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Clinical Oncology Next Generation Sequencing Market - Forecast(2024 - 2030)
Clinical Oncology Next Generation Sequencing Market Overview
Clinical Oncology Next Generation Sequencing Market size was valued at $1.4 billion in 2020 and projected to grow at a CAGR of 13.6% during the forecast period 2021-2026. Next-generation sequencing is a technique that helps to simultaneously perform multiple reactions from which it is possible to sequence DNA or RNA. Biological sciences have been revolutionized by massively parallel sequencing technologies i.e. next-generation sequencing (NGS). Targeted sequencing and re-sequencing provides advantages such as high throughput and lower cost per sample of the process thereby enhancing its application Companion Diagnostics. It is a method of assessing the nucleotide sequence in a DNA section and is used for oncology research and enables researchers to carry out a wide range of applications and study biological systems with their ultra-high throughput, scalability, and speed at a level never before possible. In addition, sequencing of the next generation helps in the evaluation of several genes in a single assay, thus reducing the need to order numerous tests to evaluate the underlying mutation thereby driving the Clinical Oncology Next Generation Sequencing Market. In tumour science, a high implementation rate in whole-genome sequencing (WGS) has been seen in recent years driving the Clinical Oncology Next Generation Sequencing Market Industry. The emergence of next-generation sequencing clinical applications in precision oncology has accelerated key company’s efforts to create new platforms that can be used for genomic assays. In February 2021, for instance, Congenica partnered with Gabriel Precision Oncology Ltd. to create an automatic software interface for clinical oncology interpretation using biotechnology. In routine clinical practice, this product will promote NGS-based molecular diagnostics of tumours.
Report Coverage
The report: “Clinical Oncology Next Generation Sequencing Market Forecast (2021-2026)”, by Industry ARC, covers an in-depth analysis of the following segments of the Clinical Oncology Next Generation Sequencing Market.
By Technology Type: Whole Genome Sequencing, Whole Exome Sequencing and Targeted Sequencing & Resequencing Centrifuges.
By Application: Screening - Sporadic Cancer and Inherited Cancer, Companion Diagnostics and Other Diagnostics.
By Workflow: NGS Pre-Sequencing, NGS Sequencing and NGS Data Analysis.
By End Use: Hospitals/Clinics, Laboratories and Research Labs.
By Geography: North America (U.S, Canada and Mexico), Europe (Germany, UK, France, Italy, Spain, Russia and Rest of Europe), Asia Pacific (China, Japan India, South Korea, Australia & New Zealand, and Rest of Asia Pacific), South America (Brazil, Argentina and Rest of South America) and RoW (Middle East and Africa).
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Key Takeaways
The increasing need for successful treatment of various cancer types and scientific developments in immunology, molecular biology and genetics are likely to contribute to the growth of the Clinical Oncology Next Generation Sequencing industry.
Geographically, North America Clinical Oncology Next Generation Sequencing Market held the largest revenue share of 36% in 2020 owing to an increased emphasis on cancer treatment by government agencies, a rise in healthcare spending and the presence of sufficient resources in the healthcare industry in this region.
The growth of the market is driven by rising research and development activities using NGS technologies, growing NGS applications in clinical diagnosis and discovery applications that demand NGS technology.
Detailed analysis on the Strength, Weakness and Opportunities of the prominent players operating in the market is provided in the Clinical Oncology Next Generation Sequencing Market.
Clinical Oncology Next Generation Sequencing Market Segment Analysis - By Technology Type
Based on Technology Type, Clinical Oncology Next Generation Sequencing Market is segmented into Whole Genome Sequencing, Whole Exome Sequencing and Targeted Sequencing & Resequencing Centrifuges. Targeted Sequencing & Resequencing Centrifuges accounted for the largest revenue market share in 2020 help reduce the expense, time, and volume of data analysed during tumour sample sequencing which is anticipated to favourably impact the segment growth. Targeted sequencing uses deep sequencing within an area of interest to identify recognized and novel variants. Illumina's 523-gene panel contains all the probable genes that have the ability to cause malignant tumours to develop. Medical laboratories have introduced the product to diagnose patients suffering from acute myeloid leukaemia. In addition, the efficacy of targeted panels for the identification of malignant tumors improves their clinical usefulness. In 64% of cancer cases, NGS panels are clinically beneficial, according to a report reported in JCO Precision Oncology, 2020 driving the Clinical Oncology Next Generation Sequencing Industry. Whole Genome Sequencing segment is anticipated to grow with the fastest CAGR of 8.3% in the forecast period 2021-2026 owing to the usefulness of this technology to discern and compare normal tissues from tumour tissues, segment growth. Moreover, whole-genome sequencing of cancer patients helps to identify therapies for existing mutations and also helps to target mutations ahead of time. It also helps analyse the prognosis of cancer and establish a treatment regimen depending on the genes affected aiding to the Clinical Oncology Next Generation Sequencing Market growth.
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Clinical Oncology Next Generation Sequencing Market Segment Analysis - By Application
Based on Application, Clinical Oncology Next Generation Sequencing Market is segmented into Screening - Sporadic Cancer and Inherited Cancer, Companion Diagnostics and Other Diagnostics. Screening accounted for the largest revenue market share in 2020. The most effective way to identify genetic alterations that can be targeted for clinical benefit in cancer patients is currently considered to be NGS-based testing. This technology enables clinicians to analyse several alterations of genes simultaneously. Moreover, as opposed to other pathology methods, technology needs less tumor tissues. An increase in the number of cancer sequencing projects is also increasing the growth of the segment. For instance, 38 different types of cancer were analysed by the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium by sequencing more than 2,600 tumour samples aiding to the market's growth. Companion Diagnostics segment is anticipated to grow with the fastest CAGR of 9.1% during the forecast period 2021-2026. Efforts taken by key market participants to develop advanced computational tools propel the segment growth. For instance, in January 2021, scientists from the MD Anderson Cancer Center created CopyKAT, a new computational tool to distinguish between normal as well as cancer cells in a tumour thus enhancing the Companion Diagnostics segment demand.
Clinical Oncology Next Generation Sequencing Market Segment Analysis - By Geography
Based on Geography, North America Clinical Oncology Next Generation Sequencing Market accounted for the 36% revenue share in 2020. This rise is accounted for by substantial efforts made by regulatory bodies to boost cancer screening detection in the U.S. For instance, the U.S.-initiated Cancer Genome Atlas programme, Next-generation sequencing has been conducted by the National Cancer Institute (NCI) of more than 20,000 primary cancer samples from 33 different cancer types. A consortium of 12 cancer centres, including Johns Hopkins University, Dana-Farber Cancer Institute, and others throughout the United States, is the NCI's Cancer Aim Discovery and Growth Network enhancing the Clinical Oncology Next Generation Sequencing Market. In January 2020, in the United States, the Intelligence Advanced Research Projects Activity provided $23 million to the Broad Institute and Harvard University, and DNA Script. In addition, the emergence of a range of laboratories, academic institutions and hospitals that provide early cancer detection and treatment services based on NGS is owing to the growth of the regional sector. For instance, EasyDNA Canada, a Toronto-based DNA Biotechnology testing company, provides Cancer Predisposition Panel tests that use NGS technology to recognise mutations in a total of 98 genes associated with 25 inherited cancers. The test helps to recognise people who at a later stage of their lives are at a high risk of developing cancer drive the regional growth. Asia-Pacific is predicted to be the fastest-growing region during the forecast period 2021- 2026 owing to the increasing automation in the pre-sequencing protocols in this particular region thereby aiding to regional growth.
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Clinical Oncology Next Generation Sequencing Market Drivers
Increasing Prevalence of Cancer:
Cancer is the second leading cause of death worldwide, according to the WHO, and was responsible for an estimated 9.6 million fatalities in 2018. Need for cancer therapies is rising with the increasing number of cancer cases and deaths caused by cancer. Thus government of various economies focus on drug development, targeted sequencing for the reduction of cancer cases have also increased. Rising biomedical research using next-generation clinical oncology sequencing is estimated to create a favourable environment in the near future for the growth of the next-generation clinical oncology sequencing industry. With substantial advances in genetic sequencing and biomedical science, much research into monoclonal antibodies is now focused on discovering new development targets and optimizing their effectiveness for clinical practice, demonstrating a significant effect on the need for the Clinical Oncology Next Generation Sequencing Market.
Decreasing Sequencing Costs Are Highly Likely To Lead To Market Growth:
In clinical oncology, research and academic institutions are generally interested in the characteristic features of next-generation targeted sequencing technology. The next-generation sequencing techniques in clinical oncology give a high percentage of reads and cost-effectiveness per read. The arrival of low-cost sequencing platforms on the market has made this possible. This increases the overall growth of the next-generation sequencing market for clinical oncology. Several industry players, such as Roche and Illumina, have launched sequencing techniques that have reduced the cost of next-generation sequencing for clinical oncology. Government support for life science research is also estimated to result in the availability of funding for the undertaking of different next-generation sequencing projects in clinical oncology, as well as for the jobs of the staff needed which further act as a driving factor for the growth of the Clinical Oncology Industry.
Clinical Oncology Next Generation Sequencing Market Challenges
Major Regulatory Concerns & Lack Skilled Professionals:
Regulatory concerns regarding usage of Clinical Oncology Next Generation Sequencing Analysis and growing stringent government policy and regulation towards the quantity of service being used in application is restraining growth of the market. Market restrain is also owing to the difficulty in the management of large data and complications, associated with Big Data management. In addition, some of the ethical issues associated with whole-genome sequencing, coupled with the lack of awareness among people are constraining the growth of the market. In addition, the lack of skilled professionals with the sequencing that could be serious for diagnosis purpose set to restrain the market growth. It gets difficult when in an emergency situation, the queue of patients have to wait for experts in the required field negatively impacting the growth.
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Clinical Oncology Next Generation Sequencing Industry Outlook:
Product launches, mergers and acquisitions, joint ventures and geographical expansions are key strategies adopted by players in the Clinical Oncology Next Generation Sequencing Market. Clinical Oncology Next Generation Sequencing Market top 10 companies are Illumina, Inc., Qiagen N.V., Pacific Biosciences of California, Inc., Takara Bio, Inc., Creative Biolabs, Mogene LC, F. Hoffmann-La Roche Ltd, Oxford Nanopore Technologies, Agilent Technologies and Thermo Fisher Scientific Inc.
Acquisitions/Product Launches:
In January 2021, 4baseCare, a start-up in precision oncology, partnered with the Advanced Centre for Cancer Treatment, Study and Education (ACTREC), India, to develop ClinOme, an AI-driven platform for clinical interpretation
In May 2020, Illumina, Inc., has partnered with Burning Rock Biotech Limited, a cancer test provider based in China, to promote the standardisation and development within China of the selection of NGS-based cancer therapy. The company has also signed an agreement to develop and commercialise myChoice tumour testing in China with Myriad Genetics, Inc.
In March 2019, Oxford Nanopore Technologies launched a new paradigm of smaller, on-demand DNA or RNA sequencing tests with the potential to transform a variety of applications where rapid insights are needed at a low cost.
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The Business Research Company offers clinical oncology next generation sequencing market research report 2023 with industry size, share, segments and market growth
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According to a new report by nova one advisor, the global U.S. clinical oncology next generation sequencing market size surpassed USD 192.27 billion in 2023 and is anticipated to reach around USD 687.04 billion by 2032, expanding at a double digit CAGR of 15.2% from 2023 to 2032
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The U.S. clinical oncology next generation sequencing market size was estimated at USD 166.9 million in 2022 and is expected to surpass around USD 687.04 billion by 2032 and poised to grow at a compound annual growth rate (CAGR) of 15.2% during the forecast period 2023 to 2032.
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U.S. Clinical Oncology Next Generation Sequencing Market Size Is Anticipated To Reach USD 1.53 Billion By 2024: Grand View Research Inc.
San Francisco, 27 April 2023: The Report U.S. Clinical Oncology Next Generation Sequencing Market Size, Share & Trends Analysis Report By Technology (Whole Genome Sequencing, Whole Exon Sequencing, Targeted Sequencing & Resequencing), By Workflow, By End Use, Regions, And Segment Forecasts 2018 To 2024 The U.S. clinical oncology next generation sequencing market is anticipated to reach USD 1.53…
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#U.S. Clinical Oncology Next Generation Sequencing Market#U.S. Clinical Oncology Next Generation Sequencing Market 2024#U.S. Clinical Oncology Next Generation Sequencing Market Share#U.S. Clinical Oncology Next Generation Sequencing Market Size
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Next Generation Sequencing Market 2024 Size, Share, Feasibility Status and Growth Outlook by 2032
The Next Generation Sequencing (NGS) market is poised for substantial growth, driven by advancements in genomic research, personalized medicine, and diagnostics. According to SNS Insider's latest research report, the NGS market is expected to experience significant revenue growth, propelled by the increasing adoption of NGS technologies in healthcare and life sciences. As of now, the market is valued at a notable figure, and its revenue trajectory is forecasted to expand substantially over the next few years. The increasing prevalence of genetic disorders, coupled with rising demand for precision medicine, is one of the driving factors behind this surge in NGS market revenue. Learn more about Next Generation Sequencing (NGS) Market Revenue
Next Generation Sequencing (NGS) technologies have revolutionized the field of genomics by enabling rapid and cost-effective sequencing of DNA and RNA. These innovations have significantly reduced the time and cost involved in sequencing, making it more accessible to researchers, clinicians, and healthcare providers. The integration of NGS into various healthcare applications, including disease diagnosis, drug development, and personalized treatment, has paved the way for a more precise and efficient approach to patient care. The global healthcare sector is now investing heavily in NGS platforms to support targeted therapies and enhance disease prevention.
The NGS market's rapid growth can be attributed to several key factors. The increasing focus on early diagnosis and personalized healthcare solutions is a major driver. NGS allows for a deeper understanding of an individual’s genetic makeup, enabling healthcare professionals to tailor treatment plans based on specific genetic profiles. Additionally, the growing awareness of the benefits of genetic testing, combined with an expanding pool of trained professionals, has further fueled market demand.
With the continued expansion of applications such as cancer genomics, infectious disease analysis, and rare genetic disorder diagnostics, NGS technology has become indispensable in clinical settings. Furthermore, the decreasing costs of sequencing, paired with advancements in bioinformatics, have made NGS even more accessible to a broader range of industries.
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The NGS market is divided into multiple segments based on technology, application, and end-users. Among these, the diagnostic application segment is expected to witness significant growth, with oncology applications being a prominent contributor. Cancer genomics, in particular, is one of the key areas benefiting from NGS technology, as it allows for more accurate detection of genetic mutations, which is crucial for targeted therapies. In addition to oncology, infectious diseases such as COVID-19, tuberculosis, and other viral infections are also being extensively studied using NGS, providing vital insights for public health monitoring and prevention strategies.
The technological advancements in NGS platforms, including single-cell sequencing, metagenomics, and CRISPR-based gene editing technologies, are further boosting market expansion. These innovations are opening up new research avenues and applications, thus propelling the growth of the NGS market. Moreover, the increasing availability of advanced bioinformatics tools, which aid in analyzing the large volumes of data generated by NGS, has further increased the technology's value in various fields of research and clinical practice.
Geographically, North America holds a significant share in the NGS market, with a strong presence of leading biotechnology and pharmaceutical companies. The region’s well-established healthcare infrastructure, along with the adoption of advanced technologies, has contributed to the dominance of North America in the NGS landscape. However, the Asia Pacific region is expected to grow at a faster rate, owing to factors such as rising healthcare investments, growing research activities, and the increasing prevalence of chronic diseases.
The competitive landscape of the NGS market is highly fragmented, with numerous key players vying for market share. Leading companies such as Illumina, Thermo Fisher Scientific, Pacific Biosciences, and Roche are at the forefront of developing cutting-edge NGS solutions. These players are focusing on technological advancements, strategic collaborations, and product innovations to strengthen their market positions. Furthermore, as the demand for NGS continues to rise, the industry is expected to see an influx of new players entering the market with novel solutions and services.
In conclusion, the Next Generation Sequencing market is on the cusp of significant growth, with advancements in technology and applications driving market dynamics. With the increasing demand for personalized medicine, early disease diagnosis, and genetic testing, the market's future looks promising. As NGS becomes more integrated into clinical settings and research labs, its potential to transform healthcare and life sciences is limitless.
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#Next Generation Sequencing Market#Next Generation Sequencing Market Size#Next Generation Sequencing Market Share#Next Generation Sequencing Market Growth#Market Research
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Tissue Diagnostics Market Growth Insights, Size, Share, Forecast 2024-2032 | S&S Insider
Tissue diagnostics is a critical field in medical diagnostics, providing detailed analysis of tissue samples to detect and diagnose diseases such as cancer, infections, and autoimmune disorders. This discipline leverages advanced imaging and molecular techniques to examine cellular structures and identify abnormalities at an early stage, aiding in more precise and timely clinical decisions. Tissue diagnostics has evolved with significant advancements in digital pathology, immunohistochemistry, and next-generation sequencing, enabling pathologists to gain clearer insights into cellular and molecular changes associated with disease progression.
The Tissue Diagnostics Market Size was valued at USD 5.5 billion in 2023, and is expected to reach USD 9.59 billion by 2031 and grow at a CAGR of 7.2% over the forecast period 2024-2031.
Future Scope
The future of tissue diagnostics is centered on integrating artificial intelligence (AI) and machine learning to enhance diagnostic accuracy and efficiency. AI-powered image analysis is expected to streamline tissue sample interpretation, allowing pathologists to rapidly identify patterns that might indicate malignancy or other abnormalities. Additionally, personalized diagnostics is emerging as a promising area, with tissue diagnostics being tailored to individual genetic profiles. This approach will likely increase the precision of treatments, particularly in oncology, making tissue diagnostics an essential tool in personalized medicine.
Trends
Key trends in tissue diagnostics include the rise of digital pathology, which enables remote analysis and data sharing among specialists, and advancements in multiplex assays, which allow for simultaneous detection of multiple biomarkers. Another important trend is the use of predictive biomarkers in diagnostics, which provides insights into how a patient’s disease might progress or respond to treatment. With growing focus on precision medicine, these trends are enabling more personalized and effective approaches to patient care.
Applications
Tissue diagnostics is widely used in oncology for diagnosing cancers, determining cancer stage, and assessing treatment efficacy. It is also essential in identifying infections and inflammatory diseases, as well as monitoring transplant rejection in post-surgical patients. In clinical research, tissue diagnostics helps in identifying specific genetic markers and biomarkers that guide new drug developments. Its versatility makes it a cornerstone in both clinical and research settings, delivering critical information for accurate diagnoses and therapeutic planning.
Key Points
Tissue diagnostics provides early detection of diseases like cancer, infections, and autoimmune disorders.
AI and machine learning are driving advancements in diagnostic accuracy.
Digital pathology facilitates remote analysis and collaboration.
Multiplex assays enable simultaneous detection of multiple biomarkers.
Tissue diagnostics is central to oncology, infection diagnosis, and personalized medicine.
Conclusion
Tissue diagnostics continues to advance, enabling healthcare providers to diagnose diseases with increased speed and accuracy. As technologies such as AI and digital pathology become integrated into routine diagnostics, tissue diagnostics will play a crucial role in early disease detection and treatment planning. This evolution not only enhances patient outcomes but also drives forward the capabilities of personalized medicine.
#Tissue Diagnostics Market#Tissue Diagnostics Market Size#Tissue Diagnostics Market Share#Tissue Diagnostics Market Growth#Tissue Diagnostics Market Report
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An Overview of Next Generation Sequencers Market: Trends and Insights
The Next-Generation Sequencers (NGS) market is witnessing rapid growth, driven by advancements in sequencing technology, declining costs, and increasing applications across healthcare, research, and agriculture. NGS enables high-throughput DNA sequencing, allowing for a more comprehensive analysis of genomes, transcriptomes, and epigenomes.
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This market encompasses various components, including instruments, software, and reagents, catering to a wide array of end-users, such as hospitals, research institutes, and biotechnology firms.
1. Market Overview
Market Size and Growth: The NGS market has shown robust growth due to rising demand for genomic analysis in personalized medicine, cancer research, and genetic diagnostics. Increasing adoption in clinical settings, along with advancements in technology, has driven accessibility and expanded market reach.
Regional Trends: North America and Europe currently dominate the market due to high healthcare expenditures, advanced infrastructure, and a significant focus on research and development. Meanwhile, Asia-Pacific is emerging as a promising market due to rising healthcare investments and increasing adoption of genomic medicine.
Key Applications: The major applications for NGS include oncology, infectious disease diagnostics, reproductive health, and hereditary disease screening, along with applications in agriculture and environmental studies.
2. Key Trends in the NGS Market
Declining Sequencing Costs: The costs of sequencing have significantly dropped since the advent of NGS technologies. The "thousand-dollar genome" has become a reality, making genetic testing more affordable and accessible, particularly in research and clinical diagnostics.
Shift Towards Clinical Applications: There is a growing demand for NGS in clinical settings, particularly in oncology for tumor profiling, hereditary disease detection, and pharmacogenomics. Clinical applications are gaining traction due to their potential for precision medicine, helping tailor treatments to individual genetic profiles.
Focus on Cancer Research: Oncology remains a major application area for NGS, as it enables detailed cancer genome analysis, leading to better understanding of mutations and tumor behavior. This technology supports both research and diagnostic applications, fueling demand among pharmaceutical companies and research institutes focused on oncology.
Rise of Liquid Biopsies: NGS is widely used in liquid biopsies, which offer a non-invasive method for cancer detection and monitoring by analyzing cell-free DNA (cfDNA) from blood samples. Liquid biopsies are gaining popularity as they allow real-time monitoring of tumor progression and treatment efficacy, reducing the need for invasive procedures.
Emergence of Long-Read Sequencing: Long-read sequencing technologies, such as those offered by Pacific Biosciences and Oxford Nanopore, are gaining traction due to their ability to provide more comprehensive genomic insights. These technologies are particularly valuable in detecting structural variants and resolving complex genomic regions.
Development of Companion Diagnostics: NGS-based companion diagnostics, used to determine the efficacy and safety of a specific drug for a targeted patient group, are expanding. These diagnostics guide treatment decisions in oncology, particularly for identifying biomarkers associated with certain therapies.
3. Market Segmentation
By Product: The NGS market includes sequencers, software, consumables, and services. Consumables, including reagents and kits, constitute the largest segment due to repeated purchases. However, software solutions are gaining traction as data analysis and interpretation become more complex.
By Technology:
Whole Genome Sequencing (WGS): WGS provides a comprehensive view of the entire genome, making it suitable for research and complex disease studies.
Targeted Sequencing: Targeted sequencing is cost-effective and focuses on specific regions of interest, widely used in oncology and clinical diagnostics.
RNA Sequencing: RNA sequencing enables transcriptome analysis and is valuable in cancer research, gene expression studies, and drug discovery.
Exome Sequencing: Exome sequencing, which targets protein-coding regions, is a more affordable alternative to WGS and is commonly used for diagnosing genetic disorders.
By Application: The NGS market serves several applications, including oncology, infectious disease diagnosis, reproductive health, genetic screening, and forensic analysis. Oncology holds the largest share, while infectious disease applications, particularly in tracking pathogens and outbreaks, are rapidly growing.
By End User: The primary end-users include academic and research institutions, hospitals and clinics, pharmaceutical and biotechnology companies, and government agencies. Hospitals and clinics are showing increasing demand as NGS technology moves from research into clinical diagnostics.
4. Key Drivers and Challenges
Drivers:
Increased Demand for Precision Medicine: The trend toward personalized medicine is a major driver, as NGS allows for tailored treatments based on genetic profiles, improving treatment outcomes.
Growing Investment in Genomic Research: Governments, healthcare institutions, and private companies are heavily investing in genomic research and infrastructure to support NGS applications across various fields.
Expansion of Genetic Screening Programs: Many countries are implementing large-scale genetic screening programs for early detection of genetic disorders and hereditary cancers, boosting demand for NGS.
Challenges:
Data Management and Analysis Complexity: The high volume of data generated by NGS requires advanced bioinformatics solutions for analysis, interpretation, and storage. This creates a need for skilled personnel and sophisticated software.
Regulatory and Ethical Concerns: The regulatory landscape for NGS is evolving, and concerns regarding data privacy and ethical issues are prevalent. Obtaining regulatory approval for clinical NGS applications can be time-consuming.
High Initial Investment: Although sequencing costs have decreased, the initial investment required for NGS platforms and bioinformatics infrastructure remains high, limiting adoption in resource-constrained regions.
5. Competitive Landscape
The NGS market is highly competitive, with established players as well as new entrants focusing on niche applications. Key players are investing in research and development, collaborations, and acquisitions to strengthen their market positions and expand product portfolios.
Illumina, Inc.: Illumina is the market leader, with a dominant position in sequencing instruments and consumables. Its sequencers, including the NovaSeq and NextSeq series, are widely used in research and clinical settings.
Thermo Fisher Scientific, Inc.: Known for its Ion Torrent platform, Thermo Fisher focuses on providing affordable, high-throughput sequencing solutions, with applications ranging from cancer research to infectious disease diagnostics.
Pacific Biosciences: PacBio specializes in long-read sequencing technology, particularly valuable for applications that require high accuracy in structural variant detection. Its Sequel system is popular among researchers in complex genomics.
Oxford Nanopore Technologies: Oxford Nanopore offers portable, real-time sequencing devices like the MinION and PromethION, which are particularly useful for field-based applications and rapid sequencing needs.
BGI Group: Based in China, BGI is a major player in genome sequencing services and provides a range of sequencers tailored for research and clinical applications. Its focus on affordability has helped it gain traction in emerging markets.
Qiagen N.V.: Qiagen provides NGS sample preparation and bioinformatics solutions, with a particular emphasis on clinical diagnostics. Its GeneReader NGS System is aimed at making NGS more accessible in clinical labs.
Agilent Technologies: Agilent offers NGS target enrichment and analysis solutions, focusing on workflows for oncology and hereditary disease testing.
6. Future Outlook
Advancements in Data Analysis Tools: Continued improvements in bioinformatics and artificial intelligence are expected to streamline data interpretation, making NGS more accessible to clinical users and reducing the time required for analysis.
Rise of Multi-Omics Approaches: Multi-omics, which combines genomics with proteomics, transcriptomics, and metabolomics, is expected to enhance the understanding of complex diseases. NGS will play a key role in integrating genomic data with other molecular insights.
Increased Focus on Rare Disease Research: NGS enables the identification of mutations associated with rare genetic disorders, facilitating research and development of targeted therapies. This area is likely to see continued growth, especially as pharmaceutical companies invest in precision medicine.
Expansion of Direct-to-Consumer (DTC) Testing: DTC genetic testing is gaining popularity, and as NGS becomes more affordable, companies may offer more comprehensive and affordable sequencing-based consumer tests.
Development of Point-of-Care Sequencing: Point-of-care NGS devices, offering rapid and portable sequencing capabilities, could find applications in emergency rooms and remote locations, particularly for infectious disease diagnosis.
Conclusion
The NGS market is positioned for substantial growth, driven by its expanding role in clinical diagnostics, advancements in sequencing technology, and increasing affordability. Applications in cancer research, infectious disease detection, and reproductive health are set to grow as the technology becomes more integrated into healthcare systems worldwide. However, challenges such as data complexity and regulatory hurdles will require ongoing innovation in bioinformatics and clear guidelines for clinical use. As technology advances, NGS has the potential to become a routine tool in personalized medicine, facilitating earlier diagnosis, better treatments, and improved patient outcomes across a range of medical fields.
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Competitive Landscape and Key Players in SNP Genotyping Market
The SNP genotyping and analysis market is witnessing remarkable growth, driven by advancements in genomics and an increasing focus on personalized medicine. SNP (single nucleotide polymorphism) genotyping identifies variations in a single nucleotide in a genome, aiding in the study of genetic predispositions to various diseases, drug responses, and genetic traits. This market includes the technologies, tools, and services used to genotype SNPs and conduct analysis, which has widespread applications in research, diagnostics, and drug development. The demand for SNP genotyping and analysis is particularly high in the fields of oncology, pharmacogenomics, and agricultural research, as it enables deeper insights into genetic variations and their impact on individual and population-level health outcomes.
The SNP Genotyping and Analysis Market Size was projected to reach $13.7 billion (USD billion) in 2022 based on MRFR analysis. It is anticipated that the market for SNP genotyping and analysis will increase from 15.11 billion USD in 2023 to 36.6 billion USD in 2032. During the forecast period (2024-2032), the SNP Genotyping and Analysis Market is anticipated to develop at a CAGR of approximately 10.33%.
SNP Genotyping and Analysis Market Share
The SNP genotyping and analysis market share is primarily held by leading companies like Illumina, Thermo Fisher Scientific, and Bio-Rad Laboratories, which offer state-of-the-art genotyping tools, reagents, and software solutions. These companies dominate the market due to their advanced platforms, broad research capabilities, and established partnerships with research and clinical institutions. New market entrants, however, are gaining a foothold by focusing on cost-effective, high-throughput genotyping solutions. The market share is also geographically diverse, with North America and Europe holding prominent shares due to extensive research funding and a large base of biotech companies, while Asia-Pacific is rapidly growing due to expanding healthcare and research infrastructure.
SNP Genotyping and Analysis Market Analysis
SNP genotyping and analysis market analysis indicates significant growth potential due to the rising prevalence of chronic diseases and the increasing demand for genomic data in clinical and research settings. The analysis also shows that innovations in high-throughput sequencing and bioinformatics are facilitating more efficient, cost-effective SNP genotyping. Technologies like microarray analysis and next-generation sequencing (NGS) are key drivers, providing rapid and accurate SNP data at a fraction of traditional costs. This market analysis highlights the impact of growing awareness of genetic testing among patients and healthcare providers, as well as increasing investments by governments and private entities in genomic research. The focus on personalized medicine, where treatments are tailored to individual genetic profiles, is expected to drive continuous demand in the SNP genotyping and analysis market.
SNP Genotyping and Analysis Market Trends
Key SNP genotyping and analysis market trends include the adoption of automation and AI in genomics. AI-powered data analysis helps interpret large datasets generated by SNP genotyping, enabling faster and more accurate insights into genetic associations. Another trend is the increased use of SNP genotyping in non-invasive prenatal testing (NIPT) and newborn screening, which has become an essential aspect of early disease diagnosis and prevention. Furthermore, the integration of genotyping and bioinformatics platforms enables researchers to conduct more comprehensive analyses, streamlining the identification of disease-related SNPs. The growing interest in consumer genomics, where individuals can gain insights into their ancestry and health risks through direct-to-consumer (DTC) testing kits, is also impacting the SNP genotyping and analysis market.
Reasons to Buy the Reports
Market Insights and Forecasts: Detailed projections on the SNP genotyping and analysis market, including future opportunities and growth drivers.
Competitive Landscape: Comprehensive information on market share and strategic positioning of key players, enabling informed decision-making.
Technological Trends: Insights into the latest technological advancements, such as AI integration, next-generation sequencing, and bioinformatics tools in SNP genotyping.
Regional Analysis: Regional breakdowns and growth potential insights to help investors and companies identify high-opportunity areas globally.
Personalized Medicine Focus: Analysis of the expanding role of SNP genotyping in personalized medicine, highlighting its applications in oncology, pharmacogenomics, and genetic testing.
Recent Developments
Recent developments in the SNP genotyping and analysis market reflect a focus on expanding applications and improving technology. In 2023, Thermo Fisher Scientific launched a new NGS-based genotyping platform designed for high-accuracy pharmacogenomic research, enhancing its utility in personalized medicine. Illumina introduced a cost-effective array platform targeting SNP genotyping for agricultural genomics, providing a tailored solution for crop and livestock breeding. Additionally, Bio-Rad Laboratories announced a strategic collaboration to integrate its genotyping software with AI-powered bioinformatics tools, improving analysis speed and accuracy. Advancements in point-of-care (POC) genotyping devices have also been significant, allowing for rapid SNP analysis in clinical settings and contributing to the increased demand in the SNP genotyping and analysis market.
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Understanding the Cancer Microbiome: A New Frontier in Oncology
The global cancer microbiome market size was USD 222.79 Million in 2022 and is expected to register a steady revenue CAGR of 19.9% during the forecast period, according to latest analysis by Emergen Research. Rising prevalence of cancer is a major factor driving market revenue growth. Microbiome is a collection of bacteria that live in and on human body, which have potential to affect initiation, progression, and treatment response of cancer, including cancer immunotherapy.
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Competitive Terrain:
The global Cancer Microbiome industry is highly consolidated owing to the presence of renowned companies operating across several international and local segments of the market. These players dominate the industry in terms of their strong geographical reach and a large number of production facilities. The companies are intensely competitive against one another and excel in their individual technological capabilities, as well as product development, innovation, and product pricing strategies.
The leading market contenders listed in the report are:
CD Genomics, Eurofins Scientific, Illumina, Inc., Prescient Medicine Holdings, Inc., Micronoma Inc., Novogene Co., Ltd., Oxford Nanopore Technologies plc., Pacific Biosciences of California, Inc., QIAGEN N.V., and Thermo Fisher Scientific Inc
Key market aspects studied in the report:
Market Scope: The report explains the scope of various commercial possibilities in the global Cancer Microbiome market over the upcoming years. The estimated revenue build-up over the forecast years has been included in the report. The report analyzes the key market segments and sub-segments and provides deep insights into the market to assist readers with the formulation of lucrative strategies for business expansion.
Competitive Outlook: The leading companies operating in the Cancer Microbiome market have been enumerated in this report. This section of the report lays emphasis on the geographical reach and production facilities of these companies. To get ahead of their rivals, the leading players are focusing more on offering products at competitive prices, according to our analysts.
Report Objective: The primary objective of this report is to provide the manufacturers, distributors, suppliers, and buyers engaged in this sector with access to a deeper and improved understanding of the global Cancer Microbiome market.
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Market Segmentations of the Cancer Microbiome Market
This market is segmented based on Types, Applications, and Regions. The growth of each segment provides accurate forecasts related to production and sales by Types and Applications, in terms of volume and value for the period between 2022 and 2030. This analysis can help readers looking to expand their business by targeting emerging and niche markets. Market share data is given on both global and regional levels. Regions covered in the report are North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. Research analysts assess the market positions of the leading competitors and provide competitive analysis for each company. For this study, this report segments the global Cancer Microbiome market on the basis of product, application, and region:
Segments Covered in this report are:
Techniques Outlook (Revenue, USD Million; 2019-2032)
Next Generation Sequencing
Polymerase Chain Reaction
Others
End-use Outlook (Revenue, USD Million; 2019-2032)
Hospitals
Clinic
Others
Regional Outlook (Revenue, USD Million; 2019–2032)
North America
U.S.
Canada
Mexico
Europe
Germany
France
UK
Italy
Spain
Benelux
Rest of Europe
Asia Pacific
China
India
Japan
South Korea
Rest of APAC
Latin America
Brazil
Rest of LATAM
Middle East & Africa
Saudi Arabia
UAE
South Africa
Turkey
Rest of Middle East & Africa
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Major Geographies Analyzed in the Report:
North America (U.S., Canada)
Europe (U.K., Italy, Germany, France, Rest of EU)
Asia Pacific (India, Japan, China, South Korea, Australia, Rest of APAC)
Latin America (Chile, Brazil, Argentina, Rest of Latin America)
Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of MEA)
ToC of the report:
Chapter 1: Market overview and scope
Chapter 2: Market outlook
Chapter 3: Impact analysis of COVID-19 pandemic
Chapter 4: Competitive Landscape
Chapter 5: Drivers, Constraints, Opportunities, Limitations
Chapter 6: Key manufacturers of the industry
Chapter 7: Regional analysis
Chapter 8: Market segmentation based on type applications
Chapter 9: Current and Future Trends
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Clinical Oncology Next Generation Sequencing Market 2024 : Size, Growth Rate, Business Module, Product Scope, Regional Analysis And Expansions 2033
The clinical oncology next generation sequencing global market report 2024 from The Business Research Company provides comprehensive market statistics, including global market size, regional shares, competitor market share, detailed segments, trends, and opportunities. This report offers an in-depth analysis of current and future industry scenarios, delivering a complete perspective for thriving in the industrial automation software market.
Clinical Oncology Next Generation Sequencing Market, 2024 report by The Business Research Company offers comprehensive insights into the current state of the market and highlights future growth opportunities.
Market Size - The clinical oncology next generation sequencing market size has grown rapidly in recent years. It will grow from $0.45 billion in 2023 to $0.52 billion in 2024 at a compound annual growth rate (CAGR) of 15.5%. The growth in the historic period can be attributed to genomic research advances, cancer biomarker discovery, technological advancements, regulatory approvals.
The clinical oncology next generation sequencing market size is expected to see rapid growth in the next few years. It will grow to $0.86 billion in 2028 at a compound annual growth rate (CAGR) of 13.2%. The growth in the forecast period can be attributed to growing cancer incidence, precision medicine, immuno-oncology, liquid biopsies. Major trends in the forecast period include comprehensive genomic profiling (cgp), immuno-oncology, tumor evolution and heterogeneity, ai and machine learning.
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The Business Research Company's reports encompass a wide range of information, including:
1. Market Size (Historic and Forecast): Analysis of the market's historical performance and projections for future growth.
2. Drivers: Examination of the key factors propelling market growth.
3. Trends: Identification of emerging trends and patterns shaping the market landscape.
4. Key Segments: Breakdown of the market into its primary segments and their respective performance.
5. Focus Regions and Geographies: Insight into the most critical regions and geographical areas influencing the market.
6. Macro Economic Factors: Assessment of broader economic elements impacting the market.
Market Drivers - The rise in the number of cancer cases across the globe is likely to contribute to the growth of the clinical oncology next-generation sequencing market during the forecast period. According to the American Cancer Society, there were 1.9 million new cases and 0.6 million cancer deaths in 2021 in the USA. The four most common types of cancer worldwide are lung, prostate, bowel, and female breast cancer, accounting for 43% of all the new cancer cases. Therefore, the rise in cancer incidence rate globally is anticipated to boost the demand for the growth of the clinical oncology next-generation sequencing market.
The clinical oncology next generation sequencing market covered in this report is segmented –
1) By Technology: Ion Semiconductor Sequencing, Pyro-Sequencing, Synthesis Sequencing, Real Time Sequencing, Ligation Sequencing, Reversible Dye Termination Sequencing, Nano-Pore Sequencing 2) By Application: Screening, Companion Diagnostics, Other Diagnostics 3) By End User: Hospital Laboratories, Clinical Research Organizations, Diagnostic laboratories
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Regional Insights - North America was the largest region in the clinical oncology next-generation sequencing market in 2023. Asia-Pacific was the second largest region in the clinical oncology next-generation sequencing market. The regions covered in the clinical oncology next generation sequencing market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa
Key Companies - Major companies operating in the clinical oncology next generation sequencing market include Thermo Fisher Scientific, Oxford Nanopore Technologies Ltd., QIAGEN N.V., Myriad Genetics Inc., Illumina Inc., F. Hoffmann-La Roche Ltd., PerkinElmer Inc., Agilent Technologies Inc., Pacific Biosciences of California Inc., Caris Life Sciences, Paradigm Diagnostics, GATC Biotech AG, Macrogen Inc., DNASTAR Inc., Exosome Diagnostics Inc., Biomatters Ltd., Partek Inc., Foundation Medicine Inc., Becton Dickinson and Company (BD), Takara Bio Inc., Creative Biolabs, Mogene LC, Knome Inc., Genomatix Software GmbH, CLC bio, GnuBIO Inc., Bio-Rad Laboratories Inc., BGI Genomics Co. Ltd., Guardant Health Inc., Invitae Corporation, Natera Inc., NeoGenomics Laboratories Inc., Sysmex Corporation, Veracyte Inc., Zymo Research Corporation, ArcherDX Inc., Cepheid, Karius Inc., OncoDNA S.A., Personal Genome Diagnostics Inc., PierianDx Inc.
Table of Contents 1. Executive Summary 2. Clinical Oncology Next Generation Sequencing Market Report Structure 3. Clinical Oncology Next Generation Sequencing Market Trends And Strategies 4. Clinical Oncology Next Generation Sequencing Market – Macro Economic Scenario 5. Clinical Oncology Next Generation Sequencing Market Size And Growth ….. 27. Clinical Oncology Next Generation Sequencing Market Competitor Landscape And Company Profiles 28. Key Mergers And Acquisitions 29. Future Outlook and Potential Analysis 30. Appendix
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https://www.maximizemarketresearch.com/market-report/clinical-oncology-next-generation-sequencing-market/100383/
The Clinical Oncology Next-Generation Sequencing Market size was valued at USD 9.49 Billion in 2023 and the total Clinical Oncology Next-Generation Sequencing revenue is expected to grow at a CAGR of 20.7 % from 2024 to 2030, reaching nearly USD 35.42 Billion by 2030.
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Companion Diagnostic Market Key Players, Dynamics & Latest Trades Report to 2032
Companion Diagnostic Market Report has recently added by Value Market Research, this surveillance report establishing the facts based on current scenarios, historical records from 2023 to future forecast upto 2032. This report explicit data of various outlook such as market share, size, growth rates, and industry opportunities and offering an economical advantage for business success. It furnish the 360-degree overview of the competitive landscape of the global industries. Porter’s Five Forces Model analysis has been used to understand the industry’s structure, strength, weaknesses, opportunities, threats and challenges in front of the businesses.
The research report also covers the comprehensive profiles of the key players in the market and an in-depth view of the competitive landscape worldwide. The major players in the companion diagnostics market include Abbott Laboratories Molecular, Inc., Agilent, ARUP Laboratories, Inc., BioMerieux SA, Danaher Corporation. This section includes a holistic view of the competitive landscape that includes various strategic developments such as key mergers & acquisitions, future capacities, partnerships, financial overviews, collaborations, new product developments, new product launches, and other developments.
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Market Dynamics
Companion diagnostics are a crucial part of personalized medicine and will likely continue to rapidly increase in the number of disease areas. The next generation of drugs has to be safer and more efficacious. Companion diagnostics are one of the tools that can generate this information and make it available to drug developers. Escalating activities of drug discovery and vaccine development will be driving the market growth. Oncology is a segment of major focus and will remain at the forefront for the foreseeable future. Companion diagnostic play a major role in oncology research and has revolutionized the treatment of cancer by allowing doctors to adjust drug therapy to achieve better clinical results. However, the high cost and uncertain reimbursement scenario in a different region are hampering the growth of the market.
The report covers Porter’s Five Forces Model, Market Attractiveness Analysis and Value Chain analysis. These tools help to get a clear picture of the industry’s structure and evaluate the competition attractiveness at a global level.
Additionally, these tools also give inclusive assessment of each application/product segment in the global market of companion diagnostics.
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Market Segmentation
The entire companion diagnostics market has been sub-categorized into technology type, and indication. The report provides an analysis of these subsets with respect to the geographical segmentation. This research study will keep marketer informed and helps to identify the target demographics for a product or service.
By Technology Type
Immunohistochemistry
Polymerase Chain Reaction
Next Generation Sequencing
In Situ Hybridization
Others
By Indication
Oncology
Neurology
Others
Regional Analysis
This section covers regional segmentation which accentuates on current and future demand for companion diagnostics market across North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. Further, the report focuses on demand for individual application segment across all the prominent regions.
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The U.S. clinical oncology next generation sequencing market size was estimated at USD 166.9 million in 2022 and is expected to surpass around USD 687.04 billion by 2032 and poised to grow at a compound annual growth rate (CAGR) of 15.2% during the forecast period 2023 to 2032.
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Digital PCR Market - Forecast(2024 - 2030)
Digital PCR Market Overview
Digital PCR Market size is forecast to reach $8.2 billion by 2026, growing at a CAGR of 9.3% during the forecast period 2021-2026. Digital Polymerase chain reaction is used for detection of nucleic acid that provides a reproducible and sensitive way to measure the amount of RNA present. It depicts high potential in clinical diagnostics, and forensics along with the in-vitro amplification of any DNA sample. It is also used for detection of viruses in cerebrospinal fluid of patients that are having neurological disease. The main advantage of digital PCR is that it has high tolerance to inhibitors, play an important role in targeted next-generation sequencing, and it also measures the cancer genes. It has various application in paternity testing and DNA cloning. Rise in prevalence of infectious disease and surge in awareness & acceptance of personalized medicines are the major factors driving the growth of the market. Advancement in technique and growing market penetration is set to further enhance the overall market development of the Digital PCR Market for the period 2021-2026.
Report Coverage
The report: “Digital PCR Market Forecast (2021-2026)”, by Industry ARC, covers an in-depth analysis of the following segments of the Digital PCR Market.
By Product: Consumables & Reagents and Software & Services
By Technology Type: Droplet Digital PCR, Chip Based Digital PCR, and Beaming Digital PCR
By Indication: Infectious Disease, Oncology, Genetic Disorders, and Others
By Application: Research, Clinical Diagnostics, Forensics, and Others
By Geography: North America (U.S., Canada, Mexico), Europe (Germany, United Kingdom (U.K.), France, Italy, Spain, Russia, and Rest of Europe), Asia Pacific (China, Japan India, South Korea, Australia, and New Zealand, and Rest of Asia Pacific), South America (Brazil, Argentina, and Rest of South America), and Rest of the World (Middle East, and Africa)
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Key Takeaways
North America dominated the Digital PCR Market in 2020 owing to the increasing demand for rapid diagnostic tests and high diagnosis rates for infectious disease. The Digital PCR Market scope for different regions will be provided in the final report.
Technological advancements in digital PCR and growing adoption of digital PCR over real time PCR are likely to aid the market growth of the Digital PCR Market report.
Detailed analysis of the Strength, Weakness, and Opportunities of the prominent players operating in the market will be provided in the Digital PCR Market report.
High cost of digital PCR devices and reimbursement issues along with the technical limitations of PCR is poised to create hurdles for the Digital PCR Market.
Digital PCR Market Segment Analysis – By Technology Type
Droplet Digital PCR held the largest share in the Digital PCR Market in 2020 and is estimated to grow at a CAGR of 9.7% during the forecast period 2021-2026. This is attributed to the technological advances along with various new product launches. Droplet digital PCR is based on water oil emulsion droplet technology and for the amplification of the template molecules in each individual droplet. It also uses workflows and reagents for most standard probe based assays. Droplet digital PCR also measure the copy number variation by partitioning a PCR reaction into nanoliter droplets. The cross-contamination drawback of droplet digital PCR is increasing the demand of chip based digital PCR. Droplet digital PCR are estimated to register the highest CAGR over the period 2021-2026.
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Digital PCR Market Segment Analysis – By Indication
Infectious disease held the largest share in the Digital PCR Market in 2020 and is estimated to grow at a CAGR 8.6% during the forecast period 2021-2026. This is attributed to the advantages of the droplet digital PCR of infectious diseases such as bacterial, viral, and parasitic indications. Digital PCR provides more accurate, sensitive, and reproductive detection of pathogens according to the National Center for Biotechnology and it is better than real time polymerase chain reaction that are used for clinical diagnostics. The demand of oncology is increasing owing to the growing prevalence of the condition and introduction of new product launches. Oncology are estimated to register the highest CAGR over the period 2021-2026.
Digital PCR Market Segment Analysis – By Geography
North America dominated the Digital PCR Market with a major share of 37.6% in 2020. This is attributed to the high prevalence & diagnosis rates for infectious disease and high awareness among patient population towards new diagnostic options. Availability of digital PCR devices, rising incidences of various types of cancer and metabolic diseases requiring advanced diagnosis and therapeutics is also increasing the growth of the market in this region.
However, Asia Pacific is estimated to grow at a higher CAGR during the forecast period 2021-2026 owing to the growing patient awareness regarding advanced digital polymerase chain reaction devices. Developing Healthcare infrastructure is also increasing the growth of the market in this region.
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Digital PCR Market Drivers
Technological Advancements in Digital PCR
Technological advancements in digital PCR is increasing the growth of the Digital PCR Market. This is attributed to the growing demand for innovative devices and increasing research & development activities. Digital PCR is used to quantify and amplify nuclei acid. The introduction of various technologically advanced devices such as droplet digital PCR, chip based, and beam digital PCR is offering great benefits to the market. Thus, increasing the growth of the Digital PCR Market during the forecast period 2021-2026.
Growing Adoption of Digital PCR over Realtime PCR
Growing adoption of digital PCR over Realtime PCR is increasing the growth of the Digital PCR Market. This is attributed to the fact that digital PCR helps to deliver a compete measure to target nucleic acid molecules that is achieved from real time PCR. DNA quantification allows for reproducibility, precision, and sensitive that enables the researches to quantify smaller differences and measure minor variants very precisely. Thus, increasing the growth of the Digital PCR Market during the forecast period 2021-2026.
Digital PCR Market Challenges
High Cost of Digital PCR Devices and Reimbursement Issues Along with the Technical Limitations of PCR
Some of the factors that are set to impede the growth of the Digital PCR Market are high cost of digital PCR devices and reimbursement issues along with the technical limitations of PCR. The adoption of digital polymerase chain reaction techniques is limited owing to the lack of awareness about the digital PCR and the use of its advanced types.
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Digital PCR Market Landscape
Product launches, mergers and acquisitions, joint ventures, and R&D activities are key strategies adopted by players in the Digital PCR Market. In 2020, the Digital PCR Market share is consolidated by the top ten players present in the market. Digital PCR Market, top 10 companies are Thermo Fisher Scientific Inc., BioMerieux SA, Stilla Technologies, Merck KgaA, Combinati Inc., and Bio-Rad Laboratories among others.
Acquisitions/Product Launches
In 2020, BioMerieux SA received approval for Sars COV-2 gene tests that includes saliva specimens.
#Digital PCR Market#Digital PCR Market Size#Genetic Disorders#Digital PCR Industry#Oncology#Digital PCR Market Share#cerebrospinal fluid#Digital PCR top 10 companies#Digital PCR Market Report#Digital PCR Industry Outlook
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NGS based RNA Sequencing Market Technology Growth, Supply Demand and Analysis By Types 2024-2032
The global Next-Generation Sequencing (NGS)-based RNA sequencing market is positioned for robust growth, with the market size valued at USD 2.9 billion in 2023 and projected to reach USD 12.1 billion by 2032. This growth reflects a compound annual growth rate (CAGR) of 17.1% over the forecast period from 2024 to 2032, driven by advancements in genomics research, precision medicine, and rising demand for RNA-based diagnostics and therapeutics.
NGS-based RNA sequencing is a powerful tool for studying gene expression, transcriptome profiling, and identifying novel RNA sequences. It provides unparalleled insight into the mechanisms of gene regulation, disease progression, and therapeutic targets, making it indispensable in both research and clinical settings.
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Key Market Drivers
Advancements in Genomics and Transcriptomics Research: The rapid advancements in genomics research, coupled with the decreasing costs of sequencing technologies, are driving the adoption of NGS-based RNA sequencing. These advancements have revolutionized how scientists study gene expression, alternative splicing, and RNA editing, leading to breakthroughs in areas such as oncology, neurology, and immunology. The technology’s ability to provide high-resolution data on the transcriptome has fueled its widespread adoption in both academic research and pharmaceutical R&D.
Growing Application in Precision Medicine: Precision medicine, which aims to tailor treatments to individual genetic profiles, is another major driver of the market. NGS-based RNA sequencing allows for the comprehensive profiling of patients' transcriptomes, identifying specific biomarkers and therapeutic targets. This personalized approach is particularly valuable in cancer treatment, where RNA sequencing is used to identify mutations and gene fusions that can guide the selection of targeted therapies.
Rising Demand for RNA-Based Therapeutics and Vaccines: The success of mRNA vaccines during the COVID-19 pandemic has sparked increased interest in RNA-based therapeutics and vaccines. RNA sequencing plays a critical role in the development and optimization of these treatments, allowing researchers to study RNA expression patterns and develop effective interventions. The growing focus on RNA-based drug development is expected to drive further demand for NGS-based RNA sequencing.
Technological Innovations and Cost Reduction: Continuous innovations in sequencing technology, data analysis tools, and bioinformatics are making NGS-based RNA sequencing more accessible and cost-effective. New platforms that offer higher throughput, improved accuracy, and reduced turnaround times are enabling broader adoption across various research and clinical applications. As sequencing costs continue to decline, more institutions are expected to integrate NGS into their workflows, further driving market growth.
Expansion of RNA Sequencing in Clinical Diagnostics: RNA sequencing is increasingly being utilized in clinical diagnostics, particularly for cancer and rare genetic diseases. The technology enables the identification of gene expression changes, RNA fusions, and novel transcripts, which can be critical for diagnosing and stratifying patients based on their molecular profiles. As more RNA-based diagnostic tests receive regulatory approval, the demand for NGS-based RNA sequencing in clinical laboratories is expected to rise significantly.
Challenges and Opportunities
Despite its promising outlook, the NGS-based RNA sequencing market faces challenges such as the complexity of data interpretation, the need for advanced bioinformatics tools, and the integration of large-scale sequencing data into clinical workflows. Additionally, the high initial investment in sequencing infrastructure may pose barriers for smaller institutions.
However, these challenges are creating opportunities for innovation, particularly in the development of user-friendly bioinformatics platforms and cloud-based data analysis solutions. Collaborations between sequencing companies, software developers, and healthcare providers are expected to streamline the use of RNA sequencing in clinical settings, making it more accessible and scalable.
Regional Insights
North America holds the largest share of the NGS-based RNA sequencing market, driven by strong research funding, the presence of leading biotechnology companies, and the widespread adoption of precision medicine. The United States, in particular, has seen rapid advancements in cancer genomics and RNA therapeutics, fueling demand for RNA sequencing technologies.
Europe follows closely, with significant investments in genomic research and growing demand for RNA sequencing in both academic and clinical settings. The Asia-Pacific region is expected to experience the highest growth rate over the forecast period, supported by increasing healthcare investments, expanding research infrastructure, and the adoption of advanced sequencing technologies in countries like China, Japan, and India.
Future Outlook
The future of the NGS-based RNA sequencing market looks highly promising, with continued advancements in genomics, transcriptomics, and personalized medicine driving demand. As technology evolves and costs decline, RNA sequencing will become an integral tool in diagnosing, treating, and understanding complex diseases at the molecular level.
The market is set to expand rapidly, growing from USD 2.9 billion in 2023 to USD 12.1 billion by 2032, with a projected CAGR of 17.1% over the forecast period. As the integration of RNA sequencing into clinical practice accelerates, it will unlock new opportunities for innovation in healthcare, research, and drug development.
In conclusion, the NGS-based RNA sequencing market is poised for significant growth as technological advancements, rising applications in precision medicine, and increasing demand for RNA-based diagnostics and therapeutics reshape the landscape of healthcare and life sciences.
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