#CHINESE MEDICINE for ENDOMETRIOSIS TORONTO
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Enhancing Your Health Naturally: Discover Top Wellness Services in the Greater Toronto Area
The quest for optimal health and wellness often leads individuals to explore various therapeutic avenues. For those residing in the Greater Toronto Area, including Mississauga and Oakville, there are several cutting-edge health services available. Whether you're seeking the expertise of a naturopathic doctor, fertility acupuncture, or advanced therapies like glutathione IV treatment, the region boasts a variety of top-tier options.
Naturopathic Doctor in Mississauga: Personalized Holistic Care
Naturopathic medicine is increasingly recognized for its comprehensive approach to health. A naturopathic doctor in Mississauga offers individualized treatment plans that address the root cause of health issues rather than just alleviating symptoms. These practitioners utilize a blend of natural therapies, including herbal medicine, nutritional counseling, and lifestyle modifications.
Patients often seek naturopathic care for chronic conditions such as digestive disorders, hormonal imbalances, and autoimmune diseases. By emphasizing prevention and self-care, naturopathic doctors help patients achieve long-term health improvements. Moreover, their holistic approach often includes stress management techniques and detoxification processes, which are crucial in today’s fast-paced world.
Fertility Acupuncture Clinic in Oakville: Enhancing Reproductive Health
For couples facing challenges with fertility, acupuncture has emerged as a supportive treatment that complements conventional medical interventions. A fertility acupuncture clinic in Oakville provides specialized services aimed at improving reproductive health for both men and women.
Acupuncture enhances fertility by regulating hormonal balance, improving blood flow to reproductive organs, and reducing stress, which can significantly impact conception. Many studies suggest that acupuncture, when used in conjunction with in-vitro fertilization (IVF), can increase the success rates of pregnancy. Clinics in Oakville offer a serene environment where patients can benefit from this ancient Chinese practice under the guidance of experienced practitioners.
The holistic nature of fertility acupuncture also involves addressing underlying health issues such as polycystic ovary syndrome (PCOS), endometriosis, and sperm quality concerns. By adopting a comprehensive approach, these clinics not only support immediate reproductive goals but also promote overall well-being.
Glutathione IV Therapy in Oakville: The Ultimate Antioxidant Boost
In the realm of advanced wellness therapies, glutathione IV therapy in Oakville stands out as a powerful treatment for enhancing the body’s natural detoxification processes. Glutathione is a potent antioxidant that plays a critical role in neutralizing free radicals, supporting immune function, and detoxifying the liver.
Administered intravenously, glutathione therapy ensures maximum absorption and immediate availability to the body’s cells. This method is particularly beneficial for individuals dealing with chronic illnesses, those recovering from heavy metal exposure, or anyone seeking to boost their overall vitality.
Regular glutathione IV treatments can lead to improved energy levels, clearer skin, and better mental clarity. Additionally, it’s an effective strategy for athletes looking to enhance their performance and recovery. The clinics in Oakville providing this service are equipped with trained healthcare professionals who tailor treatments to meet individual health needs.
Conclusion Exploring natural and integrative health services can provide profound benefits for your overall well-being. Whether you are seeking the personalized care of a naturopathic doctor in Mississauga, the targeted benefits of a fertility acupuncture clinic in Oakville, or the rejuvenating effects of glutathione IV therapy in Oakville, the Greater Toronto Area offers a wealth of options to support your health journey.
#glutathione iv therapy mississauga#Naturopath milton#Glutathione iv therapy oakville#IV therapy Milton#Naturopath clinic milton#Naturopathic doctor in oakville
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Tubal Occlusion and Its Etiology: Insights into a Key Infertility Factor with a Fertility Doctor Toronto
Tubal occlusion, commonly known as blocked tubes, significantly contributes to female infertility. This condition, characterized by the obstruction of the fallopian tubes, impedes the egg's transit from the ovaries to the uterus, thereby thwarting the confluence of egg and sperm, essential for conception. Comprehending the etiological factors, diagnostic approaches, and the amalgamation of medical and natural therapeutic strategies is imperative in addressing infertility under the guidance of a Toronto-based fertility specialist.
Etiology of Tubal Occlusion The obstruction of the fallopian tubes can be attributed to various etiological agents, including:
Pelvic Inflammatory Disease (PID): Predominantly a sequelae of sexually transmitted infections, such as chlamydia or gonorrhea, PID can culminate in the formation of scar tissue, leading to the obstruction of the fallopian tubes.
Endometriosis: This condition, where tissue similar to the lining of the uterus grows outside the uterus, can cause adhesions that block the tubes.
Previous Pelvic Surgery: Surgeries involving the pelvic organs, including the uterus, ovaries, and fallopian tubes, can lead to scar tissue formation and blockages.
Ectopic Pregnancy: A pregnancy that occurs in the fallopian tube can damage the tube and lead to blockage.
Certain Sexually Transmitted Infections (STIs): Untreated STIs can cause inflammation and scarring in the fallopian tubes.
Diagnosis
The identification of tubal occlusion, commonly known as blocked tubes, predominantly employs advanced medical imaging techniques, typically conducted by a fertility specialist in Toronto. The most common diagnostic method is the Hysterosalpingogram, commonly abbreviated as HSG. This procedure entails an X-ray examination in which a contrast dye is administered into the uterus and fallopian tubes to facilitate the visualization of any obstructions.
Medical Treatments
Medical intervention for unblocking fallopian tubes usually involves surgery. The specific procedure depends on the location and extent of the blockage:
Laparoscopic Surgery: This minimally invasive surgery can remove blockages or scar tissue from the fallopian tubes.
Tubal Ligation Reversal: If the blockage is due to a previous tubal ligation (a type of sterilization), a reversal surgery can sometimes restore fertility.
Fertility Treatments: In cases where surgery is not viable or successful, assisted reproductive technologies like In Vitro Fertilization (IVF) can be an alternative, as they bypass the fallopian tubes entirely.
Natural Methods
In conjunction with medical treatments, certain natural methods may support the health of the fallopian tubes:
Fertility Massage: This specialized form of massage aims to increase circulation to the reproductive organs, potentially helping to reduce adhesions and blockages.
Herbal Medicine: Some herbal supplements are believed to have anti-inflammatory properties that might help in reducing scar tissue and inflammation in the fallopian tubes.
Acupuncture: As part of traditional Chinese medicine, acupuncture may improve reproductive health by increasing blood flow and balancing hormones.
Diet and Lifestyle Changes: A healthy diet rich in antioxidants, vitamins, and minerals can support overall reproductive health. Regular exercise and avoiding smoking and excessive alcohol consumption can also be beneficial.
Castor Oil Packs: Applied externally, castor oil packs are thought to enhance circulation and promote healing of bodily tissues, including the fallopian tubes.
Combining Methods
The combination of medical and natural methods should be tailored to each individual's situation by a fertility doctor Toronto. It is essential to consult with healthcare professionals, including fertility specialists and holistic health practitioners, to develop a comprehensive treatment plan. This plan should address not only the physical aspects of tubal blockage but also the emotional and psychological impacts of dealing with fertility challenges.
In conclusion, while blocked tubes present a significant barrier to fertility, there are multiple avenues for treatment and management. A combination of medical interventions and supportive natural methods can offer hope and improve the chances of conception for many women facing this challenge.
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Some facts about Acupuncture for digestion
Acupuncture for digestion has been proven to be useful in the treatment of nausea and vomiting, functional problems (inflammatory bowel disease, constipation, and diarrhea), peptic ulcer disease, Crohn's disease, perioperative ileus, and even gall stone disease in pilot investigations.
Acupuncture for Digestive Issues:-
Acupuncture for digestive issues is the process that once the food is swallowed, digestion begins in the mouth. Food is broken down and prepared for passage through the digestive (gastrointestinal) tract by chewing and saliva. Peristalsis sends food further downhill into the stomach as it passes through the throat and esophagus. The stomach produces acid to break down food, begin nutritional absorption, and prepare the food for passage to the small and large intestines. Because nutrients are extracted and by-products are transported to the large intestines for faces, absorption occurs largely in the small intestine.
The liver, gallbladder, and pancreas are accessory organs that serve a supplementary function in digesting. Bile is secreted by the liver, which aids in the breakdown of lipids (fats) and the detoxification of toxins. By storing and secreting bile as needed, the gallbladder collaborates with the liver. The pancreatic is a muscle that generates digestive enzymes and regulates blood sugar.
How Can Acupuncture and Chinese Medicine Help With Digestive Problems?:-
Chinese medicine for digestive issues Toronto and acupuncture for hormonal imbalance Toronto Bloating, constipation, diarrheas’, nausea, cramping, and abdominal pain are all signs that things aren't moving through your digestive tract as quickly as they should. Chronic stress, poor food, poor sleep patterns, and other lifestyle concerns are frequently the fundamental causes of digestive problems.
Acupuncture for balancing hormones Toronto relieves stress by regulating the gut-brain axis and neurological system, which improves digestive function. Reduced digestive function is one of the negative consequences of an overactive sympathetic nervous system. Acupuncture also aids in the reduction of pain and inflammation, which aids in the regulation of stomach acid and the promotion of peristalsis.
Chinese medicine for digestive issues in Toronto are frequently used to treat digestive problems, either alone or in combination with acupuncture. They are taken internally and act in the same way that food supplements or dietary changes do to help with digestion. Many civilizations throughout the world have employed common herbs like ginger and liquor ice for hundreds of years to help with digestion.
Acupuncture and Chinese medicine, when used together, can help with the following digestive problems (and others):
ü Bloating
ü Constipation
ü Diarrhea
ü Vomiting and nausea
ü Pain in the abdomen
ü IBS
ü Crohn's disease is a chronic inflammatory bowel illness that affects
ü Reflux of acid
ü Colitis ulcerative
#acupuncture for digestion#acupuncture for digestive issues#chinese medicine for allergy#chinese herbs for hormonal imbalance#chinese herbs for hormonal imbalance toronto#chinese medicine for hormonal imbalance toronto#acupuncture for hormone imbalance toronto#acupressure for hormonal imbalance toronto#CHINESE MEDICINE for ENDOMETRIOSIS TORONTO#CHINESE MEDICINE for ENDOMETRIOSIS TREATMENT TORONTO#CHINESE MEDICINE FOR MIGRAINE IN TORONTO
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Naturopathic Treatment For Endometriosis
Endometriosis is a relatively common condition that can cause massive amounts of pain and discomfort, especially around your period.
Like many other chronic illnesses, endometriosis comes with inflammation – it’s this inflammation that may be the cause of endometriosis pain.
If you’re dealing with endometriosis, you aren’t alone — and there are naturopathic treatments to help alleviate your symptoms.
Today, we’re going to look at some of the most effective natural treatments for endometriosis.
What Is Endometriosis?
Endometriosis is a chronic disorder that causes tissue to grow endometrial tissue on organs outside your uterine cavity.
This tissue can grow on your ovaries, pelvic lining, and bowel.
Your uterine lining, or endometrium, is lined with a similar tissue.
Menstruation causes your hormone levels to fluctuate, which inflames this extra tissue.
The misplaced tissue will grow and thicken, eventually breaking down without any means of leaving your pelvic area.
This can lead to a number of uncomfortable and painful symptoms, which often spike around your period.
What Causes Endometriosis?
Unfortunately, the exact cause of endometriosis is unknown.
There are some theories that have circulated for years, such as "retrograde menstruation".
Retrograde menstruation occurs when menstrual blood enters your pelvic cavity via the fallopian tubes instead of leaving your body through your vagina like normal.
Another suspected cause theorizes that hormones cause the cells outside your uterus to transform into cells similar to those inside your uterus.
Others speculate endometriosis may be caused by an issue with the immune system, the transportation of uterine cells through the lymphatic system, or cell tissue misplaced during the fetal period reacting to hormones during puberty.
There are so many potential causes and yet, we do not ultimately know what causes endometriosis.
What we do know is it ranges in severity, which we track through four stages: minimal, mild, moderate, and severe.
Like many other chronic illnesses, the symptom severity can vary.
However, the degree of pain or discomfort you feel does not necessarily correlate to the severity of your condition.
Let’s look at the signs and symptoms associated with endometriosis.
Symptoms Of Endometriosis
Regardless of severity, the most commonly experienced symptom of endometriosis is pelvic pain.
There are a number of additional symptoms caused by the inflamed misplaced tissue, including:
Irritation
Fertility issues
Severe pain during menstruation
Lower back pain
Scar formation
Adhesions (tissue binding pelvic organs together)
Digestive issues like bloating, diarrhea, nausea, or constipation during menstruation
Endometrial cysts
Stress and low mood
If you’re experiencing these symptoms, talk to your doctor to investigate whether endometriosis may be the cause.
Naturopathic Treatments For Endometriosis
Endometriosis can be immensely painful, especially during your period.
The efficacy of treatment options varies depending on your specific symptoms, and your naturopathic doctor or other medical provider can help you find which one is right for you and your body.
Endometriosis presents both acute and long-term issues, so some treatments are geared at reducing overall inflammation while others are meant to help with current symptoms.
Overall, it’s important to ease pain and your stress response while also tackling the bigger issues like supporting your immune system, balancing hormone levels, and encouraging a healthy inflammatory response.
Let’s look at five effective natural treatments for endometriosis.
1. Bioidentical Hormone Replacement Therapy (BHRT)
Hormone levels are crucial when it comes to managing the inflammation and symptoms of endometriosis.
Endometriosis has been connected to high levels of estrogen, which is responsible for endometrial tissue growth.
Reducing or limiting estrogen production can be beneficial for endometriosis treatment.
Bioidentical hormone replacement therapy, or BHRT, is the supplementation of two of your body’s natural hormones – estrogen and progesterone.
Progesterone is a hormone that counteracts estrogen, limiting the production of endometrial tissue and ultimately reducing your symptoms.
BHRT may be an effective natural solution for endometriosis, because it targets the problem at its source: fluctuating hormone levels, and improper tissue growth.
The natural progesterone used in this kind of BHRT is derived from plant oils and fats, and modified to be identical to the progesterone produced by your body.
If you’re interested in pursuing the benefits of this hormone therapy, talk to your naturopathic doctor for more information.
2. Curcumin
Known as the main compound in turmeric responsible for its bright orange-yellow hue, curcumin is an anti-inflammatory antioxidant.
Not only that, but it also slows the growth of endometrial cells by inhibiting estradiol production.
Estradiol is one of three types of estrogen produced by the human body.
Studies have shown how curcumin supplementation suppresses endometrial cell growth, thereby alleviating the symptoms of endometriosis.
Turmeric is the best dietary source of curcumin, though to ensure maximum absorption you should look to consume black pepper alongside turmeric.
This is because the piperine in black pepper boosts curcumin absorption.
Consuming turmeric alongside healthy fats also increases its effectiveness by causing the curcumin to be absorbed straight into your blood stream.
3. Omega-3 Oils
Inflammation can be caused and worsened by a variety of factors, but one of the main causes is prostaglandins.
Prostaglandins are a group of fatty acids responsible for menstrual cramps and endometrial pain.
Not all prostaglandins are "bad", however; there are also "good" ones known to decrease inflammation.
The important thing is to ensure there is a balance of these fatty acids within your body.
Omega-3 fatty acids are beneficial for those with endometriosis because your body converts them to anti-inflammatory prostaglandins.
Plus, they help reduce the production of "bad" prostaglandins that cause inflammation (which can be found in red meat and dairy).
The best dietary sources of omega-3s are fatty fish such as salmon and tuna, as well as nuts and seeds.
Omega-3 fatty acid supplements are also easy to find at most dispensaries and health food stores.
4. Acupuncture
The benefits of acupuncture are wide-reaching and may be an effective treatment to help with endometriosis.
Acupuncture, one of the main components of traditional Chinese medicine, is a process in which tiny needles are inserted along certain points of your body.
This treatment may alleviate inflammation and reduce stress, as well as reduce the abdominal and pelvic pain associated with endometriosis.
Additionally, acupuncture has an impact on the growth of endometrial tissue outside of the uterus.
5. Dietary Changes
The foods you eat can have a big impact on your health, especially if you’re suffering from a chronic inflammatory condition like endometriosis.
Studies have shown the link between diet and endometriosis, with foods like fruits and vegetables decreasing your risk of developing this disorder.
Certain foods are known to increase your chances of developing endometriosis and worsen inflammation in existing cases, such as red meat.
Another reason to avoid meat as well as high-fat dairy products is due to toxins known to accumulate in animal-based fats.
These toxins, dioxin and polychlorinated byphenyls (PCBs), can exacerbate endometriosis symptoms and severity.
High-fibre foods are a great option to help regulate your gastrointestinal system, which has a strong overall impact on inflammation.
You may not have heard of isoflavones, but they are a powerful tool in your fight against endometriosis and its associated symptoms.
Isoflavones are plant-based chemicals that inhibit the conversion of androgens to estrogens, and they block more potent natural estrogens from binding to the relevant receptor.
Good dietary sources of isoflavones include:
Beans such as soybeans, chickpeas, and fava beans
Peanuts and pistachios
Celery
Parsley
Indoles, an organic compound found in cruciferous vegetables such as broccoli and cabbage, have similar anti-estrogen effects.
Book An Appointment With Annex Naturopathic
The pain of endometriosis can be unbearable, and it may seem like you’ve run out of options.
There are naturopathic treatment solutions that can have a profound impact on your condition, thereby improving your overall quality of life.
For more resources and information on natural endometriosis treatment options, contact us at Annex Naturopathic.
Our women-lead team of experienced naturopaths would love to work with you on a personalized treatment plan that fits your lifestyle.
You don’t have to suffer in silence — we’re here to help.
Book an appointment with Annex Naturopathic today.
If you’re curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.
Yours in Health,
Dr. Tanya Lee, N.D
Annex Naturopathic Clinic
572 Bloor St W #201, Toronto, ON M6G 1K1 -https://goo.gl/maps/uVRBvcyoUa62
Annex Naturopathic Clinic is a clinic in Toronto that offers integrative healthcare solutions from Drs. Marnie Luck, ND, and Tanya Lee, ND
See more tips on health, wellness, naturopathy, and medicine at: naturopathic doctor
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ALIVE Holistic Health Clinic
Address: 2 Carlton St Toronto, ON M5B 1J3
Phone: 416-591-1535
Web: https://aliveholistichealth.ca
Acupuncture. Fertility Clinic, Massage Therapy
Acupuncture, Fertility Acupuncture, Naturopathic Medicine
Based in Toronto, Ontario, ALIVE Holistic Health Clinic takes a holistic approach to your health. We treat pain, fertility issues, provide stress relief and many women’s and Men’s health issues. Our treatments include acupuncture, massage, laser therapy, Maya abdominal Therapy, naturopathic medicine, Chinese herbal medicine and hypnosis. If you have been struggling to get pregnant, our fertility treatments can help. We commonly treat conditions like PCOS and endometriosis. We would love to hear from you!
Business Hours: Monday 9:00am - 6:30pm, Tuesday & Wednesday 10:00am - 6:30pm, Thursday & Friday 8:00am - 6:30pm, Saturday 9:00am - 6:30pm, Sunday 10:30am - 3pm
Owner: Mary Wong
Business Email: [email protected]
Yesr EST: 2004
Payment: Cash, Debit Cards, all major credit cards, Visa, MasterCard, Amex
Social: https://www.facebook.com/ALIVEHolisticHealthClinic/ https://twitter.com/aliveholistichealth https://www.instagram.com/marywongrtcmp/ https://ca.linkedin.com/in/mary-wong-aa17b88
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Endometriosis is one of the best gynecological discarders that affect roughly 10% of reproductive age women globally. Endometriosis happens when endometrial tissue becomes on you ovaries, entrails and tissues coating your pelvis.
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Estrogen Dominance: The Hormone Imbalance You’re Told You Don’t Have
As a female naturopathic doctor, I have a a great deal of experience in women's health issues. Much of it treating conditions like hormone imbalances and their effects on our quality of life.
Hormone imbalances are a complicated thing though.
Often times women will feel that their hormones are off, but after blood work and basic analysis, it’s likely that everything will come back “normal”.
So how is it that hormones are normal, yet one day your body feels completely off, or that you one day find that you have fibroids? or endometriosis? or fertility issues?
What are some of the signs and symptoms that could lead you to potentially prevent and actually treat these conditions, instead of coming up with band-aid solutions to cover up the symptoms?
What is Estrogen Dominance?
Estrogen dominance is a hormonal condition that is often never detected in conventional medicine - the term dominance may indicate that a high level of estrogen would be detected on routine blood work, but this is not often the case.
In fact, estrogen typically comes back “within normal range” in women who have estrogen dominance - how is this so?
This is because estrogen dominance is a functional hormonal imbalance and is not a “excess” condition.
A functional hormonal imbalance indicates that while the body is clearly performing daily as it should, there are signs and symptoms that one experiences, whether it be mild or debilitating, indicate that the overall system is compromised.
This may not be a big deal, but if undetected and left untreated, can lead to chronic disease.
Signs and Symptoms of Estrogen Dominance
The interesting thing about estrogen dominance is that it’s highly common in our society - many women experience symptoms of estrogen dominance monthly, some more severely than others.
The typical symptoms of estrogen dominance include:
PMS symptoms such as irritability, breast tenderness/swelling, premenstrual pain, acne, constipation, bloating, headaches
Painful periods
Irregular periods
Insomnia
Cyclical moodiness
Many women experience these symptoms and are told they are “normal”.
They are considered normal because these symptoms are a “societal norm”, meaning that many people have these symptoms so therefore it’s normal, but from a health perspective, this is not normal!
If you have mild symptoms, it’s likely that you’re fine, but if any of these symptoms become severe and affect your day to day living, you definitely should consider being assessed for estrogen dominance.
Mainstream treatment for these symptoms usually involve being on hormonal contraception (birth control), anti-depressants, or pain-medications, and while these may help control your symptoms, none of these solutions actually target the root cause.
If the root cause isn’t treated, it can lead to chronic disease
Associated Symptoms
When you have increased amounts of estrogen in your body, this can highly affect estrogen-sensitive tissues.
The tissues that are most affected are in the breast and uterus.
Why is breast tenderness and swelling caused by estrogen-dominance?
It’s because your breast tissue is hyper-stimulated.
Why do you feel pain during your menstrual flow, or experience extremely heavy flows when you have estrogen-dominance?
This is because your uterine lining is hyper-stimulated by estrogen dominance.
When these tissues are hyper-stimulated, that leads to “cell proliferation” - long term cell-proliferation in the breast can lead to breast cancer.
Long-term cell proliferation in the uterus is called endometrial hyperplasia, which is a risk factor for uterine fibroids, endometriosis and uterine cancer.
What causes estrogen dominance?
Estrogen dominance is when there is an abundance of estrogen wrecking havoc on the body that isn’t being balanced by other hormones, or properly cleared by the liver.
Reasons for why someone can have estrogen dominances are stemmed from:
Biochemical imbalances and genetic-related dysfunction of liver detoxification
Increased estrogen production due to chemical exposure and inflammation
Relative excess due to another hormone deficiency
Environmental and dietary exposure to xenoestrogens.
I will go through each of these reasons in detail in upcoming articles.
Today we will focus on liver detoxification.
Estrogen and liver detoxification
Estrogen is activated and then detoxified by the liver.
Liver detoxification occurs in phases.
Phase 1 Liver Detoxification
Phase 1 is responsible for exposing a hydroxyl-group (OH) to the estrogen (estrone E1 for this discussion) molecule, which breaks it down to many different estrogen “metabolites” with this OH group.
Each metabolite has it’s own impact and function on the body. When the liver is working properly, it breaks estrogen down so the ratio of these metabolites favour optimal estrogen effect: an abundance of the protective 2-OH-E1 metabolite.
When the liver is having problems with phase 1, then it may favour the production of other estrogen metabolites, ones that have carcinogenic (cancer-causing) effects on the estrogen-sensitive tissue - these metabolites are 16-OH-E1 and 4-OH-E1.
The reason why the liver may favour the production of some metabolites versus the other comes down to which enzymes are activated. 2-OH-E1 is produce through the CYP1A1 enzyme, 4-OH-E1 through CYP1B1 and 16-OH-E1 CYP3A4, all of these are part of Phase 1 enzyme system called the Cytochrome P450 system.
One could have a genetic abnormality in the enzyme for 2-OH-E1 (CYP1A1), or could be lacking the essential “cofactors” to the enzyme, rendering the enzyme more sluggish and unable to keep up with 2-OH-E1 production.
One could also be exposed to environmental toxins that can also render the enzyme functionally slow, or simply have a diet that isn’t rich in foods that favour the production of 2-OH-E1.
Or for some reason, the enzymes for 4 and 16-OH-E1 can be upregulated, favouring their production over 2-OH-E1.
Phase 2 Liver Detoxification
Phase 2 is all about conjugation - binding the now hydrolyzed estrogen to a methyl-group to exert further effects of the body and to prepare the estrogen for excretion out of the body.
2-OH-E1 and 4-OH-E1 are conjugated by the same enzyme called COMT - this enzyme is essential for turning these in to 2 and 4 -methoxy-E1. 2-methoxy-E1 is protective to the body, while 4-methoxy-E1 is neutralized by this process.
COMT is also important for producing antioxidants by the liver, which are protective against cancers. Therefore, if this enzyme is dysfunctional (for reasons as suggested for the other enzymes above), then the protective and neutralizing effects are diminished.
In fact, studies found that women who have genetic abnormalities in the COMT gene had higher risk for estrogen-related disease, such as uterine fibroids, endometriosis, breast and uterine cancer (see below for references).
This genetic susceptibility also has been found to be dependent on ethnicity - for example women of African descent being the one of the most susceptible groups for uterine fibroids.
What we do know is that liver health is important for regulation of estrogen-metabolism and can play a significant role on how we develop estrogen-related disease.
Our phase 1 and phase 2 health decline as we age, our exposure to environmental pollutants and our nutrition. Take a look at our article on Liver Health to find out ways we can improve the strength and functionality of our detoxification processes, potentially improving our estrogen health.
Next week we will go through how inflammation, and other hormone imbalances can be associated with estrogen dominance and nutritional and herbal strategies to improve our overall hormonal health and to prevent chronic disease.
If you’re curious to learn more about this subject or would like to consult with one of our NDs feel free to book a visit or contact us.
Yours in Health,
Dr. Tanya Lee, N.D Annex Naturopathic Clinic 572 Bloor St W #201, Toronto, ON M6G 1K1 -https://goo.gl/maps/uVRBvcyoUa62
References
1) Shen Y et. al. Role of single nucleotide polymorphisms in estrogen-metabolizing enzymes and susceptibility to uterine leiomyoma in Han Chinese: a case-control study.J Obstet Gynaecol Res. 2014 Apr;40(4):1077-84.
2)Huang CS et. al. Breast cancer risk associated with genotype polymor- phism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic study on cancer susceptibility. Cancer Res 1999. 59:4870–4875
3) Al-Hendy A, Salama SA., Catechol-O-methyltransferase polymorphism is associated with increased uterine leiomyoma risk in different ethnic groups.J Soc Gynecol Investig. 2006 Feb;13(2):136-44.
4) Zhao XM., et. al. Polymorphism of catechol-o-methyltransferase gene in relation to the risk of endometrial cancer. Zhonghua Fu Chan Ke Za Zhi.2007.42:116–119
5)Juo SH, et. al., CYP17, CYP1A1 and COMT polymorphisms and the risk of adenomyosis and endometriosis in Taiwanese women. Hum Re-prod 2006. 21:1498–1502
To find more tips on health, wellness, and alternative medicine, please visit us here: naturopathic doctor toronto
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