#Goodpasture syndrome (GPS

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“Goodpasture Syndrome”, Victor McKusick, Mendelian Inheritance in Man, 1966. 良好牧场综合症。

Here I present: “Goodpasture Syndrome”, Victor McKusick, Mendelian Inheritance in Man’, 1966. 良好牧场综合症。 INTRODUCTION. Goodpasture syndrome (GPS), is an autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs, glomerulonephritis, and kidney failure. It is thought to attack the alpha–3 subunit of type-IV collagen. Type IV collagen…

[ainudsnr]

Goodpasture syndrome (GPS) also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture’s antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

 Signs and Symptoms The anti-glomerular basement membrane (GBM) antibodies primarily attack the kidneys and lungs, although, generalised symptoms like malaise, weight loss, fatigue, fever, and chills are also common, as are joint aches and pains

Lung symptoms usually antedate kidney symptoms and usually include: coughing up blood, chest pain, cough, and shortness of breath. Kidney symptoms usually include blood in the urine, protein in the urine, unexplained swelling of limbs or face, high amounts of urea in the blood, and high blood pressure.

Causes Its precise cause is unknown, but an insult to the blood vessels taking blood from and to the lungs is believed to be required to allow the anti-GBM antibodies to come into contact with the alveoli.

Exposure to organic solvents (e.g. chloroform)     or hydrocarbons

Exposure to tobacco smoke

Certain gene mutations (HLA-DR15)

Infection, such as influenza A

Cocaine inhalation

Metal dust inhalation

Bacteraemia

Sepsis

High-oxygen environments

Treatment with anti-lymphocytic

   Asian Institute of Nephrology and Urology (AINU) is the best kidney hospital in India, providing world-class treatment for all your renal problems. AINU hospitals successfully completed 500 robotic surgeries and proven that they are the best kidney transplant hospital in India.

[ainuhitech]

Goodpasture syndrome (GPS) also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture’s antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

 Signs and Symptoms The anti-glomerular basement membrane (GBM) antibodies primarily attack the kidneys and lungs, although, generalised symptoms like malaise, weight loss, fatigue, fever, and chills are also common, as are joint aches and pains

Lung symptoms usually antedate kidney symptoms and usually include: coughing up blood, chest pain, cough, and shortness of breath. Kidney symptoms usually include blood in the urine, protein in the urine, unexplained swelling of limbs or face, high amounts of urea in the blood, and high blood pressure.

Causes Its precise cause is unknown, but an insult to the blood vessels taking blood from and to the lungs is believed to be required to allow the anti-GBM antibodies to come into contact with the alveoli.

Exposure to organic solvents (e.g. chloroform)     or hydrocarbons

Exposure to tobacco smoke

Certain gene mutations (HLA-DR15)

Infection, such as influenza A

Cocaine inhalation

Metal dust inhalation

Bacteraemia

Sepsis

High-oxygen environments

Treatment with anti-lymphocytic

   Asian Institute of Nephrology and Urology (AINU) is the best kidney hospital in India, providing world-class treatment for all your renal problems. AINU hospitals successfully completed 500 robotic surgeries and proven that they are the best kidney transplant hospital in India.

[syndromes-en-blog]

Goodpasture syndrome

"Goodpasture" redirects here. For other uses, see Goodpasture (disambiguation). Goodpasture syndrome (GPS; also known as Goodpasture’s disease, antiglomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture's antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death. It is treated with immunosuppressant drugs such as corticosteroids and cyclophosphamide, and with plasmapheresis, in which the antibodies are removed from the blood. Famous sufferers include Vince Earl, an actor on the British soap opera Brookside, who underwent a successful kidney transplant in 2012. The disease was first described by an American pathologist Ernest Goodpasture of Vanderbilt University, in 1919 and was later named in his honor. More details Android, Windows

[ainubanja]

Goodpasture syndrome (GPS) also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture’s antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

 Signs and Symptoms The anti-glomerular basement membrane (GBM) antibodies primarily attack the kidneys and lungs, although, generalised symptoms like malaise, weight loss, fatigue, fever, and chills are also common, as are joint aches and pains

Lung symptoms usually antedate kidney symptoms and usually include: coughing up blood, chest pain, cough, and shortness of breath. Kidney symptoms usually include blood in the urine, protein in the urine, unexplained swelling of limbs or face, high amounts of urea in the blood, and high blood pressure.

Causes Its precise cause is unknown, but an insult to the blood vessels taking blood from and to the lungs is believed to be required to allow the anti-GBM antibodies to come into contact with the alveoli.

Exposure to organic solvents (e.g. chloroform)     or hydrocarbons

Exposure to tobacco smoke

Certain gene mutations (HLA-DR15)

Infection, such as influenza A

Cocaine inhalation

Metal dust inhalation

Bacteraemia

Sepsis

High-oxygen environments

Treatment with anti-lymphocytic

   Asian Institute of Nephrology and Urology (AINU) is the best kidney hospital in India, providing world-class treatment for all your renal problems. AINU hospitals successfully completed 500 robotic surgeries and proven that they are the best kidney transplant hospital in India.

[ainubanja]

Best Nephrology Hospital in India | Urology | Banjara hills | AINU

Goodpasture syndrome (GPS) also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture’s antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

 Signs and Symptoms The anti-glomerular basement membrane (GBM) antibodies primarily attack the kidneys and lungs, although, generalised symptoms like malaise, weight loss, fatigue, fever, and chills are also common, as are joint aches and pains

Lung symptoms usually antedate kidney symptoms and usually include: coughing up blood, chest pain, cough, and shortness of breath. Kidney symptoms usually include blood in the urine, protein in the urine, unexplained swelling of limbs or face, high amounts of urea in the blood, and high blood pressure.

Causes Its precise cause is unknown, but an insult to the blood vessels taking blood from and to the lungs is believed to be required to allow the anti-GBM antibodies to come into contact with the alveoli.

Exposure to organic solvents (e.g. chloroform)     or hydrocarbons

Exposure to tobacco smoke

Certain gene mutations (HLA-DR15)

Infection, such as influenza A

Cocaine inhalation

Metal dust inhalation

Bacteraemia

Sepsis

High-oxygen environments

Treatment with anti-lymphocytic

   Asian Institute of Nephrology and Urology (AINU) is the best kidney hospital in India, providing world-class treatment for all your renal problems. AINU hospitals successfully completed 500 robotic surgeries and proven that they are the best kidney transplant hospital in India.

[ainudsnr]

Goodpasture syndrome (GPS) also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture’s antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

 Signs and Symptoms The anti-glomerular basement membrane (GBM) antibodies primarily attack the kidneys and lungs, although, generalised symptoms like malaise, weight loss, fatigue, fever, and chills are also common, as are joint aches and pains

Lung symptoms usually antedate kidney symptoms and usually include: coughing up blood, chest pain, cough, and shortness of breath. Kidney symptoms usually include blood in the urine, protein in the urine, unexplained swelling of limbs or face, high amounts of urea in the blood, and high blood pressure.

Causes Its precise cause is unknown, but an insult to the blood vessels taking blood from and to the lungs is believed to be required to allow the anti-GBM antibodies to come into contact with the alveoli.

Exposure to organic solvents (e.g. chloroform)     or hydrocarbons

Exposure to tobacco smoke

Certain gene mutations (HLA-DR15)

Infection, such as influenza A

Cocaine inhalation

Metal dust inhalation

Bacteraemia

Sepsis

High-oxygen environments

Treatment with anti-lymphocytic

   Asian Institute of Nephrology and Urology (AINU) is the best kidney hospital in India, providing world-class treatment for all your renal problems. AINU hospitals successfully completed 500 robotic surgeries and proven that they are the best kidney transplant hospital in India.

[ainudsnr]

Best Nephrology Hospital in India | Urology | Dilsukhnagar | AINU

Goodpasture syndrome (GPS) also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture’s antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

 Signs and Symptoms The anti-glomerular basement membrane (GBM) antibodies primarily attack the kidneys and lungs, although, generalised symptoms like malaise, weight loss, fatigue, fever, and chills are also common, as are joint aches and pains

Lung symptoms usually antedate kidney symptoms and usually include: coughing up blood, chest pain, cough, and shortness of breath. Kidney symptoms usually include blood in the urine, protein in the urine, unexplained swelling of limbs or face, high amounts of urea in the blood, and high blood pressure.

Causes Its precise cause is unknown, but an insult to the blood vessels taking blood from and to the lungs is believed to be required to allow the anti-GBM antibodies to come into contact with the alveoli.

Exposure to organic solvents (e.g. chloroform)     or hydrocarbons

Exposure to tobacco smoke

Certain gene mutations (HLA-DR15)

Infection, such as influenza A

Cocaine inhalation

Metal dust inhalation

Bacteraemia

Sepsis

High-oxygen environments

Treatment with anti-lymphocytic

 Asian Institute of Nephrology and Urology (AINU) is the best kidney hospital in India, providing world-class treatment for all your renal problems. AINU hospitals successfully completed 500 robotic surgeries and proven that they are the best kidney transplant hospital in India.

[ainuhitech]

Goodpasture syndrome (GPS) also known as Goodpasture’s disease, anti-glomerular basement antibody disease, or anti-GBM disease) is a rare autoimmune disease in which antibodies attack the basement membrane in lungs and kidneys, leading to bleeding from the lungs and kidney failure. It is thought to attack the alpha-3 subunit of type IV collagen, which has therefore been referred to as Goodpasture’s antigen. Goodpasture syndrome may quickly result in permanent lung and kidney damage, often leading to death.

 Signs and Symptoms The anti-glomerular basement membrane (GBM) antibodies primarily attack the kidneys and lungs, although, generalised symptoms like malaise, weight loss, fatigue, fever, and chills are also common, as are joint aches and pains

Lung symptoms usually antedate kidney symptoms and usually include: coughing up blood, chest pain, cough, and shortness of breath. Kidney symptoms usually include blood in the urine, protein in the urine, unexplained swelling of limbs or face, high amounts of urea in the blood, and high blood pressure.

Causes Its precise cause is unknown, but an insult to the blood vessels taking blood from and to the lungs is believed to be required to allow the anti-GBM antibodies to come into contact with the alveoli.

Exposure to organic solvents (e.g. chloroform)     or hydrocarbons

Exposure to tobacco smoke

Certain gene mutations (HLA-DR15)

Infection, such as influenza A

Cocaine inhalation

Metal dust inhalation

Bacteraemia

Sepsis

High-oxygen environments

Treatment with anti-lymphocytic

   Asian Institute of Nephrology and Urology (AINU) is the best kidney hospital in India, providing world-class treatment for all your renal problems. AINU hospitals successfully completed 500 robotic surgeries and proven that they are the best kidney transplant hospital in India.