#anaphylaxis filter

[metsn]

ANAPHYLAXIS FILTER - WASPsynth multi-mode filter with double LFO and distortion

The ANAPHYLAXIS FILTER is a multi-mode filter with double LFO modulator for the CUTOFF frequency based the filter section of the notorious WASP synthesizer that was created by Electric Dream Plant in 1978. This standalone pedal version of the filter allows you to use it for the input signals of your choice. The FILTER MODE selector is a 4 position rotary switch (up to down: LOW PASS, BAND PASS, HIGH PASS and NOTCH) with the position indicated by small purple UV LEDs. The input signal is controlled with the GAIN control, that can boost even weaker input signal to overdrive the filter. A dedicated RESONANCE control determines the amount of RESONANCE  at the CUTOFF point, that of course has a control knob as well. Furthermore the RESONANCE has two settings: EXTREME (up) and NORMAL(down), selected with a toggle switch. In HIGH PASS mode the filter can self-oscillate without any input, in case you need a high frequency SINE WAVE oscillator. In that case the FREQUENCY can be dialed in with the CUTOFF control. A 3.5mm mono input socket for EXTERNAL CV (Beware only use max. +5VDC, everything else destroys the circuit!). This input is used to modulate the filter’s CUTOFF with external gear (as i demonstrate in a demo video of a previous build). But the ANAPHYLAXIS FILTER can do more, as it has 2 build in LFOs that are modulating the CUTOFF frequency, with independent SPEED and DEPTH controls, which allows to generate a more complex modulation waveform. Each LFO has a RANGE toggle that selects: SLOW (down) or FAST (up) as well a 3 position toggle switch that selects the SHAPE: SQUARE (down), OFF (middle) and triangle (up). The fast LFO range goes well into audio range and enables you to create  some very interesting frequency modulation filter effects. With slower rates, especially with the triangle shape and the 2 LFOs running at non-synced rates, even the most static sounding input get ‘alive’. The SPEED of each LFO is indicated by either red or green color in the big LED in the middle of the LFO section. The 1st stomp switch is TRUE BYPASS and if that is not enough, the 2nd stomp switch engages the DISTORTION, both with UV indicator LEDs. The level of the DISTORTION is controlled by the DISTORTION knob and the toggle switch next to it adds a TREBLE BOOST (up) or a HIGH CUT (down) setting to the DISTORTION. In the end of the signal path is a signal booster based on the EHX LBP1 with a global VOLUME control. The ANAPHYLAXIS FILTER runs on 9V DC and has a ‘boss style’ 2.1mm DC barrel plug socket with the negative pin inside. The enclosure is a heavy duty scavenged industrial engine power connector housing made from die-cast aluminum with a bottom plate made from found material and is painted in the industrial burnout camo pattern in matte black and bright yellow. Handmade by GRM for METSÄÄN. Sold.

[thebibliosphere]

tw: content under a cut for talking about calorie counting (in a positive way), restrictive medical diets, and MCAS 'remission.'

So it's been 5 months since I last saw the GI doctor who took me seriously regarding my mast cell dysfunction, and not only have I gained a LOT of foods back into my diet under his care without experiencing idiopathic anaphylaxis, but I've also managed to eat 2000 calories almost every day for the last 5 months.

Prior to his care, since 2020, I had been mostly surviving on a liquid diet with the odd bit of solid carbs and protein when I could handle it.

Which was better than the 2 things I could digest safely prior to 2019, which were oatmeal and filtered tap water toward the end when I was dying. But even after I recovered from that, any time I went over 700 calories a day in solid food, I'd be writhing in pain.

I still have days when the pain hits, and all I can manage is liquids, but those days are so much less, and thanks to being able to eat more foods, I can at least liquidate more nutrients to make sure I'm getting what I need.

Things will never be 100% healed. That's not the nature of this kind of immune disease. But they're better. I'm better. I'm still so scared to say any of this is in remission because MCAS is wildly unpredictable. But I'm so much better than I was.

And I'm going to go happy-cry and eat a gluten-free cupcake about it.

[phunockery]

Trigger warning allergic reaction, random etymology facts pertaining to sexual acts, talking about death, the melodrama of trying not to die.

(Spoilers) If you're reading this, it means I survived the night.

This is a timed log after finding out I poisoned myself. I don't think I'll die from it but this sucks and I'm feeling emotional and melodramatic.

11:00ish

If I die tomorrow, I didn't mean to. I promise. I just wanted a drink. I usually don't, it usually upsets my stomach. But tomorrow I turn 34 and I was feeling frisky and wanted something to drink while I play my traditional birthday (and sad mood) game: Sonic 2. So I grab a Kirkland hard seltzer from the fridge. Never tried the brand, but it was black cherry and I like that.

I decided to try to time some of my runs, nothing serious. Beat a couple of my pbs feeling good.

After drinking about 1/4th of the seltzer and I notice that my head is feeling funny and I wonder how a 5% drink was making me feel like that. My game play gets bad, but I beat my PB on Chemical Plant 2.

Aquatic Zone is a mess, mild improvement in act 2... And I start feeling itchy. Hives are building. I grab some Benadryl, chew two and as my chest tightens I look up what could be causing this.

11:15

Apparently there is a filtering process called finning that run the alcohol through animal products, like gelatin.

That comes from pigs.

That I am deathly allergic to.

The company does not have to disclose this information and honestly this a best guess, because what else would make me allergic to an alcoholic beverage?

Now I am sitting here, trying to differenciate anxiety and anaphylaxis. Taking deep breaths, epi pen in hand. I'm not going to call 911 because I can't afford it, if you're mad, join the club. (🦅 Insert screams of eagles and freedom here 🇺🇲)

It's almost midnight. I am almost 34 and I am live blogging my allergic reaction because I have nothing else to do

'call 911' that is far too expensive and I don't want to leave my kids with massive amounts of debt because I decided to get treatment (eagle screaming and freedom noises here 🦅)

I messaged a few friends, but they're busy. My friend is probably going to kill me in the morning when she sees this if I'm not already dead.

I'll probably live... I once survived a wedding where the brides mother unintentionally tried to kill me. I was lucky then because there was a doctor in the house... But that was worse. I had lost my ability to breathe immediately.

I'm just itchy. Soooo itchy. I am covered in hives... It doesn't help that my other friend made dinner and no one put cast iron that has cooked bacon and allergy together yesterday... Which I suffered for. Granted I suffered less then than I am now. Now now, but still itchy and cramps.

11:30

I hope to make it to cramps. I should. I can still breath. I am just so itchy. I hate this. I should be getting rest so I can pretend to have a good birthday. Instead I will pretend to have a good birthday and deal with aaaallll the fallout of having a full allergic reaction.

11:35

Chest is no longer feeling tight. A friend has message saying they are going to bed. I sent a message asking if they have a few moments to just sit with me. I think it was too late, they're offline.

11:40 I'm still itchy. My legs, my arms, my scalp, my chest, my armpits... It all itches. This really sucks. (Remembers that sucks used to be a euphemism for bjs and this fact gives me the chuckles of strength).

11:45

double checked messages to other friends. All unread. Some are online, some are not. But I am still alone so you, future reader, remain my emotional support pen-pal.

The skin around my eyes is itchy like I was crying. I don't think I've been crying. I'm upset, but not like that.

Good news: this won't be my worst birthday.

My worst birthday was in 2009. I was BMT for the USAF and on my 19th birthday, two days before graduating, I was acting unusually confused, was sent to the hospital and diagnosed with viral meningitis. I was booted from the USAF shortly after recovering.

11:50 Hell this isn't even as bad the last 7 years that just got progressively worse. I was let go of my job on my 30th birthday and became disabled two days later. (Barely related). Last year I was coerced into going to a water park (I don't do good with loud noises any more) and I wound up breaking a tooth trying to swim in the shallow waters. My ex was not comforting about it and suggested that I not make a scene in front of my kids because they would get upset.

11:55 I can breathe a bit easier. Still left unseen and I turn 34 in 5 minutes.

3 minutes to go and I am trying to fight the sleepy of the Benny's until I feel less itchy.

2 more minutes, I really hope I don't die, my friends don't deserve to have a corpse in their guest room

12:05 made a happy birthday post on TikTok. My voice is definitely affected, but I can talk and breath.

Still left on unseen. I feel bad that they're going to wake up and find out that a friend reached out for help and help wasn't available. That is going to suck. Hopefully I'm still alive and can tell them they're good and deserve sleep.

12:20 a rando has become the first to wish me a happy birthday. A friend messaged to let me know they're glad I'm safe and they're going to bed so they can work in the morning. They hope I find someone to talk to. It looks like it is just you and me

12:23 the stomach has put in its bid for attention. I will spare you the details. The Benny's are taking effect. I am soooo tired and the body itches slightly less. Except around the eyes, it still feels like I've been crying

12:29 my apologies to my friend: I fear I have destroyed your toilet. It should be fine in the morning.

12:30 the stomach still hates me. I hate me. I just want to go to bed.

12:40 tired. Imma go to bed with my Epi Pen on the bedside table. I wake up to everything anyways. The sudden inescapable lack of breath should be more than enough to wake.

I could really use a 'there there's and a hug. And now my eyes are itchy again, at least I know why this time.

Good night.

[so-true-overdue]

The Indispensable Triumph of Vaccines: A Testament to Scientific Sagacity and Human Tenacity

Vaccines, those tiny syringes of salvation, are arguably the most unimpressive miracles of modern medicine to the ill-informed cynic. Yes, nothing screams "revolutionary breakthrough" like a preemptive strike against disease that saves millions annually, all while a vocal minority clamors about their “right” to invite polio back to the family picnic.

Let us begin with the staggering evidence: Vaccines have eradicated smallpox, a disease that once obliterated up to 30% of its victims and left survivors with scars not even Instagram filters could conceal. The World Health Organization estimates that immunizations prevent between 4 and 5 million deaths per year globally—numbers that could only be denied by those for whom counting to ten is a mental Everest. Diseases like measles, which once ravaged communities with impunity, have been reduced to near-irrelevance in regions with robust vaccine programs. The measles vaccine alone has averted 23 million deaths since the year 2000. Truly, what a mediocre accomplishment for humanity.

Of course, no discussion of vaccines is complete without acknowledging their alleged risks, because nothing bolsters a debate quite like hyperbole sprinkled with scientific illiteracy. Adverse reactions do exist—anaphylaxis, for instance, occurs in approximately one in a million doses. For the sake of comparison, your odds of being struck by lightning this year are about one in 500,000, meaning nature’s wrath is statistically a greater concern than a vaccine needle. But why let a paltry 0.0001% chance of discomfort stand in the way of eradicating pathogens that could otherwise ravage civilizations?

For the steadfast among us, who valiantly cling to the "but my freedoms!" battle cry, let us discuss the communal contract. Herd immunity, that great bastion of collective well-being, requires a high percentage of the population to be vaccinated to protect the immunocompromised and those unable to receive vaccines. If altruism feels like a stretch, consider that it also shields the selfish from their own ignorance. You're welcome.

The irony, of course, is that the anti-vaccine contingent relies on the very success of vaccines to support their unfounded arguments. When polio cases dwindle to statistical obscurity, it becomes convenient to dismiss vaccines as unnecessary. What a delightfully self-sabotaging cycle of logic: reap the benefits of scientific achievement while vilifying its methods.

In conclusion, vaccines are not just a triumph of medical science; they are a moral imperative. They represent the culmination of centuries of relentless research, collaboration, and sacrifice. To question their value is to willfully disregard mountains of data, spit in the face of public health, and, frankly, flirt with lunacy. So, by all means, let’s continue this enlightened debate—right after I go thank Pasteur and Jenner for allowing me to exist in a world where smallpox and rabies are no longer death sentences.

[drprashantgandi-1]

Discover expert tips on managing childhood allergies and asthma from Dr. Prashant Gandhi, a top pediatrician in Borivali West.

Childhood allergies and asthma are common concerns for parents, affecting millions of children worldwide. As a parent, navigating through the challenges of managing these conditions can be overwhelming. However, with the right guidance and proactive measures, you can effectively support your child's health and well-being. In this article, we'll explore practical strategies and expert advice on managing childhood allergies and asthma.

Understanding Childhood Allergies and Asthma:

Childhood allergies refer to hypersensitive reactions to certain substances, such as pollen, dust mites, pet dander, or certain foods. These allergic reactions can manifest in various forms, including skin rashes, nasal congestion, itching, or even anaphylaxis in severe cases. On the other hand, asthma is a chronic respiratory condition characterized by inflammation and narrowing of the airways, leading to symptoms like wheezing, coughing, chest tightness, and shortness of breath.

Expert Tips for Managing Childhood Allergies and Asthma:

Consult a Pediatrician: The first step in managing childhood allergies and asthma is to consult a pediatrician or child specialist near you. Dr. Prashant Gandhi, a renowned pediatrician in Borivali West, specializes in providing comprehensive care for children with allergies and asthma. Schedule regular check-ups to monitor your child's condition and receive personalized treatment recommendations. Identify Triggers: Work with your pediatrician to identify potential triggers that exacerbate your child's allergies or asthma symptoms. Common triggers include pollen, dust, pet dander, mold, certain foods, or respiratory infections. By minimizing exposure to these triggers, you can help reduce the frequency and severity of allergic reactions and asthma flare-ups. Create an Allergy-Friendly Environment: Make necessary adjustments to create an allergy-friendly environment at home. Use allergen-proof mattress and pillow covers, regularly clean and vacuum your home to reduce dust and pet dander, and consider investing in an air purifier with HEPA filters. These simple measures can significantly improve your child's respiratory health and overall comfort. Follow Asthma Action Plan: If your child has asthma, work with your pediatrician to develop an asthma action plan outlining specific steps to take in case of an asthma attack. This plan should include instructions on using rescue inhalers, recognizing early warning signs of an asthma flare-up, and when to seek emergency medical care. Stay Up-to-Date with Vaccinations: Vaccinations play a crucial role in preventing certain respiratory infections and complications associated with allergies and asthma. Visit a vaccination center in Borivali West, like Dr. Prashant Gandhi's clinic, for timely vaccinations, including HPV vaccine, polio vaccine, and other routine immunizations recommended for children.

Aayushi children's clinic and vaccination centre | Dr. Prashant Gandhi

Address: Aayushi clinic, A/306,mangal aarambh near mc Donald, s, RM Bhattad Rd, opp. Kora Kendra Ground 2, Borivali West, Mumbai, Maharashtra 400092

Phone: 097020 70304

[comprehensive-ent-centre]

The immune system, responsible for safeguarding health, can sometimes misidentify harmless substances as threats, triggering allergies. Allergens, like pollen or certain foods, induce immune responses leading to symptoms such as sneezing, congestion, hives, or even severe reactions like anaphylaxis. Allergies can be inhalant or ingestant, affecting the respiratory or digestive systems. Seasonal allergies cause hay fever symptoms, while food allergies may result in nausea, vomiting, or skin issues. Skin allergies, often from insect bites, lead to redness and swelling. Drug allergies can cause varied symptoms, including wheezing and swelling. While no permanent cure exists, management options include medications, immunotherapy, and lifestyle adjustments. Identifying and avoiding allergens, using saline rinses, HEPA filters, and dehumidifiers, along with essential oils and proper hygiene, form part of home-based strategies. For severe cases, immediate medical attention, especially from an ENT specialist, is crucial. Understanding allergens empowers individuals to proactively manage allergies, leading to a healthier life despite allergic sensitivities.

[myjerseysgo]

Swing for the Fences

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https://www.pr0digy.com

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[healthcaretipsdailyforyou]

Allergies and Allergen Management: Understanding, Avoiding, and Treating Allergic Reactions

Introduction: Allergies affect a significant portion of the global population, leading to a range of uncomfortable symptoms that can disrupt daily life. An allergic reaction occurs when the immune system overreacts to a harmless substance, known as an allergen. From seasonal allergies to food sensitivities, these immune responses can cause sneezing, itching, hives, digestive issues, and even life-threatening anaphylaxis. In this blog post, we will explore common allergies, provide essential tips for avoiding allergens, and discuss available treatment options to help individuals effectively manage their allergies.

Common Allergies: Allergies can stem from various sources, but some of the most prevalent ones include:

a) Seasonal Allergies: Pollens from trees, grasses, and weeds are common triggers for seasonal allergies, leading to symptoms like sneezing, runny nose, itchy eyes, and congestion.

b) Food Allergies: Allergic reactions to certain foods, such as peanuts, tree nuts, shellfish, eggs, milk, wheat, and soy, can range from mild discomfort to severe anaphylaxis.

c) Pet Allergies: Proteins found in pet dander, saliva, or urine can cause allergic reactions in some individuals, leading to respiratory symptoms and skin rashes.

d) Dust Mite Allergies: Microscopic organisms present in dust mites can trigger allergic reactions, particularly in individuals with asthma or respiratory conditions.

e) Insect Sting Allergies: Venom from stinging insects like bees, wasps, and hornets can cause severe allergic reactions in some people.

Tips for Avoiding Allergens: While complete avoidance of allergens may not always be possible, several strategies can help minimize exposure and reduce the likelihood of allergic reactions:

a) Identify Triggers: Work with a healthcare professional to identify specific allergens through allergy testing. Knowing your triggers is essential for effective allergen management.

b) Create Allergen-Free Zones: Designate certain areas of your home as allergen-free zones, especially bedrooms, where you spend a significant portion of your time.

c) Regular Cleaning: Regularly clean your living spaces, using a vacuum cleaner with a HEPA filter to trap allergens. Wash bedding and curtains frequently in hot water.

d) Pollen Awareness: Stay informed about pollen levels in your area and try to limit outdoor activities during peak pollen times.

e) Food Labels: Read food labels carefully to avoid allergens and cross-contamination in packaged products.

f) Pet Care: Bathe and groom pets regularly to reduce dander, and designate pet-free areas in your home.

Available Treatment Options: When prevention is not sufficient, various treatment options are available to manage allergies:

a) Medications: Antihistamines, decongestants, nasal corticosteroids, and eye drops can provide relief from allergy symptoms.

b) Immunotherapy: Allergen immunotherapy, commonly known as allergy shots or sublingual tablets, can help desensitize the immune system to specific allergens over time.

c) Emergency Medication: Individuals with severe allergies should carry an epinephrine auto-injector (EpiPen) for emergency use in case of anaphylaxis.

d) Avoidance and Lifestyle Changes: As mentioned earlier, avoiding allergens is the first line of defense in managing allergies effectively.

Finding Support at Top Hospitals in Hyderabad: For individuals seeking comprehensive allergy diagnosis and treatment, consulting with top hospitals in Hyderabad can provide expert medical guidance and support. These hospitals offer advanced allergy testing, personalized treatment plans, and access to experienced allergists to help patients effectively manage their allergies.

Conclusion: Allergies can significantly impact an individual's well-being, but with proper allergen management and the right treatment plan, individuals can experience relief and lead fulfilling lives. Understanding common allergens, taking preventive measures, and seeking medical advice from top hospitals in Hyderabad can help individuals effectively manage their allergies. If you suspect allergies are affecting your health, consult with a healthcare professional to determine the appropriate course of action and regain control over your allergic reactions.

[metsn]

ANAPHYLAXIS FILTER - WASPsynth multi-mode filter with double LFO and distortion (#3.2024)

The ANAPHYLAXIS FILTER is a multi-mode filter with double LFO modulator for the CUTOFF frequency based the filter section of the notorious WASP synthesizer that was created by Electric Dream Plant in 1978. This standalone pedal version of the filter allows you to use it for the input signals of your choice. The FILTER MODE selector is a 4 position rotary switch (up to down: LOW PASS, BAND PASS, HIGH PASS and NOTCH) with the position indicated by small purple UV LEDs. The input signal is controlled with the GAIN control, that can boost even weaker input signal to overdrive the filter. A dedicated RESONANCE control determines the amount of RESONANCE at the CUTOFF point, that of course has a control knob as well. Furthermore the RESONANCE has two settings: EXTREME (up) and NORMAL(down), selected with a toggle switch. In HIGH PASS mode the filter can self-oscillate without any input, in case you need a high frequency SINE WAVE oscillator. In that case the FREQUENCY can be dialed in with the CUTOFF control. But the ANAPHYLAXIS FILTER can do more, as it has 2 build in LFOs that are modulating the CUTOFF frequency, with independent SPEED and DEPTH controls, which allows to generate a more complex modulation waveform. Each LFO has a RANGE toggle that selects: SLOW (down) or FAST (up) as well a 3 position toggle switch that selects the SHAPE: SQUARE (down), OFF (middle) and triangle (up). The fast LFO range goes well into audio range and enables you to create some very interesting frequency modulation filter effects. With slower rates, especially with the triangle shape and the 2 LFOs running at non-synced rates, even the most static sounding input get ‘alive’. The SPEED of each LFO is indicated by either red or green color in the big LED in the middle of the LFO section. The 1st stomp switch is TRUE BYPASS and if that is not enough, the 2nd stomp switch engages the DISTORTION, both with UV indicator LEDs. The level of the DISTORTION is controlled by the DISTORTION knob and the toggle switch next to it adds a TREBLE BOOST (up) or a HIGH CUT (down) setting to the DISTORTION. In the end of the signal path is a signal booster based on the EHX LBP1 with a global VOLUME control. The ANAPHYLAXIS FILTER runs on 9V DC and has a ‘boss style’ 2.1mm DC barrel plug socket with the negative pin inside. The enclosure is a heavy duty scavenged industrial engine power connector housing made from die-cast aluminum with a bottom plate made from found material and is painted in the industrial burnout camo pattern in matte black and bright yellow. Handmade by GRM for METSÄÄN.

Buy link. (links to webshop.)

[laocommunity]

Miracle Drug: Febuxostat Decreases Risk of Life-Threatening Kidney Condition in Late Stage CKD Patients

Miracle Drug: Febuxostat Decreases Risk of Life-Threatening Kidney Condition in Late Stage CKD Patients Miracle Drug: Febuxostat Decreases Risk of Life-Threatening Kidney Condition in Late Stage CKD Patients Introduction Chronic kidney disease (CKD) is becoming increasingly common, affecting over 10% of the global population. Late stage CKD is particularly concerning, as it is associated with a significantly increased risk of life-threatening kidney complications. However, a new miracle drug has emerged that offers hope for late-stage CKD patients. Febuxostat, a medication that blocks the production of uric acid, has been found to decrease the risk of these complications in these patients. The Importance of Late Stage CKD Late stage CKD is a serious condition that affects the kidneys' ability to filter waste and excess fluids from the blood. This can lead to high levels of toxins and electrolytes in the blood, which in turn can cause a range of life-threatening complications, including heart disease and stroke. Late stage CKD is particularly worrisome because it often goes undetected until it is very advanced, meaning that many patients are already at a high risk of these complications. The Role of Uric Acid Uric acid is a waste product that is formed when the body breaks down purines, which are naturally occurring substances found in many foods. Although the body normally eliminates uric acid through the kidneys, excess uric acid in the blood can accumulate and lead to a condition called hyperuricemia. Hyperuricemia is associated with a range of medical conditions, including gout, hypertension, and CKD. The Benefits of Febuxostat Febuxostat is a medication that inhibits the production of uric acid in the body. By reducing the amount of uric acid in the bloodstream, febuxostat can decrease the risk of many of the complications associated with CKD, including heart disease and stroke. In addition, there is evidence that febuxostat can slow the progression of CKD itself, in turn reducing the risk for kidney complications. Clinical trials and Studies Clinical trials have been conducted that suggest that febuxostat is a promising treatment option for late-stage CKD patients. In a study of 215 patients with late-stage CKD and hyperuricemia, patients who were treated with febuxostat were found to have significantly reduced rates of CKD progression, as well as lower rates of cardiovascular events. Other studies have suggested that febuxostat can reduce the risk of kidney stones and improve endothelial function, which is associated with better cardiovascular health. Side Effects As with any medication, there are potential side effects associated with the use of febuxostat. These side effects may include nausea, diarrhea, and headache. In rare cases, more serious side effects may occur, including liver damage, pancreatitis, and anaphylaxis. Patients considering febuxostat should talk to their physician and carefully weigh the risks and benefits before beginning this treatment. Conclusion Late-stage CKD is a serious condition that requires careful management to minimize the risk of life-threatening complications. Febuxostat, a medication that blocks the production of uric acid, has emerged as a promising treatment option for these patients. By reducing the amount of uric acid in the bloodstream, febuxostat can decrease the risk of many of the complications associated with CKD, including heart disease and stroke. However, as with any medication, it is important to carefully weigh the risks and benefits of febuxostat before beginning this treatment. Patients with late-stage CKD who are considering febuxostat should discuss this option with their physician to determine whether it is appropriate for their individual situation. #HEALTH Read the full article

[nursingscience]

Can anyone explain me about sinusitis and septum deviation and severe allergy

1. Sinusitis: Sinusitis refers to the inflammation or infection of the sinuses, which are air-filled cavities located in the skull. The sinuses are connected to the nasal passages, and their function is to produce mucus that helps moisturize and filter the air we breathe.

When the sinuses become inflamed or infected, they can cause symptoms such as:

▪️Facial pain or pressure, particularly around the forehead, cheeks, and eyes

▪️Nasal congestion or stuffiness

▪️Thick nasal discharge or postnasal drip

▪️Headache

▪️Reduced sense of smell

▪️Cough

▪️Fatigue

Sinusitis can be acute, lasting less than four weeks, or chronic, persisting for more than 12 weeks. It can be caused by a viral or bacterial infection, allergies, structural abnormalities in the nasal passages, or other factors.

Treatment options for sinusitis may include:

▪️Over-the-counter pain relievers to alleviate facial pain or headache

▪️Nasal decongestant sprays or saline rinses to reduce nasal congestion

▪️Antibiotics if a bacterial infection is present

▪️Allergy medications if allergies are contributing to the symptoms

▪️Warm compresses or steam inhalation to relieve facial pressure

In severe or recurrent cases, referral to an otolaryngologist (ear, nose, and throat specialist) for further evaluation and potential intervention.

2. Septum deviation: The nasal septum is the wall of cartilage and bone that separates the left and right nasal passages. In some individuals, the septum may be deviated, meaning it is shifted or crooked, which can affect the airflow through the nose. Septum deviation can be present from birth or result from trauma or injury to the nose.

Common symptoms of septum deviation include:

▪️Nasal congestion, often worse on one side

▪️Difficulty breathing through one or both nostrils

▪️Recurrent sinus infections

▪️Frequent nosebleeds

▪️Snoring or sleep disturbances

Treatment for septum deviation depends on the severity of symptoms. In mild cases, over-the-counter decongestants or nasal sprays may help alleviate congestion. However, if symptoms are more severe or significantly impact daily life, a referral to an otolaryngologist may be necessary.

Surgical intervention, known as a septoplasty, may be recommended to straighten the nasal septum and improve airflow.

3. Severe allergy: Severe allergies, also known as anaphylaxis, are life-threatening allergic reactions that can occur rapidly and require immediate medical attention. Allergies are the result of an overreaction of the immune system to a substance (allergen) that is typically harmless to others. Common triggers of severe allergies include certain foods, insect stings, medications, and latex.

Symptoms of severe allergies can include:

▪️Difficulty breathing or wheezing

▪️Swelling of the face, lips, tongue, or throat

▪️Rapid heartbeat

▪️Dizziness or fainting

▪️Hives or widespread itching

▪️Abdominal pain, nausea, or vomiting

▪️Anaphylaxis is a medical emergency, and prompt administration of epinephrine (adrenaline) via an auto-injector (such as an EpiPen) is the first-line treatment.

Emergency medical services should be called immediately after using the epinephrine auto-injector. Following initial treatment, further medical evaluation and monitoring are necessary.

✔️ Remedies

1. Sinusitis Remedies:

▪️Nasal irrigation: Using a saline solution or a neti pot to flush out the sinuses can help reduce congestion and improve sinus drainage.

▪️Steam inhalation: Breathing in steam from a hot shower or using a humidifier can help moisturize the nasal passages and relieve sinus pressure.

▪️Warm compress: Placing a warm compress over the sinuses can help reduce pain and promote drainage.

▪️Hydration: Drinking plenty of fluids can help thin the mucus and promote proper drainage.

▪️Rest: Getting adequate rest can support your body's healing process and boost your immune system.

2. Over-the-counter pain relievers:

Non-prescription pain relievers such as acetaminophen or ibuprofen may help alleviate facial pain and headache. Follow the instructions and consult a healthcare professional if needed.

3. Septum Deviation Remedies:

▪️Nasal decongestants: Over-the-counter nasal decongestant sprays or drops can help temporarily relieve nasal congestion. However, prolonged use can worsen symptoms, so it's important to follow the instructions and consult with a healthcare professional.

▪️Nasal strips: Nasal strips can be applied externally to the nose to help widen the nasal passages and improve airflow.

▪️Saline nasal sprays: Regular use of saline nasal sprays can help moisturize the nasal passages and reduce congestion.

▪️Avoid allergens and irritants: Minimize exposure to allergens and irritants that may worsen symptoms, such as dust, pollen, and strong odors.

4. Humidification: Using a humidifier or vaporizer can add moisture to the air, which can help reduce nasal dryness and congestion.

Severe Allergy Remedies:

▪️Epinephrine auto-injector: If you have a known severe allergy, always carry an epinephrine auto-injector (such as an EpiPen) as prescribed by your healthcare professional. In case of an allergic reaction, promptly use the auto-injector and seek immediate medical attention.

▪️Antihistamines: Over-the-counter or prescription antihistamines can help reduce allergy symptoms such as itching, sneezing, and runny nose. Follow the instructions and consult a healthcare professional for appropriate usage.

▪️Allergen avoidance: Identify and avoid triggers that cause severe allergic reactions. This may involve dietary changes, avoiding specific medications, or taking precautions with insect stings.

▪️Allergy shots (immunotherapy): For severe allergies that cannot be effectively managed with medications, allergy shots may be recommended. This involves regular injections of small amounts of allergens to desensitize the immune system over time.

Remember, these remedies are general suggestions and may vary depending on the severity and underlying cause of your symptoms. It's essential to consult with a healthcare professional for a proper diagnosis and to discuss the most suitable remedies and treatment options for your specific condition.

[coldsore-sound]

[LIVE at NOISE TRAFFIC '23]

[LIVE at NOISE TRAFFIC '23] by COLSORE

GRM performed as COLDSORE with an array of their self build METSÄÄN MACHINES, mostly the Musique Concrète Platform (bowed, plugged, stroked and scratched), Dirty Drone synth, ANAPHYLAXIS filter + some EHX pedals. Beware: This is the most 'dark ambient' recording of COLDSORE this far. Before the instrumental set, GRM made a short rather abstract vocal intro about noise, traffic, communication, transparency, responsibility, disruption of deeply engraved patterns of social behavior and complicity. Then asked the audience to talk more about normalisation + disruption! #ENDwhitesupremacy

[3liza]

im having so much trouble keeping track of everything im seriously considering just typing up a comprehensive outline-type document of all symptoms, observations, confirmed allergies, events i can remember, drugs tried and their effects, etc on my actual website so i can send people there if they ask questions or have suggestions and are trying to help or just understand whats going on.

also its really boring to keep posting it here. its boring but i have to pay attention to it all the time, every day, no matter what and its so so so boring. i have had several cycles recently this year of "feeling okay for a few days followed by a month of severe relapse" and im not exerting myself on the good days at all.

im the Patterns Noticer and i still cant identify any connection between anything i'm doing now and the apparent repercussions of my actions.

im not getting food poisoning, i can cook well enough to avoid it and understand food safety/meat temperatures/spoilage/bacteria. i dont think it's environmental unless theres some undetectable poison gas or dust or something, im not having severe allergy symptoms like anaphylaxis or hives. i have a carbon monoxide detector in working order, two actually. my house is too drafty to have an oxygen shortage. the heat is gas but i dont smell a gas leak, the boilers are separated by a concrete wall, and again this place is very drafty, especially now that it's summer.

i dont think i poisoned myself with vitamin b shots, i didnt take enough and the symptoms dont match up and i was just as bad as i am now in the same way before i took the shots. the days after i took the shots i felt way better actually.

it could be MS. it's actually really weird they havent already tested me for this. i have almost every single symptom, but MS symptoms are almost all extremely vague. i will bring this up to a doctor

it could be delayed effects from traumatic brain injury and hypoxic brain injury from earlier in life.

i dont think im bleeding internally from ulceration, my poop doesnt look bloody.

i could be short on The Vitamin or All Vitamins, this is a strong contender for "gradually worsening symptoms over several years" and having Fucked Up Stomach Syndrome can prevent you from getting the Vitamin via pills or food. it's possible that i am so low on Vitamin that i need it injected or infused. planning to follow up with this possibility

i could have poisoned myself with something else and i just cant figure out what it is. im not handling weird chemicals or eating weird stuff. nothing particularly toxic is stored here as far as im aware. i havent even painted my nails for a long time. i think the tapwater is bad here, i need to rule it out with an actual lead and heavy metals test, but i have a filter that everyone swears is capable of filtering lead.

it could be long covid. long covid has unpredictable pathology and often doesnt get Super Bad until a long time after the initial illness.

its definitely possible that "eating anything at all" is now irritating enough to my immune system (or whatever is being injured/activated) to cause a crash. this would be pretty bad, but if thats what's happening i'd like to know so i can move on to finding solutions to not eating food. fasting seems to help BUT the malnutrition symptoms kick in really fast these days, and not because i'm emaciated, im not, im regular underweight like usual with adequate fat and muscle to function normally under normal circumstances, but i think im just so sick that any additional stress is not tolerable the way it would be otherwise.

the house is definitely in mild bad shape from long term illness but its not hoarded/dangerous, there are no spills/rotten food/accumulated dirt/pests in here other than i see a couple mosquitos fly in when i let the dog on the patio. there's no garbage except the normal one bag of kitchen trash under the sink, which i take out regularly because i walk the dog 2x day. no ants, maggots, fruit flies, houseflies, silverfish other than a couple in the bathtub once in a while, no carpet beetles, couple moths once in a while. there are no piles of newspaper. i cant find any toxic materials, leaking containers, mold, asbestos, or anything along those lines. i dont smell mold, no one else who has been in here has smelled or seen mold. mold is pretty good at hiding, i guess i could run my dehumidifier and see if i improve over a week. its 55% humidity in here which is in the normal range and not damp.

the neighbors are not and have never been sick with anything environmental here, dont report any mold, and seem completely fine except when they get covid.

it could definitely be somatic illness from accumulated trauma. the partner i kicked out this year assaulted me. this stuff is completely possible to get very physically sick from with no other causes or justifications, but im not more depressed than baseline, not having nightmares, not struggling with abnormal intrusive thoughts, i just dont have any symptoms of trauma processing right now, and im extremely familiar with that stuff at this point.

one of my usual medications could be fucking me up somehow but i dont see any signs that that's the case either.

im still sick. all signs point to ongoing reactivation of latent virus (idk which one, one of the usual ones). ive been taking the antivirals and theyre not fixing me. it's not covid. i felt bett for a few days but im not sure why. dont think its any kind of food poisoning or toxicity

[comprehensive-ent-centre]

Allergies, triggered by the immune system's response to foreign substances known as allergens, manifest in various forms, impacting individuals throughout their lives. These allergens can be inhaled, ingested, or come into contact with the skin, leading to diverse symptoms. Seasonal allergies, food allergies, skin allergies, and drug allergies each present unique challenges, ranging from sneezing and runny nose to severe reactions like anaphylaxis.

Managing allergies involves understanding and avoiding triggers, with treatment options including medications, immunotherapy, and lifestyle modifications. Medications, available in various forms, help alleviate symptoms by reducing the immune response. Immunotherapy, known as allergy shot therapy, is recommended for severe or unresponsive allergies, involving a series of allergen extract injections over a period.

Home remedies and lifestyle adjustments complement medical interventions in allergy management. Identifying and avoiding allergens, using saline nasal irrigation, employing HEPA filters, and practicing good hygiene are among the suggested strategies. Essential oils, closed windows, and wearing masks provide additional relief and protection. Staying hydrated and practicing regular sinus rinsing contribute to symptom relief.

While a combination of home remedies and medications is effective for mild to moderate allergies, severe cases necessitate immediate medical attention. Consulting with healthcare professionals, particularly ENT specialists, ensures personalized guidance for comprehensive allergy management. The key lies in understanding one's unique allergic triggers and adopting a holistic approach, combining medical advice with proactive lifestyle adjustments to achieve optimal relief and a better quality of life.

[flyonthewallmedstudent]

Hydatid Cysts & Echinococcosis

Parasites are fun.

It's a tapeworm that forms cysts.

Cold open with a very short case report

30F in Mexico presents with RUQ pain and nausea

on examination of her abdo, authors felt a RUQ mass

She received an MRI of her abdo, revealing a cystic mass

on histopatho following a cystectomy, they found Echinococcosis cysts, she also had positive IgG serology to echinococcosis granulosus

Microbiology

a tapeworm that forms cysts that are usually found in the liver or lungs (if not filtered out by the liver), rarely found elsewhere but possible (numerous case reports out there reported in the brain, bones, spleen, kidneys, muscles etc.)

in humans, these cysts can remain in a person's body for years, causing no harm and no symptoms

they can grow by 1 cm per year in the liver

Cyst image from wiki

The tapeworm itself is incredibly eerie to look out, as per CDC website:

4 species of concern in people:

E. granulosus = cystic echinococcosis, or hydatid cysts

E mlutilocularis = alveolar

E. vogeli & oligarthrus = polycystic

Hosts:

generally dogs

intermediates: sheep, goats, pigs

humans are 'incidental or accidental hosts" via contact with a reservoir animal - that is to say, the parasite relies on the above 2 hosts for it's life cycle (not necessarily humans)

transmission: faecal oral, ingestion of eggs in from host faeces

larvae from the eggs penetrate the intestine and is transported in blood/lymphatics to liver (and if through liver to lungs), sometimes other organs

cysts = layers with a fibrous capsule, daughter cysts can bud off, can grow up to multiple litres and can septate and have daughter cysts over time, so may not remain unilocular. hosts may develop a granulomatous reaction

Clinical presentation

can be asymptoamtic for decades, as per 1 case report in a South Korean journal, cysts in one patient caused no issues for 30-40 years (after exposure during the Vietnam war)

become symptomatic when large enough to cause them (if in liver = nausea, vomiting, RUQ pain as per the case report, on exam: abdo distension, palpable mass and hepatomegaly, obstructive jaundice)

in cystic liver disease, it's considered a hydatid cyst and usually assiocaited with cystic echinococcosis

cysts can also eventually rupture and the fluid can cause extreme reactions such as anaphylaxis (IgE mediated Type 1 hypersensitivity reaction), leaking into the peritoneum = hydatidosis

65%: liver, 25% lungs, but 20-40% of patients can have multiorgan involvement

often acquired in childhood but present later in life (excpetion: eye and brain)

in lung: SOB, chest pain, chronic cough, haemoptysis

Rare (from stat pearls)

heart: tamponade

brain = raised ICP, seizures

spinal cord = compression

kidneys = haematuria, flank pain

bones = pathologic fractures

INcreased risk

a/w endemic areas - South America (as per case report above), former soviet union (kinda random), middle east, eastern med, Western China (I suppose these areas are all geographically connected), but also East Africa and Australia

however, alveolar echinococcosis is endemic only to Russia, China, North America and Europe

rural/grazing areas (not surprisingly given the hosts are dogs and sheep), communities needing dogs for herding

30-40 yos more likely to have hydatid cysts while > 50 are a/w alveolar

elderly and immunocompromised are more vulnerable

look for these RFs above (esp contact with dogs + cattle)

Investigations

imaging is definitive, look for the cysts, pretty big if symptomatic

nonspecific, but clues on bloods: mild eosinophilia, leukopaenia and thrombocytopaenia, deranged LFTs in hydatid cysts (abnormal in only 40% of patients, ALP usually high the rest can be normal)

imaging: USS, CT are sufficient, MRI great but no real advantage over CT, useful in the seronegative

serology is useful both in diagnosis and in follow-up after treatment, but many do not have an immune response depending on cyst wall intactness

avoids: aspiration, unless USS/CT guided given the risk of the fluid causing anaphylaxis

in the event the biliary tree is affected, await an ERCP

Stages determine management

WHO informal working group stages (IWGE) based on USS:

CE 1: simple cyst, double line sign

CE2: mlutiseptated, honeycomb/rosette

CE3A: watery lily sign - fluid collection with a detached membrane

CE3B: daughter cysts ina. solid matrix

CE4: heterogenous, hyperechoic, matrix, no duaghter cysts

CE5: solid cystic wall

1&2: active, 3 = transitional (cyst compromised), 4 and 5= inactive

ring like calcifications can be present in all stages

CT over USS = complications, like rupture, infection and biliary/vascular involvement

Treatment

albendazole - antiparasite medication is the foundation

generally depends on the size and number of cysts and there's whole WHO staging and guidelines for this

medical therapy can be anywhere from 1-3 months up to 6, but are futile if the sole treatment cysts > 5 cm or daughter cysts involved

Stage 4&5: watch and wait, USS regularly, these are uncomplicated

CE1 and CE3a: cysts < 5 cm in liver and lung, but inoperable and >2 organs involved = albendazole (CI: pregnancy and cysts vulnerable to rupture), also used following surgery and perc drainage (CT/USS guided) to prevent recurrence

surgery in: complicated cysts for removal of large stage 2 and 3b cysts or cysts that can rupture (superficial), infected, biliary tree communication and pressure on organ. Inovlves excision of cyst and possibly liver resection, contamination with daughter cysts is possible so adj albendazole and praziquantel often done (i.e. 1-4 weeks prior then 4 weeks post. has lower recurrence rates

PAIR = puncture, aspiration, inj with 20% hypertonic saline and re aspiration = USS guided in the inoperable or relapsing cases or failing to respond. usually in cysts > 5 cm with albendazole for 4 weeks, stage 1 only/single compartment cysts (PAIR ineffective in higher stages = multiple compartments)

post treatment: USS 3-6 monthly then yearly

lungs: 2 years of treatment and surgery, simple cysts may just require medical therapy

Differentials

straight from stat pearls - abscess, simple benign cysts, budd chiari, biliary colic, cirrhosis, TB, carcinoma, haemagiomas

Sources:

wikipaedia

statpearls

CDC guidelines

WHO

Australian guidelines (behind a paywall)

[sea-salted-wolverine]

So, yes, "just go get allergy shots" is glib but but expecting a significant other to accommodate you goes both ways and in this situation specifically pet allergies are pretty self selecting.

A severe dander allergy doesn't require the animal to be there to set off an reaction. If a prospective date is allergic to cats there's a solid chance they're allergic to me and an allergic reaction tends to put a damper on the romance aspect and inhibits the moving in process. Like you said, anaphylaxis is traumatic, and if your future soulmate sent you into reactions because they snuggled their pet prior to hanging out with you, you would be disinclined to hang out again.

The "i have pets" conversation is a first date kind of thing. So is the "im allergic to cats" convo, usually in response to the first one. If you've gotten to the point of moving in and you somehow missed that, what else did you miss? Even if you somehow got to moving in without mentioning animals, are you moving in sight unseen, or did you not notice the animals and associated reactions while you were there?

Not to mention, there's accommodations that can be made without ditching the pets. Areas of the home that are off limits to animals, more stringent grooming, air filters, even contamination protocols, like changing clothes after contact are all options that I have seen work for people and their partners with milder reactions and higher thresholds. In most climates a big dog can live primarily outside if it has the space and the shelter and that can solve a large portion of the issue right there. Having someone deliver an ultimatum between them and the animal that you care for and that depends on you for everything, without even considering those options is actually beyond a red flag. Especially because in the situation described, the pets predate the partner.

If your lives don't mesh as well as you hoped they might, that's a bummer. But if it is as foundational as "I enjoy having animals in my life" and "it is unhealthy for me to have animals in my life" perhaps you aren't as well suited as you thought you were.

Out of curiosity...