#EndTB

[bassproshopspyramid]

‼️⚠️ 🎉 GOOD NEWS (nov. 15 / 2023)

[image ID: the destiel confession meme. cas says "I love you.

dean replies: "the endTB clinical trial found 3 new all-oral drug regiments with similar efficacy and safety to current conventional treatments while reducing the treatment time by up to two-thirds. they will allow for more individualized treatment centred on patients. and for the first time in the care of multi-drug resistant tuberculosis, these treatments can be used in nearly all cases of MDR-TB, including in children, adolescents, adults, and pregnant people."

end ID.]

multi-drug resistant tuberculosis (MDR-TB) is a form of tuberculosis that is particularly difficult to treat due to resistance to the 2 most powerful firstline antibiotics. many people are still treated with conventional treatments that are long (up to 24 months), ineffective, and often cause terrible side effects.

every year, there are about 500,000 new cases of MDR-TB worldwide - but only a tiny fraction are successfully treated. the endTB trial, led by MSF (médecins sans frontières/doctors without borders), PIH (partners in health) and IRD (interactive research and development), funded by Unitaid, and featuring 754 participants in 7 countries is a randomized, controlled trial designed to provide high-quality evidence on new, all-oral, shortened drug regimens.

one of the new regimens was found to be even more effective than current conventional treatments. the new trial also added an additional 4th regimen as an alternative for people who can’t tolerate some TB drugs.

there are now — for the first time ever! — 5 all-oral regimens that are effective against MDR-TB in 9 months or less and which are as good or better than a contemporary standard-of-care control. if recommended by WHO, they can be used in nearly all cases of MDR-TB, including children, adolescents, adults, and pregnant people, a first in MDR-TB care. two of the non-inferior regimens cost under $400, and a third costs under $600, for the full course of treatment.

EDIT: press release from endTB for a source

[nerdfighternichole]

Make your own John Green Vision Board imgflip.com/i/8bddfw via @imgflip

C'mon Danaher, be the heroes we need!! Nerdfighteria share your vision boards to stop TB by making it #TimeFor5 and #XDRnext! PLEASE help save families from TB! 🙏

[firefly-fez]

Making some art to promote TB awareness.

[motherteresacharitabletrust]

World Tuberculosis Day 2025

World Tuberculosis Day was held at D.N. Rajaratnam Kalaiyarangam, located near Nadigarthilagam Sivaji Memorial Hall in Raja Annamalaipuram, Chennai-600028. Tamil Nadu Health Minister M. Subramaniam participated in the event and delivered a special speech. Mother Teresa Auto Drivers Welfare Association founder Dr. G.K. Dhas also participated in the event. Other attendees included Mother Teresa Peravai advisor Marianathan, Sivajinathan, Richard Reagan, and Auto Drivers Association executives K.V. Sivakumar, Wilsonraj Jagannathan, and Vinoth. The event concluded with the pasting of the Tuberculosis Eradication Sticker on an auto-rickshaw.

Let's unite to end TB!

Join : www.motherteresacharities.org

[historicsaranaclake]

First Steps⁠

by Amy Catania⁠

World TB Day — March 24, 2025⁠

⁠Recently we celebrated the release of a new book by John Green, Everything is Tuberculosis. An award winning author and something of a legend with the younger crowd, John Green has come to share our obsession with TB.

Each HSL staff member read the book in one fell swoop. It is a beautiful, heartbreaking, eye-opening book that challenges us to grasp the enormity that is tuberculosis, past and present. Most Americans are unaware that TB once took the lives of more people in this country than cancer and heart disease combined. Many don’t know that the disease continues to kill more than a million people around the world each year, even though we have the medicine to cure it. 

John Green doesn’t attempt to tell a complete history of TB, and so it is understandable that he skims over an account of Saranac Lake. Of course we would have liked to read about Dr. Edward Livingston Trudeau, a founder of the fresh air sanatorium movement in the United States and pioneer in the scientific research of TB. Dr Trudeau died of the disease in 1915, but Saranac Lake continued to develop as a center for patient care and professional training in the field. Some of the early drug trials were performed here in Saranac Lake in the early 1950s. Today, scientists at Trudeau Institute continue to advance the science of TB and other diseases.

In the 1950s, the antibiotic treatment was perfected at Rutgers University. Although it meant hard times for our local economy, the magic bullet of medicine was celebrated near and far. Indeed, TB is now rare in the United States, thanks to widespread treatment and testing.

It can be tempting to leave the story there, but John Green reminds us that medicine and science do not progress in straight lines. Saranac Lake’s TB history is only one small piece of an ever-evolving narrative. Here we are 75 years later, and the drugs still haven’t made it to places where TB runs rampant. Inequality, broken public health systems, persistent high drug prices, and lack of access to testing and nutrition, all mean that TB continues to be the worst global public health threat facing humanity. Limited access to medicine provides the opportunity for bacteria to mutate and become resistant. Lack of funding for development of new medicines means we have fewer and fewer answers to the ever-evolving germ.

Now, in 2025, the global situation is — unbelievably — worse than the one John Green described when he finished writing his book in 2024. Last month, the US government abruptly cut USAID-funded global health programs. Millions of people undergoing antibiotic treatment suddenly cannot access medicine. It’s a perfect recipe for the evolution of resistant bacteria. If Covid taught us anything it’s that we are all one organism, and bacteria will find their way to every corner of the globe.

TB will continue its rampage until high income countries take the first step, to care about the problem. This is Mr. Green’s main goal with his book, to bridge the empathy gap. To humanize TB, he focuses on one young person in Sierra Leone, Henry Reider, and his courageous battle against drug resistant TB. 

Reading about Henry brought to mind so many patients in Saranac Lake’s past who are a living part of our museum. We tell the story of Gloria Hazard, who died in Saranac Lake before the age of twenty. We talk about Isabel Smith, who cured for over twenty years in bed. And we remember Dr. E. L. Trudeau, “the beloved physician.” A model of empathy and optimism, Trudeau’s story continues to inspire healthcare workers around the world.

Visitors to the museum often teach us about Trudeau’s lasting legacy. In 2017, Drs. Suzhou Zhongyi Fan and Shulan Zhou visited the museum from China with their daughter, Wen. Practicing medicine in China, Wen’s parents had long been inspired by Dr. Trudeau. That afternoon, they visited the cemetery at Paul Smiths, and they left a note on Trudeau’s grave.

Saranac Lake is relevant to the story of TB because our museum is here today, chronicling the lives of patients and the people who cared for them. Learning about the past is a route to compassion, a first step to global understanding. 

We held a book launch party last week for John Green’s new book. It’s no surprise we had a good turnout. We may be way up here in the Adirondack mountains, far from people around the world struggling with TB, but through our history we are connected. It’s a first step.

Amy Catania

Join us at the Saranac Laboratory Museum on World TB Day, March 24th at 6 PM, for a screening of Crash Course’s ‘The Deadliest Infection of All Time.’ In this pre-recorded video lecture, author John Green explores this history, its persistence today, and how understanding TB’s history can point us to a different future. Copies of his recently published book, Everything is Tuberculosis, will be available for purchase.

[chestsurgeon]

Yes! We Can End TB.

On World TB Day (March 24), let's reaffirm our commitment to eliminating tuberculosis, one of the world's deadliest infectious diseases. TB affects millions, causing severe health, social, and economic challenges. With early diagnosis, proper treatment, and awareness, we can stop TB in its tracks! Know the symptoms: Persistent cough, fever, night sweats, and unexplained weight loss.

Get screened: Early detection saves lives. Spread awareness: Together, we can make a difference.

Dr. Pallavi Purwar 📞 Ph: +91 99100 81862 🌐 W: www.chest-surgeon.com Chest Surgeon - Chest Specialist (New Delhi)

[iimtcollege]

On World Tuberculosis Day, let’s unite to raise awareness about the disease and its impact, mobilize efforts towards its eradication, spark action, and inspire hope in the fight against Tuberculosis.

Together, we can end tuberculosis and create a healthier, TB-free future for all!

[globalgenerex]

🌍💫 World Tuberculosis Day 2025 💫🌍

On this World TB Day, we acknowledge the ongoing global battle against Tuberculosis (TB) and emphasize the importance of innovative treatments. At Global Regenex, we are committed to pioneering regenerative medicine, including stem cell therapies, to support the fight against TB and provide hope for those affected.

[viezec]

🌍💡 World Tuberculosis Day 2025 💡🌍

Today, on World TB Day, we bring attention to the global fight against Tuberculosis (TB). At Viezec Medical Tourism, we are committed to connecting patients with world-class healthcare providers and innovative treatments to fight TB and improve health outcomes worldwide.

🔬 Innovative TB Treatments: Through international medical tourism, we provide access to cutting-edge therapies, including stem cell treatments and advanced medical care, to help combat TB and support recovery.

[globalstemcellcare]

World Tuberculosis Day 2025

On this World TB Day, we stand united in the fight against Tuberculosis (TB). At Global Stem Cell Care, we are committed to advancing groundbreaking treatments that aim to combat TB and improve the lives of those affected by it.

🔬 The Future of Treatment: Stem cell research is opening new possibilities for healing and regenerating damaged lungs, providing hope for better TB outcomes.

[digambrapowersolutionindia]

World TB Day

🌿 YES! We Can End TB! 🌿

This World Tuberculosis Day, let's unite to raise awareness, support those affected, and work towards a TB-free world.

Together, we can breathe life into a healthier future. 💪✨

[orthoclinic]

🌍💪 World Tuberculosis Day 2025 💪🌍

Today, we raise awareness about Tuberculosis (TB), a disease that still affects millions worldwide. 🦠 But together, we can make a difference!

✨ TB is preventable and treatable, but it requires global efforts, access to care, and awareness. This year, let’s spread knowledge, reduce stigma, and encourage early detection and treatment.

🔬 Research, solidarity, and action are key to ending TB once and for all. Let’s stand together in the fight against TB! 💚 VENKAT PADMA ORTHO CLINIC Address: VISAKAPATNAM Contact us: 7799607409, 7010420956

[dentalwiresdentalclinic]

World TB Day

🌍World Tuberculosis Day - March 24th Let’s unite to raise awareness about TB and commit to building a healthier, TB-free world. Early detection, proper treatment, and community education are key!

Together, we can make a difference. 💪✨

[svastha-hospitals]

🌍💪 World Tuberculosis Day 2025 💪🌍

Today, we raise awareness about Tuberculosis (TB), a disease that still affects millions worldwide. 🦠 But together, we can make a difference!

✨ TB is preventable and treatable, but it requires global efforts, access to care, and awareness. This year, let’s spread knowledge, reduce stigma, and encourage early detection and treatment.

🔬 Research, solidarity, and action are key to ending TB once and for all. Let’s stand together in the fight against TB! 💚 SVASTHA EMERGENCY AND MULTI SPECIALITY HOSPITAL CONTACT: 9044337799 MANDAPET

[gsuniversityofficial]

On this World Tuberculosis Day, let’s unite to raise awareness and work towards a TB-free world. Together, we can end the stigma, improve access to treatment, and save lives.

At GS University, we stand with global efforts to eliminate TB and promote better healthcare for all.

[anilchemists]

World TB Day 2025

✨ Let’s unite to make a TB-free world! This World Tuberculosis Day, let's spread awareness, encourage early diagnosis, and support treatment. Together, YES! We can end TB!