#Retinoblastoma awareness

[drsurbhikapadia]

Act Now: The Importance of Early Retinoblastoma Screening

A simple flash photo could reveal more than you think. If you notice a white disk in your child's eye in flash photography, it may be a sign of retinoblastoma. Dr. Surbhi Kapadia from the Department of Ophthalmology & Ophthalmic Plastic Surgery urges parents to get their children screened today. Early detection can make all the difference in your child's eye health and overall well-being.

[cripplecharacters]

Could Persistent fetal vasculature lead to the affected eye being lost or having to be removed?

I'm trying to come up with a way a character could be born without an eye, or non-traumatically lose it as a child.

Hi,

PFV used to be a potential reason back when it was ignored until significant complications appeared later, but it wouldn't fit the "as a child" part as far as I'm aware. Generally the glaucoma etc. associated with it would develop later. You can check out "Persistent Hyperplastic Primary Vitreous" since it's the old name of the same thing and it's more associated with enucleation than "persistent fetal vasculature". If you want your character to have PFV it might help with research.

The most common reason to be born without an eye is just anophthalmia. Sometimes it has additional symptoms since there are a lot of really rare disorders that come with it, but mostly it's just not having an eye.

Other congenital causes could be thalidomide syndrome, TORCH infections, Goldenhar syndrome (rare, but it does sometimes happen), Patau syndrome (chromosomal condition that affects life span, a lot of research advised). There are of course more, but most causes are very, very rare. These are the most common ones I'm aware of.

For losing it after they were born; microphthalmia can result in removal (it can also be a stand-alone thing, or part of a syndrome, like Goldenhar), eye cancer, or eye infection. Late stage glaucoma or another cause of an eye being blind-and-painful would also be a reason for removal.

Generally for acquired childhood eye loss, retinoblastoma is probably the most common. I don't have an actual statistic, but it really feels like every other person who lost a single eye had retinoblastoma when they were two.

Hope this helps,

mod Sasza

[ganitsoni]

Understanding the Risk Factors for Secondary Cancers

Secondary cancers, also known as second primary cancers or metachronous cancers, are new, unrelated cancers that develop in individuals who have previously been diagnosed with cancer. While surviving cancer is a significant achievement, it's essential to be aware of the risk factors for secondary cancers. Let's explore what these risk factors are and how individuals can take steps to reduce their risk.

What Are Secondary Cancers?

Secondary cancers occur when new cancerous cells develop in tissues or organs unrelated to the original cancer diagnosis. These cancers are not recurrences or metastases of the original cancer but are entirely new primary cancers. For example, a person who has been successfully treated for breast cancer may develop a secondary cancer, such as lung cancer, years later.

Risk Factors for Secondary Cancers:

Previous Cancer Treatment: Certain cancer treatments, such as radiation therapy and chemotherapy, can increase the risk of developing secondary cancers. Radiation therapy exposes healthy cells to ionizing radiation, which can damage DNA and increase the likelihood of mutations that lead to cancer. Similarly, some chemotherapy drugs can cause DNA damage and increase the risk of secondary cancers.

Genetic Predisposition: Individuals with certain genetic conditions, such as Li-Fraumeni syndrome, hereditary retinoblastoma, and familial adenomatous polyposis, have an increased risk of developing multiple cancers over their lifetime. These genetic conditions can predispose individuals to the development of primary and secondary cancers.

Environmental and Lifestyle Factors: Environmental factors, such as exposure to carcinogens like tobacco smoke, asbestos, and ultraviolet radiation from the sun, can increase the risk of developing cancer. Lifestyle factors, including smoking, excessive alcohol consumption, poor diet, and lack of physical activity, can also contribute to the development of secondary cancers.

Age: The risk of developing secondary cancers tends to increase with age. As individuals live longer, they may be exposed to additional risk factors and accumulate genetic mutations that increase the likelihood of developing cancer.

Hormonal Factors: Hormonal factors, such as hormone replacement therapy (HRT) and oral contraceptive use, can influence the risk of developing certain types of secondary cancers. For example, long-term use of estrogen-only HRT has been associated with an increased risk of developing endometrial cancer.

Immune Suppression: Individuals with weakened immune systems, such as organ transplant recipients and those living with HIV/AIDS, are at an increased risk of developing secondary cancers. A compromised immune system may be less effective at detecting and eliminating cancerous cells, allowing them to proliferate and form new tumors.

Prevention and Management:

While some risk factors for secondary cancers cannot be modified, there are steps individuals can take to reduce their risk:

Follow-up Care: Regular follow-up care with healthcare providers is essential for cancer survivors. This includes routine screenings, physical examinations, and laboratory tests to detect any signs of recurrence or new cancers early.

Healthy Lifestyle Choices: Adopting a healthy lifestyle can help reduce the risk of developing secondary cancers. This includes maintaining a balanced diet rich in fruits, vegetables, and whole grains, engaging in regular physical activity, avoiding tobacco products, limiting alcohol consumption, and protecting the skin from sun exposure.

Genetic Counseling and Testing: Individuals with a family history of cancer or known genetic predispositions may benefit from genetic counseling and testing. These services can help identify individuals at increased risk of developing cancer and inform personalized screening and prevention strategies.

Minimize Environmental Exposures: Minimizing exposure to known carcinogens and environmental toxins can help reduce the risk of developing cancer. This includes avoiding tobacco smoke, limiting exposure to ultraviolet radiation from the sun, and following safety precautions in occupational settings with potential chemical exposures.

Conclusion:

While surviving cancer is a significant achievement, cancer survivors need to be aware of the risk factors for secondary cancers. Understanding these risk factors and taking proactive steps to reduce them can help individuals live healthier, longer lives. By following recommended screening guidelines, adopting a healthy lifestyle, and minimizing exposure to known carcinogens, cancer survivors can take control of their health and reduce their risk of developing secondary cancers. If you or someone you know is a cancer survivor, it's essential to discuss any concerns or questions about secondary cancer risk with a healthcare provider. With knowledge, awareness, and proactive management, individuals can minimize their risk and continue to thrive after cancer.

[backlinkdem13]

OCULAR ONCOLOGY

Ocular oncology is known as Eye Cancer and it is a rare disease. Eye cancer mainly occurs within the eye and on the surface area of the eye. The cells of the eyes get affected and the tear glands also get damaged. Many times it has been observed that other body parts’ tumours also spread to the eyes. You can face problems in vision, likewise blurry vision, and sensitivity to light. 

SYMPTOMS

The following symptoms can be seen, 

Hazy vision

Loss or reduction of eyesight

Floaters (small dots or lines in your vision)

Responsiveness to light

The pupil's shape has changed (the dark circle in the center of the eye)

iris dark spot that is growing (colored part of the eye)

Having a red or swollen eye

TYPES OF CANCER

Retinoblastoma: The cells of the retinas, the light-sensing cells at the back of the eye, are where this uncommon cancer, which is most prevalent in children under the age of five, begins. Because infants and young children often are unable to communicate if they are experiencing visual problems, retinoblastoma is particularly challenging to detect. Parents can notice their child's pupils aren't red in pictures or that they have amblyopia (lazy eye).

Squamous cell carcinoma: On the eye's surface, this form of cancer first appears.

Non-Hodgkin lymphoma:  Lymphoma is a malignancy that develops in white blood cells and can start in many locations in the eye.

If you suffer through any following symptoms, consult an eye specialist for further treatment. Eye specialists can help you to understand the issue and if it is needed then you can contact an oncologist. According to the condition of the disease, the doctor can suggest how to do the treatment with the eyes.

Doctors specialising in this field can provide intricate guidance on the cases. One should always be aware and look out for symptoms which may seem like nothing at first but can turn to worse, if ignored. 

Mentionable names among some of the Best Oncologists in Kolkata are:

Dr. Sanjoy Roy  and Dr. Sayan Paul.

[andrewmartinopt]

It's World Retinoblastoma Awareness Week.

Learn more at http://wu.to/FgCJZs http://wu.to/y2EL5f

If you see a white glow in the eye, a white pupil or white reflection in a photo where a flash has been used, or when your child is in artificial light or a darkish room, visit a healthcare professional ASAP as this is the most common sign of retinoblastoma (childhood eye cancer).

#AndrewMartinOpt #RbWeek #SightCareLocal #Boldmere #MereGreen #SuttonColdfield #WhiteEye

[manipalhospital1]

Childhood Cancers Are Curable

Every year on February 15, International Childhood Cancer Day is observed to raise awareness about childhood cancer and to support families.

Every year, three to four lakh children are diagnosed with cancer worldwide. In India, over 50,000 cases are reported each year. There is a big gap in the survival of these children between developed and developing countries. Most of these cancers can be cured if we detect them early and provide the right treatment and supportive therapy. In many parts of our country, these children are not able to receive tertiary oncology services.

Childhood Cancers are Different from Adult Cancers

We don't know why the vast majority of childhood cancers occur. The role of lifestyle and environmental factors in the development of cancer in children is limited. They are present at an advanced stage, but they respond better. Cancer types seen in children differ from those seen in adults. We see blood cancers, brain tumours, abdominal masses, and lymphomas more commonly in children. In terms of tolerance to chemotherapy, children do better than adults. Visit a top hospital for childhood cancer treatment in Mangalore as early as possible to get the best results and avoid complications.

The common question that parents and their relatives routinely ask is about the cause of cancer and how it can be prevented. Cancer develops when the cells' repair mechanisms get disturbed, leading to the uncontrolled production of bad cells.

Blood cancers are the Most Common Type of Childhood Cancer

It accounts for nearly 1/3 of all childhood cancers. To create the appropriate referral pathway, we must raise awareness among parents as well as primary care physicians. They usually present with prolonged fever, body pain, bony pain, not eating well, losing weight, skin bruises, bleeding, and small swellings in the neck. On performing a simple blood test such as the CBC, which may show low haemoglobin, a high or low white blood cell count, a higher number of lymphocytes, and low platelet counts, if we provide proper treatment, then over 80% of them can be completely cured. We can cure more than 90% of patients with other types of cancer, such as Hodgkin's lymphoma, Wilms tumour, and retinoblastoma. Consult a top blood cancer hospital for childhood cancer treatment in Mangalore.

Brain tumours can cause early morning vomiting, headaches, new-onset seizures, balance and gait problems, and changes in behaviour and handwriting.

Treatment of Childhood Cancer is Challenging

Children are supposed to be with other children during their childhood, studying in school. However, once we start treatment, they spend 2–3 years of their lives in the hospital environment. The family too suffers and finds it difficult to cope; siblings suffer due to lack of attention. They cannot go to work, as most of the time both parents stay with the sick child in the hospital.

The overall survival rate of childhood cancers in developed countries is around 80%, whereas it is around 40-50% in India. This, too, varies from centre to centre and state to state.

Previously, it was considered a death sentence when one was diagnosed with cancer, but not anymore. Childhood acute lymphoblastic leukaemia (a type of blood cancer) has been dubbed a modern medicine success story, with cure rates increasing from 30% to over 90%. The treatment lasts for 2 to 3 years. Other types of cancer require treatment for 2–12 months. With the availability of advanced pathology labs, radiology services, blood banks, radiation oncology, and good nursing care, many centres have come up in India to provide holistic treatment to children.

Consult a top oncologist in Mangalore for the diagnosis and treatment of cancers in children.

To provide high-quality service, we need to get everything right, which comes at a cost. Hence, cancer care is expensive. Fortunately, these days many NGOs, government schemes, and private donors come forward to fund needy children, which helps complete the treatment and improve the overall cure rate. In this part of coastal Karnataka, no child goes home without treatment for lack of finances.

[baytownproject]

(1 of 2) “It showed up a couple times in pictures of Maycie. Instead of red eye, she had white. Then we noticed it every once in a while when she was in the bathtub or in her high chair. We thought it was a reflection from the white of the tub or the white of her high chair tray. But then it got to where her eyes kind of seemed empty. It was really strange. So we took her to a pediatrician. She told us there was an absence of a red reflex, and that we needed to go to Texas Children’s Hospital the next day. Maycie was diagnosed with bilateral retinoblastoma, which is cancer of the retina in both eyes. She was 11 months old. I was devastated. The tumors in her right eye were not in the optic nerve yet, but they were too close. They didn’t want it to spread to her brain. So the best course of treatment was to remove the right eye and try to save the left eye. Believe it or not, it’s day surgery. Her right eye was removed on October 24, 2002, which was our fourth wedding anniversary. She came home, slept half the day, and then she was up and playing. At first, we were pretty optimistic about the other eye. For about a year and a half, we tried to save it. We did six months of chemotherapy. We did laser therapy. We did cryotherapy. She had 28 days of radiation. But in the end, we couldn’t save it. I worked at a daycare at the time. Maycie would sit up against the wall and isolate herself, not wanting to be around people. If anyone would get near her, her first instinct was to bite. So she had a little harder time after the second eye was removed. When they’re that age, though, they’re pretty resilient. She bounced back. She ended up getting prosthetic eyes. But it was hard not to keep thinking, if only we had known the signs. Those white dots in her eyes in all the pictures screamed cancer, letting us know that something was terribly wrong. We just didn’t know the signs of retinoblastoma, and we sure didn’t know she probably had it since birth. Some days, the guilt that consumes me is mentally and physically crippling. I know it’s not my fault. I know there’s no way I could have known. But that doesn’t help. What does help is knowing I have spread awareness of retinoblastoma, so that it might possibly help someone else.”

— Brandi Gonzalez

[musicalplumbob]

It has been an exhausting week. I’m not sure when I’ll be posting again, guys, but I’m trying to check in every so often. My daughter is going to have her eye cancer treated at Stanford which we are lucky to only live about three hours from, so it’s doable. There is a medium sized tumor behind her right eye, but her left eye is healthy. The team is amazing, the doctor is super confident, and the prognosis is good, but it’s still scary. If anyone is curious, here’s an article on the eye cancer my daughter has and the treatment she’ll be getting just like this little girl did: https://pulse.seattlechildrens.org/a-mothers-intuition-leads-to-picture-perfect-treatment-of-retinoblastoma/amp/?fbclid=IwAR2taI_srhF_wX-D2KzBv_JzJTsCdsbjgB2khq2AN5km1Jg-UzmsxU1zAgQ

Also it’s good to be aware of ways to spot it if you have kids of your own. It’s genetic and rare, but you never know. Ellie is adopted, so we didn’t know to look for anything.

We will be back and forth to Stanford for awhile. Ellie has no clue she has cancer because she feels no pain from it (her eye literally flutters and shakes which is the only way we noticed anything wrong) so on our “off” days we are still going to splash pads, discovery museums, and other things that entertain kids. We are tired, but you gotta just go, go, go. Thanks for the nice words from my post before. I know this is just simblr, but I feel I’ve made some nice connections here over the years and I didn’t want to disappear without any word.

Talk soon. <3

[here-to-shine]

its International Childhood Cancer Day today.

lets spread awareness heres some facts about childhood cancer:

1. each year, more than 300,000 children ages birth to 19 years are diagnosed with cancer around the world. And approximately 8 in 10 of these children live in low and middle-income countries where their survival rate is often near 20%.

2. Every 3 minutes, a child dies of cancer, although more than 80% of children with cancer can survive, living full and healthy lives with access to quality care.

3. The most common types of childhood cancer include leukaemia (a third of all cancers in children is leukaemia), tumours of the central nervous system, neuroblastoma, nephroblastoma, medulloblastoma, and retinoblastoma.

4. Only a few known risk factors for childhood cancer have been identified and these include - problems with development in the womb, medical conditions, exposure to infections, exposure to radiation, previous cancer treatments, etc. Doctors believe that genetics may play a role in the development of childhood cancer.

5. According to the American Cancer Society, childhood cancer makes up less than 1% of all cancers diagnosed each year.

My heart goes to all who has ever had to deal with cancer. much love to all of you. 

[manipal]

Cancer in Children: Types and Symptoms

What is Cancer in Children?

Cancer is defined as an abnormal growth of cells in the body and these abnormal cells invade into surrounding normal structures causing damage to them and can also spread to other parts of the body. Apart from cancer involving blood and lymph nodes (leukaemia and lymphoma), solid organs can also get afflicted by cancer in children. They can arise anywhere in the body but commonly involve the brain, kidney, liver and eyes. The cancers in children are different from adult cancers and the treatment protocols also vary.

Childhood Cancer Causes

In India, roughly 70,000-80,000 childhood cancer cases are diagnosed every year. The exact reason for cancer in children is unknown. However, about 5% can be because of genetic predisposition (i.e history of cancer in the family) or because of defects in the genes associated with particular cancer. Certain drugs taken by the mother during pregnancy can also predispose.

Childhood Cancer Symptoms

The symptoms vary as per the organ/system involved. However, being aware of common symptoms is important and should prompt parents to consult a doctor. As an example, kidney tumours can cause blood in the urine or liver tumours can cause jaundice and brain tumours can cause neurological symptoms.

When to consult a doctor?

Consult a cancer specialist in India if you feel:

1. Lump anywhere in the body especially the abdomen, head, neck, testes, extremities. The lump may be painless and gradually increase in size.

2.  Unexplained fever with loss of weight and appetite

3.  Pallor, easy bruising or bleeding, body aches, easy fracture of bones with trivial injury

4.  White spot in the eye or recently noticed squint, loss of vision or protruding eyes, rapid movement of eyes

5.  Unusual behaviour or movements

6.  Blood in urine or stools

Common childhood cancers are Leukemia, lymphomas, brain tumours, Neuroblastoma, Wilm’s tumour, Rhabdomyosarcoma,  Hepatoblastoma and Retinoblastoma.

How is it diagnosed?

Clinical examination by a doctor is most important and solid organ tumours can be easily diagnosed:

Blood and urine tests

Radiological investigations as ultrasound, CT scan, MRI scan

Specialised radionucleotide scans as PET scan, MIBG scan or DOTA scan may be needed in selected patients

Bone marrow aspiration and biopsy

Biopsy from cancer. A small piece from the cancer is taken by a needle or small surgery to determine the type of cancer, its virulence and spread. It helps to plan and start the treatment

What treatment options are available?

The type of cancer, tumour load and staging help in deciding the treatment plan. This helps in reducing the treatment burden for cancers that are less malignant. This is called risk stratification.

1. Surgery:  It plays a very important role in cancer diagnosis and local treatment. Surgery plays an important in local treatment of solid tumours. The plan for surgery depends on the site and organ involved. It may be the only therapy needed for small tumours.

2. Chemotherapy:  These are the drugs given to stop cancer cells from multiplying, destroying abnormal cells and preventing the cancer cells to spread in the body. Chemotherapy also helps in shrinking the tumour and thus make removing of very large tumours feasible if they are chemosensitive. The drugs are very strong and are used in various combinations. They are given for varying durations. The common side effects of chemotherapy include nausea, vomiting, loss of appetite, loss of hair, and bone marrow suppression. Certain drugs may affect the heart or kidneys.

3. Radiation: High energy beams of energy are used to kill cancer cells and are delivered through a machine. The treatment is painless but the child needs to be still when this treatment is being given. So the child may need sedation to make him sleep on the table for 10-30 min and treatment may take a few weeks.

4. Bone marrow transplant: This modality is being used these days more frequently to achieve a cure from cancer. Here the stem cell transplants replace the diseased or damaged bone marrow cells with healthy and new mature cells

5. Advanced treatments as liver transplant or kidney transplant may be necessary.

Types of Operations/Surgery

The operation depends on the site of cancer and the organ involved. The surgical procedure can be

1) Biopsy

2) Tumour removal

3)  Chemoport or Hickman catheter placement for long term venous access so that child is not pricked frequently

4) Bypassing any obstructions caused by the tumour

5) Any complications which can be managed by surgery

What is the outlook or future of these children?

The outcome of childhood cancer depends on the type, stage and spread of cancer. It also depends on the effectiveness of surgical removal and response to chemotherapy and radiation. In tumours that are in the early stage, a cure rate of 90% can be achieved whereas a 70% survival in high-grade tumours is frequently seen. Overall the outlook for childhood cancer is good and many of these cancers are curable with minimal long term side effects. Visit the best cancer hospital in India for safeguarding your child's health.

[myabhijitr]

Fibrosarcoma Drugs Market is Estimated to Augment Growth by 2028 | Bristol-Myers Squibb Company, Dr. Reddy’s Laboratories Ltd., Baxter International

Fibrosarcoma is a rare type of soft tissue malignant tumor composed solely of fiber-forming connective tissue called fibroblasts. Although this condition can occur at any age, it is commonly diagnosed between the age of 30-60 years. Individuals, who are suffering from genetic health conditions such as nevoid basal cell carcinoma syndrome, retinoblastoma, are more prone to have fibrosarcoma. However, the precise cause of the disease is unknown. Individuals going through radiation treatment or suffering from lymphedema or getting exposed to chemicals such as arsenic, or thorium dioxide vinyl chloride are more likely to suffer from fibrosarcoma. This disease is symptomized by muscular pain, which increases exponentially with time. It is diagnosed by bone lesions in the radiograph, followed by advanced imaging and laboratory test and confirmed by biopsy results. Treatment of the disease depends on the stage of the tumor during diagnosis. Surgery and radiation therapy are the treatment used for fibrosarcoma.  Currently, a limited number of treatment methods and various side effects of chemotherapy such as hair loss or low blood platelet count are propelling demand for research and development activities in fibrosarcoma treatment.

Get PDF Sample Copy (Including Full TOC, List of Tables & Figures, Chart) @ https://www.coherentmarketinsights.com/insight/request-sample/1495

Fibrosarcoma Drugs Market Driver

Increasing research activities are expected to fuel the growth of the fibrosarcoma drugs market over the forecast period. Fibrosarcoma being a malignant tumor requires early removal through complete eradication of malignant cells by chemotherapy. Currently, available chemotherapy includes side effects such as acquiring multi-drug resistance (MDR), severe side effects, and a high rate of reoccurrence, which in turn demands a safer drug for chemotherapy.

For instance, Loxo Oncology Inc., 2017, received US FDA approval for an investigational new drug application for LOXO 195, a next-generation TRK inhibitor for treating individuals suffering from cancers that have acquired resistance to primary TRK therapy such as larotrectinib. Moreover, in the same year, LOXO oncology announced a partnership with Bayer for the global development and commercialization of Larotrectinib and LOXO-195. The novel drug combination studies, a clinical trial for targeted drug delivery, and genetic profile-based medication are expected to boost the growth of the fibrosarcoma drugs market over the forecast period.

The increasing prevalence of fibrosarcoma is expected to augment the growth of the fibrosarcoma drugs market. According to the American Society of Clinical Oncology, 2017, around 3260 individuals were diagnosed with primary bone cancer in the U.S. out of which 4% of adults are suffering from fibrosarcoma, and the prevalence of the disease is higher in men than in women. Currently, the diagnosis facility lacks in early and accurate detection of fibrosarcoma. Therefore, raising awareness for disease and advancement in diagnostic as well as therapeutic procedures are expected to propel the growth of the fibrosarcoma drugs market.

Request PDF Brochure with Latest Insights @ https://www.coherentmarketinsights.com/insight/request-pdf/1495

Furthermore, companies, universities, and institutes are taking initiatives to provide inexpensive, readily available drugs with fewer side-effects as compared to present drugs that will help key players to strengthen product portfolio, in turn driving the growth of the fibrosarcoma drug market. Key players, as well as government organizations such as the Nation Cancer Institute or American Society of Clinical Oncology, sponsors or collaborate for the development of novel therapies and drugs. For instance, Bayer partners with loxo oncology to develop and commercialize cancer treatments. Bristol-Myers Squibb Company took over IFM Therapeutics, 2017, to have right on preclinical stimulator of interferon genes (STING) and NLRP3 agonist programs. This is focused on advancing the innate immune response for tumors.

Fibrosarcoma Drugs Market- Regional Analysis

The global fibrosarcoma market is projected to hold a dominant position in North America over the forecast period, due to increasing research activities leading to better fibrosarcoma treatment. Furthermore, well-developed healthcare infrastructure is fuelling the growth of the fibrosarcoma market. The Asia Pacific is expected to be the fastest-growing market over the forecast period due to developing healthcare infrastructure and rising awareness regarding conditions of fibrosarcoma.

Fibrosarcoma Drugs Market- Competitor

Major players operating in the fibrosarcoma drugs market include Celon Laboratories Pvt. Ltd., Johnson & Johnson., Pfizer Limited, Eli Lilly and Company, Baxter International Inc., Sun Pharmaceutical Industries Ltd., Dr. Reddy’s Laboratories Ltd., Bristol-Myers Squibb Company, and Cadila Healthcare Limited.

[gastrosurgerysurat]

What Gastrointestinal Cancers develop in Young Children?

Childhood is the most beautiful of all life's seasons! But not every child is lucky enough to enjoy their childhood care-free. For children fighting the battle of cancer, the young years can be difficult. It is important to remember that early diagnosis and timely medical treatment can help in saving the child and curing them of cancer.

To spread awareness regarding pediatric cancer, promote the benefits of early diagnosis, and raise funds for families dealing with childhood cancer, India observes September as Childhood Cancer Awareness Month.

Childhood Cancer: Understanding the Menacing Problem

Every year, 300,000 children are diagnosed with cancer. It is 3-4% of total annual cancer cases detected globally. If we consider the Indian statistics, doctors diagnose 40,000-50,000 childhood cancer cases every year. Although 70-90% of pediatric cancers are curable, the estimate suggests that 70% of kids in India die due to:

1. Lack of awareness

2. Late detection and diagnosis

3. Inability to access medical facilities

4. High treatment cost

5. Unavailability of supportive care.

What Types of Gastrointestinal Cancers develop in Children?

The most common pediatric cancers are leukemia, brain, and spinal cord tumors, neuroblastoma, retinoblastoma, bone cancer, Wilms tumor, lymphoma, etc. When it comes to gastrointestinal cancer, surgical gastroenterologists often witness hepatoblastoma and pancreatoblastoma in children.

1. Hepatoblastoma: Malignant Liver Cancer among the Young  

Hepatoblastoma is a type of liver cancer occurring in infants, toddlers, and children. It is a rare type of cancer that often affects children under the age of 3-4 years. GI surgeons have noticed that hepatoblastoma usually does not spread to other parts of the body.

Although the exact cause of the disease is unknown, experts pinpoint genetics. Beckwith-Wiedemann syndrome, familial adenomatous polyposis, glycogen storage diseases, and Aicardi syndrome increase the risk of hepatoblastoma in young children. If a baby is born with low weight, it can affect the risk of developing the disease.

Are there any Symptoms of Hepatoblastoma?  

The signs of hepatoblastoma vary depending on the size of the tumor. However, one must look for the following symptoms:

a. Lump/swelling in the belly area

b. Enlargement of veins in the abdominal area

c. Pain in the abdomen

d. Trouble in eating and loss of appetite

e. Fatigue and unexplained weight loss

f. Nausea and vomiting

g. Fever

h. Jaundice

i. Itchy skin

If you notice any of the symptoms of hepatoblastoma, consult a surgical gastroenterologist immediately. The doctor can diagnose the disease after a physical examination, blood tests, ultrasound, tumor biopsy, CT scan, and MRI scan. The patient may have to undergo liver resection surgery, chemotherapy, and radiation therapy to treat hepatoblastoma. After the treatment, regular follow-ups are crucial.

2. Pancreatoblastoma: Rare Pancreatic Malignancy in Children

Malignant pancreatic tumors are different in children than those seen in adults. Additionally, they have better clinical outcomes in the younger population. Surgical gastroenterologists, oncologists, and other health care providers have noticed pancreatoblastoma almost exclusively in young children (age range: up to 9 years).

Pancreatoblastoma, pancreaticoblastoma, or infantile-type carcinoma of the pancreas is the most common type of pancreatic tumor in younger children. It causes less than 0.2% of pediatric cancer-related deaths in children. It means early detection and early medical treatment can help the child fight the disease successfully.

What are the Symptoms of Pancreatoblastoma?

Although the disease can be asymptomatic, parents and primary caregivers of the child must look for the following signs:

1. Abdominal pain and swelling

2. Fatigue and lethargy

3. Anorexia and weight loss

4. Diarrhea

5. Nausea and vomiting

Predominantly, the male children among the Asian population are affected by pancreatoblastoma. Doctors believe that congenital cases of the disease have some link to Beckwith-Wiedemann syndrome.

The surgical gastroenterologist will recommend tests: sonography, CT scan, MRI scan, etc., to diagnose pancreaticoblastoma. After a successful diagnosis, the young patient may need surgical pancreatic resection to remove the tumor.

Treatment, Care, and Support is Necessary

Childhood cancer can affect the young patient physiologically as well as emotionally. With immediate medical treatment, the emotional support of a counselor or support group is essential to help the child and family members.

To fight against the terrible disease, children need to undergo regular medical screening. Additionally, we need more childhood cancer awareness, better medical infrastructure, and improved public health strategies to avoid losing our future generation.

[wetakeoncancer]

DID YOU KNOW? 🤔 Childhood cancer makeup less than 1% of all cancers diagnosed each year. It’s less likely to be caused by the patient’s environment or lifestyle. Cancer-causing genetic changes (called mutations) are most commonly thought to occur by chance. However, in about 8% of cases children are born with genetic changes that increase their risk of getting cancer. Leukemia, a blood cancer is the most common childhood cancer. Other cancers that typically attack children include: • Brain and spinal cord tumors • Neuroblastoma • Wilms tumor (Kidney) • Lymphoma (Lymph nodes) • Rhabdomyosarcoma (soft tissue/muscle) • Retinoblastoma(eye) • Bone cancer (osteosarcoma and Ewing sarcoma) Cancer ribbon is Gold 🎗 Awareness month is September. #WETakeOnCancer #WTOC #KidCancer #Childhoodcancer #Facts #Genetics #DNA #Awareness #Leukemia #Sarcoma #WilmsTumor #CHC #Childhoodcancerawarenessmonth https://www.instagram.com/p/CTfC4ptgBqY/?utm_medium=tumblr

[chitrakullkarni]

Cryotherapy Market Size, Emerging Trends, Growth Opportunities and Current Scenario, 2024

The global Cryotherapy Market research report provides complete insights on industry scope, trends, regional estimates, key application, competitive landscape and financial performance of prominent players. It also offers ready data-driven answers to several industry-level questions. This study enables numerous opportunities for the market players to invest in research and development.

Market Overview:

Global Cryotherapy Market is anticipated to reach USD 5.6 billion by 2024 owing to the increasing demand for minimally invasive surgical procedures and the growing incidences of cervical, retinoblastoma, prostrate, skin cancer and others. Cryotherapy is basically the procedure of using cold temperatures for health benefits. This type of therapy has been into use since long to reduce pain and muscle spasms, show cell ageing and improve health recovery.

Key Players:

CryoConcepts LP

Medtronic

Mectronic Medicale s.r.l.

Wallach Surgical Devices

Brymill Cryogenic Systems

CooperSurgical, Inc.

Cortex Technology

Metrum Cryoflex

Cryoalfa

Erbe Elektromedizin GmbH

Galil Medical, Inc.

Physiomed Elektromedizin AG

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Growth Drivers:

The therapy reduces irritation, muscle swelling and pain. It cures several diseases and helps in surgical procedures as well. Over the years, cryotherapy has gained huge popularity and has become an accessible form of therapy. Since cryotherapy is a minimally invasive therapy, it is more preferred for open surgeries. Owing to this, the demand of cryotherapy is growing, thereby boosting cryotherapy industry. Also, as the application is localized and constrained to the abnormal tissues, healthy tissues are well maintained, which reduce the side effects.

Even though there are numerous advantages of cryosurgery, most disadvantages have constrained the market growth. Few side effects of cryosurgery can be stated as hypopigmentation, erythema and pain. Less effectiveness of cryotherapy is majorly hampering the growth of cryotherapy market. Also, insufficient clinical information, and low awareness has resulted in low reimbursement. Conversely, as the technology is advancing, the downsides are expected to fade away, which will drive the market of cryotherapy in the years to come.

In various incidences of cancers, cryosurgery offers benefits like less complications, low pain and short period of hospital stay that is ideal for conventional surgeries. This will ultimately increase the demand for cryotherapy, thereby boosting cryotherapy industry. Cryotherapy is also regarded advantageous for patients that are non-responsive to treatments and cannot be treated. Owing to the increase in cancer patients worldwide, the market is also predicted to grow in the near future. Additionally, the rising investment in healthcare segment by the emerging nations will also stimulate the growth of the market of cryotherapy.

Furthermore, high success rate of cryotherapy and its cost-effectiveness is predicted to drive cryotherapy market growth in future. Moreover, extensive adoption by the athletes and sports associations and advantageous reimbursement policies are also impacting the growth of the market at a prominent rate.

Therapy Type Outlook:

Cryosurgery

Icepack Therapy

Chamber Therapy

Application Outlook:

Oncology

Cardiology

Dermatology

Pain management

Others (ophthalmology and gynecology )

Regional Outlook:

Geographically, cryotherapy market is segmented as North America, Europe, Asia Pacific, and Rest of the World (RoW). North America segment is expected to hold larger market share of cryotherapy owing to growing popularity of cryosaunas and rising prevalence of cancers.

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Cryotherapy Market Statistics, Growth Prediction, Competitive Research And Outlook till 2024

July 30, 2021: Global Cryotherapy Market is anticipated to reach USD 5.6 billion by 2024 owing to the increasing demand for minimally invasive surgical procedures and the growing incidences of cervical, retinoblastoma, prostrate, skin cancer and others. Cryotherapy is basically the procedure of using cold temperatures for health benefits. This type of therapy has been into use since long to reduce pain and muscle spasms, show cell ageing and improve health recovery. The therapy reduces irritation, muscle swelling and pain. It cures several diseases and helps in surgical procedures as well. Over the years, cryotherapy has gained huge popularity and has become an accessible form of therapy.

Since cryotherapy is a minimally invasive therapy, it is more preferred for open surgeries. Owing to this, the demand of cryotherapy is growing, thereby boosting cryotherapy industry. Also, as the application is localized and constrained to the abnormal tissues, healthy tissues are well maintained, which reduce the side effects. Cryotherapy surgery is also used in combination with other treatments like radiation, chemotherapy, hormone therapy and reduce the use of drugs for producing side effects.

Even though there are numerous advantages of cryosurgery, most disadvantages have constrained the market growth. Few side effects of cryosurgery can be stated as hypopigmentation, erythema and pain. Less effectiveness of cryotherapy is majorly hampering the growth of cryotherapy market. Also, insufficient clinical information, and low awareness has resulted in low reimbursement. Conversely, as the technology is advancing, the downsides are expected to fade away, which will drive the market of cryotherapy in the years to come.

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In various incidences of cancers, cryosurgery offers benefits like less complications, low pain and short period of hospital stay that is ideal for conventional surgeries. This will ultimately increase the demand for cryotherapy, thereby boosting cryotherapy industry. Cryotherapy is also regarded advantageous for patients that are non-responsive to treatments and cannot be treated. Owing to the increase in cancer patients worldwide, the market is also predicted to grow in the near future. Additionally, the rising investment in healthcare segment by the emerging nations will also stimulate the growth of the market of cryotherapy.

Furthermore, high success rate of cryotherapy and its cost-effectiveness is predicted to drive cryotherapy market growth in future. Moreover, extensive adoption by the athletes and sports associations and advantageous reimbursement policies are also impacting the growth of the market at a prominent rate.

Cryotherapy industry is categorized on the basis of product, application, end user, and geography. On the basis of product, the market is divided into cryosurgery devices, tissue contact probes, tissue spray probes, epidermal & subcutaneous cryoablation devices, localized cryotherapy devices, and cryo chambers & cryosaunas. Cryosurgery devices segment is expected to register high growth in the forecast period due to rising patient’s preference for minimally invasive procedures and innovations in cryosurgery devices.

Based on application, the market of cryotherapy is split into surgical applications, oncology, cardiology, dermatology, other surgical applications, pain management, and recovery, health & beauty. Surgical application segment is predicted to grow significantly in the coming years. On the basis of end user, the industry is classified into hospitals & specialty clinics, cryotherapy centers, and spas & fitness centers.

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Geographically, cryotherapy market is segmented as North America, Europe, Asia Pacific, and Rest of the World (RoW). North America segment is expected to hold larger market share of cryotherapy owing to growing popularity of cryosaunas and rising prevalence of cancers. The key players in cryotherapy industry are ErbeElektromedizin GmbH, KrioSystem Sp. z.o.o., Zimmer MedizinSysteme GmbH, Impact Cryotherapy Inc., MetrumCryoflex Sp. z o.o., Sp. K., Novotech S.R.O, Air Products and Chemicals, Inc. etc., and The Cooper Companies Inc. among others.

Market Segment:

Cryotherapy Market Therapy Type Outlook (Revenue, USD Million, 2013 - 2024)

• Cryosurgery

• Icepack Therapy

• Chamber Therapy

Cryotherapy Device Type Outlook (Revenue, USD Million, 2013 - 2024)

• Cryoguns

• Cryo probes

• Gas cylinders

• Others ( Cryo chambers, gas pressure gauges, and thermocouple devices)

Cryotherapy Application Type Outlook (Revenue, USD Million, 2013 - 2024)

• Oncology

• Cardiology

• Dermatology

• Pain management

• Others (ophthalmology and gynecology)

Cryotherapy Market Regional Outlook (Revenue, USD Million, 2013 - 2024)

• North America

• U.S.

• Canada

• Europe

• UK

• Germany

• Asia Pacific

• Japan

• China

• India

• Latin America

• Brazil

• Mexico

• Middle East and Africa

• South Africa

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Retinal Biologics Market Size, Key Players Analysis And Forecast To 2027 | Value Market Research

The Retinal Biologics Market research report provides the latest industry data, growth, key segments and future trends on the basis of the detailed study. This market report also allows you to identify the future opportunity and growth rate of the leading segment based on regions and countries.

The research report also covers the comprehensive profiles of the key players in the market and an in-depth view of the competitive landscape worldwide. The major players in the retinal biologics market include F. Hoffmann-La Roche Ltd,Regeneron Pharmaceuticals Inc.,AbbVie Inc.,MeiraGTx Limited,Oxurion NV,Others. This section includes a holistic view of the competitive landscape that includes various strategic developments such as key mergers & acquisitions, future capacities, partnerships, financial overviews, collaborations, new product developments, new product launches, and other developments.

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Market Dynamics

The retinal biologics market is witnessing significant momentum in recent years due to the escalation of ophthalmic disorders worldwide. Growing instances of retinal conditions like macular degeneration related to age, infectious retinitis, macular edema, diabetic retinopathy, macular hole, retinoblastoma, retinal degeneration, uveitis, and retinoschisis leading to a permanent loss of vision will be the primary stimulant for the growth of this market. Consistent efforts in developing innovative treatment options, increased investments in the ophthalmology sector to raise awareness and diagnosis of different disorders related to the eye will be a market booster. The high treatment cost and limited long-term safety will hamper market growth since retinal biologics is not considered first-line therapy in most patients. The report covers Porter’s Five Forces Model, Market Attractiveness Analysis and Value Chain analysis. These tools help to get a clear picture of the industry’s structure and evaluate the competition attractiveness at a global level. Additionally, these tools also give inclusive assessment of each segment in the global market of retinal biologics.

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Market Segmentation

This section of the retinal biologics market report provides detailed data on the segments by analyzing them geographically, thereby assisting the strategist in identifying the target demographics for the respective product or service.

By Drug Class

VEGF-A Antagonist

TNF-a Inhibitor

By Disease Indication

Macular Degeneration

Diabetic Retinopathy

Uveitis

Others

Regional Analysis

This section covers regional segmentation which accentuates on current and future demand for Retinal Biologics market across North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. Further, the report focuses on demand for individual application segment across all the prominent regions.

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