Vitamin B - You should always take vitamin B supplements as soon as you wake up, to get the maximum benefit. You can also take them during the day with a whole grain meal. 3. Vitamin C - Supplements containing vitamin C should be taken with meals and never on an empty stomach. 4. Iron - Iron supplements should always be taken with food, as they are easy to absorb this way. 5. Multi-vitamins -You can take multi-vitamins at any time, although you should always consume a small meal with the supplement. Even though you may be on a healthy diet, you should still make sure that you are getting the proper vitamins and supplements as well. Supplements will help your body get the vitamins and minerals it needs, especially on days that you aren’t able to eat what you should. Life can get hectic at times, which is where supplements can come in handy. Always Follow Directions If you include supplements in your diet and take them correctly, you’ll find that your body will be much healthier. There are many different vitamins and supplements that you can take, although they will depend on what you are trying to achieve. You should always research a vitamin that you are interested in taking and make sure it fits your needs before you decide to purchase it. Vitamin Supplements Types Although getting the proper amount of vitamins and nutrients from natural food is important, it can be very hard to do. Those who can’t get the minerals and such they need from food, turn to vitamins and supplements. With vitamin supplements being a big business, there are many manufacturers to choose from. Each year, there are thousands of supplements out there, with customers spending billions and billions of dollars to get the supplements and vitamins they need. 3 Types of Supplements Right now, there are 3 different delivery systems for supplements – liquid, capsules, and tablets. Although each one is good in its own right, you should always pick one that dissolves easy and doesn’t just pass through your system. If your vitamin passes through your body, it will end up toilet and you’ll end up wasting your money. The liquid is considered to be the best, although there aren’t that many supplements or vitamins available in liquid form. The liquid is preferred by some, although others think of them as tasting like cough syrup. If you aren’t able to swallow pills or capsules, then the liquid would be a great alternative. The most common type of supplement is tablets. Tablets are created from organic cement then formed into shape. The only drawback here is dissolving. For tablets to dissolve properly, organic types of cement need to be used, although they cost quite a bit more, causing manufacturers to skip adding them. You can also find supplement tablets that have a coated shell, although they are normally found in the cheaper vitamin and supplement stores. The capsule type of vitamin supplements is preferred by many, as they dissolve quickly, normally faster than the other delivery systems. Due to the fact of them not being compressed like tablets, you’ll normally need to take two of them to get the same amount that’s provided with one tablet. Get the Best Amounts When you use vitamin supplements, you want to be sure that you are getting the most amounts possible. Vitamins are a great alternative to minerals and nutrients found in food and are ideal for those who aren’t able to eat the right foods. Vitamin supplements are also great for athletes or those looking for more energy, as they will supply the levels your body needs for exhaustive activity. You can buy your vitamin supplements on the Internet, or through a local nutrition store such as GNC. GNC is among the most popular in terms of local stores, as they carry hundreds and hundreds of vitamins and supplements. You can find everything from health vitamins to bodybuilding supplements. They have rock bottom prices with plenty of manufacturers, including the top name brands. With millions of dollars in revenue each year and over 100 chains throughout the United States, GNC is a dominant name in the world of vitamins and supplements. If you need to take vitamins or supplements but aren’t sure what you should take, you should consult with your doctor. Vitamins and supplements are a great way to get minerals and nutrients to your body, although they should never, ever, be used to replace food. You’ll still need to maintain a healthy diet, even though you may be taking vitamins. If you can maintain a healthy diet when taking your vitamins and supplements, you’ll find the benefits to be twice as good. When choosing your supplements you should always choose them wisely, making sure that you get exactly what you need. If you choose your vitamins and supplements wisely – you’ll find them to be the perfect addition to a healthy diet. You are not alone if you are experiencing anxiety today. Anxiety and other mental health problems are at an all-time high, according to Mental Health First Aid ...
Negative Thoughts-How to Clean the Mind
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Juniper Publishers-Open Access Journal of Environmental Sciences & Natural Resources
Distribution of Arsenic Species in Surface Water Using Flow Injection Hydride Generation Atomic Absorption Spectrometry and Furnace Method
Authored by Swapnila Roy
Abstract
Arsenic has been considered detrimental to human health when accumulated in the body beyond the tolerance level. The toxicity level of certain species (like As3+) of Arsenic is higher than others, making the situation worse for human health with its presence. In this study, we used a combination of two principal atomic absorption spectroscopic methods, namely Flame-FIAS and the Furnace technique, to determine the distribution of inorganic Arsenic species in a synthetic sample. The Flame-FIAS technique was employed to determine the amount of toxic As3+ present in the samples and the Furnace method was used to measure the total Arsenic content. Following standardization of this experimental process, we used the technique to determine the distribution of inorganic Arsenic species in environmental samples with high total Arsenic content. Since the samples were collected from surface water systems, the conditions are supposed to be oxidizing. As per the natural geochemical distribution phenomena of Arsenic species, As5+ was found predominantly (around the range of 10-18 μg/l) in all samples, validating the process of species identification. In groundwater samples, conditions being reducing, the As3+ species is supposed to be predominant. These findings can guide future bioremediation strategies to be effectively designed, as per the distribution of Arsenic species in the surface water.
Keywords: As3+; As5+; FIAS; Furnace; Environmental Samples; Arsenic Speciation
Highlights
a) Standardization of Arsenic speciation in synthetic samples using FIAS (Flame Ionisation Atomic Absorption Spectrometry) and Graphite Furnace methods.
b) Application of Arsenic speciation in environmental samples with total arsenic content.
c) Determination of predominant inorganic Arsenic species in surface water system.
Introduction
Arsenic is a ubiquitous metalloid found in lithosphere, hydrosphere, atmosphere and biosphere [1]. Natural minerals are the key source of arsenic. The soil arsenic concentration ranges from 0.1 to 40 mg/kg around the world, while, in water, it ranges from <0.05 to 5000 μg/l [2,3]. Arsenic and its compounds are highly toxic. Studies have shown that consumption of water with high arsenic content can lead to arsenical skin lesions [4]. According to the World Health Organization (WHO), the recommended arsenic concentration in potable water is 10 μg/l. Prolonged exposure to arsenic can lead to skin cancer, neurological disorders, lung cancer, liver cancer and adverse obstetric effects [5-9]. Groundwater arsenic contamination has become an issue of great concern across the world. A number of countries have been affected by high arsenic concentration in groundwater, when it is a source of drinking water. Of them, Bangladesh and India (West Bengal) have been affected the worst [4,10,11]. The elevated presence of arsenic in the groundwater of the Bengal Delta Plain (BDP) has been termed as “the worst mass poisoning in human history” [12]. Other affected countries are Vietnam, Thailand, Cambodia, Taiwan, Mongolia, China (Xinjiang region), Chile, Argentina, Bolivia, Brazil, Mexico, Ghana, Germany, Greece, Spain, Canada and the United States [13]. In West Bengal, six districts are adversely affected by arsenic contamination in groundwater: North 24 Parganas, South 24 Parganas, Nadia, Burdwan, Murshidabad and Malda. The total affected area is around 34,000 km2 with a population of about 30 million (44.4% of the total population of West Bengal). About 800,000 people in this region drink arsenic contaminated water and about 175,000 people are suffering from arsenic related diseases [10]. Other Indian states such as Bihar, Jharkhand, Madhya Pradesh and Assam are also affected by the issue. Out of 64 districts in Bangladesh, 51 have been detected with arsenic contamination. The total area of these 51 districts is 121,145 km2 and population of about 113 million (87% of the total population of Bangladesh) [5]. Excessive use of hand tube wells for drinking water and other purposes has caused the major outbreak of arsenic contamination in these regions. The biogeochemical cycle of arsenic involves a number of physicochemical processes, such as redox reactions, adsorption, desorption, ion exchange, solid phase precipitation and dissolution. Microbiological processes play a crucial role in these processes [14]. Several factors like redox potential, pH, organic carbon and chemical speciation play important roles in these processes [14,15]. Arsenic occurs in four oxidation states: elemental arsenic (As0), arsenite (As3+), arsenate (As5+) and arsenide (As3-). Among these species, As3+ and As5+ are the most common ones found in aquatic environment [16]. Distribution and mobility of these arsenic species depend upon local physicochemical conditions as well as biological processes. The pKa values of arsenic acid (H3AsO4; contains arsenic in the form of As5+) are – pKa1 = 2.19, pKa2 = 6.94 and pKa3 = 11.5. Therefore, at low pH (i.e., below 6.9) and oxidizing condition, H2AsO4 - is the predominant form, whereas, at higher pH levels, HAsO4 2- is the predominant form. Arsenate, being negatively charged, gets adsorbed easily on the oxidized minerals [17]. The lowest pKa value for As3+ is 9.22. In most natural water with pH below 9.2 as well as reducing condition, As(OH)3 is the predominant form. Solubility of arsenic depends upon its speciation [18]. Elemental arsenic is not very common in the environment, and organic forms of arsenic are found only in extremely reducing conditions (within live biomass) [19].
Objectives of This Study
This study aims to identify the method of selective determination of As3+and the total Arsenic in a solution where Arsenic exists in both trivalent and pentavalent state, by combining two methods:
a) Hydride generation through Flame – FIAS technique. (PinAAcle 900H Atomic Absorption Spectrometer, Perkin Elmer)
b) Furnace method (PinAAcle 900H Atomic Absorption Spectrometer, Perkin Elmer)
Application of the method in determination of As species in environmental samples (river water samples).
Subtracting the result of trivalent arsenic from total Arsenic, pentavalent Arsenic concentration of the solution can be measured. Presence of other forms of Arsenic is assumed to be negligible.
Methodology and Methodology
Basic Reagent Preparation
a) As3+ standard 50 μg/l : From stock 1000mg/l NIST As3+ soln. 0.1 ml was added to 100 ml volumetric flask and volume made up to 100 ml with milli Q water resulting 1000 μg/L of As3+ solution. From it 5 ml was added to 100 ml volumetric flask yield to 50 μg/l of As3+ soln. by volume make up with milli Q water.
b) As5+ standard 50μg/l : From stock 1000mg/l NIST As5+ soln. 0.1 ml was added to 100 ml volumetric flask and volume made up to 100 ml with milli Q water resulting 1000 μg/L of As5+ solution. From it 5 ml was added to 100 ml volumetric flask yield to 50 μg/l of As3+ soln. by volume make up with milli Q water.
c) Calibration standard: from 1000 μg/L of As3+ solution 4,10,20,30,40 μg/L of calibration standards were prepared.
d) Tris - Buffer (2.5 M, pH 6.2) : 75.69 gm Tris Base was dissolved in 130 ml of milli Q water. Then Conc. HCl was added continuously by checking the pH in pH meter and final pH was maintained at 6.2. Then volume was made up to 250 ml with milli Q water in a 250 ml volumetric flask.
Specific Reagent for Flame-FIAS Method
Sodium Borohydride (Reductant): 6 gm of Sodium Borohydride was dissolved in 1000 ml vol. flask with 0.6 gm of NaOH with milli Q water
Carrier Acid (3% HCl): 30 ml Conc. HCl is dissolved in 1000 ml milli Q water in 1 L volumetric flask.
Specific Reagent For Furnace Method
Chemical modifier :1%(10g/L) Pd stock solution & 1%(10g/L) Mg stock solution were prepared. 3ml of Pd stock & 0.3 ml of Mg stock solution is added to 10 ml of MQ water.
Collection of Samples:
Sampling Sites: The sampling sites were selected based on the As contamination results obtained from routine monitoring procedure undertaken by the West Bengal Pollution Control Board. Typically, two surface water streams in the lower Gangetic delta exhibited high Arsenic contamination, namely Churni and Jalangi. Three sampling points were identified in River Churni and one point from River Jalangi. Both rivers are trans-boundary and are tributaries of the River Ganges. Sampling points on River Churni are located at Majdia (23° 23’ 60’’ N, 88° 42’ 0’’ E), Shantipur- Ranaghat (23° 10’ 12’’ N, 88° 32’ 60’’ E) and Mathabhanga Govindapur (23° 23’ 56.4’’ N, 89° 43’ 15.6’’ E) of the Nadia district. Sampling points on River Jalangi (23° 49��� 12’’ N, 88° 28’ 19.2’’ E) are located at Krishnanagar of Nadia District.
Sampling Procedure: The water samples were collected from the sampling points in sterile containers and were transported to laboratory on ice for further analysis. The samples were immediately transported to the laboratory in ice cold condition in heat insulated container. The samples were refrigerated at 4⁰C, if not processed immediately.
Experimental Procedure
1st Experiment
Two sets of mixed solutions were prepared according to the Table 1 – named as Set A (A1-A8) & Table 2 for Set B (B1-B8). 1 ml Tris buffer was added to each solution of Set A. The following experimental solutions are prepared from 50 μg/l of both As3+and As5+stock solutions.
2nd Experiment
For checking interference, two sets of mixed solutions were prepared according to the Table 3 – named as Set C (C1-C7) & Set D (D1-D7). 1 ml Tris buffer was added to each solution of Set C. The concentrations of Set A, B, C & D solutions were measured by Flame FIAS method against the calibration curve.
3rd Experiment
Two set of samples were prepared according to Table 4 & named as Set E (1-8) & F (1-8).Undigested synthetic samples were used in Set E. And in Set F, synthetic samples were digested with Conc. HNO3 by Microwave Digestion System (Anton PAAR). (Digestion Method: 15 ml sample + 0.75 ml conc. HNO3. Run Program- USER 004M) Then Set E & F, are analyzed by furnace method.
4th Experiment Applied on Environmental Samples
Eight environmental samples were taken for Arsenic speciation study. 50 ml aliquot of each sample was taken in 50 ml test tube. The pH of each sample was checked to neutral. Then samples were analyzed by Flame FIAS method to get As3+ concentration.
The same 8 environmental samples were subject to digestion. 15 ml of sample was digested in MDS with 0.75 ml conc. HNO3. Then samples were analyzed by Furnace method to get total Arsenic concentration. Subtracting As3+concentration from total Arsenic concentration, As5+ concentrations were obtained.
Results and Discussion
Several mixtures (As3+ + As5+) were analyzed both in the presence and absence of buffer. Reported values of As3+in both set A2 & B2 are 4.632μg/l & 4.804μg/l, respectively. However, the mixture (As3+/As5+ in sets A1 & B1) actually contains 0 μg/l As3+ & 30 μg/l As5+. Hence, it may be assumed that a positive interference (artifact) may be due to reduction of any As5+present or any impurities.
Whether the reported value of As3+in sets A2 and B2 (at actual value of 0 μg/l of As3+ in mixed solution As3+/As5+) depends on As5+ concentration or not, can be ascertained by analyzing different solutions with varying concentrations of As5+ against As3+ calibration curve in Flame-FIAS method. Blank concentrations in the presence and absence of buffer, i.e for A1 & B1 are reported as 0.006 μg/l & 0.096μg/l respectively
It can be presumed that a value due interference (obtained in case of seta A1 and B1) coming from As5+NIST Standard in mixed solutions of As3+/As5+are appeared. To check the interference, the solutions of As5+ of different concentrations are may be measured against As3+ standard curve by Flame FIAS method.
From the above experimental data (Table 5) it was observed that the interference value due to As5+ was not increasing proportionately & also reported below our lowest calibration standard value. Hence, the quantification of interference value due to As5+ is not possible at pH 6-7.
Chemistry Behind This Phenomenon
In the hydride generation method through Flame-FIAS, the total As (As3+ and As5+) was reduced to As3+ (followed by simultaneous conversion to arsine, AsH3 gas) using a reducing agent (Sodium borohydride). If the pH was maintained at near neutral range (6- 7), the reduction (As5+ to As3+) did not occur, and only the portion of the As present in trivalent form was selectively converted to AsH3. Using TRIS buffer, the pH of the solution was maintained at 6.2, where As5+ was expected not to get reduced to As3+, and only the fraction of As present in trivalent form gets converted to AsH3, As3+ (and not total As) was selectively determined by Flame – FIAS method. In this study, several mixtures (As3+ + As5+) are analysed both in the presence and absence of buffer to understand the effect of pH on the reduction of As5+ to As3+.
Chemical Reaction behind this conversion may be:
It was observed (as indicated in Figure 1) that on increasing the concentration of As3+ in the mixtures, the same was reflected in the spectrometric data, for both the sets (A & B), i.e. As3+ fraction in the solution gets converted to AsH3. It was also observed (as indicated in Figure 2) increasing pH (in the experimental range from pH 5 to pH 7) the interference of As 5+ decreased in arsenic solution in Flame FIAS method. From the Table 6, concentration of total Arsenic (given 30 μg/l) was varying from 23.25 to 24.6 μg/l in the undigested samples (set E) even at pH=2, due to unknown chemical interferences. But in case of digested samples at same pH (Set F) the concentration of Total As was around 30μg/l. In case of environmental samples the presence of total Arsenic went above the range of WHO standards (=10μg/l) but the more toxic species of Arsenic (i.e., As3+) varied from 1.66 to 3.94 μg/l following natural chemical phenomenon (Tables 7 & 8).
Therefore, we can apply this method for speciation of Arsenic in this kind of environmental samples.
Conclusion
We conclude that the FLAME-FIAS method can be used to determine As3+ in the mixed solution of As3+/As5+ at neutral pH as Arsenic speciation technique by plotting As3+ NIST standard calibration curve. An interfering value, due to transformation of As5+ to As3+ to some extent, is reflecting in the above experiment which cannot be nullified in this experimental condition. Additionally, in the case of the Furnace method, undigested synthetic samples have a certain amount of interference in comparison to the digested ones. Through application of this speciation study in environmental samples following standardized protocol, the concentration of As3+ is found to be low. Therefore, future remediation processes in this region should be planned according to the distribution of inorganic species reported here.
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THE MOST IMPORTANT VITAMIN IN YOUR BODY
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THE MOST IMPORTANT VITAMIN IN YOUR BODY
Vitamins and minerals are considered essential nutrients because acting in concert, they perform hundreds of roles in the body.
They help shore up bones, heal wounds, and bolster your immune system. They also convert food into energy, and repair cellular damage.
What is the most important vitamin for your body?
Magnesium – This mineral plays an important role in muscle contractions. …
Calcium – This mineral is very essential for bone and teeth health. …
Vitamin C – This water-soluble vitamin plays important roles in immune system function. …
Vitamin B-12 – This is one of the most important essential vitamins.
VITAMIN A. GOOD FOR: Healthy eyes and general growth and development, including healthy teeth and skin. …
B VITAMINS. GOOD FOR: Energy production, immune function and iron absorption. …
VITAMIN C. …
VITAMIN D. …
VITAMIN E. …
VITAMIN K. …
FOLIC ACID. …
CALCIUM.
Is it important to take vitamins?
Most people do not need to take vitamin supplements and can get all the vitamins and minerals they need by eating a healthy, balanced diet.
Vitamins and minerals, such as iron, calcium and vitamin C, are essential nutrients that your body needs in small amounts to work properly.
What vitamins do we need daily?
According to Nutritionists, These Are some of Ingredients Your Multivitamin Should Have
Vitamin D. Vitamin D helps our bodies absorb calcium, which is important for bone health. …
Magnesium. Magnesium is an essential nutrient, which means that we must get it from food or supplements. …
Calcium. …
Zinc. …
Iron. …
Folate. …
Vitamin B-12.
What vitamins can be made by the human body?
Vitamins-what vitamins the body produces. The human body can produce vitamin D and vitamin K. Vitamin K is a vitamin that acts in the liver, affecting the manufacture of the substances that makes the blood.
Does multivitamin increase weight?
By taking multivitamins, there’s an increased chance that your body will have all the nutrients it needs to function properly.
This may impact upon your weight because of its effect on the metabolism, which is assisted by a wide variety of nutrients.
What happens when you start taking vitamins?
You might experience transient digestive upset when you first start out. It’s very common to experience this side effect when you start a supplement regime and typically it happens when you take your vitamins on an empty stomach.
Does multivitamin have side effects?
When taken as directed, multivitamins are not expected to cause serious side effects. Common side effects may include: upset stomach; headache among others.
Can I take vitamins at night?
Medics suggests taking your dietary supplements at night isn’t advisable. “Digestion slows down during sleep, so taking your nutrient supplement late at night would not be associated with an efficient absorption.”
How can a skinny person gain weight?
Don’t drink water before meals. This can fill your stomach and make it harder to get in enough calories.
Eat more often. …
Drink milk. …
Try weight gainer shakes. …
Use bigger plates. …
Add cream to your coffee. …
Take creatine. …
Get quality sleep.
What happens if you take vitamins everyday?
A recent study of 14,000 men aged 50 and older found that daily multivitamin supplementation “significantly reduced the risk of total cancer.”
Boosts immunity: Vitamin C is a strong antioxidant known for strengthening the immune system. Vitamins D and E boost immunity, too.
What does multivitamin do to your body?
The vitamins and minerals in your daily multivitamin can also significantly reduce levels of stress and anxiety.
The body uses B vitamins to convert food into energy, keep the nervous system functioning properly, and to produce stress hormones.
Taking multivitamins daily can replenish your body’s supply.
What vitamins actually work?
A team of researchers in Canada found that common supplements such as multivitamins, vitamin D, calcium and vitamin C provide no protection against heart disease, heart attack, stroke or premature death.
Folic acid and B-vitamins were associated with a reduced risk of heart disease and stroke.
Does multivitamin make you sleepy?
After controlling for age, sex and other variables, the scientists found a slightly higher rate of poor or interrupted sleep in people taking multivitamins.
Do multivitamins actually work?
If you take a multivitamin, it’s probably because you want to do everything you can to protect your health.
But there is still limited evidence that a daily cocktail of essential vitamins and minerals actually delivers what you expect.
Most studies find no benefit from multivitamins in protecting the brain or heart.
Which fruits increase weight?
Fruits that help in gaining weight naturally
Mango. One of the most delicious fruits, mango is a rich source of several nutrients such as copper, vitamin B, and vitamin A and E. …
Bananas. If you want perfect muscles, then bananas happen to be the best choice. …
Coconut. …
Dried fruits. …
Avocados This exotic fruit is great for someone who wants to gain weight.
What foods help you gain weight?
Homemade protein smoothies. Drinking homemade protein smoothies can be a highly nutritious and quick way to gain weight. …
Milk. Milk has been used as a weight gainer or muscle builder for decades (1). …
Rice. …
Nuts and nut butters. …
Red meats. …
Potatoes and starches. …
Salmon and oily fish. …
Protein supplements.
How long do vitamins stay in your body?
Vitamins Hang Out in Water and Fat
They wait around in your body fat until your body needs them. Fat-soluble vitamins are happy to stay stored in your body for awhile, some stay for a few days, some for up to 6 months!
Is multivitamin good for skin?
Vitamin D is one of the best vitamins for your skin, along with vitamins C, E, and K. Making sure you get enough vitamins can keep your skin looking healthy and youthful. This could translate to a reduction in: dark spots.
Are vitamins a waste of money?
Most vitamins may be a waste of money, but study finds two exceptions. The majority of vitamins and other nutritional supplements don’t increase lifespan or protect one’s heart health, a huge analysis out of Johns Hopkins University has found.
What is the No 1 food supplement in the world?
USANA
2, 2019 /PRNewswire/ — USANA, a leader in the health and wellness industry, was named the number one vitamin and dietary supplement brand in Philippines*.
This claim was granted by Euromonitor, the world’s leading provider for global business intelligence, market analysis and consumer insights.
Can I take all my vitamins at once?
Combining supplements will not normally interfere with the way they work and in some cases may be beneficial, for example vitamin C helps iron absorption.
However, certain supplements may interact with each other.
Is Centrum a good vitamin?
Centrum One A Day Men’s Health Formula
One tablet of this multivitamin includes all essential nutrients for men, except iron.
However, it provides less than 100% of the RDI for several important nutrients, including thiamine, niacin, biotin, calcium, magnesium and vitamins A, E and K.
Which fruit is good for skin glow?
The best sources are blackcurrants, blueberries, broccoli, guava, kiwi fruits, oranges, papaya, strawberries and sweet potatoes.
Vitamin C is needed to produce collagen that strengthens the capillaries that supply the skin. Read more about vital vitamins and the health benefits of oranges.
Which fruit is high in sugar?
Watermelon
A medium wedge of this summer treat has 17 grams of sugar. As its name suggests, it’s loaded with water, and it has special minerals called electrolytes that are just what your body needs to recharge after some time in the sun. Just keep it to a slice or two.
Does banana make you fat?
Let’s just make it clear here itself that bananas in themselves are not fattening. In fact, banana can help in losing weight as they have high fibre content and also have a good number of calories.
Even during weight loss, your body needs a certain number of calories which should not come from unhealthy foods.
Does milk make you gain weight?
The creation of low fat and no fat dairy products has further added to the belief that dairy foods are fattening.
But research shows that having enough milk, yoghurt and cheese every day, as part of a healthy diet, is not linked to weight gain.
How can a woman gain weight in one week?
Consumption of energy-rich foods: Make sure to eat, energy-dense foods like nuts including almonds, walnuts, peanuts, dried fruits including raisins or prunes, dark chocolate, high-fat dairy foods like condensed milk, full-fat cream, cheese, milk, veggies like potatoes and yams, etc.
What is the most toxic of all vitamins?
Owing to their ability to accumulate in the body, fat-soluble vitamins have a higher potential for toxicity than do water-soluble vitamins.
Iron-containing vitamins are the most toxic, especially in pediatric acute ingestions
Which vitamin makes skin white?
Vitamin C helps to lighten and brighten skin naturally to fight dark spots, while promoting collagen production and defending against free radical damage.
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Biomed Grid | Neurotoxin and Alpha-Neurotoxin Time-Resolved Absorption and Resonance FT-IR and Raman Bio spectroscopy and Density Functional Theory (DFT) Investigation of Vibrionic-Mode Coupling Structure in Vibrational Spectra Analysis
Abstract
α-Neurotoxins are a group of neurotoxic peptides found in the venom of snakes in the families Elapidae and Hydrophiidae. They can cause paralysis, respiratory failure, and death. Members of the three-finger toxin protein family, they are antagonists of post-synaptic nicotinic acetylcholine receptors (nAChRs) in the neuromuscular synapse that bind competitively and irreversibly, preventing synaptic acetylcholine (ACh) from opening the ion channel. Over 100 α-neurotoxins have been identified and sequenced. Parameters such as FT-IR and Raman vibrational wavelengths and intensities for single crystal Neurotoxin and Alpha-Neurotoxin are calculated using density functional theory and were compared with empirical results.
The investigation about vibrational spectrum of cycle dimers in crystal with carboxyl groups from each molecule of acid was shown that it leads to create Hydrogen bounds for adjacent molecules. The current study aimed to investigate the possibility of simulating the empirical values. Analysis of vibrational spectrum of Alpha-Neurotoxin is performed based on theoretical simulation and FT- IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of F/6-31G*, HF/6- 31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6-31G, BLYP/6-31++G**, B3LYP/6-31G and B3LYP6-31-HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated. The obtained values confirm high accuracy and validity of results obtained from calculations [1-42] (Figure 1).
Figure 1: Molecular structure of Neurotoxin (left) and Alpha–Neurotoxin (right).
Keywords:Vibrionic Structure; Vibrational Spectra Analysis; Density Functional Theory (DFT); Alpha-Neurotoxin; non-Focal Functions of Becke; Correlation Functions of Lee-Yang-Parr; Time-Resolved Absorption and Resonance; FT-IR and Raman Bio spectroscopy
Introduction
α-Neurotoxins are a group of neurotoxic peptides found in the venom of snakes in the families Elapidae and Hydrophiidae. They can cause paralysis, respiratory failure, and death. Members of the three-finger toxin protein family, they are antagonists of post-synaptic nicotinic acetylcholine receptors (nAChRs) in the neuromuscular synapse that bind competitively and irreversibly, preventing synaptic acetylcholine (ACh) from opening the ion channel. Over 100 α- neurotoxins have been identified and sequenced.
Density Functional Theory (DFT) is one of the most powerful calculation methods for electronic structures [5-7]. Numerous results have been previously studied and indicate successful use of these methods [8-10]. The theory is one of the most appropriate methods for simulating the vibrational wavenumbers, molecular structure as well as total energy. It may be useful to initially consider the calculated results by density functional theory using F/6-31G*, HF/6-31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6- 31G, BLYP/6-31++G**, B3LYP/6-31G and B3LYP6-31- HEG** approach [11-16]. It should be noted that calculations are performed by considering one degree of quantum interference as well as polarization effects of 2d orbitals in interaction [17-320].
Details of Calculations
All calculations of molecular orbital in the base of ab are performed by Gaussian 09. In calculation process, the structure of Alpha-Neurotoxin molecule (Figure 2) is optimized and FT- IR and Raman wavenumbers are calculated using F/6-31G*, HF/6- 31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6-31G, BLYP/6- 31++G**, B3LYP/6-31G and B3LYP6-31-HEG** base. All optimized structures are adjusted with minimum energy. Harmonic vibrational wavenumbers are calculated using second degree of derivation to adjust convergence on potential surface as good as possible and to evaluate vibrational energies at zero point. In optimized structures considered in the current study, virtual frequency modes are not observed which indicates that the minimum potential energy surface is correctly chosen. The optimized geometry is calculated by minimizing the energy relative to all geometrical quantities without forcing any constraint on molecular symmetry. Calculations were performed by Gaussian 09.
Figure 2:Different sections of the Neurotoxin (upper) and Alpha– Neurotoxin (lower) [43–93].
The current calculation is aimed to maximize structural optimization using density functional theory. The calculations of density functional theory are performed by F/6-31G*, HF/6- 31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6-31G, BLYP/6- 31++G**, B3LYP/6-31G and B3LYP6-31-HEG** function in which non-focal functions of Becke and correlation functions of Lee-Yang- Parr beyond the Franck-Condon approximation are used. After completion of optimization process, the second order derivation of energy is calculated as a function of core coordination and is investigated to evaluate whether the structure is accurately minimized. Vibrational frequencies used to simulate spectrums presented in the current study are derived from these second order derivatives. All calculations are performed for room temperature of 316 (K).
Vibration Analysis
Analysis of vibrational spectrum of Alpha-Neurotoxin is performed based on theoretical simulation and FT-IR empirical spectrum and Raman empirical spectrum using density functional theory in levels of F/6-31G*, HF/6-31++G**, MP2/6-31G, MP2/6- 31++G**, BLYP/6-31G, BLYP/6-31++G**, B3LYP/6-31G and B3LYP6-31-HEG**. Vibration modes of methylene, carboxyl acid and phenyl cycle are separately investigated. C-H stretching vibrations in single replacement of benzene cycles are usually seen in band range of 3250-3650 cm-1. Weak Raman bands are at 3191 cm-1 and 3207 cm-1. C-C stretching mode is a strong Raman mode at 1211 cm-1. Raman weak band is seen at 1687 cm-1 too. Bending mode of C-H is emerged as a weak mode at 1429 cm-1 and 1205 cm-1 and a strong band at 1289 cm-1 in Raman spectrum. Raman is considerably active in the range of 1250-1650 cm-1 which 1199 cm-1 indicates this issue.
C-H skew-symmetric stretching mode of methylene group is expected at 3189 cm-1 and its symmetric mode is expected at 3000 cm-1. Skew-symmetric stretching mode of CH4 in Alpha- Neurotoxin has a mode in mid-range of Raman spectrum at 3250- 3650 cm-1. When this mode is symmetric, it is at 3099 cm-1 and is sharp. The calculated wavenumbers of higher modes are at 3073 cm-1 and 3096 cm-1 for symmetric and skew-symmetric stretching mode of methylene, respectively.
Scissoring vibrations of CH4 are usually seen at the range of 1530-1590 cm-1 which often includes mid-range bands. Weak bands at 1550 cm-1 are scissoring modes of CH4 in Raman spectrum. Moving vibrations of methylene are usually seen at 1479 cm -1. For the investigated chemical in the current study, these vibrations are at 1349 cm-1 were calculated using density functional theory. Twisting and rocking vibrations of CH4 are seen in Raman spectrum at 925 cm-1 and 1191 cm-1, respectively, which are in good accordance with the results at 907 cm-1 and 1167 cm- 1, respectively. In a non-ionized carboxyl group (COOH), stretching vibrations of carbonyl [C=O] are mainly observed at the range of 1850-1898 cm-1. If dimer is considered as an intact constituent, two stretching vibrations of carbonyl for symmetric stretching are at 1750-1795 cm-1 in Raman spectrum. In the current paper, stretching vibration of carbonyl mode is at 1799 cm-1 which is a mid-range value.
Stretching and bending bands of hydroxyl can be identified by width and band intensity which in turn is dependent on bond length of Hydrogen. In dimer form of Hydrogen bond, stretching band of O-H is of a strong Raman peak at 1377 cm-1 which is due to in-plain metamorphosis mode. Out-of-plain mode of O-H group is a very strong mode of peak at 1056 cm-1 of Raman spectrum. The stretching mode of C-O (H) emerges as a mid-band of Raman spectrum at 1263 cm-1. Lattice vibrations are usually seen at the range of 0-850 cm-1. These modes are induced by rotary and transferring vibrations of molecules and vibrations and are including Hydrogen bond. Bands with low wavenumbers of Hydrogen bond vibrations in FT-IR and Raman spectrum (Figure 3) are frequently weak, width and unsymmetrical. Rotary lattice vibrations are frequently stronger than transferring ones. Intramolecular vibrations with low wavenumbers involving two-bands O-H …O dimer at 99 cm-1, 199 cm-1 and 269 cm-1 are attributed to a rotary moving of two molecules involving in-plain rotation of molecules against each other.
Figure 3:3D Simulation of (a) FT–IR spectrum and (b) Raman spectrum of Alpha–Neurotoxin.
Conclusion and Summary
Calculations of density functional theory using F/6-31G*, HF/6- 31++G**, MP2/6-31G, MP2/6-31++G**, BLYP/6-31G, BLYP/6- 31++G**, B3LYP/6-31G and B3LYP6-31-HEG** levels were used to obtain vibrational wavenumbers and intensities in single crystal of Alpha- Neurotoxin. Investigation and consideration of vibrational spectrum confirm the formation of dimer cycles in the investigated crystal with carboxyl groups from each Hydrogen molecule of acid protected from adjacent molecules. The calculated vibrational spectrum which obtains from calculations of density functional theory is in good accordance with recorded empirical values which indicates successful simulation of the problem. The obtained results indicate that the results obtained from theoretical calculations are valid through comparing with empirical recorded results.
Acknowledgements
Authors are supported by an American International Standards Institute (AISI) Future Fellowship Grant FT1201009373493. We acknowledge Ms. Isabelle Villena for instrumental support and Dr. Michael N. Cocchi for constructing graphical abstract figure. We gratefully acknowledge Prof. Dr. Christopher Brown for proofreading the manuscript.
Read More About this Article:https://biomedgrid.com/fulltext/volume3/neurotoxin-and-alpha-neurotoxin-time-resolved-absorption-and-resonance-ft-ir.000738.php
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There’s a lot of confusion and misdirection in the area of diet and aging, so let’s see if we can get some of it straightened out.
mTOR
mTOR is the mammalian target of rapamycin, a molecular mechanism that integrates growth and energy signals.[1] When mTOR is activated by nutrients, it signals the cell to grow.
mTOR is likely very important in promoting aging.
We know this because rapamycin, a drug that extends lifespan in lab animals, inhibits mTOR.[2] The basic idea is that mTOR signaling is vitally important in the growth of an organism, but that its activation after maturity results in aging.
Nutrients activate mTOR. Hence the power of calorie restriction to prolong lifespan: fewer nutrients, less mTOR activation, longer life.
Other lifespan-promoting agents also deactivate mTOR. Metformin, for example.[3] Iron chelators deactivate mTOR.[4] (And of interest, rapamycin interferes with iron metabolism.[5])
What sort of nutrients activate mTOR, and are they equally potent in activation?
It’s common to read that amino acids (from protein) activate mTOR, and indeed they do, but this is a very incomplete picture.[6]
Hence the obsessive idea in some quarters that dietary protein promotes aging is, if not entirely wrong, incomplete and misleading.
One reason the picture is misleading is because mTOR is intimately linked to insulin, the hormone whose primary purpose is to regulate glucose metabolism. See the illustration below, showing the linkage. Note that glucose also activates mTOR.[7]
Insulin activation is linked to mTOR activation. And what activates insulin the most? Carbohydrates.
IGF-1 signaling is also implicated in aging. Insulin and IGF-1 levels are highly correlated.[8]
Carbohydrates increase the risk of breast cancer recurrence 5-fold in IGF-1 positive cancer by increasing IGF-1 activity.[9]
Fasting
Intermittent fasting promotes longer lifespan.[10] Fasting appears to have all of the benefits but little of the downsides of calorie restriction.
Fasting activates AMPK, which inhibits mTOR. Note that other antiaging interventions like rapamycin and metformin also activate AMPK.
But, what aspect of fasting activates AMPK? Is it absence of food altogether, or absence of a particular macronutrient?
Carbohydrate restriction regulates the adaptive response to fasting.[11]
Human subjects either fasted for 3.5 days, or fasted and got a lipid infusion, and “Changes in plasma glucose, free fatty acids, ketone bodies, insulin, and epinephrine concentrations during fasting were the same in both the control and lipid studies.”
“These results demonstrate that restriction of dietary carbohydrate, not the general absence of energy intake itself, is responsible for initiating the metabolic response to short-term fasting.”
That’s not to say that protein has no involvement, but it does seem to confirm that the widely circulated pronouncements of certain scientists that protein promotes aging is badly misleading.
One reason that protein is likely to be much less of a concern than carbohydrates for aging is that the ketogenic diet, by definition very low in carbohydrates, extends lifespan.[12]
The ketogenic diet also inhibits mTOR and increases AMPK.[13] This is despite the fact that a ketogenic diet normally contains a full complement of protein, perhaps 10 to 15% of calories, and sometimes more.
Glucose and lifespan
There’s an abundance of evidence, all but ignored, that dietary glucose promotes aging.
Glucose triggers apoptosis in yeast chronological aging.[14]
Glucose restriction extends C. elegans life span by inducing mitochondrial respiration and increasing oxidative stress.[15]
Mice taking the anti-diabetic drug acarbose, which inhibits the absorption of carbohydrates, lived longer, males by 22%.[16]
Humans who took acarbose had a 50% reduction in cardiovascular risk.[17]
These results above are for dietary glucose. Carbohydrates are of course long chains of glucose, which when broken down become glucose in the body. If a person has the least bit of insulin resistance, and often even if they don’t, blood glucose rises.
Then there’s metformin which, next to rapamycin, is considered the best shot at a bona fide life extension drug.[18]
And what does metformin do? It lowers blood glucose and insulin via multiple mechanisms.
A drug that lowers glucose and insulin extends lifespan, showing the critical importance of these two molecules for aging and lifespan.
The OTC supplement glucosamine also extends lifespan, by interfering with glucose metabolism.[19]
Calorie and protein restriction
Some have thought that the effects of calorie restriction may be due to restriction of protein. One piece of evidence for that is that restriction of the single amino acid methionine extends lifespan, and seems to mimic calorie restriction.[20] However, methionine restriction isn’t the same as restricting all protein, and other mechanisms may account for it.
Calorie restriction improves glucose metabolism and lowers insulin levels, but protein restriction does not.[21]
“The effect of dietary restriction on lifespan in rodents is explained by calories alone.”[22]
Valter Longo recommends a vegan diet
Valter Longo, who is perhaps the scientist best known to the public in the field of aging research, recommends a (nearly) vegan diet for longevity.[23]
“Eat mostly vegan, plus a little fish, limiting meals with fish to a maximum of two or three per week… keep protein intake low… Minimize saturated fats from animal and vegetable sources (meat, cheese) and sugar, and maximize good fats and complex carbs.”
Based on what I’ve written above, there doesn’t seem to be a lot of solid backing for Longo’s recommendations. (Other than no sugar.)
He says nothing about avoiding ultra-processed foods, the main dietary cause of disease and early death in the developed world. His low-protein strategy is based on weak epidemiology, and doesn’t take into account all of the evidence laid out above that carbohydrates and glucose have far more to do with aging than protein, which may not matter at all.
Chronic mTOR activation
Activation of mTOR is not a problem for aging, in my view. Chronic activation is.
As we age, we become more insulin resistant, leading to chronically high insulin levels, and chronically activated insulin receptors. As we saw, insulin is connected to mTOR. When insulin increases, mTOR is activated.
Insulin is not a problem. It’s a necessary hormone that is there to do a job. Likewise, mTOR is a necessary molecular mechanism. Chronically activated mTOR promotes aging.
In a glucose tolerance test, 75 grams of glucose (15 teaspoons, a large bolus) are given orally. In a normal person, blood glucose and insulin will return to normal within 2 hours.[24]
If someone were eating all the time, or had insulin resistance due to obesity or some other condition, then glucose and insulin will remain elevated constantly. mTOR would be activated chronically.
Conclusion
A large body of evidence shows that carbohydrates generally, and glucose specifically, are much more important to aging than protein.
A ketogenic diet, by definition low in carbohydrates, extends lifespan. But to my knowledge, no one has ever shown that a vegan diet extends lifespan.
Scientists involved in the study of aging are of course specialized, but there’s an unfortunate tendency for them to ignore diet, other than calorie restriction.
Furthermore, again to my knowledge, no one has ever extended the lifespan of a carnivore by calorie restriction. Only omnivores, eating high-carbohydrate diets, have had their lives extended by calorie restriction.
Vegetarians are not overrepresented among long-lived humans. But people with low insulin resistance – high insulin sensitivity, leading to less chronic activation of mTOR – are.[25]
Dietary carbohydrates promote aging, and protein does less so if at all.
But somehow scientists are not seeing this. Update: I meant to include the following, very interesting study: Effect of Dietary Macronutrient Composition on AMPK and SIRT1 Expression and Activity in Human Skeletal Muscle. ( Draznin, B., et al. “Effect of dietary macronutrient composition on AMPK and SIRT1 expression and activity in human skeletal muscle.” Hormone and Metabolic Research 44.09 (2012): 650-655.)
Calorie restriction activates AMPK, the cellular energy sensor which deactivates mTOR. CR also activates PGC1 alpha, which promotes mitochondrial biogenesis. Both are key factors in long life.
The study used human volunteers in 4 conditions: overfeeding or underfeeding, each with a high carb or low carb diet.
“Our data indicate that a relative deficiency in carbohydrate intake or, albeit less likely, a relative excess of fat intake even in the absence of caloric deprivation is sufficient to activate the AMPK-SIRT 1-PGC1α energy-sensing cellular network in human skeletal muscle. “
This indicates that at least part of the physiological response to calorie restriction comes from a decrease in carbohydrate.
In all dietary conditions, protein was 20% of calories, which shows that protein has no effect on these responses to calorie restriction. It’s all about carbohydrates.
[1] Laplante, Mathieu, and David M. Sabatini. “mTOR signaling in growth control and disease.” Cell 149.2 (2012): 274-293.
[2] Blagosklonny, Mikhail V. “Calorie restriction: decelerating mTOR-driven aging from cells to organisms (including humans).” Cell Cycle 9.4 (2010): 683-688.
[3] Sahra, Isaam Ben, et al. “Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.” Cancer research 71.13 (2011): 4366-4372.
[4] Ohyashiki, Junko H., et al. “The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1.” Cancer science100.5 (2009): 970-977.
[5] Maiorano, Annamaria, et al. “Sirolimus interferes with iron homeostasis in renal transplant recipients.” Transplantation82.7 (2006): 908-912.
[6] Tokunaga, Chiharu, Ken-ichi Yoshino, and Kazuyoshi Yonezawa. “mTOR integrates amino acid-and energy-sensing pathways.” Biochemical and biophysical research communications 313.2 (2004): 443-446.
[7] Lamming, Dudley W. “Diminished mTOR signaling: a common mode of action for endocrine longevity factors.” Springerplus3.1 (2014): 735.
[8] Nam, S. Y., et al. “Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone.” International journal of obesity 21.5 (1997): 355.
[9] Emond, Jennifer A., et al. “Risk of breast cancer recurrence associated with carbohydrate intake and tissue expression of IGFI receptor.” Cancer Epidemiology and Prevention Biomarkers 23.7 (2014): 1273-1279.
[10] Honjoh, Sakiko, et al. “Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegans.” Nature457.7230 (2009): 726.
[11] Klein, S. A. M. U. E. L., and ROBERT R. Wolfe. “Carbohydrate restriction regulates the adaptive response to fasting.” American Journal of Physiology-Endocrinology and Metabolism 262.5 (1992): E631-E636.
[12] Roberts, Megan N., et al. “A ketogenic diet extends longevity and healthspan in adult mice.” Cell metabolism 26.3 (2017): 539-546.
[13] McDaniel, Sharon S., et al. “The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway.” Epilepsia52.3 (2011): e7-e11.
[14] Ruckenstuhl, Christoph et al. “The sweet taste of death: glucose triggers apoptosis during yeast chronological aging.” Aging vol. 2,10 (2010): 643-9. doi:10.18632/aging.100223
[15] PMID: 17908557
[16] Harrison, David E., et al. “Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males.” Aging cell 13.2 (2014): 273-282.
[17] Chiasson, Jean-Louis, et al. “Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial.” Jama290.4 (2003): 486-494.
[18] Chiasson, Jean-Louis, et al. “Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial.” Jama290.4 (2003): 486-494.
[19] Weimer, Sandra et al. “D-Glucosamine supplementation extends life span of nematodes and of ageing mice.” Nature communications vol. 5 3563. 8 Apr. 2014, doi:10.1038/ncomms4563
[20] Richie Jr, John P., et al. “Methionine restriction increases blood glutathione and longevity in F344 rats.” The FASEB Journal 8.15 (1994): 1302-1307.
[21] Mitchell, Sharon E et al. “The effects of graded levels of calorie restriction: II. Impact of short term calorie and protein restriction on circulating hormone levels, glucose homeostasis and oxidative stress in male C57BL/6 mice.” Oncotarget vol. 6,27 (2015): 23213-37. doi:10.18632/oncotarget.4003
[22] Speakman, J. R., Sharon Elizabeth Mitchell, and M. Mazidi. “Calories or protein? The effect of dietary restriction on lifespan in rodents is explained by calories alone.” Experimental Gerontology 86 (2016): 28-38.
[23] https://valterlongo.com/daily-longevity-diet/
[24] Crofts, Catherine, et al. “Identifying hyperinsulinaemia in the absence of impaired glucose tolerance: An examination of the Kraft database.” Diabetes research and clinical practice 118 (2016): 50-57.
[25] Barbieri, Michelangela, et al. “Age‐related insulin resistance: is it an obligatory finding? The lesson from healthy centenarians.” Diabetes/metabolism research and reviews17.1 (2001): 19-26.
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50 Foods That Are Super Healthy
Foods That Are Super Healthy
It’s really hard to know which foods are super healthy. A vast number of foods are both tasty and healthy. By filling your plate with quality protein, vegetables, fruits, and other whole foods, you’ll have meals that are versatile, colorful and good for you.
Here are 50 incredibly super healthy foods. Almost all of them are surprisingly delicious.
1−6: Fruits and Berries — Foods That Are Super Healthy
Berries and fruits are among the world’s most popular foods.
These nutritious, sweet foods are very easy to incorporate into your daily routine diet because they require little to no preparation.
Apples
Apples are high in vitamin C, fiber and numerous antioxidants. If you find yourself hungry between meals then apples are perfect snacks for you.
2. Avocados
This fruit is different than most fruits because instead of carbs they are loaded with healthy fats. Avocados are tasty and creamy and also high in vitamin C, potassium and fiber.
3. Bananas
Bananas are full of potassium. They are also high in fiber and vitamin B-6, as well as portable and convenient.
4. Blueberries
Blueberries are among the most powerful sources of antioxidants in the world and one plus point they are really delicious.
5. Oranges
Who doesn’t know that oranges are packed with vitamin C? what’s more, they are high in antioxidants and fiber.
6. Strawberries
Strawberries are low in both calories and carbs but highly nutritious.
They are loaded with manganese, fiber and vitamin C and are arguably among the most delicious foods on the planet.
Other healthy fruits
Other healthy fruits and berries include raspberries, plums, pineapples, pears, kiwifruit, peaches, grapefruit, olives, grapes, melons, cherries, mango, and lemons.
7. Eggs
Eggs are full of nutrients. Previously people think they were high in cholesterol, but a new study shows that they are perfectly healthy and safe.
Read Also: 9 Foods That Promote Hair Growth
8−10: Meats — Foods That Are Super Healthy
Gently cooked, unprocessed meat is one of the most nutritious foods you can eat.
8. Lean beef
Lean beef is among the best sources of protein and loaded with bioavailable iron. If you are on a low carb diet, choosing the fatty cuts is fine.
9. Chicken breasts
Chicken breast is low in calories and fat but high in protein. It is a good source of many nutrients. If you are on a low carb diet, again choosing the fatty cuts is fine.
10. Lamb
Lambs meat tends to be high in omega-3 fatty acids because they are usually grass-fed.
Read Also: Try these six things to better sleep at night
11−16: Seeds and Nuts — Foods That Are Super Healthy
Despite being high in calories and fat, seeds and nuts may help you lose weight.
These foods are filling, crunchy and loaded with important nutrients that many people don’t get enough of, including vitamin E and magnesium. They are easy to add to your daily routine diet because they required almost no preparation.
11. Almonds
Almonds are a popular nut loaded with fiber, magnesium, antioxidants and vitamin E, studies show that almonds can help you improve metabolic health and lose weight.
12. Chia seeds
Chia seeds are high in nutrients. A single ounce packs a significant amount of magnesium, fiber, calcium, manganese and various other nutrients.
13. Coconuts
Coconuts are loaded with powerful fatty acids called medium-chain triglycerides and fiber.
14. Macadamia nuts
Macadamia nuts are full of taste. They are lower in omega-6 fatty acids than most other nuts and much higher in monounsaturated fats.
15. Walnuts
Walnuts are high in nutrients and packed with fiber and various minerals and vitamins.
16. Peanuts
Peanuts are very tasty and high in antioxidants and nutrients. According to different studies, peanuts can help you to lose weight.
Read Also: Best Foods that Prevent Cancer: Anti Cancer Foods
17−26: Vegetables — Foods That Are Super Healthy
Calorie to calorie, vegetables are the most concentrated sources of nutrients. There is a wide variety of vegetables available, and it is very good to eat many different types each day.
17. Asparagus
Asparagus is a very popular vegetable. It is low in both calories and carbs but packed with vitamin K.
18. Bell peppers
Bell peppers come in several colors, including green, yellow and red. They are sweet and crunchy, as well as a great source of vitamin C and antioxidants.
19. Brocolli
Brocolli tastes great both cooked and raw. It is an excellent source of vitamin C, vitamin K, and fiber and contains a decent amount of protein.
20. Carrots
Carrots are a famous root vegetable. They are packed with nutrients like vitamin K and fiber. Carrots are also very rich in carotene antioxidants which have decent benefits.
21. Cauliflower
Cauliflower is a cruciferous vegetable which tastes good on its own. It can be used in different dishes.
22. Cucumber
Cucumbers are one of the world’s most popular vegetables. They are very low in both calories and carbs, consisting mostly of water. They contain vitamin K in a very small amount.
23. Garlic
Garlic is very healthy. It contains organosulfur that helps to improve immune function.
24. Kale
Kale has become very popular because it is incredibly high in vitamin C, Vitamin K and fiber, and a number of other nutrients. If adds a satisfying crunch to salads.
25. Onions
Onions are very popular in many recipes because they have a very strong flavor. They contain a decent amount of bioactive compounds believed to have health benefits.
26. Tomatoes
Technically tomatoes are fruit but are usually categorized as a vegetable. They are very tasty and packed with nutrients like vitamin C and potassium.
More healthy vegetables
Most vegetables are very healthy. Other worth mentioning include zucchini, turnips, swiss chard, squash, radishes, mushrooms, lettuce, leeks, eggplant, celery, cabbage, brussels sprouts, and artichokes.
Read Also: High Blood Pressure at age 30 to 40 is dangerous for mental health
27−32: Fish and Seafood — Foods That Are Super Healthy
Fish and other seafood tend to be very nutritious and healthy. They are especially rich in iodine and omega-3 fatty acids. Studies show that people who eat seafood regularly have a lower risk of many illnesses, including depression, dementia, and heart disease.
27. Salmon
Salmon is a type of oily fish. It is good in taste and contains a high amount of nutrients, including omega-3 fatty acids and protein, and vitamin D as well.
28. Sardines
Sardines are oily, small fish that are among the most nutritious foods you can include in your routine diet.
29. Shellfish
When it comes to nutrient density, shellfish ranks similarly to organ meats. Edible shellfish include oysters, mollusks and clams.
30. Shrimp
Shrimp is a type of crustacean related to lobsters and crabs. It tends to be high in protein but low in calories and fat. It is also packed with various other nutrients, including vitamin B12 and selenium.
31. Trout
Similar to salmon, trout is a delicious freshwater fish.
32. Tuna
Tuna is very famous in western countries and tends to be low in calories and fat, while high in protein. It is a perfect food for people who need to add more protein to their diets.
Read Also: 5 Proven Health Benefits Of Dates
33−35: Grains — Foods That Are Super Healthy
Grains have gotten a bad rap in recent years but some types of grains are very healthy.
Just keep in mind that grains are relatively high in carbs, so if you are taking low-carb diet then not recommended.
33. Brown rice
Rice is the most popular cereal grains. Brown rice is very nutritious, with a decent amount of magnesium, vitamin B1 and fiber.
34. Oats
Oats are very healthy. They are packed with powerful fibers and nutrients, which provide numerous benefits.
35. Quinoa
Quinoa has become very popular in recent years among health-conscious individuals. It’s high in nutrients, such as magnesium and fiber.
Read Also: Benefits Of Rosemary For Hair Growth
36−37: Breads — Foods That Are Super Healthy
36. Ezekiel bread
Ezekiel bread is very healthy bread. It is made from sprouted, organic whole grains, as well as different legumes.
37. Homemade low carb bread
The best choice for bread may be which you can make at your home by yourself.
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38−40: Legumes — Foods That Are Super Healthy
Legumes contain antinutrients, which can interfere with the absorption of nutrients and digestion. They can be eliminated by proper preparation and soaking. Therefore, legumes are a very good source of plant-based proteins.
38. Green beans
Green beans are very popular in western countries. They are also called by string beans.
39. Kidney beans
Kidney beans are packed with minerals, vitamins, and fiber. Cook them very well because they are toxic when raw.
40. Lentils
Lentils are another popular legume.
They are among the best sources of plant-based protein and very high in fiber.
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41−43: Dairy — Foods That Are Super Healthy
Dairy products are packed with various important nutrients. Full-fat dairy seems to be the best because people who eat full-fat dairy have a lower risk of type 2 diabetes and obesity.
Dairy becomes more nutritious if it comes from grass-fed cows, as it is higher in some bioactive fatty acids like vitamin K2 and conjugated linoleic acid (CLA).
41. Cheese
Cheese is very nutritious, as a single slice of cheese may offer about the same amount of nutrients as 240 ml of milk.
42. Whole milk
Whole milk is very high in healthy fats, quality animal protein, minerals, and vitamins. It is one of the best sources of calcium.
43. Yogurt
Yogurt has the same health benefits as milk but yogurt has one extra benefit of friendly probiotic bacteria.
Read Also: what are the health benefits of papaya
44−46: Oils and Fats — Foods That Are Super Healthy
Many oils and fats are now marketed as health foods, including many sources of saturated fat that were before demonized.
44. Butter from grass-fed cows
Butter from grass-fed cows is packed in many nutrients, such as vitamin K2.
45. Coconut oil
Coconut oil contains high amounts of MCT. MCT helps to lose belly fat and aid Alzheimer’s disease.
46. Extra virgin olive oil
Extra virgin olive oil is very healthy vegetable oil. It is very high in antioxidants and contains heart-healthy monounsaturated fats.
Read Also: How To Remove Wrinkles Naturally
47−48: Tubers — Foods That Are Super Healthy
Tubers are the storage organs and contain a number of beneficial nutrients.
47. Potatoes
Potatoes contain a little bit of almost every nutrient you need, like vitamin C and packed with potassium.
48. Sweet potatoes
Sweet potatoes are very delicious starchy foods you can add in your routine diet. They are packed with antioxidants and other healthy nutrients. Sweet potato is a component rich in beta-carotene.
Read Also: REASONS! WHY GREEN TEA BENEFITS YOU PHYSICALLY AND MENTALLY
49. Apple cider vinegar
Apple cider vinegar is very popular in the health community. It can help lower blood pressure and cause weight loss. It is great to add flavor to meals or use as a salad dressing.
Read Also: Foods That promote hair growth – 5 best foods for your hair grow
50. Dark chocolate
Dark chocolate is packed with magnesium and antioxidants.
The bottom line
Whether you simply change up your meals or want to overhaul your diet, it is easy to add a number of these foods to your routine.
Many of the foods above not only loaded with antioxidants and vitamins but also make a great snack. Some of them even help to reduce weight loss.
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BEST AYURVEDIC PRODUCTS ONLINE - PRESERVA WELLNESS
Too much is pretty bad. That too when it comes to alcohol, then it is better to realise that alcohol has never been men’s or for that matter women’s friend! If you want to verify the stated fact, ask your liver about its views on alcohol. It would give out a loud cry and would let you know that alcohol hasn’t done any good to it but in fact has made the condition worse. Probably, your liver would find alcohol its worst enemy!
Well though there have been certain specified limits of alcohol which have been allowed by various countries but in reality even a glass of beer or wine a day can cause considerable damage to your liver!
Since liver is a tough organ, many toxins including those produced by consumption of alcohol can be flushed out from your body. This process helps in staying healthy till the time the amount of toxins does not exceed the limit of functioning of liver. Understand it this way. Suppose there is a stress that you are constantly suffering from. Your body will be able to handle it only to a certain extent. There would be a time at which your mental and physical strength will give up. Similarly your liver will give up when the levels of toxins cross its power of their neutralization and excretion.
When alcohol reaches your liver, a toxic enzyme called acetaldehyde is produced, which can damage your liver cells. The initial effects of alcohol on liver may not be paid attention to but long lasting effects cannot be ignored at all. The initial signs of damage due to alcohol can include pain in abdomen, nausea and vomiting, diarrhoea, and decreased appetite. The other effect which alcohol has on your liver is dehydration. Your liver needs water to do its job of flushing out toxins and when alcohol enters your body, it acts as a diuretic and thus dehydrates your body. This action of alcohol compels your liver to find water from other sources. And this is why you wake up with a severe headache in the morning after drinking a lot the previous night. When you indulge in drinking alcohol regularly, it gradually takes over the way through which by products are metabolised in your body. Regular and heavy drinking thus make your liver proceed towards alcohol liver disease. No doubt, alcohol is a ‘demon’s drink’.
The effects of alcohol on your liver vary according to your age, gender, mental health, drug use, and medical conditions. Excessive alcohol intake can affect the energy levels of your body. Alcohol replaces the food in your dietary intake and this can be responsible for weight loss or weight gain. In people who drink heavily, alcohol replaces nutrient-rich food which can cause deficiencies of various nutrients in your body.
Alcohol also interferes with normal digestion and absorption which makes the liver unable to absorb amino acids properly. Due to malabsorption of amino acids, many of the proteins which are required by the body cannot be produced in adequate quantity. Alcohol tends to interfere with the metabolism of fat in the body which leads to deposition of triglycerides in the liver cells and thus exacerbates the fatty liver condition. Alcohol does not let carbohydrate metabolism take place in an ideal way which can lead to development of insulin resistance in your body.
In alcoholics, the most serious conditions can develop due to deficiencies of vitamins and minerals. The most common vitamin deficiency in alcoholics occurs in form of vitamin B1 deficiency. Other deficiencies which can occur due to consumption of alcohol include those of folic acid, vitamins B, C, D, E, and, K, calcium, magnesium, phosphate, and zinc. In many cases, alcoholics may remain totally unaware about the nutritional deficiencies they are suffering from for long till the time an alarming sign occurs.
Once you are addicted to alcohol, quitting it completely can be quite difficult. There do exist several ways through which you can prevent the bad effects that alcohol causes on your liver. These steps include:
Gradually Taper the Intake of Alcohol: If you are told to stop drinking at all with immediate effect, you might be reluctant to it and may not be able to do it despite a genuine attempt. The easy way to get rid of alcohol in your routine is by bringing down the number glasses you take per day. If you drink daily, you may gradually adapt to drinking on alternate days and then to twice a week followed by once a week. The drinks would finally become occasional and can also completely get out of your life. You may keep the process of quitting slow but it needs to be steady.
Focus on Minimizing other Bad Habits Too: If you also smoke, try to taper that too. Toxins that you inhale while you smoke can add to the decaying state of your liver.
Do Not Let Everything Go Into Your Stomach: Watch what you eat. Lowering down the intake of sugar, processed food, and saturated foods can help your liver to heal. Adding fresh fruits and vegetables to your diet can contribute to an overall healthier body.
Plan Your Exercise Routine: When you exercise regularly, you are more likely to keep your weight in control. Exercises also improve your immune system and reduce the risk of liver cancer.
Do Not Take over-the-counter Conventional Medications: Over-the-counter medications can be really bad for your liver. There are certain allopathic medicines which when taken in combination can become toxic for your liver and normally you are less likely to know about these reactions. These medicines can cause your liver to work harder.
Take in an Ayurvedic Herbal Product to Cleanse Your Liver: Ayurvedic herbal product that gives natural curcumin supplementation to your body can help in healing your liver. Such an ayurvedic herbal product is manufactured by Preserva Wellness and is known by the name of Platimore Juice. This health tonic contains aloevera pulp, papaya, giloy, mandukaparni, Tulsi with natural curcumin supplement. With each of its ingredients being hepato-protective in nature, Platimore Juice by Preserva Wellness helps in preventing the liver from damage induced by alcohol. Various researchers have concluded that including curcumin as a dietary supplement has a protective role against the onset of liver diseases. Keep your liver safe from alcohol with Preserva Wellness!
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The advantages of vitamin supplements
Most other people don't need to take nutrition supplements, however in some situations, taking the drugs would possibly provide well being advantages.
Are vitamin supplements (like diet D) good on your health, and can you tell me who may get pleasure from taking the capsules?
Most people living in evolved international locations and consuming a balanced nutrition don't want a day by day multivitamin or specific nutrition drugs—however there are eventualities where we do.
Women of childbearing age must take a folic acid tablet each day (in the range of zero.four to zero.five micrograms). Folic acid dietary supplements protect against young children being born with neural tube defects. The worth of folic acid dietary supplements in pre-venting most cancers and center illness, which have been suggested via research 20 years ago, has now not been confirmed by way of randomized trials. shop Vitamins Online at Best price.
People who're at larger risk for growing osteoporosis (most older adults) are likely to have the benefit of a regular nutrition D complement. Authorities range as to the dose. In my opinion, a dose of one,000 global units (IU) in line with day is most often recommended and protected.
In creating nations, vitamin A supplements cut back death rates in youngsters. However, they are useless in advanced countries like the United States.
Some folks want nutrition supplements as a result of they've explicit scientific conditions that can result in deficiencies. People who should not have a typical balanced diet—as a result of they're poor, abuse alcohol, or have dietary restrictions (like being vegans), for example—might smartly need explicit vitamin drugs. The identical is right for other people with more than a few gut prerequisites—like Crohn's illness, celiac disease, chronic diarrhea, or gastric bypass surgical procedure—that intrude with the absorption of nutrients in food. People on dialysis for kidney failure need diet supplements. Adults of every age who get little or no exposure to sunlight—as an example, those that are homebound or in an institution—might need diet D supplements.
There are some people who find themselves born with a genetic situation that interferes with the metabolism of B vitamins. I'm considered one of them. People like us wish to take a high-dose vitamin B supplement each day.
Even if taking common diet pills has no longer proved to be really helpful for many folks, is it damaging? Taking one multivitamin a day virtually without a doubt isn't harmful, until the tablet accommodates a dose of nutrition A that is higher than 2,500 IU or a dose of nutrition E this is higher than 30 IU. High daily consumption of nutrition A (more than 10,000 IU) can increase the risk of start defects and osteoporosis. Beta carotene pills building up the danger of lung most cancers in people who find themselves already at increased possibility (like smokers). Daily diet C pills would possibly increase the risk of kidney stones.
Finally, the evidence about vitamin capsules is not all in. For instance, several theoretical health benefits from common nutrition D tablets are being examined in huge research. We will keep you up to date about important new research.
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Content Summary: [Ocultar] 1 Home remedies for hair loss 2 The key is in proper nutrition 3 The most important vitamins for hair 4 Home remedies for hair loss 5 Apple cider vinegar with sage tea 6 Carrot juice and coconut milk 7 Sweet almond oil and castor oil 8 Flaxseed Water 9 Brewer's yeast 10 Other tricks for strong hair Home remedies for hair loss Hair loss is a natural process that must occur, that is, hair has a life, and therefore must fall. The problem is when the hair loss is massive or is caused by causes derived from a deficit of vitamins, aggressive medical treatments or nervous states. Generally, both men and women are very alarmed when our hair falls out because it greatly affects the personal image, beautiful hair is a sign of health. But we must know that other factors that can modify our image interfere, even if we maintain health. With this, we refer to the genetic factors, which make hair loss accelerate, and although not much can be done in the face of genetic action; If we can stop and stabilize the fall trying not to lose the life of the hair follicle so that the hair grows back. For all this, and much more we offer below everything necessary to show off healthy hair, prevent its fall and recover its growth, getting it to take body and volume. The key is in proper nutrition Mainly the hair, it is nourished by vitamins and minerals and it is these that make its growth possible, also slow down the processes of massive hair loss and revitalize the follicle so that it continues to maintain the hair and does not fall out. For this, it is necessary to nourish the body from within. And as we usually say, to be well on the outside; We must be well inside. The hair is one of the areas where nutritional and nutrient deficiencies are appreciated. Generally, when we alter the food we notice it in the first instance in the skin, in the hair and in the nails. Therefore, we must try to eat healthy, with balanced diets in which fruits, vegetables, products of plant origin predominate, without forgetting fish and meat, as well as fats of plant origin; They are the healthiest. The most important vitamins for hair Biotin (Vitamin b7) You can see that many shampoos are enriched with biotin to achieve accelerated hair growth, improving their health and appearance. This vitamin is found naturally in nuts, brown rice, brewer's yeast, and oat flakes. It is essential for good hair health not to have vitamin B7 deficits, so we recommend incorporating certain foods rich in this vitamin into our diet or taking it as a supplement to ensure proper nutrition. Iron is one of the minerals in which it is easy to present deficits, especially in women for the fact of menstruation and that is why we must analytically review the values of iron because it can affect hair loss. This also happens if we have a vitamin C deficiency, since this vitamin contributes to the correct absorption of iron. Therefore, we must combine our diet with products that provide us with vitamin C and iron. For this, we recommend you include in your diet green leafy vegetables, broccoli, nuts, legumes, oats, strawberries, citrus fruits, pineapple, kiwi, papaya, etc. Mainly these three vitamins are the ones that most influence hair loss but we must bear in mind that if we provide our body with all the nutrients, vitamins and minerals that it needs, it can develop normally, which implies that it will guarantee a state of health optimum. Home remedies for hair loss These remedies that we offer below are tricks transmitted from generation to generation that contribute to a correct hair health, since they help with their properties to show radiant, healthy, strong and shiny hair, in addition to preventing hair loss. These grandmother's tricks are very effective if we are constant and combine it with good nutrition from the inside. Take note of all of them and try them, because they will not disappoint you. Apple Cider Vinegar with Sage Tea This remedy is very simple, and it is that apple cider vinegar contains sulfur, a very important mineral for hair and sage is used by different civilizations to enhance hair growth. Importantly, this remedy is not recommended for blonde people, since sage tends to darken the hair a bit. We must apply a mixture of the two ingredients mentioned and let it act, at least for approximately 8 hours. Carrot juice and coconut milk We can use milk or coconut butter, depending on the level of fat in our scalp and natural carrot juice to apply it to our hair, leave it on for at least an hour and wash our hair as usual. The carrot gives us vitamins of group B, which charge us with antioxidants that favor hair health, just as coconut milk is a powerful hair moisturizer. To repair punished tips you can use coconut oil, a foolproof trick for brittle tips. Sweet almond oil and castor oil This remedy is very effective for hair loss, but it is important to note that sometimes it can be a bit awkward to perform because of the fact it gives us. We recommend mixing two tablespoons of almond oil with a tablespoon of castor oil and giving a hair massage with circular movements and leaving for 15 minutes before washing your hair normally. Almond oil has an important source of proteins of vegetable origin ideal for hair health, and castor oil has a very important function that is to promote circulation; So it stimulates blood circulation in the scalp revitalizing the hair follicle. Evening primrose oil can help you stop the persistent fall, you should do a scalp massage, leave it on for about 15 minutes and wash your hair as you usually do. If you have dry hair you can add some evening primrose oil in your shampoo since it will act as a moisturizer, but if you have oily hair it is not advisable to do so since it will increase sebum production. Flaxseed Water This drink is rich in omega 3 acids and contains essential acids that contribute to hair health and hair growth, so it is advisable to drink a glass of flaxseed water in the morning. Beer yeast Brewer's yeast is known worldwide to ensure beautiful hair, and much of the shampoos and conditioners incorporate it into its formulas. You can help extra by adding a teaspoon each morning in your yogurt or juice. It has no flavor and hardly adds calories, so it is ideal and very easy to consume. Other tricks for strong hair During pregnancy, women presume to have stronger, prettier and healthier hair and it is that hormones play their part and in fact, we can say that during this state the hair grows faster. It is also true that all pregnant women take dietary supplements of iron and other vitamins, as well as folic acid and iodine that contribute to the lack of nutrients in our body, so hair health is reinforced. It is for this reason that we can find on the internet different tricks to show off beautiful hair, and among them, the fact of adding contraceptive pills to the shampoo is widespread since they say they maintain hair health and achieve faster hair growth. To check the effects there is nothing more effective than to test them on yourself, so here we have made a compilation of the best tricks and remedies to stop hair loss. Soon in new entries, we will talk about other hair tricks, do not miss them. Click here for more tips
http://bestofftops.blogspot.com/2019/09/home-remedies-for-hair-loss.html
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THE MOST IMPORTANT VITAMIN IN YOUR BODY
New Post has been published on https://newscheckz.com/the-most-important-vitamin-in-your-body/
THE MOST IMPORTANT VITAMIN IN YOUR BODY
Vitamins and minerals are considered essential nutrients because acting in concert, they perform hundreds of roles in the body.
They help shore up bones, heal wounds, and bolster your immune system. They also convert food into energy, and repair cellular damage.
What is the most important vitamin for your body?
Magnesium – This mineral plays an important role in muscle contractions. …
Calcium – This mineral is very essential for bone and teeth health. …
Vitamin C – This water-soluble vitamin plays important roles in immune system function. …
Vitamin B-12 – This is one of the most important essential vitamins.
VITAMIN A. GOOD FOR: Healthy eyes and general growth and development, including healthy teeth and skin. …
B VITAMINS. GOOD FOR: Energy production, immune function and iron absorption. …
VITAMIN C. …
VITAMIN D. …
VITAMIN E. …
VITAMIN K. …
FOLIC ACID. …
CALCIUM.
Is it important to take vitamins?
Most people do not need to take vitamin supplements and can get all the vitamins and minerals they need by eating a healthy, balanced diet.
Vitamins and minerals, such as iron, calcium and vitamin C, are essential nutrients that your body needs in small amounts to work properly.
What vitamins do we need daily?
According to Nutritionists, These Are some of Ingredients Your Multivitamin Should Have
Vitamin D. Vitamin D helps our bodies absorb calcium, which is important for bone health. …
Magnesium. Magnesium is an essential nutrient, which means that we must get it from food or supplements. …
Calcium. …
Zinc. …
Iron. …
Folate. …
Vitamin B-12.
What vitamins can be made by the human body?
Vitamins-what vitamins the body produces. The human body can produce vitamin D and vitamin K. Vitamin K is a vitamin that acts in the liver, affecting the manufacture of the substances that makes the blood.
Does multivitamin increase weight?
By taking multivitamins, there’s an increased chance that your body will have all the nutrients it needs to function properly.
This may impact upon your weight because of its effect on the metabolism, which is assisted by a wide variety of nutrients.
What happens when you start taking vitamins?
You might experience transient digestive upset when you first start out. It’s very common to experience this side effect when you start a supplement regime and typically it happens when you take your vitamins on an empty stomach.
Does multivitamin have side effects?
When taken as directed, multivitamins are not expected to cause serious side effects. Common side effects may include: upset stomach; headache among others.
Can I take vitamins at night?
Medics suggests taking your dietary supplements at night isn’t advisable. “Digestion slows down during sleep, so taking your nutrient supplement late at night would not be associated with an efficient absorption.”
How can a skinny person gain weight?
Don’t drink water before meals. This can fill your stomach and make it harder to get in enough calories.
Eat more often. …
Drink milk. …
Try weight gainer shakes. …
Use bigger plates. …
Add cream to your coffee. …
Take creatine. …
Get quality sleep.
What happens if you take vitamins everyday?
A recent study of 14,000 men aged 50 and older found that daily multivitamin supplementation “significantly reduced the risk of total cancer.”
Boosts immunity: Vitamin C is a strong antioxidant known for strengthening the immune system. Vitamins D and E boost immunity, too.
What does multivitamin do to your body?
The vitamins and minerals in your daily multivitamin can also significantly reduce levels of stress and anxiety.
The body uses B vitamins to convert food into energy, keep the nervous system functioning properly, and to produce stress hormones.
Taking multivitamins daily can replenish your body’s supply.
What vitamins actually work?
A team of researchers in Canada found that common supplements such as multivitamins, vitamin D, calcium and vitamin C provide no protection against heart disease, heart attack, stroke or premature death.
Folic acid and B-vitamins were associated with a reduced risk of heart disease and stroke.
Does multivitamin make you sleepy?
After controlling for age, sex and other variables, the scientists found a slightly higher rate of poor or interrupted sleep in people taking multivitamins.
Do multivitamins actually work?
If you take a multivitamin, it’s probably because you want to do everything you can to protect your health.
But there is still limited evidence that a daily cocktail of essential vitamins and minerals actually delivers what you expect.
Most studies find no benefit from multivitamins in protecting the brain or heart.
Which fruits increase weight?
Fruits that help in gaining weight naturally
Mango. One of the most delicious fruits, mango is a rich source of several nutrients such as copper, vitamin B, and vitamin A and E. …
Bananas. If you want perfect muscles, then bananas happen to be the best choice. …
Coconut. …
Dried fruits. …
Avocados This exotic fruit is great for someone who wants to gain weight.
What foods help you gain weight?
Homemade protein smoothies. Drinking homemade protein smoothies can be a highly nutritious and quick way to gain weight. …
Milk. Milk has been used as a weight gainer or muscle builder for decades (1). …
Rice. …
Nuts and nut butters. …
Red meats. …
Potatoes and starches. …
Salmon and oily fish. …
Protein supplements.
How long do vitamins stay in your body?
Vitamins Hang Out in Water and Fat
They wait around in your body fat until your body needs them. Fat-soluble vitamins are happy to stay stored in your body for awhile, some stay for a few days, some for up to 6 months!
Is multivitamin good for skin?
Vitamin D is one of the best vitamins for your skin, along with vitamins C, E, and K. Making sure you get enough vitamins can keep your skin looking healthy and youthful. This could translate to a reduction in: dark spots.
Are vitamins a waste of money?
Most vitamins may be a waste of money, but study finds two exceptions. The majority of vitamins and other nutritional supplements don’t increase lifespan or protect one’s heart health, a huge analysis out of Johns Hopkins University has found.
What is the No 1 food supplement in the world?
USANA
2, 2019 /PRNewswire/ — USANA, a leader in the health and wellness industry, was named the number one vitamin and dietary supplement brand in Philippines*.
This claim was granted by Euromonitor, the world’s leading provider for global business intelligence, market analysis and consumer insights.
Can I take all my vitamins at once?
Combining supplements will not normally interfere with the way they work and in some cases may be beneficial, for example vitamin C helps iron absorption.
However, certain supplements may interact with each other.
Is Centrum a good vitamin?
Centrum One A Day Men’s Health Formula
One tablet of this multivitamin includes all essential nutrients for men, except iron.
However, it provides less than 100% of the RDI for several important nutrients, including thiamine, niacin, biotin, calcium, magnesium and vitamins A, E and K.
Which fruit is good for skin glow?
The best sources are blackcurrants, blueberries, broccoli, guava, kiwi fruits, oranges, papaya, strawberries and sweet potatoes.
Vitamin C is needed to produce collagen that strengthens the capillaries that supply the skin. Read more about vital vitamins and the health benefits of oranges.
Which fruit is high in sugar?
Watermelon
A medium wedge of this summer treat has 17 grams of sugar. As its name suggests, it’s loaded with water, and it has special minerals called electrolytes that are just what your body needs to recharge after some time in the sun. Just keep it to a slice or two.
Does banana make you fat?
Let’s just make it clear here itself that bananas in themselves are not fattening. In fact, banana can help in losing weight as they have high fibre content and also have a good number of calories.
Even during weight loss, your body needs a certain number of calories which should not come from unhealthy foods.
Does milk make you gain weight?
The creation of low fat and no fat dairy products has further added to the belief that dairy foods are fattening.
But research shows that having enough milk, yoghurt and cheese every day, as part of a healthy diet, is not linked to weight gain.
How can a woman gain weight in one week?
Consumption of energy-rich foods: Make sure to eat, energy-dense foods like nuts including almonds, walnuts, peanuts, dried fruits including raisins or prunes, dark chocolate, high-fat dairy foods like condensed milk, full-fat cream, cheese, milk, veggies like potatoes and yams, etc.
What is the most toxic of all vitamins?
Owing to their ability to accumulate in the body, fat-soluble vitamins have a higher potential for toxicity than do water-soluble vitamins.
Iron-containing vitamins are the most toxic, especially in pediatric acute ingestions
Which vitamin makes skin white?
Vitamin C helps to lighten and brighten skin naturally to fight dark spots, while promoting collagen production and defending against free radical damage.
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Alternatives(8)
We now have seen both sides of the argument. Vegans argue that meat is bad for your health while researches on the “normal” diet believe that meat is vital. Is it possible to get the same nutrients that meat provides from plants? To start off I wan to have a clear understanding on what vitamins are the most important for consumption and what they do. When I searched “Nutrients needed to be healthy” on the library data base, I found an article that gave me just that.
The article gave a list of things that everyone should be having in their everyday diet.
A plays a crucial role in vision and may protect against some cancers.
B1, B2, and B3 help your body process carbs and protein.
B12 may reduce your risk of osteoporosis and Alzheimer's.
C keeps skin supple and helps your body absorb iron.
Calcium helps maintain strong bones, thus protecting against osteoporosis, and may aid in weight loss. In one study, people who ate three servings a day of low-fat yogurt lost 60 percent more fat than those who didn't eat dairy.
D aids your body's calcium absorption.
E helps your brain and eyes stave off disease. It may also decrease the risk of death from heart disease.
Folic acid may lower blood pressure, and taking it before conception and while pregnant can slash birth-defect risk by as much as 70 percent. Note: This is the only nutrient your body actually absorbs better from a pill than from food.
Iron combats fatigue and increases blood circulation.
Zinc is necessary for maintaining your sense of smell and healing wounds. Some studies have found that taking zinc can shorten the duration of the common cold, too.
So if one can get these vitamins in the vegan diet, there would be no reason to not give it a shot. I found an article that shows that plants have all the same nutrients that meat have. The post was written by Heather McClees, a certified nutritionist and dietetic specialist, and who has a B.S. in Nutrition Science and Dietetics and has been a plant-based eater for 10 years. The website is called:
http://www.onegreenplanet.org/natural-health/nutrients-found-in-meat-you-can-get-from-plants-instead/
I have already used this website for a different research topic earlier and I believe it is credible because the organization has over 6 million visitors and is the largest vegan website. In the article that McClees wrote that many people are against the vegan lifestyle because of the lack of vitamins that they believe are only in animal products. McClee argues that all of the same vitamins can be found in plants by making sure these foods are in your diet!
Protein: Says that seed protein is way easier to digest than meat protein, also says that animal based protein is inflammatory. You can find protein in hemp seeds, chia seeds, pumpkin seeds, quinoa, oats, almonds or almond butter, leafy greens, broccoli, green beans, lentils, black beans, chickpeas, green peas, and even raw plant-based protein powder if you enjoy smoothies. And of course, tofu and tempeh are also great choices if you tolerate soy.
Iron: Very easy to obtain in plants. Can find iron in hemp seeds or hemp protein, raisins, cashews, kale, pumpkin seeds, kaniwa, spirulina, beans, prunes, legumes, oats, quinoa, amaranth, teff, chia seeds, blackstrap molasses, cacao, tempeh, and sunflower seeds
Zinc: Can be found in pumpkin seeds, sesame seeds (or tahini), cashews, hemp, pintos, lentils, almonds, oats, quinoa, sunflower seeds, chia seeds, cacao, tofu, chickpeas, kidney beans and green peas.
Calcium: Most people are scared to give up dairy because they think they wont get calcium but plants do not cause inflammations, interfere with magnesium absorption, or cause calcifications on bones. Calcium can be found in kale, collards, spinach, Swiss chard, oranges, dried figs, chia seeds, almonds, teff, navy beans, fortified non-dairy milk, most beans, and tofu.
B12: She says that b12 is hard to get through plants(and through animal products also) so she suggests taking supplements.
Other B Vitamins: Can be found in greens, vegetables, fruits, nuts, seeds, beans, avocados, legumes, and whole grains.
Vitamin D: She says that even milk is fortified with the vitamin, that it is not natural. She suggests eating mushrooms or drinking non-dairy fortified milk or taking a supplement.
In one last research article I that I found through the library database a study was constructed around four different diet styles: the control, vegetarian, vegan, and methionine restricted diet. All subjects were a 20 year old male with standard height and weight. The study recorded foods with frequent occurrence across irreducible food sets which provide very balanced amounts of different nutrients, and would be classified as having high nutritional fitness (NF).
They found that across all four diets, the most common foods with the highest NFs were almond, chia seeds, and cherimoya. These food are all largely consumed by the vegan diet. It was also found that lima beans and green peas served as a great replacement for meat protein.
The study also showed which diets lacked certain nutrients.
All of the diets lacked Choline, Vitamin B, and Vitamin E. Vegan lacked in Selenium, Methionine, and Protein.
This research study showed how each diet has certain food that have high nutritional fitness levels and all are lacking some nutrients. How can we be sure which diet is best when each is lacking something?
McClees, Heather. “Nutrients Found IN Meat That You Can Get From Plants Instead”. One Green Planet, http://www.onegreenplanet.org/natural-health/nutrients-found-in-meat-you-can-get-from-plants-instead/. Accessed 17 April 2018
Asp, Karen. “Get The Nutrients You Need.” Redbook, https://web-a-ebscohost-com.proxy.uwec.edu/ehost/detail/detail?vid=0&sid=9b435255-8229-4c69-93f4-2ac3758d36f0%40sessionmgr4008&bdata=JkF1dGhUeXBlPWlwLHVpZCZzaXRlPWVob3N0LWxpdmUmc2NvcGU9c2l0ZQ%3d%3d#AN=19938657&db=ulh. Accessed 17 April 2018
Fenech, Michael F.. “Nutritionally Recommended Foods For Semi- to Strict Vegetarian Diets Based On Large Scale Nutrient Composition Data.” Scientific Report, http://www.nature.com.proxy.uwec.edu/articles/s41598-018-22691-1#Abs1. Accessed 17 April 2018
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