#transgenesis

[sigmaleph]

i feel like the discourse lost something when the standard term in english became 'genetically modified' and not, as is more common in e.g. spanish, 'transgenic'

yes sure transgenesis is actually a narrower concept and not equivalent but. have you considered the potential for people complaining about transgenic soy making your kids transgender.

[badatwebweaving]

Dark Paradise - Lana Del Rey // Without You - Lana Del Rey // Travelling Song - Ryn Weaver // Pinterest // Christmas Kids - Roar // Brief Homage to Pluto - Fabio Pusterla // Transgenesis - Ava Nathaniel Winter // Veeaien Designs // Matilda - Harry Styles // All My Love - Noah Kahan // Asyavlade (TikTok) // Those Beloved Ghosts of Compiano - Paul Mariani // Free - Florence & the Machine // My Journey To The Weed Den - Merchant Ships // Sunset Calm in the Bay of Fundy - William Bradford // A Walk Round the Park - Sandra Lim // Creep - Radiohead // On the Death of Sir Erasmus Philips - Anna Williams // L&M Cigarettes // The Frost - Mitski

[romanceyourdemons]

i have difficulty speaking on the effectiveness of the spanish scifi melodrama-thriller the skin i live in (2011) in the time and culture of its release, because in the thirteen years since its time in theaters the conversation around its core themes has changed significantly. the film clearly attempts to explore questions of violation, identity, and femininity—its gratuitous presentation of sensuality and sexual violence makes this clear enough. however, the key lenses through which it presents these themes are transgenesis and sex reassignment surgery, both familiar practices today but much more exotic and dangerous topics at the time of the film’s release. whether the mere invocation of these concepts truly was enough to send a shiver up a 2011 audience’s spine, i do not know; in any case, the film certainly believes it to be sufficient. although the film roughly shares a premise with the french arthouse horror film eyes without a face (1960)—a plastic surgeon, obsessed with reshaping his severely scarred daughter to the image of beauty he recalls, kidnaps and experiments upon people—eyes without a face (1960) presents an almost claustrophobically tightly woven plot and a well-realized, atmospheric setting to develop and add poignancy to its themes of obsession and dehumanization. by contrast, this film relies on the mere invocation of vaginoplasty and genetic research to do that work, allowing its plot to meander soap opera-like and its sense of time and place to scatter. apart from a laser-intense performance by antonio banderas, much of what the film’s tone and critic’s reactions imply to be gut-churning horror has melted away with the years, leaving only its framework of transphobia, misogyny, and camp exposed and reminiscent almost of the assignment (2016). although i can see and reconstruct what the skin i live in (2011) is attempting to do, its reliance on period-specific shock factor undercuts it, leaving a film that feels unrealized, numbing where it seeks to thrill

[ell-if-i-know]

transgenesis more like transGENDERsis

[minecraftdog]

signing up for classes in my uni doesn't make sense at all... it's all first come first served and I'm never able to sign to what I want because my internet isn't the best 😞 like they took up all the spots in animal transgenesis in the first second 😞😞😞

[sobeksewerrat]

This post reminded me of the transgenesis (is that what it's called again?) au and I love it and have also implemented it SORT OF into some cringy Minecraft fanfic I've been "writing" since 2023

(idk why I have the screenshot with that weird water-y filter though ?? i think I was doom scrolling through some shitty tags and some person thought this was a bad post so they put it in this water filter or smth idkkkk)

anygay HOW ARE YOU

And HAS RAMADAN ARRIVED YET

IDK ANYTHING ABT MINECRAFT BUT SLAY

I AM FINE!!! TODAY IS THE FIRST NIGHT ND TOMORROW IS THE FIRST DAY!!!

[bulkym4]

i’m bulky! (i also go by topher) (she/her) thank you for entering my vortex of good

i mainly post about half-life (and nothing else) i'm pretty predictable!

DO NOT INTERACT IF YOU ARE:

NORMAL (SCURRILOUS)

ORDINARY (SCURRILOUS)

A WHIMSICAL MANGROVE LICH

AN EVIL SHOPKEEP (I STILL DO NOT WANT YOUR WARES)

HEARTRACING, HOMOEROTIC, TRAINSPOTTING, XENOBIOLOGICAL, ABRAHAM LINCOLN, MEDICATED, TRANSGENESIS, OR ANYY OTHER UN-, AN-, THE-, 'S- OR -'LL'D'VE

don't talk to me! i've never felt anxiety but i just really hate people and things and events and whimsy. i don’t do commissions (and i never will!) because i'm bad at art

(DNI /gen racists, sexists, transphobes, homophobes, ableists etc.)

[evoldir]

Fwd: Graduate position: UBonn_Germany.EvoDevoPopGenetics

Begin forwarded message: > From: evoldir@evol.biology.mcmaster.ca > Subject: Graduate position: UBonn_Germany.EvoDevoPopGenetics > Date: 17 November 2024 at 05:40:54 GMT > To: rdmpage@gmail.com > > > > PhD Student in Evolutionary Developmental Biology and Population Genetics > Gompel lab – Bonn Institute for Organismic Biology, University of > Bonn, Germany > > Our lab is interested in the genetic bases of morphological evolution. We > are looking for a PhD student to work on a new project at the crossroads > of Evolutionary Developmental Biology and Population Genetics. The > project aims at identifying genetic determinants in a population of flies > (Drosophila), underlying variation in wing pigmentation. The approach > will combine advanced and quantitative phenotypic analysis, genome-wide > association study, as well as molecular and genetic dissection using > transgenesis. The DFG-funded project will be done in collaboration > with quantitative and population geneticists in Montpellier, France, > and will involve reciprocal visits between both labs. The ultimate goal > of the project is to compare among-species genetic variation explaining > phenotypic evolution (past work from the Gompel lab), to within-species > determinants of comparable variation. > > Recent relevant publications: > Bachem K, Li X, et al. (2024) Science Advances, 10(4):eadl2616. doi: > 10.1126/sciadv.adl2616. > Ling L et al. (2023) Science Advances, 17;9(7):eade6529. doi: > 10.1126/sciadv.ade6529. > Xin Y, Le Poul Y, et al. (2020) Proc Natl Acad Sci U S A, > 10:202004003. doi: 10.1073/pnas.2004003117 > > What we offer: > A 3-year PhD student position starting in spring/summer 2025 > Competitive salary based on 13 TV-L (65%) of German pay scale. > Extensive research opportunities in a dynamic and collaborative > environment at the Bonn Institute for Organismic Biology of the University > of Bonn. > > Your profile: > A Master’s degree in life sciences, with a strong emphasis on molecular > biology and genetics > Experience in genomics and data analysis > Experience working in a wet lab > Excellent written and spoken English > > The research environment: > The University of Bonn is one of the most distinguished and well-networked > research universities in the world and conducts research in fields defined > by the Excellence Strategy. It is one of the eleven German Universities > of Excellence, with the most Clusters of Excellence. It combines an > international and intercultural environment with a strong emphasis on > transdisciplinary research, creating a rich environment for PhD students. > > Please send the following materials to apply: > - Your Master’s degree and transcripts. > - A detailed CV and contact details of two academic referees. > - A one-page cover letter highlighting your motivation and summarising >  your research expertise > > Send your application by e-mail to Nicolas Gompel (gompel@uni-bonn.de) > Applications will be evaluated on a rolling basis, until the position > is filled. > > > Prof. Dr.Nicolas Gompel > > University of Bonn > Bonn Institute for OrganismicBiology (BIOB) > > Meckenheimer Allee 169, 53115 Bonn, Germany > > Tel.: +49 (0)228 734784 ngompel@uni-bonn.de  Lab page > > Nicolas Gompel

[lornabassiswrites]

Glancing back at 2024

Last Monday of the year. I'd be lying if I said this has been an easy one. Aside from the continuously horrific news trickling in from all parts of the globe, 2024 was challenging on a personal and professional level as well.

And yet, I will try to look back with a positive lens. 2024 was the year I finally got my driving license! That same month, I also started querying out my first novel, Transgenesis, to agents all over the English speaking world. I felt ready then and still ended up editing my text about ten times after I started querying (more or less every time I sent out a new query, hum hum). Old habits die hard, but in this case, I made huge improvements so they can keep on dying slowly for now.

2024 was also a year of escapism like none other, with D&D (Dungeons and Dragons) at its core. Whether it was through watching Dimension 20's Fantasy High campaigns on Dropout or playing actual D&D with friends (and strangers), or yet again the most important one of the lot, playing Baldur's Gate 3 on my gaming laptop, this was a year of elves and tieflings and rogues and magic and shenanigans aplenty.

And I can wish nothing more than for that to continue in 2025! It already promises to be a year of change and exciting adventures, and I can't wait to see what the future has in store for me, my friends and family. For now, I'll just say "ta-ra"!

[jhavelikes]

Understanding CRISPR-Cas9’s capacity to produce native overexpression (OX) alleles would accelerate agronomic gains achievable by gene editing. To generate OX alleles with increased RNA and protein abundance, we leveraged multiplexed CRISPR-Cas9 mutagenesis of noncoding sequences upstream of the rice PSBS1 gene. We isolated 120 gene-edited alleles with varying non-photochemical quenching (NPQ) capacity in vivo—from knockout to overexpression—using a high-throughput screening pipeline. Overexpression increased OsPsbS1 protein abundance two- to threefold, matching fold changes obtained by transgenesis. Increased PsbS protein abundance enhanced NPQ capacity and water-use efficiency. Across our resolved genetic variation, we identify the role of 5′UTR indels and inversions in driving knockout/knockdown and overexpression phenotypes, respectively. Complex structural variants, such as the 252-kb duplication/inversion generated here, evidence the potential of CRISPR-Cas9 to facilitate significant genomic changes with negligible off-target transcriptomic perturbations. Our results may inform future gene-editing strategies for hypermorphic alleles and have advanced the pursuit of gene-edited, non-transgenic rice plants with accelerated relaxation of photoprotection.

Multiplexed CRISPR-Cas9 mutagenesis of rice PSBS1 noncoding sequences for transgene-free overexpression | Science Advances

[literaturepublisher23]

Image Journal Submission

Body Image Journal: Image Journal Submission: Authors are requested to submit images in body journal, body imaging journal for publication. Body Image Journal is a scholarly open access Journal that appeals to a broad spectrum of allied professionals from clinical and medical fields up to molecular levels. It comprehensively covers new technologies, applications, issues concerning all major diagnostic methods that provide the latest information in medical and clinical diagnosis as well as machine learning for image reconstruction.

Journal Homepage: https://www.literaturepublishers.org/

Body Image Journal includes articles from various fields. Journal intends to include the topics like Magnetic Resonance Angiography, Spine MRI, General Whole Body MRI imaging, MR Arthrography, Magnetic Resonance Cholangiopancreatography (MRCP) but not limited to the below mentioned areas. Journal accepts images related to Breast MRI, Chest MRI, Musculoskeletal MRI, Knee MRI, Shoulder MRI, MRI Prostate, MR Urography, MR angiography of limb vessels, MR venography, Cytology & Histology Images, Diagnostic method Images, Oncology Images, Immunology Images, Forensic science Images, Clinical case Images, Ophthalmology Images, Chemotherapy Images, Transplantation images etc.

Body Image Journal mask the areas of clinical & medical sciences which include image formation, image processing, image analysis, image interpretation and understanding, computer graphics and visualization referential to diverse areas in clinical and medicinal classifications.

Body Image Journal focuses in all areas;

Clinical: Cytology & Histology, Diagnostic method, Oncology, Immunology, Forensic imaging, Clinical case, Ophthalmology, Chemotherapy, Transplantation, Rheumatology, Dermatology, Neurosurgery, Neuroendocrinology and Gastroenterology.

Medical: Radiology, Surgery, Diagnostic methods, Cloning and transgenesis, Dermatology, Neuroscience, Haematology, Dentistry, Gynaecology, Cardiology, Arthritis, Urology, Florescence Images, Endoscopy, Elastography, Tactile Imaging, Thermography, Medical Photography, Stress Imaging, Electroencephalography, Magnetoencephalography, Electrocardiography, Medical ultrasonography, Projectional Radiography, Medical Microbiology, Cytogenesis, Molecular Imaging, Nuclear Medicine and Bone Scan, Radionuclide Imaging, Optical Projection Tomography (OPT), Positron Emission Tomography - Computed tomography, CT and MR Imaging, Photoacoustic Imaging and Echocardiography.

Image Journal Submission

The mission of Clinical Image Journal is to publish, in a timely manner, high quality, impactful, innovative radiology research, clinical images, case reports, case series and clinical videos with special attention to the impact of medical imaging on patient care. The journal's publications cover all imaging modalities, radiology issues related to practice improvements, policy and education, as well as clinically-oriented imaging physics and informatics.

All submissions to Clinical Images and Case Reports Journal will be screened by the editors for scientific integrity, clinical impact, novelty, relevance, and interest to our readership. Editors may choose to send the manuscript for external double-blinded peer review or determine its disposition based on their own review.

Manuscript Submission

Authors are requested to submit their manuscript by using Online Manuscript Submission Portal:

(or) also invited to submit through the Journal E-mail Id: editor.cicrj@literaturepublishers.org

[literaturepublisher10]

Image Journal Submission

Body Image Journal: Image Journal Submission: Authors are requested to submit images in body journal, body imaging journal for publication. Body Image Journal is a scholarly open access Journal that appeals to a broad spectrum of allied professionals from clinical and medical fields up to molecular levels. It comprehensively covers new technologies, applications, issues concerning all major diagnostic methods that provide the latest information in medical and clinical diagnosis as well as machine learning for image reconstruction.

Journal Homepage: https://www.literaturepublishers.org/

Body Image Journal includes articles from various fields. Journal intends to include the topics like Magnetic Resonance Angiography, Spine MRI, General Whole Body MRI imaging, MR Arthrography, Magnetic Resonance Cholangiopancreatography (MRCP) but not limited to the below mentioned areas. Journal accepts images related to Breast MRI, Chest MRI, Musculoskeletal MRI, Knee MRI, Shoulder MRI, MRI Prostate, MR Urography, MR angiography of limb vessels, MR venography, Cytology & Histology Images, Diagnostic method Images, Oncology Images, Immunology Images, Forensic science Images, Clinical case Images, Ophthalmology Images, Chemotherapy Images, Transplantation images etc.

Body Image Journal mask the areas of clinical & medical sciences which include image formation, image processing, image analysis, image interpretation and understanding, computer graphics and visualization referential to diverse areas in clinical and medicinal classifications.

Body Image Journal focuses in all areas;

Clinical: Cytology & Histology, Diagnostic method, Oncology, Immunology, Forensic imaging, Clinical case, Ophthalmology, Chemotherapy, Transplantation, Rheumatology, Dermatology, Neurosurgery, Neuroendocrinology and Gastroenterology.

Medical: Radiology, Surgery, Diagnostic methods, Cloning and transgenesis, Dermatology, Neuroscience, Haematology, Dentistry, Gynaecology, Cardiology, Arthritis, Urology, Florescence Images, Endoscopy, Elastography, Tactile Imaging, Thermography, Medical Photography, Stress Imaging, Electroencephalography, Magnetoencephalography, Electrocardiography, Medical ultrasonography, Projectional Radiography, Medical Microbiology, Cytogenesis, Molecular Imaging, Nuclear Medicine and Bone Scan, Radionuclide Imaging, Optical Projection Tomography (OPT), Positron Emission Tomography - Computed tomography, CT and MR Imaging, Photoacoustic Imaging and Echocardiography.

Image Journal Submission

The mission of Clinical Image Journal is to publish, in a timely manner, high quality, impactful, innovative radiology research, clinical images, case reports, case series and clinical videos with special attention to the impact of medical imaging on patient care. The journal's publications cover all imaging modalities, radiology issues related to practice improvements, policy and education, as well as clinically-oriented imaging physics and informatics.

All submissions to Clinical Images and Case Reports Journal will be screened by the editors for scientific integrity, clinical impact, novelty, relevance, and interest to our readership. Editors may choose to send the manuscript for external double-blinded peer review or determine its disposition based on their own review.

[covenawhite66]

Stem cells ability to repair, replace and regenerate cells. In most animals and humans, stem cells are limited to generating only specific types of cells.

Pluripotent (aPSCs) meaning they can regenerate virtually any missing cell type, a process known as whole-body regeneration.

Many distantly-related invertebrates like sponges, hydras, planarian flatworms, acoel worms, and some sea squirts have stem cell populations that are pluripotent in adult animals. The study focuses on H. miamia, also known as the three-banded panther worm, is a species that can fully regenerate using aPSCs called “neoblasts.”

The mechanism of how (aPSCs) are produced remains unknown in any species. The focus of past scientific research was the adult organism.

The researchers knew that worm hatchlings contain aPSCs, so reasoned they must be made during embryogenesis. Ricci used transgenesis to create a line that caused embryo cells to glow in fluorescent green due to the introduction of the protein Kaede into the cell.

Is used Hofstenia miamia, a regenerative worm that possesses collectively pluripotent aPSCs called neoblasts and produces manipulable embryos. Lineage tracing and functional experiments revealed that one pair of blastomeres gives rise to cells that resemble neoblasts in distribution, behavior, and gene expression.

[verysmolspams]

TransGenesis Rhapsodos is one of my favorite things ❤️

trans genesis u r sooooo precious to me u have no idea

[fruit-worm-papers]

High-throughput library transgenesis in Caenorhabditis elegans via Transgenic Arrays Resulting in Diversity of Integrated Sequences (TARDIS)

http://dlvr.it/Srgnv7