#Apixaban

[mcatmemoranda]

You have to decrease the dose of Eliquis if pt is less than 60 kg, over 80 y/o, has reduced renal function. A mnemonic is ABCD, Age greater than or equal to 80, Body weight less than or equal to 60 kg, creatinine greater than or equal to 1.5, Double of these factors. Halve dose to 2,5 mg bid.

[medicomunicare]

Bleeding out of the tumor: not only informations, but bad prognosis for patients as well

Cancer and the hemostatic system are tightly interconnected, and a hemostatic imbalance is frequently observed in patients with cancer. Clinical manifestations of this interaction may occur as both thrombotic and bleeding complications. Previous research has predominantly focused on thrombotic issues associated with cancer, such as venous thromboembolism (VTE) and arterial thromboembolic events,…

[janineluciaa]

Order Your (Apixaban) Eliquis Online & Experience the Difference

Learn the suitability of ordering your (Apixaban) Eliquis online and elevate your healthcare experience. With just a few clicks, access a wide range of health product from the comfort of your home. Enjoy swift deliveries, reasonable prices, and the reassurance of quality. Embrace the future of healthcare with seamless online health products services.

[healthcaretechnologynews]

Taking a closer look - Oral Anticoagulants

Oral anticoagulants are utilized in treatment of many cardiovascular indications like NAVF, AF, DVT, PE and stroke.

Warfarin and Apixaban are most recommended treatments and Pfizer, Novartis, Bayer, and Merck are the biggest players in the space. The key considerations that influence therapy choice are efficacy, safety, frequency of monitoring and cost of the drug.

The most important unmet medical needs in the space are gaps in diagnosis and optimizing quick diagnosis, Delays in treatment start due to long waiting time for specialists’ appointment, and low drug adherence.

To address the unmet needs pharma companies, regulatory bodies are undertaking many initiatives including digitalization, implementing AI in diagnosis equipment etc.

Write to us at enquire@grgonline.com to learn how GRG Health is helping clients gather more in-depth market-level information on such topics.

Oral anticoagulant like warfarin, NOACs are utilized in treatment of many cardiovascular indications like NAVF, AF, DVT, PE and stroke. Patients seek medical attention from GPs or Specialist due to pre-existing illness. Most common symptoms of NVAF patients are high blood pressure, Chest pain, irregular heartbeats, and shortness of breath; and most common symptoms of DVT patients are pain, swelling and clot in legs.

For diagnosis the basic tests conducted are ECG, Blood tests, blood pressure tests and ultrasound, as per the set protocol of Hospitals followed by GPs and Specialists. Warfarin and Apixaban are most recommended treatments and Pfizer, Novartis, Bayer, and Merck are the biggest players in the space. The key considerations that influence therapy choice are efficacy, safety, frequency of monitoring and cost of the drug.

We think that the most important unmet medical needs in the space are gaps in diagnosis and optimizing quick diagnosis, Delays in treatment start due to long waiting time for specialists’ appointment, gaps in effective communication between Physicians and Specialists, lack of awareness, lack of manpower, Lack of advanced diagnostic tools, and low drug adherence.

To address the needs regulatory bodies, Pharma companies and patient associations have undertaken many initiatives which involves digitalization (e.g., mobile apps), educating patients via seminars, campaigns and raising awareness at national, regional and local level and implying conventional methods like enhancing effective communication through electronic medium and implementing anti-coagulation alert cards etc.

We think that smooth collaboration between the primary and the secondary care to avoid delay in referral and treatment start, thereby speeding up the process of screening and hence preventing the risk of stroke can be one of the most important futuristic approaches to improve quality of care. Others can be using Application based diagnostic tools or devices or Advanced technology like mobile app, wearables, powerful ultrasounds, X-ray, or body scanners that can improve patient outcomes and patient care management by improving testing, diagnosis, providing quick results and enhancing drug adherence.

Application enabling initial screening of the patients with AF on the basis of age or prevailing medical condition. Artificial intelligence incorporated in the diagnosis equipment for analyzing the condition with minimum artifacts and accurate results can also help in improving patient outcome.

Visit our website now: https://www.grgonline.com/

[phonemantra-blog]

Eliquis Side Effects: What You Need to Know In the realm of anticoagulant medications, Eliquis has become a common choice for preventing blood clots and strokes. While Eliquis can be highly effective, it's crucial to be informed about its potential side effects to ensure safe usage. In this article, we'll delve into the world of Eliquis side effects, covering both the common and more serious ones, and provide valuable insights on how to manage them. Common Eliquis Side Effects Eliquis is known for its efficacy in preventing blood clots, but like all medications, it may come with some side effects. Understanding the common side effects is essential for those prescribed this medication. Bleeding Episodes: One of the most frequently reported side effects of Eliquis is bleeding, which can manifest as nosebleeds, bruising, or prolonged bleeding from minor cuts. While these side effects are typically mild, it's essential to keep your healthcare provider informed. Gastrointestinal Distress: Some individuals may experience digestive issues like stomach discomfort, indigestion, or diarrhea while taking Eliquis. These symptoms are generally manageable but should be discussed with your healthcare provider if they persist. Minor Headaches: Headaches, while less common, can occur as a side effect of Eliquis. They are usually mild and tend to resolve on their own. However, if headaches become severe or persistent, consult your healthcare provider. Serious Side Effects While Eliquis is generally well-tolerated, there are rare but serious side effects that require immediate medical attention. It's essential to be aware of these and seek help if any of them occur: Severe Bleeding: If you experience excessive or uncontrollable bleeding, such as heavy nosebleeds, blood in urine or stool, or prolonged bleeding after minor injuries, it's critical to contact your healthcare provider or seek emergency medical care. Allergic Reactions: Although uncommon, allergic reactions to Eliquis can occur. Symptoms may include skin rash, itching, swelling of the face, lips, tongue, or throat, and difficulty breathing. If you notice any of these signs, seek immediate medical attention. Liver Problems: Eliquis can, in rare cases, affect liver function. Signs of liver problems include yellowing of the skin or eyes (jaundice), dark urine, abdominal pain, or unexplained fatigue. If you experience any of these symptoms, contact your healthcare provider. Managing Eliquis Side Effects While Eliquis side effects are generally manageable, it's essential to be proactive in addressing them: Open Communication: Maintain open and regular communication with your healthcare provider. Inform them of any side effects, even if they seem minor. Follow Prescribed Dosage: Adhere to the prescribed dosage and schedule provided by your healthcare provider. Do not adjust the dosage without consulting them. Report Unusual Symptoms: If you notice unusual or severe symptoms that could be related to Eliquis, do not hesitate to contact your healthcare provider. It's better to seek professional advice promptly. Risk Factors and Precautions Certain factors may increase the likelihood of experiencing side effects from Eliquis. It's essential to be aware of these risk factors and take precautions accordingly: Age: Older individuals may have a higher risk of bleeding while taking Eliquis. If you are elderly, your healthcare provider may adjust your dosage or monitor you more closely. Medical History: Inform your healthcare provider about your medical history, especially if you have a history of bleeding disorders, liver disease, or gastrointestinal issues. This information will help them make informed decisions about your Eliquis prescription. Interactions with Other Medications: Eliquis can interact with other medications, including over-the-counter drugs and supplements. Always disclose all the medications you are taking to your healthcare provider to avoid potential interactions. Alcohol and Eliquis: Limit or avoid alcohol consumption while taking Eliquis, as alcohol can increase the risk of bleeding. Symptoms to Watch For Vigilance is key when taking Eliquis. Be mindful of any symptoms that may indicate potential side effects. These may include: Unexplained Bleeding: Any bleeding that cannot be attributed to an injury or known cause should be taken seriously. Allergic Reactions: If you experience skin rash, itching, swelling, or difficulty breathing, seek immediate medical attention. Jaundice: Yellowing of the skin or eyes (jaundice) could indicate a potential problem with your liver function and should be reported promptly. When to Contact Your Doctor Knowing when to contact your healthcare provider is vital for managing Eliquis side effects effectively: Severe or Prolonged Bleeding: Contact your doctor immediately if you experience severe or prolonged bleeding, as this could be a sign of a serious issue. Allergic Reactions: Seek medical attention without delay if you suspect you are having an allergic reaction to Eliquis. Unusual Symptoms: Any unusual or severe symptoms that you believe may be related to Eliquis should be discussed with your healthcare provider. Eliquis Side Effects FAQs   Q: What are the common side effects of Eliquis? A: Common side effects of Eliquis include bleeding, gastrointestinal discomfort, and minor headaches. Q: Are there any serious side effects associated with Eliquis? A: Yes, Eliquis can have serious side effects, such as severe bleeding, allergic reactions, and liver problems. Q: How can I manage minor side effects of Eliquis? A: Managing minor side effects may involve open communication with your healthcare provider and following their guidance. Q: What should I do if I experience severe bleeding while on Eliquis? A: If you experience severe or uncontrollable bleeding, seek immediate medical attention. Q: Can Eliquis cause allergic reactions, and what are the symptoms? A: Eliquis can rarely cause allergic reactions. Symptoms may include skin rash, swelling, and difficulty breathing. Q: Are there specific risk factors for experiencing side effects from Eliquis? A: Age, medical history, and interactions with other medications can be risk factors for side effects. Discuss your history with your healthcare provider. Q: Can alcohol worsen Eliquis side effects? A: Yes, alcohol can increase the risk of bleeding while taking Eliquis. Limit or avoid alcohol consumption. Q: What are the symptoms of liver problems that may be associated with Eliquis? A: Symptoms of liver problems include jaundice (yellowing of the skin or eyes), dark urine, abdominal pain, and unexplained fatigue. Q: When should I contact my doctor about Eliquis side effects? A: Contact your doctor immediately if you experience severe bleeding, allergic reactions, or unusual and severe symptoms while on Eliquis. Q: How can I monitor my symptoms while taking Eliquis? A: Pay close attention to unexplained bleeding, allergic reaction symptoms, and any unusual or severe side effects. Report them to your healthcare provider. Conclusion Understanding Eliquis side effects and how to manage them is crucial for those who rely on this medication for preventing blood clots and strokes. By staying informed about potential side effects, following precautions, and promptly reporting any concerning symptoms to your healthcare provider, you can use Eliquis safely and effectively. In the following sections, we will delve deeper into specific side effects and provide further guidance on Eliquis usage.  

[janineluciaa]

APIXABAN (ELIQUIS®) INFORMATION FOR PATIENTS, FAMILIES & CARERS

APIXABAN helps to stop blood clots from forming. You need to tell your doctor or pharmacist if you are taking any other medicines. This includes any vitamins or minerals, herbal supplements or medicines you bought without a prescription from a pharmacy, supermarket or health food store. It is a good idea to carry an up-to-date list of all your medicines. Consider wearing a medical alert bracelet.

Swallow the tablet whole. You can take it with or without food. Your pharmacist can put APIXABAN in a dose administration aid, such as a Webster Pak®.

Take your next tablet as soon as you remember. Then continue your APIXABAN as usual. If it is nearly time for your next tablet, do not take extra tablets to make up for the forgotten tablet. If you miss more than one tablet, or if you are unsure of what to do, talk to your doctor or pharmacist immediately.

[janineluciaa]

APIXABAN ALSO KNOWN AS: ELIQUIS

Apixaban is a blood thinner or anticoagulant. Anticoagulants help treat and prevent blood clots.

YOU ARE TAKING APIXABAN:

To help prevent stroke because you have atrial fibrillation

To help treat the blood clot in your leg (deep vein thrombosis or DVT) and/or blood clot in your lung (Pulmonary Embolism or PE)

To help prevent DVT or PE) after hip or knee surgery

 To help prevent another DVT or PE if you already had one

YOUR DOSE OF APIXABAN IS:

Atrial fibrillation: 5 mg twice a day (2.5 mg twice a day for some people)

Prevention of DVT or PE after hip or knee replacement: 2.5 mg twice a day

Treatment of DVT or PE: 10 mg twice a day for 1 week, followed by 5 mg twice a day for at least 3 months

Prevention of DVT or PE: 2.5 mg twice a day (5 mg twice a day for some people)

[janineluciaa]

Apixaban versus Warfarin in Patients with Atrial Fibrillation

Vitamin K antagonists are highly effective in preventing stroke in patients with atrial fibrillation but have several limitations. Apixaban is a novel oral direct factor Xa inhibitor that has been shown to reduce the risk of stroke in a similar population in comparison with aspirin.

In this randomized, double-blind trial, we compared apixaban (at a dose of 5 mg twice daily) with warfarin (target international normalized ratio, 2.0 to 3.0) in 18,201 patients with atrial fibrillation and at least one additional risk factor for stroke. The primary outcome was ischemic or hemorrhagic stroke or systemic embolism. The trial was designed to test for noninferiority, with key secondary objectives of testing for superiority with respect to the primary outcome and to the rates of major bleeding and death from any cause.

In patients with atrial fibrillation, apixaban was superior to warfarin in preventing stroke or systemic embolism, caused less bleeding, and resulted in lower mortality. (Funded by Bristol-Myers Squibb and Pfizer; ARISTOTLE ClinicalTrials.gov number, NCT00412984.)