#DMT TRIP REPORTS

[dialmforolrik]

I remember this one time during a DMT flash there was this weird "dude" (not that he was anthropomorphic of anything, but he definitely gave off these just-some-guy vibes) made of Tchaikovsky's 1812 Overture and the smell of wet dirt but in the form of a small rubber dog toy. He was like "oh booy, look how I can streeeetch!". And then he bended till he had the shape of a cathedral, except the cathedral was built with the taste the color purple would have if you could lick it. Anyway I think about that guy at least once a week. Hope he's having fun wherever he is.

[gerhardfourie]

How To Attain A Permanent State Of Beautiful DMT Consciousness — As Answered By A DMT Entity 

[mbvvacationbibleschool]

Vaping N-N-DMT - Toes in the Water

So I had procured a DMT vape pen from the internet over a year ago and it sat in a drawer as a novelty object for the vast majority of that time. I did try it twice before this at miniscule dosages- probably around 5 mg (a couple seconds long drag) to try to get a feel for it. This time I wanted to try to actually get a feel for it and so when I was loosened up by 2.1 grams of phenibut and some edible cannabis I busted it out again - this time on a deck at night in a town with a very dark late summer sky.

I was with my trusted friend TOBIAS for moral support and I laid back and took a 5 second draw and held it in. After about 15 seconds, the sky started to shift and my heart started to race.

Initially, it looked like the stars were organizing into symettrical patterns that I saw as resembling molecules. Then, it appeared that there was a massive disk shaped craft in the sky, navy blue and taking up most of the space above, with blinking LED lights on the underside in a mandlebrot-like pattern. . . Then I came down.

After a few minutes, I tried again with a few second drag. As it started coming on this time, I hit it again for a couple seconds. This time, I felt my entire body tingling and warm, this felt a lot like the body high of a 4-substituted tryptamine (like psilocybin mushrooms), and I decided to close my eyes. I saw these two objects moving in tandem, shifting about like the coupling rod on a train's wheel, but where that bolt would be, was a squarish inflorescence of brightly colored geometry. There was more to it, but I can't remember any more.

I found the headspace extremely clear compared to the visual effect. It does have this attention mediating aspect though - in that it removes you from the moment before taking it. . . kind of like the feeling of making eye contact with a wild animal in the distance. Otherwise, the cognitive effects are subtle compared to the sensory.

The next day I wanted to try it again because YOLO. I had smoked more cannabis and was around the point of stoned - modified sense of body, light visual disconnection, warm glow, sedation, etc. This time I was lying on a couch in the corner of the deck by a table near the door. There was a ceiling fan above. I took the first drag and waited a moment, but there was suddenly someone rummaging about in the kitchen around the corner. I hesitated, but I persisted anyways, and took another several second drag this time (possibly, the highest total dosage yet).

My hands became these machines or antennae and there was this black beam that was flashing between them to connect them together. I hurredly closed my eyes. My body lit up like a hot metal rod, glowing reddish pink behind my eyelids, with a strong BUZZING sensation that encompassed my entire body. I was struck with an instant powerful feeling of an impersonal anger of some sort? I felt severe discomfort and a bit of anxiety but I was clear headed enough to feel it as a physiological reaction to the drug - and this understanding that the feeling of worrying about someone coming out to the porch had polluted my vibe. This feeling was intense and the primary focus of the 2 minute trip. "It is capable of getting very angry," I said aloud. This didn't really leave me shook or anything - it served as a warning, mostly - like a bee that reminds you that it will sting if provoked.

It is interesting that the body load doesn't happen every time, or maybe it appears almost instantly at a certain threshold of dosage, and it felt the same in a tactile sense both times I felt it, but this second night it presented the same sensation as very dysphoric. Take this one with care- it was easy to see it as casual despite the warnings online because a vape is so easy to titrate low doses, and a couple of times I was treated to some relaxing eye candy. So now I've seen two sides of DMT at low dosages (albeit on top of other substances) and perhaps I will see what it offers in a higher dosage some day.

[cookie-waffle]

“biblically accurate” trippy ass dmt entity-lookin’ Hylia headcanons:

- Mortals cannot comprehend her true physical form, so, she looks different to everyone depending on the individual observing her.

- She does feel genuine love for Link, but it’s a kind of love that is indescribable for mortals. It’s isn’t exactly romantic or queerplatonic love, but, no language has the words to really describe it.

- Despite mortals often depicting her as entirely female, she doesn’t really have a binary gender. She gives off a “feminine vibe” to most who encounter her, but, she’s also known to appear much more androgynous or even masculine to some people.

- She is almost universally considered a benevolent entity, however, her mere presence can also strike terror in those who frequently harm the innocent, and it can cause long term psychological effects in mortals.

-She doesn’t read minds, but she can speak to people telepathically.

- Mortals who take stuff like, “special hylian shrooms” might meet Hylia and actually get to see her true form, but will have trouble recalling what she looks like after the trip ends.

- Hylia is never reported to have two eyes. She almost always appears with three or more, or one big eye. wonder where the weak point is

-She also never only has two wings. She’s been seen with 2 pairs to hundreds of pairs. And they’re the same color as the goddess plumes from Skyward Sword.

- Link is one of the few mortals that can be around Hylia for long periods of time without feeling too overwhelmed by her presence.

- Link was never pressured into serving by Hylia’s side. Although, his decision was heavily influenced be the intense feelings of love and protection he gets whenever he’s around her.

- Hylia is not a selfish goddess, and is actually much more empathetic towards mortals than most. However, she has accidentally killed them in the past due to her not fully understanding the limits of their bodies.

- Hylia and the Goddess of Time from Majora’s Mask are alternate versions of each other.

- Hylia has the power to ascend mortals to godhood, but chooses not to because the power can easily take over them. This is exactly what happened to the Fierce Diety.

[us-the-voices-and-more-voices-2]

tbh the whole autistics have more DMT in them than most people explains so much

In conclusion, a wide range of recent studies provide new support for the hypothesis that pineal gland dysfunction and abnormal metabolism of its related products might be a significant, still unrevealed cause of ASD. Elevated levels of the endogenous psychotomimetic molecule bufotenine has been reported in urine of ASD patients (88), but as far as we know, no assessment of DMT in ASD patients has been performed. We hope that this perspective will encourage future research to test the hypothesis that DMT metabolism is associated with ASD development, and reexamination of the results attributed to vitamin D dysfunction; only this time, based on the pineal gland/melatonin malfunction premise. The results of such studies have the potential to lead to an effective and relatively simple treatment and maybe prevention procedure for ASD, using exogenous melatonin (97, 98) even for infants (99). In addition, treatment could include monitoring of light exposure in infants, toddlers, pregnant women, breastfeeding mothers, and providing pumped breastmilk to the infants according to the time it was expressed (day or night) in order to assure the proper levels of melatonin. -national library of medicine

so interesting, and also makes so much sense to me.

(I have always said "I always feel like I'm tripping, like if I look at a wall its crazy")

but like so interesting!

please add more if you want, feel free to fact check as well <3

[planetarybound]

Thorbahn is one of the first in a class of so-called “psychonauts” exploring new frontiers in hallucinogenic research, preparing to use a technology called extended-state DMT. When the drug is smoked, a trip lasts minutes—despite feeling much longer. But with a constant stream of DMT supplied to a user and blood serum levels of the molecule regulated, that trip can last hours or even days—seemingly an eternity.

The method might give Thorbahn and other psychonauts enough time to bring back detailed trip reports of their experience. An intriguing aspect of DMT experiences is a degree of similarity. The landscapes and beings can be recognizable to different users (a mechanical elf is a popular recurring visitor). And for Thorbahn, the trips seem “more real than real,” a quote heard often in DMT-experimenting circles. Advocates of extended-state programs want to know whether these experiences illuminate a new corner of the mind, even another dimension—or whether users are just getting really high.

Thorbahn, who has a background in biology and chemistry and runs an organic soil company in Colorado, was driving a highway late one night while listening to a psychedelics podcast when he first heard about the extended-state DMT program, DMTx, offered by Medicinal Mindfulness. The latter organization, founded in 2012 in Boulder, Colorado, by two psychotherapists, is a psychedelic therapy clinic and provides cannabis and ketamine-assisted sessions, claiming to have helped treat trauma, depression, and “feelings of meaninglessness.” Its website emphasizes that the clinic “fully complies with all local and Colorado State cannabis laws, and all federal regulations.” DMTx is a new offshoot, founded in 2016 with a long-term goal to “develop and implement FDA-approved clinical research” into DMT, according to its website. In the meantime, the website reads, “While we’ll continue to follow stringent safety protocols, working outside some of the cultural constraints of the FDA allows us to explore a model that is congruent with the passionate interests of the psychedelic community. Namely, to explore the important question: What in the world is really going on here?”

[feleshero]

◇

Why Aren’t We Roleplaying? Well, according to @redhead-reporter ◇ - Other/idk just wanted to say hi

Y'know? This actually reminds me of a parable my great grandmother Veronique Reillance Magdalene (No relation) used to tell me in my most feverish of DMT Trips. Would you like to know what she said to me, Shaye?

She used to say to me: Hey. Listen... Sometimes? It bes like that. And you gotta let it bes like that. But when its no longer like that? You'll feel it, and you won't even be able to remember a time that it wasn't like that. Now roll over onto your side, baby, you shouldn't be on your back right now in case you start coughing.

[the-empress-7]

Psilocybin is a naturally occurring psychedelic prodrug compound produced by more than 200 species of fungi.

The most potent are members of the genus Psilocybe, such as P. azurescens, P. semilanceata, and P. cyanescens, but psilocybin has also been isolated from about a dozen other genera.

Psilocybin is itself biologically inactive but is quickly converted by the body to psilocin, which has mind-altering effects similar, in some aspects, to those of LSD, mescaline, and DMT.

In general, the effects include euphoria, visual and mental hallucinations, changes in perception, a distorted sense of time, and perceived spiritual experiences. It can also cause adverse reactions such as nausea and panic attacks.

In Mesoamerica, the mushrooms had long been consumed in spiritual and divinatory ceremonies before Spanish chroniclers first documented their use in the sixteenth century. In 1959, the Swiss chemist Albert Hofmann isolated the active principle psilocybin from the mushroom Psilocybe mexicana.

Hofmann's employer Sandoz marketed and sold pure psilocybin to physicians and clinicians worldwide for use in psychedelic psychotherapy. Although the increasingly restrictive drug laws of the late 1960s curbed scientific research into the effects of psilocybin and other hallucinogens, its popularity as an entheogen (spirituality-enhancing agent) grew in the next decade, owing largely to the increased availability of information on how to cultivate psilocybin mushrooms.

The intensity and duration of the effects of psilocybin are variable, depending on species or cultivar of mushrooms, dosage, individual physiology, and set and setting, as was shown in experiments led by Timothy Leary at Harvard University in the early 1960s. Once ingested, psilocybin is rapidly metabolized to psilocin, which then acts on serotonin receptors in the brain. The mind-altering effects of psilocybin typically last from two to six hours, although to individuals under the influence of psilocybin, the effects may seem to last much longer, since the drug can distort the perception of time. Possession of psilocybin-containing mushrooms has been outlawed in most countries, and it has been classified as a scheduled drug by many national drug laws.

Leary and colleagues proposed that psilocybin heightens suggestibility, making an individual more receptive to interpersonal interactions and environmental stimuli. After ingesting psilocybin, a wide range of subjective effects may be experienced: feelings of disorientation, lethargy, giddiness, euphoria, joy, and depression. Volunteers given a high dose reported feelings of significant fear and 17% experienced transient paranoia. A 2011 prospective study by Roland R. Griffiths and colleagues suggests that a single high dosage of psilocybin can cause long-term changes in the personality of its users.

Common responses include pupil dilation (93%); changes in heart rate (100%), including increases (56%), decreases (13%), and variable responses (31%); changes in blood pressure (84%), including hypotension (34%), hypertension (28%), and general instability (22%); changes in stretch reflex (86%), including increases (80%) and decreases (6%); nausea (44%); tremor (25%); and dysmetria (16%) (inability to properly direct or limit motions).

Most of the comparatively few fatal incidents reported in the literature that are associated with psychedelic mushroom usage involve the simultaneous use of other drugs, especially alcohol. Probably the most common cause of hospital admissions resulting from psychedelic mushroom usage involve "bad trips" or panic reactions, in which affected individuals become extremely anxious, confused, agitated, or disoriented. Accidents, self-injury, or suicide attempts can result from serious cases of acute psychotic episodes. Although no studies have linked psilocybin with birth defects, it is recommended that pregnant women avoid its usage.

Panic reactions can occur after consumption of psilocybin-containing mushrooms, especially if the ingestion is accidental or otherwise unexpected. Reactions characterized by violent behavior, suicidal thoughts, schizophrenia-like psychosis, and convulsions have been reported in the literature. A 2005 survey conducted in the United Kingdom found that almost a quarter of those who had used psilocybin mushrooms in the past year had experienced a panic attack. Other adverse effects less frequently reported include paranoia, confusion, prolonged derealization (disconnection from reality), and mania. Psilocybin usage can temporarily induce a state of depersonalization disorder. Usage by those with schizophrenia can induce acute psychotic states requiring hospitalization.

Well, this certainly explains a few things. Paranoia you say?

[arrionefinch034]

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[wholepaperfactory]

What is DMT?

Dimethyltryptamine, commonly known as DMT, is a powerful psychedelic compound that is naturally found in many plants and animals, including humans. It is known for its intense, short-lived hallucinogenic effects. Here’s a comprehensive overview of DMT online: 

Chemical Composition and Origins

Chemical Structure: DMT is a tryptamine molecule, chemically similar to the neurotransmitter serotonin and other psychedelics such as psilocybin (found in magic mushrooms for sale) and LSD.

Natural Occurrence: DMT is found in various plants, such as those used in traditional South American shamanic practices like Ayahuasca. It is also present in trace amounts in the human brain, although its exact function is not well understood.

Mechanism of Action

Serotonin Receptors: DMT primarily acts on the brain's serotonin receptors, particularly the 5-HT2A receptor. This interaction results in its potent psychedelic effects.

Rapid Metabolism: When smoked or injected, DMT is rapidly metabolized by the body, leading to a very short but intense experience. When ingested orally in combination with an MAOI (monoamine oxidase inhibitor), as in Ayahuasca, the effects last longer.

Effects on the User

Buy DMT is renowned for its powerful and often profound effects, which can include:

Intense Visual and Auditory Hallucinations: Users report seeing complex, colorful geometric patterns, otherworldly landscapes, and sometimes beings or entities.

Altered Sense of Time: Time can feel drastically slowed down or sped up.

Ego Dissolution: A feeling of losing one's sense of self, often described as merging with the universe or experiencing a higher level of consciousness.

Emotional and Spiritual Experiences: Many users describe their DMT experiences as deeply spiritual or life-changing, providing insights or feelings of oneness and interconnectedness.

Methods of Use

Smoking/Vaping: DMT is often smoked or vaporized, leading to an intense but short experience lasting about 5 to 30 minutes.

Injection: Rarely, DMT is injected, which also results in a short, intense trip.

Oral Ingestion: In traditional Ayahuasca brews, DMT is combined with an MAOI, extending the experience to several hours.

Risks and Side Effects

While many users report positive and enlightening experiences, DMT also carries potential risks:

Psychological Distress: The intensity of the experience can be overwhelming, leading to anxiety, panic, or confusion.

Physical Effects: Increased heart rate, elevated blood pressure, dizziness, and nausea are common, especially with Ayahuasca.

Flashbacks: Similar to other psychedelics, some users may experience flashbacks or spontaneous recurrences of the trip.

Legal Status

DMT is classified as a Schedule I controlled substance in many countries, including the United States, making it illegal to manufacture, possess, or distribute. However, certain traditional and religious uses, such as Ayahuasca ceremonies, may be legally permitted in some jurisdictions. buy dmt online

Therapeutic Potential and Research

Despite its legal status, there is growing interest in the potential therapeutic uses of DMT:

Mental Health Treatment: Preliminary research suggests that DMT and Ayahuasca may have benefits for treating conditions like depression, anxiety, PTSD, and addiction.

Neuroplasticity: Studies indicate that DMT may promote neuroplasticity, potentially leading to new treatments for neurological disorders.

DMT is a powerful psychedelic with a rich history of traditional use and a growing body of scientific research exploring its therapeutic potential. While it offers profound and potentially transformative experiences, it also carries significant risks and remains illegal in many parts of the world. As research continues, our understanding of DMT’s effects, benefits, and risks will likely expand, potentially leading to new avenues for mental health treatment.

Best Ways to Consume DMT

If someone has made an informed, responsible decision to use DMT and is in a location where it is legal or part of an approved study, here are some common methods of consumption along with their respective considerations:

1. Smoking or Vaporizing

Method: DMT is usually consumed by smoking it in a pipe or vaporizing it in a dedicated vaporizer.

Dosage: Typically, 30-60 milligrams for a strong experience.

Effects: Rapid onset within seconds, with intense effects lasting 5-15 minutes and gradually diminishing over 30-60 minutes.

Pros: Quick onset and short duration, which can be beneficial for those who prefer a shorter experience.

Cons: The intense and fast-acting nature can be overwhelming for some users.

2. Ayahuasca

Method: A traditional South American brew made from DMT-containing plants and an MAOI (monoamine oxidase inhibitor) to allow oral ingestion.

Dosage: Varies significantly depending on the preparation and individual sensitivity.

Effects: Slower onset (30-60 minutes) with a longer duration (4-8 hours).

Pros: The longer duration allows for a more gradual and potentially manageable experience. Often taken in a ceremonial setting with guidance.

Cons: Can cause nausea and vomiting due to the MAOI. Requires careful preparation and knowledge of traditional practices. 

3. Changa

Method: A smokable blend of DMT and other herbs, often containing an MAOI.

Dosage: Similar to smoking pure DMT, usually 30-60 milligrams of DMT within the blend.

Effects: Onset and duration are similar to smoking pure DMT, but the effects can be slightly more extended and smoother due to the presence of the MAOI.

Pros: Easier to handle and dose than pure DMT. The addition of herbs can enhance the experience.

Cons: Requires careful preparation and knowledge of the blend components.

Safety and Considerations

Set and Setting: Ensure a safe, comfortable environment and a positive mental state. Having a sober, trusted sitter present can provide support and safety.

Dosage: Start with a low dose to gauge sensitivity and response.

Legal Status: Be aware of and comply with the legal status of DMT in your location.

Health Conditions: Avoid use if you have a history of mental health issues or are on medications, especially antidepressants or other substances that interact with serotonin.

Preparation: Research and understand the method you choose, including potential side effects and risks.

Medical Benefits of DMT

DMT (Dimethyltryptamine) has garnered increasing interest in the medical and scientific communities for its potential therapeutic benefits. While research is still in the early stages, preliminary studies and anecdotal evidence suggest several potential medical benefits:

1. Treatment-Resistant Depression

Research Findings: Early studies suggest that DMT, particularly when used in the form of Ayahuasca, can significantly reduce symptoms of depression. The effects are often rapid and can last for weeks to months.

Mechanism: DMT's impact on serotonin receptors, especially the 5-HT2A receptor, is believed to play a crucial role in alleviating depressive symptoms. Additionally, DMT may promote neuroplasticity, helping the brain form new neural connections.

2. Anxiety and PTSD

Research Findings: DMT has shown promise in reducing anxiety, including generalized anxiety and anxiety related to post-traumatic stress disorder (PTSD). Some studies indicate that it can help users process traumatic memories and reduce fear responses.

Mechanism: The altered states of consciousness induced by DMT can provide new perspectives on traumatic experiences, potentially leading to emotional healing and reduced anxiety.

3. Substance Abuse and Addiction

Research Findings: Some studies and anecdotal reports suggest that DMT and Ayahuasca may help individuals overcome addiction to substances such as alcohol, nicotine, and opioids.

Mechanism: The profound, often spiritual experiences facilitated by DMT can lead to insights and behavioral changes that support addiction recovery. The increase in neuroplasticity might also help rewire brain circuits involved in addictive behaviors.

4. End-of-Life Anxiety

Research Findings: DMT has been studied for its potential to alleviate anxiety and fear related to terminal illnesses. Patients report reduced anxiety, improved mood, and a more positive outlook on life and death.

Mechanism: The deep, often mystical experiences induced by DMT can help patients come to terms with their mortality, reducing existential anxiety and promoting peace.

5. Neurogenesis and Neuroplasticity

Research Findings: Some research indicates that DMT may promote neurogenesis (the growth of new neurons) and neuroplasticity (the formation of new neural connections).

Mechanism: By enhancing neuroplasticity, DMT may support brain health and cognitive function, potentially aiding in the treatment of various neurological and psychiatric conditions.

6. Psychological Insight and Personal Growth

Research Findings: Users often report significant personal insights, emotional release, and psychological growth after using DMT. These experiences can lead to long-term improvements in mental health and well-being.

Mechanism: The altered states of consciousness and introspective nature of DMT experiences can help individuals process emotions, resolve inner conflicts, and gain a better understanding of themselves and their lives.

Conclusion

While the potential medical benefits of DMT are promising, it is important to note that research is still in its early stages. Most studies have been small-scale and require further validation through larger, controlled trials. Additionally, DMT is a powerful psychedelic with significant risks, especially for individuals with certain mental health conditions or those taking medications that interact with serotonin.

Anyone considering DMT for therapeutic purposes should do so under the guidance of a qualified healthcare professional and within the bounds of the law. As research progresses, we may gain a clearer understanding of how DMT can be safely and effectively integrated into medical practice like psilocybin edibles such as golden ticket mushroom bar for sale

[ez-ra-zed]

Dextromethorphan protects the brain from sleep Deprivation ;) a little bit, not entirely. It's an antioxidant? So are benzodiazepines, which also protect from sleep deprivation, and my favorite class of nootropics Racetams, which also protect from sleep deprivation - the best potentiators for psychedelics which I learned on my own by combining Piracetam and LSD with my friend Zion to pull an all nighter, without reading other peoples trip reports, and confirmed they were potentiators for 5-HT2a agonists when I found tons of others who discovered the same thing - on their own - one reason why I know anecdotal evidence to be valid, as there is no other way to gather data on these experiences besides the Internet, social media, forum sites... The DMT-Nexus taught me about the fifth dimensional hyperspace water wheel, the salvia wheel - Samsara, one of infinite wheels, however most people only see the one because this is the one universe they know, and only multidimensional minds like mine understand that there are infinite wheels and that only some of those wheels are a part of Lady Salvias music collection

Anyways, whenever I do psychedelics I feel a little special Ed, I feel like I can't use words in an eloquent manner however when we mixed Piracetam with LSD we were on the same page and I taught him something fundamental about consciousness, that he may or may not carry with him for the rest of his life

[shroomsshroom]

DMT (Cartridge and Battery) .5mL Deadhead Chemist

N, N-Dimethyltryptamine (DMT) is a tryptamine drug with hallucinogenic properties that naturally occurs in various plant species used in religious practices and rituals. It has earned the nickname "spirit molecule" due to its potent psychedelic effects.

Other names for DMT include "businessman's trip," "businessman's special," "fantasia," and "45-minute psychosis." DMT is the active ingredient in ayahuasca, a traditional South American brewed tea used for its psychoactive and hallucinogenic effects. One of the most commonly reported positive side effects of the drug is "spiritual insight." The primary effect of DMT is psychological, with intense visual and auditory hallucinations, euphoria, and an altered sense of space, body, and time.

This particular product contains 400mg of DMT in a 0.5mL vape cartridge, promising a psychedelic experience that transports the user to the magical and colorful dimension of Dimitry's Magic Stick. Shop now.

[formeroklahoman]

December 30, 1962, and several other occasions, Leary attempts to buy one hundred grams of LSD and twenty-five kilos of Psilocybin.

Bureaucratic Hurdles

With their projects freed from the constraints of the university, the spectrum of psychedelic experiments at Millbrook assumed new dimensions. However, the necessary supply of psilocybin and LSD could no longer be ordered through the university. Nevertheless, on December 30, 1962, Leary ordered one hundred grams of LSD and twenty-five kilos of psilocybin from the English company L. Light & Co., an English co-contractor of Sandoz, on Harvard University letter head. The company’s director, Henry de Laszlo, thanked Leary but asked for more information about the purpose of the unusually large quantities—that much LSD would suffice for a million trips at one hundred micrograms. At the same time, he informed Albert Hofmann with whom he seems to have been acquainted, and both wondered why the order was not sent to Sandoz in Basel or to its America Branch. Leary, too, seems to have been uncertain and on January 11, 1963, probably unaware that it was Hofmann’s birthday, he sent an order to Basel, this time addressed to the pharmaceutical company Hoffmann-La Roche. They in turn forwarded it to Sandoz. Again, Leary ordered one hundred grams of LSD and twenty-five kilos of psilocybin and inquired about the availability and price of N,N-dimethyltryptamine (DMT),N,N-diethyltryptamine (DET), 6-hydroxyDMT, psilocin (4-hydroxy dimethyltryptamine)and bufotenine (5-hydroxy dimethyltriptamine); once again the order was sent on the letterhead of his former employer, with Leary’s note that he was the director of a research project studying the effects of psychedelic drugs; tissue and animal tests and further studies with voluntary subjects were planned.

For this purpose, Leary, Alpert, Metzner, Walter Houston Clark, Huston Smith and others founded the International Federation For Internal Freedom (IFIF) on January 23,1963 in Millbrook as a nonprofit psychedelic, educational and research organization. Independent study groups were planned plus magazine, Psychedelic Review. However, the quantities of psilocybin and LSD they had ordered failed to arrive. Instead, they received Albert Hofmann’s letter of January 24th in which he expressed his interest and how pleased he was with these projects. He told Leary that Sandoz would gladly provide the product but only directly, not through intermediaries. He mentioned the inquiry to Light & Co. and asked Leary to turn to him personally in the future. That Same day, Sandoz quoted IFIF an offer with details of price, delivery, packaging, and methods of payment. The price was 75 Swiss Francs per gram for psilocybin and 508 Swiss francs per gram for LSD. IFIF was requested to include the import license from the proper authority with their final order. Sandoz added that “the other substances mentioned in your enquiry can in principle also be supplied by us and we would be very thankful to you if you would let us know by next mail the quantities you intend to order for each product to enable us to prepare a special offer for your university. You may be assured that we shall not fail todo all in our power to satisfy you in every respect and thanking you in anticipation of your further news.” Five days later, YvesDunant, the general manager of Sandoz circulated an internal memo: “Mr. Masonwarns against sending Dr. Leary the 25 kilos of psilocybin and 500 grams of LSD he ordered. We will receive a letter from Dr.Henze next week with the necessary explanations.” Two days later, a telegram arrived at Sandoz from L.G. Wiggins, vice president of Harvard University in which he stated that Harvard was not responsible for Alpert’s and Leary’s order of psilocybin and LSD.

On February 7th, the promised letter from Dr. Carlo Henze, manager of the U.S. branch of Sandoz, reached Yves Dunant in Basel. Among other things, he reported: “That there is ample evidence that LSD has been smuggled into this country from various outside sources, including Mexico, Israel, and perhaps Italy and that the federal authorities have looked upon this with increasing suspicion.... The reason for this interest, aside from the bad publicity, is inherent in the fact that certain groups outside the medical field have been playing around with hallucinogenic substances and that the drug has also found its way into the hands of drug addicts and other fringes of psychopathic personality groups.... I am writing to you today to recommend that no shipment of these compounds be made directly from Basel to any person in this country.” He confirmed that Harvard University was not informed of the order; he concluded that while Dr. Timothy Learywas still a member of the university and was making use of Harvard University stationary, that he knew that Leary had been fired because of the irresponsible manner in which he and his associates had used hallucinogenic substances. In a separate letter to Renz and Hofmann, Henze requested that they refrain at all costs from doing any further business. His information stemmed from, among others, FDA employee HaroldO’Keefe who told Henze that there was abuse, the substances had gotten into the wrong channels and, regarding LSD: “Of All drugs that we know about, we know of none which deserve controlled handling toa greater extent than these.”

On February 13th, Leary again turned to Hofmann, repeated his order, and mentioned that journalists were interested in their projects for an article in LIFE. A down payment in the form of a check for over ten thousand dollars was enclosed. Meanwhile, Leary’s inconsistencies with regard to Harvard and the future direction of his projects had turned Hofmann’s initial interest and delight into growing annoyance. His irritation shows in his handwritten note at the reference to media attention in the letter: “That apparently is the most important thing.” Leary continued: “We feel that we are engaged in furthering the important and exciting work that you began. Life gets complicated at times when some of our colleagues fail to grasp its significance. Life must be equally complicated for you.” Again Hofmann Noted by hand: “Certainly after this letter! ”The tone of Hofmann’s response is business-like but notably less friendly than in earlier letters: “Needless to say, our company will proceed in this matter strictly according to FDA regulations.” And, “I note with some concern from your communication that you have given your research project a publicity(e.g. invitation to LIFE reporters) which can only be injurious to the scientific clarification of questions connected with the use of these substances.” For its part, Sandoz sent Leary's Check back to him and turned down the order for lack of an import license.

Leary and his fellow campaigners at IFIF still did not give up, as can be seen from Hofmann’s internal communication of February 28th regarding a phone call from Richard Alpert: “Without prior notice I Received a call from Dr. R. Alpert, a colleague of Dr. Leary, Harvard University, Cambridge, USA. He asked whether the order for one kilogram of psilocybin and one hundred grams of LSD had arrived and what our response was. I filled him in regarding the contents of our written response to Dr. Leary that should arrive shortly. Richard Alpert again explained the basis and goal of IMF's approach. Since Sandoz USA apparently was not willing to take over distribution of LSD and psilocybin or responsibility for their use with respect to the FDA, IFIF had constituted itself as the central contact for a large number of research groups to relieve Sandoz of this task and enable the projects to continue their research with these substances. Based on past negotiations with the FDA, he believed that recognition of IFIF as a sponsor was forthcoming. As soon as they received the required approval from the health authority, IFIF would enter into contract with other pharmaceutical companies for delivery if Sandoz chose not to supply the substances.”

Leary made one more attempt; his letter of March 6th which spoke euphorically of IFIF landed on Hofmann’s desk. A check accompanied the same order as received previously, this time for five thousand dollars, which Sandoz returned on March 19th. Hofmann became unsettled and made inquiries with several friends about Leary and their assessment of his character and the activities of IFIF. Among these contacts was a letter to Aldous Huxley on March 11th in which he summarized events up until then and asked him for information: “Some weeks ago our firm received an inquiry signed by Dr. Leary Of the Harvard University for the delivery of500 gr LSD and 25 kg Psilocybin to be used for the research project of the IFIF. Unfortunately, the LSD, in connection with the Thalidomide-Affair and to some cases of misuse with Psilocybin and LSD, and to which greatest and widest publicity was given for the sole purpose of sensation, was classified as a very dangerous drug. Theseevents caused our branch company in U.S.A.to stop delivery of those substances. It looked as if the IFIF could and would take the respon-sibility for the distribution and application of Psilocybin and LSD towards the FDA. In The above-mentioned inquiry Dr. Learyinformed us that he would procure the nec-essary licenses from the FDA. With the reser-vation that the ‘Clearance’ by the FDA had to be settled, we sent in our quotation. Aftera short time, we received a greater order forLSD and Psilocybin and a check is enclosed for an advanced payment, but the Clearance’ was missing. Furthermore, we got a very unfavorable impression by the fact that in the letter containing the order special attention was called to a visit by LIFE reporters and their great interest in the activities of the IFIF. In doing this the whole project seems to be treated with hasty publicity and undesirable sensation.

These were the reasons why our firm could not accept the order. Delivery is, of course, only possible, if the official licence [sic] from the FDA can be presented.... As you of course know, I am also personally convinced that the psychedelic substances offer, besides their usefulness in psychotherapy, as conscious-ness expanding drugs for educational purposes and for self-knowledge new and not yet fully explored possibilities. Unfortunately, the danger of an uncontrolled or unserious application with undue publicity and sensation is very great and therefore the control of distribution and availability is of greatest importance. In our Western civilization the Tabu [sic]is missing which regulates the use of psychedelic drugs by primitive people. It is difficult to replace Tabu by government regulations and therefore it is of paramount importance to know what kind of persons and organizations are dealing with the application and distribution of psychedelic drugs.”

Huxley answered him on March 21st: “I Have been annoyed and disturbed by the stupid and sensational publicity surrounding LSD and also by the cases of misuse which occasionally occur. Not wishing to add to the publicity, I have refused all invitations, in recent months to write articles about LSD or to speak over the radio. What is needed now is not talk, but solid work on the experimental-psychological and psychotherapeutic levels.

I have known Dr. Leary and his colleague Dr. Alpert for several years and have discussed their projects with them.... In general I am of [the] opinion that Leary and Alpert have done some very valuable pioneering work. They have had enthusiastic collaborators of great ability such as Dr. Huston Cummings Smith, Professor of Comparative Religion at the Massachusetts Institute of Technology, and Dr. Alan Watts, the well known orientalist.``

Huxley’s favorable and supportive endorsement of Leary and Alpert succeeded in quieting Hofmann’s mistrust, but changed nothing in his and Sandoz’ position not to complete an order without approval from the FDA. Since the authorizations never arrived, Leary’s repeated orders remained unfilled.

The refusal from Basel did not stop the psychedelic pioneers in Millbrook from carrying on with their studies and experiments. They were able to procure the necessary substances through other channels. The Researchers gave lectures at universities and scientific conferences and published articles in professional journals. Interested and curious visitors came from around the world for discussions and psychedelic experiences, among them: Writer Robert Anton Wilson, later known as co-author of the Illuminatus!trilogy; London psychiatrist R.D. Laing, cofounder of the anti-psychiatry movement; Paul Krassner, journalist and publisher of the magazine The Realist, Willem A. Nyland,a longtime student of Gurdjieff, and many other friends and acquaintances from their Harvard days.

Mystic Chemist 147-151

#PsychedelicSynchronicity

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Bufo Alvarius. Risks & Negative Effects. Extreme fear and terror can occur. Delayed effects such as muscle tension, difficulty sleeping, and flashbacks to the initial drug session may be experienced up to 1 week after 5-MeO-DMT use. Very few cases report hallucinogen-persisting perception disorder (HPPD) in which psychological symptoms or flashbacks persist weeks to years after psychedelic use. But there hasn't been investigations or organized efforts to collect information about negative outcomes. List of common negative effects: Neusea or vomiting, confusion, delusion, loss of motor control, anger, sadness or anger, tremors, shaking, pupil dilation, blackout, skin flushing etc. Risk of Serotonin Toxicity Drugs that increase the amount of serotonin in synapses can potentially cause serious adverse events if serotonin levels reach a toxic threshold. Medications classified as monamine oxidase inhibitors (MAOIs), serotonin re-uptake inhibitors (SRIs, SSRIs, SNRIs), and serotonin releasing agents (MDMA) are associated with serotonin toxicity. Combination of these drugs can escalate risk for having too much serotonin accumulate in neural synapses. 5-MeO-DMT should NOT be taken with monamine oxidase inhibitors (MAOIs)! As we learned earlier, metabolism of 5-MeO-DMT relies on MAO. If 5-MeO-DMT is taken alone within defined dose ranges, the risk for serotonin toxicity is reportedly low. More research is needed to understand how other sertonergic drugs, including SSRIs, possibly interact with 5-MeO-DMT to affect toxicity. Lithium should be avoided with 5-MeO-DMT because of increased chance of seizures. #psychedelics #bufo #Bufoalvarius #hypnotic #science #hallucinogen #bewusstsein #trip #psychedelicjourney #mystical#5MeODMT #spirituality #meditation #god #consciousness #liberation

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Benefits of Psychedelics: A Comprehensive Guide

Introduction

Psychedelics have been used for centuries for various purposes, including spiritual and therapeutic experiences. More recently, researchers have been exploring the potential therapeutic benefits of psychedelic substances for treating mental health conditions such as depression, anxiety, and PTSD.

How Psychedelic Therapy Can Improve Mental Health

Psychedelic-assisted therapy is a type of therapy that involves the use of psychedelic substances under the guidance of a trained therapist. This therapy has been shown to be effective for treating a range of mental health conditions, particularly treatment-resistant depression and PTSD. It is believed that the experience of a psychedelic trip can help individuals gain a new perspective on their problems and provide a deeper understanding of their thoughts and emotions. Here are my top 5 psychedelics.

Golden Teachers

Golden Teachers are a type of psychedelic mushroom that is known for its ability to induce a powerful psychedelic experience. This mushroom contains psilocybin, a psychoactive compound that has been shown to have potential therapeutic benefits. Some of the reported benefits of Golden Teachers include improved mood, increased creativity, and a greater sense of connection with others.

Penis Envy

Penis Envy is another type of psychedelic mushroom that is known for its potency. This mushroom contains a higher concentration of psilocybin than other types of mushrooms, which can result in a more intense and profound psychedelic experience. Some of the reported benefits of Penis Envy include increased self-awareness, improved creativity, and a greater sense of spiritual connection.

Blue Meanie

Blue Meanie is a type of psychedelic mushroom that is known for its deep blue color and potent psychedelic effects. This mushroom contains psilocybin and has been reported to have a range of benefits, including improved mood, increased creativity, and enhanced introspection.

Malabar

Malabar is a type of ayahuasca, a traditional Amazonian brew that contains DMT, a powerful psychedelic compound. Malabar is known for its ability to induce intense and transformative psychedelic experiences. Some of the reported benefits of Malabar include improved mental health, increased creativity, and a greater sense of spiritual connection.

Jedi Mind Fuck

Jedi Mind Fuck is a hybrid strain of cannabis that is known for its potent psychedelic effects. This strain contains a high concentration of THC, the psychoactive compound in cannabis, and has been reported to have a range of benefits, including increased creativity, improved mood, and a greater sense of connection with others.

Conclusion

While the use of psychedelics for therapeutic purposes is still relatively new, research suggests that these substances may hold promise for treating a range of mental health conditions. However, it is important to note that psychedelics can be powerful substances and should only be used under the guidance of a trained professional. It is also important to be aware of the potential risks associated with psychedelic use, including the possibility of adverse psychological reactions and the potential for addiction.

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