#Jingwei wan
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mqfx · 1 month ago
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the knife shows up 3 times lol. MASSIVE SPOILERS FOR WOMEN ENJOYERS
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winttube · 2 years ago
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Jingwei wan
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Institute of Biomedical and Clinical Science.Web of Science ResearcherID: Q-7959-2019.This current discovery could address the urgent need for treatment that could provide an effective alternative to invasive surgery. Brain swelling after a stroke or epilepsy is a common and devastating problem for individuals and their families. NCC, NKCC2, NKCC1, KCC2 and KCC3, and their upstream regulatory mechanism by the WNK-SPAK/OSR1 signalling pathway in mammalian cells and tissues under physiological and pathological conditions (Cell Metabolism 2017 Nature Medicine 2017 Nature Communications 2017  eLife 2018 Neuron 2019 Science Signalling 2019a, 2019b Molecular Psychiatry 2021 and Genetics in Medicine 2022), and subsequently led to the development of a drug-like molecular ZT-1a (Nature Communications 2020 Stroke 2022 US Patent WO2020072386, European Patent EP3873439 (A1), Canadian Patent CA3115075 (A1), China Patent CN113365614 (A)), as a neuroprotective agent. Recent research in Zhang Laboratory has greatly improved our understanding of the function of Chloride ion transporters, e.g. In 2017, Jinwei joined the Faculty of the University of Exeter Medical School, where his KCC2/ NKCC1 investigations can gain greater impact by integration with the clinical resources and basic science research at The Institute of Biomedical and Clinical Sciences. Since 2014, Jinwei's research focused on CU元/KLH元-WNKs-SPAK/OSR1-cation chloride cotransporters (CCCs) signalling in cellular chloride homeostasis and cell volume regulation in collaboration with Professor Kristopher Kahle at Yale University School of Medicine. While there, he studied LRRK2 associated Parkinson's disease, and contributed to the discovery of the most potent LRRK2 kinase inhibitors TAE684 and TTT3002, most selective LRRK2 inhibitor GSK2578215A, and the first brain penetrable LRRK2 inhibitors HG-10-102-01 and JH-II-127. Since 2011, Jinwei pursued his interest in cellular signalling with a post-doctoral fellowship at the Medical Research Council (MRC)- Protein Phosphorylation and Ubiquitination Unit (PPU) in Dundee with Professor Dario Alessi (FRS), and with Professor Nathanael Gray at Harvard Medical School. While there, he studied natural bioactive compounds and their applications in human health. He then obtained a PhD degree in Biotechnology from Newcastle University UK in 2011. While there, he studied marine ecology and cold-adapted enzymes from deep-sea bacteria. He then obtained a MSc degree in Marine Microbial Biochemistry and Molecular Biology at The Third Institute of Oceanography (Xiamen), State Oceanic Administration China in 2007. While there, he studied mutagenesis of Aspergillus niger for higher yield of multicomponent enzymes. Fellow of the Higher Education Academy, 2019ĭr Jinwei Zhang obtained a BSc degree in Bioengineering from Fujian Normal University China in 2003.PhD, 2011, Newcastle University, Newcastle upon Tyne, UK.MSc, 2007, Xiamen University (Xiamen City), and the Third Institute of Oceanography (Xiamen City), State Oceanic Administration, China.BSc, 2003, Fujian Normal University (Fuzhou City), China.All these studies concern with elucidating and targeting ion transporters, kinases, protein-protein interactions using genetic mouse models, mass spectrometry, small molecules, electrophysiology, and CRISPR/Cas9 gene editing technologies to aid discovery and validation of new potential drug targets. He studies signalling pathways that associated with human diseases, for examples, the neurodegenerative diseases including the LRRK2 associated Parkinson's disease (PD), the amyloid precursor protein (APP) and Tau associated Alzheimer's disease (AD), neuropsychiatric disorders including epilepsy (WNK-SPAK-KCC2), High Blood Pressure & Kidney Disease (CU元/KLH元-WNK-SPAK-NCC) etc. He gained a solid theory and practice of training in the field of natural bioactive compounds, biochemistry and molecular biology, enzymology, pharmacology, drug discovery, signaling transduction and electrophysiology during his academic degrees and postdoc trainings. Dr Jinwei Zhang has a very wide-ranging expertise, which makes him uniquely positioned to develop research at the interface between fields.
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chinesetong-china · 4 years ago
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Learn Chinese and Chinese Culture in stories|Chinese legends|The bird Ji...
Learn Chinese and Chinese Culture in stories|Chinese legends|The bird Jingwei fill up the sea with pebbles‘jing wei tian hai’
 In the East China Sea, A bird named Jingwei brought pebbles into the sea day after day, and tried to fill the sea. The sea laughed:" Little bird, you can not fill me up even you do this for a thousand years ." The bird replied ," Even for a million years, I will fill you up ." This is the well-known story of ‘Jingwei tian hai’ in China.
 The idiom "Jingwei Tian Hai" represents the struggle of human beings against the fate and nature, which symbolizes the spirit of never giving in to suffering.
 在东海上,有只名叫精卫的小鸟日复一日地衔来树枝石头填入海中,它要把大海填平。大海嘲笑道:‘小鸟儿,你这样就算干上一千年,也休想把我填平’。小鸟回答道‘就算是一百万年,我也要把你填平’。这就是中国家喻户晓的‘精卫填海’的故事。
 ‘精卫填海’这个成语表达了人类对自然命运的抗争,象征着面对磨难,永不屈服的精神.
   CONTENT
Jīng Wèi tián hǎi
精卫填海
The bird Jingwei fill up the sea with pebbles
 Yuan gu shi qi ,ren lei sheng cun jian nan
远古时期,人类生存艰难
In ancient times ,human survival was difficult
 Yan di zui xiao de nv er ming jiao Nv Wa
炎帝最小的女儿名叫女娃
Yan Emperor's youngest daughter named Nuwa
 Ta tian zhen huo po ,dui shi jie chong man hao qi
她天真活泼,对世界充满好奇
She was innocent and lively, curious about the world
 Fu wang ,tai yang shi cong shen me di fang sheng qi de
父王,太阳是从什么地方升起的
Dad, where doese the Sun rise from
 Zai dong hai ji wan li wai de gui xu
在东海几万里外的归墟
From Gui xu, which is tens of thousands miles from the East China Sea
 Shi tai yang sheng qi de di fang
是太阳升起的地方
It is where the Sun rise from
 Na li you jin yu xiu jian de gong dian
那里有金玉修建的宫殿
There are palaces built with gold and jade
 Tong ti xue bai de niao shou
通体雪白的鸟兽
All white birds and beasts
 Jie man zhen zhu de yu shu
结满珍珠的玉树
Jade trees with pearls
 Zhe me mei de di fang
这么美的地方
Such beautiful place
 Wo yi ding yao qu kan kan
我一定要去看看
I must go there and have a look
 Yi tian Nv Wa du zi hua zhe xiao chuan
一天女娃独自划着小船
One day Nv Wa rowed her boat alone
 Chao dong hai tai yang sheng qi de di fang chu fa le
朝东海太阳升起的地方出发了
to the East China Sea where the Sun rise
 Tu ran ,hai shang qi le feng bao
突然,海上起了风暴
Suddenly, there was a storm at the sea
 Yi ge ju lang ba Nv Wa de xiao chuan xian fan le
一个巨浪把女娃小船掀翻了
A huge wave overturned Nvwa's boat
 Nv Wa, ni kuai hui lai
女娃,你快回来
Nvwa, come back
 Yan di zai ku han ta de nv er
炎帝在哭喊他的女儿
Emperor Yan was crying out for his daughter
 Nv wa zai ye hui bu qu le
女娃再也回不去了
Nvwa can’t come back for ever
 Fu wang ,fu wang ,dui bu qi ,wo yao zou le
父王,父王,对不起,我要走了
Dad, Dad ,sorry , I must go
 Ni qu na er ya ,Nv Wa
你去哪儿呀,女娃
Where are you going , Nvwa
 Wu qing de da hai duo qu le wo de sheng ming
无情的大海夺取了我的生命
The merciless sea took my life
 Wo yao qu tian ping ta
我要去填平它
I am going to fill it out
 Rang da hai zai ye bu neng shang hai wo men
让大海再也不能伤害我们
Let the sea never hurt us again
 Nv Wa hua shen yi zhong shen niao
女娃化身为一种神鸟
Nuwa incarnated as a divine bird
 Ta mei tian cong xi shan xian lai shi tou he cao mu tou ru dong hai
它每天从西山衔来石头和草木投入东海
It brought stones and vegetation from the West Mountain to the East China Sea every day
 Fa chu ‘ jing wei ,jing wei ‘ de bei ming
发出‘精卫,精卫’的悲鸣
Crying ' Jingwei, Jingwei'
 Hao xiang zai hu huan ta zi ji
好像在呼唤它自己
As if calling itself
 Ri fu yi ri ,nian fu yi nian ,zhi dao jin tian
日复一日,年复一年,直到今天
Day after day, year after year, until now
  KEYPOINTS
Hǎi
��� sea; big lake; a great number of people or things gathering together; a surname
 Tián
填 fill , fill in
 Tián hǎi
填海 fill up the sea , reclaim from the sea.
 Jīng wèi tián hǎi
精卫填海
The bird Jingwei fill up the sea with pebbles
 Tā dài biǎo zhe rén lèi duì zì rán mìng yùn de kàng zhēng ,xiàng zhēng zhe miàn duì mó nàn ,yǒng bù qū fú de jīng shén
它代表着人类对自然命运的抗争,象征着面对磨难,永不屈服的精神
It represents the struggle of human beings against the fate and nature, and symbolizes the spirit of never giving in to suffering
 Yú gōng yí shān
愚公移山
The Foolish Old Man try to remove the mountains
 .....
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mqfx · 2 months ago
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ancient chinese butches. hell yeah!!!
and I gave you guys a range!!!! ke longya is soft and friendly and warm!! zhuang huilin is old and steady and no-nonsense!!! ma qiangwei is a fridged mom!! li shun is a deadbeat older sister!!!
MORE WUXIA/XIANXIA BUTCHES THAT'S AN ORDER FROM YOUR LIEGE LORD
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mqfx · 2 months ago
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behold, the mascot of wan jingwei's secret police
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mqfx · 2 months ago
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what is it with women named jing and lesbianism. I haven't met a single straight one
not sure so i tried looking up the etymology but um. i would like to state for the record that i did not name wan jingwei after wang jingwei, the president of the japanese-backed puppet government. that was an unfortunate but interesting coincidence for those who know what my jingjing's been up to before the start of this fic
wan jingwei is named after the flame emperor's daughter nüwa who fell into the sea and transformed into the legendary bird. this IS thematically relevant
also i believe it's the reason for this little jing lesbian situation
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mqfx · 2 months ago
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is everyone so fucking ready for this btw
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mqfx · 2 months ago
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accidentally made wan jingwei a little too iconic for her own goddamn good. what the fuck do you mean "gods intervening with her plans but her plans continue un-derailed" isn't even the most impactful thing that happens in her life.
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mqfx · 4 months ago
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they need to take time to giggle... guffaw...grin....gravitate....
they WERE having giggle times before this fuckass mission started ngl but do you see what being employed does to these mfs?
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mqfx · 1 month ago
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part of wjw's story is being taken seriously in a position of power as a woman, right? the rebellious choice here might be as femme as possible but i voted for four. she's making concessions because its practical but id bet her gender presentation like other things is at least a little about mind games. smiles encouragingly at her
no matter what she does she's in some type of drag. present feminine? it's unsettling and cold. present masculine? she's flouting propriety. dress neutrally? she's an abomination who blurs the bounds of the natural order. everything's a performance and nothing's underneath baby!!!!
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mqfx · 1 month ago
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"something is wrong with her god bless" god does NOT bless (vaguely gestures towards xu yinuo)
wan jingwei, a known atheist: the gods have blessed me with the heavenly mandate 🤴
xu yinuo, her exasperated god and aunt: i didn't bless anything. who raised you. 🤨
wjw: not you clearly 😒 🙄
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mqfx · 1 month ago
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what does wan jingwei like best physically about li shun im imagining the scenario you've described but like. its a diagram wjw has titled a glorious victory but li shuns arms are way beefier than they actually are & the expression vitally is one of subserviant defeat (not true to life)
(covering myself in layers and layers and layers
they were i think 15 and 16 at this point?
back in the mainland she once attended a cultivation conference (it's complicated but basically the chao was flexing by gathering the southern sects in one place and showboating) and wan jingwei was a political hostage slash ward of the emperor. and she got a front row seat to watch how li shun got her reputation as a violent and dangerous monster (which, to be fair, she was being a violent and dangerous monster. but also to defend women's wrongs, she totally had a right to do that. overreaction? yeah. but girls will be girls). li shun was NOT playing by the gentleman's rules of the sport and she had to be disqualified because she got very close to killing other competitors, to the great shame of the li and the delight of the chao
anyway. wan jingwei, no courtesy name yet so only called wan ji, escorted her out since she was only basically a random lackey at the time (plotting in her heart but she was powerless and at the lowest point in her life so far....) immediately she zoned in on this neediness and insecurity in li shun and thought she could use it to her advantage, or at least practice her (at the time, very weak) manipulation tactics on her. she was very nice, nonjudgmental, and she tried not to show fear while bandaging her up
(li shun saw right through it but found it endearing and strange)
(that was an act. wj was not actually afraid. bc she's cocky the way some ppl think they can totally tame a wild tiger. ahahah layers)
there also happened to be some problems on wj's end (some cultivator bothering her) and, tldr, she made this known to li shun who handled the problem. both testing each other. only they know what the results are. after that, they don't see each other again for a few more years. coincidentally, there appears to be a curse on the wan family--how could so many members die in succession? so odd
sorry what was the question? oh yes. wan jingwei likes li shun's hands
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mqfx · 1 month ago
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wan jingwei may not top all the time but she thinks of herself as a top. when thats not the physical reality its just a deviation from her true path a diverting aside that will not even make the footnotes in her illusory autobiography <- just yapping idk her yet
CACKLIGNGNSASLKFJFHALSFKDFJ NO BC U GOT IT. THAT'S THE ONE YOUR HONORS. ABSOLUTELY CRYINGGGGGGGGGG
WJW: i'm a top because you'll do whatever i tell you to do
LS, folding her like a . thing that folds: cishi i think we need to go over the terminology again
WJW: history will vindicate me
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mqfx · 1 month ago
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crying lightning by arctic monkeys is wan jingwei's song
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this section most especially..... yup yup
ykw it's interesting that u brought up arctic monkeys bc my sister and I were listening to Halsey yesterday and I was like "damn if it was 2014 and my OCs had playlists, jingjing would have Castle by Halsey in there and li shun would have Gasoline". I'm not gonna go through every Halsey song for every girl I made though ahahah
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mqfx · 2 months ago
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rip wan jingwei you would've loved twitter (get it. because she uses birds. tweet. like birds. also she'd love arguing with people there)
this actually made me cackle do NOT let that woman know what social media IS she WILL run a psyop on that thang and the world shall not recover from her pot-stirring!!!! like she WILL start discourse and blow up entire friend groups! it will be studied in academia for decades to come!! there will be 5 part multi-hour essays by haytch bomberman all culminating into an exposé of her masterminding the whole thing!!!!!
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mqfx · 2 months ago
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I now realize we have kind of similar OCs? named "jing" ✔ bird themed ✔ lesbian ✔ does not gaf about the heavens ✔ jing mei is like wan jingwei's femme heavenly official version I think they'd get along honestly
KSDHJKJSDFHJKHSFDJKDS i'll tell you this much, wan jingwei's not allowed to go to heaven she CANNOT be trusted with power
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