#Bioengineered Artificial Skin Market Demand.
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Artificial Skin Market Poised to Grow at Highest Pace Owing to Rising Burn Injuries
The artificial skin market deals with products that act as a temporary or permanent synthetic skin replacement for burn victims or those suffering from skin diseases or disorders. Artificial skins contain live cells or are made from biocompatible materials that mimic natural skin's structure and functions. They offer barrier protection against infection and fluid loss while promoting wound healing. With rising burns and traumatic injuries worldwide, the demand for skin grafts and substitutes is expanding rapidly. The Global bioengineered artificial skin market is estimated to be valued at US$ 3.32 Billion in 2024 and is expected to exhibit a CAGR of 16% over the forecast period 2023 to 2030. Key Takeaways Key players operating in the bioengineered artificial skin market are Genoskin, Smith and Nephew Inc., Genzyme Biosurgery, Vericel Corporation, AROA BIOSURGERY LIMITED, Integra LifeSciences Corp, COOK BIOTECH, Mölnlycke Health Care AB, Avita Medical, MiMedx Group, Inc., and Organogenesis Holdings Inc. The global artificial skin market is driven by the rising incidence of burn injuries, especially in developing nations where industrial safety norms are still evolving. As per the World Health Organization (WHO), over 300,000 people die annually from burns worldwide. Moreover, the increasing application of artificial skins in wound care management and reconstruction surgeries is also fueling market revenue. Technological advancements focus on developing skin substitutes that resemble natural skin more closely. Researchers are working on creating multilayered, vascularized artificial skins with hair follicles, sweat glands, and seamless integration with the recipient's skin. Such next-gen artificial skins can help achieve superior cosmetic outcomes and quality of life for patients. Market Trends Some key trends in the artificial skin market include the development of bioprinted and 3D printed skin substitutes. Researchers are adopting advanced bioprinting methods to develop patient-specific skin substitutes by combining skin cells and biomaterials through 3D printing. This facilitates mass production of artificial skins with precise anatomical features. Another trend gaining traction is the incorporation of advanced therapies into artificial skins. For example, combining stem cell therapy and skin grafting/substitutes to accelerate wound healing. Such combination therapies may enable developing "smart skins" capable of tissue regeneration. Market Opportunities The growing demand for skin tissue engineering and regenerative therapies in underpenetrated regions presents significant opportunities for artificial skin market players. Expanding access to advanced wound care and burns management in rural healthcare systems also opens lucrative prospects. Customization capability is another opportunityarea. As artificial skins become more affordable, customizable options specific to wound type, location, and patient needs can augment the market potential.
#Bioengineered Artificial Skin Market Growth#Bioengineered Artificial Skin Market Trend#Bioengineered Artificial Skin Market Demand.
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The Role of Artificial Intelligence in the Global Medical Collagen Market
The global medical collagen market revenue is experiencing a significant upward trend, with a valuation of USD 708.98 million in 2023. Projections indicate that this market will reach USD 1.14 billion by 2031, growing at a compound annual growth rate (CAGR) of 6.1% during the forecast period from 2024 to 2031. This growth reflects the increasing demand for collagen-based products in various medical applications, including wound healing, orthopedic surgeries, and aesthetic treatments.
Medical collagen, a natural protein found in the connective tissues of humans and animals, is highly valued for its biocompatibility, biodegradability, and ability to promote tissue regeneration. These properties make it an essential component in a wide range of medical products, from sutures and implants to topical gels and injections.
Key Market Drivers
Rising Demand in Wound Care: The growing prevalence of chronic wounds and surgical procedures is driving demand for medical collagen. Collagen-based dressings and gels are becoming increasingly popular due to their ability to promote faster healing and tissue regeneration. As the global aging population continues to rise, the need for effective wound care solutions is expected to fuel market growth.
Increased Use in Aesthetic Procedures: The expanding aesthetic medicine market is another significant driver for the medical collagen market. Collagen fillers are widely used in cosmetic procedures to reduce wrinkles and improve skin elasticity. As more individuals seek non-invasive cosmetic treatments, the demand for collagen-based products is expected to rise.
Advancements in Research and Development: Continuous research and innovation in the field of medical collagen are leading to the development of new and improved products. Advances in extraction and purification technologies are enhancing the quality and effectiveness of collagen-based therapies. Furthermore, the exploration of collagen derived from various sources, including fish and plants, is opening new avenues for market expansion.
Growing Awareness of Regenerative Medicine: The increasing focus on regenerative medicine is propelling the demand for collagen in various therapeutic applications. Collagen plays a crucial role in tissue engineering and regenerative therapies, making it a key ingredient in developing innovative treatments for various medical conditions.
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Challenges and Opportunities
Despite the market’s growth potential, challenges such as high production costs and regulatory hurdles may hinder progress. However, the growing interest in sustainable sourcing and the development of bioengineered collagen present new opportunities for market players. As consumers become more conscious of the environmental impact of their choices, collagen derived from sustainable sources is gaining traction.
Regional Insights
North America currently dominates the medical collagen market, attributed to the presence of leading healthcare companies, advanced research institutions, and a high demand for aesthetic treatments. Europe follows closely, with a strong emphasis on wound care management and regenerative medicine. The Asia-Pacific region is expected to witness the highest growth rate during the forecast period, driven by increasing healthcare investments and rising awareness of advanced medical solutions in countries like China, India, and Japan.
Future Outlook
As the medical collagen market continues to evolve, a CAGR of 6.1% from 2024 to 2031 indicates promising growth. The increasing demand for innovative healthcare solutions, coupled with advancements in collagen research, is expected to propel the market to new heights.
In conclusion, the medical collagen market is set for significant expansion, with a valuation projected to rise from USD 708.98 million in 2023 to USD 1.14 billion by 2031. This growth is driven by rising demand in wound care and aesthetic procedures, advancements in research and development, and the increasing focus on regenerative medicine. As the healthcare landscape evolves, medical collagen will play an integral role in shaping the future of medical treatments and therapies.
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Beyond Borders: The Global Tissue Engineered Skin Substitute Market Offers Hope for Millions
The global tissue engineered skin substitute market is projected to be worth US$ 2.4 billion by 2024. The market is projected to reach US$ 3.5 billion by 2034. From 2024 to 2034, the market is projected to expand at a compound annual growth rate (CAGR) of 3.9%. The growing need for minimally invasive surgeries, the aging population, the increase in diabetic foot ulcers, the rise in vascular diseases and burn injuries, the improvements in healthcare infrastructure, and the increased government investment are the main factors expected to propel the growth of the tissue engineered skin substitute market.
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More biomimetic tissue structures have been developed as a result of tissue engineering and the enhanced capacity to integrate biomaterials and cell culture systems with contemporary manufacturing techniques. Improvements in technology are paving the way for better skin substitutes made of tissue. Intriguing biofabrication methods for the creation of bioengineered skin substitutes are biotextiles and 3D bioprinting. A US research team has created a method that makes it possible to print whole blood vessels and skin in three dimensions. Such state-of-the-art fabrication techniques will open up a substantial market opportunity worldwide.
Though significant advancements have contributed to the expansion of the market, certain limitations still exist. The inability of tissue-created skin substitutes to grow skin appendages like hair follicles, sebaceous glands, and nails is one of the biggest challenges facing R&D teams.
Key Takeaways – Tissue Engineered Skin Substitute Market Study
Demand for biologic skin substitutes is expected to rise during the forecast period due to increased tissue engineering research. Engineers from Caltech and ETH Zurich, for example, developed an artificial skin out of pectin, a naturally occurring long-chain polymer found in plant cell walls that allows the production of natural and fresh dermis.
Diabetes and chronic wounds are growing increasingly widespread, resulting in an increase in demand for tissue engineered skin substitutes.
The incidence of diabetic foot ulcers, venous leg ulcers, and pressure ulcers is expected to drive demand for tissue engineered skin substitutes in developing nations such as China and India.
Leading Manufacturers Setting the Pace for Product Innovations
The tissue engineered skin substitute market is a consolidated market. The tier 1 companies in the tissue engineered skin substitute market such as Allergan Plc., Mimedex Group Inc., Integra LifeSciences Corp. and Integra LifeSciences Corp. are expected to hold more than half of the total revenue generated by tissue engineered skin substitutes. The key players in the market are reshaping their current product portfolio by focusing on the introduction of new and advanced technologies and innovating new products.
Key Players:
Smith & Nephew plc.
Acelity L.P. Inc.
Mölnlycke Health Care
Integra Life Sciences
Allergan plc
Regenicin
Organogenesis Inc.
MiMedx
LifeNet Health
Kerecis
Medline Industries, Inc.
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Tissue engineered skin substitute market, a new study from Future Market Insights, opines on the evolution of tissue engineered substitute market from 2014 to 2021 and presents demand projections from 2022 to 2029 on the basis of; product (acellular skin substitute, biologic skin substitute, cellular skin substitute and synthetic substitute), material (synthetic and natural), application (chronic wound, acute wound and other applications such as breast reconstruction etc.) and end user (hospital, specialty clinics, ambulatory surgical centres and research laboratories) across seven prominent regions.
Tissue Engineered Skin Substitute Market by Category
By Product:
Acellular Skin Substitutes
Acellular skin substitutes based on Amniotic Membrane
Other Acellular skin substitutes
Biologic Skin Substitute
Allograft
Xenograft
Cellular Skin Substitutes
Cellular skin substitute based on amniotic membrane
Other cellular skin substitutes
Synthetic Skin Substitutes
By Material:
Synthetic
Natural
By Application:
Chronic Wounds
Venous leg Ulcers
Diabetic Foot Ulcer
Pressure Ulcers
Acute Wounds
Traumatic Wounds
Burn Cases
Other Applications
By End User:
Hospital
Specialty Clinics
Ambulatory Surgical Centers
Research Laboratory
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Growing Bioengineered Artificial Skin Market Poised to Witness Robust Expansion During 2023-2030
Bioengineered artificial skin refers to lab-grown human skin that mimics natural skin. It helps treat severe burns and other wounds by protecting tissues from infections and fluids loss. Significant advances have been made in developing bioengineered artificial skin that closely resembles natural skin tissue in composition, function and appearance. The artificial skin substitutes facilitate faster healing and avoid complications associated with skin grafting from other parts of the body. Growing prevalence of burn injuries and skin disorders has increased the demand for these skin substitutes globally. The global bioengineered artificial skin market is estimated to be valued at US$ 3.32 Billion in 2024 and is expected to exhibit a CAGR of 16% over the forecast period 2023 to 2030. Key Takeaways Key players operating in the bioengineered artificial skin market are Genoskin, Smith and Nephew Inc., Genzyme Biosurgery, Vericel Corporation, AROA BIOSURGERY LIMITED, Integra LifeSciences Corp, COOK BIOTECH, Mölnlycke Health Care AB, Avita Medical, MiMedx Group, Inc., and Organogenesis Holdings Inc. Market Trends The growing trend towards cell-containing skin replacements have moved regenerative medicine forward. Researchers are developing skin substitutes containing keratinocytes, melanocytes and fibroblasts to mimic natural skin better. Tissue-engineered skin substitutes are increasingly common over biosynthetic skin grafts. They mimic the complexity and biomechanics of natural skin closer than acellular skin substitutes. Advances in biofabrication techniques have enabled the large-scale production of tissue-engineered skin grafts. Market Opportunities The development of bioengineered skin with functional appendages like hair follicles, sebaceous glands and sweat glands presents lucrative opportunities. It can help restore skin's barrier function better and improve aesthetic outcomes. Personalized bioengineered skin using patient-specific cells offers strong market potential. 3D bioprinting and tissue engineering approaches allow manufacturing skin grafts tailored for individual patients' anatomy and physiology. Impact of COVID-19 on Bioengineered Artificial Skin Market The COVID-19 pandemic has significantly impacted the bioengineered artificial skin market. During the initial outbreak and lockdowns imposed worldwide, demand for artificial skin was low as non-essential medical procedures were postponed. Supply chain disruptions and shortage of raw materials also hindered production activities. However, post lockdowns, the demand started picking up again as elective surgeries resumed. The pandemic highlighted the importance of this market as artificial skin is used for treating severe burns and other traumatic wounds. North America Region for Bioengineered Artificial Skin Market The North America region accounts for the largest share of the global bioengineered artificial skin market in terms of value. This is primarily attributed to factors such as the rising incidence of burns and traumatic injuries, growing elderly population susceptible to chronic wounds, favorable regulatory environment, strong healthcare infrastructure and higher adoption of advanced treatment options. Countries like the United States have several registered skin graft products and ongoing clinical trials. Asia Pacific as the Fastest Growing Region The Asia Pacific region is poised to grow at the fastest pace in the global bioengineered artificial skin market owing to a swiftly increasing patient pool, rising medical tourism and improving access to healthcare. Rapid economic development and rising affluence have been instrumental in market growth. China, India and other ASEAN countries are witnessing significant development of healthcare facilities and increasing healthcare expenditures.
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Global Bioengineered Artificial Skin Market Is Estimated To Witness High Growth Owing To Rising Demand for Advanced Wound Care Solutions
The global Bioengineered Artificial Skin Market is estimated to be valued at US$ 3.16 billion in 2022 and is expected to exhibit a CAGR of 21.5% over the forecast period of 2023-2030, as highlighted in a new report published by Coherent Market Insights. Market Overview: Bioengineered artificial skin refers to the artificially grown or manufactured skin tissue that can be used to treat severe burns, chronic wounds, and other skin-related conditions. This advanced wound care solution offers several advantages over traditional wound care methods, including enhanced wound healing, reduced scarring, and improved aesthetic outcomes. The growing prevalence of chronic wounds, increasing demand for regenerative medicine, and advancements in tissue engineering technologies are driving the growth of the bioengineered artificial skin market. Market Key Trends: One key trend in the bioengineered artificial skin market is the increasing adoption of bioactive dressings. Bioactive dressings are designed to actively promote wound healing by providing a conducive environment for cell growth and tissue regeneration. These dressings are enriched with bioactive substances, such as growth factors, cytokines, and extracellular matrix components, which accelerate the healing process. For example, Acelity L.P. Inc. offers a bioactive dressing called Promogran Prisma Matrix, which contains a combination of collagen proteins and silver for effective wound healing. PEST Analysis: Political: Government initiatives to promote wound care and regenerative medicine research, such as funding grants and regulatory support, are expected to drive market growth. Economic: Rising healthcare expenditure and increasing investments in healthcare infrastructure by both public and private sectors are favoring the market growth. Key Takeaways: 1. Market size related content: The global bioengineered artificial skin market is expected to witness high growth, exhibiting a CAGR of 21.5% over the forecast period, due to increasing demand for advanced wound care solutions. The rising prevalence of chronic wounds, burn injuries, and diabetic foot ulcers, coupled with the advantages offered by bioengineered artificial skin, are driving market growth. For instance, according to the World Health Organization (WHO), an estimated 180,000 deaths occur each year due to burns, with a significant number of survivors requiring long-term wound care. 2. Regional analysis: North America is anticipated to be the fastest-growing and dominating region in the bioengineered artificial skin market. This can be attributed to the presence of advanced healthcare infrastructure, increasing investments in research and development activities, and a higher incidence rate of chronic wounds in the region. Furthermore, favorable reimbursement policies and the presence of key market players in the region contribute to its market dominance. 3. Key players related content: Key players operating in the global Bioengineered Artificial Skin Market Scope include Smith & Nephew plc, Organogenesis Holdings Inc., Integra LifeSciences Holdings Corporation, MiMedx Group, Inc., Mölnlycke Health Care AB, Avita Medical, Stratatech Corporation, TissueTech, Inc., Stryker Corporation, Johnson & Johnson, Acelity L.P. Inc., Medline Industries, Inc., Zimmer Biomet Holdings, Inc., LifeNet Health, and ConvaTec Group plc. These players focus on strategies such as mergers and acquisitions, product innovations, and collaborations to strengthen their market position and expand their product portfolios. The global bioengineered artificial skin market is expected to witness significant growth in the coming years. The rising demand for advanced wound care solutions, increasing prevalence of chronic wounds, and technological advancements in tissue engineering are the key factors driving market growth. The market is dominated by key players who are actively involved in research and development activities to introduce innovative and effective bioengineered artificial skin products.
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How Do Skin Replacement and Substitutes Treat Skin Conditions?
Skin substitutes are made of synthetics, biosynthetic, and biologic materials, which may cover skin wounds permanently or temporarily. Similarly, skin replacements are designed to mimic the qualities of the natural skin. Skin replacement and substitution are a kind of surgery that provides a healthier look by replacing damaged or missing skin. The replaced skin develops blood vessels and connects to the skin around it within a few days.
Such treatments are in high demand, with skin burns becoming more common, awareness among consumers about their beauty surging, and cases of skin disorders increasing. Thus, the skin replacement and substitutes market is expected to achieve significant growth in the coming years. As per the AAD, medical, preventive, and prescription & non-prescription medicine expenditures for skin diseases cost the U.S. healthcare system around $75 billion every year.
Synthetic Skin Substitutes: What Are They?
Synthetic skin substitutes are made from polymers and non-biological chemicals that are not found in the natural skin. These structures should be biodegradable, stable, and create an environment conducive to tissue regeneration. It should keep its three-dimensional shape for at least three weeks, to allow blood vessels, fibroblasts, and epithelial cells to grow. If there is a significant body reaction, this procedure should be avoided since it will exacerbate the inflammatory response, perhaps leading to serious scarring. To avoid immunoreactive processes, it should be made of immune-compatible materials.
End Users of Skin Replacement and Substitutes
• Wound Care Clinics and Hospitals
Wound care clinics and hospitals offer care to patients with non-healing wounds. These places are well-organized outpatient facilities that use up-to-date treatments and procedures to help patients recover faster. According to the WHO, burns are responsible for an estimated 180,000 deaths per year, the vast majority of which occur in low- and middle-income nations.
• Beauty and Cosmetics Industry
Cosmetics and personal care items are used to clean, beautify, promote attractiveness, and change the appearance of the human body. Now, people are adopting skin replacement and substitutes to enhance beauty and appearance.
• Two Types of Skin Substitutes: Cellular and Acellular
Skin substitutes comprise a wide range of human and animal-derived cellular and acellular components designed to encourage the host to repair damaged tissue or it with functional skin. Cellular treatments, also known as bioengineered cellular therapies, use skin cells to produce cytokines and enzymes, to help the body regenerate the tissues.
The extracellular matrix for tissue growth can be made from both natural and artificial materials, such as polyglactin and collagen. Acellular products offer a non-cellular extracellular matrix, made up of a fiber substrate or other substances, into which cells can move and commence tissue regeneration.
Skin Replacement and Substitutes for Burned Skin
In the U.S., 1.25 million burn injuries need medical treatment each year, and burn-related illnesses or conditions kill 10,000 people per year, as per the National Caregivers Library. The good news is that survival rates for major burns have improved considerably in recent years. Burns that covered half the body, for example, were usually harmful. Patients with 90% body surface burns can now survive, however with long-term disability. As a result, replacing skin lost to serious burns is a critical aspect of burn patient treatment. When patients lose 80–90% of their skin due to direct contact with scorching hot liquids, fires, chemicals, electrical current, or radiation, two significant tasks must be accomplished. Firstly, a burn surgeon must get rid of the burned skin, and then, the unprotected underlying tissue must be covered quickly.
Advantages of Skin Replacement and Substitutes
The following are some of the benefits of adopting skin replacement and substitutes:
• They can be used in various situations where there is not enough skin available, such as in severe burns. • They keep away further wounds from forming, just like skin replacement. • They give interim wound protection until skin replacement may be performed. • Synthetic skin replacements are possible on large areas onf the body. • Skin replacement can be used to repair damaged skin and restore function. • This operation is excellent for skin loss caused by a variety of conditions.
Thus, skin substitutes and replacements are in high demand because of the increase in burn cases and injuries and higher awareness of people toward maintaining a beautiful body.
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Cold Plasma Market is anticipated to grow at a healthy CAGR of ~16% During 2021-2026
A partially ionized gas comprising ions, electrons, ultraviolet photons, and reactive neutrals such as radicals, excited and ground-state molecules is known as cold plasma, the fourth state of matter. Gas dissociation by electricity, microwave radiation, or heat under ambient conditions can also be used to create plasmas artificially. Due to the low heat capacity of cold plasma, it finds application in bioengineering, medicine, and therapeutics.
The Cold Plasma Market is expected to witness a CAGR of ~16% from 2021 to 2026. Growing usage of cold plasma in wound healing, the increasing occurrence of cold plasma in cancer & infectious disease treatment, rising awareness regarding cold plasma in medical, electronics & electrical, textile & food industries, and increasing demand for environment-friendly cold plasma techniques are some of the key factors driving the global cold plasma market.
Rising Acceptance of Cold Atmospheric Plasma (CAP) Therapy in Wound Healing
One of the newest and most innovative techniques in the field of plasma medicine is called cold atmospheric plasma therapy. It contains of a mixture of reactive species that convey antimicrobial activity and affect human tissues. Due to its environment-friendly and non-invasive nature, this technique has been admired and encouraged to use in different therapeutic regimes like wound healing, tissue regeneration, and skin infection management. Atmospheric pressure cold plasmas could affect different stages of wound healing by helping to activate microorganisms in the first stage and stimulate skin-related cell proliferation and migration in the following period.
Utilizing Cold Plasma in Oncology and Dentistry Boost the Cold Plasma Market Demand
Cold (non-thermal) plasma treatment can be used to stop or eliminate infections from bacteria, bacterial biofilms, fungi, and viruses. Prospects of cold plasma in dentistry and oncology look promising due to its anti-microbial properties and its cell death properties on cells. In dentistry, cold plasma showed promising results in tooth bleaching, deactivation of biofilms in teeth, instrument sterilization, and composite restoration. Promising findings obtained from in vivo and in vitro studies of cold plasma in oncology show that it will find its niche in the treatment of cancer patients in the future. However, more studies need to be performed regarding the mechanism of action.
“The market will be driven by the increasing use of innovative technology. For instance, the extensive uses of dielectric barrier discharge (DBD) and the non-equilibrium atmospheric pressure plasma jet (N-APPJ) plasma discharge methods have been very effective in various biomedical applications.” - Chief Researcher, Cold Plasma Product Manufacturer, United States
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Asian Cold Plasma Market Set to Soar
APAC is predicted to experience considerable growth in the future years, due to the adoption of technologically advanced cold plasma products in the healthcare industry, increasing demand for decontaminated frozen food, and growing manufacturing of semiconductor, textile, and polymer industries in this region. The development in the European region market is attributed to increasing research and development activities, the availability of various FDA-approved products, and the presence of some of the key players in this region.
Companies Adopt Both Organic & Inorganic Growth Strategies to Increase their Market Share
Players operating in global cold plasma market are accepting organic and inorganic growth strategies such as collaborations, acquisitions, and new product launches to gather market share.
For instance,
In October 2021, Plasmacure secured a new series of funding from a consortium with Topfonds Gelderland, NextGen Ventures, European Innovation Council (EIC) Fund, and Credenti B.V. (a group of informal investors) to carry out clinical studies and to sell their product internationally
In October 2021, Reylon Plasma announced the launch of its compact integration solution piezobrush ® PZ3-I in Bondexpo trade fair preview. The compact integration solution is suitable for a wide variety of surface applications
Competitive Landscape Analysis of Cold Plasma Market
Some of the key players operating in the global cold plasma market include Apyx Medical Corporation, Nordson Corporation, P2i, and Relyon Plasma GmbH, among others.
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Global Cold Plasma Market is anticipated to witness a lucrative CAGR of 16% by 2026 - Increasing Utilization of Cold Plasma in Wound Healing
Cold plasma, the fourth state of matter is a partially ionized gas comprising ions, electrons, ultraviolet photons, and reactive neutrals such as radicals, excited and ground-state molecules. Plasmas can also be artificially generated through gas dissociation by electricity, microwave radiation, or heat under ambient conditions. Due to the low heat capacity of cold plasma, it finds application in bioengineering, medicine, and therapeutics.
Adoption of Cold Atmospheric Plasma Therapy in Wound Healing-
Cold atmospheric plasma therapy is a new and latest approach in the field of plasma medicine. It consists of a mixture of reactive species that convey antimicrobial activity and affect human tissues. Owing to its environment-friendly and non-invasive nature, this technique has been admired and encouraged to use in different therapeutic regimes like wound healing, tissue regeneration, and skin infection management. Atmospheric pressure cold plasmas could affect different stages of wound healing by helping to activate microorganisms in the first stage and stimulate skin-related cell proliferation and migration in the following period.
Cold Plasma Utilization in Dentistry and Oncology
Cold (non-thermal) plasma treatment can be used to prevent or eliminate infections from bacteria, bacterial biofilms, fungi, and viruses. Prospects of cold plasma in dentistry and oncology look promising due to its anti-microbial properties and its cell death properties on cells. In dentistry, cold plasma showed promising results in tooth bleaching, deactivation of biofilms in teeth, instrument sterilization, and composite restoration. Promising findings obtained from in vivo and in vitro studies of cold plasma in oncology show that it will find its niche in the treatment of cancer patients in the future. However, more studies need to be performed regarding the mechanism of action.
“Growing usage of advanced technologies will drive the market. For instance, the extensive uses of dielectric barrier discharge (DBD) and the non-equilibrium atmospheric pressure plasma jet (N-APPJ) plasma discharge methods have been very effective in various biomedical applications.” - Chief Researcher, Cold Plasma Product Manufacturer, United States
Geographic Overview: Asian Cold Plasma Market Set to Soar
APAC cold plasma market is expected to witness a strong growth in the coming years, due to the adoption of technologically advanced cold plasma products in the healthcare industry, rising demand for decontaminated frozen food, and increasing manufacturing of semiconductor, textile, and polymer industries in this region. The growth in the European region market is attributed to increasing research and development activities, the availability of various FDA-approved products, and the presence of some of the top players in this region.
Competitive Landscape Analysis: Global Cold Plasma Market
Some of the established players operating in the cold plasma market are Apyx Medical Corporation, Nordson Corporation, P2i, and Relyon Plasma GmbH, among others.
Companies Adopt Reliable Growth Strategies to Increase their Market Share in Cold Plasma Market
Players operating in the cold plasma market are adopting organic and inorganic growth strategies such as collaborations, acquisitions, and new product launches to garner a higher market share. For instance,
In October 2021, Plasmacure secured a new series of funding from a consortium with Topfonds Gelderland, NextGen Ventures, European Innovation Council (EIC) Fund, and Credenti B.V. (a group of informal investors) to carry out clinical studies and to sell their product internationally.
Get Detailed Insights on Cold Plasma Market Report with TOC @ https://meditechinsights.com/cold-plasma-market/
#cold plasma market#cold plasma#cold plasma market size#global cold plasma market#cold plasma market Share#cold plasma market demand#cold plasma market growth#cold plasma market trend#cold plasma market application
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Erythrobic Acid Market Trends and Dynamic Demand by 2028
Market Outlook
Erythrobic acid is a stereoisomer of ascorbic acid (vitamin C). The use of erythrobic acid as a food preservative has increased after the ban on the use of sulfites as food preservatives by U.S. Food and Drug Administration. Erythrobic acid has various applications into food & beverage industry, pharmaceutical and cosmetics.
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Erythrobic acid is considered as an important antioxidant in the pharmaceutical industry. As an antioxidant erythrobic acid is also used into various products of food and beverage industry such as meat and fish food, frozen vegetable, pickles, fruit juice, syrup, beer, and others. In the cosmetic industry, erythrobic acid is mainly used in hair care and nail care products. Erythrobic acid is also used as oxygen absorbers in bakery products and confectionery.
Without any side effects, erythrobic acid is known to increase the shelf life of food. The market for erythrobic acid is expected to increase during the forecast period due to increasing demand for use of natural preservative into food and beverage industry.
Increasing Demand of Erythrobic Acid in Food & Beverages, Pharmaceutical and Cosmetic Industry
Erythrobic acid is being used as preservatives, color fixative, nutrient supplements in various food products, beverages, frozen items, dairy-based drinks, breakfast cereals, spreads, artificial sweeteners, and vinegar. Erythrobic acid is also used as a water-soluble antioxidant to prevent food color changes caused by oxidation and is also useful to keep the natural flavor and original food color.
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Erythrobic acid is used as acidity regulators into pharmaceuticals and is also used as antioxidant in cosmetics and personal care products. It is extensively used as an ingredient in various in hair care products. The market of erythrobic acid is expected to increase due to the increase in demand for natural ingredients in the food and beverage industry.
Changes in lifestyle along with increasing knowledge and awareness of food safety are turning consumers to natural and organic products. Bound to these factors and applications the market for erythrobic acid is expected to grow into the forecast period.
Erythrobic Acid Market Segmentation
On the basis of end use, the erythrobic acid market is segmented as-
Food Industry & Beverages
Bakery Items
Frozen Food
Breakfast Cereals
Canned & Frozen Food
Processed Meat
Soft drinks
Beer
Wine
Vinegars
Cosmetics and Personal care
Hair Care
Nail Care
Oral Care
Skin Care
Animal feed & Pet Food Industry
Chemical Industry
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On the basis of grade, the erythrobic acid is segmented as-
Food Grade
Pharmaceutical Grade
On the basis of distribution channel, the erythrobic acid is segmented as-
Direct
Indirect
Drug store
Online
Erythrobic Acid Market: Key players
The key players operating in the erythrobic acid market are Redox Pty ltd., Finoric Llc, Newseed Chemical Co., Ltd., Zhengzhou Tuoyang Industry Company Ltd., Fooding group Ltd., Zhucheng Huayuan Bioengineering Co., Ltd, Wuhan Dahua Weiye Pharmaceutical Chemicals Co. Ltd., AquaChem (Yancheng) Industry Co. Ltd., Xi’an Rainbow Bio-Tech co. Ltd., APAC Chemical Corporation, Merck & Co.
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Due to increasing demand for natural preservative regional players are expected to enter in the market and is expected to make the market more competitive, resulting in scale-up of the erythrobic acid market over the forecast period.a
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Acellular Skin Substitutes Market Emerging Factors, Future Demands, and Key Players
Global Acellular Skin Substitutes Market: Overview
Tissue engineered skin substitutes or artificial skin substitutes can be defined as bioengineered skin substitutes derived from human tissue, non-human tissue, synthetic materials, and composite of these materials. These are mostly used in the treatment of burns, diabetic ulcers, vascular ulcers, and lacerations. Acellular skin substitutes are collagen-rich matrices prepared by removing the cellular components (protein and collagen matrix) of human cadaver skin.
Rise in preference for acellular skin substitutes for implant-based skin surgery accelerates the growth of the global acellular skin substitutes market. The American Society of Plastic Surgeons (2012) stated that more than 50% surgeons in the U.S. preferred acellular matrix for skin surgeries. Moreover, rapid rise in the incidence rate of skin disorders across the globe is likely lead to an increased number of patients who will undergo either invasive or non-invasive skin surgeries. According to the American Academy of Dermatology (2013), one in five persons in the U.S. is expected to develop skin disorder in his/her lifetime.
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Global Acellular Skin Substitutes Market: Drivers and Restraints
Acellular skin substitutes are widely utilized for most of the chronic skin disorders across the globe. Hence, rapidly increasing skin disorders is expected to boost global demand for acellular skin substitutes. Availability of up-to-date treatment facilities, skilled doctors and consultants, low cost of treatments in countries such as India, Thailand, Malaysia, and Singapore propel the medical tourism industry. This in turn results in the growth of the global acellular skin substitutes market. Currently available skin surgeries are mostly invasive and require extended healing time and treatment cost. New products and services present large opportunities as the market consists of established players and their brands, but lacks minimally invasive skin surgeries and highly efficient products. Safety and efficacy are the major concerns in the acellular skin substitutes market. Hence, introduction of new products offer an opportunity to enter and establish business in the market. Therefore, focus on low cost and minimally invasive acellular skin substitutes products and procedures is likely to help manufacturers to record high growth in revenue and market share.
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Global Acellular Skin Substitutes Market: Key Segments
The global acellular skin substitutes market can be segmented based on source of cells, application, and region. In terms of source of cells, the global market can be categorized into animal and human. Products derived from animal sources are developed by harvesting living tissue from various donor animals such as bovine, equine, and porcine. Products derived from animal cells include Unite BioMatrix Collagen Wound Dressing, Synovis, and INTEGRA. Allografts are products derived from human cadaver skin. Products derived from human cells include AlloDerm and GraftJacket. Based on application, the global acellular skin substitutes market can be divided into diabetic foot ulcers, lower extremity venous ulcers, ulcers of mixed etiology, pressure ulcers, and plastic surgeries. Appropriate treatment using acellular matrix in various skin diseases results in faster healing.
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Geographically, the global acellular skin substitutes market can be segmented into five major regions: North America, Europe, Asia Pacific, Latin America, and Rest of the World. North America holds the largest share of the global acellular skin substitutes market, followed by Europe. The dominance of these two regions is attributed to increase in prevalence of vascular diseases and rise in demand for skin substitutes. The regions are likely to continue to dominate the global acellular skin substitutes market during the forecast period due to rise in number of injuries and increase in awareness among people. Aging population is a major concern in Europe. The geriatric population is more prone to venous diseases due to reduced immunity and longer stay in hospitals since the wound healing process is slow in elderly people. The European Commission (Eurostat) has estimated that the geriatric population in Europe is expected to reach 525 million by 2035. Hence, rise in the geriatric population is projected to boost demand for acellular skin substitutes in Europe.
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Global Acellular Skin Substitutes Market: Key Players
Key players in the global acellular skin substitutes market include Acelity L.P., Inc., Integra LifeSciences Corporation, and Smith & Nephew plc.
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Europe Platelet-rich Plasma Market Analysis (2020-2027)
Autologous platelet-rich plasma (PRP) is a blood plasma concentrate enriched with platelet count above the baseline of whole blood prepared from patient’s own blood. It is used to accelerate the healing of injured tendons, ligaments, muscles and joints.
Europe platelet-rich plasma market is estimated to account for US$ 75.8 Mn in terms of value by the end of 2027.
Europe Platelet-rich Plasma Market: Drivers
Increasing prevalence of musculoskeletal injuries is expected to boost growth of Europe platelet-rich plasma market over the forecast period. For instance, according to the Study, ‘Prevalence of Musculoskeletal Injuries, Pain, and Illnesses in Elite Female Basketball Players, in Europe, in June 2019, the most frequently injured body parts were lower limbs: more than 60%, representing an injury rate of 0.14 per athletes and a 0.2 pain rate per athlete (during the study period).
Moreover, increasing geriatric population and high adoption of knee osteoarthritis treatment in by the age group is also expected to aid in growth of the market. Aging contributes to soft tissue degeneration and related-disorders, particularly of the knee. For instance, according to the study ���Osteoarthritis in Europe: Impact on health status, work productivity and use of pharmacotherapies in five European countries’ that examined the impact of peripheral joint osteoarthritis across five European countries, UK (43.6%), France, (25.6%), Germany, (15.2%), Spain, (8.4%), and Italy (7.1%) recorded high prevalence of peripheral joint osteoarthritis, with majority of cases aging 55-74 years.
U.K. held dominant position Europe platelet-rich plasma market in 2019, accounting for 23.5% share in terms of valuee, followed by France.
Figure 1. Europe Platelet-rich Plasma Market Value (US$ Mn), by Country/Region, 2019
Europe Platelet-rich Plasma Market: Restraints
Lack of standardization in preparation and dosage of autologous blood concentrate and platelet-separation techniques is a major factor hindering growth of market. Lack of standardization in preparation and dosage of autologous blood concentrate and platelet-separation techniques lead in uncertainty about the evidence to support the increasing clinical use of platelet-rich plasma therapy as a treatment modality for musculoskeletal injuries, including orthopedic bone and soft-tissue injuries.
Moreover, uncertainty about therapeutic efficacy of platelet-rich plasma is also expected to hamper growth of the market. For instance, the study ‘Current Clinical Recommendations for Use of Platelet-Rich Plasma’ published in Current Reviews in Musculoskeletal Medicine in 2018, found moderate high-quality evidence that supported the use of leukocyte-rich (LR)-PRP injection for patellar tendinopathy and of PRP injection for plantar fasciitis and donor site pain in patellar tendon graft Bone-patellar tendon-bone anterior cruciate ligament reconstruction. Moreover, the review also noted insufficient evidence to routinely recommend PRP for rotator cuff tendinopathy, osteoarthritis of the hip, or high ankle sprains.
Europe Platelet-rich Plasma Market: Opportunities
Increasing adoption of PRP in skeletal muscle injuries is expected to offer lucrative growth opportunities for players in the market. PRP has promotes muscle recovery via anabolic growth factors released from activated platelets. This in turn reduces pain, swelling, and time for recovery in skeletal muscle injuries.
Moreover, technological advancements in PRP such as changes in production protocol (time and RPM/centrifugal force) and output level (volume and concentration above baseline) are also expected to aid in growth of the market.
Kits segment in Europe platelet-rich plasma market was valued at US$ 34.9 Mn in 2019 and is expected to reach US$ 60.4 by 2027 at a CAGR of 7.1% during the forecast period.
Market Trends/Key Takeaways
The demand for pure PRP fibrin therapy has increased significantly in the recent past, especially for the treatment of skin wound ulcers and in oral and maxillofacial surgeries. The platelet-rich fibrin therapy is classified as a second generation platelet concentrate, with rich platelet content and extensive growth factors in the form of fibrin membranes, which are free of any anti-coagulants or other artificial bio-chemical modifications and promote rapid and accelerated wound healing.
Increasing geriatric population in Europe has led to high demand for non-invasive or minimally invasive surgical treatments. PRP therapy is a simple, efficient, and minimally invasive procedure that represents an appropriate biological approach for ensuring tissue regeneration in a very short period of time. Such scenario has led to high adoption of PRP therapy for the treatment of orthopedic related injuries in geriatric patients.
Regulations
Europe
· Directive 2002/98/EC of the European Parliament and Council of January 27, 2003, regulates the approval process for blood and blood-derived products
o This committee is engaged in the establishment of quality, safety, and efficacy of blood products and in setting norms for collection, processing, and distribution of blood components across the European Union countries
· Harmonized regulatory framework for PRP therapies is not present
o Each country has its own approach to PRP regulation within the jurisdiction of national authorities
· Devices must comply with Class II- medical device directive 93/42/EEC.
o Device approval is overseen in each EU country by a governmental body called a ‘Competent Authority.’
o The surgical use of PRP can be considered as an autologous graft within the surgical procedure as regulated by Directive 2004/23/EC
Europe Platelet-rich Plasma Market: Competitive Landscape
Major players operating in Europe include, Arthrex, Inc., Stryker Corporation, Johnson and Johnsons Ltd., Zimmer Biomet Holdings Inc., Terumo Corporation, Glofinn Oy, Medira Ltd., Regen Lab S.A., and Estar Technologies Ltd.
Europe Platelet-rich Plasma Market: Key Developments
In January 2020, SHVI PRP Therapy, announced a new website that is focused specifically at the use of PRP to mitigate hair loss.
In March 2019, CollPlant, a regenerative medicine company, renewed its exclusive distribution agreement with Arthrex for Vergenix STR, an injectable gel comprised of cross-linked bioengineered recombinant human type I collagen, rhCollagen, combined with autologous PRP, for the treatment of tendinopathy.
In January 2019, Generex Biotechnology Corporation entered into a letter of intent to acquire Medisource Partners, an FDA-registered distributor of medical and surgical products including supplies kits to process bone marrow aspirates and PRP biologics at the time of surgery.
In December 2018, Regenexx’s research published in the Journal of Translational Medicine, which involved use of patients' own bone marrow concentrate and PRP products demonstrated positive clinical outcomes for the treatment of osteoarthritis of the knee.
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EUROPE PLATELET-RICH PLASMA MARKET ANALYSIS
Autologous platelet-rich plasma (PRP) is a blood plasma concentrate enriched with platelet count above the baseline of whole blood prepared from patient’s own blood. It is used to accelerate the healing of injured tendons, ligaments, muscles and joints.
Europe platelet-rich plasma market is estimated to account for US$ 75.8 Mn in terms of value by the end of 2027.
Europe Platelet-rich Plasma Market: Drivers
Increasing prevalence of musculoskeletal injuries is expected to boost growth of Europe platelet-rich plasma market over the forecast period. For instance, according to the Study, ‘Prevalence of Musculoskeletal Injuries, Pain, and Illnesses in Elite Female Basketball Players, in Europe, in June 2019, the most frequently injured body parts were lower limbs: more than 60%, representing an injury rate of 0.14 per athletes and a 0.2 pain rate per athlete (during the study period).
Moreover, increasing geriatric population and high adoption of knee osteoarthritis treatment in by the age group is also expected to aid in growth of the market. Aging contributes to soft tissue degeneration and related-disorders, particularly of the knee. For instance, according to the study ‘Osteoarthritis in Europe: Impact on health status, work productivity and use of pharmacotherapies in five European countries’ that examined the impact of peripheral joint osteoarthritis across five European countries, UK (43.6%), France, (25.6%), Germany, (15.2%), Spain, (8.4%), and Italy (7.1%) recorded high prevalence of peripheral joint osteoarthritis, with majority of cases aging 55-74 years.
U.K. held dominant position Europe platelet-rich plasma market in 2019, accounting for 23.5% share in terms of valuee, followed by France.
Figure 1. Europe Platelet-rich Plasma Market Value (US$ Mn), by Country/Region, 2019
Europe Platelet-rich Plasma Market: Restraints
Lack of standardization in preparation and dosage of autologous blood concentrate and platelet-separation techniques is a major factor hindering growth of market. Lack of standardization in preparation and dosage of autologous blood concentrate and platelet-separation techniques lead in uncertainty about the evidence to support the increasing clinical use of platelet-rich plasma therapy as a treatment modality for musculoskeletal injuries, including orthopedic bone and soft-tissue injuries.
Moreover, uncertainty about therapeutic efficacy of platelet-rich plasma is also expected to hamper growth of the market. For instance, the study ‘Current Clinical Recommendations for Use of Platelet-Rich Plasma’ published in Current Reviews in Musculoskeletal Medicine in 2018, found moderate high-quality evidence that supported the use of leukocyte-rich (LR)-PRP injection for patellar tendinopathy and of PRP injection for plantar fasciitis and donor site pain in patellar tendon graft Bone-patellar tendon-bone anterior cruciate ligament reconstruction. Moreover, the review also noted insufficient evidence to routinely recommend PRP for rotator cuff tendinopathy, osteoarthritis of the hip, or high ankle sprains.
Europe Platelet-rich Plasma Market: Opportunities
Increasing adoption of PRP in skeletal muscle injuries is expected to offer lucrative growth opportunities for players in the market. PRP has promotes muscle recovery via anabolic growth factors released from activated platelets. This in turn reduces pain, swelling, and time for recovery in skeletal muscle injuries.
Moreover, technological advancements in PRP such as changes in production protocol (time and RPM/centrifugal force) and output level (volume and concentration above baseline) are also expected to aid in growth of the market.
Kits segment in Europe platelet-rich plasma market was valued at US$ 34.9 Mn in 2019 and is expected to reach US$ 60.4 by 2027 at a CAGR of 7.1% during the forecast period.
Market Trends/Key Takeaways
The demand for pure PRP fibrin therapy has increased significantly in the recent past, especially for the treatment of skin wound ulcers and in oral and maxillofacial surgeries. The platelet-rich fibrin therapy is classified as a second generation platelet concentrate, with rich platelet content and extensive growth factors in the form of fibrin membranes, which are free of any anti-coagulants or other artificial bio-chemical modifications and promote rapid and accelerated wound healing.
Increasing geriatric population in Europe has led to high demand for non-invasive or minimally invasive surgical treatments. PRP therapy is a simple, efficient, and minimally invasive procedure that represents an appropriate biological approach for ensuring tissue regeneration in a very short period of time. Such scenario has led to high adoption of PRP therapy for the treatment of orthopedic related injuries in geriatric patients.
Regulations
Europe
Directive 2002/98/EC of the European Parliament and Council of January 27, 2003, regulates the approval process for blood and blood-derived products
Harmonized regulatory framework for PRP therapies is not present
Devices must comply with Class II- medical device directive 93/42/EEC.
This committee is engaged in the establishment of quality, safety, and efficacy of blood products and in setting norms for collection, processing, and distribution of blood components across the European Union countries
Each country has its own approach to PRP regulation within the jurisdiction of national authorities
Device approval is overseen in each EU country by a governmental body called a ‘Competent Authority.’
The surgical use of PRP can be considered as an autologous graft within the surgical procedure as regulated by Directive 2004/23/EC
Europe Platelet-rich Plasma Market: Competitive Landscape
Major players operating in Europe include, Arthrex, Inc., Stryker Corporation, Johnson and Johnsons Ltd., Zimmer Biomet Holdings Inc., Terumo Corporation, Glofinn Oy, Medira Ltd., Regen Lab S.A., and Estar Technologies Ltd.
Europe Platelet-rich Plasma Market: Key Developments
In January 2020, SHVI PRP Therapy, announced a new website that is focused specifically at the use of PRP to mitigate hair loss.
In March 2019, CollPlant, a regenerative medicine company, renewed its exclusive distribution agreement with Arthrex for Vergenix STR, an injectable gel comprised of cross-linked bioengineered recombinant human type I collagen, rhCollagen, combined with autologous PRP, for the treatment of tendinopathy.
In January 2019, Generex Biotechnology Corporation entered into a letter of intent to acquire Medisource Partners, an FDA-registered distributor of medical and surgical products including supplies kits to process bone marrow aspirates and PRP biologics at the time of surgery.
In December 2018, Regenexx’s research published in the Journal of Translational Medicine, which involved use of patients' own bone marrow concentrate and PRP products demonstrated positive clinical outcomes for the treatment of osteoarthritis of the knee.
About Us- Coherent Market Insights is a global market intelligence and consulting organization focused on assisting our plethora of clients achieve transformational growth by helping them make critical business decisions. What we provide: Customized Market Research Services Industry Analysis Services Business Consulting Services Market Intelligence Services Long term Engagement Model Country Specific Analysis Mr. Shah
Coherent Market Insights Pvt.Ltd. Address: 1001 4th Ave, #3200 Seattle, WA 98154, U.S. Phone: +1–206–701–6702 Email: [email protected]
#EUROPE PLATELET-RICH PLASMA MARKET ANALYSIS#platelet-rich plasma#platelet-rich plasma market analysis#europe market analysis
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Nanotechnology Market Material Type, Application and End-User Industry - Global Opportunity Analysis and Industry Forecast 2024
5 July 2019 - The Global Nanotechnology Market is subject to witness a substantial growth at a CAGR of around 17% due to the soaring demand from different industry verticals such as aerospace sector, automobile industry, electronics & electrical sector, pharmaceutical industry, and military & defense sector. Use of nanotechnology offers product security and anti-counterfeiting due to their unique properties such as high magnetic, optical strength, catalytic and electronic properties. Globally, the market is predicted to generate massive revenue over the next seven years, providing numerous opportunities for market players to invest for research and development in the nanotechnology market.
Vast set of application of nanotechnology involving dispersions and coating, consolidated materials, bio-medical and electromechanical devices are expected to offer lucrative growth opportunities for industry players in the upcoming years. Advent of nanomaterials such as graphene and nano-cellulose are predicted to drive growth of market over the forecast period. These nanomaterials are economically viable and possess advanced properties. The constant requirement of nanoparticles such as the gold nanoparticles for technological transformation of healthcare industry is driving the market growth in forecast period. Besides, the large investment from private sector for development of nanotechnology and numerous initiatives from governments are multiplying the progress of the nanotechnology market.
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Increasing adoption of nanotechnology for production of metal nanoparticles, which are broadly consumed in biomedical sciences and bioengineering is expected to boost market growth in the near future. The nanoparticles have become major attraction due to their significant potential for development of nanotechnology in the healthcare industry.
In recent times, metal nanoparticles are synthesized and altered along with different bio-chemical functional groups. This allows metal nanoparticles to conjugate with anti-bodies, ligands, and medicine. Due to these vast functionalities, allows a broad range of possible applications in biotechnology, magnetic severance, pre-concentration of required analysts, targeted medicine distribution, and transportation for gene and medicine delivery. The various metal nanoparticles also allow diagnostic imaging used in biotechnology.
Some of the extensive applications of nanotechnology in different industry verticals include automobile industry, electronics & electrical sector, pharmaceutical industry, military & defense sector, consumer goods, electronics, filtration, and life sciences, which are also expected to contribute positively to market expansion. Introduction of Nano cellulose technology, which gaining widespread popularity in applications such as scaffolds in tissue engineering, artificial skin and cartilage, wound healing and vessel substitutes, and biodegradable food packaging, are estimated to boost market growth over the next seven years.
The market is broadly categorized into major segments based on the product type such as nanomaterials, nano-tools, and nano-devices. The nanomaterials is considered as one of the fastest growing segment in the market with substantial revenue generation in the last few years. Growing popularity of the segment is attributed to the increasing demand form electronics industry, power & energy sector and defense industry. The nano-devices segment has also witnessed substantial growth owing to the increasing adoption in the electromechanical devices.
The market is divided by region as North America, Europe, Asia-Pacific, Latin America and Africa. North America has shown major growth in recent years owing to the rise in the implementation of latest technologies in electronic sector, increase in the number of research & development activities, and existence of well-established industrial infrastructure in the region.
Asia-Pacific region is predicted to hold major market share in the nanotechnology market with massive growth in forecast period. Countries such as South Korea, China and Japan are leading the Asia-Pacific market with increasing consummation of highest consumption of the metal nanoparticles and significant investment by leading industry players considering potential growth opportunities in the region.
The key players in the nanotechnology market are Altair Nanotechnologies Inc., AMCOL International Co., BioDelivery Sciences International Inc., Clariant International Ltd., Competitive Technologies Inc., Dendritic NanoTechnologies, Inc., Eastman Kodak Co., Frontier Carbon Co., Hosokawa Micron Group AG, and Hyperion Catalysis International, Inc.
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Bioengineered Artificial Skin is Estimated to Witness High Growth Owing to Opportunity to Treat Burn Injuries
Bioengineered artificial skin, also known as bioengineered skin substitutes, are used as temporary wound cover for burn patients until sufficient skin grows back or a skin transplant can be performed. Bioengineered artificial skin acts as an impressive barrier against infections and fluid loss for severely burned patients. It is biodegradable and allows patient's own cells to gradually populate and replace it.
The global Bioengineered Artificial Skin Market is estimated to be valued at US$ 510 million in 2023 and is expected to exhibit a CAGR of 16.% over the forecast period 2023 to 2032, as highlighted in a new report published by Coherent Market Insights. Market Opportunity: According to the World Health Organization (WHO), burn injuries account for over 180,000 deaths worldwide every year. With increasing cases of burn injuries due to industrial and fire accidents, the demand for bioengineered artificial skin is increasing significantly. As bioengineered artificial skin assists in effective treatment of burn wounds and reducing fatalities associated with severe burns, the rising incidence burn injuries present a lucrative market opportunity for growth of the bioengineered artificial skin market over the forecast period. Bioengineered artificial skin substitutes efficiently treat burn injuries and expedite healing process without risk of disease transmission or rejection, which helps save lives and reduces healthcare costs associated with long treatment of severe burn injuries. Porter’s Analysis Threat of new entrants: The threat of new entrants is moderate as the market requires significant R&D investments and manufacturing capabilities to produce bioengineered artificial skin. However, partnership with established players can reduce the entry barriers. Bargaining power of buyers: The bargaining power of buyers is high given the availability of substitute wound healing products. Buyers can negotiate on price and demand additional services. Bargaining power of suppliers: The bargaining power of suppliers is moderate since raw materials for bioengineered artificial skin such as collagen and peptides have few substitutes. Suppliers may charge higher prices. Threat of new substitutes: The threat of new substitutes is high as wound healing alternatives like skin grafts and wound dressing are continuously evolving. Competitive rivalry: The competitive rivalry is high among existing players due to their global presence and new product launches. SWOT Analysis Strength: Rapid adoption in burn treatment and skin grafting, increasing wound care expenditure, growing demand for minimal invasive treatments. Weakness: High costs impact affordability, limited market awareness, long regulatory approval process. Opportunity: Untapped growth potentials in emerging markets, rise in incidence of skin diseases and injuries, partnerships to expand geographical footprints. Threats: Reimbursement issues vary globally, entry of local generic substitutes, complications associated with wound healing process. Key Takeaways The global Bioengineered Artificial Skin Market is expected to witness high growth during the forecast period 2023 to 2028. Regional analysis: In the Asia Pacific, countries like India, China and Japan are expected to be the fastest growing regional markets due to continuously evolving healthcare infrastructure, rising medical tourism, growing obesity rates and diabetic population. Key players: Key players operating in the Bioengineered Artificial Skin market are Smith & Nephew, MiMedx, Organogenesis, Integra LifeSciences, Tissue Regenix and Mylan. Smith & Nephew offers skin substitute products like Dermagraft and Orcel while Organogenesis provides wound care products like Apligraf and Gintgraft.
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Cell Expansion Market 2026 Size, Share, Trends, Growth, Regional Outlook And Forecast to 2026
Cell expansion is the large scale artificial production of daughter cells from a single cell, to support medical research. Rising preference for regenerative medicines offering faster results, and emergence of cell-based therapies with high patient compatibility are expected to fuel the cell expansion market during the forecast period (2017–2025). Regenerative medicine helps the body to form new functional tissue to replace defective or lost ones providing treatment for conditions with inadequate therapies. According to the U.S. Department of Health and Services, in 2016, NIH invested around US$ 1.5 billion in stem cell research projects. Increasing government and private sector expenditure on cell-based research therapies is expected to boost growth of the market for cell expansion in the near future. The number of FDA approvals for clinical trials of stem cell-based treatments is rapidly increasing. According to a report published by Pharmaceutical Research and Manufacturers of America, in 2013, around 69 cell therapies with clinical trials were under review with the FDA. The therapeutic classes represented in these trials include skin diseases, cardiovascular diseases, transplantations, eye conditions, cancer and associated conditions, musculoskeletal disorders, genetic disorders, and digestive disorders.
Increasing incidence of chronic medical conditions is expected to boost growth of the cell expansion market over the forecast period
The increasing cases of chronic and rare medical conditions around the world is another key factor driving demand for cell expansion. For instance, according to World Health Organization (WHO), around 15 million people are projected to suffer from cancer by 2020. The rising prevalence of cancer, is in turn, expected to boost growth of the cell expansion market. Cell-based therapy is also a promising approach for treating chronic kidney disease and is presently the focus of preclinical studies. Recent advancements in regenerative medicine and tissue engineering have created cell-based approaches for the treatment of renal failure. Such treatments include biotechnological approach using implantation of bioengineered kidney constructs, transplanting cells, and bio-artificial renal systems. However, lack of high-tech instrumentation and skilled workforce coupled with the high cost of operations are expected to hamper growth of the cell expansion market.
Market Taxonomy
On the basis of product type, the cell expansion market is segmented into:
Consumables
Reagents, Serum, and Media
Disposables
Equipment
Cell Expansion Supporting Equipment
Flow Cytometer
Cell Counters
Centrifuges
Other Supporting Equipment
Bioreactors
Automated Cell Expansion Systems
On the basis of application, the cell expansion market is segmented into:
Regenerative Medicine and Stem Cell Research
Cancer and Cell-based Research
Others
On the basis of cell type, the cell expansion market is segmented into:
Human Cells
Stem Cells
Adult Stem Cells
Induced Pluripotent Stem Cells
Embryonic Stem Cells
Differentiated Cells
Animal Cells
On the basis of end user, the cell expansion market is segmented into:
Research Institutes
Biopharmaceutical and Biotechnology Companies
Cell Banks
Others
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North America is expected to hold a dominant position in the cell expansion market due to increasing demand for regenerative medicines and rising incidence of chronic diseases
Regional segmentation of the cell expansion market by Coherent Market Insights includes North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. The cell expansion market in North America is driven by the increasing demand for regenerative medicines that are highly compatible with patients and offer rapid results. For instance, the FDA is increasingly approving treatments involving cells derived from bone or blood marrow, due to its well-established efficacy and safety. Furthermore, increasing incidence of chronic diseases and rising R&D investments for the development of cell-based products are other factors expected to support growth of the cell expansion market. According to a study published in NIH report, around 500,000 people benefit from a transplant each year using regenerative medicine in the U.S. Increasing R&D expenditure by several companies for the development of new therapeutic products and availability of untapped growth opportunities are expected to drive the cell expansion market in Asia Pacific. Biotechnology merger and acquisition (M&A) activities have also experienced a boost in the region. According to investment bank China Renaissance, in 2016, 37 pharmaceutical and biotech M&A deals worth US$ 6.8 billion were closed in China.
Major industry players use merger and acquisitions as their major growth strategy
Key players operating in the cell expansion market include Becton, Dickinson and Company, Beckman Coulter, Inc., Corning, Inc., GE Healthcare, Lonza, Merck KGaA (Sigma-Aldrich Co. LLC), Miltenyi Biotec, Thermo Fisher Scientific, Inc., Terumo BCT, Inc., and Stemcell Technologies, Inc. In July 2016, GE Healthcare acquired Biosafe SA, a Swiss company that manufactures instruments that recover stem cells and help in various other cell processing procedures related to personalized medicine. This acquisition will help GE Healthcare to grow the cells in the sample for appropriate dose sizes.
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Nanotechnology Market 2025 is Estimated to Grow at Fastest Rate by Top Key Manufacturers
7 March 2019: Nanotechnology Market is subject to witness a substantial growth at a CAGR of around 17% due to the soaring demand from different industry verticals such as aerospace sector, automobile industry, electronics & electrical sector, pharmaceutical industry, and military & defense sector. Use of nanotechnology offers product security and anti-counterfeiting due to their unique properties such as high magnetic, optical strength, catalytic and electronic properties. Globally, the market is predicted to generate massive revenue over the next seven years, providing numerous opportunities for market players to invest for research and development in the nanotechnology market.
Vast set of application of nanotechnology involving dispersions and coating, consolidated materials, bio-medical and electromechanical devices are expected to offer lucrative growth opportunities for industry players in the upcoming years. Advent of nanomaterials such as graphene and nano-cellulose are predicted to drive growth of market over the forecast period. These nanomaterials are economically viable and possess advanced properties. The constant requirement of nanoparticles such as the gold nanoparticles for technological transformation of healthcare industry is driving the market growth in forecast period. Besides, the large investment from private sector for development of nanotechnology and numerous initiatives from governments are multiplying the progress of the nanotechnology market.
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Increasing adoption of nanotechnology for production of metal nanoparticles, which are broadly consumed in biomedical sciences and bioengineering is expected to boost market growth in the near future. The nanoparticles have become major attraction due to their significant potential for development of nanotechnology in the healthcare industry.
Some of the extensive applications of nanotechnology in different industry verticals include automobile industry, electronics & electrical sector, pharmaceutical industry, military & defense sector, consumer goods, electronics, filtration, and life sciences, which are also expected to contribute positively to market expansion. Introduction of Nano cellulose technology, which gaining widespread popularity in applications such as scaffolds in tissue engineering, artificial skin and cartilage, wound healing and vessel substitutes, and biodegradable food packaging, are estimated to boost market growth over the next seven years.
The key players in the nanotechnology market are Altair Nanotechnologies Inc., AMCOL International Co., BioDelivery Sciences International Inc., Clariant International Ltd., Competitive Technologies Inc., Dendritic NanoTechnologies, Inc., Eastman Kodak Co., Frontier Carbon Co., Hosokawa Micron Group AG, and Hyperion Catalysis International, Inc.
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