#Stanley Perlmutter

[nmrosario]

Mutt checks to make sure his dog, Junkyard, isn’t getting into trouble just before heading into the men’s shower tent.

I’m just working on drawing a non-superhuman male physique. However, I think members of GI Joe would all be extremely physically fit, so peak natural male fitness is what I’m trying to depict here.

[asian-heart-92]

A Real American Hero fancast (part 15)

Dylan Baker as Dr. Venom

Josh Brolin as Stanley R. Perlmutter/Mutt

Jeffrey C. Robinson as Timothy P Hanrahan/Blowtorch

Jon Bernthal as my choice #1 for Machete

Paul Logan as my choice #2 for Machete

Eugene Brave Rock as Jesse Kwinn

Zack Ward as Elwood G. Indiana/Crankcase

Carter Jenkins as Leonard Michaels/Scoop

Dave Annable as Peter R. Millman/Spearhead

Kevin Durand as Overkill

[itunesbooks]

Summary of NY Times Best Sellers 2015 - Instaread

Summary of NY Times Best Sellers 2015 Instaread Genre: Study Aids Price: $6.99 Publish Date: July 15, 2015 Publisher: Instaread Seller: Instaread Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life http://dlvr.it/R1rGpP

[jewsome]

The 49 books posted on JewishBookWorld.org in August 2020

Here is the list of the 55 books that I posted on JewishBookWorld.org in August 2020. The image above contains some of the covers. The bold links take you to the book’s page on Amazon; the “on this site” links to the book’s page on this site.

The Art of the Jewish Family: A History of Women in Early New York in Five Objects by Laura Arnold Leibman (on this site)

At the Last Moment : The Jewish Struggle for Emigration from Poland before the Holocaust by Irith Cherniavsky (on this site)

Backyard Kitchen: The Main Course by Sarina Roffe (on this site)

A Child of the Century by Ben Hecht (on this site)

Digging Up Armageddon: The Search for the Lost City of Solomon by Eric H. Cline (on this site)

European Genizah; by Andreas Lehnardt (on this site)

Faith And Courage: Plus: Del Monte And The Pocketknife by Meir Marcus Lehmann (on this site)

The fate of the Jews of Rzeszow 1939-1944. Chronicle of those days by Francis Kotula (on this site)

Fing’s War by Benny Lindelauf (on this site)

Florence Adler Swims Forever by Rachel Beanland (on this site)

Full Bloom: A Novel of Food, Family, and Freaking by Judith Arnold (on this site)

The Full Pomegranate: Poems of Avrom Sutzkever by Avrom Sutzkever (on this site)

The Ghost in Apartment by Denis Markell (on this site)

The Hidden by Mary Chamberlain (on this site)

Hip Set by Michael Fertik (on this site)

The Invention of the Jewish People by Shlomo Sand (on this site)

The Jewish Calendar Controversy of 921/2 CE by Sacha Stern (on this site)

The Jewish Ethic of Personal Responsibility Volume 2: Vayikra, Bamidbar, Devarim by Rabbi Steven Pruzansky (on this site)

Jewish Folk Tales in Britain and Ireland by Liz Berg (on this site)

The Jewish Journey Haggadah: Connecting the Generations by Adena Berkowitz (on this site)

Ladder of Light: Parashah Insights on Sefer Bamidbar by Rabbi Yaakov Hillel (on this site)

The Last Kings of Shanghai: The Rival Jewish Dynasties That Helped Create Modern China by Jonathan Kaufman (on this site)

Latkes of Love by Sara Marks (on this site)

LifeLines 3 Ordinary People; ¦Facing Extraordinary Challenges. Their Stories – and the Stories Behind Their Stories by C. Saphir (on this site)

Lives Reclaimed: A Story of Rescue and Resistance in Nazi Germany by Mark Roseman (on this site)

Lot Six by David Adjmi (on this site)

The Misadventures of Rabbi Kibbitz and Mrs. Chaipul: a midwinter romance of laughter and smiles by Mark Binder (on this site)

The New Jewish Canon by Yehuda Kurtzer, Claire E. Sufrin (on this site)

Now for Something Sweet by Monday Morning Cooking Club (on this site)

Of Bitter Herbs and Sweet Confections by Susan Shalev (on this site)

Opening Your Heart with Psalm 27: A Spiritual Practice for the Jewish New Year by Rabbi Debra J. Robbins (on this site)

Our Man in Jerusalem by Rabbi Nachman Seltzer (on this site)

The Patrons and Their Poor: Jewish Community and Public Charity in Early Modern Germany by Debra Kaplan (on this site)

Political Survivors: The Resistance, the Cold War, and the Fight against Concentration Camps after 1945 by Emma Kuby (on this site)

Return to the Reich: A Holocaust Refugee’s Secret Mission to Defeat the Nazis by Eric Lichtblau (on this site)

Social Stratification of the Jewish Population of Roman Palestine in the Period of the Mishnah, 70-250 CE by Ben Zion Rosenfeld and Haim Perlmutter (on this site)

Spinoza’s Challenge to Jewish Thought: Writings on His Life, Philosophy, and Legacy by Daniel B. Schwartz (on this site)

Stanley Kubrick: American Filmmaker by David Mikics (on this site)

The Survivors: A Story of War, Inheritance, and Healing by Adam Frankel (on this site)

A Sweet Meeting on Mimouna Night by Allison Ofanansky (on this site)

Sweet Noise: Love in Wartime by Max Hirshfeld (on this site)

The Takeaway Men by Meryl Ain (on this site)

There Was a Young Rabbi: A Hanukkah Tale by Suzanne Wolfe (on this site)

Thinking about God; Jewish Views by Rabbi Kari H. Tuling (on this site)

The War of Return by Adi Schwartz and Einat Wilf (on this site)

What I Wish My Christian Friends Knew about Judaism by Robert Schoen (on this site)

Who Really Was the Biblical Elijah? by Israel Drazin (on this site)

Winning Every Moment. Soul Conversations with the Baal HaTanya by Dr. Yehiel Harari (on this site)

Worse and Worse on Noah’s Ark by Leslie Kimmelman (on this site)

The post The 49 books posted on JewishBookWorld.org in August 2020 appeared first on Jewish Book World.

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[mariebenz]

Novel Subtypes in B Progenitor Acute Lymphoblastic Leukemia

MedicalResearch.comInterview with:

Zhaohui Gu, PhD Postdoctoral Research Associate  St. Jude Children's Research Hospital, TN MedicalResearch.com:  What is the background for this study?  What are the main findings? Response:B-progenitor acute lymphoblastic leukemia (B-ALL) is the most common pediatric malignancy and the leading cause of childhood cancer death. B-ALL includes multiple subtypes that are defined by distinct genetic alterations and that play an important role in diagnosis, prognosis and therapy of patients.  Advances in transcriptome sequencing (RNA-seq)have helped researchers discover additional subtypes and driver mutations inB-ALL and identify possible new therapeutic targets.  Still, up to 30% of B-ALL cases do not fit into established subtypes. These patients lack targeted therapeutic approaches and commonly relapse. Fort his study, we used integrated genomic analysis of 1,988 childhood and adult cases to revise the classification system of B-ALL. The system includes eight new subtypes and a total of 23 B-ALL subtypes. The subtypes are defined by chromosomal rearrangements, sequence mutations, or heterogeneous genomic alterations. Many show a marked variation in prevalence according to age. The newly identified subtypes included one (n=18) defined by rearrangements of gene BCL2, MYC and/or BCL6 anda distinctive gene expression profile (GEP). Patients in this subtype were mostly adults (n=16) with very poor outcomes. Another novel subtype was defined by IKZF1 N159Y missense mutation. N159Y is in the DNA-binding domain of IKZF1, and is known to disrupt IKZF1 function, with distinct nuclear mis-localization and induction of aberrant intercellular adhesion. There were eight cases in this subtype that shared highly similar GEPs. We also identified two subtypes with distinct GEP and characterized by PAX5 alterations. One, PAX5 altered (PAX5alt), included 148 cases. PAX5alt was characterized by diverse PAX5 alterations including rearrangements (n=57), sequence mutations (n=46) and/or focal intragenic amplifications (n=8). These PAX5 alterations were found in 73.6% of PAX5alt cases. The second distinct subtype comprised 44 cases, all with PAX5 P80R missense mutations. Bi-allelic PAX5 alterations were commonly seen in this subtype in the form of PAX5 P80R coupled with a second sequence mutation or deletion of the wild-type PAX5 allele. Adult PAX5 P80R cases showed better 5-year OS (61.9±13.4%) than those in PAX5alt subtype (42.1±10.2%). In addition, Pax5 P80R heterozygous and homozygous mice developed B lineage leukemia with a median latency of 166 and 87 days, respectively.  The heterozygous mice acquired alterations on the second allele, which faithfully recapitulated the condition of the patient leukemia. MedicalResearch.com: What should readers take away from your report? Response: Identification of subtypes accurately is very important for diagnosis, intensity-tailored therapy, and to identify targetable lesions. In this large scale genomic study, we demonstrated the power of using RNA-seq to classifying B-ALL and established a revised B-ALL taxonomy with 23 distinct subtypes. We identified 8 novel subtypes, including two defined by PAX5 alterations. Through in vitro and in vivo experiments, we demonstrated that PAX5 P80R could impair B cell differentiation and initiate leukemia. Together with the subtype defined by IKZF1 N159Y mutation, we showed for the first time that transcription factor missense mutations could be a subtype defining genetic lesions. MedicalResearch.com: What recommendations do you have for future research as a result of this work? Response:B-ALL classification has been conventionally used in scientific research and clinicaltreatment. However, due to the complexity of genetic alterations and geneexpression profile analysis, a comprehensive and robust classification is stillchallenging for many researchers and clinicians. This study establishes anRNA-seq data based B-ALL classification pipeline, which could assign over 90%of the B-ALL cases into distinct subtypes. The raw sequence data and well-curatedgenetic information of 1,988 B-ALL case have been deposited to public database(https://www.ebi.ac.uk/ega/). The dataare also accessible through an interactive St. Jude data portal (https://pecan.stjude.cloud/proteinpaint/study/PanALL),which serve as invaluable resource for future research and clinical diagnosis. We have identified eight new subtypes in previously uncategorized B-other cases. We described each subtypes’ gene expression signatures, driver genetic lesions and clinical outcomes, but in-depth functional studies and development of customized treatments for the novel subtypes are still needed. The genetic background of patients in each subtype is similar, making it easier to evaluate and compare patients’ response to specific treatments. That should potentially speed-up the development of more effective treatment for these previously uncategorized cases. Despite the progress, about 6% of the B-ALL cases still cannot be classified into any subtypes. We propose to perform more comprehensive genomic analysis, including whole genome sequence, to identify the hidden driver lesions. Ultimately, the goal is to classify all B-ALL patients into distinct subtypes and assign customized regimens for them. MedicalResearch.com: Is there anything else you would like to add? Response: This was an international effort and multiple institutional collaborative project. The participants were St. Jude Children’s Research Hospital, The Children's Oncology Group, ECOG-ACRIN Cancer Research Group, Cancer and Leukemia Group B, M.D. Anderson Cancer Center, University of Toronto, Northern Italian Leukemia Group, Southwestern Oncology Group, Medical Research Council UK and City of Hope. Citation: Abstract presented at the 2018 ASH abstract Publication Number: 565                                                             Submission ID: 111219 Title: Characterization of Novel Subtypes in B Progenitor Acute Lymphoblastic Leukemia Zhaohui Gu, PhD1, Michelle L. Churchman, PhD1, Kathryn G. Roberts, PhD1, Ian Moore, MS1, Xin Zhou, PhD2, Joy Nakitandwe, PhD1, Kohei Hagiwara, MD2, Stephane Pelletier, PhD3, Sebastien Gingras, PhD4, Hartmut Berns, PhD5, Debbie Payne-Turner, BS1, Ashley Hill, BS1, Ilaria Iacobucci, PhD1, Lei Shi, PhD6, Stanley Pounds, PhD6, Cheng Cheng, PhD6, Deqing Pei, MS6, Chunxu Qu, PhD1, Meenakshi Devidas, PhD7, Yunfeng Dai, MS7, Shalini C. Reshmi, PhD8, Julie Gastier-Foster, PhD8, Elizabeth A. Raetz, MD9, Michael J. Borowitz, MD, PhD10, Brent L. Wood, MD, PhD11, William L. Carroll, MD12, Patrick A. Zweidler-McKay, MD, PhD13, Karen R. Rabin, MD, PhD14, Leonard A. Mattano, MD15,Kelly W. Maloney, MD16, Alessandro Rambaldi, MD17, Orietta Spinelli, PhD17, Jerald P. Radich, MD18, Mark D. Minden, MD, PhD19, Jacob M. Rowe, MD20, Selina Luger, MD21, Mark R. Litzow, MD22, Martin S. Tallman, MD23, Janis Racevskis, PhD24, Yanming Zhang, MD25, Ravi Bhatia, MD26, Jessica Kohlschmidt, PhD27, Krzysztof Mrózek, MD, PhD27, Clara D. Bloomfield, MD27, Wendy Stock, MD28, Steven Kornblau, MD29, Hagop M. Kantarjian, MD29, Marina Konopleva, MD29, Williams Evans, PharMD30, Sima Jeha, MD31, Ching-Hon Pui, MD31, Jun Yang, PhD30, Elisabeth Paietta, PhD24, James Downing, MD1, Mary V. Relling, PharMD30, Jinghui Zhang, PhD2, Mignon L. Loh, MD32, Stephen P. Hunger, MD33, Charles Mullighan, MBBS, MD1 1Department of Pathology, St. Jude Children’s Research Hospital, Memphis, TN 2Department of Computational Biology, St. Jude Children’s Research Hospital, Memphis, TN 3Department of Immunology, St. Jude Children’s Research Hospital, Memphis, TN 4Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261 5Department of Transgenic Core Facility, St. Jude Children’s Research Hospital, Memphis, TN 6Department of Biostatistics, St. Jude Children’s Research Hospital, Memphis, TN 7Department of Biostatistics, University of Florida, Gainesville, FL 8Institute for Genomic Medicine, Nationwide Children’s Hospital, Columbus, OH 9Division of Pediatric Hematology-Oncology, New York University, New York, NY 10016, 10Division of Hematologic Pathology, Johns Hopkins University, Baltimore, MD 11Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA 12Perlmutter Cancer Center, NYU-Langone Health, New York, NY 13ImmunoGen, Inc, Waltham, Massachusetts 14Baylor College of Medicine, Houston, TX 15HARP Pharma Consulting, Mystic, CT 16University of Colorado School of Medicine and Children’s Hospital, Aurora CO 17Hematology and Bone Marrow Transplant Unit, Ospedale Papa Giovanni XXIII, Bergamo, Italy 18Fred Hutchinson Cancer Research Center, Seattle, WA  19Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada 20Hematology, Shaare Zedek Medical Center, Jerlem, Israel  21Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA 22Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN 23Memorial Sloan Kettering Cancer Center, New York, NY 24Cancer Center, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 25Cytogenetics Laboratory, Memorial Sloan Kettering Cancer Center 26Division of Hematology-Oncology, University of Birmingham, Alabama 27Comprehensive Cancer Center, The Ohio State University, Columbus, OH  28University of Chicago Medical Center, Chicago, IL  29Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX  30Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, TN 31Department of Oncology, St. Jude Children’s Research Hospital, Memphis, TN 32Department of Pediatrics, UCSF Benioff Children’s Hospital and the Helen Diller Family 33Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website. Read the full article

[sherristockman]

Popular Kind of Meat Might Lead to Mood Swings and Mental Illness Dr. Mercola By Dr. Mercola What you eat affects the way you feel, both physically and mentally, and if you're someone who enjoys snacking on beef jerky from time to time, you should take note. Beef jerky with nitrates added was linked to a host of concerning mental changes, including mania in humans and altered behavior and brain gene expression in rats.1 Beef jerky might seem like an obscure topic for a scientific study, but it's been growing in popularity in recent years. Sales of meat snacks increased 3.5 percent from 2016 to 2017 to reach nearly $3 billion in sales. That growth rate is more than twice that seen for potato chips over the same period,2 likely because snackers are increasingly looking for more health conscious, nutritious choices. Beef jerky, while far from a health food (especially in most of its commercial forms), is high in protein, making it a go-to choice for people looking to cut down on processed carbs. There are a number of reasons why you may want to rethink this "healthy" snack, however, starting with its potential effects on your mental health. Could Beef Jerky and Other Processed Meats Cause Mania? Mania is a neuropsychiatric condition that causes hyperactivity, insomnia and feelings of euphoria. It's often seen as part of mental conditions such as bipolar disorder and schizoaffective disorder, and although it may have a genetic component, environmental factors are also thought to play a role. During a manic episode, delusional thinking and risk-taking behavior may occur, leading to multiple hospitalizations. Up to 3 percent of Americans are estimated to have bipolar disorder, costing $25 billion a year in direct health care costs.3 The featured study, published in Molecular Psychiatry, reviewed health records from more than 1,000 people, some with psychiatric disorders and some without. People who were hospitalized with mania were 3.5 times more likely to have eaten cured meats than people without a history of psychiatric disorders. Study author Dr. Robert Yolken, the Theodore and Vada Stanley distinguished professor of neurovirology in pediatrics at Johns Hopkins University School of Medicine, said in a statement, "We looked at a number of different dietary exposures and cured meat really stood out … It wasn't just that people with mania have an abnormal diet."4 The researchers also fed rats meat preparations with added nitrates, namely "store-bought, nitrate-prepared beef jerky, which led to mania-like hyperactivity and irregular sleeping patterns in the animals, along with alterations in brain pathways that have been implicated in human bipolar disorder and changes in intestinal microbiota. The same results occurred when the rats were fed rat chow with nitrates added, while rats that ate nitrate-free beef jerky or rat chow with no nitrates displayed no such changes. The amount of nitrate the rats consumed was equivalent to what a human might consume by eating one beef jerky stick or hot dog daily. "Future work on this association could lead to dietary interventions to help reduce the risk of manic episodes in those who have bipolar disorder or who are otherwise vulnerable to mania," Yolken said.5 "It's clear that mania is a complex neuropsychiatric state, and that both genetic vulnerabilities and environmental factors are likely involved in the emergence and severity of bipolar disorder and associated manic episodes," says Khambadkone. "Our results suggest that nitrated cured meat could be one environmental player in mediating mania." Seva Khambadkone, of Johns Hopkins department of psychiatry and behavioral sciences, also worked on the study, adding:6 "It's clear that mania is a complex neuropsychiatric state, and that both genetic vulnerabilities and environmental factors are likely involved in the emergence and severity of bipolar disorder and associated manic episodes. Our results suggest that nitrated cured meat could be one environmental player in mediating mania." Why Might Nitrate-Laden Processed Meats Disrupt Your Mental Health? Nitrates in cured and processed meats such as beef jerky, bacon and hotdogs are known to be carcinogenic and have also been implicated in neurodegenerative diseases. The nitrates in processed meats are turned into nitrites by bacteria in your mouth, and then into carcinogenic nitrosamines when they reach your stomach.7 As explained by Gunter Kuhnle, professor of food and nutritional sciences at the University of Reading, U.K., "What makes processed meats so ideal for forming N-nitroso compounds is that they have a combination of nitrite and proteins from the meat. And the meat's heme seems to help convert them into N-nitroso compounds."8 "Nitrosamines mediate their mutagenic effects by causing DNA damage, oxidative stress, lipid peroxidation and proinflammatory cytokine activation, which lead to increased cellular degeneration and death," researchers wrote in the Journal of Alzheimer's disease.9 These same processes also contribute to neurodegeneration that could influence your mental health. Nitrosamines are also linked to inflammation, a key player in cancer and other diseases that has also been implicated in manic episodes. "We think the key is probably inflammation," Yolken said in a news release.10 Gut microbiota is another primary suspect, as the rats that ate nitrates had different bacterial strains in their guts than the other animals. "There's growing evidence that germs in the intestines can influence the brain," says Yolken. "And this work on nitrates opens the door for future studies on how that may be happening."11 Your Gut Holds a Key to Your Mental Health What you eat can make or break your gut health, which in turn plays a part in your brain health — and nitrate-rich processed meats are in the category of what NOT to eat for good gut health. Dr. David Perlmutter, author of "Brain Maker: The Power of Gut Microbes to Heal and Protect Your Brain for Life," stated: "We're now recognizing from research at our most well-respected institutions from around the globe that the gut bacteria are wielding this very powerful sword of Damocles. They determine whether we're going to have a healthy brain or not, whether our brain is going to function well or not, and whether our brain is going to become diseased or not. Who knew that we'd be referring back to the gut?" Separate research conducted by Yolken and colleagues, involving 56 people with schizophrenia, revealed that taking beneficial bacteria, or probiotics, supplements for two weeks not only significantly reduced levels of Candida yeast (which tend to be elevated in people with this disorder) in men but also led to an improvement in psychiatric symptoms.12 It's now known that your gut is connected to your brain via what's called the gut-brain axis, which means whatever affects your gastrointestinal tract affects your brain, and vice versa. As such, when your gut microbiome is unbalanced, it can affect your immune system, mental health, mood and more. Probiotics have even been shown to help reduce the symptoms of depression and alter behavior and feelings of anxiety. One small study involving adults diagnosed with irritable bowel syndrome (IBS) and depression found the probiotic Bifidobacterium longum provided depression relief.13 Another type of bacteria, lactobacillus, has been shown to reduce anxiety in animal studies,14 while taking a probiotic with eight different bacterial strains reduced aggressive and ruminative thoughts in a study of adult volunteers.15,16 Some Nitrates Are Good for You While the nitrate-laden processed meat is a health hazard, nitrates from plants are quite good for your health. Plants contain antioxidants (such as vitamin C and polyphenols) that impede the formation of harmful nitrosamines. The presence of these compounds help to ensure that the nitrates are converted into beneficial nitric oxide (NO) once they reach your stomach rather than harmful nitrosamine compounds. Most plant foods are also not cooked or fried at high temperatures, an important distinction since nitrates are also more prone to converting into carcinogenic nitrosamines when heated. Plants rich in naturally occurring nitrates, such as arugula, rhubarb and beets, are excellent dietary additions to boost NO, which in turn promotes healthy endothelial function and heart health by dilating your blood vessels, helps maintain physiological homeostasis, suppresses inflammation and promotes angiogenesis, the formation of new, healthy blood vessels. NO is also beneficial for your brain, as it boosts brain neuroplasticity by improving oxygenation of the somatomotor cortex (a brain area frequently affected in the early stages of dementia).17 If you do eat processed meats containing nitrates, having a healthy gut is still important, as research suggests beneficial bacteria help break down nitrosamines, while bad gut bacteria increase nitrosamine production.18 In other words, there appears to be a very intimate relationship between dietary nitrates and various gut bacteria. It can either work to your advantage, such as when you combine probiotics with nitrate-rich plant food, or against you, such as when you eat beef jerky or other processed meats with added nitrates. More Reasons to Ditch Processed Meats Much more remains to be discovered about the link between processed meats and mania, but there's plenty of evidence already on the table to make you think twice about eating these foods with any regularity. In fact, the American Institute for Cancer Research (AICR) has long recommended avoiding processed meats entirely and states "there is no safe threshold" for eating them.19 For instance: Eating just 1.8 ounces of processed meat per day — about one sausage or two to three slices of bacon — was found to raise your likelihood of bowel cancer by 20 percent.20 Eating just 9 grams of bacon per day significantly raises a woman's risk for breast cancer later in life.21 Eating processed meats affects male fertility; men who ate the least amount of processed meat had a 28 percent higher rate of fertilization during IVF compared to those who ate the most.22 After reviewing some 800 studies, the International Agency for Research on Cancer (IARC), which is part of the World Health Organization, concluded that processed meat can cause colorectal cancer in humans.23 In addition to the nitrates (and related nitrosamines), processed meats typically come from concentrated animal feeding operations (CAFOs) and are cooked at high temperatures, further compounding their health risks. If you choose to eat processed meat, you can somewhat minimize the hazards by choosing organic, nitrate-free varieties made with grass fed meat. To further support your physical and mental health, minimize (or eliminate) your intake of nitrates from processed meats while increasing your intake of nitrates from plant foods. Plant foods high in nitrates include arugula, rhubarb, cilantro, butter leaf lettuce, spring greens, basil, beet greens, oak leaf lettuce, Swiss chard and red beets, especially fermented beets.

[dawnlindse-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life

[evelyngra-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life

[nmrosario]

Some more G.I. Joe fan art.

Mutt takes Junkyard for a walk along the beach early on a Saturday morning. Mutt is wearing a 50-pound rucksack just so he can get some exercise out of it as well.

[estherdel-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life

[joycelow-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life

[rubywilll-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life

[meredithandre-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life

[elizabethrus-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life

[attendantdesign-blog]

New Post has been published on Attendantdesign

New Post has been published on https://attendantdesign.com/macerichs-mac-ceo-art-coppola-on-q2-2017-results/

Macerich's (MAC) CEO Art Coppola on Q2 2017 Results -

    Executives

Jean Wood – Vice President, Investor Relations

Art Coppola – Chief Executive Officer and Chairman

Tom O’Hern – Senior Executive Vice President and Chief Financial Officer

Robert Perlmutter – Senior Executive Vice President and Chief Operating Officer

John Perry – Senior Vice President, Investor Relations

Analysts

Craig Schmidt – Bank of America

Michael Bilerman – Citi

Alexander Goldfarb – Sandler O’Neill

Jim Sullivan – BTIG

Michael Mueller – JPMorgan

Todd Thomas – KeyBanc Capital Market

Vincent Chao – Deutsche Bank

Wes Golladay – RBC capital Markets

Haendel St. Juste – Mizuho

Rich Hill – Morgan Stanley

Greg McGinniss – UBS

Tayo Okusanya – Jefferies

Operator

Good day, and welcome to the Macerich Company’s

Second Quarter 2017 Earnings Conference Call. Today’s conference is being recorded. At this time, I would really like to show the conference over to Jean Wood, Vice President of Investor Relations. Please go ahead.

Jean Wood

Thank you, everyone, for becoming a member of us nowadays on our 2nd region 2017 profits name. During the route of this call, management may additionally make certain statements that perhaps deemed forward-searching inside the which means of the Safe Harbor of the Private Securities Litigation Reform Act of 1995. Actual results might also fluctuate materially due to a selection of dangers, uncertainties, and other elements. We refer you to nowadays’s press launch and our SEC filings for an in depth dialogue of ahead-looking statements. Reconciliations of non-GAAP economic measures to the most at once similar GAAP measures are covered within the income launch and supplemental filed on Form eight-K with the SEC, which is posted within the Investors phase of the employer’s internet site at www.Macerich.Com.

Joining us nowadays are Art Coppola, CEO, and Chairman; Tom O’Hern, Senior Executive Vice President and Chief Financial Officer; Robert Perlmutter, Senior Executive Vice President and Chief Operating Officer; and John Perry, Senior Vice President, Investor Relations.

With that, I would like to show the decision over to Tom.

Tom O’Hern

Thank you, Jean, and welcome all and sundry. The second CEO region Macerich’s  pondered Coppola 

persevered stable operating outcomes as evidenced by the maximum of our portfolio’s key working metrics. For the quarter, FFO changed into $zero.98 in keeping with the share as compared to $1.02 for the sector ended June 30, 2016. This was above our steering variety and above consensus and this became in general due to the timing of hire termination revenues. Same-center increase and internet working earnings, apart from straight line rents and SFAS 141 profits become up three.3% for the region. Lease termination costs for the zone had been $nine.1 million that in comparison to $five.Nine million within the 2d quarter of ultimate 12 months. The biggest time period charges came in from Bebe at $3 million and Sperry at $2 million.

Year-to-date, rent time period revenue is ready $12 million, including our steering assumptions, we revised that as much as $17 million for the year but that’s nonetheless much less than we saw in 2016 while we had actual term – lease time period revenue of about $21 million. The gross running margin for the quarter was 70.4%, up barely compared to 70.3% in the second region closing yr. Bad debt cost for the zone was $2.Five million, up incredibly from the $1.7 million we incurred in the 2nd sector of ultimate yr. Year-to-date, terrible debt expense is ready $4.2 million and for this reason, we have increased our steering for bad debt for the year to $6.Five million, up from $5 million.

Here within the 2d sector, common hobby rate become 3.6% and that as compared to a few.Fifty-two% a year in the past. Bringing out the balance sheet, the balance sheet continues to be in right form. At one end, debt-to-marketplace cap turned into forty-six%. Interest insurance ratio became a very wholesome three.3x. The average debt maturity, simply underneath 6 years, which may be very sturdy and need to improve over the route of the 12 months as we finish financings within the 2nd 1/2 of the yr. Forward debt-to-EBITDA, 7.8x, and our floating charge debt was at 17% of our total debt, however, this – based on our financing sports in the 2d 1/2, this need to go down to shut to 10% with the aid of or stop.

Installing QuickBooks Online (without the need to convert QuickBooks for Mac files to QuickBooks online files) is relatively easy and straightforward. However, it gets a bit complicated when you need to convert an existing  QuickBooks for Mac file to a  QuickBooks Online file. Intuit does a reasonably good job of facilitating the online installation.

Manually converting your QuickBooks for Mac file to QuickBooks Online

is not that difficult, as long as you carefully follow the instructions and generally takes about 30 minutes. You cannot directly convert your QuickBooks for Mac file to QuickBooks Online. There is an intermediate step that requires you to convert your QB Mac file to a QB Windows files and begins with the drop down menu in QuickBooks Mac.  The process begins, by selecting the File menu and then selecting “Back up to QuickBooks for Windows”  within the QuickBooks for Mac software. Upon completion of this process, the file is sent to QuickBooks and you receive a notification when the process for converting the QuickBooks Mac to QuickBooks Online is completed. Initially, I was surprised to observe that this process is performed at the Intuit level rather than in real time. A suggestion to facilitate this process is that in the event you do not receive timely notification of completion from Intuit, I suggest that you contact tech support and ask them to look into the status of your conversion and request that they expedite it for you. Generally, when  I have called tech support, and they are very accommodating. They will facilitate the process, although they generally do not give any time guarantee and attribute the potential delay to their busy servers.

Overall the manual conversion process takes approximately 30 minutes (exclusive of the Intuit conversion) and my clients have been happy with QBO. One client was disappointed that the vendor type classifications are not available in QuickBooks Online. The workaround for this is to use one of the fields in the vendor profile as the vendor type.  So far, my clients are happy to have multi-user access, the ability to work from anywhere and unattended and automatic backups, despite a slightly sluggish performance attributable to the web connection.

Two words of caution, the first of which is that QuickBooks Online currently does not support inventory applications and the second, that the conversion may require the services of your accountant or CPA to affect a smooth and orderly transition to the QuickBooks Online platform.

As long as you understand up front the limitations of QBO, then you should find the QBO platform acceptable and more importantly,  a helpfully financial tool to run and monitor your business.

Sandor Lenner, CPA has been providing accounting services for companies for 35 years. He is also a Certified QuickBooks ProAdvisor and provides QuickBooks support and small business accounting services while working as a part-time consultant with Susan Missal Lenner, P.A.

Our Mission Statement is to help small businesses become self-sufficient, make correct business decisions and to effectively compete with larger companies on a local, regional and global basis through the use of state of the art accounting technology and the internet.

[annerodr-blog]

New York Times Best Sellers - Instaread | Biographies & Memoirs |1020474373

New York Times Best Sellers Instaread Genre: Biographies & Memoirs Price: $6.99 Publish Date: July 15, 2015 Missed out on the New York Times Best Sellers? Get this bundle now! It has a collection of Key Takeaways & Analysis on 25 Latest Non-Fiction New York Times Best Sellers. Below is the list of books you will get in this bundle. Rising Strong: by Brene Brown | Key Takeaways, Analysis & Review Being Mortal: by Atul Gawande | A 15-minute Key Takeaways & Analysis: Medicine and What Matters in the End The Life-Changing Magic of Tidying Up: by Marie Kondo | A 15-minute Key Takeaways & Analysis: The Japanese Art of Decluttering and Organizing It IS About Islam: by Glenn Beck | Key Takeaways, Analysis & Review: Exposing the Truth About ISIS, Al Qaeda, Iran, and the Caliphate Primates of Park Avenue by Wednesday Martin: Summary & Analysis Adios, America: The Left's Plan to Turn Our Country into a Third World Hellhole by Ann Coulter: Key Takeaways, Analysis & Review Plunder and Deceit: by Mark R. Levin | Key Takeaways, Analysis & Review  Legends and Lies by Bill O'Reilly and David Fisher | Summary & Analysis: The Real West H is for Hawk by Helen Macdonald | A Review Elon Musk by Ashlee Vance | Summary & Analysis: Tesla, SpaceX, and the Quest for a Fantastic Future The Boys in the Boat by Daniel James Brown | Summary & Analysis: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics The Power of Habit: by Charles Duhigg | A 15-minute Key Takeaways & Analysis: Why We Do What We Do in Life and Business The Road to Character by David Brooks | Key Takeaways & Analysis The Wright Brothers by David McCullough | Key Takeaways & Analysis Becoming Steve Jobs by Brent Schlender and Rick Tetzeli | Summary & Analysis: The Evolution of a Reckless Upstart into a Visionary Leader Goddesses Never Age by Christiane Northrup M.D. | Key Takeaways & Analysis: The Secret Prescription for Radiance, Vitality, and Well-Being Team of Teams by General Stanley McChrystal | Key Takeaways & Analysis: New Rules of Engagement for a Complex World Zero to One by Peter Thiel - A 20-minute Instaread Summary: Notes on Startups, or How to Build the Future The Immortal Life of Henrietta Lacks: by Rebecca Skloot | A 15-minute Key Takeaways & Analysis Dead Wake: by Erik Larson | Summary & Analysis: The Last Crossing of the Lusitania Missoula by Jon Krakauer | Summary & Analysis: Rape and the Justice System in a College Town The Emperor of All Maladies by Siddhartha Mukherjee | Key Takeaways & Analysis: A Biography of Cancer Money Master the Game: by Tony Robbins | A 15-minute Key Takeaways & Analysis: 7 Simple Steps to Financial Freedom It Starts With Food: by Melissa and Dallas Hartwig | A 15-minute Key Takeaways & Analysis Brain Maker by Dr. David Perlmutter and Kristin Loberg | A Review: The Power of Gut Microbes to Heal and Protect Your Brain-for Life