#HealthcareUpdate

[newsbites]

News from Newfoundland & Labrador, Canada, 27 August

Bob Barker, an icon of the entertainment industry, has passed away.

2. Historic Sites of NL is cutting the ribbon on a new art gallery.

3. The TCH has reopened near Clarenville Area Moose crash.

4. A Cain's Quest participant has passed away following an incident outside Québec Bar.

5. The walk in clinic at Mundy Pond is temporarily closed.

[orthotv]

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🔅 Theme: Learning the Surgical Techniques and Innovative Technologies of Arthroplasty

🔆 Conference Dates: 23-25 February, 2024 🔆 Venue: SIR HN RELIANCE FOUNDATION HOSPITAL, MUMBAI

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[sandeep-health-care]

Clinical Perspectives and Management of Edema in Chronic Venous Disease—What about Ruscus?

Background: Edema is highly prevalent in patients with cardiovascular disease and is associated with various underlying pathologic conditions, making it challenging for physicians to diagnose and manage. Methods: We report on presentations from a virtual symposium at the Annual Meeting of the European Venous Forum (25 June 2021), which examined edema classification within clinical practice, provided guidance on making differential diagnoses and reviewed evidence for the use of the treatment combination of Ruscus extract, hesperidin methyl chalcone and vitamin C. Results: The understanding of the pathophysiologic mechanisms underlying fluid build-up in chronic venous disease (CVD) is limited. Despite amendments to the classic Starling Principle, discrepancies exist between the theories proposed and real-world evidence. Given the varied disease presentations seen in edema patients, thorough clinical examinations are recommended in order to make a differential diagnosis. The recent CEAP classification update states that edema should be considered a sign of CVD. The combination of Ruscus extract, hesperidin methyl chalcone and vitamin C improves venous tone and lymph contractility and reduces macromolecule permeability and inflammation. Conclusions: Data from randomized controlled trials support guideline recommendations for the use of Ruscus extract, hesperidin methyl chalcone and vitamin C to relieve major CVD-related symptoms and edema.

Introduction

Venous disorders of the lower extremities are associated with a range of pathologic conditions, many of which present with edema, complicating the process of making a differential diagnosis [1]. Further, though treatment guidelines for chronic venous disease (CVD) are regularly updated, a range of signs and symptoms are associated with edema within the literature, such as “heaviness” and a “feeling of swelling”. This lack of consistency can result in the liberal interpretation of widely used terms and hinders the exchange of helpful clinical information [2].

A number of treatments for edema in CVD are available. One such treatment is Cyclo3®Forte (Pierre Fabre, Paris, France), which was first developed in 1959 and is a combination of an extract from the plant Ruscusaculeatus, a traditional herbal product used to relieve symptoms of discomfort and the heaviness of legs related to minor venous circulatory disturbance, and, for the symptomatic relief of itching and burning associated with hemorrhoids [3], the flavonoid hesperidin methyl chalcone and vitamin C (Ruscus/HMC/Vit C) [4]. Cyclo3®Forte is currently used across 29 countries and is recommended as a first-line treatment for the relief of the major symptoms related to CVD, as well as edema [4,5].

The current article describes presentations at a virtual symposium at the Annual Meeting of the European Venous Forum (EVF) on 25 June 2021. These presentations examined the classification of edema within clinical practice and provided guidance for making a differential diagnosis. In addition, clinical trial data are presented on the efficacy of Ruscus/HMC/Vit C for patients with CVD with edema, along with guideline recommendations on the use of Ruscus/HMC/Vit C extract.

Pathophysiology of Edema

Edema occurs as a result of capillary filtration exceeding lymphatic drainage, which results in an accumulation of fluid in the interstitial spaces. Edema is a condition often associated with venous insufficiency in the lower extremities. Two predominant forms of edema are pitting and non-pitting. In pitting edema, the application of pressure on the skin leaves an indentation, which is caused by a low concentration of protein in the fluid within the interstitial spaces [6].

The Original Starling Principle

In 1896, the Starling Principle was presented to explain microvascular fluid exchange and has been used to provide a better understanding of the pathophysiologic mechanism of fluid build-up in edema. Fundamentally, the Starling Principle proposed that fluid movement across the capillary membrane is dependent on the balance between the two opposing forces on either side of the membrane, the hydrostatic pressure gradient and the colloid osmotic pressure (COP) gradient (Figure 1) [7]. The theory supports the concept that fluid extravasation occurs on arterial segmental capillaries, and a large amount of interstitial fluid is reabsorbed across the venous segment of capillaries; meanwhile, any excess fluid is reabsorbed by the lymphatic system. As the oncotic gradient for reabsorption is between the plasma and the interstitial compartment, raising the plasma oncotic pressure should in turn increase fluid reabsorption from the extravascular compartment [7]. The Starling equation allowed for the calculation of the different pressures that affect fluid movement:

Jv=κ[(Pc−Pi)−σ(πp−πi)]

where Jv is the fluid filtration rate, κ is the hydraulic conductance of microvascular walls, Pc is the capillary hydrostatic pressure, Pi is the interstitial hydrostatic pressure, σ is the reflection coefficient, πc is the COP and πi is the interstitial oncotic pressure [7,8].

For More Info : https://www.europeanhhm.com/articles/clinical-perspectives-and-management-of-edema-in-chronic-venous-diseasewhat-about-ruscus

[astocare]

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[qwayhealthcare]

US Healthcare News Bulletin April 29 to May 05, 2022

Did you know that Connecticut legislature passed a bill this week that seeks to expand Medicaid to undocumented children who are 12 years and under?

Read more about this interesting piece of news and more updates from this week in our healthcare news story!

[vardhanayurvedahospital]

Fibroids: What are Fibroids?Fibroids Symptoms|Non Surgical Fibroid Treatment

[mschronicchronicles]

View this post on Instagram

A post shared by 📌#️⃣RachelRawTruth🍃 (@rachelrawtruth)

https://youtu.be/frglD9wF6J0 #healthcareupdates #healthcareupdates #usa #thisisallanightmare #thedailyshow #hadtoshare #weresoscrewed #wellness #goodbye #money #living #thetwilightzone #painintheass #healthychoices #today #ourcountry #lol #share #watch #youtube

[orthotv]

🔰IAACON 2023 - 19th Annual Conference of Indian Arthroplasty Association

🔆THEME : Right Technology for the Right Outcome

🗓️ Date : 13th -15th October 2023 🏟️ Venue : JW Marriott, Chandigarh

🔆Click here to Register : https://bit.ly/OrthoTV-IAACON-2023

👨‍⚕️ ORGANISING SECRETARY: Dr. Manuj Wadhwa

🤝 Media partner : OrthoTV Global

[qwayhealthcare]

US Healthcare News Bulletin April 15 to 21, 2022

An interesting piece of news came up from Cedars-Sinai this week where a physician is leading a research lab and using virtual reality for treating chronic pain conditions.

The facility creates virtual reality conditions for their patients, after which they start monitoring their biometric data for deep insights.

Check out this story and other events that made it to the news last week in our consolidated blog.

[qwayhealthcare]

US Healthcare News Bulletin April 15 to 21, 2022

QWay Healthcare brings you the weekly news updates from the American healthcare industry.

Glance through to see what you might have missed.

[astocare]

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[astocare]

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[astocare]

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[astocare]

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