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Best medicines to keep your hair healthy.

Beginning in 1988, Rogaine lotion was accessible only by prescription, and just in two per cent concentration.  Back in 1995, the FDA decided minoxidil lotion was adequately safe for use with no prescription and Rogaine was soon available over-the-counter in pharmacies and grocery shops.  Generic versions of Rogaine became accessible once the patent on minoxidil died, and the assortment of concentrations grew up to five percent.  The five percent strength lotion is chosen by people using cream, because it produces faster results than the two percentage concentration. Dutasteride is currently being studied for baldness, but results haven't yet been released.

Dutasteride, avodart, was published for treatment of benign prostate hypertrophy at the end of 2001.   Type II is located in hair and skin in the prostate gland and Type I'm.  Women have type II with thinning hair, women can gain from Dutasteride.  I regularly place my male patients on Dutasteride if they are part of the little group who continue to lose hair whilst on Propecia.  Avodart (dutasteride 0.5 mg) daily lowers DHT 90% whereas finasteride only lowers DHT 65 -- 70%.  Even though it hasn't yet been accepted by the FDA for hair loss, I prescribe Avodart when Propecia is not strong enough.

Clinical studies have been conducted through which some men and women with pattern hair loss applied Rogaine to their scalps, and many others with pattern hair loss applied a placebo: exactly the identical mixture of water, alcohol, and propylene glycol used in Rogaine, but minus the minoxidil.  The women and men selected for the study had thin hair or baldness at the top of their heads, in which minoxidil is the most effective at promoting baldness.  The treatment's effectiveness was compared to placebo cream.  The results of clinical studies involving thousands of women and men have shown Rogaine can produce a statistically significant increase in baldness.

In men vulnerable to pattern baldness, certain scalp hair follicles are more prone to react in a negative ways to elevated levels of DHT in the blood.  The most susceptible hair follicles are typically located at the temples, front, along with the mind, but all of hair follicles may eventually be influenced to some degree by regular DHT levels.   The final result is hairs, and fewer and fewer hair follicles producing hairs. Hair transplant patients may use minoxidil.  Many surgeons recommend using it in just a couple of weeks after surgery to promote the growth of the hair follicles.   1 medication, Propecia (finasteride), is usually prescribed for men only, due to possible side effects when taken by pregnant women.  Still another, Rogaine (minoxidil), is helpful for treating both men and women.  The previous two, high-estrogen oral contraceptives and aldactone (spironolactone) are usually prescribed for girls only, on account of the chance of undesirable feminizing side effects in men.

also read Best Foam Wrap Lotion For Relaxed Hair by same author

Propecia blocks from converting testosterone to DHT a sort of 5-alpha-reductase found chiefly in the prostate gland, called type-II 5-alpha-reductase.   Over many years, DHT in the bloodstream signals their growth phase to be shortened by hair follicles and to miniaturize.  By reducing the amount of DHT in the blood, Propecia lessens the strength of the DHT hormone message, so a number of the follicles which would have quit rather continue to produce new hairs. Double blind clinical tests have shown that Propecia helps guys keep the hair that they have.  In a recent study, eighty-three percentage of men taking Propecia maintained their hair at the top of the heads (vertex area), compared to twenty-eight percent of men taking a placebo.  In the same study, seventeen percent of the men taking Propecia still experienced measurable hair loss, but seventy two percent of the men taking the placebo also undergone additional hair loss.  Following the initial couple of years, results of the team taking Propecia continued to increase. Research on minoxidil's potential as a anti-baldness medication started after a few Loniten patients noticed substantial new hair growth, a condition physicians call hypertrichosis.  Normally the new hair growth has been on the mind and was desired, but sometimes it also happened on the arms, chest, back, and other regions.  So researchers worked on a lotion form of the medicine that could be put on the face or scalp where it was wanted to lead hair development. Topical medications that could be integrated to block the receptor site are flutamide, progesterone, zinc additives acid, spironolactone, dutasteride, and finasteride.   Make their prescription blend of some or most of medications.  These drugs are often added to a minoxidil solution, and also also the entire blend may be applied one or two times . Merck, the manufacturer of Proscar for the prostate and Propecia for hair loss, has taken the position that women shouldn't touch with the pill or the bottle if they're pregnant, and they should not have sex with guys that are taking the medication.  The reason for that is that 5-alpha-reductase, if inhibited at a growing fetus, might lead to a male child with a very small penis.  People that are missing the receptor 5-alpha-reductase type II--and you can find households of them--have boys that are born looking like small women.  But the testicles descend and they become men.  Considering that the facts, Merck set a warning in their bottles of Propecia and Proscar.  Though this defies logic and might sound ludicrous (even though it was radioactive you'd have a hard time measuring it and also a woman would have to have gallons and gallons of semen to absorb enough to quantify it), Merck did not want to take the risk.  Compare this to this warning on a bottle of Jim Beam.  It does not say women should not have intercourse with drunk men, it says women should not get drunk.  However, no physician --like me--would inform a man individual it's perfectly safe to use Proscar or Propecia and then have sex with a pregnant spouse because a certain number of boys have been born with this birth abnormality for unknown reasons and it could be blamed on the medication.

Continuous treatment is required to maintain this benefit, as 5-alpha-reductase will keep on converting testosterone into DHT when therapy is discontinued.  The benefit of using Propecia for any time period is still realized; Propecia buys time for men with a genetic predisposition for hair loss.  The DHT message to stop growing hair must continue for many years, and often many years, for DHT-sensitive hair follicles to get the message and stop growing new hairs.  The clock has been stopped, When the DHT message is interrupted for a time period.  To put it differently, if a thirty-year-old man who would shed his hair by age sixty uses Propecia for twenty five years and then quits, he will delay the age when he'd lose his hair to age .  When use is stopped, the advantage of using Propecia for twenty years isn't lost. Higher estrogen oral contraceptives such as Ortho Tri-Cyclen or Ortho Novum frequently work nicely to inhibit production of androgens (such as testosterone) from the ovaries and adrenal glands, which causes reduced levels of DHT, therefor, and such stops hair thinning.

Spironolactone is for women what Propecia is in preventing baldness with about precisely the same success rate for men.  Spironolactone binds to DHT receptor sites on hair follicles, A, thus blocking DHT from getting its own hair loss message.  This medicine is used just for women with androgenetic alopecia (genetic pattern hair loss), since it can produce undesirable side effects in men. Lotion is applied on the scalp two times.  The lotion form of the drug causes the hair-growing effect to happen on the scalp only, and not on different parts of the human body.  When applied as directed there is not any impact on blood pressure.  Rogaine is a remedy, not a cure.  This means that the lotion has to be applied to the scalp twice per day for those benefits to continue.  Skipping a day or two occasionally isn't likely to make any measurable difference in the efficacy of minoxidil treatment.  After several months of use that is discontinued , no matter how the regrown hairs will probably be shed. Spironolactone is regarded as a pill or made into a lotion that's applied to the scalp, usually along with minoxidil, when used as a baldness treatment.

There was a report of a single percent melatonin put on the scalp of post menopausal women, leading to thicker hair after twelve weeks of usage.  There is absolutely no mechanism for why it works.

This chapter shows that the four most medications proven for treating genetic hair loss clinically.  All four of those drugs were originally approved by the FDA for treating clinical conditions other than hair loss.  All can slow down the rate of baldness that is inherited, and in many cases they can help hair follicles which have shut down to begin to grow hair.   This chapter also includes a last section on remedies.

In 1998, after years of further testing for a hair loss treatment, finasteride was also accepted in pill form, at a lower dose, as an anti-baldness therapy.  It's sold as a pharmaceutical prostate medication in tablet form under the brand name Proscar.  It is sold in tablets.  The dose is sufficient, for treating hair loss.  Propecia's hair loss reduction effect happens at a lower dose than that needed to take care of enlarged prostrate glands.

Along with decreasing androgenetic baldness, the benefits of taking birth control pills contain decrease of the danger of pregnancy, improved skin tone, reduced acne, and for women beginning the initial stages of menopause, higher bone mass, decreased occurrence of hot flashes, somewhat tempered mood swings, and reduced irritability. High Estrogen Oral Contraceptives

The risks of taking oral contraceptives consist of risk of endometrial (uterine) cancer, also, for older women, an increased risk of disease such as strokes and heart attacks.  

Researchers aren't certain increase hair growth or minoxidil works to stop hair loss.  It is understood that it does not impact DHT levels in blood flow.  Minoxidil is a vasodilator, meaning it helps blood vessels enlarge.  Other vasodilators, but do not stop baldness or increase hair growth.  Minoxidil lotion appears to work just on active hair follicles nevertheless capable of producing some hair, even when hair produced is just"peach fuzz."  1 symptom of people with hereditary pattern hair loss is the progressive miniaturization of hair follicles in the end of each growth cycle, leading to finer and finer hairs being generated. Propecia treatment might cause a loss of sex drive in one to 2 percent of patients as a result of reducing levels of DHT circulating in the blood.  Treatment with Viagra can be useful in such instances.  Discontinuing Propecia eliminates this potential side effect, if it occurs.

There is also a small risk of reducing the quantity of ejaculate if the prostate gland has been diminished in size as a consequence of Propecia treatment.  Activity remains normal.  Discontinuing Propecia eradicates this potential side effect.

Finasteride effectively blocks one kind of the enzyme that converts testosterone to DHT.  By blocking the conversion of testosterone into DHT, Propecia prevents the"hair loss message" from getting to hair follicles that are genetically programmed to be sensitive to DHT.  This helps prevent further hair loss, and in several cases regular Propecia use really leads to significant hair re-growth of lately lost hairs.

In 1988, Rogaine lotion became the first medicine approved by the FDA for treating genetic hair loss.  The medicine is a colorless and odorless liquid applied to the scalp.  When used as a baldness treatment in cream form, rogaine is the brand name for the medication minoxidil.  Minoxidil had already been FDA approved in pill form for a prescription medicine for treating hypertension.  The brand name for pills is Loniten.

The single medication proven to treat genetic pattern hair loss is Propecia.   Propecia is the brand name for the medication finasteride.   To the joy of some individuals taking finasteride for enlarged prostate glands, hair loss was decreased, and often re-growth of baldness lost. Scientists figured that if they could create a medication to regulate the action of 5-alpha-reductase they can accomplish a number of the favorable effects of the genetic trait, for example prostate gland normalization and, later hair loss prevention. Minoxidil lotion is safe.  Only very small quantities of it reach the blood, when used as directed and applied to the scalp.  The risk of serious side effects is very small. Those likely to achieve the best results with Rogaine are at the early stages of pattern hair loss.  On the average folks get better outcomes than folks.  Those with baldness or thinning on the top of their minds get better results.  People with hair loss, particularly women, tend to get much better outcomes than those with spots.  Those with spots usually show more regrowth than those with large bald spots.

A research conducted having a 1 percent Zinc Pyrithione ZnP solution each day to the scalp showed that subjects needed thicker hair .    The study concluded that Zinc Pyrithione kills yeast and bacteria in the glands and hair follicles resulting in healthier hairs.  Another possibility is the Zinc itself may inhibit 5-alpha-reductase from the hair follicle. With Propecia usage, the rate of hair loss slows, and in many cases stops.  In many people, some recently miniaturized hair follicles start to grow back to normal size, and begin to grow normal size hairs .  This results in hair that is increased.  The degree of hair regrowth can vary from no quantifiable regrowth, to significant regrowth. Minoxidil seems to reduce the speed of hair follicle miniaturization, and can cause hair follicles which formerly produced full-size hairs, but have lately become miniaturized, to increase in size and start to grow full size hairs .  Additionally, the enlarged follicles appear to stay in the anagen, or expansion phase for a longer period.  A longer growth phase ends in the creation of longer hairs, and a look of more hair.   Countless drugs, herbs, nutrients, and compounds have been claimed to prevent or reverse baldness, nevertheless when tested clinically in well regulated, double-blind clinical trials, almost none have been shown to work.  Obviously, countless bogus hair loss products continue to make claims about their effectiveness, including presenting bogus"testimonials" by clinical doctors and users,"scientific proof" of effectiveness, as well as fake results from"nicely controlled, double-blind clinical trials."   Hair loss treatments also sell well in Europe, in Asia, and Central and South America. A woman taking finasteride would have just a small decrease DHT levels because most of the effect of finasteride is on type-II 5-alpha-reductase that's primarily made in prostate glands.  Women who take finasteride and become pregnant can lead to a male embryo to develop ambiguous genitals, also have female characteristics until puberty (at puberty, the child's genitals normalize). For several years before it was accepted as a hair loss treatment, a level of security was created for finasteride, the active ingredient in Propecia.   Based on studies of hormone breakdown products found in the urine, it appears to affect only the 5-alpha-reductase enzyme, and not other hormones in the blood like testosterone.  Propecia is not an antiandrogen.  In fact, levels of testosterone in the blood often increase by ten to fifteen per cent when taking Propecia.   Some potential side effects of finasteride remedy for baldness might be regarded as beneficial, such as possible shrinking of the prostate gland in males susceptible to an enlarged prostate.  

Direction of women's hormone levels is an easy task, nor one where medications are prescribed without consideration of the range of advantages and risks.

Birth control pills have a combination of estrogen and testosterone hormones.  Since they were introduced in 1960, the estrogen component of oral contraceptives was decreased from .150 mg per tablet to .020-.035 milligrams.  An birth control pill with .035 mg of estrogen is considered a"high-estrogen" oral contraceptive.  And for reference, the estrogen level in oral contraceptives is a few times higher than that of estrogen replacement drugs prescribed .

Propecia may also help regrow lost hair in addition to stopping further baldness.   Within this study, only one percent of men taking Propecia continued to possess hair loss at the top of their minds, while thirty-three percent of men taking a placebo revealed a diminished hair count in this region.

The story of finasteride begins with scientists that had been working with a family in the Dominican Republic who had a hereditary characteristic that caused them to give birth to male children with ambiguous genitalia.  Infants weren't affected.  In many cases it was hard to determine such a baby's sex by observation alone.  When hormone levels within those affected individuals increased, these boys normalized.  They had children of their own, and perpetuated the trait.

The most frequent side effect when used as directed would be slight scalp irritation.  In clinical trials involving 6,000 men and women around seven percent of these using 2 percent strength Rogaine lotion experienced some degree of scalp itching, inflammation, dryness, or flaking.  A smaller percentage of patients experience an increased pulse rate.

Both of these states can affect around 2 percent of men in the first month of usage, but fall to approximately a half percent when measured after two years.

1 drawback to spironolactone cream is a unpleasant smell, which can be made worse when combined in the same container with Rogaine. Some physicians prepare custom-blended minoxidil cream, with added ingredients to decrease the danger of inflammation and increase absorption.  1 such additive is tretinoin (Retin-A): Tretinoin is a prescription medication applied to the skin, and is also well known for helping to reduce facial wrinkles.  Minoxidil lotion implemented with low concentrations of tretinoin has been show to encourage greater hair growth--and possibly faster results--compared to minoxidil used alone.  The absorption of minoxidil can increase throughout skin as well as having extra hair growth promoting effects.  In addition to advantages and the dangers of use tretinoin adds additional risk of inflammation and skin irritation. Minoxidil takes time to create results.  A change in appearance occurs in a matter of months, when 2 percent minoxidil can be used per day; five% minoxidil produces faster results.  Before significant benefit can be seen, several months are often required.  The outcomes may improve with twice-daily use that is continuous.  The benefit is achieved following twelve months of use, and at that point hair regrowth will stabilize.

Minoxidil lotion may be used at precisely the exact same time as Propecia tablets.  The results are far better than when either medication used alone.

One milligram Propecia tablet taken every day is the normal prescribed dose for baldness treatment.   This usually means that a pill must be taken every day to last.  The hair loss process aids, when Propecia is stopped.

Aldactone is the newest name for spironolactone, a prescription medication used in tablet form for treating women with three common issues seen by dermatologists: acne, hirsutism (too much hair, particularly on the face), and androgenetic alopecia.  The March 2005 British Journal of Dermatology reported on a study which revealed eighty percent of women getting oral antiandrogens (spironolcatone) could expect to see no progression of the female pattern baldness, enhanced likelihood of stopping their baldness, or getting some hair back, after taking the medication for a year at 200 mg every day. Ladies inherit a trend for routine hair loss as guys do.  However, in women the DHT message is obstructed by significant levels of estrogens.  As girls start perimenopause around age forty estrogen levels start to decline, and in menopause most girls are by age fifty-five to fifty-eight.  While levels decline along with estrogen and progesterone, the DHT message will finally start to get through, and thinning hair can result.

It was observed that the men in this category being studied didn't suffer from enlarged prostate glands, never developed prostate cancer, nor did they lose their own hair.  No pattern baldness!  Genetic research showed that their gene for generating the 5-alpha-reductase enzyme was dormant.  To DHT, testosterone in the bloodstream wasn't easily converted with no 5-alpha-reductase enzyme.  The low levels of DHT that led prevented their hair follicles from getting the concept to have shorter growth cycles and miniaturization.

Also, for those who stop the minoxidil for a few months the hairs which would have been shed in the event the minoxidil had not averted follicle miniaturization will also be dropped as those follicles begin to shrink.  So both regrown hairs and hairs that would have been lost if not for the minoxidil use may be drop after stopping use.

Another lotion additive is betamethasone valerate.  Along with reducing potential scalp irritation, it might also enhance the hair recovery impact of minoxidil in 2 ways: first, it helps block the metabolism of testosterone in the tissues of the hair follicle in which the hormone signal to"stop producing new hairs" occurs.  Blocking this signal may maintain more hairs growing.  Second, betamethasone valerate can help to disperse the white blood cells that are called up to push at out the hair shaft.  The white blood cells scar that the hair follicle, decreasing the follicle's ability in doing so.  By reducing scarring valerate might help keep the hair follicles energetic to more hair growth cycles.   Some girls using additional strength minoxidil cream (5% ) experience increased facial hair growth.  This side effect tends to decrease after the first few months of therapy, or 2 percent minoxidil can be utilized.  Hair growth resumes, when treatment is stopped normal.  Minoxidil treatment does not work with thinning hair due to pattern hair loss.  It is less successful for hair loss in the hairline compared on the top of the head.  It is not as effective on large bald spots than small ones.  It is not as effective on bald spots compared to diffuse locations that are thin.  It is successful on glistening regions than those with baldness that is recent.

For some people, it appears to have no effect in any respect.  There is rate of baldness, but no new hair growth that is visible.  Women and some men experience fresh hair growth, but not sufficient to cover hair areas that are thin.  Others like dense new hair growth with regions that had been thin developing hair thinning very similar to areas which weren't affected by baldness.