#the serum seems to delay aging by around 40%

[logansgaar]

In light of the fact that Bucky (Loki and Thor too for that matter, since the Chrises, Tom and Seb have all aged past their characters) should pretty much still look like he did in CATFA in-universe, it's hilarious to imagine Sam slipping up one day and calling Bucky "kid" without thinking and it's mortifying for them both. Sam has a whole list of old man jokes from his time with Steve that he now gets to reuse on Bucky, except goddamnit Bucky pretty much rebuilt his personality after a factory reset from breaking conditioning so the illusion of being old breaks down easier than it did with Steve, his sense of humor is eerily close to genz/clearly influenced by Princess Shuri, and sometimes when Sam is distracted by something else, he does let "kid" drop like he does with Joaquín.

Bucky looks disturbed because Steve probably keeps accidentally calling him "son" and "kid" during their meet ups too, since there's a strong chance he has grandkids that look Bucky's age, and now Sam's doing it as well, he's in his 100s what the hell is going on? Meanwhile this is, based on a calculated estimate on the serums aging rate, what he looks like in-universe:

[orbemnews]

Novavax Reports More Delays for Its Covid-19 Vaccine Novavax, one of the first players in the race to vaccinate the world against Covid, delivered disheartening news on Monday, saying that its highly protective vaccine would not be authorized in the United States or Britain until at least July, and that it would not reach peak production until the end of the year. The delays, announced during an earnings call with investors, are the latest setback for the little-known Maryland company, which was granted up to $1.6 billion from the U.S. federal government last year and whose product has shown robust results in clinical trials. Despite these wins, the company has struggled to demonstrate that it can deliver on its promise to supply the world with 2 billion doses this year. Novavax has never brought a vaccine to market in its 34-year history. On the call, the company’s president and chief executive, Stanley C. Erck, said that the regulatory and manufacturing hurdles causing the delay have now been resolved. “Nearly all of the major challenges have been overcome, and we can clearly see the light at the end of the tunnel,” he said. Investors did not appear to agree: By Tuesday morning, the company’s stock had fallen to $133.86, down nearly 17 percent, although it rebounded somewhat later in the day. “I don’t see a lot going well for them at this point,” said Rob Smith, the managing director of Capital Alpha Partners, an investment research firm. The company’s delay is unlikely to affect wealthy countries like the United States, which is flush with vaccines from Moderna, Pfizer-BioNTech and Johnson & Johnson. But it is likely to have significant repercussions for the rest of the world, given that just last week, Novavax finalized a deal with Gavi, a public-private global vaccine partnership, to supply 1.1 billion doses of its shot to low- and middle-income countries. Novavax has struck other deals with countries like South Korea, Japan and Australia, and has set up agreements with eight production plants around the world. In January, the company estimated that it would hit its full production capacity of 150 million doses a month by the middle of this year, a prediction it later revised after facing a shortage of supplies like filters and the giant single-use bags that are used in vaccine manufacturing. On Monday, the company delayed its estimate again, saying it expected to reach production of 100 million doses a month by the end of the third quarter, and to make 150 million a month by the fourth quarter. One of its major manufacturing partners, the Serum Institute in India, has faced its own production and geopolitical challenges. A fire at the facility earlier this year reduced its capacity, and in April, Serum’s chief executive, Adar Poonawalla, called out the United States for restricting access to raw vaccine ingredients. And though Novavax’s deal with Serum is intended to supply the rest of the world through its arrangement with Gavi, the Indian government has banned exports of vaccines from the country as it struggles with a deadly second wave of Covid-19. “Serum is the backbone of vaccine supply to the world,” said Andrea Taylor, assistant director of the Duke Global Health Innovation Center, which is tracking global vaccine deals. “I think particularly for countries in South and Southeast Asia, as well as countries in Africa, it is hard to overstate the impact that this is having.” Regulatory hurdles have also set Novavax back. On Monday, company executives said that a now-resolved issue with an “assay” — a test that was needed to confirm that their product can be consistently manufactured at commercial scale across multiple production plants — was delaying regulatory approvals around the world, and that countries like Britain and the United States would not grant authorization until at least July. Company officials once said they hoped to gain authorization for their vaccine in April. The delay is particularly striking in Britain, since Novavax reported positive results of its clinical trial there in January. British officials persuaded Novavax to set up a trial there last year in part by promising speed in clinical development and regulatory approval. But time is running out: About two-thirds of British adults have received a first dose of a coronavirus vaccine, most made by AstraZeneca, and every adult is expected to be offered one by the end of July. Updated  May 11, 2021, 9:41 a.m. ET The vaccine’s role in Britain depends in part on how quickly Novavax can start distributing its shot. A British factory making the vaccines has said that it would be ready by the summer. The country has recently turned away from the AstraZeneca shot in younger people because of the risk of very rare blood clots, leaving room for Novavax to be an alternative for people under 40. The country is also studying the effects of administering a second dose of the Novavax vaccine in people who have already received a first dose from either Pfizer or AstraZeneca. In the United States, Novavax’s setback casts new light on its massive deal with the U.S. government. As recently as 2019, the company was on the verge of closing after a major trial failure for another vaccine, and it was forced to sell off its manufacturing facility to raise money. Last year, the Trump administration placed a major bet on the tiny company as part of its Operation Warp Speed project, signing a $1.6 billion contract for delivery of 110 million doses by early this year. In April, the total amount of the deal was increased to $1.75 billion, according to Novavax’s financial filings. The company’s large trial in the United States and Mexico has still not been completed, although executives said on Monday that they expected results from that study “in a few weeks.” Novavax officials said they now did not expect to deliver those doses until the end of this year or early 2022. A spokeswoman for Novavax said there was no penalty for later delivery in its contract with the U.S. government. Novavax’s spotty track record does not offer confidence that it can rise to the challenge of producing billions of doses, said Les Funtleyder, a health care portfolio manager at E Squared Capital Management who invests in domestic and emerging markets. “It seems they were really unprepared for a challenge of this magnitude,” he said. Recent news of internal turnover — such as the departure last month of Novavax’s chief financial officer, five months after taking the role, for personal reasons — does not help, Mr. Funtleyder said. “It’s a bad look,” he said. But even if it has a challenging path as a latecomer, Novavax’s vaccine could fill important gaps, some experts said. In the United States, it could be used as a booster shot to shore up waning immunity, or the Biden administration could choose to donate the vaccine to other needy countries, as it has with its unused supply of AstraZeneca doses. Novavax has said it is developing a new version of its vaccine to address the variant circulating in South Africa. And it recently announced it would begin studying the shot in children older than 12, in an effort to catch up to Moderna and Pfizer, which have already tested their products in that age group. The vaccine can also be stored at normal refrigeration temperatures, without the freezing temperatures required by Pfizer and Moderna’s vaccines. “By the end of 2021 there will still be a great need for safe and effective vaccines that can travel well,” said Ms. Taylor, of Duke University. “Novavax looks like it can fit that description.” Dr. Saad B. Omer, the director of the Yale Institute for Global Health, noted that when concerns were raised over the Johnson & Johnson and AstraZeneca vaccines because of links to blood clots, countries with multiple vaccines available were able to switch to other options. “It’s good to hedge our bets,” he said. “If we want to avoid, for example, body blow after body blow to low-income countries in many parts of the world that has an impact on everyone, we need to vaccinate a huge chunk of the world.” Benjamin Mueller and Noah Weiland contributed reporting. Source link Orbem News #Covid19 #Delays #Novavax #reports #Vaccine

[digitalyogesh]

Wrinkles on face

How To Reduce Wrinkles On The Face?

Dr. Lata Ganji

Surveyed by Expert

Dr. Lata Ganji (PhD, Pharmaceutical Science)

Composed By Minal Khona On March 12, 2020

How To Reduce Wrinkles On The Face?

Have you begun seeing abrupt changes all over since the time you hit 40? Regardless of whether you are more youthful, would you like to forestall untimely skin maturing? All things considered, wrinkles are the first and most noticeable indications of maturing. At the point when the skin gets dry, it can prompt the presence of scarce differences as you age, particularly around the eyes, mouth and between the eyebrows.

Yet, fret not! While it’s normal for your skin to foster wrinkles as you age, you can postpone their appearance and furthermore reduce the current ones with the right consideration. How about we discover how.

Features Icon Bar

Features:

What Causes Face Wrinkles?

How To Remove Wrinkles From The Face?

Will Wrinkles Be Prevented?

Where Do Wrinkles Appear?

When To See A Doctor?

What Causes Face Wrinkles?

As a feature of the maturing cycle, wrinkles are shaped where muscle development is incessant. They are additionally the consequence of the continuous reduction in filaments that give the graceful and tight surface to the skin. Here are some of significant reasons for facial wrinkles:

Maturing Skin

At the point when we age, the skin cells delayed down and the top and center layers of the skin start to begin diminishing. The dermis [1] or the center layer has a great deal of elastin and collagen filaments which give the skin its immovability. With age, this organization of strands turns out to be free and causes wrinkles.

The skin’s capacity to hold dampness, mend from wounds or burn from the sun and emit oil likewise diminishes. This adds to the presence of Wrinkles On The Face also.

Smoking

Our skin, being simply the biggest organ in the body recovers itself constantly. The old collagen separates and new collagen has its spot. One of the results of smoking, as indicated by specialists, is the diminished creation of new collagen. The absence of new collagen additionally causes wrinkles.

Facial Muscles

At the point when we giggle or scowl, or even squint, lines are framed because of the withdrawals of the muscles beneath. These incessant looks cause these lines to turn out to be more noticeable as we age.

Sun Damage

One of the primary driver of wrinkles is openness to the sun’s UV beams, which can even prompt untimely maturing. The UV beams separate the collagen strands and lead to the creation of a protein called metalloproteinase [2], which changes the collagen.

During the cycle, in any case, some solid collagen fiber gets harmed, bringing about the scattered development of strands. So when this muddled reconstructing measure happens over and again because of openness to the sun, wrinkles are shaped.

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How To Remove Wrinkles From The Face?

Wrinkles On The Face

Careful and Non-Surgical Options

There are a few careful and non-careful alternatives accessible in the market today for the individuals who need to limit the presence of the wrinkles all over. We drill down the absolute most famous ones:

A. Dermabrasion

Dermabrasion [3], is otherwise called careful skin planing. It is a method performed for the most part by a plastic or dermatologic specialist. Here, a particular instrument is utilized to ‘sand’ the skin – an activity that eliminates the top layer of the skin, which gives the face a smoother appearance with less noticeable wrinkles.

B. Laser Therapy

A laser facial treatment to eradicate minor flaws like sun spots, lessen the presence of open pores and eliminate epidermal bluntness is very mainstream. The method includes the development of a laser wand everywhere all over to light up your skin for a more youthful appearance.

C. Botox

The infusion of Botulinum Toxin (botox) is as yet the most well known among non-careful medicines. Botox is infused into the skin, which loosens up the facial muscles and lessens the wrinkles and lines, making you look more youthful.

D. Substance Peels

This strategy includes the evacuation of old skin with the assistance of a substance strip. New skin layers fill in the spot of the old skin giving you more youthful looking skin. These are viable to lessen profound lines and wrinkles, skin break out scars and broad sun harm.

E. Facelift

This is a surgery where the restorative specialist lifts and pulls back facial skin to make it more tight and to dispose of hanging.

F. Fillers

Injectable fillers to give you more tight and more youthful looking skin are a decent alternative for the individuals who would prefer not to have plastic medical procedure.

G. Fluid Face Lift

This is a non-surgery where injectable gels are utilized as fillers to decrease wrinkles and give an inconspicuous cosmetic touch up, along these lines giving you a smoother and more youthful look. Its belongings can keep going for as long as two years.

Over-The-Counter (OTC) Anti-Wrinkle Creams

There are a few enemy of wrinkle creams accessible on the lookout. Most great ones will incorporate fixings like CoQ10, peptides, green tea separates, nutrients An and C, and alpha hydroxy acids. Some even utilize fundamental oils and SPF.

Effective Vitamin C And Vitamin A Retinoids

Nutrient C [4], with its high substance of cell reinforcements, and retinoids [5], which are subordinates of Vitamin A, are generally found in most enemy of maturing creams.

It has been demonstrated that customary use of a cream containing retinol and nutrient C lessens the presence of almost negligible differences and wrinkles as retinoids increment the creation of collagen. Retinoids decrease almost negligible differences and wrinkles by expanding the creation of collagen.

Home Remedies

Anticipation is the most ideal approach to keep wrinkles under control. In the event that you start a skincare routine when you are in your 20s, you can see the outcomes even after thirty years. Normal fixings and some fundamental oils are the most ideal approach to look youthful:

A. Back rub

At home, you can knead your face with a cream or a fundamental oil to animate the blood stream to the face. Continuously knead a vertical way, particularly for the neck and the region over the facial structure. Back rub the cheeks and temple in delicate, round movements.

B. Fundamental Oils

Fundamental oils that are known to help lessen the presence of wrinkles with customary use incorporate pomegranate, lemon, ylang-ylang, rosemary, sandalwood and lavender oils. Additional virgin coconut oil is likewise a generally excellent alternative to decrease wrinkles.

C. Egg Whites

Egg whites contain proteins that can help fix the skin and have saturating properties that can forestall scarce differences on dry skin. It additionally assists with shutting open pores and diminish the size of the enormous ones. You can apply it straightforwardly on the face or make a cover with different fixings.

D. Aloe Vera

Known for its advantages since days of yore, aloe vera remove helps in the expanded creation of collagen in the skin. This thusly assists with decreasing the noticeable indications of maturing as it improves the skin’s flexibility. Aloe vera additionally contains fundamental amino acids and nutrients B and C, which can assist with battling free revolutionaries that rush the maturing cycle.

E. Banana Mask

Bananas are a known wellspring of nutrients A, B and E just as potassium. The cell reinforcements present in bananas can postpone the indications of maturing. Pound a banana and blend in with a spoon of nectar which is a characteristic cream. Apply everywhere on the face and neck and leave on for 20 minutes.

F. Quality Foods

In the event that you eat food varieties that are known to postpone maturing, the impacts will show on your skin. Organic products like papaya, blueberries, and pomegranates; vegetables like spinach, red ringer pepper, broccoli and avocado likewise forestall the presence of wrinkles. Dry organic products, particularly almonds have nutrient E that postpone maturing.

G. Facial Exercises

There are a few facial activities you can do to address the wrinkles in explicit spaces of the face. From activities to lessening crow’s feet and grimace lines to smoothening the temple and lifting the neck, you can do these activities yourself to decrease wrinkles and scarcely discernible differences.

Could Wrinkles Be Prevented?

To forestall the presence of scarcely discernible differences and wrinkles, you should abstain from smoking, liquor, late evenings and remaining out in the sun without sufficient security. Eating the right food and staying away from greasy and singed food likewise helps in keeping the skin imperfection free.

Where Do Wrinkles Appear?

Wrinkles can show up everywhere on the face, however they are most apparent when they show up around the eyes, neck, cheeks and temple. They generally seem where the development of the facial muscles is generally regular. This is the way they show up:

Wrinkles On Forehead

These generally show up as even lines across the brow or as upward grimace lines between the eyebrows. The level lines are an aftereffect of oftentimes lifting your eyebrows. At the point when you glare, the eyebrows pack together and the lines framed at the same time become wrinkles as you age.

Wrinkles On Neck

The neck is a fragile region and with age, the skin begins to dry and wrinkles are shaped. These are generally level. They become more noticeable as we age, in light of the fact that the skin of the neck begins to list, making the lines look like notches.

Wrinkles On Eyes

These will in general show up first. Regardless of whether you squint your eyes in the sun, or while you smoke, lines known as crow’s feet show up on the sides of the eyes. The region beneath the eyes is likewise inclined to wrinkling as the skin there is extremely flimsy and fragile. One approach to forestall them is to abstain from scouring the eyes every now and again; and utilizing an under-eye cream.

Wrinkles On Lips

Lines around the lips are normally the last to show up. Nonetheless, in the event that you smoke, the puckering movement while sucking on the cigarette can cause fine vertical lines along the upper lip.

Wrinkles On The Face , lips and eyes

When To See A Doctor?

You can counsel a dermatologist in the event that you wish to decide on careful or non-careful treatment to

[ligadosnatelinha]

Start Eating These Foods The Moment You Feel Like You May Be Losing Your Hearing

start eating these foods the moment you feel like you may be losing your hearing - Homemade medicine

start eating these foods the moment you feel like you may be losing your hearing

Actually, some imbalances in the nutrition may be the main cause for the decreasing of your hearing sense. The loss of hearing related to the aging process is not caused because of some mechanical dysfunction inside your ear. In fact this is how our brain is processing the information it receives, which results in decreased hearing.

In fact, the brain has the ability to support your hearing and give feedback to the ears, it filters the information only that is important and what you want to hear, but once you go over 40 or 50 this ability is lost. Without the filtering of the brain, it would just be too much information that you won’t be able to accumulate, and you will end finding difficulties to sort them.

But don’t panic, because there is a way to reverse the process of age-related hearing loss.The Tinnitus which is mostly causes damage to the ear from noises, can be improved as well, and a sudden loss of hearing can be improved as well.

Nutrients that Improve and Protect Hearing

In the group of nutrients who provide the most benefits to improve and protect your hearing are the following ones:

Magnesium

Zinc

Folate

Crotenoids, mostly vitamin A and astaxanthin

The listed nutrients are supporting hearing in many ways, such as:

Prevent from free radical damage.

Protect from oxidative stress in the cochela

Improve homocysteine metabolism

Reduce the cochelar damage that is related to the compromised vascular system, due to the improvement of the blood flow

There is a mixed support for vitamin A. There was a study in which were included about 65,500 women, and there was no connection found between the risk of hearing loss and the intake of vitamin A. But many studies have proven this study very wrong, by finding a correlation between these two. Weston A. Price, reported:

“A study from 1984 which was done in Europe, has reported 5-15 decibel improvement in those patients who had reduced hearing due to aging, only by the consumption of vitamin A and vitamin E. While some other studies have concluded that decreased vitamin A levels resulted in declining many sensor cells in the tongue, inner ear and nose.”

“A study done in 1993, concluded that vitamin A is the only one that has the ability to trigger the regeneration of the cells called, mammalian auditory hair cells. While in 2009, a Japanese study has shown that adults who were maintaining the vitamin A levels around the normal, as well as carotenoids had lower risk of hearing loss.”

“According to a 2014 study, a group of researchers have found that if a person is in lack of vitamin A during pregnancy, mostly in the early stages, may cause a sensorial hearing loss and offspring to the inner ear malformations.”

Tinnitus can be Improved by Folate

For tinnitus which is induced by noise, which is mostly followed by chronic ear ringing, the B9 vitamin or also known as folate, was proven to be very helpful. Homocysteine can be also lowered by folate, and the age-related hearing loss is mostly caused by having a high blood levels of homocysteine.

Therefore, you can raise the levels of folate in your body by eating a lot of raw, organic and fresh leafy green veggies. And the folic acid is actually the synthetic form that is added into many supplements.

You consume more folate from these foods than to take any folic acid supplements. The folate must be active in its biological active form, known as -- L-5-MTHF. This form is able to go through the blood barrier of the brain, straight into it.

Many studies have also proven that adults are not able to transfer the folate in this active form, because they have reduced activity of the enzymes, which is triggered genetically. Therefore, if you are willing to take any vitamin B supplements, make sure that they contain natural folate, not the synthetic folic acid. But children convert the folic acid much easier than natural folate.

Broccoli, turnip greens, spinach and asparagus, all of these are one of the richest sources of folate, and some beans as well, like garbanzo beans and lentils.

Zinc for Sudden Hearing Loss

According to some researches, sudden hearing loss can be improved that by the increased intake of zinc. The sudden hearing loss is called SSNHL, and it can be treated with certain steroids consumed in big doses, even though that the consumption of steroids is controversial, and there is some evidence that say the efficacy of them is very limited.

But there is good news as well, 47-63% of the patients who are affected, in the end have recovered the hearing most of it or all of it. But the cause of the sudden hearing loss still remains unknown, and there is a simple theory that says it is mostly caused from immunologic diseases or a viral infection. This may explain why the zinc is that much beneficial for the treatment of this issue and the high rate of the recovery process.

The zinc contains strong anti-viral properties, and many researches have proven that the zinc has the ability to prevent from particularly common colds and viruses by attaching or replacing to your nasal membranes. The zinc has the ability to boost your immune system as well, which gives your body the ability to have more protection against many viral infections.

In a study which was done, 66 patients who had SSNHL were divided in two smaller groups randomly one half received oral zinc gluconate and corticosteroid treatment, while the other group recieved corticosteoit treatment only.The levels of zinc were ascertained at the end of the study.

The group which received the zinc serum had much bigger percentage of recovery and improvement in the hearing. The authors reported:

“By some correlation analysis, there were some relations found between posttreatment hearing thresholds and serum zinc level changes, and between the percentage of recovery in the zinc group with the changes of serum zinc levels as well.”

” The intake of zinc supplements enhances the recovery process of hearing, in patients who are dealing with SSNHL. The zinc’s anti-inflammatory and antioxidant properties, help to reduce the oxidative stress of the cochela in patients who deal with SSNHL, and with this, we know another new way to treat this disease.”

The Richest Source of Zinc is a Well-Balanced Diet

You can create an imbalance by consuming a single mineral independently while the consumption of all others is normal or reduced. An imbalance is very likely to be caused by the consumption of zinc supplements, therefore the intake of zinc independently may be a little bit problematic. The increased intake of zinc has been proven to:

Induce stomach pain, diarrhea, vomiting and nausea.

Elevates the risk of prostate cancer in men.

Correlates with the ability of your body to absorb minerals, such as copper, and this may cause the development of anemia.

The recommended daily allowance or RDA of zinc is known to be:

3 mg for infants

5 mg for children that are between 4 and 8 years old

8 mg for children that are between 9 and 13 years old

8 mg as well or women (3 mg or more, during pregnancy or if you are lactating)

11 mg for adult ment

It is considered to be excessive anything that is more than 50 milligrams. To prevent form the excess intake of zinc, try to consume it through foods, that way you are safe. Besides that, foods that are rich in proteins such as seafood and grass-fed beef, there are some dietary sources that are rich with zinc, like tahini or ground sesame seeds, almonds, cashews, sea vegetables, spinach, cheddar cheese, crimini mushrooms and pumpkin seeds.

There is between 16 and 182 milligrams of zinc in 100 grams serving of Ouzters, which is on top of the list of foods that are rich in zinc, which is followed bu the liver that contains 12 milligrams of zinc in 100 grams serving. This seems that zinc is much easier absorbed from animal sources than any other plant source. Therefore if you are looking for a way to quickly increase the zinc levels in your body, you need to increase the consumption of liver and organic grass-fed beef!

Intravenous Magnesium May Also Improve

Sudden Hearing Loss

Also it was proven that SSNHL can be improve by the increased intake of magnesium. In a certain study, 48% of the patients who were dealing with SSNHL, recovered after they received a mixture from carbogen inhalation (a mix of oxygen gas and carbon dioxide) and intravenous magnesium. And 27% more have experienced this miraculous improvement.

There were a few factors that were reducing the effect of this treatment, like delaying the treatment for more than 8 days, and vestibular symptoms (the patients that had vertigo).

Increasing NT3 Production Restored Hearing in Mice

Some researchers came to a very interesting finding a few years ago, when they were looking for ways to restore the hearing which was lost due to noise. The hearing loss process could be reversed only by the increased production of a protein known as neurotrophin-3 (NT3), but the experiment were done on mice which lost their hearing due to very loud noises.

Therefore, it was concluded that the NT3 protein was playing a huge role in the bond between the brain and the ears. This protein has the ability yo establish a link or a bond between the nerve cells in your brain with the hair cells in your inner ear. They are called ribbon synapses, and these can be damaged due to very loud noises, and can result in hearing loss as well.

The ribbon synapses are very likely to be damaged in the aging process, therefore we are finding out that the production of the NT3 is reduced as we age. In order to boost its production, the scientists were using conditional gene re-combination. The Medical News Today reported:

“The researchers have the ability to activate genes in the particular cells only with a drug that stimulates the cells to read the additional copies of a gene that was put inside of them. This study was using the same technique to activate the NT3 genes, wgich were introduced to the cells that were supportive, which were located in the ears of the mice, which lost their ability to hear due to very loud noises.”

“In the inner ear the supporting cells were introduced to the drug tamoxifen, which stimulated them to increase the production of the NT3 protein. The researchers concluded that the production of NT3 in the mice was elevated, and the mice recovered their hearing ability in only two weeks, compared to those mice that didn’t have increased production of NT3.”

“They are now looking for a way to create a drug or a cure that will provide the same effects, that will increase or boost the production of that protein, in order to help many people who have lost their hearing ability. The researchers are sure that this method will work on humans too, but it would be a lot more simple to develop a drug which will be consumed as much as someone needs to consume it, in order to restore the hearing ability.”

NT3 Expression is elevated by Astaxanthin

According to a Chinese study, astaxanthin can be used for the same purpose, as the drug which scientists want to develop for the increased production of NT3. Astaxanthin is a member of the carotenoid family, and it is said that it is one of the most potential antioxidants that was given to us by Mother Nature.

The astaxanthin has far more potential than alpha-tocopherol, beta-carotene and lutein. It makes very powerful free radical scavenging activity that is protecting the organs, body tissues and cells from the oxidative damage. Also it has one of the strongest anti-inflammatory properties, and that gives it the ability to go through the blood-retinal barrier and the blood-brain barrier.

The astaxanthin has been proven ti be very beneficial for your eye and brain health, and because of its ability to increase the NT3 production, it is highly beneficial for your hearing too. There was a study which was done on rats, who have injured the compressive spinal cord, in the study was watched the effect of astaxanthin on the expression of NT3, and it was proven that this protein was able to boos the growing process of the spinal cord neurons too. The authors also said that the astaxanthin is promoting the expression of NT3 as well.

Astaxanthin can be taken naturally only from a few sources, two in fact -- the creatures in the sea that consume algae, like shellfish, krill and salmon and the microalgae that are producing it, which are known as Haematococcus pluvialis. If you are trying astaxanthin for the first time, we highly recommend you to take a dose of not more than 2 mg a day.

If you are consuming astaxanthin through krill, be very aware that every krill product contains different levels of astaxanthin, therefore you might want to check the label in the back. Even that it is still unknown which dose is the best to be taken in order to improve your hearing, the intake of 8-10 mg of it on daily basis is for improving your eye health.

You can Improve Your Hearing by Boosting BDNF as Well

A study which was done in 1996, researchers concluded that you can prevent from the the loss of auditory neurons and auditory hair cells by any therapy that increases the BDNF or NT3. Therefore, it was concluded in earlier studies that the BDNF plays one of the main roles in the survival and development of the auditory neurons in our brain, the BDNF stands for brain-derived neurotropic factor.

It is interesting that the only natural factor that can increase the BDNF is exercising. This is why exercising is so important to prevent cognitive decline, because a part of it is related to the boost of BDNF. There is the reason why exercising is so beneficial if you want to prevent from hearing loss.

What is the Best Way to Protect Your Hearing?

At the moment 360 million people worldwide, are dealing with hearing difficulties and hearing loss, and the causes are all different, some due to infection some due to very loud noises, some due to the aging process. And statistically 50% of these cases may be avoided. Also the cases that are noise-induced hearing loss and hidden hearing loss are included! Prevention 101 from hearing loss, is protecting yourself from very loud noises. There are a lot more ways to prevent from hearing loss, here are a few of them that you can do:

Lower the volume on the personal audio devices.

Wear earplugs when you are passing though very noisy and loud venues, and you should wear protection if you are working in a louder environment as well.

Download a decibel meter on your phone, which will show you a warning sign when the volume is increased to a level when it can cause damage.

When you are using personal audio devices take breaks by listening regularly.

Have a limit of how much time you spend in a noisy environment or you do noisy activities.

Use headphones or earphones that will fit perfectly into your ear, that way you will listen clearly at lower volume as well.

Reduce the use of personal audio devices in a day to an hour.

Think about moving into another place if you live in a very noisy neighborhood.

In order to protect your ears from street sounds, lawnmowers and traffic use some sound-blocking headphones.

Also when you are mowing the lawn, use protection to prevent from the condition.

If you are unable to move from a noisy neighborhood, try to add some acoustical tile to your walls and ceiling to lower the noise that comes from the outside.

Heavy curtains, rugs, insulation and double-paneled windows may help as well

But besides these things, maintaining a healthy diet that is rich with healthy foods is the best way to protect yourself from hearing loss, that is related to aging. Even if you have already lost some hearing degree, you might be able to get it back by maintaining a balance of the intake of carotenoids, mostly vitamin A, magnesium, zinc, folate and astaxanthin!

Similar content: start eating these foods the moment you feel like you may be losing your hearing: IT’S THE MOST EXPENSIVE FRUIT THAT EXISTS REMOVES ANEMIA IN 2 DAYS AND REGULATES DIABETES STOP BUYING AVOCADOS: HERE’S HOW YOU CAN GROW AN AVOCADO TREE IN A SMALL POT AT HOME WHAT IS THE BEST OIL FOR DEEP FAT FRYING? 14 POPULAR OILS ANALYZED

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Best Two Skin-care TIPS TO SLOW DOWN SKIN AGING

Aging happens to be an inevitable physiological process for mankind. You are bound to get older over the years. Even though inevitable, nevertheless, it does not mean that there is no way for you to slow it down or make it less apparent. In case you're looking for beneficial advice on how you can make aging process slower, the following are 2 things you should do. 1. Stay clear of sleeping with your face pressed against your pillow case Relaxation is among the most essential things to delaying signs and symptoms of skin aging and having far healthier skin. You need to have around 6 to 8 hours of proper rest in the evening to assist the skin repair and replenish itself. In addition to the having a good amount of sleep, the sleeping position is necessary to how your skin looks, too. Regularly sleeping with your face against the pillow can put you at an increased risk of forming “sleep lines”. After a while, these lines could turn into fine lines and wrinkles. Sleeping in such way is also one good reason why you normally seem to awaken looking fluffy and bloated. The position allows for blood and fluid to pool in your face. In addition to facial lines, pressing the face against your cushion overnight can as well lead to skin breakouts, especially if you are not always changing your bed sheets or linens. Having troublesome garments is bad for the skin, too. Frequent replacements and sleeping in a supine position will save you from having to constantly use the cover-up for pimples prone skin in order to hide out your skin’s imperfections. 2. Bring an anti-aging solution to your skincare plan Moisturizers are great in maintaining your skin’s moisture and water level. Yet, for aging skin, they may not be adequate. Anti-aging serums carry powerful materials to cope with your skin’s special needs, like anti-oxidants to secure your skin against toxin damages. A number of these serums can also supercharge collagen creation so that your skin can get back its elasticity and pliability. Serums might be best used way before you'll see signs and symptoms of skin aging.You don’t need to wait until you are 40 before you begin using serums. The truth is, the sooner start, the slower fine lines and wrinkles will show up on your face.

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obviously this isn't something visible without CGI since the actors don't actually age at the same rate as their characters, so we have to use Vampire Logic and the suspension of disbelief when it comes to the super soldiers (and Asgardians for that matter). The characters don't look the same age as their actors anymore, their actors have matured but they're still more or less the same as when we first met them.

I wonder if in-universe that characters who don't have delayed aging ever look at Steve, Bucky, Thor or even Loki and think what the fuck you're a baby

Sam is the best guy to illustrate this point.

Sam was 34 during CATWS, and Steve and Bucky were both around 27-28 physically (accounting for the delayed aging of the serum negating any time Bucky spent out of ice, which I've seen most people estimate as being no more than 2 years in total over the entire 50+ year span, and Bucky was 26 when he got his serum in Oct 1943.)

By the time Endgame rolls around, Steve is meant to be 38 but if I've got the math right with some estimation on how old he looks as Old Man Steve vs how old he actually was by then, it's ~40% slower than baseline humans. So in-universe he only aged about 6 years in the 10 years between meeting Sam and Sam dusting back into existence. Meaning before he dipped and came back as Old Man Steve, Steve looked about 33-34.

As of TFATWS, Sam is still 38, which means by the MCU's present day, which is 2026, Sam is 40-41.

Bucky on the other hand (and please remember I mean Bucky the character here, not Sebastian since that's literally impossible) who by the way was not aging at all for 5 and a half years (the Blip and the 6 month freeze in Wakanda) aged about ~2.5 years the entire time between CATWS and TFATWS, so he only looked about 30 during the show. Even by 2026, he's only looking about 32 at absolute max.

In-Universe, Sam has witnessed two of his friends barely age a DAY in a decade. Like how is that not a massive mind fuck. There must come a day where it just hits Sam all at once that Bucky looks really fucking young, he's in his 40s now, even with the Blip, but Bucky still hasn't physically reached the age Sam was when they met 12 years ago in DC.

Don't even get me started on how Thor must look to Bruce, Tony, Natasha, Jane, Darcy and Clint, since Thor in-universe still only looks 27 aka the age Chris H. was when he was filming Thor in 2011. Super soldiers age slower but Asgardians practically come to a stand still once they hit maturity.

Edit: also to add to this, I'm not sure but it doesn't look as if the serum Isaiah, John Walker and Alexei have slows their aging down at all. It seems to be just something Steve and Bucky's has? (We also know Bucky has a different serum, so his aging might not be the same as Steve's was, in the comics at least I think the Infinity Serum stops his aging completely but don't quote me on that.)