#Cellulose Acetate Butyrate Industry
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#Cellulose Acetate Butyrate (CAB) Market#Cellulose Acetate Butyrate (CAB) Market Trends#Cellulose Acetate Butyrate (CAB) Market Growth#Cellulose Acetate Butyrate (CAB) Market Industry#Cellulose Acetate Butyrate (CAB) Market Research#Cellulose Acetate Butyrate (CAB) Market Report
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Lupine Publishers| Contact Lens Materials and Modalities
Lupine Publishers| Ophthalmology Open Access Journal
Abstract
Introduction: Past two decades have seen a steep rise in the usage of contact lenses and that brought a major revolution in the materials research, design and manufacturing technologies. This also impacted the optometrists thus influencing the patient usage, modalities and duration. The current article briefs the changes in the field of contact lenses and the changing trends.
Methods: Contact lens materials and its manufacturing, wearing modalities and changing trends in prescribing them were identified, reviewed and summarized as per the topic requirements from scientific papers, authentic articles, books and websites to cover the challenges our ancestors have faced and the solutions that were provided in the past were summarized for the reader in an easy accessible way.
Conclusion: Newer generation of contact lens materials made an average contact lens wearer comfortable by wearing lenses for longer hours without discomfort and with minimal complications. Due to the advent of newer lens materials, practitioners have been given more options for choosing a best suited lens based on specific wearer requirements and needs. In this way, newly available materials and designs make the lens wear safer and less prone to complications by shifting the patient from conventional to planned replacement lenses (PRL) and from PRL to daily disposables to ensure a healthy and safer vision.
Keywords: PMMA; Rigid Gas Permeable Lenses; HEMA; Silicone Hydrogels; Extended Wear; Flexible Wear; Daily Disposables; Multifocal Contact Lenses; Aspheric; Toric
Abbreviation: CAB: Cellulose Acetate Butyrate; RGP: Rigid Gas Permeable Lens; P-HEMA: Poly Hydroxy Ethyl Methacrylate; PVP: Poly Vinyl Pyrolidone
Introduction
Contact lenses are medical devices commonly used to correct the vision without the need of spectacles. Even though the concept was very old, till 1887, a structure similar to our today's contact lens was not made. A first contact lens like structure was made in 1887 by F. A Muller by blowing glass to make a prosthetic eye. In 1930's a first contact lens made up of glass was used which covers whole the cornea and a small part of sclera was used for vision correction making glass the first contact lens material [1]. In 1937, a material named Poly methyl methacrylate (PMMA) was introduced as a contact lens material which mimics todays' scleral lens of a larger diameter. In 1948, Kevin Tuohy made a contact lens called "Microlens" which covers only cornea with 10 to 12 mm diameter [1,2]. After using PMMA as a contact lens material for some time, hypoxic complications arise due to it’s very poor oxygen permeable nature after use, making.com to explore for newer lens materials. Currently, due to its zero-oxygen permeability, it is used to make diagnostic trial contact lenses instead of actual contact lenses due to its ability to retain the parameters, ease of care and maintenance [3].
Rigid Gas Permeable Lenses (RGP)
Noting the importance of Oxygen permeability, few developments were made to the material to be permeable to oxygen. In the year 1972, Cellulose acetate butyrate (CAB) was proposed as a material to use by Irving Fatt, later in 1978 CAB as a contact lens material got FDA approved. A term (RGP) Rigid gas permeable lens was coined and the lens made with this (CAB) material was manufactured in 1978 in United States [2,4]. In the advent of silicone usage in the medical industry, Siloxane methacrylate material was developed in 1970 by using silicone molecules bonded to methyl methacrylate structures making a contact lens more oxygen permeable [2]. Siloxane acrylates material was patented in 1974 under the name Polycon and was introduced commercially in 1979 which lead the wearing time longer than CAB due to its high oxygen permeability without showing any hypoxic changes in the cornea. However, it was observed that the siloxane acrylate lenses tend to attract more of lipid and less of protein deposits on the lens surface, making the care and regime of newer RGP lens materials different than the previous lens. These deposits lead to lesser lens life than the previous lenses [2].
"Boston" a contact lens material manufacturing company started to develop working towards parameters like oxygen permeability, strength and deposit resistance for improved lens on eye performance since 1972. Elements Fluorine and Carbon were used in specific proportions to synthesize Fluoro-siloxane acrylates and Fluorocarbon acrylates were found effective in controlling the lipid deposits to occur on the lens surface with increased oxygen permeability. These materials still stand good in terms of availability, deposit resistance with good oxygen permeability [5]. Addition of Silicone, Fluorine and Carbon with appropriate amounts made it possible to achieve highest levels of oxygen permeability ever, leading to continuous wear, flexible wear and extended wear modalities possible. During this period in 1987, Fluoro-silicone acrylate material was made available [6]. Due to changing trends in the contact lens market and due to innovations in soft contact lens materials, there is a constant and a sharp decline in the RGP wearers that was observed in the past two decades due to the comfort achieved by soft contact lenses [7].
Silicone Elastomer
In 1956, Silicone elastomer material was developed by Walter Becker which has a highest ever oxygen permeability which is more flexible than RGP lenses, making the contact lens industry to explore newer ways of improvising the lens material in terms of flexibility But, for a product to manufacture out of silicone elastomer was not possible at that time due to its flexible nature, poor wettability and the material adheres to the cornea(suction). Later in 1981 a lens made up of silicone elastomer material was commercialized for correcting children to use as an overnight wear lens due to its exceedingly high oxygen permeability. This material got approved for 30 day continuous wear for non-aphakic prescriptions in 1983 making it the first extended wear lens to be produced [6,8]. Till now these elastomer lenses are available as a mode of correction for aphakia (congenital and acquired) cases mostly in children [9]. The only drawback with these lenses is the brittleness of the material and affinity to attract lipid deposits, making its usage declined in this decade [6,8].
Soft Contact Lens (Hydrogels)
Progress in contact lens materials was extremely rapid and the market equations of using RGP lenses were quickly changed after the development of Poly hydroxy ethyl methacrylate (P-HEMA) as a lens material in 1963 by Otto Wichterle. This material coined a new term called "soft contact lens" due to its soft and flexible nature. The lens made with HEMA was available in 1971 as a commercial product [2,6]. The usage of HEMA as a lens material in the current contact lens market still holds good. After the invention of HEMA as a hydrogel material, the comfort obtained by a wearer lead the path for a term called intermittent contact lens wear, which is not possible with RGP due to the discomfort it caused to an average wearer. However, the water content which is the only source of oxygen transmission through the hydrogel lens was too less when compared to RGP lenses due to their movement and tear exchange. There is a need for a diverse care and regime to be followed to soft contact lens wearers for which different contact lens solutions were devised to clean, rinse, disinfect, and hydrate and to store these lenses.
Due to limitation of water content and oxygen permeability in hydrogel lenses, there were diverse complications that were seen in the soft contact lens users and the users due to the comfort of the lenses, tend to sleep with the lenses on the cornea making the condition more worsen [10]. Observing these diverse ocular changes, few of the traditional RGP practitioners were reluctant to shift their practice and keep on dispensing RGP lenses only [11]. As there is a limitation in increasing the water content that we achieve with hydrogel lenses, scientists started to explore new ways to increase the oxygen passing through the lens which can enable the wearer to achieve better comfort lens with lesser complications [12]. Concept of Disposable soft contact lenses came into the field in 1985-1986 as the increasing complications can be counteracted by discarding the lenses before the deposits on the lens surface become sufficient enough to create problems like discomfort, bulbar conjunctival redness, allergic reactions in the upper tarsal conjunctiva and lack of oxygen supply due to deposits [13]. Gradually, frequent replacement lenses were so frequently replaced due to increasing in water content of the lenses that there is a need for a modality termed Daily disposable lenses in 1994-1995 to ensure maximum comfort and good ocular health with no requirement of care and maintenance which is a boon for existing, new contact lens wear. As the production need to meet the consumer needs a new manufacturing method called cast moulding turned the disposable modality a practically possible reality [2,14].
Even now, majority of the contact lens market share in developing countries is still contributing to Hydrogel lenses where as in developed countries, majority of the population is using silicone hydrogels and daily disposable hydrogel lenses for their visual needs [15-17]. In this stage, Silicone elastomers were more easily available and used in the market as a commercial product leading the materials science experts to turn their vision towards it. This change made them to think and combine the silicone with hydrogel lenses which set a stage for the generation of silicone hydrogels. The first silicone hydrogel lens was marketed in 2002 [2,9].
Silicone Hydrogels
In soft contact lenses the silicone material is incorporated based on the skeletal structures of classical hydrogel materials like HEMA and thereby making it a better lens material by incorporating:
a) OH groups for increasing the bound water content of the lens materials [18]
b) Materials like polyvinyl pyrolidone (PVP) for improving the wettability of the lenses [18]
Due to the innovation of Silicone hydrogel contact lenses, high oxygen transmissibility is made possible, hence by minimizing corneal hypoxia changes that include corneal oedema, Descemet’s membrane folds, microcysts, limbal hyperaemia and neovascularisation [19]. There are a few patient related .difficulties with these new lenses due to increased stiffness than existing hydrogels, hydrophobic nature and more attraction of lipid deposits. So, there is a need for a better and improved materials and designs making them readily acceptable by the patient [9]. In 2010, Custom made silicone hydrogel lenses are made available in the market [20]. In case of Silicone hydrogel lenses, these inventions can be technically classified into three phases in which the lens materials are synthesized by not only decreasing the stiffness of the lens material, but also by increasing the wettability and water content to a desired level for enhancing the comfort level of silicone hydrogel wearer equal to that achieved by a hydrogel contact lens wearer [18,19,21,22].
Developments in Silicone Hydrogel Materials
Table 1: First generation lenses.
1. Good Dk
2. Slightly stiffer
3. Deposit prone surface
4. Decreased Wettability
Table 2: Second generation lenses
b) Properties (Table 2)
2. Flexible lens material
1. Improved wettability
c) Properties (Table 3)
Table 3: Third generation lenses.
1. Better Water content
2. Decrease stiffness
3. It is a Breakthrough technology, which redefines the soft contact lens relationship between Dk and water content by having a higher Dk than water content predicts!
Contact lens advancements in the Future
a) Myopia control contact lenses are very soon going to be available in Asian countries where Myopia is more prevalent.
b) Aberrometers values combined with prescription can help customize the correction to a personalized contact lens manufacturing is possible soon [23].
c) A Multifocal design of contact lens which can have an autofocus capability near the pupillary centres of the eyes using fluid dynamics can be manufactured and fitted which can help.com gain complete visual satisfaction to the wearer [23].
d) Health monitoring systems embedded in the form of a computer chip in contact lenses will help.com plan our diet and treatment plan based on the parameters like blood sugar level, intraocular pressure [24].
e) The use of LCD crystals in the bulk of a silicone hydrogel lens can help.com to use virtual projection; digital screens in the near future will aim for [23].
f) In Contact lens materials, even though the penetration of silicone hydrogels in the current market is low, majority of the market share will shift using this material due to its break thought the invention of improved oxygen permeability, it can retain their share well in the markets in the future [17,23].
g) Improvements like anti bacterial coating on contact lenses are giving promising results which can help use them for extended wear without any worry of infections. Possibilities for making a Photo chromatic contact lenses are explored and will be achieved soon [25-29].
Modality
Silicone hydrogels will take the majority of the market and will exist even in future. Mostly the contact lenses have a freedom to wear and remove easily whenever we want and where ever you want [30-34].
Conclusion
Contact lenses have an exponential growth in material development, design and production in the last two decades.Newer technologies in the coming years can help.com make a more productive, versatile, comfortable and safer wearing lenses for the coming generations ahead [35-39].
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Growth of Cellulose Acetate Butyrate Market Analysis and Forecasts to 2021
Growth of Cellulose Acetate Butyrate Market Analysis and Forecasts to 2021
MarketResearchNest.com adds “Global Cellulose Acetate Butyrate Market 2017-2021” new report to its research database. The report spread across 72 pages with table and figures in it.
Research analysts forecast the global cellulose acetate butyrate market to grow at a CAGR of 4.28% during the period 2017-2021.
About Cellulose Acetate Butyrate
Cellulose acetate butyrate is a thermoplastic…
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#Cellulose Acetate Butyrate#Cellulose Acetate Butyrate Analysis#Cellulose Acetate Butyrate Growth#Cellulose Acetate Butyrate Industry#Cellulose Acetate Butyrate Industry Trends#Cellulose Acetate Butyrate Market#Cellulose Acetate Butyrate Share#Cellulose Acetate Butyrate Size#Cellulose Acetate Butyrate Trends
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Cellulose Acetate Butyrate Market Size Worth $997.8 Million By 2025
The global cellulose acetate butyrate market is anticipated to reach USD 997.8 million by 2025, driven by the growing consumer demand for paints & coatings, lacquers, and printing inks. Increasing construction activities and growing automobile production are expected to bolster the growth of the market further.
Paints & coatings made with cellulose acetate butyrate are used in various applications including automotive plastics, leather, plastic, wood, aviation, medical & healthcare, and architecture. The global CAB market for paints & coatings market is expected to reach USD 532 million by 2025.
Increasing infrastructure spending coupled with increasing automobile production in Asia Pacific is projected to drive the demand for paints & coatings, which in turn is expected to influence the demand for CAB positively. The market is anticipated to grow at a volume CAGR of 3.8% over the next eight years.
Printing inks are expected to be another lucrative segment for the CAB market, with the introduction and implementation of mandatory labelling regulations by various regulatory authorities including FDA. Reducing the weight of a packaging coupled with stringent regulations to print all the information regarding the packed product is expected to augment the demand for printing inks that are not affected by external environment conditions. The segment is expected to grow at a volume CAGR of 3.2% over the projected period.
Browse Details of Report @ https://www.hexaresearch.com/research-report/cellulose-acetate-butyrate-cab-market
Some of the key players in the market with a global presence include Eastman, Mitsubishi Rayon and Diacel and Celanese. Other vendors in the market include Xiamen Hisunny Chemical Co., Ltd., Chemos GmbH & Co. KG, Haihang Industry Corporation, and Simagchem Corporation. With the relative growth in demand from the end-use markets such as paints and coatings, lacquers, and printing inks, the market is expected to witness an upward move over the forecast period.
Technology advancement along with expansion in capacity and development in R&D facility is expected to be a key trend in the CAB market over the coming years. Companies are focusing on developing the product with properties such as increased hardness, durability, low moisture absorption and high impact strength. Product innovation is anticipated to result in increasing the application scope of the product, thereby, propelling its growth over the next few years.
Hexa Research has segmented the global cellulose acetate butyrate (CAB) market on the basis of application and region:
Segmentation by application, 2014 – 2025 (Tons) (USD Million)
• Printing inks
• Paints & Coatings
• Lacquers
• Others
Segmentation by region, 2014 – 2025 (Tons) (USD Million)
• North America
• U.S.
• Europe
• Germany
• U.K.
• Asia Pacific
• China
• Japan
• Central and South America
• Middle East and Africa
Key players analyzed:
• Eastman Chemical
• Mistubishi Rayon
• Diacel
• Celanese
• Xiamen Hisunny Chemical Co., Ltd
• Chemos GmbH & Co.KG
• Haihang Industry Corporation
• Simagchem Corporation
• Rotuba Extruders, Inc.
• Nantong Acetate Fiber Co., Ltd
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About Us: Hexa Research is a market research and consulting organization, offering industry reports, custom research and consulting services to a host of key industries across the globe. We offer comprehensive business intelligence in the form of industry reports which help our clients obtain clarity about their business environment and enable them to undertake strategic growth initiatives.
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Carboxymethyl Cellulose Market Analysis, 2021-2031
Carboxymethyl Cellulose Market: Introduction
Transparency Market Research delivers key insights on the global carboxymethyl cellulose market. In terms of revenue, the global carboxymethyl cellulose market is estimated to expand at a CAGR of 3.6% during the forecast period, owing to numerous factors, regarding which TMR offers thorough insights and forecast in its report on the global carboxymethyl cellulose market.
The global carboxymethyl cellulose market is broadly affected by several factors, including expansion of the global food & beverage industry. Characteristics of carboxymethyl cellulose such as thickening ability, rheology modification, water retention, filtration reduction, and binding ability are expected to drive the demand for carboxymethyl cellulose in the near future.
Carboxymethyl Cellulose Market: Dynamics
Carboxymethyl cellulose is extensively employed in the manufacture of baked goods, ice creams, dairy products, gels in heart & cornea surgeries, coating of tablets, finishing of fabric, film forming agent in lotion, creams, shampoos, drilling fluid, etc. It is utilized extensively in food & beverage and pharmaceutical sectors.
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Characteristics of carboxymethyl cellulose to control crystallization and reduce crystal size help retain the effectiveness of frozen food. Carboxymethyl cellulose helps avoid the formation of sandy texture in half-frozen products such as milk shakes and fruit punches. In cosmetics and pharmaceutical sectors, high purity grade of carboxymethyl cellulose is employed as a fat-free ointment base or tablet filling matrix.
Mixed esters of carboxymethyl cellulose, such as carboxymethyl cellulose acetate butyrate, exhibit zero-order release of the active component when used as a filling matrix for drug-delivery agents.
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The increase in demand for hydrocolloids in foodstuffs, owing to the rapid expansion of convenience food & beverages sector is likely to drive the demand for carboxymethyl cellulose in the near future. Some consumers are allergic to gluten.
This makes them intolerant to conventional gluten-containing desserts such as low-fat ice creams, non-fat ice creams, frozen novelties, and frozen yogurt. Carboxymethyl cellulose acts as a thickener and stabilizer in ice creams and other frozen desserts.
This helps maintain the texture and appearance of desserts. Furthermore, carboxymethyl cellulose is available at lower cost than other thickeners and stabilizers. These factors are estimated to propel the demand for carboxymethyl cellulose in the food & beverages segment in the near future.
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Carboxymethyl Cellulose Market: Prominent Regions
Based on region, the global carboxymethyl cellulose market has been segmented into North America, Asia Pacific, Europe, Latin America, and Middle East & Africa. Asia Pacific dominated the global carboxymethyl cellulose market in 2020. The region is expected to maintain its dominance during the forecast period. Countries with large population and high growth in middle-class population, such as China and India, offer lucrative opportunities to the market in Asia Pacific. Sales of packaged food are rising in India, owing to an increase in disposable income of consumers.
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Asia Pacific is a prominent market for fast food, with significantly large markets in China, Japan, and India. The presence of large numbers of consumers of fast food in the region is driving the carboxymethyl cellulose market in Asia Pacific. Furthermore, rise in investments in pharmaceutical and cosmetics sectors by key manufacturers in the region is boosting these industries in Asia Pacific. The expansion of pharmaceutical and cosmetics industries is projected to offer lucrative opportunities to the carboxymethyl cellulose market in the region.
Carboxymethyl Cellulose Market: Key Players
Key players operating in the global carboxymethyl cellulose market are Nouryon Chemicals Holding B.V., DuPont de Nemours, Inc., CP Kelco, Ashland Inc., Jining Fortune Biotech Co., Ltd., Nippon Paper Industries Co., Ltd., Daicel Corporation, Dai-Ichi Kogyo Seiyaku Co., Ltd, and Quimica Amtex S.A De C.V.
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Cellulose-Based Plastics Market Overview Highlighting Major Drivers, Size, Share, and Demand Report 2021- 2028
Cellulose-based plastics are used to produce cellophane, thermoplastic products, ophthalmic goods, toys, and sheets, among others. Increase in implementation of stringent regulations regarding use of conventional plastics due to environmental concerns and ban on use of various plastics has created rising demand for cellulose-based plastics that are produced from renewable raw materials. Cellulose-based plastics are also biodegradable, which is another factor driving market revenue growth.
The report offers an insightful depiction of the value chain and the distribution channels of the global market, alongside identifying an array of business strategies employed by industry professionals. With a special focus on market scope and application areas, the report covers numerous industry aspects, including the current industry trends, growth potential, up-to-date outlines, and market restraints, among others.
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Key Market Competitors
The global Cellulose-Based Plastics industry is widely fragmented due to the presence of numerous competitors across several regional and local segments of the market. These players are said to dominate the industry in terms of their strong geographical reach and a large number of production facilities. The companies operating in this market are in high competition with one another in terms of technological capabilities, product development and innovation, and product pricing strategies.
Leading Market Players Profiled in the Report:
Celanese Corporation, Solvay, Daicel Chemical Industries, Mitsubishi Rayon Company Limited, Eastman Chemical Company, SK Chemicals Co. Ltd., Rayonier Advanced Materials, Sappi, Merck Millipore, and Haihang Industry.
The report categorizes the market into different key segments based on types and applications, along with key regional segmentation. The report offers insights into the segment expected to garner traction during the forecast period, and the region expected to dominate the market in the coming years.
Type Outlook (Revenue, USD Million; 2018–2028)
Cellulose Butyrate
Cellulose Acetate
Cellulose Propionate
Others
Application Outlook (Revenue, USD Million; 2018–2028)
Thermoplastic
Extruded Films
Rods
Sheets
Ophthalmic Goods
Others (Toys, Sport Goods)
End-use Outlook (Revenue, USD Million; 2018–2028)
Food Packaging
Automotive
Electronics
Building/Construction
Agriculture
Sports & Leisure
Consumer Goods
Regions Covered in This Report:
North America(U.S., Mexico, and Canada)
Asia Pacific(China, Japan, India, and Rest of Asia Pacific)
Europe(U.K., Germany, France, and Rest of Europe)
Latin America(Brazil and Rest of Latin America)
Middle East & Africa(GCC Countries and Rest of Middle East & Africa)
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Key Factors influencing market remuneration:
The global Cellulose-Based Plastics market report includes a detailed study of the product spectrum of the market and further describes the different product types, including One-sided, Two-sided, and Others.
The report zeroes in on the overall market dynamics and presents information with regard to the producers and distributors, manufacturing cost structure, and downstream buyers.
Details pertaining to the expected growth rate, industry share, revenue accumulated, and product segmentation are depicted in this report.
The application landscape of the global Cellulose-Based Plastics market can be categorized into For Human, For Animals, and Others.
The study further examines the industry share and product demand of each application, coupled with the predicted growth patterns of the various application segments.
Other vital factors, such as market concentration ratio and raw material processing rate, have also been covered under the latest study.
Highlights of the Table of Contents:
Report Overview 1.1 Research Scope 1.2 Key Cellulose-Based Plastics market segments 1.3 Major players 1.4 Market analysis by product type 1.5 Market analysis by application 1.6 Report timeline
Global Growth Trends 2.1 Global Cellulose-Based Plastics market size 2.2 Latest trends of the Cellulose-Based Plastics market by region 2.3 Key growth trends
Competitive Outlook 3.1 Global Cellulose-Based Plastics market key players 3.2 Global Cellulose-Based Plastics size by manufacturers 3.3 Products of major players 3.4 Entry barriers in the Cellulose-Based Plastics market 3.5 Mergers, acquisitions, joint ventures, and strategic alliances
Cellulose-Based Plastics Market by product type
4.1 Global Cellulose-Based Plastics Sales by Product
4.2 Global Cellulose-Based Plastics by Product Revenue
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What is the use of n-butyl acetate?
As a chemical raw material, what are the applications of n-butyl acetate in industrial use?
N-Butyl Acetate application:
1. Used in collodion, nitrocellulose, varnish, artificial leather, medicine, plastics and perfume industries. It is an excellent organic solvent that can dissolve rosin, polyvinyl acetate, polyacrylate, polyvinyl chloride, chlorinated rubber , Eucommia gum, polymethyl methacrylate, etc.
2. Used as analytical reagents, chromatographic analysis standard materials and solvents
3. It is an excellent organic solvent, widely used in nitrocellulose varnish, used as a solvent in the processing of artificial leather, fabrics and plastics, and also used in the perfume industry
4. GB 2760-96 stipulates that it is permitted to use edible spices. As a spice, it is widely used in the preparation of banana, pear, pineapple, apricot, peach, strawberry, and berry flavors. It can also be used as a solvent for natural rubber and synthetic resin.
5. Occasionally used in fruit-flavored flavors, it is mainly used for its good spreading power, and it is more suitable for use as a top fragrance, but the amount should be small, so as not to stand out alone and affect the effect. It can be widely used in edible flavors such as apricots, bananas, peaches, pears, pineapples, raspberries, and strawberries.
6. Excellent organic solvent, good for cellulose acetate butyrate, ethyl cellulose, chlorinated rubber, polystyrene, methacrylic resin and many natural resins such as tannin extract, manila gum, damar resin, etc. Solubility. Widely used in nitrocellulose varnish, used as a solvent in the processing of artificial leather, fabrics and plastics, used as an extractant in various petroleum processing and pharmaceutical processes, and also used in spice compounding and apricot, banana, pear, pineapple, etc. The ingredients of various fragrances.
7. Commonly used organic solvents, verification of thallium, tin and tungsten, determination of molybdenum and rhenium, antibiotic extractant.
BCC-N-Butyl Acetate supplier. Have a scientific production process and a large-scale production base. The N-Butyl Acetate produced is cheap and of good quality.
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N-Propyl Acetate – A key Commodity for Various Chemical Industries
N-PROPYL ACETATE
N-Propyl Acetate is a chemical compound also known as Propyl Ester, 1-Propyl Acetate, Propyl Ethanoate, 1-acetoxypropane, formed by the esterification of acetic acid and n-propanol. It is a volatile, colorless, highly flammable, toxic liquid with a fruity aroma. Propyl Acetate is miscible with most of the organic solvents and is also an active solvent for nitrocellulose, cellulose acetate butyrate, polyester, alkyd, and acrylic resins, but it is only sparsely soluble in water. Owing to these properties of n-Propyl Acetate, it has wide applications as a solvent in various industries including printing, paints, coatings, automotive, pharmaceuticals, chemicals, food and beverages, cosmetics and fragrances.
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N-Propyl Acetate comes in different grades including reagent and technical grade, agricultural and pharmaceutical grade, and optical grade. The N-Propyl Acetate market is bifurcated into Purity≥99.5% and Purity≥ 99.0%. The purity≥ 99.0% segment owns the leading market share of Propyl Acetate.
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APPLICATIONS OF N-PROPYL ACETATE:
Paints & Coatings: Due to its strong ability to dissolve organic and synthetic solvents and its tendency to thin other solvents, it is used in the manufacturing of Paints and Coatings.
Wood lacquers: It has the capacity to dissolve a wide range of resins (e.g., cellulose nitrate, acrylates, alkyd resin), which also makes it extremely suitable as a solvent for wood lacquers and industrial finishes.
Pharmaceuticals: It is used as an intermediate in the production of pharmaceutical compounds. It also acts as a germicide and is therefore used in sanitizers and disinfectants along with ethanol.
Cosmetic / personal care solvent: Alkyl acetates are usually used as cosmetic ingredients, with a wide range of functions as fragrances, solvents, or skin-conditioning agents, depending on the specific ingredient.
Fragrance solvent: It is also used as a solvent in perfumes and is found as an ingredient in aerosol sprays.
Food and Beverages: It is also used as a flavoring additive because of its fruity odor, which is like pears.
Printing inks: It is used as a solvent in printing inks mainly for flexographic and screen-printing inks which are prominently used in printing postcards, magazines, and cardboard containers.
N-PROPYL ACETATE HANDLING AND STORING
Propyl Acetate should be handled with proper care and attention. Protective gear such as goggles, water-resistant gloves and attire should be worn to avoid contact with skin and eyes. There must be an implementation of sufficient natural or exhaust ventilation coupled with proper respiratory protection to avoid the exposure of vapors.
It must be stored in a tightly closed container, away from direct sunlight or heat, in a well-ventilated space. Opened container should be resealed and stored properly to avoid any kind of leakage as this is a highly inflammable gas with toxic vapors.
HAZARD AND SAFETY
According to the National Fire Protection Association, the health rating and fire rating of N- Propyl Acetate is 1 & 3, respectively. It indicates that upon prolonged exposures, it can cause irritation as well as inhalation of its vapors is also toxic. Moreover, Propyl Acetate is highly flammable and can easily catch fire by heat or sparks under environmental conditions. It is harmful if swallowed.
If exposed for long duration there can be potential health effects like, skin and eyes irritation coupled with pain and redness in eyes.
First Aid If Exposed:
For Eyes: Rinse with plenty of water till gets better. Refer to doctor if irritation persists
For Skin: Wash the affected area with water and soap. Refer to doctor if irritation persists
Inhalation: Fresh Air and Take Rest
Ingestion: Consult Doctor
N-PROPYL ACETATE MARKET:
The major share of global demand for n-propyl acetate is held by the Asia Pacific region, because of increasing construction, rapid growth, and strong establishment of industries such as chemicals, printing ink, and food & beverages in the region, especially in China and India. N-propyl market finds a significant place in the market due to its high demand in industries involved in paints, coatings, and printing inks. Moreover, the cosmetic and food and beverage industry is witnessing exponential growth over the past decade. This exponential growth has driven the global propyl acetate market as manufacturers are progressively utilizing this chemical in the production of their products such as perfumes, deodorants, etc. and utilizing it as a flavoring agent.
North America and Europe are prominent regions for the Propyl Acetate market as both these advanced regional markets collectively account for approximately half of the total demand because of the presence of the leading chemical industries in the regions. Moreover, a significant growth in the Propyl Acetate market has been shown by Middle East Asia in the past few years and is likely to witness potential growth in the forecast period.
EFFECT OF COVID-19 PANDEMIC
Due to the impact of the COVID-19 pandemic, the decline in the demand for N-Propyl Acetate was witnessed among other chemicals owing to nationwide lockdowns and subsequent disruptions in supply chains. However, overall decent growth has been observed in its demand since the industries got operational after the lockdowns. Additionally, surging demand for advanced coating material in the automotive industry is expected to accelerate the market for N- Propyl Acetate in the forthcoming years.
LEADING PLAYERS:
BASF Group, Du Pont Inc., DOW, Eastman Chemical Company, Solvay S.A., Showa Denko K.K., Sankyo Chem., Daicel Co., Sasol corporation, Shiny Chemical industrial Co. ltd., Zibo Nuoao Chem. Co. Ltd., Wujiang Shuguang Chemical CO. Ltd., Ningbo Yongshun and Tosoh corporation are some leading players in the N-Propyl Acetate market.
CONCLUSION:
Propyl Acetate Market is expanding at a faster pace with considerable growth rates over the past few years and to grow significantly in the coming years owing to the increasing demand for N-Propyl Acetate as a solvent or an intermediate from various end use industries such as Chemicals, Paints, Automotive, Pharmaceuticals, Cosmetics, Food & Beverages and Others. Moreover, the expansion of capacity of the N-Propyl Acetate plant by Showa Denko (SDK), Tokyo has increased the production of N-Propyl Acetate. It is used in solvents for ink for special gravure printing which is extensively utilized for exterior packaging films for confectionary are likely to create opportunities in the n-propyl acetate market in the upcoming years.
FAQs:
Which are the different grades of N-Propyl Acetate?
The different grades of N- Propyl Acetate are Reagent and Technical Grade, Agricultural and Pharmaceutical Grade, and Optical Grade.
Which are the major applications for N-Propyl Acetate?
The major applications for N-Propyl Acetate include Paints, Coatings and Printing inks.
Who are the key players in the Global N-Propyl Acetate market?
BASF Group, Eastman Chemical Company, Du Pont Inc., DOW, Solvay S.A., Showa Denko K.K., Sankyo Chem., Daicel Corporation, Sasol corporation, Shiny Chemical industrial Co. ltd., Zibo Nuoao Chem. Co. Ltd., Wujiang Shuguang Chemical CO. Ltd., Ningbo Yongshun and Tosoh corporation are some leading players in the N-Propyl Acetate market.
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Qualitative Analysis of Cellulose Esters Market 2021-2025
The global Cellulose Esters Market report is a compilation of first-hand information, qualitative and quantitative evaluation by industry analysts, inputs from industry experts and industry participants across the value chain.
The global Cellulose Esters Industry report provides an extensive analysis of macro-economic indicators, parent market trends, and governing factors along with market attractiveness as per segments. —————————————————————————————————————————————————— Sample Copy of This Report with Full TOC @ https://www.alexareports.com/report-sample/2528110 —————————————————————————————————————————————————— All manufactures in the world are committed to the improvement of product. These two years, some of manufactures can almost catch up with the world’s leading technology too. Most technologies are developed by the manufacturers instead of importing from other companies.
Important Manufactures in this report are Solvay, Mitsubishi Chemical Holdings Corporation, Eastman Chemical Company, China National Tobacco Corporation, Daicel Corporation, Celanese Corporation, Acordis Cellulostic Fibers, Sappi, Rayonier Advanced Materials, Sichuan Push Acetati,
Global Cellulose Esters Market: Product Segment Analysis
Cellulose Acetate Cellulose Acetate Butyrate Cellulose Acetate Propionate Cellulose Nitrate
Global Cellulose Esters Market: Application Segment Analysis
Coatings Plasticizers Cigarette Filters Films & Tapes Inks
Global Cellulose Esters Market Report 2021 presents an in-depth assessment of the Cellulose Esters including enabling technologies, key trends, market drivers, challenges, standardization, regulatory landscape, deployment models, operator case studies, opportunities, future roadmap, value chain, ecosystem player profiles and strategies. The report also presents forecasts for Cellulose Esters investments from 2021 till 2027. It provides a comprehensive overview of the market, its dynamics, structure, characteristics, main players, growth and demand drivers, etc.
Cellulose Esters Market Report give depth study of current situation of the industry. Cellulose Esters Manufacturers are valuable source of guidance and direction for companies and individuals interested in the Industry.
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The global cellulose acetate butyrate market size is projected at USD 940 million by 2025, according to Adroit Market Research. The company launched a research study titled, “Global Cellulose Acetate Butyrate (CAB) Market Size 2017, By Application (Paints & Coatings, Lacquers, Printing Inks, Others), By Region and Forecast 2018 to 2025”.
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Carboxymethyl Cellulose Market is estimated to expand at a CAGR of 3.6% by 2031
Carboxymethyl Cellulose Market: Introduction
Transparency Market Research delivers key insights on the global carboxymethyl cellulose market. In terms of revenue, the global carboxymethyl cellulose market is estimated to expand at a CAGR of 3.6% during the forecast period, owing to numerous factors, regarding which TMR offers thorough insights and forecast in its report on the global carboxymethyl cellulose market.
The global carboxymethyl cellulose market is broadly affected by several factors, including expansion of the global food & beverage industry. Characteristics of carboxymethyl cellulose such as thickening ability, rheology modification, water retention, filtration reduction, and binding ability are expected to drive the demand for carboxymethyl cellulose in the near future.
Carboxymethyl Cellulose Market: Dynamics
Carboxymethyl cellulose is extensively employed in the manufacture of baked goods, ice creams, dairy products, gels in heart & cornea surgeries, coating of tablets, finishing of fabric, film forming agent in lotion, creams, shampoos, drilling fluid, etc. It is utilized extensively in food & beverage and pharmaceutical sectors.
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Characteristics of carboxymethyl cellulose to control crystallization and reduce crystal size help retain the effectiveness of frozen food. Carboxymethyl cellulose helps avoid the formation of sandy texture in half-frozen products such as milk shakes and fruit punches. In cosmetics and pharmaceutical sectors, high purity grade of carboxymethyl cellulose is employed as a fat-free ointment base or tablet filling matrix.
Mixed esters of carboxymethyl cellulose, such as carboxymethyl cellulose acetate butyrate, exhibit zero-order release of the active component when used as a filling matrix for drug-delivery agents.
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The increase in demand for hydrocolloids in foodstuffs, owing to the rapid expansion of convenience food & beverages sector is likely to drive the demand for carboxymethyl cellulose in the near future. Some consumers are allergic to gluten.
This makes them intolerant to conventional gluten-containing desserts such as low-fat ice creams, non-fat ice creams, frozen novelties, and frozen yogurt. Carboxymethyl cellulose acts as a thickener and stabilizer in ice creams and other frozen desserts.
This helps maintain the texture and appearance of desserts. Furthermore, carboxymethyl cellulose is available at lower cost than other thickeners and stabilizers. These factors are estimated to propel the demand for carboxymethyl cellulose in the food & beverages segment in the near future.
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Carboxymethyl Cellulose Market: Prominent Regions
Based on region, the global carboxymethyl cellulose market has been segmented into North America, Asia Pacific, Europe, Latin America, and Middle East & Africa. Asia Pacific dominated the global carboxymethyl cellulose market in 2020. The region is expected to maintain its dominance during the forecast period. Countries with large population and high growth in middle-class population, such as China and India, offer lucrative opportunities to the market in Asia Pacific. Sales of packaged food are rising in India, owing to an increase in disposable income of consumers.
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Asia Pacific is a prominent market for fast food, with significantly large markets in China, Japan, and India. The presence of large numbers of consumers of fast food in the region is driving the carboxymethyl cellulose market in Asia Pacific. Furthermore, rise in investments in pharmaceutical and cosmetics sectors by key manufacturers in the region is boosting these industries in Asia Pacific. The expansion of pharmaceutical and cosmetics industries is projected to offer lucrative opportunities to the carboxymethyl cellulose market in the region.
Carboxymethyl Cellulose Market: Key Players
Key players operating in the global carboxymethyl cellulose market are Nouryon Chemicals Holding B.V., DuPont de Nemours, Inc., CP Kelco, Ashland Inc., Jining Fortune Biotech Co., Ltd., Nippon Paper Industries Co., Ltd., Daicel Corporation, Dai-Ichi Kogyo Seiyaku Co., Ltd, and Quimica Amtex S.A De C.V.
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Cellulose-Based Plastics Market Share, Industry Growth, Trend, Drivers, Challenges, Key Companies by 2027
The global cellulose-based plastics market size is expected to reach USD 176.5 Million at a steady CAGR of 17.5% in 2028, according to latest analysis by Emergen Research. Global cellulose-based plastics market revenue growth is driven by rising demand for cellulose acetate in electronics and food packaging applications, and the trend is expected to continue over the forecast period.
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The report also offers extensive details about the leading companies involved in the market along with their profiles, product portfolio, production and manufacturing capacity, cost analysis, market reach, and financial standings. It also pays special attention to strategic initiatives taken by the companies to gain a robust footing in the market like mergers and acquisitions, joint ventures, product developments, technological advancements, brand promotions and product launches, and partnerships, among others.
Leading Players of the Cellulose-Based Plastics Market Profiled in the Report are:
Celanese Corporation, Solvay, Daicel Chemical Industries, Mitsubishi Rayon Company Limited, Eastman Chemical Company, SK Chemicals Co. Ltd., Rayonier Advanced Materials, Sappi, Merck Millipore, and Haihang Industry.
Emergen Research has segmented the global cellulose-based plastics market on the basis of type, application, end-use, and region:
Type Outlook (Revenue, USD Million; 2018–2028)
Cellulose Butyrate
Cellulose Acetate
Cellulose Propionate
Others
Application Outlook (Revenue, USD Million; 2018–2028)
Thermoplastic
Extruded Films
Rods
Sheets
Ophthalmic Goods
Others (Toys, Sport Goods)
End-use Outlook (Revenue, USD Million; 2018–2028)
Food Packaging
Automotive
Electronics
Building/Construction
Agriculture
Sports & Leisure
Consumer Goods
Regional Fragmentation:
North America
Europe
Asia Pacific
Latin America
Middle East & Africa
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The report offers a panoramic view of the Cellulose-Based Plastics market on both global and regional levels. The study is further supported by key statistical data and industry-verified facts. The study strives to carefully gauge the present and future market growth prospects, untapped avenues, demand and consumption patterns, and the crucial factors poised to impact each market region’s revenue potential. Therefore, the report scrutinizes the numerous growth trends & prospects and the significant challenges and threats that the market players might face in the upcoming years.
Target Audience of the Global Cellulose-Based Plastics Market report:
Global Cellulose-Based Plastics market providers, traders, distributors, and suppliers
Research organizations, End-use industries, consulting organizations, and various alliances related to this business sphere.
Independent regulatory authorities, government bodies, and policymakers.
Highlights of the Table of Contents:
Report Overview 1.1 Research Scope 1.2 Key Cellulose-Based Plastics market segments 1.3 Major players 1.4 Market analysis by product type 1.5 Market analysis by application 1.6 Report timeline
Global Growth Trends 2.1 Global Cellulose-Based Plastics market size 2.2 Latest trends of the Cellulose-Based Plastics market by region 2.3 Key growth trends
Competitive Outlook 3.1 Global Cellulose-Based Plastics market key players 3.2 Global Cellulose-Based Plastics size by manufacturers 3.3 Products of major players 3.4 Entry barriers in the Cellulose-Based Plastics market 3.5 Mergers, acquisitions, joint ventures, and strategic alliances
Cellulose-Based Plastics Market by product type
4.1 Global Cellulose-Based Plastics Sales by Product
4.2 Global Cellulose-Based Plastics by Product Revenue
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Agricultural Films Market@ https://www.emergenresearch.com/industry-report/agricultural-films-market
Nanopatterning Market@ https://www.emergenresearch.com/industry-report/nanopatterning-market
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What is the use of n-butyl acetate?
As a chemical raw material, what are the applications of n-butyl acetate in industrial use?
N-Butyl Acetate application:
1. Used in collodion, nitrocellulose, varnish, artificial leather, medicine, plastics and perfume industries. It is an excellent organic solvent that can dissolve rosin, polyvinyl acetate, polyacrylate, polyvinyl chloride, chlorinated rubber , Eucommia gum, polymethyl methacrylate, etc.
2. Used as analytical reagents, chromatographic analysis standard materials and solvents
3. It is an excellent organic solvent, widely used in nitrocellulose varnish, used as a solvent in the processing of artificial leather, fabrics and plastics, and also used in the perfume industry
4. GB 2760-96 stipulates that it is permitted to use edible spices. As a spice, it is widely used in the preparation of banana, pear, pineapple, apricot, peach, strawberry, and berry flavors. It can also be used as a solvent for natural rubber and synthetic resin.
5. Occasionally used in fruit-flavored flavors, it is mainly used for its good spreading power, and it is more suitable for use as a top fragrance, but the amount should be small, so as not to stand out alone and affect the effect. It can be widely used in edible flavors such as apricots, bananas, peaches, pears, pineapples, raspberries, and strawberries.
6. Excellent organic solvent, good for cellulose acetate butyrate, ethyl cellulose, chlorinated rubber, polystyrene, methacrylic resin and many natural resins such as tannin extract, manila gum, damar resin, etc. Solubility. Widely used in nitrocellulose varnish, used as a solvent in the processing of artificial leather, fabrics and plastics, used as an extractant in various petroleum processing and pharmaceutical processes, and also used in spice compounding and apricot, banana, pear, pineapple, etc. The ingredients of various fragrances.
7. Commonly used organic solvents, verification of thallium, tin and tungsten, determination of molybdenum and rhenium, antibiotic extractant.
BCC-N-Butyl Acetate supplier. Have a scientific production process and a large-scale production base. The N-Butyl Acetate produced is cheap and of good quality.
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U.S. Esters Market Status, Share And Growth Factors Impact Analysis till 2022
March 03, 2021: U.S. Esters Market is estimated to grow significantly in the forecast period owing to the increase in demand for stabilizers and emulsifiers from personal care segment. Esters are the organic compounds that produce organic or inorganic acids when reacted with water. Esters possess properties like flexibility and low polarity and are more volatile than the equivalent amides. Esters are widely used as aromas in different fruits, pharmaceutical items and personal care products like shampoos.
U.S. esters market is witnessing growth due to factors like developments and innovations in surfactants, lubricants, pesticides and others, economic developments, growing population that demands personal care products and growing industrialization. Esters are extensively used in synthetic lubricants, which ultimately encourages U.S. esters industry. Moreover, growth in food industry due to increasing population is fueling United States esters market. However, the market is restrained by the government regulations for limiting the use of unsafe chemicals in the food & personal care products and unstable prices of raw materials.
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Nevertheless, low labor cost and regulations by government are encouraging the market growth of esters. Functional efficiency followed by biodegradability, sustainability and performance offered by esters are gaining traction by the market players. Also, the development of various personal care industries are expected to bring opportunities in U.S. esters industry in the coming years.
U.S. esters market is categorized on the basis of product type, application and geography. On the basis of product type, the market is divided into complex esters, diesters, monoesters and methyl esters. Complex esters segment is expected to lead U.S. esters industry since they offer high film thickness, wide viscosity range, high surface activity, and are cost-effective.
Based on application, U.S. esters market is bifurcated into industrial lubricants, automotive lubricants, marine lubricants, aviation lubricants and food grade lubricants. Aviation segment followed by automotive and industrial segment are expected to hold larger market share of esters due to wide applications. Geographically, U.S. esters industry is segmented as The West, Southwest, The Middle Atlantic, New England, The South and The Midwest.
The key players in United States esters industry comprise Arkema, Chemtura, Lanxess, Dow Chemical, Evonik Industries, DuPont, Procter & Gamble (P&G), Croda International, Sasol, PCC Chemax, Honeywell, Eastman Chemical, Ashland, AkzoNobel, Innospec, Archer Daniels Midland, LG Chem, Elementis Specialties, Valtris Specialty Chemicals, Rotuba, PMC Biogenix, Polymer Plastics Co. LC.AndStepan Company.
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Market Segment:
U.S. Esters Product Outlook (Volume, Kilo Tons; Revenue, USD Million, 2012 - 2022)
• Fatty esters
• By product
• Glycerol monostearate (GMS)
• By application
• Food additive
• Emulsifier for oil & greases
• Pharmaceuticals
• Personal care & cosmetics
• Others
• Medium Chain Triglycerides (MCTs)
• By application
• Dietary supplements
• Medical supplements
• Others
• Sorbitan esters
• By application
• Personal care & cosmetics
• Food additives
• Paints & pigments
• Pharmaceuticals
• Agricultural films & plastics
• Others
• Ethyl glycol monostearate
• By application
• Personal care & cosmetics
• Others
• Fatty acid methyl ester (FAME)
• By application
• Biodiesel
• Lubricants
• Metalworking fluids
• Polymer, coatings, & plasticizers
• Personal care
• Others
• Phosphate esters
• By application
• Lubricant base stock
• Agrochemicals
• Surfactants
• Flame retardants
• Plasticizers
• Paints & coatings
• Others
• Acrylic esters
• By product
• Methyl acrylate
• By application
• Coatings, adhesives, sealants, and elastomers (CASE)
• Surfactants
• Plastic additives
• Textiles & fibers
• Chemical synthesis
• Others
• Ethyl acrylate
• By application
• Copolymers & homopolymers
• Chemical synthesis
• Paints & coatings
• Others
• Butyl acrylate
• By application
• Personal care & cosmetics
• Paints & coatings
• Others
• 2-Ethylhexyl acrylate
• By application
• Copolymers & homopolymers
• Pressure sensitive adhesives
• Paints & coatings
• Others
• Others
• Cellulose esters
• By product
• Cellulose acetate
• By application
• Film base
• Coating additive
• Synthetic fibers
• Others
• Cellulose acetate propionate (CAP)
• By application
• Printing inks
• Varnishes & coatings
• Textile & apparel
• Plastic processing
• Nail care products
• Others
• Cellulose acetate butyrate (CAB)
• By application
• Coating additive
• Pharmaceuticals
• Textile & apparel
• Plastic processing
• Others
• Allyl & aromatic esters
• By product
• Ethyl acetate
• Ethyl benzoate
• Methyl laurate
• N-butyl stearate (NBS)
• Others
• By application
• Personal care
• Agricultural chemical
• Lubricants
• Pharmaceuticals
• Paints & coatings
• Surfactants & detergents
• Others
• Others
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Lupine Publishers | Contact Lens Materials and Modalities
Lupine Publishers | Trends in Ophthalmology Open Access Journal
Abstract
Introduction: Past two decades have seen a steep rise in the usage of contact lenses and that brought a major revolution in the materials research, design and manufacturing technologies. This also impacted the optometrists thus influencing the patient usage, modalities and duration. The current article briefs the changes in the field of contact lenses and the changing trends.
Methods: Contact lens materials and its manufacturing, wearing modalities and changing trends in prescribing them were identified, reviewed and summarized as per the topic requirements from scientific papers, authentic articles, books and websites to cover the challenges our ancestors have faced and the solutions that were provided in the past were summarized for the reader in an easy accessible way.
Conclusion: Newer generation of contact lens materials made an average contact lens wearer comfortable by wearing lenses for longer hours without discomfort and with minimal complications. Due to the advent of newer lens materials, practitioners have been given more options for choosing a best suited lens based on specific wearer requirements and needs. In this way, newly available materials and designs make the lens wear safer and less prone to complications by shifting the patient from conventional to planned replacement lenses (PRL) and from PRL to daily disposables to ensure a healthy and safer vision.
Keywords: PMMA; Rigid Gas Permeable Lenses; HEMA; Silicone Hydrogels; Extended Wear; Flexible Wear; Daily Disposables; Multifocal Contact Lenses; Aspheric; Toric
Abbreviation: CAB: Cellulose Acetate Butyrate; RGP: Rigid Gas Permeable Lens; P-HEMA: Poly Hydroxy Ethyl Methacrylate; PVP: Poly Vinyl Pyrolidone Introduction
Contact lenses are medical devices commonly used to correct the vision without the need of spectacles. Even though the concept was very old, till 1887, a structure similar to our today's contact lens was not made. A first contact lens like structure was made in 1887 by F. A Muller by blowing glass to make a prosthetic eye. In 1930's a first contact lens made up of glass was used which covers whole the cornea and a small part of sclera was used for vision correction making glass the first contact lens material [1]. In 1937, a material named Poly methyl methacrylate (PMMA) was introduced as a contact lens material which mimics todays' scleral lens of a larger diameter. In 1948, Kevin Tuohy made a contact lens called "Microlens" which covers only cornea with 10 to 12 mm diameter [1,2]. After using PMMA as a contact lens material for some time, hypoxic complications arise due to it’s very poor oxygen permeable nature after use, making.com to explore for newer lens materials. Currently, due to its zero-oxygen permeability, it is used to make diagnostic trial contact lenses instead of actual contact lenses due to its ability to retain the parameters, ease of care and maintenance [3]. Rigid Gas Permeable Lenses (RGP)
Noting the importance of Oxygen permeability, few developments were made to the material to be permeable to oxygen. In the year 1972, Cellulose acetate butyrate (CAB) was proposed as a material to use by Irving Fatt, later in 1978 CAB as a contact lens material got FDA approved. A term (RGP) Rigid gas permeable lens was coined and the lens made with this (CAB) material was manufactured in 1978 in United States [2,4]. In the advent of silicone usage in the medical industry, Siloxane methacrylate material was developed in 1970 by using silicone molecules bonded to methyl methacrylate structures making a contact lens more oxygen permeable [2]. Siloxane acrylates material was patented in 1974 under the name Polycon and was introduced commercially in 1979 which lead the wearing time longer than CAB due to its high oxygen permeability without showing any hypoxic changes in the cornea. However, it was observed that the siloxane acrylate lenses tend to attract more of lipid and less of protein deposits on the lens surface, making the care and regime of newer RGP lens materials different than the previous lens. These deposits lead to lesser lens life than the previous lenses [2].
"Boston" a contact lens material manufacturing company started to develop working towards parameters like oxygen permeability, strength and deposit resistance for improved lens on eye performance since 1972. Elements Fluorine and Carbon were used in specific proportions to synthesize Fluoro-siloxane acrylates and Fluorocarbon acrylates were found effective in controlling the lipid deposits to occur on the lens surface with increased oxygen permeability. These materials still stand good in terms of availability, deposit resistance with good oxygen permeability [5]. Addition of Silicone, Fluorine and Carbon with appropriate amounts made it possible to achieve highest levels of oxygen permeability ever, leading to continuous wear, flexible wear and extended wear modalities possible. During this period in 1987, Fluoro-silicone acrylate material was made available [6]. Due to changing trends in the contact lens market and due to innovations in soft contact lens materials, there is a constant and a sharp decline in the RGP wearers that was observed in the past two decades due to the comfort achieved by soft contact lenses [7]. Silicone Elastomer
In 1956, Silicone elastomer material was developed by Walter Becker which has a highest ever oxygen permeability which is more flexible than RGP lenses, making the contact lens industry to explore newer ways of improvising the lens material in terms of flexibility But, for a product to manufacture out of silicone elastomer was not possible at that time due to its flexible nature, poor wettability and the material adheres to the cornea(suction). Later in 1981 a lens made up of silicone elastomer material was commercialized for correcting children to use as an overnight wear lens due to its exceedingly high oxygen permeability. This material got approved for 30 day continuous wear for non-aphakic prescriptions in 1983 making it the first extended wear lens to be produced [6,8]. Till now these elastomer lenses are available as a mode of correction for aphakia (congenital and acquired) cases mostly in children [9]. The only drawback with these lenses is the brittleness of the material and affinity to attract lipid deposits, making its usage declined in this decade [6,8]. Soft Contact Lens (Hydrogels)
Progress in contact lens materials was extremely rapid and the market equations of using RGP lenses were quickly changed after the development of Poly hydroxy ethyl methacrylate (P-HEMA) as a lens material in 1963 by Otto Wichterle. This material coined a new term called "soft contact lens" due to its soft and flexible nature. The lens made with HEMA was available in 1971 as a commercial product [2,6]. The usage of HEMA as a lens material in the current contact lens market still holds good. After the invention of HEMA as a hydrogel material, the comfort obtained by a wearer lead the path for a term called intermittent contact lens wear, which is not possible with RGP due to the discomfort it caused to an average wearer. However, the water content which is the only source of oxygen transmission through the hydrogel lens was too less when compared to RGP lenses due to their movement and tear exchange. There is a need for a diverse care and regime to be followed to soft contact lens wearers for which different contact lens solutions were devised to clean, rinse, disinfect, and hydrate and to store these lenses.
Due to limitation of water content and oxygen permeability in hydrogel lenses, there were diverse complications that were seen in the soft contact lens users and the users due to the comfort of the lenses, tend to sleep with the lenses on the cornea making the condition more worsen [10]. Observing these diverse ocular changes, few of the traditional RGP practitioners were reluctant to shift their practice and keep on dispensing RGP lenses only [11]. As there is a limitation in increasing the water content that we achieve with hydrogel lenses, scientists started to explore new ways to increase the oxygen passing through the lens which can enable the wearer to achieve better comfort lens with lesser complications [12]. Concept of Disposable soft contact lenses came into the field in 1985-1986 as the increasing complications can be counteracted by discarding the lenses before the deposits on the lens surface become sufficient enough to create problems like discomfort, bulbar conjunctival redness, allergic reactions in the upper tarsal conjunctiva and lack of oxygen supply due to deposits [13]. Gradually, frequent replacement lenses were so frequently replaced due to increasing in water content of the lenses that there is a need for a modality termed Daily disposable lenses in 1994-1995 to ensure maximum comfort and good ocular health with no requirement of care and maintenance which is a boon for existing, new contact lens wear. As the production need to meet the consumer needs a new manufacturing method called cast moulding turned the disposable modality a practically possible reality [2,14].
Even now, majority of the contact lens market share in developing countries is still contributing to Hydrogel lenses where as in developed countries, majority of the population is using silicone hydrogels and daily disposable hydrogel lenses for their visual needs [15-17]. In this stage, Silicone elastomers were more easily available and used in the market as a commercial product leading the materials science experts to turn their vision towards it. This change made them to think and combine the silicone with hydrogel lenses which set a stage for the generation of silicone hydrogels. The first silicone hydrogel lens was marketed in 2002 [2,9]. Silicone Hydrogels
In soft contact lenses the silicone material is incorporated based on the skeletal structures of classical hydrogel materials like HEMA and thereby making it a better lens material by incorporating:
a) OH groups for increasing the bound water content of the lens materials [18]
b) Materials like polyvinyl pyrolidone (PVP) for improving the wettability of the lenses [18]
Due to the innovation of Silicone hydrogel contact lenses, high oxygen transmissibility is made possible, hence by minimizing corneal hypoxia changes that include corneal oedema, Descemet’s membrane folds, microcysts, limbal hyperaemia and neovascularisation [19]. There are a few patient related .difficulties with these new lenses due to increased stiffness than existing hydrogels, hydrophobic nature and more attraction of lipid deposits. So, there is a need for a better and improved materials and designs making them readily acceptable by the patient [9]. In 2010, Custom made silicone hydrogel lenses are made available in the market [20]. In case of Silicone hydrogel lenses, these inventions can be technically classified into three phases in which the lens materials are synthesized by not only decreasing the stiffness of the lens material, but also by increasing the wettability and water content to a desired level for enhancing the comfort level of silicone hydrogel wearer equal to that achieved by a hydrogel contact lens wearer [18,19,21,22]. Developments in Silicone Hydrogel Materials
a) Properties (Table 1)
1. Good Dk
2. Slightly stiffer
3. Deposit prone surface
4. Decreased Wettability
b) Properties (Table 2)
2. Flexible lens material
1. Improved wettability
c) Properties (Table 3)
1. Better Water content
2. Decrease stiffness
3. It is a Breakthrough technology, which redefines the soft contact lens relationship between Dk and water content by having a higher Dk than water content predicts!
Contact lens advancements in the Future
a) Myopia control contact lenses are very soon going to be available in Asian countries where Myopia is more prevalent.
b) Aberrometers values combined with prescription can help customize the correction to a personalized contact lens manufacturing is possible soon [23].
c) A Multifocal design of contact lens which can have an autofocus capability near the pupillary centres of the eyes using fluid dynamics can be manufactured and fitted which can help.com gain complete visual satisfaction to the wearer [23].
d) Health monitoring systems embedded in the form of a computer chip in contact lenses will help.com plan our diet and treatment plan based on the parameters like blood sugar level, intraocular pressure [24].
e) The use of LCD crystals in the bulk of a silicone hydrogel lens can help.com to use virtual projection; digital screens in the near future will aim for [23].
f) In Contact lens materials, even though the penetration of silicone hydrogels in the current market is low, majority of the market share will shift using this material due to its break thought the invention of improved oxygen permeability, it can retain their share well in the markets in the future [17,23].
g) Improvements like anti bacterial coating on contact lenses are giving promising results which can help use them for extended wear without any worry of infections. Possibilities for making a Photo chromatic contact lenses are explored and will be achieved soon [25-29].
Modality
Silicone hydrogels will take the majority of the market and will exist even in future. Mostly the contact lenses have a freedom to wear and remove easily whenever we want and where ever you want [30-34]. Conclusion
Contact lenses have an exponential growth in material development, design and production in the last two decades.Newer technologies in the coming years can help.com make a more productive, versatile, comfortable and safer wearing lenses for the coming generations ahead [35-39]
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BUTYRIC ACID MARKET ANALYSIS
Butyric Acid Market - Size, Share, Trends, and Forecast 2019 - 2027
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The global butyric acid market size is projected to surpass US$ 125 million by 2027, and register a CAGR of 14.4% over the forecast period (2019 - 2027).
Market Overview
Butyric acid, also known by the chemical names butanoic acid and n-Butyric acid, is a carboxylic acid that is commonly found in its esterified form in plant oils and animal fat. Butyric acid is a colourless liquid with an unpleasant, penetrant odour. It tastes like butter and is used as a flavouring agent in food manufacturing. Butyric acid is soluble in water, ether, and ethanol. It is highly corrosive to metals and tissue, and protective eye-goggles, gloves made of PVC or rubber, as well as chemical-resistant shoes are worn when handling butyric acid as a safety measure. For industrial applications, butyric acid is generally prepared by fermenting starch or sugar.
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Market Dynamics
Butyric acid has several industrial applications, and recently, in the light of increasing petroleum prices and rising need for clean energy resources, butyric acid is being considered as a precursor to biofuels. Butyric acid may emerge as an effective alternative for gasoline in the near future. It has a wide demand in the transportation sector, owing to the variety of advantages butyric acid has over ethanol. For instance, butanol is far less volatile compared to ethanol, does not attract water which makes it ideal for transportation in pipelines, and is also less sensitive to low temperatures. Moreover, butyric acid has uses in the chemical and pharmaceutical industries since it has been associated with several anticancer properties. Several research institutes are engaged in the development of prodrugs containing butyric acid which can be used as a potential treatment of cancers, leukemia, and side effects of alopecia caused by chemotherapy. In the chemical industry, butyric acid has primary application in the manufacture of cellulose acetate butyrate plastics. In end use industries such as cosmetics, and food and beverages, butyric acid esters are used to add fragrance and flavor to products. These factors are expected to drive demand for butyric acid over the forecast period.
However, environmental and health concerns associated with the handling of butyric acid are projected to restrain growth of the global butyric acid market. Inhaling butyric acid can cause coughing, soreness of the throat, and respiratory problems. Furthermore, ingesting butyric acid can result in abdominal pain, and collapse. Physical contact with butyric acid causes skin irritation, burns, blistering, and prolonged exposure can impair the vision.
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Market Outlook
Asia Pacific is expected to emerge as the largest market for butyric acid owing to the rapidly expanding pharmaceutical and agriculture sectors, where butyric acid animal feed application. Agro-based economies such as India are estimated to account for a significant market share during the forecast period. Additionally, presence of several key players in the region coupled with rapidly expanding end use industries is expected to facilitate growth of the Asia Pacific butyric acid market. Stringent regulations by environmental agencies in North America and Europe regarding the use of antibiotics in animal feed will facilitate demand for butyric acid in biofuel production in the regions.
Key Players
Some of the major companies operating in the global butyric acid market are Eastman Chemical Company, Dmitrievsky Chemical Plant, and Alfa Aesar GmbH & CO KG among others.
Key Developments:
30 May 2017, Oxea, the global chemical company successfully stated its carboxylic acids production facility in Oberhausen, Germany. As a result, Oxea enhanced the production output of short-chain fatty acids (SCFAs), such as propionic acid, butyric acid and isobutyric acid.
24 Jan 2013, Eastman Chemical Company announced today expansion of butyric acid production capacity at its Kingsport, Tennessee, facility.
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