#Karolina Sikorska

[modelpluswarsaw]

Karolina Sikorska for ROSEKEY Jewellery Campaign captured by  Frederico Martins

[polishmodels]

Karolina Sikorska - editorial "Shape Up" for VOGUE China, March 2023

Photographed by David Paige

source: forums.thefashionspot.com

[emilia-jasinska-producer]

REŻYSERIA: Karolina Porcari SCENARIUSZ: Karolina Porcari, Krzysztof Szekalski OPERATOR: Tomasz Wierzbicki MONTAŻ: Anna Morawiec OBSADA: Katarzyna Figura, Piotr Cyrwus, Małgorzata Bogdańska MUZYKA: Joanna Halszka Sokołowska, Daniel Pigoński, Hubert Zelmer DŹWIĘK: Bartosz Putkiewicz, Natalia Sikorska PRODUCENT: Studio Munka KOPRODUCENT: Mizar Films, TVN, All For Movies, Boss of Toys

[zija-pioro]

[cancersfakianakis1]

The prognostic and potentially predictive value of the Laurén classification in oesophageal adenocarcinoma

Publication date: May 2017 Source:European Journal of Cancer, Volume 76 Author(s): Rosa T. van der Kaaij, Petur Snaebjornsson, Francine E.M. Voncken, Jolanda M. van Dieren, Edwin P.M. Jansen, Karolina Sikorska, Annemieke Cats, Johanna W. van Sandick AimTo investigate the histological subtypes of oesophageal adenocarcinoma according to the Laurén classification (intestinal/diffuse/mixed) in relation to tumour response to neoadjuvant treatment, and in relation to patients' survival after potentially curative treatment.MethodsData were collected from all oesophageal adenocarcinoma patients who underwent potentially curative treatment in our institute between 1998 and 2014. Treatment consisted of neoadjuvant chemoradiotherapy (36–50 Gy) followed by an oesophagectomy or definitive chemoradiotherapy (50–50.4 Gy). Clinical data were collected from patient records. All endoscopic biopsies and surgical resection specimens were reassessed to determine the histological subtype (intestinal, diffuse or mixed) and the Mandard tumour regression grade (TRG). The impact of the histological subtypes on survival was determined using a Cox model.ResultsMedian follow-up was 68 months. Diffuse and mixed type cancers accounted for 25% of oesophageal adenocarcinomas. Median overall survival differed significantly between patients with intestinal (n = 121, 39 months), diffuse (n = 28, 18 months) or mixed type (n = 11, 25 months) carcinomas (log rank, p = 0.023). In multivariable analysis, the diffuse type was associated with shorter survival (diffuse versus intestinal: hazard ratios 2.06, p = 0.006). A pathologically (near) complete response (TRG 1 or 2) was seen less frequently in diffuse type than in intestinal type carcinomas (24% versus 60%; p = 0.015).ConclusionsPatients with diffuse type oesophageal adenocarcinomas had a significantly worse prognosis than those with intestinal type carcinomas. Intestinal type carcinomas showed a better response to neoadjuvant chemoradiotherapy than diffuse type carcinomas. These differences call for the exploration of differentiated approaches in the potentially curative treatment of oesophageal adenocarcinomas. http://ift.tt/2lps5Ex

[lyssahumana]

[pyrrh-ic]

Out of Imagination Vogue Thailand May 2014

Karolina Sikorska ph. by Nat Prakobsantisuk (3/3)

[okyeahsurewhatever]

"Out of Imagination" Karolina Sikorska by Nat Prakobsantisuk Vogue Thailand May 2014

[modelpluswarsaw]

Karolina Sikorska Cover Story  for  Damernas Värld captured by  Ahmet Unver

[polishmodels]

Karolina Sikorska - editorial "Shape Up" for VOGUE China, March 2023

Photographed by David Paige

source: forums.thefashionspot.com

[orangadore]

[zija-pioro]

[beautifullytwistedmind]

[beautifullytwistedmindfashion]

Vogue Thailand | "Out of Imagination" | Nat Prakobsantisuk | Jirat Subpisankul | Karolina Sikorska | May 2014

[pyrrh-ic]

Out of Imagination Vogue Thailand May 2014

Karolina Sikorska ph. by Nat Prakobsantisuk (2/3)

[andplentymore]

'Out Of Imagination' with Karolina Sikorska by Nat Prakobsantisuk for Vogue Thailand May 2014, styled by Jirat Subpisankul.