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All You Need to Know About Trodelvy and Its Therapeutic Advancements

In the landscape of oncology, advancements in targeted therapies continue to reshape the way we approach and treat various types of cancer. One such groundbreaking therapeutic drug is Trodelvy (sacituzumab govitecan-hziy), a novel antibody-drug conjugate approved for the treatment of metastatic triple-negative breast cancer (mTNBC), hormone receptor (HR)-positive and human epidermal growth factor receptor 2 (HER2)-negative breast cancer, and metastatic urothelial cancer (mUC).

Approved by the FDA, Trodelvy offers hope to patients facing limited treatment options, demonstrating promising efficacy and tolerability in clinical trials.

Understanding Trodelvy: Trodelvy is a first-in-class antibody-drug conjugate (ADC) designed to selectively target and deliver chemotherapy to cancer cells expressing the Trop-2 receptor. Trop-2 is overexpressed in a variety of solid tumors, including triple-negative breast cancer, HR-positive/HER2-negative breast cancer, and urothelial cancer, making it an attractive target for therapy. The medicinal product is supplied for injection: 180 mg lyophilized powder in single-dose vials for reconstitution for intravenous use.

Indications for Use: Trodelvy 200 mg injection is indicated for the treatment of: Metastatic Triple-Negative Breast Cancer (mTNBC): This therapeutic drug is approved for patients with unresectable locally advanced or metastatic triple-negative breast cancer who have received at least two prior systemic therapies for metastatic disease. HR-positive/HER2-negative Metastatic Breast Cancer: The medicine is indicated for the treatment of hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) metastatic breast cancer (mBC) in patients who have received two or more prior systemic therapies. Metastatic Urothelial Cancer (mUC): Trodelvy is also approved for patients with locally advanced or metastatic urothelial cancer who have previously received a platinum-containing chemotherapy and either a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor.

Dosage and Administration: Trodelvy is administered intravenously under the supervision of a healthcare professional (HCP). The recommended dosage and treatment regimen may vary depending on the type of cancer being treated and the patient's individual characteristics.

Trodelvy is typically administered at a recommended dosage of 10 mg/kg via intravenous infusion once weekly, specifically on Days 1 and 8 within a 21-day treatment cycle. Treatment should be continued until disease progression or if any adverse reactions become unacceptable. It's essential not to exceed the recommended dosage of 10 mg/kg. Close monitoring for potential adverse reactions is essential during treatment with Trodelvy.

How Trodelvy Works: Trodelvy utilizes a two-part mechanism of action to target and destroy cancer cells:

Targeted Delivery: The monoclonal antibody component of Trodelvy binds specifically to the Trop-2 receptor, which is overexpressed on the surface of cancer cells. This targeting mechanism allows Trodelvy to selectively deliver the attached chemotherapy payload to cancer cells while sparing healthy tissues.

Chemotherapy Payload: Once bound to the Trop-2 receptor, Trodelvy is internalized by the cancer cell, releasing its payload of the chemotherapy drug, SN-38. SN-38 is a potent inhibitor of topoisomerase I, an enzyme essential for DNA replication and cell division. By inhibiting topoisomerase I, SN-38 induces DNA damage and ultimately leads to cancer cell death.

Clinical Efficacy: Clinical trials evaluating Trodelvy have demonstrated promising results in patients with metastatic triple-negative breast cancer and metastatic urothelial cancer. In a pivotal Phase 3 trial in mTNBC, Trodelvy significantly prolonged progression-free survival and overall survival compared to standard chemotherapy. Similarly, in a Phase 2 trial in mUC, Trodelvy showed durable responses and favorable survival outcomes in patients who had previously received platinum-based chemotherapy and immunotherapy.

Side Effects: While Trodelvy offers significant therapeutic benefits, it can also cause side effects. Common side effects associated with Trodelvy may include: Neutropenia: Treatment with this medication can cause a decrease in white blood cell counts, specifically neutrophils, which can increase the risk of infection. Diarrhea: Gastrointestinal symptoms such as diarrhea may occur and should be managed promptly to prevent dehydration. Nausea and Vomiting: Some patients may experience nausea and vomiting during treatment with Trodelvy. Fatigue: Fatigue or weakness may occur as a result of treatment.

It is essential for patients to communicate any side effects or symptoms to their healthcare provider promptly.

Precautions and Considerations: While Trodelvy offers significant therapeutic benefits, it is essential to consider precautions and potential risks associated with its use. Patients receiving Trodelvy should be monitored closely for adverse reactions, including: Hepatotoxicity: Trodelvy can cause liver damage, as indicated by elevated liver enzymes. Liver function tests should be performed regularly, and patients with pre-existing liver conditions should be closely monitored. Interstitial Lung Disease (ILD): ILD, including pneumonitis, can occur with Trodelvy treatment. Patients should report any new or worsening respiratory symptoms, such as cough or difficulty breathing, to their healthcare provider promptly. Pregnancy and Breastfeeding: Trodelvy can harm an unborn baby and should not be used during pregnancy. Women of childbearing age should use effective contraception during treatment and avoid breastfeeding.

It is crucial for healthcare providers to assess patients' medical history and closely monitor for potential complications during Trodelvy treatment. Patients should be educated about the importance of reporting any adverse reactions or symptoms to their healthcare provider promptly. By carefully considering precautions and taking appropriate measures, patients and healthcare providers can maximize the benefits of Trodelvy while minimizing risks.

Cost of Trodelvy: At present, Trodelvy (sacituzumab govitecan) is not currently available in India. However, it's important to note that prices can fluctuate based on variables such as dosage and treatment duration. For the most accurate and current information regarding the cost of Trodelvy in India, Patients, Doctors, and Hospitals are encouraged to reach out to Indian Pharma Network (IPN) via Call/WhatsApp: +91 9310090915.

Conclusion: Trodelvy represents a significant advancement in the treatment of breast cancer and urothelial cancer, offering a targeted and effective therapy for patients who have progressed on standard treatments. By understanding the indications, mechanism of action, clinical efficacy, and potential side effects associated with Trodelvy, patients and healthcare providers can make informed decisions about treatment options and optimize patient outcomes. Continued research and clinical trials will further elucidate the role of Trodelvy in the evolving landscape of cancer therapy.

Reference:

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Trodelvy for Breast Cancer

Trodelvy (sacituzumab govitecan) 180 MG Vial in India

Looking to buy Trodelvy 180 mg vial in India? Indian Pharma Network offers access to Trodelvy through the Named Patient Program. As a trusted supplier, we ensure seamless procurement of the best-quality Trodelvy 180 mg vials for patients in need. Trodelvy is a vital treatment option for various conditions, and our dedicated team assists in navigating the procurement process. With our expertise and commitment to patient care, we provide reliable access to Trodelvy, helping individuals receive the treatment they require. With our expertise and commitment to patient care, Indian Pharma Network strives to provide access to life-saving medications, making a difference in the lives of those battling cancer. Contact us today via Call/WhatsApp: +91 9310090915 to learn more about how we can assist you in obtaining Trodelvy through the Named Patient Program.

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Trodelvy is used for treating HR+/HER2-metastatic breast cancer, metastatic triple-negative breast cancer (mTNBC), and advanced bladder cancer. Buy Trodelvy 180 mg online at the best price from Indian Pharma Network. We offer convenient access to this life-saving medication, ensuring that patients can receive the treatment they need without any hassle. Trodelvy is a crucial medication used in the treatment of certain types of cancer, and we understand the importance of making it accessible to all who need it. With our streamlined online platform, patients can easily purchase Trodelvy 180 mg and have it delivered directly to their doorstep. Our commitment to quality and affordability ensures that patients receive genuine medications at competitive prices. Trust Indian Pharma Network for all your medication needs and experience unparalleled convenience and reliability in procuring Trodelvy and other essential medications. Kindly connect with us today via Call/WhatsApp: +91 9310090915.

Trodelvy 180 MG (sacituzumab govitecan) Injection in India

Trodelvy (sacituzumab govitecan-hziy) 180 mg injection is a therapeutic drug used for the treatment of HR+/HER2-metastatic breast cancer, metastatic triple-negative breast cancer (mTNBC), and advanced bladder cancer. Trodelvy 180 mg injection works by targeting and delivering chemotherapy directly to cancer cells, helping to slow down or stop their growth. Trodelvy is administered intravenously by a healthcare professional and is typically given once every two weeks. Common side effects may include nausea, fatigue, diarrhea, decreased appetite, and hair loss. It is important to discuss the potential benefits and risks of Trodelvy with your healthcare provider before starting treatment. Trodelvy has shown promising results in clinical trials and may offer hope for patients with metastatic triple-negative breast cancer. Please Call/WhatsApp: +91 9310090915 to buy Trodelvy injection legally.

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Trodelvy for Patients in India: What You Need To Know

Introduction:

Trodelvy (sacituzumab govitecan-hziy) is a medication prescribed for specific cancer types. Administered intravenously, it's typically infused as a solution mixed from a powder, given on days 1 and 8 within a 21-day treatment cycle for adults with certain cancers in specific scenarios. Trodelvy is used in adults to treat the following cancers in certain situations:

Triple-negative breast cancer (TNBC)

HR-positive, HER2-negative breast cancer

urothelial cancer (cancers affecting the urinary tract, such as certain bladder cancers)

Sacituzumab govitecan-hziy is the key component of Trodelvy, a member of the antibody-drug conjugate drug class. As a biologic medication, Trodelvy is derived from living cells, distinguishing it from traditional chemical-based drugs.

Trodelvy (sacituzumab govitecan-hziy) for Indian Patients: Sacituzumab govitecan, an FDA-approved therapeutic drug, combines a Trop-2-directed antibody with a topoisomerase inhibitor drug conjugate. With 3 established indications, it's a recommended treatment by oncologists for metastatic triple-negative breast cancer, HR-positive, HER2-negative breast cancer, and metastatic urothelial cancer. Gilead Sciences developed and promotes this therapeutic drug, known by its brand name Trodelvy, with a commercially available strength of 180 mg per vial.

Sacituzumab or Trodelvy in India is not readily accessible from local pharmacies or oncology centers. This is because the medicinal product is yet to be locally registered. However, Indian patients have an official provision called the Named Patient Program (NPP) through which patients can procure the medication. The internationally authorized commercial vials can be sourced on behalf of medical advice. Oncologists are known to prescribe specialized medicines for various approved indications even though they are not promptly available. Patients can readily source or procure those medications by applying for the relevant permits from India.

Access Trodelvy (sacituzumab govitecan-hziy) in India: Professional Guidance If you're an Indian patient looking for Trodelvy 180 mg price in India, the Indian Pharma Network (IPN) is here to help. We have years of experience in assisting patients like you with getting advanced medicines such as Sacituzumab govitecan 180 mg in India. Our process is straightforward and ensures that you feel comfortable every step of the way. We'll connect you with trusted sources who can help speed up the import process for your therapeutic drug. We know how important it is to get lifesaving drugs quickly, and our team is dedicated to helping you get the treatment you need as soon as possible.

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Reference: https://www.trodelvy.com/

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Trodelvy: All about the medicine

In recent times, the landscape of cancer treatment has been transmogrified expeditiously, with advanced medicines like Trodelvy (180 mg and 200 mg) offering new expectancy to patients. Trodelvy, also known as sacituzumab govitecan, is a groundbreaking medicine that has shown remarkable efficacy in treating certain types of cancer. In this article, we will delve into indications, dosage, administration, side effects, and Trodelvy injection price in India.

Indication: Trodelvy is primarily used for the treatment of metastatic triple-negative breast cancer (mTNBC), HR+/ HER2- metastatic breast cancer, and locally advanced or metastatic urothelial cancer (mUC). mTNBC is a type of breast cancer that lacks estrogen, progesterone, and HER2 receptors, making it difficult to treat with traditional therapeutic options. Trodelvy has shown promise in treating patients with metastatic urothelial cancer.

Dosage and Administration: The proposed dosage of Trodelvy injection is 10 mg/kg administered intravenously (IV) on days 1 & 8 of a 21-day cycle until disease progression or the occurrence of unacceptable toxicity. The dosage of Trodelvy may be adjusted on behalf of individual patient factors. Proper administration of medication by a health specialist is necessary to ensure its effectiveness.

Side Effects of Trodelvy: Like most medicines, Trodelvy 180 mg or 200 mg comes with potential side effects. The most common side effects of Trodelvy include fatigue, nausea, diarrhea, anemia, and neutropenia. It is advised for all patients to communicate openly with their health specialists about any side effects they experience, as there are ways to tackle and mitigate them.

Trodelvy Price in India: The price of Trodelvy in India can vary on behalf of factors such as the dosage required and the patient's location. Generally, specialty cancer medicines like Trodelvy tend to be expensive due to research and development costs. Kindly contact THE INDIAN PHARMA directly via TOLL-FREE: 1800-889-1064 or Call or WhatsApp: +91 9310090915 or check The Indian Pharma's official website for the most up-to-date information on Trodelvy injection price.

Conclusion: In conclusion, Trodelvy represents a significant advancement in the treatment of rmTNBC, HR+/ HER2- metastatic breast cancer, and metastatic urothelial cancer (mUC). While it offers effective outcomes, it is recommended for patients to consult their doctors to determine if it is the right therapeutic option for them. With current research as well as development in the segment of oncology, we can expect more breakthroughs like Trodelvy in the future, offering renewed hope to cancer patients across the world.

Reference: https://www.trodelvy.com/

[trodelvy]

Trodelvy: A Lifesaving Therapy for TNBC Available Across South Asia

Trodelvy, known scientifically as sacituzumab govitecan-hziy, is an innovative targeted therapy specifically approved for treating certain types of breast cancer, particularly triple-negative breast cancer (TNBC) that has metastasized or become inoperable. It is classified as an antibody-drug conjugate (ADC), a class of drugs that combines an antibody targeting cancer cells with a potent chemotherapy agent. This unique mechanism allows Trodelvy to deliver chemotherapy directly to cancer cells, significantly reducing damage to surrounding healthy tissues. Additionally, Trodelvy price in India is competitive, ensuring accessibility for a broader range of patients.

Mechanism of Action

Trodelvy targets Trop-2, a protein overexpressed in many solid tumors, including over 80% of breast cancers. The drug is engineered with a pH-sensitive linker that releases the cytotoxic agent, SN-38, once inside the cancer cell. This targeted approach not only enhances the treatment's efficacy but also reduces systemic side effects compared to traditional chemotherapy, offering a more precise attack on cancerous cells while sparing healthy tissues.

Indications and Usage

Trodelvy is primarily indicated for patients with metastatic TNBC who have already undergone at least two prior therapies, including one specifically for metastatic disease. It has also shown promise in treating other malignancies, such as urothelial carcinoma, in clinical trials. The treatment is administered intravenously, typically following a schedule of once a week for two consecutive weeks, followed by a week off, in a repeating 21-day cycle.

Efficacy Statistics

Clinical trials have demonstrated the significant efficacy of Trodelvy. In the ASCENT trial, focused on patients with metastatic TNBC, the overall response rate (ORR) was 31%, with 12% of patients experiencing complete responses. In a separate phase 2 clinical trial for bladder cancer, Trodelvy showed a response rate of 27.7%, with 22.3% of patients experiencing a reduction in tumor size of at least 30%. Moreover, 5.4% of participants had their tumors completely disappear, with a median duration of response lasting 7.2 months.

Trodelvy, a groundbreaking therapy for treating triple-negative breast cancer (TNBC), offers new hope for patients with metastatic or inoperable cases. Known for its targeted action, Trodelvy is now accessible across South Asia, including Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka. With a competitive Trodelvy price, this life-saving medication is more widely available to those in need.

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Buy Trodelvy 180 mg Injection at Lowest Price from India

Trodelvy 180 mg for injection is designed to carry cancer-fighting drug to cells that have Trop-2 proteins. Certain tumor cells have high Trop-2 proteins. The medicine trodelvy 180 mg injection is approved for 3 different types of cancer:

Advanced Bladder Cancer

HR+/HER2- Metastatic Breast Cancer

Metastatic Triple Negative Breast cancer Trodelvy injection 180 mg is a type of antibody-drug conjugate (ADC) treatment that is designed to work differently than traditional chemotherapy. It is designed to deliver promising anticancer drug directly into cells with Trop-2 proteins. Make an inquiry either via TOLL-FREE: 1800-889-1064, or Call/WhatsApp: +919310090915 and we will help you compute the total price to buy Trodelvy (sacituzumab govitecan) for injection online at the best price and have it delivered to your location. From your side, we’ll only need a valid prescription from your treating physician. In some countries, we might also ask for an import license.

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Trodelvy for Breast Cancer

TRODELVY is a cancer drug which is used in the treatment of adults suffering from locally advanced or metastatic triple-negative breast (mTNBC) cancer and locally advanced or metastatic urothelial cancer (mUC). It is a trop-2-directed antibody and topoisomerase inhibitor conjugate drug used at prescribed and recommended doses according to body weight. It is given intravenously only, and the Trodelvy injection price is economical, and it can be bought by any recognized supplier. It is given in the vein by drip on day 1 and day 8 of the repeating 3-week cycle. Treatment may be continued for as long as it remains effective. It has the active ingredient, Sacituzumab govitecan, which is responsible for the action of Trodelvy by attaching to the antibody by the linker.

TRODELVY: Dosage and Administration It comes as 180 mg lyophilized powder in single-dose vials for reconstitution to be given intravenously. It is given on the basis of weight, and the recommended dose is 10 mg/kg, administered as an IV infusion once weekly. It is also available in 200mg vials, and we supply TRODELVY 200 mg vials at Ikris against a valid prescription. Before administering Trodelvy, antipyretic medication is given to the patient to induce nausea and vomiting, which are caused due to an infusion reaction. Antipyretic drugs act as H1 and H2 blockers, and those who have prior infusion reactions are given corticosteroids. After premedication, Trodelvy is given for 3 hours intravenously; during and after 30 minutes, any kind of infusion-related reactions are observed.

TRODELVY: Availability In India Trodelvy has been compared with standard treatment in one of the main studies, which had 529 patients with metastatic or locally advanced triple-negative breast cancer who received two or more prior systemic (whole-body) treatments, including at least one of them for advanced disease. Patients who took Trodelvy lived for an average of 4.8 months without cancer progression and getting it worse than as compared with 1.7 months for the patients who took standard treatment. Patients on Trodelvy lived for an average of 11.8 months compared with 6.9 months for patients on standard treatment. Trodelvy is available in India through various generic medication suppliers and the TRODEDLVY injection price in India is pocket-friendly, and anyone with a prescription can purchase it easily.

TRODELVY: Mechanism of action The active pharmaceutical ingredient in Trodelvy is Sacituzumab govitecan-hziy which consists of two active components that are a monoclonal antibody ( which is a kind of protein ) that has been linked to a small molecule, SN-38. The monoclonal antibody has been made to recognize and attach to Trop-2(a kind of protein in many breast cancer cells). When it is attached, and the drug is used up by the cell, then SN-38 becomes active. SN-38 is a cancer medicine that belongs to the group topoisomerase inhibitors. It blocks an enzyme called topoisomerase I, which is involved in copying cell DNA needed to make new cells. By blocking the enzyme, cancer cells are prevented from multiplying and eventually die. Trodelvy's benefits are greater than its risks; that's why it is approved by FDA, and anyone with a prescription can buy trodelvy in India.

TRODELVY: Adverse Drug Reaction Like any other medication, it comes with some undesired side effects. The most common side effect caused by taking Trodelvy is diarrhea, Nausea (feeling of being sick), low count of neutrophils( they are a kind of WBC which help to fight against infection), loss of hair which is called alopecia, anaemia ( low levels of haemoglobin, causes pale skin and tiredness ). These common ADRs affect more than 1 in 5 people who are undergoing the treatment. Other common side effects include loss of appetite, constipation, cough, belly pain and vomiting. Vomiting and Nausea can also occur during the time of infusion, so to prevent these, antipyretics are given as premedication. The most common serious side effects are febrile neutropenia which is low white blood cell counts with fever due to infection and diarrhea. Well, this medication is all safe to use and is FDA approved. Moreover, the cost of Trodelvy in India is economical and budget-friendly, and it should be used under the influence of expert medical supervisors of its speciality.

TRODELVY: Measures to ensure safe and effective use While preparing in an infusion bag, a sterile syringe is used in order to preserve aseptic practice and make the preparation safe from any kind of contamination. Do not shake, but gently swirl. It is light-sensitive, so it needs to be protected from light and must be stored in cool and shady places. After mixing, if there is any precipitation or cloudy substance forming, don't use the preparation and discard it. As for all medicines, data on the use of Trodelvy are continuously monitored. Predicted side effects reported with Trodelvy are carefully evaluated, and any necessary action is taken to protect patients. One can ask his pharmacist or healthcare provider for information about TRODELVY that is written for health professionals. During intravenous infusion, too, the patient must be carefully observed. Trodelvy injections are available, and the cost of trodelvy injection is budget friendly as compared to other medications of the same line.

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All About Trodelvy

Handling and Disposal: Trodelvy, often referred to as sacituzumab govitecan-hziy, comes in two doses: 180 mg and 200 mg. This medication is supplied in single-dose vials that are colored off-white to yellowish due to freeze-drying. Every vial is packaged separately within a carton. Included is one 180 mg vial with the NDC 55135-132-01 packaging code. It is imperative that these vials be kept in their respective containers and refrigerated between 2 and 8 degrees Celsius. There should never be a freeze on the medication. Because trodelvy can cause harm, it must be handled and disposed of with caution. Numerous Trodelvy Side effects, including as anemia, lethargy, baldness, decreased appetite, coughing, nausea, vomiting, and diarrhoea, can also arise from trodelvy therapy.

Medication For Breast Cancer: Trodelvy is a crucial part of the treatment of metastatic triple-negative breast cancer (mTNBC). The active component that provides the therapeutic effects of trodelvy is sacituzumab govitecan. Both the specific protein and the monoclonal antibody that comprise this medication are necessary ingredients. Its primary benefits are for patients who have had at least two previous treatments for metastatic disease. Trodelvy is performed when surgical removal of the cancerous tissue is not feasible. The main medicinal ingredient is sacituzumab govitecan-hziy, which is a mix of a Trop-2-directed antibody and a topoisomerase inhibitor. It is important to keep in mind that Trodelvy can only be prescribed by licensed medical professionals. To buy trodelvy in India and make it accessible to a wider community,

Available as lyophilized powder: Trodelvy must be given in accordance with FDA-approved cycles, and the dosage is directly correlated with the patient's body weight. An intravenous dose of 10 mg/kg is given twice a day, on the first and the eighth day of each repeating 21-day cycle. Sacituzumab govitecan-hziy must be dosed accurately based on the patient's weight because it is a lyophilized powder. To create a concentration of 10 mg/mL, the vial is mixed with 20 mL of 0.9% sodium chloride injection, USP.Trodelvy 180mg is a reasonably priced medication that is readily accessible in the market

Use In Chemotherapy: As part of the treatment regimen, a 5-HT3 receptor antagonist or an NK1 receptor antagonist is given as a premedication along with dexamethasone. This premedication approach lessens the chance that infusion reactions and chemotherapy will cause nausea and vomiting. The reason Trodelvy is so reasonably priced in India is its unique blend of a topoisomerase inhibitor and an anti-Trop-2 antibody. In individuals who have not responded well to earlier infusions, corticosteroids should be given. For additional information on the trodelvy cost , get in touch with Indian Pharma, a licensed distributor of this drug.

Potency of The Drug : Trodelvy offers hope to patients with advanced triple-negative breast cancer who have undergone at least two prior therapies. What makes it successful is how it interacts with SN-38, a small molecule that is crucial to its mode of action. The drug's potency is further increased by Trodelvy's monoclonal antibody's ability to bind to the Trop-2 protein present on a range of breast cancer cells. An additional advantage of Trodelvy is its cost-effectiveness, which is made possible by Indian Pharma. For individuals who would like additional information regarding the Trodelvy price. Along with anemia, more than one in five patients undergoing therapy for metastatic triple-negative breast cancer may also experience baldness, decreased appetite, coughing, stomach discomfort, and exhaustion.

Use Under Prescription: One of the potential negative effects of Trodelvy treatment is the emergence of severe or possibly fatal neutropenia. It is necessary to temporarily halt the administration of trodelvy in patients who have neutropenic fever or an absolute neutrophil count below 1500/mm3. It is essential to regularly evaluate blood cell counts during the course of treatment. It makes sense to utilize G-CSF for secondary prevention. In patients with feverish neutropenia, anti-infective treatment ought to be initiated promptly. It's crucial to remember that the cost of Trodelvy injection is reasonably priced and accessible for those who have a valid prescription.

Therapeutic Effects : The active component of Trodelvy that promotes its therapeutic effects is sacituzumab govitecan-hziy. Inactive ingredients in trodelvy include trehalose dihydrate, polysorbate 80, and 2-(N-morpholino) ethane sulfonic acid. 180 mg and 200 mg are the available strengths. Sacituzumab govitecan-hziy has shown promise in treating progesterone- and oestrogen-receptor-negative breast cancer because of its mechanism of action.For those who want to buy Trodelvy from India at a discount,

Negative Reactions: Those who have previously experienced a significant negative reaction to trodelvy shouldn't use it. There is a chance of serious hypersensitivity reactions with sacituzumab govitecan-hziy, including potentially lethal anaphylactic reactions. A few of the reactions that could happen are hypotension, wheezing, angioedema, swelling, pneumonitis, and skin reactions. To lessen the effects of the infusion, premedication is recommended. It's also advisable to have an emergency supply of medications and supplies on hand to manage any potential infusion-related complications, such as anaphylaxis, when administering sacituzumab govitecan-hziy. For more information on trodelvy injection price in India.

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Trodelvy for Breast Cancer

Trodelvy, also known as sacituzumab govitecan-hziy, is available in 180 mg and 200 mg dosages. Because of freeze-drying, this drug is delivered in single-dose vials that range in color from off-white to yellowish. Each vial is individually wrapped in a carton. One 180 mg vial with the packing code NDC 55135-132-01 is included. These vials must be stored in their original containers and chilled between 2 and 8 degrees Celsius. The drug shouldn't ever be frozen. Trodelvy needs to be handled and disposed of carefully because it can be harmful. Trodelvy therapy can also result in a variety of side effects, such as anemia, fatigue, baldness, decreased appetite, coughing, nausea, vomiting, and diarrhea.

Trodelvy is an essential component of triple-negative breast cancer (mTNBC) treatment for metastatic disease. Sacituzumab govitecan is the active ingredient that gives trodelvy its medicinal effects. The monoclonal antibody and the particular protein that make up this drug are essential components. Patients who have received at least two prior therapies for metastatic illness are the main beneficiaries of this treatment. When it is not possible to remove the malignant tissue surgically, trodelvy is used.Remember that only authorized medical experts are permitted to prescribe Trodelvy. To buy trodelvy in India and provide access to a larger population, contact Indian Pharma Network.

Trodelvy dosages are based on the patient's body weight and must be administered in compliance with FDA-approved cycles. Every repeating 21-day cycle, an intravenous dose of 10 mg/kg is administered twice a day, on the first and eighth day. Since sacituzumab govitecan-hziy is a lyophilized powder, dosage must be precisely determined by the patient's weight. The vial is combined with 20 mL of 0.9% sodium chloride injection, USP, to achieve a concentration of 10 mg/mL.Indian Pharma Network provides a fairly costly Trodelvy 180mg, which is easily accessible on the market.

A 5-HT3 receptor antagonist or an NK1 receptor antagonist is prescribed as a premedication in addition to dexamethasone as part of the therapy protocol. This premedication strategy reduces the likelihood of nausea and vomiting from chemotherapy and infusion responses. Trodelvy's special combination of an anti-Trop-2 antibody and a topoisomerase inhibitor accounts for its low cost in India. Corticosteroids should be administered to people whose prior infusions did not go well.Contact Indian Pharma Network a certified distributor of this medication, for more details on the rodelvy cost.

Patients with advanced triple-negative breast cancer who have received at least two prior therapy have hope with trodelvy. Its interaction with SN-38, a tiny molecule essential to its method of action, is what makes it effective. Trodelvy's monoclonal antibody's capacity to bind to the Trop-2 protein found on a variety of breast cancer cells contributes to the drug's efficacy. Trodelvy's affordability, which is made possible by Indian Pharma Network, is an added benefit. For those who are interested in learning more about the Trodelvy price. More than one in five patients with metastatic triple-negative breast cancer who are receiving medication may also have baldness, decreased appetite, coughing, stomach discomfort, and tiredness in addition to anemia.

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Trodelvy Injection: A Game-Changer in Cancer Care

Trodelvy contains the active pharmaceutical ingredients sacituzumab govitecan. The medicine is used for the treatment of patients with triple-negative breast cancer (TNBC), HR+/HER2- metastatic breast cancer, and advanced bladder cancer. If you are searching for a genuine Trodelvy supplier from India, then Indian Pharma Network (IPN) can be your most reliable source/platform. IPN is WHO GDP & ISO 9001 2015 Certified Trodelvy Supplier, Wholesaler, Importer, and Exporter from India. Trodelvy which is Manufactured by Gilead Sciences, Inc, is available in a strength of 180 mg/mL. Trodelvy 180 mg is supplied for Tenders/ exports/ imports/ Named patient program/ RLD supplies/ Reference listed drugs/ Comparator Drug/ Bio-Similar/ Innovator samples for Clinical trials. Indian Pharma Network is the legitimate source of Trodelvy (sacituzumab govitecan-hziy) for injection, all the customers can get in touch with us to buy/order/procure this pharmaceutical product in approved quantity.

Buy Trodelvy 180 mg Injection at Lowest Price from India

Trodelvy 180 mg for injection is designed to carry cancer-fighting drug to cells that have Trop-2 proteins. Certain tumor cells have high Trop-2 proteins. The medicine trodelvy 180 mg injection is approved for 3 different types of cancer:

Advanced Bladder Cancer

HR+/HER2- Metastatic Breast Cancer

Metastatic Triple Negative Breast cancer Trodelvy injection 180 mg is a type of antibody-drug conjugate (ADC) treatment that is designed to work differently than traditional chemotherapy. It is designed to deliver promising anticancer drug directly into cells with Trop-2 proteins.

Buy Trodelvy in India I Sacituzumab Govitecan 180 MG Vial

Trodelvy (sacituzumab govitecan) is a type of medicinal product known as antibody-drug conjugate, or ADC for short. Unlike typical (traditional) chemotherapy, ADCs consist of three parts: an antibody, an anticancer medicine, and a linker. If you want to buy trodelvy in India for triple-negative breast cancer, HR+/HER2- metastatic breast cancer, and advanced bladder cancer, then Indian Pharma Network (IPN) can be your one-stop solution.

We are famed and esteemed in the pharmaceutical industry for our best quality service, vast industry experience, market credentials, and timely delivery. Our all the tie-ups and sourcing from the reputed brands allow us to offer the best price for Trodelvy 180 mg vial. Trodelvy (sacituzumab govitecan 180 mg vial) is an intravenous (IV) infusion (10mg/kg). Proposed doses are administered once weekly for two weeks (Day 1 and 8) of 21-day treatment cycles. Each treatment cycle is 21 days (3 weeks).

Sacituzumab Govitecan- Trodelvy Price for 180 MG Vial in India

Trodelvy is made of two different drugs joined together: a monoclonal antibody drug (which attaches to Trop -2 receptors, present on the outside of some cancer cells, and a chemotherapy drug (which stops all cells including unhealthy cells from growing and dividing). The monoclonal antibody drug attaches to the unhealthy cells and then releases the chemotherapy medicine directly into the cell. All pharmaceutical products – comparator drugs, adjunctive therapies, RLDs, co-meds and rescue meds, and Exports/Imports drugs – are transported in standard temperature-controlled conditions with active monitoring in order to ensure the integrity of products. Contact us today to get/buy your hard-to-access prescription medicine at the lowest price from India.

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Trodelvy in India: Accessing Essential Cancer Treatment

Trodelvy (sacituzumab govitecan-hziy) is a breakthrough trop-2-directed antibody and topoisomerase inhibitor conjugate available in 180 mg lyophilized powder vials for intravenous use.

Can I buy Trodelvy in India legally? Yes, you can buy Trodelvy online in India through the Indian Pharma Network (IPN). Although the drug is not yet approved locally, IPN facilitates its import from certified international suppliers, ensuring safe and legal access for Indian patients.

What cancers does Trodelvy treat? Trodelvy is approved for treating: Advanced or metastatic triple-negative breast cancer (mTNBC) Advanced or metastatic hormone receptor-positive, HER2-negative breast cancer Locally advanced or metastatic urothelial cancer (mUC)

How does the Indian Pharma Network (IPN) help patients access Trodelvy? IPN specializes in sourcing and delivering Trodelvy 180 mg injections for patients, doctors, and hospitals. With their expertise, they ensure the process is seamless, legal, and efficient.

Can I get Trodelvy in smaller towns in India? Yes, IPN provides Trodelvy to patients in smaller cities like Varanasi, Kanpur, Patna, Guwahati, Tirupati, Visakhapatnam, and more. No matter your location, IPN ensures prompt delivery of the medicine.

How can I contact IPN to buy Trodelvy in India? To buy Trodelvy in India and beyond, contact Indian Pharma Network (IPN) via: Call/WhatsApp: +91 9310090915 TOLL-FREE Number: 1800-889-1064 IPN ensures that life-saving treatments like Trodelvy are within reach for patients, providing hope and healing when it matters the most.

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Trodelvy Warnings & Precautions

Trodelvy (sacituzumab govitecan-hziy) is a therapeutic medicine used for the treatment of patients with HE+Ve/HER2-Ve metastatic breast cancer, metastatic triple-negative breast cancer (mTNBC), and locally advanced or metastatic urothelial cancer (mUC). Trodelvy is commercially available in 180 mg and 200 mg dosage strengths. While this medicine can be a promising therapy, it's necessary to know potential warnings and precautions related to its use:

Neutropenia: Trodelvy 180 mg/200 mg vials may be responsible for causing a reduction in WBC counts, specifically neutrophils, which can enhance the risk of infections. Regular blood tests are necessary to monitor these levels.

Diarrhea: Critical diarrhea can occur with the use of Trodelvy therapy. Individuals need to take anti-diarrheal medicines and follow their doctor's instructions to effectively manage diarrhea.

Interactions: Let your clinician know about all medicines, supplements, and herbal products you are using, as Trodelvy treatment may interact with other medicines.

Pregnancy and Nursing: Trodelvy injection can be responsible for harm to an unborn baby, so it's important to avoid pregnancy during therapy and use promising birth control. It's also advisable to avoid breastfeeding.

Infusion Reactions: Infusion-related reactions may occur during treatment. Doctors are prepared to manage infusion reactions in a medical setting.

Liver Function: Trodelvy 200 mg/180 mg vials can be responsible for affecting liver function, so regular liver function tests are crucial throughout treatment.

Hematologic Toxicity: This medicine may cause thrombocytopenia and anemia, which require precise monitoring as well as management.

Interstitial Lung Disease (ILD): ILD is a rare but critical lung complication that has been reported with Trodelvy treatment. Report promptly in case of any new or worsening respiratory signs and symptoms.

Hypersensitivity Reactions: Seek prompt medical attention in case of signs of hypersensitivity, such as chills, fever, or difficulty breathing.

Note: Always follow your doctor's recommendations and report any unusual signs and symptoms or adverse reactions immediately when using Trodelvy injection. This information is for general purpose; consult your doctor and medicine label for comprehensive information and personalized guidance.

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Trodelvy: Uses, Dosage, Side Effects, Warnings

Handling and Disposal: Trodelvy, often referred to as sacituzumab govitecan-hziy, comes in two doses: 180 mg and 200 mg. This medication is supplied in single-dose vials that are colored off-white to yellowish due to freeze-drying. Every vial is packaged separately within a carton. Included is one 180 mg vial with the NDC 55135-132-01 packaging code. It is imperative that these vials be kept in their respective containers and refrigerated between 2 and 8 degrees Celsius. There should never be a freeze on the medication. Because trodelvy can cause harm, it must be handled and disposed of with caution. Numerous Trodelvy Side effects, including as anemia, lethargy, baldness, decreased appetite, coughing, nausea, vomiting, and diarrhoea, can also arise from trodelvy therapy. broken image

Medication For Breast Cancer: Trodelvy is a crucial part of the treatment of metastatic triple-negative breast cancer (mTNBC). The active component that provides the therapeutic effects of trodelvy is sacituzumab govitecan. Both the specific protein and the monoclonal antibody that comprise this medication are necessary ingredients. Its primary benefits are for patients who have had at least two previous treatments for metastatic disease. Trodelvy is performed when surgical removal of the cancerous tissue is not feasible. The main medicinal ingredient is sacituzumab govitecan-hziy, which is a mix of a Trop-2-directed antibody and a topoisomerase inhibitor. It is important to keep in mind that Trodelvy can only be prescribed by licensed medical professionals. To buy trodelvy in India and make it accessible to a wider community, get in touch with The Indian Pharma.

Available as lyophilized powder: Trodelvy must be given in accordance with FDA-approved cycles, and the dosage is directly correlated with the patient's body weight. An intravenous dose of 10 mg/kg is given twice a day, on the first and the eighth day of each repeating 21-day cycle. Sacituzumab govitecan-hziy must be dosed accurately based on the patient's weight because it is a lyophilized powder. To create a concentration of 10 mg/mL, the vial is mixed with 20 mL of 0.9% sodium chloride injection, USP. Trodelvy 180mg is a reasonably priced medication that is readily accessible in the market

Use In Chemotherapy: As part of the treatment regimen, a 5-HT3 receptor antagonist or an NK1 receptor antagonist is given as a premedication along with dexamethasone. This premedication approach lessens the chance that infusion reactions and chemotherapy will cause nausea and vomiting. The reason Trodelvy is so reasonably priced in India is its unique blend of a topoisomerase inhibitor and an anti-Trop-2 antibody. In individuals who have not responded well to earlier infusions, corticosteroids should be given. For additional information on the trodelvy cost , get in touch with Indian Pharma, a licensed distributor of this drug.

Potency of The Drug : Trodelvy offers hope to patients with advanced triple-negative breast cancer who have undergone at least two prior therapies. What makes it successful is how it interacts with SN-38, a small molecule that is crucial to its mode of action. The drug's potency is further increased by Trodelvy's monoclonal antibody's ability to bind to the Trop-2 protein present on a range of breast cancer cells. An additional advantage of Trodelvy is its cost-effectiveness, which is made possible by Indian Pharma. For individuals who would like additional information regarding the Trodelvy price. Along with anemia, more than one in five patients undergoing therapy for metastatic triple-negative breast cancer may also experience baldness, decreased appetite, coughing, stomach discomfort, and exhaustion.

Use Under Prescription: One of the potential negative effects of Trodelvy treatment is the emergence of severe or possibly fatal neutropenia. It is necessary to temporarily halt the administration of trodelvy in patients who have neutropenic fever or an absolute neutrophil count below 1500/mm3. It is essential to regularly evaluate blood cell counts during the course of treatment. It makes sense to utilize G-CSF for secondary prevention. In patients with feverish neutropenia, anti-infective treatment ought to be initiated promptly. It's crucial to remember that the cost of Trodelvy injection is reasonably priced and accessible for those who have a valid prescription.

Therapeutic Effects: The active component of Trodelvy that promotes its therapeutic effects is sacituzumab govitecan-hziy. Inactive ingredients in trodelvy include trehalose dihydrate, polysorbate 80, and 2-(N-morpholino) ethane sulfonic acid. 180 mg and 200 mg are the available strengths. Sacituzumab govitecan-hziy has shown promise in treating progesterone- and oestrogen-receptor-negative breast cancer because of its mechanism of action.

Negative Reactions: Those who have previously experienced a significant negative reaction to trodelvy shouldn't use it. There is a chance of serious hypersensitivity reactions with sacituzumab govitecan-hziy, including potentially lethal anaphylactic reactions. A few of the reactions that could happen are hypotension, wheezing, angioedema, swelling, pneumonitis, and skin reactions. To lessen the effects of the infusion, premedication is recommended. It's also advisable to have an emergency supply of medications and supplies on hand to manage any potential infusion-related complications, such as anaphylaxis, when administering sacituzumab govitecan-hziy. For more information on trodelvy injection price in India.