#@BioScentDX

[mariebenz]

Trained Scent Dogs Can Quickly and Accurately Detect Covid-19

MedicalResearch.com Interview with: Prof. Tommy Dickey Ph.D. Distinguished Professor Emeritus Geography Department University of California Santa Barbara Santa Barbara, CA

MedicalResearch.com: What is the background for this study? Response:  I became interested in dog's sense of smell several years ago while doing therapy dog demonstrations at the California Science Center in Los Angeles during a special traveling exhibit "Dogs! A Science Tail." (Now at the Orlando Science Center).  I did a lot of research on this topic and taught children about it through the Los Angeles Public Library using my Great Pyrenees therapy dogs. Then, COVID broke out and I expanded my research into any work being done to possibly utilize scent dogs for screening and testing for COVID.  I found only a few such studies.  However, I fortuitously met Heather Junqueira of BioScent, Inc. (in Florida) online and she was beginning to successfully teach her beagles to detect COVID-related odors.  She agreed to co-author a peer-reviewed review paper with me.  That led to our first paper - Dickey, T, Junqueira, H. Toward the use of medical scent dogs for COVID-19 screening. J Osteopath Med 2021;1(2): 141-148. https://doi.org/10.1515/jom-2020-0222 When the COVID pandemic began to wane at the beginning of this year, I felt that it would be the perfect time to do this comprehensive follow-up review to see how far COVID scent dog research had progressed. To our amazement, research efforts had increased by almost tenfold and involved over 400 scientists using over 31,000 samples (including sniffings) from over 30 countries and that 29 peer reviewed papers had been published. Heather’s inspiration for doing scent dog work came when her father contracted cancer and she wanted to find better diagnostics.  She has since been successful in detecting non-small cell lung cancer with her trained beagles as well as COVID. MedicalResearch.com: Would you tell us a little about the type and/or breeding of the dogs? Response:  In the peer-reviewed studies, the number of different breeds and mixed breeds was 19.   Typical training periods dedicated to COVID scent detection were a few weeks. Labrador Retrievers and Belgian Malinois were most commonly used (nearly 100 times). These breeds were chosen because they have been used extensively in scent detection work for several purposes.  Other breeds, such as Heather’s beagles, have been used quite successfully as well. No obvious preference based on performance has been noted by breed, age, gender, age or even previous training for scent work. Interestingly, most of the dogs were not specifically bred to do COVID detection.  In fact, previously untrained dogs have the advantage that they are not as prone to indicating on scents other than the COVID-19 associated scent. Heather is one of the few scientists who actually breeds her dogs to be single purpose scent dogs (i.e., for COVID or other diseases). MedicalResearch.com: What are the main findings? 1)    Our review has shown that it safe to utilize scent dogs to directly screen and test individuals who may be infected with the COVID-19. 2)    The accuracy of the trained scent dog method is comparable to or in some cases superior to the real-time reverse transcription polymerase chain reaction (RT-PCR) test and the antigen (RAG) test. 3)    Trained scent dogs can be effectively used to provide quick (seconds to minutes), non-intrusive, and accurate results in public settings and thus reduce the spread of COVID. MedicalResearch.com: What should readers take away from your report? - Medical scent dogs deserve their place as a serious diagnostic methodology that could be particularly useful during pandemics, potentially as part of rapid health screenings in public spaces. We are confident that scent dogs will be useful in detecting a wide variety of diseases in the future. - We feel that the impressive international COVID scent dog research described in our paper, perhaps for the first time, demonstrates that medical scent dogs are ready for mainstream medical applications.  MedicalResearch.com: What recommendations do you have for future research as a results of this study? 1)    More studies utilizing more dogs would be beneficial 2)    More work in developing target samples is needed 3)    More research is needed in different public settings. MedicalResearch.com: Is there anything else you would like to add? Any disclosures? - More trained dogs will be needed for wide-spread, large-scale scent dog screening and testing.   The training and field use of scent dogs may benefit from the recruitment of dog owners who are already involved in recreational scent work under the auspices of the American Kennel Club and other organizations worldwide. - Is the use of scent dogs cost effective?  Much of the research in this review was in fact motivated by the need for rapid, inexpensive, and lower technological testing in developing nations.  More research into the economics is needed. - Perhaps the greatest challenge to the use of medical scent dogs is the implementation of wide-spread, large-scale programs, which will require funding and development of infrastructure that is responsible for certification, protocol standards, and deployments. This may be more of a challenge in the U.S. for a variety of bureaucratic reasons. Other nations face a variety of obstacles, but the large number of scent dogs already used in practical applications (seen in our paper’s References and Tables) suggests that their governments are quite supportive of the common use of medical scent dogs and may not place as many governmental barriers. Citation: Dickey, Tommy and Junqueira, Heather. "COVID-19 scent dog research highlights and synthesis during the pandemic of December 2019−April 2023" Journal of Osteopathic Medicine, 2023. https://doi.org/10.1515/jom-2023-0104 The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.     Read the full article

[ezatluba]

DOGS CAN SNIFF OUT CANCER WITH NEARLY 97% ACCURACY, SAYS STUDY

Dr. Dog

Researchers across the globe are experimenting with ways to use artificial intelligence and other high-tech means to detect cancer.

At the same time, one startup in Florida is taking a decidedly low-tech approach to the problem by turning over the task of sniffing out cancer to dogs — and the animals, the company says, are surprisingly good at it.

Smell Test

On Monday, Florida’s BioScentDx presented its study of canine cancer detection at Experimental Biology, a life sciences and biomedical research conference.

For the study, the researchers used a behavioral technique called “clicker training” to teach four beagles to differentiate between healthy blood samples and ones taken from people with malignant lung cancer.

One of the dogs, Snuggles, was “unmotivated to perform,” according to a press release (relatable, right?). But the other three averaged a 96.7 percent accuracy at identifying the lung cancer samples and 97.5 percent accuracy at spotting the healthy samples.

Canine Tracking

According to researcher Heather Junqueira, the team sees two ways scientists could harness this puppy power to detect cancer.

“One is using canine scent detection as a screening method for cancers,” she said in the press release, “and the other would be to determine the biologic compounds the dogs detect and then design cancer-screening tests based on those compounds.”

[fitnesshealthyoga-blog]

New Post has been published on https://fitnesshealthyoga.com/dogs-sniff-out-lung-cancer-from-blood-samples-with-97-percent-accuracy-study-claims/

Dogs sniff out lung cancer from blood samples with 97 percent accuracy, study claims

A new study presented on Monday has found that beagles can be trained to detect lung cancer from human blood samples with 97 percent accuracy. (Stock image)

Dogs can smell lung cancer with 97 percent accuracy, according to new research.

The study, presented Monday at the annual meeting of the American Society for Biochemistry and Molecular Biology in Orlando, looked at how four beagles, all two years old, identified human blood samples — either with lung cancer or without.

FORMER OLYMPIC HOCKEY PLAYER SAYS RADON CAUSED STAGE 4 LUNG CANCER

Though one of the dogs, named Snuggles, was “unmotivated to perform,” according to a statement, the other three were able to correctly identify blood samples with lung cancer 96.7 percent of the time as well as normal blood samples 97.5 percent of the time.

The experiment, conducted by researchers at the Florida pharmaceutical lab BioScentDx, trained the beagles to differentiate between blood samples from lung cancer patients and normal blood samples.

The beagles were able to detect the differences because dogs have smell receptors that are 10,000 times more accurate than humans’, according to the statement.

IMMUNE THERAPY SCORES BIG WIN AGAINST LUNG CANCER IN STUDY

Heather Junqueira, who led the study, said her findings could lead to other cancer-screening tools, which are important because early cancer detection often means higher chances of survival.

“This work is very exciting because it paves the way for further research along two paths, both of which could lead to new cancer-detection tools,” Junqueira said.

“One is using canine scent detection as a screening method for cancers, and the other would be to determine the biologic compounds the dogs detect and then design cancer-screening tests based on those compounds,” she added.

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[hirzilla]

Vérből szagolják ki a rákot a kutyák http://hirzilla.hu/hirek/online-hirek/24-hu/2019/04/10/verbol-szagoljak-ki-a-rakot-a-kutyak/?feed_id=30511&_unique_id=5cad72871a5f7 Egy új tanulmány szerint a kutyák nagy pontossággal képesek vérminta alapján kiszagolni a rákot – írja az MTI. A faj szaglásérzékelése az emberénél tízezerszer precízebb, az élőlények olyan szagokat is meg tudnak különböztetni, amelyeket mi érzékelni sem tudunk. A kísérletben a kutyák közel 97 százalékos pontossággal választották ki a rákos betegektől származó vérmintákat. A szakértők szerint a rosszindulatú daganatok kiszűrésére alkalmas nagy érzékenységű teszt ezrek életét mentheti meg, emellett a betegség kezelését is megváltoztathatja. Heather Junqueira, a BioScentDX munkatársa és kollégái négy beagle-t tanítottak be arra, hogy képesek legyenek felismerni a különbségeket az egészséges alanyoktól és a tüdőrákban szenvedőktől vett vér között. Az egyik beagle ugyan nem volt hajlandó teljesíteni a feladatot, a többi viszont az esetek 96,7 százalékában helyesen azonosították a tüdőrákos, és 97,5 százalékos pontossággal a normál vérmintákat. Fotó: iStock A kutatók úgy vélik, hogy nagy lehetőségek rejlik ebben a tesztelési módszerben, és tovább akarják fejleszteni a technikát. A csapat újabb vizsgálatokkal akarja megállapítani, hogy a kutyák milyen biológiai összetevők alapján fedezik fel a daganat jeleit, ezek alapján pedig újabb szűrőeljárást akarnak kifejleszteni. Kiemelt fotó: iStock https://24.hu/tudomany/2019/04/10/kutyak-rak-eszlelese/

[interestingfactsquotes]

Could Dogs Be the Secret to Early Cancer Detection?

Interesting Facts About Dogs Can dogs use their tremendous sense of scent to detect lung cancer cells early in blood samples?  That may in fact be the case.  Yahoo.com has the story. Dan Steel / Getty Scientists have discovered a breakthrough that could lead to earlier lung cancer diagnosis. According to a new study conducted by BioScentDx firm researchers, a group of beagles were able to identify 96.7 percent of lung cancer cells in blood samples from human subjects, while maintaining Click here to view original web page at www.yahoo.com Read the full article

[stiri-noi]

VIDEO Cum ar putea câinii să fie folosiți în depistarea cancerului

[destinationsante-yahoopartner]

L’odorat canin pour diagnostiquer le cancer

Grisha Bruev/shutterstock.com

Plusieurs études ont déjà souligné l’intérêt d’utiliser l’odorat exceptionnel des chiens dans le dépistage et le diagnostic du cancer. Après l’odeur de la sueur, celle du sang pourrait être soumise aux narines canines. L’équipe américaine à l’origine de ce travail espère déterminer quels éléments sanguins servent aux chiens à repérer la présence d’une tumeur.

Le nez du chien est 10 000 fois plus efficace que celui de l’être humain. Alors pourquoi ne pas le mettre à contribution dans le dépistage et le diagnostic du cancer ? Une idée lancée depuis plusieurs années déjà par les scientifiques.

Une nouvelle étude va plus loin : l’équipe de Heather Junqueira du laboratoire BioScentDx a testé l’efficacité de l’odorat canin sur des prélèvements sanguins de malades et de personnes contrôle. Résultats, les trois beagles dressés pour l’occasion ont réussi à distinguer les malades des autres à 97%. Une performance !

Ce constat encourageant les a par ailleurs incités à mener plus avant leurs recherches. Prochain objectif, déterminer quels composants du sang permettent au chien de distinguer les malades des personnes saines. Puis développer un test de dépistage basé sur ces composants. Retrouvez cet article sur DestinationSante.com

[ultraisabarrosmartins1978]

Cães podem farejar câncer no sangue e saliva com 97% de precisão

Os cães são conhecidos por seu poderoso faro e agora um estudo observou que o olfato evoluído deles é capaz de detectar câncer em amostras de sangue e de saliva com quase 97% de precisão.

Isso se explica porque os cães têm receptores olfativos 10 mil vezes mais precisos que os de humanos, tornando-os altamente sensíveis a odores que não conseguimos perceber.

CONHEÇA OS PRINCIPAIS DIREITOS DOS PACIENTES COM CÂNCER

Em um dos testes realizados, os animais apontaram indícios de câncer de mama em uma paciente, 18 meses antes de o tumor ser diagnosticado em um exame de mamografia.

Como o teste funciona?

O processo do teste é simples. Os voluntários recebem um kit, que inclui uma máscara cirúrgica para ser usada por um determinado período. Posteriormente, esse material é embalado e devolvido aos pesquisadores que o insere em uma lata de metal e apresenta aos cães treinados. Se o câncer é detectado, os cães se sentam em frente a essa lata. O teste então é repetido para confirmação, com outro grupo de cães treinados em tipos específicos de tumores.

Atualmente, câncer de mama e pulmão podem ser detectados. Logo, o teste vai evoluir para incluir próstata, colorretal e melanoma.

Além das máscaras, amostras de sangue de pacientes também são utilizadas. O teste é feito de forma bastante semelhante, sempre oferecendo petisco para os cães associarem o agrado ao odor.

View this post on Instagram

Did you know our cancer sniffing Beagles are capable of detecting cancer with an amazing 97% accuracy and may be able to find it up 18 months ahead of traditional testing? We know early detection can save lives and these dogs are helping in identifying cancer at the earliest stage. Find the link in our Bio and get screened! #beagles #cancer #cancerscreening #cancersucks #eradicatecancer #beagle

A post shared by BioScentDX (@bioscentdx) on May 1, 2019 at 8:05am PDT

Os pesquisadores agora planejam realizar um estudo de acompanhamento para entender exatamente quais componentes químicos os cães estão cheirando para detectar o câncer.

De acordo com uma das autoras do estudo, a pesquisadora Heather Junqueira, do laboratório BioScentDX, os resultados podem levar a novas abordagens de detecção da doença. “Embora atualmente não haja cura para o câncer, a detecção precoce oferece a melhor esperança de sobrevivência”, afirmou.

Veja também: Câncer: exame detecta tumor 10 anos antes da doença aparecer

Cães podem farejar câncer no sangue e saliva com 97% de precisãopublicado primeiro em como se vestir bem

[myserendipities]

On Monday, Florida’s BioScentDx presented its study of canine cancer detection at Experimental Biology, a life sciences and biomedical research conference. For the study, the researchers used a behavioral technique called “clicker training” to teach four beagles to differentiate between healthy blood samples and ones taken from people with malignant lung cancer. One of the dogs, Snuggles, was “unmotivated to perform,” according to a press release (relatable, right?). But the other three averaged a 96.7 percent accuracy at identifying the lung cancer samples and 97.5 percent accuracy at spotting the healthy samples. According to researcher Heather Junqueira, the team sees two ways scientists could harness this puppy power to detect cancer. “One is using canine scent detection as a screening method for cancers,” she said in the press release, “and the other would be to determine the biologic compounds the dogs detect and then design cancer-screening tests based on those compounds.”

Dogs Can Sniff out Cancer With Nearly 97% Accuracy, Says Study

[mariebenz]

Highly Trained Beagles Can Smell Lung Cancer in Serum

MedicalResearch.com Interview with:

Dr. Quinn Thomas A. Quinn, DO, FAOCOPM Clinical Professor Lake Erie College of Osteopathic Medicine Bradenton  MedicalResearch.com: What is the background for this study? What are the main findings? Response: Canine scent detection of lung cancer is showing evidence of being an effective, safe and cost effective method of early detection of lung as well as other types of cancer. Lung cancer is the leading cause of cancer deaths and early detection has proven to be one of the most effective ways to reduce the mortality and morbidity of this deadly disease.  In a collaborative study conducted by the Lake Erie College of Osteopathic Medicine (LECOM) and BioScentDX, a canine training and research facility, we were able to show that highly trained dogs can detect non-small cell cancer of the lung by scent alone.  For this study we chose to use Beagles because of their superior scent capability as well as their temperament, sociability and easy trainability.  The dogs proved to be able, in this double blind study, to detect lung cancer in blood serum with a 96.7% sensitivity and a 97.5% specificity. The dogs underwent an eight-week training program using the clicker/treat training method.  We trained four Beagles for this study but one of the dogs did not respond well to the training methods and had to be removed from the program. That dog was retrained as a service dog for a handicapped child. MedicalResearch.com: What should readers take away from your report? Response: Certain dogs, from the scent hound group such as Beagles, can be trained to use their scent detection capability to detect lung cancer with a high degree of accuracy.  In the Journal of the American Osteopathic Association article, the dogs detected lung cancer using blood serum.  Our research continues and we have also trained dogs to detect cancers using saliva and exhaled breath samples with equal accuracy.  We are also successfully training dogs to detect breast and colorectal cancers.  The samples can be easily collected at the physician’s office or clinic and sent to the BioScent Laboratory for evaluation by the dogs.  When evaluating an unknown sample, every sample is examined by four separate dogs to assure accuracy.  Every dog is routinely retested every three months, using known positive and negative samples, to assure that the dogs maintain their level of accuracy.  If the accuracy of any dog declines they are removed from the program to be retrained and then retested.  They are returned to the program only after their accuracy returns to accepted levels.   MedicalResearch.com: What recommendations do you have for future research as a result of this work? Response: We are barely scratching the surface in this new and exciting research.  Just a few of the multiple areas that need to be investigated are: Can the dogs detect small cell lung cancer (SCLC) as well as non-small cell lung cancer (NSCLC)?  Can the dogs, by scent alone, distinguish between SCLC and NSCLC? At what stage can the dogs detect recurrent lung cancer?  Will chemotherapy medications effect the dogs ability to detect recurrence of cancer?  Will certain medical conditions, such as diabetes, have an effect on the dogs ability to detect cancer?  Right now we have more questions than answers. Our researchers at LECOM are also attempting to fractionate and identify the biomarkers that the dogs are identifying in the lung cancer positive exhaled breath condensate samples.  At each stage of the fractionation the samples are presented back to the dogs to determine which of the fractionations contain the cancer biomarkers.  Once isolated, the process of identifying the biomarkers will begin. MedicalResearch.com: Is there anything else you would like to add? Response: Recently we bred our most accurate female Beagle with our most accurate male Beagle and the resulting litter of six puppies are just coming to the age where they can enter the training program.  We are looking forward to see how well they will perform. Citation: Accuracy of Canine Scent Detection of Non–Small Cell Lung Cancer in Blood Serum Heather Junqueira, CVT; Thomas A. Quinn, DO; Roger Biringer, PhD; Mohamed Hussein, DVM, PhD; Courtney Smeriglio, OMS II; Luisa Barrueto, OMS II; Jordan Finizio, OMS II; Xi Ying “Michelle” Huang, OMS II he Journal of the American Osteopathic Association Published Online First on June 17, 2019. doi:10.7556/jaoa.2019.077     The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.   Read the full article

[hirzilla]

Kiszagolják a kutyák a rákot - így működik a vérteszt http://hirzilla.hu/hirek/online-hirek/infostart-hu/2019/04/10/kiszagoljak-a-kutyak-a-rakot-igy-mukodik-a-verteszt/?feed_id=31666&_unique_id=5cadd113bf112 A kutyák szaglásérzékelése tízezerszer pontosabb, mint az emberé, olyan szagokat is meg tudnak különböztetni, amelyeket az ember nem érzékel. A kutatásban a kutyák 97 százalékos pontossággal választották ki a rákban szenvedők vérmintáit - hangsúlyozták a tanulmány szerzői. A rák kiszűrésére alkalmas nagy érzékenységű teszt potenciálisan ezrek életét mentheti meg és a betegség kezelésének módját is megváltoztathatja - mondták a kutatók. Heather Junqueira, a BioScentDX kutatója és kollégái négy beagle-t tanítottak meg arra, hogy különbséget tegyenek a normális vér és tüdőrákban szenvedő páciensek vére között. A tanulmány szerint az egyik beagle nem volt hajlandó teljesíteni a feladatot, de a többi három az esetek 96,7 százalékában helyesen választotta ki a tüdőrákos vérmintákat, és 97,5 százalékos biztonsággal a normál vérmintákat. A kutatók szerint nagy lehetőségek rejlenek ebben a nem invazív tesztelésben, és tovább akarják fejleszteni a rákszűrésnek ezt a módját. További kutatásokkal akarják meghatározni, hogy a kutyák milyen biológiai összetevőt érzékelnek, és ez alapján akarnak kifejleszteni újabb rákszűrő teszteket. Nyitókép: Pixabay