#BioDefense

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[didanawisgi]

Biodefense Posture Review

[secretofresearch]

Biodefense: Understanding the Role of Biodefence Against Biological Threats In Industry

Biological threats pose a serious danger to national and global security. Biological agents like viruses, bacteria, toxins and other disease-causing organisms can potentially sicken or kill large numbers of people if used as weapons. Some examples of pathogenic biological agents that have been militarized or have potential as bioweapons include anthrax, plague, smallpox, tularemia and staphylococcal enterotoxin B. These agents are highly dangerous due their ability to sicken or kill on exposure, difficulty of detection and potential transmission between people. Several rogue states and terrorist organizations are suspected to be pursuing offensive biological weapons programs, raising the risk of hostile use or accidental release of dangerous pathogens. The threat of biological weapons has grown in the modern world due to advances in biotechnology which has enabled easier production of biological agents that can potentially be used for hostile purposes. This underscores the importance of biological defense against such threats through early detection, prevention and preparedness measures.

Goals and Objectives of Biodefense

Biological defense involves coordinated efforts across scientific, medical, security and policy domains aimed at addressing biological threats through non-proliferation, countermeasures and response capabilities. The overarching goals of biological defense are to minimize vulnerabilities, detect biological incidents early, mitigate impacts and enable rapid recovery. Specific objectives include developing capabilities for early warning and detection of outbreaks using disease surveillance and biosensors. Biodefense also involves stockpiling effective medical countermeasures like vaccines, antiviral drugs and therapeutic antibodies. Biological defense research contributes to the development of new and improved vaccines, diagnostics, prophylactic and therapeutic agents. Response planning and coordination between healthcare, law enforcement and other stakeholders ensures preparedness for potential biological incidents. International cooperation and treaties seek to prevent the spread and hostile use of pathogens through export controls and verification mechanisms.

Surveillance and Detection Systems

One of the most important components of biological defense is early detection through disease monitoring and biosensors. The United States operates an integrated biosurveillance program involving multiple agencies that provide early warning of disease outbreaks. Systems like the National Syndromic Surveillance Program monitor emergency room visits and pre-hospital care reports for signs of epidemics. Additional programs track influenza-like illnesses and analyze data from Medical Information Surveillance Integrated System, Google Flu Trends and other sources to identify potential outbreaks rapidly. Biodefence agencies are also investing in research to develop advanced nucleic acid, protein and antibody-based biosensors for rapid, sensitive and specific detection of potential biological weapons agents. Some future technologies under development include handheld devices that can detect airborne pathogens as well as systems for continuous, real-time monitoring of public areas such as airports or subways for signs of biological incidents. Early detection is critical to reduce impact because it allows for immediate healthcare mobilization and faster dispensation of medical countermeasures.

Medical Countermeasures Strategies

Biological defense stockpiles form a crucial component of defense by ensuring timely access to antibiotics, antivirals, antitoxins, vaccines and other medical countermeasures in the event of a biological attack. The US Strategic National Stockpile maintains large caches of pharmaceuticals, medical supplies and equipment for rapid response and dispensing after exposure to pathogens. Key medical countermeasures for high-priority biological threats include anthrax vaccines, smallpox vaccines, antiviral drugs for influenza and botulism antitoxins. There is a continuing focus on developing improved countermeasures for emerging and engineered threats as well as combating antimicrobial resistance. For instance, efforts are underway to develop next generation anthrax vaccines with broader effectiveness and fewer doses required. Research is also being conducted to design versatile platform technologies like monoclonal antibody therapies, adjuvant systems and genomic analysis tools to speed up countermeasure development against unknown future threats. International cooperation helps expand countermeasure access globally and strengthens preparedness worldwide against biological incidents.

Response Planning and Preparedness Exercises

Effective biological defense requires coordinated response planning across various levels from federal agencies down to state and local public health networks. Response plans delineate roles, responsibilities and standard operating procedures during potential biological incidents to enable rapid detection, healthcare mobilization, casualty treatment and mitigation efforts. Emergency Operations Centers are equipped and staffed to coordinate large-scale incident management in real-time. Preparedness exercises test response plans, find gaps, improve coordination and train frontline professionals through simulated biological scenarios. Some examples are biennial Crimson Contagion drills conducted by the US Department of Health and Human Services simulating nationwide outbreaks, TOPOFF full-scale exercises simulating complex terrorism incidents, and annual Pandemic Influenza Readiness Exercises focused on healthcare surge capacity. As part of continuity of government planning, agencies have developed detailed contingency plans for sustaining essential services during staff shortages or infrastructure disruptions due to a biological attack. Regular drills at federal, state and community levels help strengthen all-hazards preparedness nationwide.

Challenges and Future Directions

While considerable progress has been made, biological defense efforts still face scientific, technical and policy related challenges. Rapid evolution of microbiological threats requires agility to update detection and response systems. Scientific dilemmas persist with bioforensics, attribution, biotechnology oversight and managing dual-use risks. Costs of upgrading surveillance infrastructure countrywide are high. Stockpiling of multi-purpose medical countermeasures needs accelerated investment while ensuring incentives for industry involvement. Globalisation and interconnectivity necessitate greater international cooperation on biosecurity best practices, export controls and pathogen transparency. Future priorities include developing artificial intelligence assisted analytics, blockchain enabled public health data-sharing, novel diagnostics based on microfluidics, mobile detection laboratories and telemedicine facilities to empower distributed biological defense capabilities

In the face of growing biological risks, a robust biological defense encompassing coordinated preventive mechanisms, preparedness planning and technological solutions provide strategic depth against intentional outbreaks and natural disease emergencies. While continual progress is needed, past investments in early warning systems, medical countermeasures development and coordinated exercises have undoubtedly strengthened resilience of nations. With prudent management of evolving threats and challenges, further optimization of integrated biological defense has the potential to significantly curb impacts from biological incidents in the decades ahead. Global health security also depends on collaborative efforts that foster transparency, reinforce international norms and enable rapid sharing of expertise during public health emergencies. A multilateral approach will be integral to the long term success of this critical mission.

Get more insights on Biodefense

About Author:

Money Singh is a seasoned content writer with over four years of experience in the market research sector. Her expertise spans various industries, including food and beverages, biotechnology, chemical and materials, defense and aerospace, consumer goods, etc. (https://www.linkedin.com/in/money-singh-590844163)

[ourwitching]

[Header image: Photo of the lunar lander taken during Apollo 11.] In 1969, after successfully br...

[faultfalha]

As the darkness slowly gave way to the light of day, a new kind of warfare had emerged in the shadows of a forgotten land. The Chinese had crafted a new means of secretly waging war using a combination of cyber and biological weapons that were beyond the comprehension of the surrounding nations. It was a new kind of fear that left those living in its path in a state of tension. The warfare was so invisible, so hidden, yet so powerful, that no one knew who would be the next target of this unprecedented form of warfare.

[fairfieldmarketreports]

Biodefense Market 2023 Share, Size, Key Players, Revenue Analysis

Biodefense Market Set for Robust Growth, Finds Fairfield Market Research

Fairfield Market Research, a leading market research firm, projects a substantial revenue growth in the UK biodefense market from 2023 to 2030. The market analysis indicates a healthy pace for revenue expansion, driven by increasing prevalence of infectious diseases, mounting demand in the wake of potential bioterrorist attacks, growing geopolitical conflicts, and technological advances and infrastructure developments.

Access Full Report: https://www.fairfieldmarketresearch.com/report/biodefense-market

According to the report, the UK biodefense market is expected to achieve an impressive compound annual growth rate (CAGR) of 6.3% during the assessment period. By 2030, the market size is anticipated to reach a valuation of US$24.5 billion. Anthrax, a leading segment in terms of type, is expected to retain its dominance. Additionally, the military segment is projected to hold the largest share in the biodefense industry by end use, contributing an estimated revenue of US$22.8 billion by 2030.

The report highlights the increasing prevalence of infectious diseases as a key driver for the growth of the biodefense market in the UK. Governments worldwide are expanding their budgets for research and development of biodefense treatments to combat biological threats and potential rogue pathogenic attacks. This emphasis on biodefense is expected to result in an exponential spike in demand for biodefense treatments in the next five years.

The rising threat of bioterrorism, coupled with escalating geopolitical tensions globally, has prompted nations to strengthen their arsenal, which, in turn, is boosting the revenue of the biodefense market. Governments worldwide are ramping up defense budgets and allocating dedicated resources to biological and chemical defense mechanisms. The market is also benefiting from increasing mass awareness regarding the serious implications of biothreats and the growing emphasis on public health services and diagnostics for the detection of biothreat agents.

The UK biodefense market is expected to benefit from technological advancements and infrastructural developments aimed at safeguarding the population. The demand for biodefense countermeasures reflects ongoing concerns about global terrorism and biowarfare. The UK government remains a significant source of development and procurement backing for biopharmaceutical companies and academic institutions involved in biodefense research.

Despite the positive growth prospects, the report also highlights certain challenges faced by the biodefense market. The indeterminate scope, type, and magnitude of future bioweapon attacks create uncertainty in demand for biodefense products. Developers of medical countermeasures are reliant on government purchases, which are subject to shifting political priorities and changing threat assessments. These factors present market uncertainties and limited profit potential, which may hinder commercial investments in biodefense products.

Fairfield Market Research identifies Europe and the Asia Pacific region as promising markets for the biodefense industry. European countries have increased their research and development expenditure in response to the COVID-19 pandemic, while emerging markets in the Asia Pacific region are rapidly catching up in terms of R&D expenditure for vaccine development and manufacturing. Key players in the global biodefense market, including Emergent BioSolutions, Inc., SIGA Technologies, Inc., and Sanofi Pasteur, are actively involved in advanced technology adoption and strategic collaborations to stay competitive.

[fairfieldmarket]

Notable Investments to Intercept Biowarfare Externalities Add Value to Global Biodefense Market’s Robust Growth Outlook

Biodefense refers to the national defense mechanism dealing with biological threats and rogue pathogenic attacks among others. Several economies are pouring significant resources into research and development (R&D) initiatives to safeguard their country against biodefense externalities. The demand for biodefense solutions is expected to increase notably in such circumstances. The cumulative force of these factors is set to strengthen the trajectory of the global biodefense market.

In the aftermath of the global COVID-19 pandemic, several governments and defense organisations have taken biological warfare into consideration. The unprecedented impact on the economy, public health, law and order, and other processes of national importance is becoming the basis for these conversations. Such recent resurgence around the possibilities and projected impact of biological warfare have reinvigorated the conversation around strengthening biodefense.

Notable Digital Health Efforts to Instigate Prolonged Growth Possibilities

The improvements in digital technologies, particularly digital health, are creating novel possibilities for biodefense research. Several cutting-edge prophylactics, diagnostic, and therapeutic biodefense products have gained a market stronghold. Numerous military purposes, civilian protection, and research-oriented biodefense products are emerging. These solutions provide safety against biological, chemical, and radioactive threats and associated infectious diseases. Smallpox, anthrax, botulism, and radiation sickness and exposure are some of the most challenging health conditions spread by biodefense threats.

The global biodefense market is set to exhibit incremental expansion in such a business landscape. The most active players currently spearheading these developments include Emergent BioSolutions, Inc., Bavarian Nordic A/S, Nanotherapeutics, Inc., SIGA Technologies, Inc., GSK plc., Altimmune, Inc., Statera Biopharma, Inc., Sanofi Pasteur, Dynavax Technologies Corporation, Xoma Corporation, Meridian Medical Technologies, LLC, NightHawk Biosciences, Inc., Dynport Vaccine Company LLC, and Soligenix.

Research Efforts by Military End Users to Boost Global Biodefense Market Expansion

The military, civil, and research institutes are the leading end users in the biodefense market. The stakeholders in the military segment are expected to generate the highest revenue in the forecast period with an estimated revenue contribution of US$22.8 Bn by 2030. Meanwhile, civilian end users are also showcasing considerable growth potential.

As for the research institutes, they are focusing on reciprocal threats from emerging/re-emerging infectious diseases alongside accidentally or deliberately released threats. The chemical, biological, radiological, and nuclear (CBRN) agents are the major focus area of these research efforts owing to their high potential public disruption capabilities.

Unwavering Biodefense Efforts Across North America to Facilitate Steep Growth Curve

As one of the leading defense industries, North America is expected to emerge as the leading biodefense market region. The biodefense department in major economies such as the USA is the leading contributor to this trend. The nation scores a very high index score in Global Health Security (GHS) metric showcasing its preparedness against biodefense threats. The combined effort by these economies’ governments, militaries, and healthcare/biotech industry stakeholders are generating such promising outcomes. Elsewhere, countries in Europe and Asia Pacific are also taking stern biodefense steps in the wake of the COVID-19 pandemic.

The global biodefense market is thriving at a fast pace, growing from its US$14.8 Bn valuation in 2022 to an impressive market size of US$24.5 Bn in 2030. Fairfield Market Research also notes that this impressive growth trajectory will materialize at a CAGR of 6.3% between the 2023-2030 forecast period.

Access Full Report: https://www.fairfieldmarketresearch.com/report/biodefense-market

About Us

Fairfield Market Research is a UK-based market research provider. Fairfield offers a wide spectrum of services, ranging from customized reports to consulting solutions. With a strong European footprint, Fairfield operates globally and helps businesses navigate through business cycles, with quick responses and multi-pronged approaches. The company values an eye for insightful take on global matters, ably backed by a team of exceptionally experienced researchers. With a strong repository of syndicated market research reports that are continuously published & updated to ensure the ever-changing needs of customers are met with absolute promptness.

ContactFairfield Market Research London, UK UK +44 (0)20 30025888    USA (Toll-free) +1 (844) 3829746  Web: https://www.fairfieldmarketresearch.com/ Email: sales@fairfieldmarketresearch.com Twitter: https://twitter.com/FairfieldMarket LinkedIn: https://www.linkedin.com/company/fairfield-market-research-uk

[carolyn-sittingat-jesusfeet]

The Waiting-For-Pandemic Transhuman Cult of Biodefense

"The Transhuman quest for genetic modification in order to change the human condition will end in total disaster. “Hacking the human body” is a myth perpetuated by academics like Yuval Noah Harari and Klaus Schwab with his Fourth Industrial Revolution narrative. Globally, however, biodefense spending is in the trillions and shows no signs of restraint." TN Editor

https://www.technocracy.news/the-waiting-for-pandemic-transhuman-cult-of-biodefense/

[thejjchandler]

(Bipartisan Commission on Biodefense)

[soumyafwr]

https://biiut.com/read-blog/72121_biodefense-market-size-analysis-and-forecast-2031.html

Biodefense Market Size, Analysis and Forecast 2031

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[postoctobrist]

literally in a grad school biodefense course and an assignment is finding a way to kill james bond with any natural toxin (can't be ricin or tetrodotoxin; it's been done) and i'm just staring at the grading rubric going "nova would love this"

well obviously you can’t use any animal for this because Bond will beat it to death with his shoe. poisoning his martini with IIRC digitalis was very effective in Casino Royale, albeit he was able to access some very effective telemedicine. so you want something that’s going to incapacitate an athletic (if seriously alcoholic) man very quickly. I think the weakness to play on here is women. Bond loves creepily touching a woman, so I wonder if you get some kind of transdermal poisoning going on there somehow, do him Kim Jong-nam style. Fuck I’m going to be thinking about this all day

[covid-safer-hotties]

Kids Are Headed Back to School. Are They Breathing Clean Air? - Published Sept 3, 2024

Across the U.S., kids are headed back to their classrooms—just as COVID nears a fresh, late-summer peak. Somehow, four years into a viral pandemic that everyone now knows spreads through the air, most schools have done little to nothing to make sure their students will breathe safely.

We—and especially our children—should be able to walk into a store or a gym or a school and assume the air is clean to breathe. Like water from the faucet, regulations should ensure our air is safe. “Air is tricky. You can choose to not partake of the water or the snacks on the table, but you can’t just abstain from breathing,” notes Gigi Gronvall, senior scholar at the Johns Hopkins Center for Health Security and an author of a 2021 report on the benefits of improving ventilation in schools.

The COVID-causing virus SARS-CoV-2 is far from the only airborne risk in schools. There are also other respiratory viruses, smoke from wildfires, mold spores, off-gassing from plastics and other compounds, air pollution from traffic and industry, and allergens that worsen asthma and add to sick days. Yet federal air standards are stuck in the 1970s, when they were mostly aimed at protecting people from secondhand tobacco smoke, says Joseph Allen, director of the Healthy Buildings Program at the Harvard T. H. Chan School of Public Health. Fully updated standards for buildings are years or even decades away.

It’s hard to assess just what schools have or haven’t done to improve indoor air quality. No one—not one federal agency—collects nationwide air quality data on individual schools. Schools could use federal money to update air filtration and ventilation during the height of the pandemic. But a 2022 Centers for Disease Control and Prevention survey of school districts found that only half had taken simple steps such as opening windows or doors or using fans, and even fewer had upgraded ventilation systems.

The benefits go beyond protecting children and adults alike from airborne disease spread. “Better ventilation is linked with better test scores and grades [and] better workplace performance,” Allen said at a July meeting about air quality held by the Bipartisan Commission on Biodefense, a U.S. think tank.

“We have made incredible gains related to food safety, sanitation and water quality. Where is air quality in this?” he asked. “We have ignored it.” The CDC and the Food and Drug Administration quickly warn people about listeria in sliced meat or lead in cinnamon, but no one’s checking the air in public buildings for disease-causing germs.

It’s not even hard to make sure indoor air is clean. Even in the 1800s, by having open doors and windows, tuberculosis sanatoriums prevented the spread of disease by air. The CDC has extensive guidelines on what’s known as air exchange, but ultimately, it’s a matter of moving contaminated air out and fresh air in.

If it’s too hot, cold, polluted or humid outside, heating, ventilation and air-conditioning (HVAC) systems can clean up the air perfectly well when they are installed properly and used consistently. Their benefits far outweigh their costs.

“There never has been a building that we could not turn into a healthy building with just a little bit of attention,” said Allen, one of the country’s top crusaders for cleaner air, at the biodefense meeting.

Pandemic fatigue, of course, explains much of the apathy around making air-quality improvements. Public officials, from principals to local legislators right up to the top of the federal government, see that hospitals are no longer overflowing with COVID cases and that the nightly news no longer provides daily death counts. Most parents no longer clamor for assurances that their kids are safe from SARS-CoV-2.

Despite regular, ongoing spikes in COVID, most people have dropped precautions such as masks, even in hospitals.

“People are like, ‘There’s not a whole lot you can do about it,’ and that is why, societally, we need to do something about it,” Gronvall says. “We did this for water once upon a time, and we can do it for air.”

Even the experts have mostly let down their guard.

It wasn’t until halfway through the daylong, in-person-only biodefense conference on air quality that someone even thought to ask if the air in the room was safe to breathe. “Are air monitors effective?” asked former U.S. representative Fred Upton, a Republican and a commissioner at the Bipartisan Commission on Biodefense, at the July meeting. “Does anyone here have one?” added Upton, who had represented Michigan’s sixth district until 2023.

“Are you sure you want to know?” someone in the audience asked, prompting laughter. Rick Rasansky, CEO of XCMR Biodefense Solutions, did have a carbon dioxide monitor, a device that gives a very rough estimate of the amount of fresh air exchange in a room. He read out a “pretty good” measurement.

That was a lucky thing because the 100 or so people attending the meeting had been seated shoulder to shoulder for several hours at that point. Not one was wearing a mask.

It will take federal legislation and sustained attention to make a difference.

The Center for Health Security at Johns Hopkins University have developed a Model Clean Indoor Air Act, which state legislatures throughout the country could use in writing new indoor air laws. In Congress, Representatives Paul Tonko of New York State and Brian Fitzpatrick of Pennsylvania have introduced a bipartisan bill that would require the Environmental Protection Agency to list indoor air contaminants and develop guidelines (albeit voluntary ones).

The new federal Advanced Research Projects Agency for Health (ARPA-H) found a great acronym in its Building Resilient Environments for Air and Total Health (BREATHE) program, which will develop and roll out cool new air-cleaning technologies.

But fancy tech isn’t enough on its own, and some schools may have wasted money on glittery toys instead of real fixes. Ceiling-installed ultraviolet lights won’t kill germs if the air isn’t blown upward to get cleaned in the first place. And gadgetry won’t create the demand and enthusiasm needed for cleaner indoor air. Politicians won’t win elections by campaigning on clean indoor air. But once they have been elected, federal, state and local officials owe it to kids, their parents and their neighbors to fight this most invisible of all hazards.

“We need to make it easier for people to see what they can’t see—to see what they’re breathing,” Gronvall says.

Unpaywalled link: archive.is/20240904045601/https://www.scientificamerican.com/article/kids-are-headed-back-to-school-are-they-breathing-clean-air/#selection-499.0-617.111