#Diaspora Human Genomics Institute
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Meharry Medical College and Global Partners Build Largest African Ancestry Genomic Database
Meharry Medical College, in collaboration with Regeneron Genetics Center, AstraZeneca, Novo Nordisk, and Roche, has launched an initiative to create the world’s largest genomic database of individuals with African ancestry. The project aims to collect genetic material from 500,000 participants to develop a new reference genome that better represents Black populations, potentially leading to…
#African ancestry#anonymous data#AstraZeneca#diagnostic tests#Diaspora Human Genomics Institute#genetic material#genetic research#genomic database#grant program.#HBCUs#health disparities#medicine development#Meharry Medical College#Novo Nordisk#pharmaceutical companies#reference genome#Regeneron Genetics Center#research collaboration#Roche#STEM education#underrepresentation
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US bid to attract talent: Opening statement at the subcommittee hearing - Times of India
New Post has been published on https://uspost.xyz/us-bid-to-attract-talent-opening-statement-at-the-subcommittee-hearing-times-of-india/
US bid to attract talent: Opening statement at the subcommittee hearing - Times of India
MUMBAI: Part 1: A group of US lawmakers recently held a hearing titled – ‘Oh, Canada! How outdated US immigration policies push top talent to other countries.’ The aim of this subcommittee on Immigration and Citizenship, was to understand how Canada’s immigration laws and procedures are helping it to attract top talent, these learnings in turn could perhaps spur the necessary immigration reforms in the US. Soon after Joe Biden was sworn in as President – one of the first steps announced was the presentation of a comprehensive immigration reform legislative package to the Congress. While several steps have been taken to strengthen the legal immigration system, there has till date been no major legislative reform. Read also: https://timesofindia.indiatimes.com/world/us/biden-reforms-on-day-1-set-to-cheer-indian-diaspora/articleshow/80377087.cms “With today’s hearing, we explore the harmful effects that our antiquated immigration system has had on our ability to compete in the global race for talent, particularly in relation to Canada,” was the opening statement by House judiciary committee chairman, Jerrold Nadler. “A diverse talent base that includes the best and brightest minds from around the world is critical to strengthening our STEM advantage, and by extension—our national security interests. Toward that end, I note that the bipartisan National Security Commission on Artificial Intelligence calls immigration reform a national security imperative.” “The last time any significant changes were made to our immigration laws was in 1990. Back then, most of us were not using the internet, and cell phones had yet to be mass-produced. Things like text messaging and grid computing—which paved the way for cloud computing—had not even been invented. The Human Genome Project was launched but our understanding of the role that genes play in disease causation was only just beginning,” he added. “Things that we take for granted today were the stuff of science fiction 30 years ago. And yet today, we remain bound by an immigration system that is frozen in another era. Without reforms, there is no doubt that we will lose top scientific talent and innovators to both allies and adversaries with modernized systems,” he continued. Indian professionals, including highly-skilled workers in the STEM field can well relate to Nadler’s following statement. “First, temporary visa options for highly skilled workers are quite limited. Visas are available to individuals who have already risen to the very top of their fields, as well as those who are transferring from an overseas company to a US affiliate. But graduates of US universities—including those with master’s and Ph.D. degrees—who wish to start their STEM careers here must often compete with thousands of others for one of a limited number of ‘specialty occupation’ visas.” (This refers to H-1B visas). “Those who are fortunate enough to beat the odds and obtain a temporary visa, face other obstacles if their employer wishes to sponsor them for permanent residence. As a result of annual caps on employment-based visas, many are forced to wait years—and in some cases decades—for an immigrant visa to become available.” (TOI has often quoted a CATO Institute study. According to David J Bier, Immigration Policy Analyst at this think-tank the employment based green card backlog (EB2 and EB3 skilled category) for those from India had reached 7.41 lakh in April 2020, with an expected wait time of 84 years ). Nadler remarked that many immigrants who would otherwise pursue the American dream are now turning to other countries – notably Canada, which has made significant strides in building flexibility and incentives into their immigration system to attract skilled professionals to their shores. “Programs like Express Entry, the Start-Up Visa, and the Global Talent Stream have proven so successful that those who have been failed by the US immigration system are now turning to Canada. Ironically, Canada’s successful Start-Up Visa Program was inspired by legislation introduced in the House in 2011 that never became law. The results are paying off, with Toronto earning the moniker—the ‘Silicon Valley of the North,’ he stated. “It is my hope that with this hearing, we can begin to build some consensus on reforms that are needed to ensure that our immigration system works for—not against—the American people,” summed up Nadler. In a series of articles, TOI will bring to you excerpts of suggestions made by some of the witnesses called for the hearing and by other experts who gave their written submissions.
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As a descendant of white Anglo-Saxon ancestry who came over before the founding of our nation and having been able to trace my ancestry back to the 1600s, I was SHOCKED, DISMAYED and SADDENED to find that my ancestors owned slaves through there WILLS and DEEDS. After discovering this I have wondered what happened to those families and individuals and how I COULD HELP them discover their own ancestry.
Many of my ancestors settled on the East Coast of Virginia, upper coast of North Carolina and the coast of South Carolina including many in and around Marion, SC. They were mostly farmers(plantation owners), clergy, doctors and some were endentured who had to work for their passage and eventually given land by England.
For those of African-American lineage who are wanting to discover their roots and ancestry this is an excellent article. I highly recommend reading and especially important to watch the 4 videos. This history of SLAVERY, RECONSTRUCTION and JIM CROW MUST NOT BE FORGOTTEN and we MUST somehow RECONCILE our PAINFUL PAST in order to HEAL our NATION.
LOST LINEAGE: THE QUEST TO IDENTIFY BLACK AMERICANS ’ ROOTS
By NICOLE ELLIS | Published February 25 at 11:11 AM ET | Washington Post | Posted February 26, 2020 | 4 VIDEOS |
For many Americans, blended ancestry is an integral part of their identity. The mosaic of hyphenated heritages preserves cultural connections beyond the United States, lineages that build pride and a sense of belonging. But for Americans descended from enslaved Africans, the roots of their ancestry are often a mystery. Family trees go dark after five or six generations, a reminder that 150 years ago, black people weren’t considered people.
Genealogists refer to this as “the brick wall,” an obstruction in African American lineage that dates to 1870 when the federal Census began recording African descendants — 250 years after they were first hauled in chains to what would become the United States.
Before then, their lives existed on paper only as another person’s property. To penetrate the brick wall, black Americans frequently must rely on the names of their ancestors’ owners.
“You can find them through [their owners’] tax records, estate records, slave schedules and wills,” said Mary Elliott, the “Slavery and Freedom” curator for the National Museum of African American History and Culture.
Even after abolition, the black experience has fallen victim to campaigns that obscure the darkest parts of the American story, diminishing African Americans’ connections to their pasts and warping the collective memory of the nation’s history.
But in recent years, black Americans have pursued new efforts to uncover their stories. From exploring sunken vessels of the Middle Passage to reconstructing museum exhibits that chronicle slavery, African Americans are breaking down the barriers that separate them from their ancestors and reconnecting with a lineage once lost.
EPISODE 1: AMERICA’S LAST KNOWN SLAVE SHIP
Unlike most descendants of enslaved people, the residents of Africatown — a predominantly black community in Mobile, Ala. — know their ancestors’ stories.
They were carried from the West African nation of Benin in an illegal smuggling expedition financed by wealthy American businessman Timothy Meaher in 1860, decades after the transatlantic slave trade was abolished. The schooner that carried the enslaved Africans, called the Clotilda, is considered America’s last known slave ship.
As an artifact of American history, the Clotilda was lost for generations. The captain had set fire to the vessel to avoid detection, causing it to sink into the Mobile River. The shackled Africans released onshore became the founders of Africatown.
For generations, the lost ship left a hole in the story of the historical community. But the Clotilda’s discovery in August revealed the enslavers’ actions and highlighted the perseverance of the people onboard, giving their descendants a sense of validation and clarity that few descendants of slaves in America have experienced.
EPISODE 2: DIVING WITH A PURPOSE
Despite incredible strides, genealogical research falls short in connecting American descendants of slavery with the African communities from which their ancestors were taken.
European colonizers transported an estimated 12.5 million Africans across the Atlantic Ocean between 1525 and 1866, according to the trans-Atlantic Slave Trade Database. Enslaved Africans were stripped of identities and shipped as though they were textiles, wheat or other cargo.
“It was a business,” said Elliott of the National Museum of African American History and Culture. “You won’t see many names documented, but you’ll see numbers. You’ll see gender. You’ll see age.”
As the international slave trade was outlawed in the early 19th century, many slave ships were repurposed for piracy, leaving little evidence of their former lives as vessels for human cargo. Of the more than 10,000 slave ships that made voyages during the transatlantic slave trade, only five have been identified worldwide. Archaeologists and scholars suspect thousands more dot coastlines beneath the surface.
Among those searching for the vessels of the Middle Passage is a group of teenagers working with Diving With a Purpose, an international organization dedicated to preserving the heritage of the African diaspora lost to the oceans’ depths. Their quest is focused on the Guerrero, an illegal slave ship that crashed along the coral reef off the coast of Florida in 1827.
The teens, many of them black, say the project has helped them connect with a history that is limited in textbooks.
“It makes me feel more connected to my past ancestors than what any history class has ever taught me,” said 18-year-old diver Michaela Strong.
EPISODE 3: THE GENETICS OF RACE
Scientific advances in human genetics have largely prioritized the biology of people with European ancestry. The endeavor reached a low point with the rise of the eugenics movement, leading to many scientific and statistical methods that continue to be used today. In modern classrooms, the work of eugenicists is often divorced from its origins and motivations, presented as morally neutral. Many scholars argue that eugenicists’ efforts to prove what they already believed — that humans can be bred into a superior race — have hindered understanding of the diversity of the human genome.
These concerns were pivotal in 1991, when more than 15,000 intact human remains were discovered in Lower Manhattan during excavation for a federal office building. Geneticists at Howard University realized that traditional research methods were falling short in identifying remains in the African burial ground, which dated to the 17th and 18th centuries, when African descendants were still enslaved in New York City.
Sequencing the human genome has offered new opportunities to bridge the Middle Passage with DNA. By sequencing genetic traits and overlaying them with ecological environments where they are most prevalent, geneticists have tried to pinpoint the geographic origins of people unfamiliar with their ancestry.
Today, genetic banks are being built throughout Africa to correct course, but work remains in the effort to pinpoint the origins of black Americans.
EPISODE 4: THE LOST CAUSE
One of the most successful propaganda campaigns in American history was developed to obscure the role of slavery in the Civil War. The Lost Cause narrative, perpetuated by groups sympathetic to the Confederate effort, asserted the war was fought over states’ rights and downplayed slavery as the defining “right” in dispute.
The Lost Cause narrative was fueled by popular films and strengthened by Confederate monuments erected across the country. It influenced depictions of slavery in school textbooks, mollifying the brutality of plantation culture and characterizing enslaved Africans as loyal to white Southern families.
Efforts to unravel the influence of the Lost Cause have proliferated in recent years, including in the former Confederate capital of Richmond. In 2013, the Museum of the Confederacy — an institution created as a shrine to the Lost Cause — merged with the American Civil War Museum and reframed the narrative around the Confederate artifacts on display. The reshaped exhibits clarified the role slavery played in America’s development, the war’s outbreak and the racial tensions that followed.
Christy Coleman, former chief executive of the American Civil War Museum, says Americans carry around the legacies of slavery every day.
“The only way that you really can come to some form of conciliatory behavior is when everybody finally understands it,” Coleman said.
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Page design by Nina Wescott. Graphics by Brian Monroe. Video producing by Nicole Ellis and Ross Godwin.
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2019 Arkansas Times Academic All-Star Team
The 2019 Arkansas Times Academic All-Star Team, the 25th team the Times has honored, is made up of coders, musicians, scientists and championship athletes. There's rarely a B on the transcripts of these students in not just this, their senior year, but in any year of their high school careers.
Back in 1995, the Times created the Academic All-Star Team to spotlight what we then called "the silent majority — the kids who go to school, do their homework (most of it, anyway), graduate and go on to be contributing members of society." Too often, we argued then, all Arkansans heard about young people was how poorly they were faring. Or, when students did get positive attention, it came for athletic achievement.
As you read profiles of this year's All-Stars, it should be abundantly clear that good things are happening in Arkansas schools and there are many academic achievers who deserve to be celebrated. You should get a good idea, too, of how these stellar students are busy outside school, with extracurricular activities, volunteer work, mission activities and more.
They'll be honored April 26 at a ceremony at UA Little Rock's new River Market campus with plaques and cash awards.
Many college plans listed here are not set in stone, as students await information on scholarships and acceptances.
MOHAMMED ABUELEM Age: 16 Hometown: Little Rock High School: Pulaski Academy Parents: Tarek Abuelem and Shireen Khalaf College plans: Harvard University
What accomplishments can a 16-year-old lay claim to? Mohammed Abuelem has earned prizes in competitions in science, essay writing, History Day projects, Spanish, math. He's studied DNA sequencing at Harvard; researched the effect of radiation on soybeans; aced all his classes at Pulaski Academy. But this teenager, two years younger than his classmates and fluent in Arabic, can also point to work with Syrian refugees in camps in Jordan for two summers running. After his sophomore year, Mohammed volunteered at the Zaatari refugee camp in the northern part of Jordan, where 60,000 people have taken refuge. There, he interviewed families and visited the medical clinics. He listened "to their stories and how their life is at the camp. ... I got the chance to see how medicine is practiced toward people who are part of a diaspora." He returned to Jordan after his junior year and distributed food and supplies to Syrian refugee families in the capital, Amman. "So many of the refugees are relocated toward urban areas, and don't get as many benefits" as those in the camps, Mohammed said. Mohammed decided to bring the lessons of the crisis home: "I wanted to involve local people here." So, he organized a benefit piano recital where he and others played (he performed a piece by the Greek composer Yanni) and raised $5,000 from the audience. Half the sum went to the Syrian Emergency Task Force and the other half to his Boy Scout Eagle project, building first-aid and hygiene kits for Syrian refugees. Because the Middle East is his passion, his senior thesis (in an elective class at Pulaski Academy) is on the Arab Spring and, because he is fluent, he was able to use primary sources in Arabic. As he heads to college, Mohammed is unsure of exactly where he'll put his considerable brain power to work. Though keen on many subjects, Mohammed's favorite is biology. His father, a neurosurgeon at CHI St. Vincent Infirmary, "has emphasized that he wants me to choose the right path for me," rather than mirror his father's career, Mohammed said.
CHLOE BOWEN Age: 18 Hometown: Fayetteville High School: Springdale High School Parents: Yancey and Ginger Bowen College plans: University of Arkansas at Fayetteville or University of Alabama
The last thing most high school students want to do just a few weeks before the start of their senior year is switch schools. For Chloe Bowen, though, the decision to transfer from Fayetteville High School, where she'd gone since ninth grade, to Springdale High School for her final year wasn't particularly difficult. Many of her friends had already graduated, and Chloe's burgeoning interest in engineering drew her to Springdale High's Engineering and Architecture Academy. "I was ready for a change — [a] new challenge," she said. She's certainly found it. Chloe signed up for four engineering classes, one of which has her working with a group of engineering students from the University of Arkansas to design a device that will allow one of Chloe's classmates, who has cerebral palsy and uses a wheelchair, to walk across the stage at graduation. "Getting to collaborate with them has been a really great experience," she said. Chloe traces her interest in engineering to a human geography class she took in ninth grade, where she learned about urban development and city planning. She's not sure what type of engineering she'll settle on — for now, it's all about exploration and learning about a career that will draw on both her math-loving analytical side and her artistic interests. Chloe has flourished in Springdale's engineering and architecture academy. She's a National Merit Finalist, ranked first in her class with a 4.27 GPA, and she's developed a tight-knit group of new friends who share her interests. She recently helped run a STEM day for younger students and has represented the engineering and architecture academy at area junior highs.
Chloe is also active in her church youth group and has a part-time job working in another church's nursery. That doesn't leave much time for other hobbies. "I used to play volleyball, but I don't anymore," she said. "I've been pretty busy with homework and projects lately."
JORDAN ERICKSON Age: 18 Hometown: Hot Springs High School: Lake Hamilton High School Parent: Mandy Farmer College plans: Baylor University
Jordan Erickson is the big man on Lake Hamilton High School's campus. He's the class president, the valedictorian and a National Merit Semifinalist. He's also 6-foot-10 and was the captain of the basketball team, which went 25-3 and won its conference. "It meant a lot [to be captain] because I'd been playing basketball with these guys since fifth grade," Jordan said. While this season marks the end of his basketball career, look for him in pick-up games at Baylor University, where he'll be a University Scholar, a competitive program that generally accepts fewer than 2 percent of incoming Baylor students. The Scholars program will allow him to pursue an individualized course of study. Jordan is planning on studying one area in science, likely biology, and one in the humanities, likely Spanish. He plans to be a doctor and figures that knowing Spanish could be beneficial. He doesn't know what sort of doctor he wants to be, but has gotten some experience working with seniors with neurodegenerative diseases as a volunteer with The Caring Place, a day center for patients suffering from Alzheimer's and dementia. "The people there were just absolutely loving and caring, the staff as well as the patients," he said. "It was heartwarming and heartbreaking as well." Jordan's mom, Mandy Farmer, is a nurse practitioner. He resisted following in her footsteps for years, he said, but as he's gotten older he's realized what an inspiration she's been. She instilled in him a motto that he's obviously applied: "There is no penalty for overachievement."
KATE FREYALDENHOVEN Age: 18 Hometown: Conway High School: Conway High School Parents: Tim and Mary Ann Freyaldenhoven College plans: Rhodes College in Memphis
Kate Freyaldenhoven is competitive. Ranked second in her class at Conway High School, she said she was driven to "achieve the highest grades" in all her courses by the same ambition that earned her spots on the school's varsity cross-country and track teams. She has a 4.42 grade point average, and she said it's this "kind of tenacity" that earned her the perfect score of a 36 on the ACT. After two attempts that earned her a 33 and a 34, Kate said, "I pushed myself to do the best that I can do, and I'm very glad that I took it again." She's taking this tenacity to Rhodes College in Memphis, where she recently signed to run on its cross-country and track and field team. Kate said she decided on Rhodes because she knew she wanted to run in college, but her education was most important, and she wanted to go to a school that "was great with balancing academics and athletics." She said Rhodes felt like a "great fit" for her, and she'll be able to grow "not only as a student, but as an athlete." Another crucial part of her decision to attend Rhodes is the "plethora" of community service organizations the school offers. Kate said that as a kid, her mother took her along when doing service work for nonprofits, and since then, volunteering has been "a really big part of my life." Two summers ago, Kate also participated in the Community Health Applied in Medical Public Service program at Conway Regional Hospital, where she "witnessed firsthand different aspects of working in the medical field." She said she's interested in pursuing a medical career, perhaps as a physician, so she can use her "passion for science and math to contribute something beneficial." Kate said she's looking forward to research and internship opportunities in Memphis and to the "close-knit community" she said she felt on Rhodes' campus.
MARY JIA Age: 17 Hometown: Stuttgart High School: Arkansas School for Mathematics, Sciences and the Arts Parents: Melissa and Yulin Jia College plans: Undecided
Mary Jia knows what she wants to do, and what she wants to do is study rice. "Rice is so amazing!" she said, with an enthusiasm so genuine she'll make you excited about rice, too. She said it's a model genome to study in plant science, and she's particularly interested in the "biological sciences and the numerology behind rice." Mary has applied to 16 different schools, but her top choice is the California Institute of Technology, where her favorite physicist, Sean M. Carroll, works as a professor. She said she plans on studying rice by pursuing an M.D.-Ph.D., a combined doctorate of medicine and philosophy, which can take between seven and nine years to complete. "With an M.D., you learn a little bit of everything, which is basically my goal in life," Mary said. "And a Ph.D. is more specific." Mary's research at the Harry K. Dupree Stuttgart National Aquaculture Research Center earned her a semifinalist spot in the Regeneron Science Talent Search. She's the only finalist from Arkansas. Her project studied the blast disease resistance of three strains of rice, a process through which Mary said she hopes to find "resistance genes" to help keep farmers from having to use fungicides on their rice crops. During a recent trip to visit family in China, Mary was able to appreciate the opportunities she's had to study her passion. "I really want my family to one day be able to enjoy the same things that I do, to go out in the world and realize they can be whatever they want," she said. Ranked No. 1 in her class at Arkansas School for Mathematics, Sciences and the Arts, Mary is also a member of the school's Grandma Club, which teaches "relaxing" skills such as knitting — Mary's specialty — and origami to the "future grandmas of America."
ISABELLE FLORENCE JONES Age: 18 Hometown: Jonesboro High School: The Academies at Jonesboro High School Parents: Robert and Mary Kay Jones College plans: Boston College
Isabelle Jones has been called "Dizzy Izzy" since she was a little girl, thanks to the energy she displayed in trying to keep up with her two big sisters. But Izzy, as she likes to be called, could also be called "Busy Izzy" because of the many school leadership positions she holds — student council president, National Honor Society treasurer, Spanish Honor Society president, to name a few — and other academic honors. She's No. 1 in her class. She swims, she runs cross-country. She volunteers at St. Bernards Hospital and the Hispanic Center. She's known, she said, as "that liberal person" at school because of her progressive views on gun control. Izzy said the most significant achievement of her high school career was organizing, as head of the local Students Demand Action chapter, the March for Our Lives last year. Calling "Show me what democracy looks like!" into her bullhorn, Izzy and other organizers led 200 people from Jonesboro High to the courthouse. The speakers included a survivor of Jonesboro's Westside Middle School shooting in 1998, in which two boys shot and killed five people and injured 10 others. Izzy spoke, too, about those who would shift the conversation away from guns and onto mental illness. "I spoke to the fact that someone who suffers from mental illness is more likely to be a victim" of gun violence than to cause it, she said. "People use it as a scapegoat." Because the Students Demand Action members were too young to get a permit for the march, the local Moms Demand Action helped out. "The Moms were so amazing; they let us take control of what we wanted to say," Izzy said. If you are an activist in a "big city," Izzy said, you can "talk to your elected officials and not get the door shut in your face. Here, to talk about gun control, it's a nonstarter, because people think it means you're going to take their guns away." So, Izzy's group focuses on having a community presence, participating in fairs and writing letters. Izzy is ready for big-city life and wants to pursue studies in global health, which is why she applied early decision to Boston College, which plans to offer a major in the field. Boston College has offered Izzy a Gabelli Presidential Scholars scholarship, which is a full-tuition award and goes to only 15 incoming freshmen every year. After college, the plan is med school and, someday, travel to help people in need of medical care with Doctors Without Borders.
JEREMIA LO Age: 18 Hometown: Fayetteville High School: Fayetteville High School Parents: Hsiaowen Cho and Wenjuo Lo College plans: Undecided
Jeremia Lo found her high school niche with Connotations, Fayetteville High School's annual literary magazine, where she serves as design director. When she joined the staff as a junior, she discovered a community of people who enjoy writing, art and photography as much as she does. Digital art has been a passion ever since her dad installed Adobe Photoshop on the family's computer when she was 10 years old. "Years of practice — setting aside time on the weekends to do photostudies and learn color theory — eventually turned jagged lines and irregular proportions into realistic portrayals of faces and creatures," Jeremia wrote in her Academic All-Stars essay. "Via the versatility of digital art — a medium that easily allows me to dabble in design, animation and drawing — I've been able to practice my communication skills by analyzing how details and the big picture work together to convey meaning to viewers." In the short run, thanks to those skills, she's made some spending money doing commissioned portraits and seen the designs for clubs and classes that show up all over the school. Longer term, she's considering a career in UI/UX (user interface/experience) design. To that end, she's planning on majoring in cognitive science or psychology to help her think about how people process design. But art isn't her only passion. While maintaining a 4.37 GPA and a No. 1 rank in her senior class of more than 500 students, she also found time to serve as publicist for the World Language Club and to co-found the Fayetteville High School History Club, realizing "that there are many important events in history that are often overlooked in our curriculum." She grew up in a Mandarin-speaking family, has taken five years of German and is studying Japanese on her own. Spanish, French and Korean are on her to-learn list.
TYLER MERREIGHN Age: 17 Hometown: Greenwood High school: Greenwood High School Parents: Ty and Josie Merreighn College plans: Undecided
When Tyler Merreighn auditioned for "Jeopardy!" last summer, he was coming in with over seven years of trivia experience: He's been on a Quiz Bowl team since he was in third grade. He's now captain of Greenwood High School's team, and in 2018 he led it to a second-place finish at the 6A Arkansas Governor's Quiz Bowl Association. While he didn't make the final cut for the game show, he said he would definitely try out again, and next time he'll be "a little more prepared." He'll have to find time to do that while majoring in biomedical engineering on a pre-med path. He hopes to attend the University of Arkansas at Fayetteville, where he's applied for the prestigious Bodenhamer Fellowship, which awards a select group of students $70,000 scholarships over the course of their education. During an educational trip to Peru with his high school in the summer of 2017, Tyler said he visited a community in Cusco and loved "seeing [the children's] faces light up when you could do something so simple for them," like playing a game of soccer. This experience helped him realize that "whatever I do, I definitely want to be able to help people." Last summer he attended the two-week Medical Applications for Science and Health program at Baptist Health in Fort Smith. MASH requires participants to complete 40 hours a week of shadowing in a hospital. Tyler said the experience affirmed his desire to become a physician, as he "really loved the atmosphere of the hospital." He took the ACT seven times in order to get a perfect score because "I just felt like I could do it, and if I didn't get [a perfect score], then I just felt like I was letting myself down."
KENDON MOLINE Age: 17 Hometown: Conway High School: Conway High School Parents: Rebekkah and Corey Moline College plans: Brigham Young University
Kendon Moline said he has always liked learning how things are built, and as a child, he once spent an entire afternoon watching his neighbors get a new roof installed. A self-described "musician, math nerd, bowler and engineer," he's now third in his class at Conway High School and plans to attend Brigham Young University in Provo, Utah, in the fall to study civil engineering. He's particularly interested in transportation planning, so civil engineering "falls right in line" with that passion. Kendon is so interested in engineering that he received the top possible score on his AP Physics C exam — a class his high school doesn't even offer. While he said he's "not the best at studying," he put in "a lot of effort" for the test because "if it's something you're passionate about, you'll commit to it." Kendon is also committed to his faith, as he'll only be attending BYU for a semester before he leaves to take part in his two-year mission as a member of The Church of Jesus Christ of Latter-day Saints. He's looking forward to his mission, during which he'll be able to "share my beliefs, the Gospel, to help others and to grow." While many young men begin their missions immediately after high school, his parents encouraged him to do a semester of school first in order to "get out of the house and be more independent," so he's not "too shocked" when he does venture out on his own. He said he plans on returning to school after his mission. Kendon also plays the trombone in his school's marching band, bowls for the school team and is working toward earning his Eagle Scout badge.
ANNA OPPENHEIM Age: 18 Hometown: Jonesboro High School: Bay High School Parents: Tim and Lisa Oppenheim College plans: Columbia University
A conscientious leader, Anna Oppenheim uses her voice to make fellow Bay High School students heard. Her community-driven work ethic has come through in her service as student council president and senior class president. She's also used her voice as editor of the school newspaper to connect students and tell their unique stories, such as the feature she wrote about an eighth-grade boy who rescued his family — including his young siblings and stepmother, who had a broken leg — from their burning house. As a learner, Anna has always been interested in taking things apart and reassembling them. As a child, she was fascinated with the human skeleton and memorized every bone. "I know that sounds weird," she said. But her natural aptitude for science and medicine blossomed at an orthopedic surgery program through the Perry Initiative for women in medicine, where she performed a mock orthopedic surgery. After being handed a bone model, a bone saw and a few screws and rods, she was told to break the bone model, then figure out how to put it back together. Anna credits her success in that orthopedic exercise to her background in art, explaining that her artistic disposition helped her creatively place the rods and screws into the bones. Anna hopes to become a doctor, but said art will always be a part of her life. "Throughout my life, art has been a unifying thread, and I never want that passion to die," she said. She's auctioned her artwork to benefit various charities, like the Northeast Humane Society, the American Heart Association and the St. Bernards Health and Wellness Institute.
FELIPE MORALES OSORIO Age: 18 Hometown: Little Rock High School: Parkview Arts and Science Magnet High School Parents: Felipe and Norma Morales College plans: Undecided
Felipe Morales Osorio has a knack for learning on his own. He taught himself pre-calculus, so he could skip straight to calculus. When his world history teacher became ill and had to leave the class mid-year, he worked on the subject independently to earn a 4 (out of 5) on the World History AP exam, meaning he's likely to receive college credit for the course. He's made a habit of turning to Khan Academy, the online collection of free academic courses, to augment or supplement his studies, and it shows: He has a 4.42 GPA and is No. 1 in his class at Parkview. Perhaps his proudest learning achievement came during a Central Arkansas Library System JavaScript coding class he took when he was 12, considerably younger than most of his classmates. He struggled, but studied hard and by the end of the summer he'd created a small version of the original Nintendo "Legend of Zelda" game. He's done grander coding projects since then, but the flash drive that stores that game sits on his bedside table as a reminder of what dedication and perseverance can mean. Felipe is considering computer science as a career path, but he's been leaning toward becoming a research mathematician. "I think math is very beautiful," he said. "There's math everywhere around us. It's in the weather. It's in the seashells. It's in almost everything. It's useful in a wide variety of fields. Science is always changing. But in math, it's more concrete and more absolute. When you prove something, like a theorem, you're proving it using logical arguments. Once you prove it, it's absolute. That really appeals to me, that it has a solid foundation."
JACKSON PARKER Age: 18 Hometown: Paragould High School: Paragould High School Parents: Melanie Parker and Jonathan Lane College plans: University of Arkansas at Fayetteville or Yale University, undecided
Jackson Parker speaks in a measured and self-assured tone that usually only comes with older age. He's good under pressure, evidenced by his many performance-based academic accolades, including scoring a perfect 36 on the ACT, winning the Arkansas State Spelling Bee in 2015, and earning Most Valuable Player in the Arkansas State Quiz Bowl in 2016. Concentrating for long stretches of time will serve him well as a heart surgeon, which he hopes to become one day. "I like the hands-on approach of surgery," he explained. It's an approach Parker has taken to further many of his interests, including his favorite subject, chemistry (he's an alumnus of the summer health program at the University of Arkansas for Medical Sciences); music (he plays flute in the high school band and is a student of music theory), fine art (he draws inspiration from 19th century American landscape painter Thomas Cole) and architecture (American Gothic is his favorite style). "I want to apply myself toward everything I care about like a true Renaissance man," Parker said, adding a personal philosophical view that the arts and sciences, when paired, are fundamental to "understanding the greater physics of the universe." He is a burgeoning Renaissance humanist: While many high school students would rather follow the norm, at least socially and politically, Parker doesn't hesitate to sit at the empty table. Inspired by his grandmother, he's been active with the Greene County Democratic Party, which is so small, Parker said, "it can be hard to feel like you're making a difference." He continues to volunteer with the party because "it's important to start somewhere. You need to have the other side of the moral compass present." In fact, Parker expects to have a career in politics in some way, although he's not sure how. He just knows that "politics affect our lives daily, and if we want our problems to be solved, we have to play an active role."
NOAH BLAKE RABY Age: 18 Hometown: Newport High School: Arkansas School for Mathematics, Sciences and the Arts Parents: Jennifer Raby, Angela Lawson and the late Jerry Raby College plans: Massachusetts Institute of Technology
Last summer, Noah Raby spent six weeks in Chengdu, China, as part of a National Security Language Initiative for Youth program. He'd decided to take Mandarin at the Arkansas School for Mathematics, Sciences and the Arts because, of all the foreign language options, it was the one he "was most uncomfortable with." That willingness to throw himself into the unfamiliar served him well while living with his host family and being served rabbit skull, with its brain, tongue and tendons that hold the jaw to the rest of skull still intact. "Despite how disgusting that might sound, it was actually pretty good," Noah said. Still, eating in the famously piquant Sichuan province wasn't a picnic for Noah, who describes himself as "not really a man of spiciness." Noah plans on minoring in Mandarin at M.I.T. while he's majoring in computer science. The combo could allow him to score a computer-engineering job with a Chinese company down the line. He got his love for computers from his late father, Jerry Raby, a longtime cable installer for Suddenlink who died of cancer just before Noah enrolled in the ASMSA. Noah remembers spending weekends with his dad working on tech projects: fixing a broken Xbox, making flammable thermite from material they bought on eBay, and doing various computer science projects. Noah built his first computer at age 11. His computer-related innovations have made an impact on ASMSA. His science fair project on texturizing ceramic additive manufacturing inspired the school to buy its own ceramic 3D printer.
ADAM SIWIEC Age: 17 Hometown: Rogers High School: Rogers Heritage High School Parents: Ashley and Tomek Siwiec College plans: Stanford University or University of Arkansas at Fayetteville
Adam Siwiec knows there's power in language. When he sits at a computer, coding language lets him create websites, software testing metrics and a laundry list of other things most of us have never heard of. When he sits at his typewriter, though, the language of poetry lets him explore a whole other world — where nature, consciousness and inner reflection dominate the landscape. Adam has pursued both languages with an ambitious determination. He's a National Merit Semifinalist, ranked first in his class, is the All-State Programming Champion, placed second at the University of Arkansas Hackathon and founded his school's computer science club. He's also self-published two books of poetry, the most recent through Amazon's publishing service. "That was a really big deal for me," he said. "I got a box of a hundred books with my name on it sent to my door, and I didn't know what to do with them. So I started handing them out, then selling them. That was fun, adding in the business side of it, too." After he read an article about internet censorship in China, he combined his two interests to create a website that pulled in the poems he had published on Instagram so that people in China, who are not allowed access to the social media site, could read his poetry. Adam plans to study computer science in college and minor in creative writing. He already has some professional coding experience under his belt from spending last summer in Poland working with his uncle's digital services agency. "I think that being a writer, it's really hard to succeed if you're not a New York Times bestseller," he said. "I really want to work for a large company like Google or Apple and do poetry as a hobby."
CLAUDIA SMITH Age: 18 Hometown: Little Rock High School: eStem Public Charter School Parents: Will and Sara Smith College plans: University of Arkansas at Fayetteville
Finding a balance between academic priorities and sports can be tricky, but Claudia Smith manages to do this and advocate for her fellow students at eStem Public Charter School. In addition to competing on the school's soccer and cross-country teams, Claudia and a friend started the Gender and Sexuality Alliance during their junior year at eStem. She did so because she wanted to "have a place for people to meet and feel like they had friends that are facing the same kinds of problems" as they are. The Alliance also works to help the community: It recently finished raising $400 for Lucie's Place, a nonprofit that provides resources and housing for homeless LGBTQ youth. No. 1 in her graduating class, Claudia is heading to the University of Arkansas at Fayetteville this fall, where she plans to study engineering. While she's "really into math" and it's her favorite subject in school, she said the engineering program will allow her to do more "hands-on" work. Because eStem is a small school, she's looking forward to being on the UA's large campus with "a wider variety of people and opportunities to pursue [that] will give me more to get involved in." Claudia said she recently took a tour of the campus and was told that the school has several noncompetitive running groups, which she plans to join to keep her cross-country skills up to speed. She said her interest in politics will travel with her to Fayetteville, and she looks forward to getting involved with social justice organizations on campus.
CHASE MARIE SWINTON Age: 17 Hometown: Sherwood High School: Sylvan Hills High School Parents: Rick and Germaine Swinton College plans: Considering Vanderbilt University
Chase Swinton, who plans on studying neuroscience in college, has gotten just about as much hands-on experience in the field possible for a high school student. She learned about neurodegeneration in a project-based learning summer class at Washington University in St. Louis during the summer after her sophomore year. Last summer, she interned with Dr. Antiño Allen at the University of Arkansas for Medical Sciences, working on NASA-funded research concerning "oxygen space radiation affecting hippocampal-dependent memory and cognitive function," as she described it in her All-Stars essay. In October, she was accepted to attend the Harvard Science Research Conference, where she learned about "computational advances in axon and neuron imaging." She's usually been the only African-American girl in such groups. That can be "difficult and lonely and isolating," she said, but as co-chair of the Principal's Council, a group that mentors middle school students, Sylvan Hills' valedictorian has gotten the chance to be an example for younger black female students. "One of my favorite sayings is 'representation begets representation.' If I'm a model for you, you'll be a model for someone else, and they'll be a model for someone else. That's really important in the black community, especially in STEM and for girls," she said. Chase's commitment to seeing things through shows in her soccer career. She was named all-conference as a freshman, but then sprained a ligament in her knee her sophomore year and suffered other knee injuries her junior year. Because of her UAMS internship, she couldn't have surgery to repair the knee over the summer, so she had to miss playing her senior year. But she's still the manager. "I didn't want to abandon the team," she explained.
ETHAN STRAUSS Age: 17 Hometown: Little Rock High School: Episcopal Collegiate School Parents: Noel and Joan Strauss College plans: Dartmouth College
Last summer, Ethan Strauss got a rare opportunity for a high school student. He interned at Forest Hill Capital, a small Little Rock investment firm, and he didn't spend his time there getting coffee and filing documents. Tasked with modeling the financial growth of a construction materials company to determine its investment potential, Ethan "read through five years of the company's quarterly reports and synthesized its income and cash flow statements and balance sheets," he wrote in his All-Stars essay, and then "linked the spreadsheets and used linear regressions to approximate future share prices." He may continue down that path by majoring in economics at Dartmouth College in Hanover, N.H., but he's also considering international relations. He's been interested in geography since he was a child. He loves learning about different cultures. He's drawn to "the complexity of it all and being able to understand how other people think." He's particularly fascinated by unrecognized countries, areas that are self-proclaimed independent nations "and how it would be to live" in one. Pursuing a career in infrastructure investment could be a way for him to combine investments and international relations. He's sure to maintain a healthy dose of pursuits outside of his studies and work: A tennis ace, he's been half of a doubles team that's won the 3A state championship for four years in a row. He's also passionate about pingpong. His Episcopal counselor, Tricia Morgan, said he blushes when school staffers tell him pingpong "could be his Olympic sport." He's also working to share the sport with others. With the profits from a business he started reselling hard-to-find sneakers, he founded Paddle Together, a program that provides pingpong tables to homeless shelters and community centers.
SHAKIAH WILLIAMS Age: 17 Hometown: Blytheville High school: Blytheville High School Parents: Sharon Harris and Africa Wells College plans: Vanderbilt University
Mississippi County's entire population is less than that of the city of Conway. Shakiah (pronounced "Sha-kai-ah") Williams was born and raised there, in Blytheville. Some would say it's a sleepy town. Williams' high school years, however, have been quite the opposite. After school, she'd report to one of her two major extracurricular commitments: practice for the Blytheville High School cheerleading squad, or to practice and conditioning sessions as part of her membership on the Blytheville Chickasaw GymChicks gymnastics team. Add to that her membership in the school's French Club, FBLA, student council and Student Ambassadors; her time volunteering for the local chapters of both the Special Olympics and National Cancer Society; and her work with the annual Blytheville Christmas celebration "Lights of the Delta." "Honestly, this year it became stressful because of all the work I've had to get done, alongside the sports," Williams said. Part of that work, of course, was preparing to leave the high school nest. "College has always been a stressful subject for me," she wrote in her Academic All-Stars essay. "At one point in time I didn't even have the confidence to apply. I just didn't think I would make it." Her transcript shows how unfounded her fears were: Williams has a 4.22 grade point average. Her ACT score is a composite 30. Her language teacher, Lena Pierce, took her to Nashville to visit her dream school, Vanderbilt University. Williams was subsequently accepted, with just "a few thousand [dollars] a year to get covered," she wrote. "This achievement has helped me take some of the stress off of my mom. She is a single parent and having college paid for is just another weight off of her shoulders."
MICHELLE XU Age: 16 Hometown: College Station, Texas High School: Little Rock Central High School Parents: Joshua Xu and Alice Li College plans: University of Pennsylvania
When Michelle Xu found out she'd been accepted into the University of Pennsylvania, she said it was the happiest day of her life. Last summer she attended the university's Leadership in the Business World program, an intensive four-week curriculum of Wharton School of Business classes, during which Michelle's team created a startup business plan and presented it to their classmates. Michelle said she's "liked being a leader" since she was a child, and the LBW program helped her "[connect] the dots on how as a leader you lead by putting aside your ego." She said she aspires to be a "good leader in the business world," She's the first high school member of the Arkansas Association of Asian Businesses. She's also captain of Central High School's varsity Quiz Bowl team; president of its Future Business Leaders of America chapter, president of the Beta Club; vice president of Mu Alpha Theta, the school's math club; and president and founder of the school's Economics and Finance Club. Michelle said she founded the new club so students could learn about economics, rather than the "pure business" focus of the FBLA club. As valedictorian of her class, Michelle said she uses "a lot of time management" to balance her academic workload with her extracurriculars, and has had to make some sacrifices — she danced competitively until her sophomore year and played piano until her junior year, but quit both in order to focus on her classes and leadership roles. Michelle visits her family in China every three or four years, and she said a recent trip to her parents' hometowns helped her realize that "if my parents worked this hard to get to America, I need to work this hard to show them that I will continue their work."
RAMY YOUSEF Age: 17 Hometown: Little Rock High School: Little Rock Central High School Parents: Ziad Yousef and Muntaha Yousef College plans: Hendrix College or the University of Arkansas at Fayetteville
One glance at Ramy Yousef's transcript makes it clear that he has good study skills. He's ranked seventh in his class of 550 at Central High School, with a GPA of 4.43 in classes as diverse as art, debate and pretty much every AP class ever taught. But it's a question about attending Arkansas Governor's School last summer that really gets him talking about what he loves about education. "You get to learn in an environment where you don't get grades," he said. "Making friends and just waking up and going to learn every day — it was a fun experience." Ramy's motivation to do well in high school has been, he said, simply to get into a good college and pay as little as possible for it. He's got a loftier goal for when he gets there, though: to study chemistry and eventually put that knowledge to work developing new vaccines. Science is a family pursuit. Ramy's dad is an entrepreneur, but his mother is a scientist, one sibling is in medical school and the other is in college studying biomedical engineering. Ramy does science even in his downtime, watching astronomy videos on YouTube. That interest took him to a first-place finish in astronomy at the 2017 Arkansas Science Olympiad. What's so cool about astronomy? "Just the possibility that life can exist on another planet," he said.
Source: https://www.arktimes.com/arkansas/2019-arkansas-times-academic-all-star-team/Content?oid=28988347
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Local Research Center Launches Study of Black People’s Brains
Expanding a collection of African-American brains is hoped to give the AANRI expanded knowledge in the treatment of Black Americans and mitigate risks.
By J. K. Schmid
The Lieber Institute for Brain Development announced the creation of the first African-American Neuroscience Research Initiative (AANRI) Monday.
The Lieber Institute, a Baltimore nonprofit research center, boasts the largest repository of human brains in the world.
Lieber also possesses the largest inventory of African-American brains in the world.
The brains are used in research that explores the link between mind and body looking at physical characteristics of post-mortem brains to discover treatments for psychiatric and psychological ailments including post-traumatic stress and schizophrenia.
“Research shows that African Americans are 20 percent more likely to experience serious mental health problems than the general population, and twice as likely to develop Alzheimer’s Disease,” a March press release said. “Suicide rates for African-American children under the age of 13 are twice as high as children of European ancestry. African-American infant death rates and premature birth rates also are twice that of European ancestry Americans.”
Expanding a collection of African-American brains is hoped to give the AANRI expanded knowledge in the treatment of Black Americans and mitigate risks.
“Research has long been hampered by a lack of diversity in basic science and in clinical trials, particularly in the field of neuroscience,” the release reads. “For example, 81 percent of large-scale genomic datasets are of European descent, even though this group makes up less than 16 percent of the world population.”
The social construct of race has long been critiqued in the medical community. Race may not matter, but “ancestry matters,” representatives of Lieber say.
While genomics (the study of a complete set of DNA) research continues the history of humanity in the African continent, AANI focuses it work on the diaspora in the United States and throughout the Americas.
The limited, that is, White, sampling of genomes (“full” patterns of DNA) exposes Black Americans to risks of suboptimal to dangerous drug interactions and other complications in the treatment of mental illness.
Soliciting tissue from Black Americans is a fraught topic in the aftermath of the monstrous experiments in Tuskegee and violations of basic bodily autonomy and consent in the case of Henrietta Lacks. Lieber and AANI are taking careful conciliatory steps to make sure Baltimore’s Black community is invited into something that will be by and for Blacks.
“My clergy colleagues and I have been studying the emerging science behind precision medicine and believe that this technology has potential for finding cures and treatments for diseases that uniquely affect African Americans,” Rev. Dr. Alvin C. Hathaway, Sr., principal of the African-American Clergy Medical Research Initiative, said in a statement. “This revolution in medicine has largely left behind ethnic minority groups like African Americans, and it is time to change this.”
This article originally appeared in The Afro.
Source: https://www.blackpressusa.com/local-research-center-launches-study-of-black-peoples-brains/
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What Do We Lose If We Lose Wild Axolotls?
On a crisp November morning a little after dawn, grey mist unspools from the surface of the water of a maze of canals and island farms called Xochimilco. I’m just a dozen miles south of the center of Mexico City, a sprawling mega-metropolis, but right now, that’s easy to forget.
Herons line the trees along the banks of the canals. Mountains fade in at the horizon. This early, it’s cold enough that Alejandra Ramos and I are shivering as our boat hums through waterways. When we arrive at Antonio Mendez-Rosas’s farm, the vegetables still look like they’ve been dipped in sugar crystals.
Frost glazes Antonio Mendez-Rosas’s vegetables early one morning.
These canals are the very last wild habitat left for what we’d like to find—a strange salamander called the axolotl, which Ramos, as part of a team from Mexico’s National Autonomous University, is working desperately to save from extinction.
The axolotl is famous and beloved, a celebrity among amphibians. Named after an Aztec god and the inspiration for a Pokemon, it can heal itself better than Wolverine from the X-Men, even regrowing lost limbs. The people of Mexico City recently chose it as their official emoji.
Axolotls, once common throughout Xochimilco, are now rare in the wild.
But there aren’t any here today. Mendez-Rosas, the farmer, says that fishermen used to cast a net and catch 40 at a time. Now, standing by the side of a canal and beckoning us closer, he points to the last place he saw an axolotl wriggling in the mud…more than a year ago. Their population density in these wetlands has nosedived from an estimated 2,340 salamanders per square mile in 1998 to less than 14 per square mile in 2014, the year of the last census. No one knows how many are left now.
On its surface, the axolotl’s plight is the same one faced by countless endangered species around the globe. In Xochimilco, as in many other places, humans have pressed heavily against an ecosystem, imperiling plucky, charismatic creatures. Here, our slimy protagonist is beset on all sides. First, its wetlands have shrunk as Mexico City’s population exploded from about 3 million in the 1950s to some 21 million today. Second, some farmers have introduced invasive carp and tilapia, which gobble up axolotl eggs and compete with adults for food. And third, pollution and sewage have reduced the water quality.
Mist rises off the canals of Xochimilco.
But like all good stories, the quest to save the axolotl is more than it seems. Set in crowded Mexico City, it is a microcosm of conservation in the 21st century. It isn’t a binary choice between pristine wilderness and human despoilment—Xochimilco has been home to island farms like Mendez-Rosas’s for over a thousand years, with axolotls thriving alongside people. And unlike many fragile species, the axolotl won’t go extinct if it’s extirpated from Xochimilco. For well over a century, the salamanders have been raised in laboratories and kept as pets across the globe. They’ll continue to exist as curios and sources of biomedical inspiration.
The future of this salamander will be determined not by which plot of land we chose to preserve, but by how we answer a deeper question: What do we lose if Xochimilco loses its axolotls?
A Colonial Conquest
I first caught the axolotl bug this past summer, when a friend went on a few dates with a grad student who kept some in a genetics lab. Once I started looking, they turned up everywhere. I saw them preserved in jars in the herpetology collection at Harvard University and others alive in a developmental biology lab upstairs. I even met a pet axolotl owned by a toxicologist in Japan.
There’s a good chance that each of these animals can trace their ancestry to just one event, the start of the global axolotl diaspora. In the summer of 1863, while the Union and the Confederacy were busy slugging it out at Vicksburg, France invaded Mexico City to collect on unpaid debts. Hot on their heels, naturalists and biologists followed, as often happened with Enlightenment imperialists.
At the beginning of that century, Napoleon’s troops had dragged the Rosetta stone and other ancient wonders out of Egypt. In conquered Mexico, the French went searching for archeological discoveries to match the Rosetta stone. Perhaps they could find another mystical object with the power to unlock vast recesses of time, to illuminate hidden relationships. They did—only it was biological, not archeological. In 1864, 34 live axolotls were shipped to Paris, and six of those were given to biologist Auguste Duméril. He bred them and shared their progeny with international colleagues. Lab axolotls have been going strong ever since.
A closeup of wildtype axolotls.
Almost immediately, Duméril’s axolotls earned their keep. Axolotls never metamorphose, a curiosity among amphibians and something Duméril likely knew at the time. Instead of losing their gills and crawling onto land like other salamanders, axolotls happily spend their entire lives underwater. They even breed in that form. But in 1865, something even weirder happened. Some of Duméril’s second generation of axolotls spontaneously transformed into air-breathing adults.
It’s possible the Aztecs already knew that axolotls could do this. The concordance is just too perfect: their namesake god Xolotl, twin brother of Quetzalcoatl, had the power to shapeshift. Either way, this hidden extra rung in axolotl development helped early 20th century scientists discover thyroid hormones, which can reliably induce the change.
Today, it seems fair to ask whether the descendants of Duméril’s six salamanders, having lived past the sesquicentennial of their captivity, are even true axolotls anymore.
Digging in, I found a 2015 paper titled, charmingly, “A Tale of Two Axolotls.” One of the paper’s authors, Randall Voss, runs the Ambystoma Genetic Stock Center, a repository of lab axolotls hosted at University of Kentucky and funded in part by the National Institutes of Health. The Kentucky salamanders are different from wild ones in some key respects, he told me on the phone.
Unlike many other salamander species, axolotls keep their external gills into adulthood.
For one, this population is nicer. “It was clearly selected to like human beings,” Voss says. “If you walk into our facility, they’ll just instantly make eye contact, come to the edge of the tank, and start begging for food.” They grow and breed fast, too. But compared with Xochimilco’s axolotls, they are all genetic hybrids. Over time, for reasons that are not totally clear, the lab population of axolotls has been crossbred with other tiger salamanders, the larger taxonomic group to which axolotls belong. That has left many lab specimens with a host of foreign genes, including those that code for a milky white skin, unlike the darker shades of wild axolotls.
Even the wild axolotl had long been an urban animal, says Luis Zambrano, a biologist at the National Autonomous University in Mexico City and another of the “Two Axolotls” authors. It thrived alongside the Aztecs for centuries. But the axolotl wasn’t appreciated in modern, developed Mexico until the last few years, he says, well after development had put it in the crosshairs.
In 2002, the federal government tasked Zambrano with a simple mission: form a scientific opinion about the state of this species. But first he had to catch some. He set out traps full of minnows, stretched out gill nets—nothing. “It was a nightmare,” he says. “I said I would finish this work and never come back to Xochimilco.” Finally, he went to a local festival and met fishermen who knew how to catch axolotls the old way, with cast nets. If you want to get axolotls, they said, hire us. So he did, eventually finding a long-term fishing partner for his research.
Zambrano did return to Xochimilco, again and again, and in the intervening years, he has witnessed its axolotl population dwindle. Faced with a bleak state of affairs, his team has two plans to save the wild salamander. Plan A, the optimistic one, is to protect some of Xochimilco by preserving old-school, axolotl-friendly farming practices. Plan B is to establish another axolotl habitat—an off-world colony, if you will—in the hopes that Xochimilico will be restored…or as a failsafe if it isn’t.
A Future Like the Past
Even as the species hangs in the balance in Mexico City, the axolotl is still a star on the rise in the research world. After all, this salamander could well spark a revolution in medicine, giving us the power to regenerate tissue, heal any body part, maybe even regrow an entire arm or leg.
In the beginning of February, an international team took a major step toward tapping into that power, with the announcement in the scientific journal Nature that the full axolotl genome has been mapped for the first time. With 32 billon base pairs, it’s the longest genome previously sequenced, ten times longer than ours.
To understand how axolotls might someday transform medicine, I meet Jessica Whited in the lobby of a patient building on the bustling campus of Brigham and Women’s Hospital in Boston. Whited, a researcher in the hospital’s department of orthopedic surgery, whisks me upstairs in a whirlwind of energy. In her office, she pulls an undergraduate biology textbook off the shelf and flips to the index in the back.
“Regeneration,” she says, scanning. “In this entire textbook, there is one page. 768. This is why I wanted to work on it.” There’s another reason, too. Her grandfather had a peripheral artery disease, in which plaque chokes off blood flow in a person’s extremities. Half of amputations come from such diseases these days, Whited says, and the other half from trauma. Her grandfather required a series of amputations: a few toes at first, and then his leg below the knee. He died at 62.
Recently, Whited’s team has investigated what exactly happens when a salamander regrows an amputated limb. After about the fifth amputation, even axolotl tissue eventually gives up and responds like a human amputee. That lets her compare axolotl stumps that can regenerate against those that can’t.
Axolotls are kept in many labs to study their special regenerative abilities.
When these stumps didn’t sprout new limbs, it seemed to be because regeneration was blocked, not because it wasn’t sufficiently encouraged. Whited found that the genes in inactive stumps were expressing in overdrive, as if those genes were actively stopping the process. (Until this point, scientists had mostly looked for the opposite—genes that are silent in stumps but turn on when a limb needs to regrow.)
And at least one of these genes that stops axolotl tissue from regenerating is closely related to a gene in mammals that causes scarring. Regrowing a limb, it seems, could be an ancestral response that our own bodies just suppress.
Another bit of dogma has been that the magic of regeneration happens right at the stump. But that’s not true in axolotls, Whited discovered. When they lose a limb, cells in the heart, spinal chord, liver, and perhaps all over the body are called into action and start dividing. This happens in mice, too—if you injure a mouse’s leg, muscle stem cells in the other leg start dividing—and it may happen in humans as well.
“It’s possible that we’re not as bad off, from a medical standpoint, as we thought we were,” Whited says. This body-wide response is like the seed of regeneration. Axolotls form a mass of cells that acts as fertile soil for that seed, while mice and humans don’t. But in the future, maybe, we could engineer a more suitable stump, she says.
As we talk, Whited, who has built up a deep love for her subjects over the years, peppers me with question about my reporting on the wild axolotls in Mexico City. I turn her questions around. As a researcher, she has pretty much everything she needs with the lab salamanders, save maybe a little more genetic diversity. So why care about the wild ones?
For once, she’s flummoxed. But just for a second. First, she says, the axolotl is a poster child for all the species with miraculous, useful adaptations that we don’t find before it’s too late. But she’s more philosophical about it, too. “I’m not a conservation biologist, but I’m still a biologist, and I’m still a human being,” she says. “I don’t know what to say to the person who thinks that it’s not worth saving.”
An Insurance Policy
On the phone, Zambrano had invited me to Mexico to see the conservation work myself. A few months later, I take him up on the offer and hop on a plane.
First up is Zambrano’s Plan B, which is hidden in the middle of the city off the side of the highway. The project is in the purview of Alejandra Ramos, a postdoc in his lab. She takes me there on my first evening in Mexico by hailing a cab and directing the driver from the back seat.
When we get out, Ramos knocks on a thick metal slab, and a tiny rectangle at head height slides open like we’re begging entrance at a medieval castle. An elderly security guard lets us in.
This is the Cantera Oriente, an abandoned rock quarry. “Very few people know this place exists,” Ramos tells me as she rummages through her equipment in a small closet tucked behind a women’s bathroom. After mining ceased here, groundwater springs bubbled up from underneath, creating four small lakes in a bowl surrounded by unnaturally steep cliffs. Insects came, and countless birds did, too, transforming one of the city’s deadest places into an artificial, but remarkably alive, oasis. The university now uses it as an ecological research site.
Recently, these lakes have also hosted ten axolotls implanted with radio trackers. For an animal so often studied, our basic ecological understanding of axolotls in the wild is fragmented and incomplete. Ramos is trying to understand how axolotls spend their time. She advertised online for some two dozen volunteers to track the salamanders day and night, mostly attracting biology and veterinary students from the university.
Cantera Oriente, once a quarry, has been mooted as a wild axolotl reserve.
Zambrano’s work has drawn attention to the little critters. Once unloved, axolotls have become the toast of the town. One of the volunteers showed me her own axolotl illustrations. Another shared a smartphone picture of a new axolotl mural in Reforma, an august neighborhood at the heart of the city. And the same government office that ran the official emoji contest just donated a submarine drone to Zambrano’s research effort. “I didn’t even know those existed,” Ramos says.
As the sun sets, Ramos heads home. Volunteers Andres, Esmeralda, and Karen come through the gate. We walk down a path to one of the lakes, push a boat in, and row around as the twilight deepens, brushing off spiders, listening to the beeps from a radio antenna as we try to maneuver the boat on top of each axolotl to record its position.
As they work, the volunteers, delighted to be experiencing nature in the middle of a megacity, try to scare me with a ghost story. They tell me the old security guard claims he sees a man here at night, a figure who stands behind the pine trees, ducks out, and hides again. But the only ghost we find is a faint blip on an unexpected frequency band. In January 2017, the volunteers say, two radio-tagged axolotls were released for an earlier experiment. The female was never caught again. Could this be her?
When I ask Ramos about it later, she is skeptical. The radio transmitters die after only about 50 days. This blip is just signal interference. But the basic fact is true, that not every axolotl in the Cantera Oriente is accounted for. It’s a welcome development, she says. Sooner or later, some will breed here, even though it’s a different ecosystem than the swampy canals they evolved in.
In a previous job, Ramos spent a year on a mountain in Baja California, working with California condors. Those giant raptors have been saved from extinction, but their survival relies on heavy human involvement. She wonders—worries—whether axolotls will reach the same point. A vault of wild-ish axolotls in the Cantera Oriente would be a good insurance policy, a compromise. Better still would be never having to use it.
A Future Like the Past
There’s one more possible future left, the most hopeful one. It harkens to the past, toward the kind of balance established centuries ago by Xochimilco’s pre-Columbian residents. On his sun-drenched plot in Xochimilco, I speak to Mendez-Rosas, the farmer, while Ramos translates. Mendez-Rosas, 42, says the artificial island we’re standing on has been in his family a long time. He has 17th-century documents attesting as much in Nahuatl, the Aztec language, and another paper from 1868, the same year Dumeril started sending axolotls abroad along Europe’s growing railroad network.
Mendez-Rosas’ grandfather and great-grandfather taught him how to farm here, using nutrient-rich muck shoveled out of the waterways instead of fertilizers and pesticides. And through her cooking, his great-grandmother taught him about the axolotl—with its pleasing fishy flavor and cartilaginous crunch, served with local herbs and maize. You eat it head to toe, he says.
The axolotl was a part of the area’s ecological heritage, yes, but it was also food, a part of the culture. Axolotls fed the Aztecs and Cortez’s conquering army alike. In the 1820s, a visiting European naturalist praised their flavor and wrote that you could buy them in nearby markets either alive or roasted.
Now Mendez-Rosas is working with neighboring farmers to build an ecological refuge. Using organic products and old-school farming methods, they aim to support not just themselves but the axolotls and the rest of Xochimilco’s native species. Safeguarding the right habitat will take a fusion of traditional and scientific knowledge, he argues. With a rake, he pulls out a clump of plants to illustrate his own expertise. Here are the little roly-poly crustaceans the axolotl eats, he says. Here’s where they hide. Here’s where they attach their eggs.
That kind of collaboration may be long overdue. For centuries, Western naturalists have monologued about the axolotl. “The colonialism is not just that they brought important animals or plants to Europe,” Zambrano says at the university, it’s also that they didn’t ask Mexican scientists or common people what they already knew. “They despised the local knowledge,” he says. But by joining with Mendez-Rosas, he hopes to turn that around. “If the Aztecs did something for 2,000 years, maybe it’s working.”
Antonio Mendez-Rosas’s farm, soon after dawn.
After chatting with Mendez-Rosas, we take a ride through the canals as the sun continues to climb. By the time we get back to the boat dock, food stands are opening, and a telltale reggaeton beat pulses through a stereo somewhere. Xochimilco, this surviving piece of Mexico City-that-was, is a favorite destination for tourists and locals alike. That attention, and the detritus left by so many visitors, isn’t necessarily great for the axolotl either. By cherishing Xochimilco, modernity is also squeezing it just a little harder.
The ideal goal, Zambrano says, is not to save the last wild axolotls but to protect this entire one-of-a-kind ecosystem. It’s what Mendez-Rosas wants, too. In ten or 20 years, he hopes his land will be bursting with crops and the refuge teeming with animals. “And I want to eat axolotls again,” he says.
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