#stem cell therapy for fertility

[jcsmicasereports]

Hydroxyurea and Sperm Abnormalities in Patients with Sickle Cell Disease by Dr. Salma M. AlDallal in Journal of Clinical Case Reports Medical Images and Health Sciences 

ABSTRACT

Hydroxyurea is a key treatment option for patients having sickle cell disease. Although the treatment has been effective in improving the survival rate, new concerns over improving quality of life are forthcoming due to spermatogenesis-related toxicities and teratogenic effects. The available evidence shows that hydroxyurea might exacerbate the existing sperm abnormalities. There is a lack of comprehensive, systemic evidence to demonstrate the precise effects and role of hydroxyurea on sperm abnormalities in patients with sickle cell disease. Patients and healthcare providers require accurate and extensive information on sperm-related toxicities to make informed decisions. Here, I discuss the effects of hydroxyurea (HU) on sperm parameters, clinical study evidence, and treatment options available for fertility preservation in these patients.

Keywords: Sickle cell disease, Hydroxyurea, Sperm abnormalities

INTRODUCTION

Sickle cell disease (SCD) is a group of genetic blood disorders that leads to abnormality in hemoglobin. In patients with SCD, newer medical treatments have improved survival rates and quality of life along with a reduced disease-related morbidity. Consequently, the focus of the treatment is diverging to encompass the reproductive issues associated with these treatments. In adolescents and young patients with SCD, sexual maturation is delayed by 1.5-2 years [1, 2], and approximately 24% of SCD patients may have hypogonadism, infertility, erectile dysfunction, and poor libido [3]. The issues related to fertility and reproductive organs in SCD are either related to disease or to the treatments used to treat SCD-related morbidity.

Reduced SCD-related morbidity has been observed with treatments like hydroxyurea (HU) and hematopoietic stem cell transplantation (HSCT). However, adverse effects and toxicities associated with these therapies are a concern. HU use has been associated with sperm abnormalities and teratogenic effects [4, 5]. However, HU affects rapidly dividing cells, raising concerns about related toxicities. Therefore, it is essential to evaluate if there is an exacerbation of fertility problems in men with SCD. This review summarizes the spermatogenic effects of HU in males with SCD.

Fertility issues in males with SCD

Some of the disease-related fertility issues observed in patients with SCD are hypogonadism, sperm abnormalities, erectile dysfunction, delay in sexual maturation, and abnormal hormone (testosterone, follicle-stimulating hormone (FSH), and luteinizing hormone (LH)) levels.

The sperm abnormality rate is as high as 91% in males with SCD [6]. Although some reports attribute sperm abnormalities to delayed puberty in males with SCD [7], some others attribute it to testicular infarction or hypogonadism. It is also worth noting that sperm abnormalities also exist with normal testosterone, FSH, and LH levels [8].

In addition to sperm abnormalities, the incidence of erectile dysfunction in men with SCD is reported to be 21%–35% [9-11]. Also, a decrease in semen is reported in men with SCD [12]. Laboratory findings show low testosterone levels with variable FSH and LH levels. Moreover, abnormalities in accessory organs like seminal vesicles and prostate glands may be present due to recurrent urinary tract infections. These reproductive issues are exacerbated by therapies like HU, which have therapeutic effects through impairing DNA synthesis.

HU in treatment of SCD

HU is approved for the prevention of vaso-occlusive pain in SCD. HU is a ribonucleotide reductase inhibitor that impairs DNA synthesis due to its S-phase-specific cytotoxic action. It is an antimitotic agent that can impair human spermatogenesis. It is a disease-modifying therapy that decreases episodes of acute pain and acute chest syndrome in SCD patients [13]. The HU therapy increases the fetal haemoglobin, which does not sickle under low oxygen tension. Low-dose HU therapy (10 mg/kg/day) has been effective in improving clinical and hematological parameters, reducing painful crises, and reducing blood transfusion requirements in SCD patients. Although HU has improved the quality of life and survival rate, its use is limited by its toxicities, particularly its effect on fertility parameters.

SCD itself manifests in some abnormalities like spermatogenesis, and seminal fluid, which may be exacerbated with cytotoxic HU therapy. HU is associated with abnormal sperm morphology [14] and a decrease in sperm count [14-16] in patients with SCD. At a therapeutic dose, it has short-lived, irregular cytotoxic effects on dividing cells [4]. Since it is an antimetabolite, it is hypothesized to have a risk of affecting sperm development [4]. These effects are often brief and reversible with discontinuation of the drug administration.

Infertility in Men with SCD

Although HU treatment has improved outcomes in patients with SCD, it has been associated with effects on spermatogenesis and teratogenicity, for example, testicular atrophy, hypogonadism, decreased sperm count, abnormal sperm motility, and abnormal sperm morphology.

Hypogonadism

Male hypogonadism is decreased functional activity of the gonads that results in a testosterone deficiency. Testosterone deficiency can cause infertility, muscle wasting, and the absence of secondary sex characteristics. The mechanism for the cause of hypogonadism may be primary gonadal failure [17-19], repeated testicular infarction [20], zinc deficiency [21, 22], and partial hypothalamic hypogonadism [23].

Abnormal spermatogenesis

Impaired spermatogenesis has been reported in male patients with SCD receiving HU therapy, which leads to testicular atrophy, oligozoospermia (low sperm count), abnormal sperm morphology, and azoospermia (decreased sperm motility) [6, 15, 16, 24-31]. It is yet unclear if the abnormalities directly affect HU therapy. However, some researchers believe that the extent of sperm abnormalities might be associated with the length of HU therapy [29, 30]. Since SCD is a genetic condition manifesting at an early age, the duration of HU therapy remains long.

Abnormal Hormone level

A few studies have reported altered levels of testosterone and dihydrotestosterone, FSH, and LH in patients with SCD [12, 32, 33]. The testosterone levels have a direct effect on fertility [6], reduction in semen volume, sperm count, and motility in sickle cell male patients [10].

Priapism

Priapism is defined as a prolonged and lasting continued penile erection unrelated to sexual interest or stimulation [34]. The prevalence of priapism and erectile dysfunction in patients with SCD is 45% and 30%, respectively [35-37].

Penile erection is regulated by the neurotransmitter nitric oxide (NO). In SCD patients, the bioavailability of NO is decreased, disturbing the relaxation of penile smooth muscle [38, 39]. Also, the adenosine regulation pathway might be contributing to the pathophysiology of priapism in SCD patients.

Studies evaluating the effect of HU therapy on spermatogenesis SCD patients

Several studies have reported the role of HU in the exacerbation of various sperm abnormalities in patients with SCD. A non-interventional study (ESCORT-HU-European Sickle Cell Disease Cohort-Hydroxyurea) evaluated safety, morbidity, and mortality in 422 SCD patients of age 15years and older treated with HU [40, 41]. The study reported 67 pre-treatment and 24 during treatment semen analyses. Before treatment with HU, 49% of sperm analyses were normal, and 25% were abnormal (at least 1 abnormality: sperm mobility, sperm count, appearance). The rate of abnormalities during HU treatment increased to 50%. The abnormalities observed were asthenospermia, hypospermia, oligospermia, azoospermia, and atypical forms. These results confirmed that sperm abnormalities are exacerbated after HU treatment.

A prospective, Phase 4 multicentre study called HYDREP (NCT01609192) assessed the effect of HU treatment in patients with SCD [42]. The study reported a significant and rapid decrease in mean total sperm count from 129.8 million at baseline to 24.1 million at month 6. Furthermore, 86% of patients had an abnormal value of total sperm count at month 6 compared to only 40% at baseline. Researchers also found that 6 months of HU treatment did not affect the semen volume. They reported that the treatment of SCD with HU causes significant abnormality in spermatogenesis. After treatment, the number of men with abnormal total sperm count and cryptozoospermia increased to 30 patients and 5 patients, respectively. Additionally, six patients (17%) became azoospermic, and 19 were oligozoospermic.

An unmatched case-control study in Nigeria compared serum testosterone concentration among 47 patients with hemoglobin phenotype SS and 28 volunteers with hemoglobin phenotype AA [43]. The concentrations of serum testosterone in 44 of 47 hemoglobin phenotype SS patients were significantly lower as compared to 7 of 28 volunteers with hemoglobin phenotype AA.

A group of researchers evaluated the effect of long-term HU treatment from childhood to adult age in four patients [44]. These patients were receiving HU treatment for more than 8 years. They observed that two patients experienced severe oligozoospermia and two azoospermia. The treatment exposure in patients experiencing oligozoospermia was shorter (8 and 9 years) compared to patients experiencing azoospermia (12 and 15 years). There was also an increased percentage of abnormal spermatozoa morphology in these patients.

Furthermore, a study assessed spermatogonial quantity in prepubertal patients who received alkylating agents to compare with patients who received non-alkylating agents. They demonstrated that the quantity of spermatogonia per transverse tubular cross-section was significantly low in patients with SCD receiving hydroxyurea (0.3 ± 0.6, n = 6; P = 0.008) [45].Contrarily, a recent study reported no difference in semen volume, sperm concentration, total sperm count, or spermatozoa motility, morphology, and vitality between patients with SCD who received HU before puberty and who did not receive HU during puberty [46].

Semen analysis

A significant reduction in sperm density, ejaculate volume, sperm motility was reported in the SCD patients compared to the control subjects [43]. Likewise, some former studies that performed semen analysis in men with SCA reported a reduction in sperm motility, sperm density, and sperm morphology [44]. Similarly, Osegbe et al. and Agbaraji et al. analyzed sperm density, motility, morphology, and semen volume in patients with SCD. They reported a decrease in sperm motility, sperm density, and abnormal morphology in patients with SCD. [12, 47] Osegbe et al. observed no difference in semen volume [33]. Additionally, Friedman et al. reported oligospermia in 3 out of 4 patients with SCD [47].

Similar to Osegbe et al., a recent study also reported a normal volume of ejaculate in 75% of the samples of SCD patients. However, all sperm parameters during HU treatment were affected [47]. There were no incidents of azoospermia in five patients, although a marked decrease in sperm density during the HU treatment compared to before the HU treatment was reported. Interrupting HU treatment did not help recuperate the sperm parameters to initial levels.

However, before HU was established as a standard of care to treat SCD, subfertile range sperm parameters had been reported in patients. More recent studies have reported at least one abnormal sperm parameter in about 90% of patients [47].

HU treatment, even in low doses, exacerbates sperm parameters abnormalities in SCD patients. Therefore, routine seminal fluid parameters assessment is recommended to monitor sperm parameter changes during treatment with HU.

Treatments Available

For patients who have abnormal spermatogenesis due to their underlying condition or treatment of the conditions, the option of fertility preservation can be considered. The “optimal” age for fertility preservation is still a discussion. Below are some of the options available [46]-

Erectile dysfunction can be managed with penile implants effectively

Testicular tissue cryopreservation

Gonadal shielding

Sperm cryopreservation

Testicular sperm extraction

Electroejaculation- electrical current to trigger ejaculation.

Symptoms of hypogonadism can be treated with testosterone undecanoate injections12 and clomiphene13

In prepubertal males, patients have very limited experimental options, for example, removal and preservation of part of the testicle [47]. However, there have been no reports of live human births from re-implanted testicular tissue yet.

Counseling about infertility risk associated with the disease and treatments, and options for fertility preservation is important in these situations. Many unresolved ethical dilemmas arise for pediatric patients regarding counseling about fertility issues and preservation. The first dilemma is with whom the responsibility of making the decision should rest. Although some guidelines consider it should be parents, often patients (mostly children in case of SCD) and parents may have different opinions and choices. The American Academy of Pediatrics has published guidelines encouraging healthcare providers to discuss the issues and options with patients and guardians [48].

Since fertility preservation may not be feasible in all cases of SCD, regular monitoring for sperm abnormalities during HU therapy has been suggested.

Conclusions

HU has significantly improved the treatment outcomes in SCD patients. However, some concerns regarding the cytotoxic effects of HU on spermatogenesis emerge. Extensive research is required to evaluate the before and after treatment sperm parameters and the effects of treatment with HU on spermatogenesis.

Newer medical advances have improved survival rates and reduced disease-related morbidity in SCD patients, bringing reproductive issues to the forefront. Prospective, large population-based studies among patients with SCD are required to determine cellular and functional impairment of fertility and evaluate the impact of HU therapy on the impairment.

The clinical practice and future research should be streamlined to focus on improving the quality of life along with the prognosis of the patients. The patient-centric research will help in better management and treatment of patients with SCD with HU therapy.

[sarajcsmicasereports]

Case Report- A challenging case of severe Asherman’s syndrome in Reproductive MedicineFollowed by twin delivery by Lamiya Mohiyiddeen in Journal of Clinical Case Reports MedicaI Images and Health Sciences 

INTRODUCTION

This is a case report of a severe case of Asherman’s Syndrome who underwent multiple hysteroscopic procedures and embryo transfers over a span of 10 years. Her last embryo transfer was successful after the 5th hysteroscopy and high dose estrogen treatment. She delivered preterm twin babies.

CASE REPORT

Mrs. A was first seen with infertility and secondary amenorrhea. She was nulliparous with history of two surgical evacuations.

Her pelvic scan showed very thin endometrium of 2.5mm. She had hysteroscopy done 3 times to manage intrauterine adhesions in other centers.

When she then attended to start IVF treatment at St. Mary’s her FSH/LH level was very high and she was diagnosed premature ovarian failure. She underwent In Vitro Fertilization (IVF) cycle with donor eggs and partner’s sperm, had hormone replacement therapy (HRT) & fresh embryo transfer with single blastocyst but this was unsuccessful. Three blastocysts were frozen in that cycle.

First frozen embryo transfer with single embryo was unsuccessful. Prior to next embryo transfer scan showed fluid in endometrium. Diagnostic hysteroscopy diagnosed recurrence of Asherman’s Syndrome. Following this yet another operative hysteroscopy at our centre was done using versa point mainly and cold knife dissection towards the corneal ends. Hyalo-barrier gel was instilled, and copper coil was inserted, high dose estrogen was given for 6 weeks post operatively. Coil was removed after 3 months. She then had frozen embryo transfer with two blastocysts.

This transfer was successful and confirmed twin gestation. However, she had preterm prelabour ruptured membranes at 28 weeks gestation and delivered by Caesarean Section at 29+4 weeks. The birthweights of the babies were normal centiles for that gestation and were discharged home in good condition.

DISCUSSION

Treating patients with Asherman’s syndrome and thin endometrium is an ongoing challenge in the field of Reproductive Medicine.

Although the syndrome has been widely investigated, evidence of both prevention of the syndrome and the ideal treatment are missing.

Surgical management offers favorable fertility outcomes and is often successful in restoring menstruation. Surgical management with hysteroscopic lysis of adhesions is the gold standard for treatment and adopting an office-based approach offers several advantages.

Prevention of reformation of adhesions remains challenging and no single method for preventing recurrence has shown superiority.

Cell-based therapies using endometrial stem/progenitor cells hold promise for future use in regenerating inadequate endometrium.

The recurrence rate following treatment is as high as 33%-66% depending on severity.

CONCLUSION

Increased awareness of the symptoms suggestive of intrauterine adhesive disease, as well as recognition of common causes and preceding events, is crucial for early diagnosis, patient counselling and treatment.

Type of adhesiolysis (versa point vs cold-knife), with judicious use of hyalo-barrier, coil & oestrogen led to success in this challenging case.  

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Unlocking the Future of Health: Longevity Medicine in Maryland

What is Longevity Medicine?

Longevity medicine, also known as anti-aging medicine, is an interdisciplinary field focused on preventing age-related diseases and slowing down the biological processes of aging. Unlike traditional medicine, which treats diseases as they occur, longevity medicine aims to prevent the onset of chronic conditions such as cardiovascular disease, diabetes, and Alzheimer's by addressing the root causes of aging. This is done through personalized treatment plans that often incorporate cutting-edge scientific innovations like gene therapy, regenerative medicine, advanced diagnostics, and lifestyle modifications.

Why Maryland is Becoming a Hub for Longevity Medicine

Maryland is home to several top-tier medical research institutions, including Johns Hopkins University and the National Institutes of Health (NIH). longevity medicine maryland These organizations have been instrumental in the development of medical breakthroughs that form the foundation of longevity medicine. Furthermore, Maryland’s strategic location within the Washington D.C. metro area provides easy access to policymakers, federal funding, and private investments, making it an ideal place for the growth of this innovative medical field.

The state also boasts a thriving biotech sector, with numerous companies focusing on pharmaceuticals, genetics, and medical devices aimed at improving human longevity. Companies like United Therapeutics and Novavax, both based in Maryland, are working on groundbreaking treatments that could significantly enhance human lifespan and healthspan. In addition, Maryland's robust startup ecosystem offers fertile ground for smaller companies focused on developing new therapies that target aging at the molecular level.

Key Approaches in Longevity Medicine

There are several key strategies that longevity medicine employs to promote a longer, healthier life:

Genomics and Personalized Medicine: Thanks to advances in genomic research, doctors can now analyze a person’s genetic makeup to predict their susceptibility to age-related diseases. This allows for the creation of personalized treatment plans that can include medications, dietary changes, and lifestyle adjustments specifically designed to address an individual's unique genetic risks.

Regenerative Medicine: Stem cell therapy and tissue engineering are rapidly evolving fields that play a crucial role in longevity medicine. These technologies aim to repair or replace damaged tissues and organs, effectively slowing down the aging process at the cellular level.

Advanced Diagnostics: New diagnostic tools allow for earlier detection of diseases, which is critical for longevity. Biomarkers for aging, such as telomere length and mitochondrial function, can provide insight into a person’s biological age — often distinct from their chronological age — and help guide preventative treatments.

Lifestyle Interventions: Diet, exercise, sleep, and stress management are all critical factors in longevity medicine. Many of these practices have been scientifically shown to influence biological markers of aging. For example, caloric restriction and intermittent fasting are both associated with improved longevity in various studies.

The Future of Longevity Medicine in Maryland

With the convergence of scientific innovation and increasing public interest in extending both lifespan and healthspan, the future of longevity medicine in Maryland looks promising. As more clinical trials are conducted and more treatments become available, Maryland’s role as a leader in this field will likely grow. The state’s proximity to key regulatory agencies like the Food and Drug Administration (FDA) also positions it as a vital player in the translation of longevity research into real-world applications.

Moreover, Maryland’s aging population stands to benefit from these advances. According to the Maryland Department of Aging, the number of residents aged 60 and older is projected to increase significantly in the coming decades. Testosterone replacement therapy for men This makes the state an important testing ground for longevity medicine, as healthcare providers seek to improve the quality of life for an aging demographic.

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How Medical Tourism is Revolutionizing Healthcare Access Globally

Introduction

Medical tourism, a rapidly growing trend, fundamentally reshapes how people access healthcare worldwide. This phenomenon, which combines medical treatment with travel, is helping patients overcome barriers like cost, waiting times, and limited availability of specific treatments in their home countries. As it gains momentum, medical tourism is also bringing significant changes to the healthcare industry, raising the bar on quality, expanding economic opportunities, and driving cross-border collaboration.

In this blog, we’ll explore the concept of medical tourism, the factors driving its popularity, its benefits, and its broader impact on global healthcare.

What is Medical Tourism?

Medical tourism refers to traveling across international borders to receive medical care. Patients who engage in medical tourism often seek treatments such as surgeries, dental care, fertility treatments, cosmetic surgeries, and even wellness therapies. While historically limited to wealthier individuals, modern developments have made it more accessible to middle-income groups as well. Destinations like India, Thailand, Mexico, and Turkey have become popular hubs for affordable, high-quality healthcare.

The Uptrend of Medical Tourism

Medical tourism is experiencing exponential growth. A report by the Medical Tourism Association estimates that the global medical tourism market is growing at a rate of 15–25% annually. The uptrend is driven by several factors, including the rising cost of healthcare in countries like the U.S., where patients face exorbitant expenses for surgeries and routine procedures. Furthermore, as healthcare systems in many developed countries experience staffing shortages and extended waiting times, patients are increasingly exploring foreign alternatives that offer quicker access to care.

Key Factors Driving the Popularity of Medical Tourism

Several key factors contribute to the popularity of medical tourism:

Cost-Effectiveness:

 One of the main drivers is the significant cost savings that patients can achieve by seeking medical care abroad. In countries like the U.S. or the UK, healthcare is notoriously expensive, and many patients find themselves paying out of pocket due to insurance gaps. Medical tourism destinations often offer the same procedures at a fraction of the cost, making them an attractive option for budget-conscious individuals. For instance, a heart bypass surgery in India could cost 20% of what it would in the U.S., including travel expenses.

Access to Innovative Treatment:

 Many medical tourists seek treatments not available or approved in their home countries. Countries like Germany, South Korea, and Japan are known for offering advanced therapies in fields such as cancer treatment, stem cell therapy, and organ transplants. This access to cutting-edge technologies and therapies is a key motivator for patients willing to travel for medical care.

Combining Healthcare with Travel: 

Another appeal of medical tourism is the opportunity to explore a new destination. Patients who need elective procedures or wellness treatments often turn their medical trips into vacations. For example, countries like Thailand and Costa Rica are known not only for their advanced healthcare facilities but also for their scenic landscapes, cultural experiences, and relaxation resorts. This blend of medical care with leisure activities can turn a stressful medical experience into a rejuvenating one.

Personalized Care and Privacy: 

In many developing countries, the healthcare industry is highly competitive, which pushes hospitals and clinics to offer personalized care and enhanced privacy. High-end medical tourism packages often include concierge services, dedicated healthcare liaisons, and private recovery suites, catering to the needs of high-net-worth individuals or those seeking anonymity during their treatments.

Quality Expertise and Healthcare:

 Countries that are major players in medical tourism are also home to world-class hospitals and highly skilled medical professionals. Facilities in countries such as Singapore, Turkey, and India are accredited by international healthcare accreditation bodies like the Joint Commission International (JCI), ensuring that patients receive high-quality care comparable to what is offered in Western countries. Additionally, many doctors in these destinations are trained in top medical schools around the world, providing patients with peace of mind.

Shorter Wait Time:

 One of the significant advantages medical tourism offers is the ability to bypass long waiting lists. In countries with public healthcare systems like Canada and the UK, patients may wait months for non-emergency surgeries or treatments. By seeking care in countries with private healthcare systems, patients can receive treatments almost immediately, making it an ideal option for those in need of urgent or time-sensitive care.

Get a Vacation and Get Treatment

A unique aspect of medical tourism is the combination of healthcare with travel. Unlike receiving treatment in one's home country, medical tourism offers a chance to recover in a vacation-like environment. Many destinations, such as Bali, Thailand, and Mexico, are not just known for their healthcare but also their beautiful beaches, cultural heritage, and wellness retreats. Patients can enjoy a luxurious recovery while also indulging in tourism activities that promote physical and emotional healing.

Impact on the Healthcare Industry

Medical tourism is not just changing how patients access care; it is also having a profound impact on the healthcare industry.

Competition and Quality Improvement: 

The global competition created by medical tourism pushes healthcare providers to constantly improve their standards of care. Hospitals and clinics in medical tourism hubs aim to provide top-notch facilities, cutting-edge technology, and highly trained staff to attract international patients. This competition helps raise the quality of care both in the destination countries and, indirectly, in patients' home countries as local hospitals strive to retain their clientele.

Economic Development: 

Medical tourism is a major contributor to the economies of many developing countries. Governments are investing heavily in healthcare infrastructure to attract foreign patients, which, in turn, boosts job creation and stimulates other sectors such as hospitality, travel, and retail. For example, countries like Thailand and Malaysia have seen significant economic gains from the influx of medical tourists, helping to boost overall GDP and healthcare exports.

Cross-Border Collaboration: 

The growing trend of medical tourism has led to increased cross-border collaborations between healthcare institutions. These partnerships enable hospitals in different countries to exchange knowledge, share best practices, and collaborate on research and development. Medical tourists can benefit from this collaboration by gaining access to better care and innovative treatments that might not be available domestically.

Domestic Healthcare Improvement:

 In some cases, the rise of medical tourism has had positive ripple effects on the domestic healthcare systems in the destination countries. Investments in private healthcare infrastructure and international patient services often benefit local populations by improving the overall quality of care, modernizing medical facilities, and enhancing physician training. As a result, domestic patients may also gain access to higher standards of care and shorter wait times.

Is Seeking Medical Tourism the Right Choice?

While medical tourism offers numerous benefits, it may not be the right choice for everyone. Patients must weigh the pros and cons before embarking on a journey for medical care.

Pros: 

Cost savings, access to treatments unavailable in one’s home country, and shorter wait times are all significant advantages. Patients who value personalized care, privacy, and the chance to combine medical treatment with a vacation may also find medical tourism appealing.

Cons: 

There are risks associated with medical tourism. These include the potential for complications arising far from home, language barriers, and differences in medical regulations between countries. Patients may also face challenges in follow-up care once they return home. It is crucial for individuals considering medical tourism to thoroughly research the medical provider, the legal environment, and potential risks before making a decision.

Conclusion

Medical tourism is revolutionizing healthcare access across the globe, providing patients with opportunities to seek affordable, high-quality treatment while enjoying the cultural and geographical offerings of new destinations. As the industry continues to grow, it is fostering improvements in medical practices, infrastructure, and economic growth in many regions. However, patients must carefully evaluate their options to ensure a safe and successful medical experience. With the right planning, medical tourism can be a transformative way to access healthcare while exploring the world.

FAQ

What is medical tourism, and why is it growing in popularity?

Medical tourism refers to traveling to another country to receive medical treatment. It has grown in popularity due to factors such as high healthcare costs in some countries, long waiting times for treatment, and access to advanced medical procedures abroad. Patients often find more affordable care with comparable or higher quality and can combine medical procedures with travel experiences in scenic destinations.

What types of treatments do people typically seek through medical tourism?

Common treatments sought through medical tourism include elective surgeries (such as cosmetic surgery and orthopedic procedures), dental treatments, fertility treatments, organ transplants, cardiac surgeries, and wellness therapies. Many people also travel for specialized treatments like cancer therapies, stem cell treatments, and advanced procedures not available or approved in their home countries.

How do patients benefit financially from medical tourism?

One of the primary benefits of medical tourism is the significant cost savings. Treatments abroad can be up to 50–80% cheaper than in countries like the U.S., the UK, or Canada. For example, procedures such as heart surgeries, dental implants, or cosmetic surgeries often cost a fraction of what they would in the patient’s home country, even after accounting for travel and accommodation expenses.

Is medical tourism safe, and how can I choose a reliable medical provider?

While medical tourism can be safe, it is important to thoroughly research the medical provider and the destination before traveling. Look for hospitals or clinics accredited by recognized international bodies like the Joint Commission International (JCI). It’s also a good idea to read reviews from other patients, check the qualifications of the doctors, and ensure the facility follows internationally accepted medical standards. Consulting with your home physician before and after the procedure can also help ensure continuity of care.

What are some potential risks or downsides to medical tourism?

Potential risks of medical tourism include complications during or after the procedure, language barriers, and differences in medical standards or regulations between countries. Follow-up care may also be challenging, especially if the patient experiences complications after returning home. Additionally, patients need to consider the legal protections available in the destination country in case something goes wrong during the treatment. Careful planning and choosing accredited, reputable providers can mitigate some of these risks.

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Dr. Keith Nemec’s Total Health Institute Complaints and Lawsuits 2024

A comprehensive look at controversy, lawsuits, complaints, and growing negative reviews about Total Health Institute reveals a shocking mistrust of patient experiences and legal challenges.

The Total Health Institute (THI) is located in Wheaton, Illinois, and has always been a beacon of hope for people seeking holistic healing and health.

Dr. Keith Nemec established Total Health Institute in 2000. The institute is known for integrating the latest scientific advances with traditional treatments to promote mind, body, and soul wellness.

But this noble cause has caused an uproar of controversy, with a backdrop of litigation, patient complaints, and divided public opinions. In her latest article, Lauren Casper, a famous author and public reviewer, exposed the Total Health Institute, Dr. Keith, and their misdeeds to patients.

Who is Dr. Keith Nemec?

Dr. Nemec received his Bachelor’s degree in human biology, his doctorate at the National University of Health Sciences (though he practices with his Pastoral Medical License), and a master’s degree in Nutritional medicine at Morsani College of Medicine.

He holds Three Fellowships with the American Academy for Anti-Aging Medicine, which include Regenerative Medicine, Stem Cell Therapies, and Integrative Cancer Therapies.

Dr. Nemec is also certified in Peptide Therapy and Fertility. He has published five books: The Perfect Diet, The Environment of Health and Disease, Seven Basic Steps to Total Health, and Total Health = Completeness.

The author has also written numerous health-related articles, such as: “The Single Unifying Cause of All Disease” and “The Answer to Cancer is Found in the Stem Cell”.

Dr. Nemec has hosted the radio program “Your Total Health” on Chicago AM1160 over the past 18 years. She was also regularly a presenter on the talk show “Let’s Talk” in Chicago as a health expert.

Dr. Nemec specializes in neuroimmunology, nutritional medicine, and the biology of stem cells. The main area of focus is how the brain, mind, diet, and lifestyle influence the health of cells, mainly stem cells.

Total Health Institute Complaints

As part of our research into the experience of patients of The Total Health Institute (THI), We spoke to “Alex Johnson” (a pseudonym for privacy reasons). He shared insight about their care, interaction with staff members, and services.

Alex described their excitement when they joined THI. The prospect of an integrated method of healthcare enticed them. However, their experience was soon ruined by their perception of poor conduct from employees. “I was really hoping for a supportive environment, but instead, I encountered staff who were, at times, rude and dismissive,” Alex said, emulating those sentiments in online complaints.

The aspect of finances in the treatment was another area to be argued over by Alex. He was shocked at the cost-intensive nature of treatments and the need to buy supplements from the institute. “It felt like every aspect of my treatment was tied to an additional cost, and the lack of transparency in billing just added to my frustration,” Alex expressed, echoing the concerns about the pricing and billing policies.

As part of our investigation, we talked to another victim, Anthony Bavaro, who provided a shocking account of how his family dealt with THI.

Bavaro was disappointed when he sought alternative treatment at THI to treat his wife’s stage 4 cancer, as well as the lengthy chemotherapy treatment, expecting to receive something other than what was stated by THI. They hoped THI would provide a unique approach to managing the debilitating disease. Instead, they discovered discontent rather than satisfaction. Bavaro reported that, according to their account, Dr. Nemec had given them optimism despite the severity of their illness. Attracted by the assurance of their future, they decided to invest in the institute’s treatment program, which required an upfront payment and registration for several sessions over time.

Anthony Bavaro’swife passed away just a few days after having only attended two sessions.

Deeply horrified, Bavaro found himself disappointed because his attempts to alleviate the financial burden of THI resulting from non-fulfilling therapies with them had fallen in vain. He said they resisted all payments but offered no compensation or closure. This led Bavaro to doubt Dr. Nemec’s motives and suggested that profit over the patient’s care or ethics was placed above all else.

Total Health Institute Lawsuits

The lawsuit against Total Health Institute (THI) brings to light several severe allegations against the facility and its founder, Dr. Keith Nemec. A former patient, identified as Laura McDaniel, has accused the institute of providing ineffective and potentially harmful treatments. McDaniel’s allegations include being misled about the nature of the treatments and being asked to make substantial financial contributions to continue receiving care.

The lawsuit also concerns Dr. Nemec’s qualifications, the accuracy of his representations about his educational background, and the efficacy of the treatments offered at THI. Moreover, regulatory bodies are conducting ongoing investigations into the institute’s practices, explicitly questioning the adequacy of record-keeping and the accuracy of diagnoses made at the facility​.

Another perspective on the lawsuit highlights the complexities surrounding the institute’s use of unverified therapies and misleading promises. The case raises significant questions about the institute’s adherence to medical licensing requirements, particularly regarding treatments licensed medical professionals should administer.

This legal battle scrutinizes Dr. Nemec and his treatment methodologies and involves a group of former patients seeking justice for what they perceive as unethical practices. The lawsuit’s outcomes could have broader implications for the alternative healthcare sector, emphasizing the need for transparency and adherence to regulatory standards.​

These developments of THI led patients to consider alternative healthcare options, underscoring the importance of thorough research and due diligence when selecting healthcare providers and treatments.

Merged To Revolution New Medicine

In the wake of lawsuits and complaints, Total Health Institute has merged its name with Revolution New Medicine, situated at 23W525 St Charles Rd, Carol Stream, IL 60188. The joint ventures or merging of Total Health Institute appears to be an element of a larger plan to change the focus of their business and perhaps rethink their approach to alternative health and therapies.

Revolution New Medicine promotes holistic healing, providing various treatments, including detoxification, nutrition, and holistic therapies, to address the root cause of health problems. The newly rebranded company, under the direction of Dr. Keith Nemec, places the importance of optimizing the brain as one of the pillars of the treatment approach.

The approach is based on the centrality of the brain in ensuring health throughout the various body systems and demonstrates the interconnectedness of emotional, mental, and physical well-being.

Revolution New Medicine advocates for the treatment of brain disorders, blockages, or inflammation as the key to resolving the wide range of health problems, ranging from mental and emotional health issues to physical ailments.

The pivotal move towards Revolution New Medicine seems to be an effort to overcome the uncertainties and legal issues facing Total Health Institute and strengthen its dedication to offering alternative health solutions.

Focusing on optimizing brain function and taking a comprehensive approach to health reflects the ongoing commitment to treating the root causes of illness instead of just treating the symptoms.

Conclusion

This transformation can be seen as an attempt to distance itself from a troubled past, while skeptics might interpret it as an effort to salvage its reputation amidst growing mistrust.

This shift emphasizes addressing the fundamental causes of health issues and optimizing patient care, though it remains to be seen whether it can rebuild the tarnished trust.

[sciivfhospitaldelhi]

Stem Cell Therapy in IVF: A Promising Future for Fertility Treatments

In recent years, stem cell therapy has emerged as a revolutionary development in various medical fields, including fertility treatments. For couples struggling with infertility, the advancements in stem cell therapy offer new hope and potential solutions.

Understanding Stem Cell Therapy in IVF

Stem cells are unique cells with the ability to develop into different types of cells in the body. Their regenerative properties have made them a significant focus of medical research, particularly in treating diseases and repairing damaged tissues. In the context of IVF, stem cell therapy aims to improve fertility outcomes by enhancing ovarian function and egg quality.

How Stem Cell Therapy Works in IVF

Ovarian Rejuvenation: Stem cell therapy can potentially rejuvenate aging ovaries by regenerating ovarian tissues. This process involves injecting stem cells into the ovaries to stimulate the production of healthy eggs, thereby increasing the chances of successful fertilization.

Improving Egg Quality: Poor egg quality is a common cause of infertility. Stem cells can help improve the quality of eggs by repairing damaged cells and promoting the development of healthy eggs.

Endometrial Regeneration: A healthy endometrium is crucial for embryo implantation. Stem cell therapy can assist in regenerating the endometrial lining, creating a more favorable environment for embryo implantation and growth.

The Role of SCI IVF Hospital and Other Leading IVF Clinics in Delhi

Delhi is home to some of the most advanced and reputable IVF clinics and hospitals in India. Among them, SCI IVF Hospital stands out for its commitment to incorporating cutting-edge technologies and treatments, including stem cell therapy, to enhance fertility outcomes.

SCI IVF Hospital

SCI IVF Hospital in Delhi is renowned for its state-of-the-art facilities and a team of highly experienced IVF doctors. The hospital is at the forefront of adopting innovative fertility treatments, making it a preferred choice for couples seeking advanced reproductive solutions. The expertise of the IVF doctors at SCI IVF Hospital, combined with their compassionate approach, ensures personalized care and high success rates.

The Future of Stem Cell Therapy in IVF

The potential of stem cell therapy in improving fertility outcomes is immense. Ongoing research and clinical trials continue to explore new ways to harness the regenerative power of stem cells to address infertility. As the technology advances, it is expected that stem cell therapy will become more refined and accessible, offering even higher success rates for couples undergoing IVF treatments.

Leading IVF hospital in Delhi like SCI IVF Hospital are pioneering the use of stem cell therapy to enhance fertility treatments. The integration of this cutting-edge therapy into their practice signifies a promising future for those struggling with infertility.

Conclusion

Stem cell therapy represents a significant advancement in the field of IVF, offering new hope for couples facing infertility challenges. With leading IVF clinic in Delhi, such as SCI IVF Hospital, embracing this innovative treatment, the future of fertility treatments looks promising. For those seeking advanced and effective solutions, consulting with a best IVF doctor in Delhi may be the first step towards realizing their dream of parenthood.

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The Dominance of North America in the Biotechnology Market

Introduction:

North America has established itself as a dominant force in the biotechnology market, leading in research and development and shaping global trends and advancements in the field.

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This leadership is attributed to several key factors, including:

1. Research and Development (R&D) Infrastructure:

North America boasts world-renowned universities, research institutes, and biotech hubs such as Silicon Valley, Boston, and San Diego, which provide a fertile ground for innovation and attract top talent 

These regions foster collaboration between scientists, entrepreneurs, and investors, driving the pace of biotechnological advancements.

2. Government Support and Regulatory Environment:

The region's policies encourage innovation, protect intellectual property rights, and streamline regulatory processes, nurturing biotechnology startups and facilitating market entry for new products 

3. Venture Capital and Investment:

North America attracts significant venture capital investment, enabling biotech startups to translate research discoveries into commercially viable products, fueling R&D efforts and accelerating the pace of innovation.

4. Strong Pharmaceutical and Healthcare Sectors:

The established pharmaceutical industry and robust healthcare infrastructure in North America create a demand for biotechnological solutions, ranging from personalized medicine to novel drug therapies and medical diagnostics 

5. Focus on Sustainability and Bio-based Products:

The region's increasing awareness of environmental sustainability has spurred the development of bio-based products, renewable energy technologies, and eco-friendly agricultural practices, positioning North America as a leader in sustainable biotechnology solutions 

Sectoral Breakdown: Pharmaceuticals, Agriculture, and Beyond

Pharmaceuticals:

North America dominates the global biopharmaceutical market, with a significant share of revenue attributed to innovative biologics and personalized medicine.

Agriculture and Agri-tech:

Biotechnology plays a crucial role in enhancing agricultural productivity, sustainability, and food security in North America. The region's biotech firms are at the forefront of developing genetically modified crops, biopesticides, and precision agriculture technologies.

Industrial Biotechnology:

North America leads in industrial biotechnology, focusing on biofuels, biodegradable plastics, and biochemicals derived from renewable sources, supporting the transition towards a bio-based economy and reducing reliance on fossil fuels.

Challenges and Opportunities

While North America enjoys a leadership position in biotechnology, the sector faces challenges such as regulatory hurdles, the cost of innovation, and ethical and societal concerns. However, these challenges also present opportunities for growth and collaboration. By addressing regulatory concerns, enhancing funding mechanisms, and fostering public trust through transparent communication, North America can sustain its leadership in biotechnology while navigating the evolving landscape of ethical and regulatory considerations.

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Future Outlook: Driving Innovation Forward

Looking ahead, North America's biotechnology sector is poised for continued growth and innovation. Emerging technologies such as CRISPR gene editing, RNA interference, and stem cell therapies hold promise for transforming healthcare and agriculture. Moreover, advancements in artificial intelligence and machine learning are revolutionizing drug discovery processes and personalized medicine. Collaborations between academia, industry, and government stakeholders will be crucial in harnessing these technologies to address global challenges such as climate change, pandemics, and food security. By fostering an ecosystem that encourages risk-taking, innovation, and responsible stewardship of biotechnological advancements, North America can maintain its leadership role in shaping the future of biotechnology on a global scale.

Conclusion:

North America stands at the forefront of the biotechnology revolution, driven by a convergence of scientific expertise, entrepreneurial spirit, and supportive ecosystems. As the region continues to push the boundaries of scientific discovery and technological innovation, the impact of its biotechnological advancements will reverberate globally, shaping industries, improving lives, and paving the way for a sustainable and prosperous future.

[surrogacycentre-india]

Stem Cell Treatments in IVF

In recent years, the field of assisted reproductive technology has witnessed remarkable advancements, with stem cell treatments emerging as a promising solution for enhancing fertility outcomes. At the forefront of these innovations is SCI IVF Hospital, widely recognized as the best IVF hospital in Delhi NCR.

Understanding Stem Cell Treatments in IVF

Stem cell treatments involve the use of regenerative cells to repair or replace damaged tissues. In the context of IVF, stem cells can be utilized to rejuvenate ovarian function, improve egg quality, and enhance endometrial receptivity, thereby increasing the chances of a successful pregnancy. Here are some key applications of stem cell treatments in IVF:

Ovarian Rejuvenation: For women with diminished ovarian reserve or poor egg quality, stem cell therapy offers a ray of hope. By injecting stem cells into the ovaries, it is possible to stimulate the growth of new, healthy eggs, improving fertility prospects for women who might otherwise have limited options.

Endometrial Enhancement: A receptive endometrium is crucial for embryo implantation. Stem cell treatments can improve the thickness and health of the endometrial lining, creating a more favorable environment for embryo implantation and reducing the likelihood of implantation failures.

Repairing Uterine Damage: Stem cells have the potential to repair uterine damage caused by conditions such as Asherman's syndrome or severe endometriosis, which can severely impact fertility. By regenerating healthy uterine tissue, stem cell therapy can restore normal uterine function and increase the chances of a successful pregnancy.

Why Choose SCI IVF Hospital?

When considering stem cell treatments for IVF, selecting a reputable and experienced hospital is crucial. SCI IVF Hospital, renowned as the best IVF hospital in Delhi NCR, offers cutting-edge treatments and personalized care to ensure the highest chances of success. Here are some reasons why SCI IVF Hospital stands out:

Expertise and Experience: SCI IVF Hospital boasts a team of highly skilled and experienced fertility specialists who are pioneers in the field of stem cell treatments. Their expertise ensures that patients receive the most advanced and effective treatments available.

State-of-the-Art Facilities: The hospital is equipped with state-of-the-art technology and modern infrastructure, providing a conducive environment for advanced fertility treatments. The use of cutting-edge equipment enhances the precision and success rates of stem cell therapies.

Comprehensive Care: SCI IVF Hospital offers a holistic approach to fertility treatment, addressing both the physical and emotional needs of patients. The compassionate and supportive staff ensures that patients receive comprehensive care throughout their IVF journey.

IVF Treatment Cost in Delhi

The cost of IVF treatment in Delhi can vary depending on several factors, including the type of treatment, the complexity of the case, and the specific requirements of the patient. At SCI IVF Hospital, the cost of IVF treatment is transparent and competitive, ensuring that patients receive high-quality care without any hidden expenses.

Stem cell treatments, being an advanced procedure, may add to the overall cost of IVF. However, the potential benefits and improved success rates often justify the investment. It is advisable for patients to consult with the experts at SCI IVF Hospital to get a detailed understanding of the costs involved and the payment options available.

Conclusion

Stem cell treatments represent a groundbreaking advancement in the field of IVF, offering new hope to couples struggling with infertility. SCI IVF Hospital, the best IVF hospital in Delhi NCR, is at the forefront of this innovation, providing cutting-edge treatments and comprehensive care to maximize the chances of a successful pregnancy. For those seeking advanced fertility solutions, SCI IVF Hospital stands as a beacon of excellence and hope in the journey towards parenthood.

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Leukemia in Children

Introduction

Leukemia in children presents a formidable challenge, demanding meticulous management and treatment. This detailed discussion aims to devolve into various facets of childhood leukemia, encompassing its definition, types, causes, risk factors, symptoms, diagnosis, treatment modalities, potential complications, preventive measures, and strategies for supporting a child living with leukemia.

Understanding Leukemia in Children

1. Definition

Leukemia is a hematological malignancy affecting the blood and bone marrow. Its prominence in childhood stems from the rapid proliferation of abnormal blood cells, disrupting the delicate balance within the body.

2. Types of Blood Cells

Understanding the roles of

Red blood cells (erythrocytes),

2.platelets (thrombocytes), and

3.white blood cells (leukocytes)

Is fundamental. An imbalance in these cells results in a spectrum of symptoms, from anemia to increased infection susceptibility.

3. Types of Leukemia

. Acute Lymphocytic Leukemia (ALL): Predominant in children.

Acute Myelogenous Leukemia (AML): The second most common type.

Hybrid or Mixed Lineage Leukemia: A rare amalgamation of ALL and AML.

Chronic Myelogenous Leukemia (CML): Uncommon in children.

Chronic Lymphocytic Leukemia (CLL): Extremely rare in pediatric cases.

Juvenile Myelomonocytic Leukemia (JMML): A rare type with unique growth characteristics.

Causes and Risk Factors

1. Causes

The exact etiology of childhood leukemia remains elusive. Genetic mutations in bone marrow cell genes may occur sporadically or, in some instances, be inherited.

2. Risk Factors

Exposure to Radiation.

Particularly high levels.

Inherited Syndromes.

Down syndrome.

Li-Fraumeni syndrome.

Immune System Conditions.

Inherited disorders affecting immune function.

Family History.

Having a sibling with leukemia elevates the risk.

Symptoms of Leukemia in Children

A diverse array of symptoms underscores leukemia’s impact on children, including;

.Pale skin

. Fatigue

.Dizziness

.Headaches

.Shortness of breath

.Frequent infections

.Fever

. Easy bruising

.Bleeding

.Bone or Joint pain, and

.Abdominal swelling.

Diagnosis:

1. Procedures:

.Blood Tests (Complete Blood Count — CBC): Essential for initial assessment.

Bone Marrow Aspiration or Biopsy: Crucial in detecting leukemia cells.

Lab Tests: Precisely determine leukemia type.

Diagnostic Imaging: X-rays, ultrasound,

lymph node biopsy, and

Lumbar puncture offer a comprehensive diagnostic perspective.

2. Classification

Unlike other cancers, leukemia is not staged but rather classified into groups, subtypes, or both based on type and specific characteristics, aiding in targeted treatment approaches.

Treatment Options:

1. Primary Treatments:

Blood Transfusions: Address low blood counts, bleeding, or infections.

Chemotherapy: The mainstay, killing or inhibiting cancer cells.

Radiation Therapy: High-energy X-rays to target and eradicate cancer cells.

Stem Cell Transplant: Involves high-dose chemotherapy followed by stem cell replacement.

Targeted Therapy: Specific medications tailored to combat certain types of leukemia.

Immunotherapy: Enhances the body’s immune system to combat cancer cells.

Complications:

1. Short-term:

Serious Infections: Resulting from compromised immune function.

Severe Bleeding: A consequence of low platelet levels.

Thickened Blood: Accumulation of leukemia cells in the bloodstream.

2. Long-term:

Leukemia Recurrence: A persistent concern.

Development of Other Cancers: A potential consequence of treatment.

Heart and Lung Problems: Arising from the impact of leukemia or its treatment.

Learning Issues and Growth Delays: Impacts on cognitive development and physical growth.

Fertility Problems and Bone Issues: Osteoporosis as a potential long-term complication.

Prevention:

Preventing childhood leukemia remains challenging, with a focus on caution regarding unnecessary exposure to radiation, especially in diagnostic procedures involving pregnant women and children.

Supporting a Child with Leukemia:

1. Ongoing Care:

Regular visits to oncologists and healthcare providers are crucial for monitoring and addressing emerging issues.

2. Balanced Lifestyle:

Managing eating difficulties and encouraging appropriate exercise play a vital role in supporting overall health.

3. Emotional Support:

Seeking counseling or participating in support groups helps both the child and their family navigate the emotional challenges associated with leukemia.

4. Follow-up Appointments:

Attending all scheduled appointments ensures continuous monitoring and timely intervention if complications arise.

When to Contact Healthcare Provider:

Prompt communication with healthcare providers is essential if the child experiences fever, worsening symptoms, new symptoms, or side effects from treatment.

Key Points Summary:

Leukemia necessitates a comprehensive approach, involving diagnosis, tailored treatment, and ongoing monitoring.

Varied symptoms demand timely medical attention for an optimal prognosis.

Treatment modalities, including chemotherapy and stem cell transplant, are tailored to the specific leukemia type.

Complications, both short-term and long-term, underscore the importance of ongoing follow-up care.

Prevention is limited, with a focus on minimizing unnecessary radiation exposure.

Comprehensive support, encompassing medical, emotional, and lifestyle aspects, is essential for the child’s well-being.

Next Steps:

1. Follow-up Care:

Continued regular check-ups and imaging tests remain integral to post-treatment monitoring.

2. Communication:

Maintaining open and transparent communication with healthcare providers ensures timely intervention if issues arise.

3. Research:

Inquiring about ongoing clinical trials or new treatments enables families to stay informed about emerging possibilities.

Conclusion:

Childhood leukemia mandates a collaborative effort from medical professionals, caregivers, and support networks to optimize outcomes and enhance the quality of life for affected children. As the landscape of pediatric oncology evolves, the commitment to advancing treatment options and minimizing the impact of complications remains paramount, offering hope for a brighter future for children navigating the complexities of leukemia.

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[medlineacademics]

Embryology Courses in India: Things you need to know!

Why do we need Embryology Courses in India?

The area of biology known as embryology is concerned with examining how embryos develop from the time an egg is fertilised until the foetus stage. Due to its applications in the fields of genetics, stem cell research, and assisted reproductive technologies, embryology has recently grown in importance as a subject of study. Due to the rising demand for infertility treatments and the necessity for research in this area, there is an increasing demand in India for training in embryology.

An embryologist is an embryologist, who helps use sperm and eggs to produce embryos outside the womb. Couples who have difficulty conceiving naturally may need help from an embryologist.

An undergraduate diploma in biological technology is needed for entry into the sector of embryology, that's accompanied through a postgraduate diploma, ideally in biotechnology, assisted reproductive generation, or embryology. To turn out to be a competent embryologist, one need to entire a defined curriculum for scientists that consists of 1 or 2 years of tutorial, theoretical, and realistic schooling in embryology. Of direction, revel in is a need to for skills.

How does this training help?

In India, the number of couples searching for infertility treatments has drastically multiplied in current years. As a end result, there's an increasing want for embryologists who are professional within the most recent techniques and equipment. Training in embryology can supply humans the records and skills needed to carry out infertility treatments like intracytoplasmic sperm injection (ICSI) and in vitro fertilisation (IVF) (ICSI).

Embryology is now a crucial part of research in developmental biology, genetics, and stem cellular research, amongst different fields. Understanding embryonic improvement and its underlying standards with the useful resource of expertise in embryology can assist researchers find new healing procedures and therapies for a number of illnesses.

Clinics that concentrate on ART are essential to the system of treating infertility. To assure positive consequences, it's miles essential to guarantee the calibre of the offerings presented by those clinics. Individuals can accumulate the abilities and records had to uphold the very best ranges of high-quality and protection in ART facilities via schooling in embryology.

Students receiving stem cell training develop a thorough understanding of the methods and equipment used in the laboratory to successfully fertilize, grow and transfer embryos in ART.

Students have a wide understanding of the fundamental standards of embryology during their clinical embryology programme, which include fertilisation, early embryonic development, and implantation. Students gain from having this know-how when they perform every day duties in ART labs, together with managing oocytes, sperm, and embryos.

Students find out about the significance of quality assurance in ART throughout their schooling in embryology courses in Bangalore, such as the protection of device, lab safety, and excellent manipulate. This statistic permits students to uphold the greatest levels of satisfactory and safety within the lab, assuring the fulfillment of ART operations.

How Medline Academics will help you in this journey? Embryology Course Details

Access to a wide range of biomedical literature, including research articles, journals, conference proceedings, and ebook chapters, is made possible thru the full-size on-line database Medline Academics. Access to a massive library of educational materials on embryology is available through our institute and e-getting to know platform. These materials include e book chapters, posted studies papers and critiques, as well as conference proceedings. These sources offer modern and complete facts at the maximum latest theories, methods, and improvements inside the problem of embryology. This access can substantially assist embryology trainees in enhancing their information and information within the difficulty even as retaining up with the maximum latest improvements.

Trainees in embryology can benefit from the thorough literature opinions and crucial assessment of available studies research completed by using Medline Academics. This method can assist college students in gaining a deeper comprehension of the research strategies carried out within the situation and assist them come to properly-informed ideas and conclusions.

For embryology trainees, Medline Academics can be a priceless useful resource as it offers get right of entry to super educational literature, state-of-the-art search options, gear for critical evaluation and literature evaluations, quotation control options, and possibilities for networking and collaboration with other researchers within the field.

Students who get hold of training in medical embryology gain a thorough know-how of the principles of embryology, the laboratory approaches utilised in ART, as well as the considered necessary technical trouble-fixing talents and laboratory control competencies. Students can achieve professions in fertility and reproductive remedy with the use of these information and talent sets, giving them many alternatives for development and success. A medical embryology course with Medline Academics can enhance your credentials and growth your marketability for jobs. It can also resource to your profession advancement with the aid of showcasing your willpower to lifelong gaining knowledge of and expert boom. Know about our embryology course fees and details on our official website.

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Dr. Keith Nemec’s Total Health Institute Complaints and Lawsuits 2024

A comprehensive look at controversy, lawsuits, complaints, and growing negative reviews about Total Health Institute reveals a shocking mistrust of patient experiences and legal challenges.

The Total Health Institute (THI) is located in Wheaton, Illinois, and has always been a beacon of hope for people seeking holistic healing and health.

Dr. Keith Nemec established Total Health Institute in 2000. The institute is known for integrating the latest scientific advances with traditional treatments to promote mind, body, and soul wellness.

But, under this noble cause, an uproar of controversy develops, with a backdrop of litigation, patient complaints, and divided public opinions.

Who is Dr. Keith Nemec?

Dr. Keith Nemec qualifies as a D.PSc., MS, FAARFM FICT, FSCT, as Clinic Director for Revolution New Medicine. For 40 years, he has practiced holistic and alternative medicine and worked with over 10,000 patients.

Dr. Nemec received his Bachelor’s degree in human biology, later his doctorate at the National University of Health Sciences (though Dr. Nemec practices with his Pastoral Medical License), and a master’s degree in Nutritional medicine at Morsani College of Medicine.

He holds Three Fellowships with the American Academy for Anti-Aging Medicine. The fellowships include Regenerative Medicine, Stem Cell Therapies, and Integrative Cancer Therapies.

Dr. Nemec is also certified in Peptide Therapy and Fertility. He has published five books: The Perfect Diet, The Environment of Health and Disease, Seven Basic Steps to Total Health, and Total Health = Completeness.

The author has also written numerous health-related articles, such as: “The Single Unifying Cause of All Disease” and “The Answer to Cancer is Found in the Stem Cell”.

Dr. Nemec has hosted the radio program “Your Total Health” on Chicago AM1160 over the past 18 years. She was also regularly a presenter on the talk show “Let’s Talk” in Chicago as a health expert.

Dr. Nemec specializes in neuroimmunology, nutritional medicine, and the biology of stem cells. The main area of focus is how the brain, mind, diet, and lifestyle influence the health of cells, mainly stem cells.

Total Health Institute Complaints

As part of our research into the experience of patients of The Total Health Institute (THI), We spoke to “Alex Johnson” (a pseudonym for privacy reasons). He shared insight about their care and interaction with staff members and the services.

Alex described their excitement when they joined THI. The prospect of an integrated method of healthcare enticed them. But their experience soon was ruined by their perception of poor conduct from employees. “I was really hoping for a supportive environment, but instead, I encountered staff who were, at times, rude and dismissive,” Alex said, emulating those sentiments in online complaints.

The aspect of finances in the treatment was another area to be argued over by Alex. He was shocked at the cost-intensive nature of treatments and the need to buy supplements from the institute. “It felt like every aspect of my treatment was tied to an additional cost, and the lack of transparency in billing just added to my frustration,” Alex expressed, echoing the concerns about the pricing and billing policies.

As part of our investigation, we talked to another victim, Anthony Bavaro, who provided a shocking account of how his family dealt with THI.

Bavaro was disappointed when he sought alternative treatment at THI to treat his wife’s stage 4 cancer, as well as the lengthy chemotherapy treatment, expecting to receive something other than what was stated by THI. They hoped THI would provide a unique approach to managing the debilitating disease. Instead, they discovered discontent rather than satisfaction. Bavaro reported that, according to their account, Dr. Nemec had given them optimism despite the severity of their illness. Attracted by the assurance of their future, they decided to invest in the institute’s treatment program, which required an upfront payment and registration for several sessions over time.

Anthony Bavaro’swife passed away just a few days after having only attended two sessions.

Deeply horrified, Bavaro found himself disappointed because his attempts to alleviate the financial burden of THI resulting from non-fulfilling therapies with them had fallen in vain. He said they resisted all payments but offered no compensation or closure. This led Bavaro to doubt Dr. Nemec’s motives and suggested that profit over the patient’s care or ethics was placed above all else.

Total Health Institute Lawsuits

The lawsuit against Total Health Institute (THI) brings to light several severe allegations against the facility and its founder, Dr. Keith Nemec. A former patient, identified as Laura McDaniel, has accused the institute of providing ineffective and potentially harmful treatments. McDaniel’s allegations include being misled about the nature of the treatments and being asked to make substantial financial contributions to continue receiving care.

The lawsuit also concerns Dr. Nemec’s qualifications, the accuracy of his representations about his educational background, and the efficacy of the treatments offered at THI. Moreover, regulatory bodies are conducting ongoing investigations into the institute’s practices, explicitly questioning the adequacy of record-keeping and the accuracy of diagnoses made at the facility​.

Another perspective on the lawsuit highlights the complexities surrounding the institute’s use of unverified therapies and misleading promises. The case raises significant questions about the institute’s adherence to medical licensing requirements, particularly regarding treatments licensed medical professionals should administer.

This legal battle scrutinizes Dr. Nemec and his treatment methodologies and involves a group of former patients seeking justice for what they perceive as unethical practices. The lawsuit’s outcomes could have broader implications for the alternative healthcare sector, emphasizing the need for transparency and adherence to regulatory standards.​

These developments of THI led patients to consider alternative healthcare options, underscoring the importance of thorough research and due diligence when selecting healthcare providers and treatments.

Merged To Revolution New Medicine

In the wake of lawsuits and complaints, Total Health Institute has merged its name with Revolution New Medicine, situated at 23W525 St Charles Rd, Carol Stream, IL 60188. The joint ventures or merging of Total Health Institute appears to be an element of a larger plan to change the focus of their business and perhaps rethink their approach to alternative health and therapies.

Revolution New Medicine promotes holistic healing, providing various treatments, including detoxification, nutrition, and holistic therapies, to address the root cause of health problems. The newly rebranded company, under the direction of Dr. Keith Nemec, places the importance of optimizing the brain as one of the pillars of the treatment approach.

The approach is based on the centrality of the brain in ensuring health throughout the various body systems and demonstrates the interconnectedness of emotional, mental, and physical well-being.

Revolution New Medicine advocates for the treatment of brain disorders, blockages, or inflammation as the key to resolving the wide range of health problems, ranging from mental and emotional health issues to physical ailments.

The pivotal move towards Revolution New Medicine seems to be an effort to break over the uncertainties and legal issues facing Total Health Institute, aiming to strengthen its dedication to offering alternative health solutions.

Focusing on optimizing brain function and a comprehensive approach to health reflects the ongoing commitment to treat the root causes of illness instead of just treating the signs.

Conclusion

This transformation can be seen as an attempt to distance itself from a troubled past, while skeptics might interpret it as an effort to salvage its reputation amidst growing mistrust.

This shift emphasizes addressing the fundamental causes of health issues and optimizing patient care, though it remains to be seen whether it can rebuild the tarnished trust.

[nursingscience]

Understanding Stem Cells

Stem cells, known as “குருத்தணுக்கள்” in Tamil, are a type of cell in the human body that can develop into many different cell types, from muscle cells to brain cells. They are unique because they have the potential to develop into specialized cells and can divide and renew themselves for long periods. Stem cells are essential for daily health and regeneration, as they can differentiate to perform specific functions like beating of the heart, thinking in the brain, filtering blood in the kidneys, and repairing tissues like skin.

The unique responsibility of stem cells is to generate other types of cells. When stem cells divide, they can either produce more stem cells or different types of cells with specialized functions. For example, stem cells in the skin can create more skin cells or other types of specialized skin cells responsible for functions like producing melanin, which gives skin its color.

Stem cells are crucial because when we get injured or sick, our cells can get damaged or die. In such cases, stem cells activate to repair damaged tissues and replace dead cells. This process keeps us healthy and slows down aging, acting like a specialized medical unit within our bodies.

There are various types of stem cells, and scientists say that every organ in our body has its own specific stem cells. For instance, our blood is made by hematopoietic (blood-forming) stem cells. Moreover, stem cells are present in the human body from early developmental stages.

When scientists grow these cells outside the body, they are called “embryonic” stem cells. The reason scientists are so interested in researching embryonic stem cells is that they naturally create every organ and tissue during human development. Unlike mature stem cells, embryonic stem cells can easily form hundreds of different types of cells in the body, such as blood, bone, skin, and brain cells. They can also naturally form not just cells but tissues and organs, which mature stem cells cannot do.

Embryonic stem cells have a higher capacity to repair diseased organs compared to other stem cells. Embryonic stem cells used in research are typically derived from unused embryos from fertility treatments that are a few days old.

Induced pluripotent stem cells (iPSCs or IPS) are a new type of stem cell discovered by scientists and doctors. They are excited about iPSCs because they possess almost all the properties of embryonic stem cells but are not taken from embryos. This means there are no ethical concerns in using iPSCs. Additionally, when iPSCs are derived from a patient’s own cells, they are less likely to be rejected by the immune system when reintroduced, which is a significant issue in stem cell therapy.

The future of stem cell therapy is promising, but before it becomes widely used, there are challenges to overcome. These include the risk of stem cells causing cancerous growths and the possibility of being rejected by the body’s immune system. However, stem cells have the potential to revolutionize medicine.

Currently, only a few stem cell therapies have been proven safe and effective, such as bone marrow transplants. While these treatments are gaining attention in the media, especially among celebrities and athletes, scientists and doctors caution patients about the safety and efficacy of unproven stem cell treatments. There have been cases of patients dying from such treatments. Therefore, doctors recommend considering stem cell therapies as a last resort.

Significant discoveries in stem cell research include Sir John Gurdon’s work in 1962, where he replaced the nucleus of a frog’s egg cell with the nucleus from a tadpole’s intestinal cell, demonstrating that the differentiated cell still had the capacity to form every cell in the body. This laid the groundwork for reproductive cloning, leading to the creation of Dolly the sheep. Another milestone was the cultivation of mouse embryonic stem cells in 1981, followed by human embryonic stem cells. A major breakthrough was achieved when Shinya Yamanaka and his colleagues introduced a set of transcription factors that could induce somatic cells to become pluripotent stem cells. For this discovery, Yamanaka was awarded the Nobel Prize in Medicine in 2012, along with Sir John Gurdon.

ஸ்டெம் செல்கள் (குருத்தணுக்கள்) என்றால் என்ன?

மனித உடலில் தினசரி ஆரோக்யத்திற்கு தேவையான நூற்றுக்கணக்கான வகை உயிரணுக்கள் உள்ளன.

இந்த உயிரணுக்களின் பொறுப்பு நம் உடலை செயல்பட வைப்பதாகும் – ●இதயத்தை துடிக்க வைப்பது, ●மூளையை சிந்திக்க வைப்பது, ●சிறுநீரகத்தை ●இரத்தம் சுத்திகரிக்க வைப்பது, ●பழைய தோல் உதிரும் பொழுது ●புதிய தோல் உண்டாக்குவது போன்ற பல செயல்கள். குருத்தணுக்களின் தனி பொறுப்பு என்னவென்றால் பிற அனைத்து உயிரணுக்களையும் உருவாக்குவது. குருத்தணுக்கள் பிற உயிரணுக்களின் சுரபியாகும். குருத்தணுக்கள் பெருகும் பொழுது அவை மேலும் பல குருத்தணுக்களையோ அல்லது வேறு வகை உயிரணுக்கள் பலவற்றையோ உருவாக்க கூடியவை. Example உதாரணமாக, தோலில் இருக்கும் குருத்தணுக்கள் மேலும் பல தோல் குருத்தணுக்களையோ அல்லது பிற விசேஷ கடமை கொண்ட தோல் உயிரணுக்களையோ உருவாக்க கூடியவை.

விசேஷ கடமைக்கு ஓர் உதாரணம் தோலுக்கு கருமை தரும் மெலனின் எனப்படும் சாயம் செய்வது.

குருத்தணுக்கள் ஏன் முக்கியமானவை?

●நாம் காயப்படும்பொழுதோ ●அல்லது ●நோய்வாய்ப்படும் பொழுதோ ■நமது உயிரணுக்களும் காயப்படவோ இறக்கவோ நேரிடுகின்றது. ■

●இது நிகழும்பொழுது, குருத்தணுக்கள் செயல்படுத்தப்படுகின்றன.●

உடலில் காயப்பட்ட திசுக்களை சரிபார்ப்பதும்

இறந்த உயிரணுக்களுக்கு மாற்று உண்டாக்குவதுமே குருத்தணுக்களுக்கு நிர்ணயிக்கப்பட்ட வேலையாகும்.

*இச்செயல்களால் குருத்தணுக்கள் நம்���ை ஆரோக்கியமாக வைத்து நம் உடலை வேகமாக மூப்படையாமல் பார்த்துக்கொள்கின்றன.

ஆகையால்

*குருத்தணுக்கள் நம் உடலின் பிரத்தியேகமான நுண்ணிய மருத்துவப்படை போல செயல்படுகின்றன. ••○○○○○○□■●

குருத்தணுக்கள் என்னென்ன வகைப்படும்?

குருத்தணுக்கள் பல்வேறு வடிவங்களில் இருக்கின்றன.

விஞ்ஞானிகள் கூற்றுப்படி நம் உடலின் ஒவ்வொரு உறுப்பிற்கும் அதன் பிரத்தியேக குருத்தணுக்கள் உள்ளன.

உதாரணமாக, ●நமது இரத்தம், இரத்த குருத்தணுக்களால் (கிரேக்க மொழி: ஹெமடோபொயடிக்/இரத்தம்-உண்டாக்கும்) செய்யப்படுகிறது.

இதுமட்டுமல்லாது,

குருத்தணுக்கள் மனித உடலின் ஆரம்பகால வளர்ச்சி நிலைகளிலிருந்தே இருந்து வருகின்றன.

*இந்த குருத்தணுக்களை உடலுக்கு வெளியே விஞ்ஞானிகள் வளர்க்கும்பொழுது

அவைகளை

*“கரு”*●●●●●●●●□□□■■■■■

(எம்ப்ரியோனிக்) குருத்தணுக்கள் என்று அழைக்கின்றனர்.

விஞ்ஞானிகள் கரு குருத்தணுக்களை கண்டு வியந்து ஆராய்ச்சி செய்யக்காரணமாயிருப்பது வேறொன்றுமல்ல;

அவைகளின் இயற்கை வேலையே மனித வளர்ச்சியின்போது உடலின் ஒவ்வொரு உறுப்பு மற்றும் திசுவின் கட்டமைப்பை உருவாக்குவதாய் இருப்பது தான். இதனால் என்ன பயன் என்றால்,...?????.

●முதிர்ந்த குருத்தணுக்கள் போலல்லாது,

கரு குருத்தணுக்கள் உடலின் மற்ற நூற்றுக்கணக்கான வகை உயிரணுக்களை எளிதில் உருவாக்க கூடியவை.

உதாரணமாக, இரத்த குருத்தணுக்களால் இரத்த வகை உயிரணுக்களை மட்டுமே செய்ய முடியும்; ஆனால் கரு குருத்தணுக்களால்

●இரத்த வகை, ●எலும்பு வகை, ●தோல் வகை, ●மூளை வகை மற்றும் பல வகை உயிரணுக்களையும் உருவாக்க முடியும்.

மேலும், கரு குருத்தணுக்களால் இயற்கையாகவே உயிரணுக்கள் மட்டுமல்லாது, ■555■55■திசுக்கள் மற்றும் உறுப்புகளையும் கூட உருவாக்க இயலும்

ஆனால் முதிர்ந்த குருத்தணுக்களால் இது இயலாது. இதன் பொருள் என்னவென்றால், மற்ற குருத்தணுக்களோடு ஒப்பிடுகையில்

கரு குருத்தணுக்களுக்கு நோயுற்ற உறுப்புகளை சரிபார்பதில் அதிகத் திறன் உள்ளது. கருத்தரிப்பு சிகிச்சை முடிவுற்று உபயோகமின்றி இருக்கும் எஞ்சிய, ஒரு சில நாட்களே பழையதான, ஆய்வகக் கிண்ணத்தில் உண்டாக்கப்பட்ட கருமுளைகளிலிருந்து (எம்ப்ரியோக்கள்) தான் கரு குருத்தணுக்கள் தயாரிக்க படுகின்றன.

ஜ.பி.எஸ்/ஐபிஸ் – இன்ட்யூஸ்ட் ப்லுரிபோடென்ட் ஸ்டெம்) அல்லது

தூண்டப்பட்ட பன்திறன் குருத்து உயிரணுக்கள் என்றால் என்ன?

விஞ்ஞானிகளும் மருத்துவர்களும் “ஐபிஎஸ்” உயிரணுக்கள் எனப்படும் புது வகை குருத்தணுக்களை கண்டு உற்சாகமடைந்துள்ளனர்.

இதற்க்கு காரணம் ஐபிஎஸ் உயிரணுக்கள் ஏறக்குரய கரு குருத்தணுக்களின் அனைத்து பண்புகளையும் கொண்டவை,

ஆனால் எந்தக் கருவிலிருந்தும் எடுக்கப் படுவதில்லை. இதனால், ஐபிஎஸ் உயிரணுக்களை உபயோகிப்பதில் எந்த நெறிமுறை கவலைகளும் இல்லை.

கூடுதலாக, ஐபிஎஸ் உயிரணுக்கள் நோயாளியின் உடம்பின் குருத்தணுக்களிலிருந்து செய்யப்படுவதால்,

அத��� நோயாளிக்கு திரும்ப செலுத்தும் பொழுது அவர் உடம்பின் நோய் எதிர்ப்பு அமைப்பு ஐபீஸ் உயிரணுக்களை நிராகரிக்காமல் ஏற்றுக்கொள்கிறது. குருத்தணுக்கள் நிராகரிக்கப் படுவது குருத்தணு சிகச்சையில் ஒரு முக்கிய பிரச்சனையாகும். வருங்காலம் எப்படி இருக்கப்போகிறது.....?

குருத்தணுக்கள் சிகிச்சை எப்படி *மாற்ற போகிறது? இதன் தத்துவம் என்னவென்றால், நோயாளிகளுக்கு ●குருத்தணுக்களையோ அல்லது ●குருத்தணுக்களினால் உருவாக்கப்பட்ட முதிர்ந்த ●உயிரணுக்களையோ கொடுப்பதன் ●மூலம் குருத்தணுக்களின் நோயை குணப்படுத்தும் இயற்கை தன்மையை பயன்படுத்தலாம்● என்பதுதான்.

●உதாரணமாக, மாரடைப்பு ஏற்பட்ட நோயாளியின் இதயத்திற்கு ஏற்பட்ட சேதத்தை சரி செய்வதை சிகிச்சையின் நோக்கமாகக் கொண்டு குருத்தணுக்களை அளிக்கலாம்.

இயற்கையாக நம் அனைவர் உடலில் இருக்கும் குருத்தணுக்களின் காயம் சரிசெய்யும் ஆற்றல் குறைவே.

முதலில் கூறிய இதயம் உதாரணத்தையே எடுத்துக்கொண்டால், இதயத்தின் இயற்கையான குருத்தணுக்கள் மாரடைப்பினால் ஏற்பட்ட சேதத்தை சரி செய்வதில் சற்றே யோக்கியதையற்றதாக இருக்கின்றன. ஆனால், இலட்சக்கணக்கான குருத்தணுக்கள் செலுத்தப்பட்டால் அதைவிட மிக சக்திவாய்ந்ததாக இருக்கும்.

எனவே நோயாளிகளுக்கு குருத்தணுக்களை செலுத்துவதன் மூலம் நாம் உடலின் குணமடையும் தன்மையை, இயற்கையாக உடலில் இருக்கும் சிறிதளவு குருத்தணுக்களின் ஆற்றலை தாண்டி மிகவும் அதிகரிக்கிறோம்.

குருத்தணு சிகிச்சைகள் பரவலாக பயன்படுத்த படுவதற்கு முன் சில சவால்களை சந்திக்க வேண்டியிருக்கிறது.???...........???????????

இந்த சவால்கள் என்னவென்றால்,

●●●●●●●●●●●●●●●●குருத்தணுக்கள் புற்று நோய் கட்டியை உருவாக்கக்கூடியவை

மற்றும்

●●●●●குருத்தணுக்கள் உடலின் நோய் எதிர்ப்பு அமைப்பால் நிராகரிக்கப்படுகின்றன. எனினும்,

குருத்தணுக்கள் மருத்துவத்தை உருமாற்ற கூடியவை.

இன்னும்

வெறும் 10பத்து 20 இருபதே ஆண்டுகளில் நமக்கோ அல்லது நமக்கு தெரிந்தவர் யாருக்கோ குருத்தணுக்கள் அளிக்கப்பட்டிருக்கும். குருத்தணுக்கள் மக்கள் எதிர்கொள்ளும் முக்கிய நோய்களான

■புற்று நோய், ■ இதய நோய்கள், ■மூளை சம்மந்தப்பட்ட நோய்களான – ■பார்கின்சன் நோய், ■மல்டிபல் ■ஸ்க்லெரோசிஸ், ■பக்கவாதம், ■ஹண்டிங்டன் நோய், ■முதுகுத்தண்டு காயமென பலவற்றை ●■குணப்படுத்தும் என நம்பிக்கை அளிக்கிறது■

இப்போது கிடைக்கும் குருத்தணு சிகிச்சைகள் யாவை?

தற்போது, விஞ்ஞானிகளால் நிரூபிக்கப்பட்ட பாதுகாப்பான பயனுள்ள குருத்தணு சிகிச்சைகள் சிலவற்றே உள்ளன. எலும்பு மஜ்ஜை (ஆங்கிலம்: போன் மேரோ) மாற்று சிகிச்சை இதற்க்கோர் சிறந்த எடுத்துக்காட்டு.

பெரும்பாலும் இச்சிகிச்சைகள், விளையாட்டு வீரர்கள் போன்ற பிரபலங்கள் மேற்கொள்ளும் பொது ஊடகங்களின் கவனத்தை மிகவும் ஈர்க்கிறது.

பொதுவாக, விஞ்ஞானிகளும் மருத்துவர்களும் இத்தகைய சிகிச்சை உண்மையில் பயன் தருமா

என்றும் பாதுகாப்பானவையா என்றும் சொல்வதற்கில்லை என்று நோயாளிகளை எச்சரிக்கை சைய்கிறார்கள்.

நோயாளிகள் இத்தகைய சிகிச்சைகளால் இறந்தும் போயிருக்கின்றனர்.

குணப்படுத்த முடியாத நோயை எதிர்கொள்ளும்போது அனைத்து வாய்ப்புகளையும் கருதினாலும்,

மருத்துவர்கள்

நாங்கள் பரிந்துரைப்பது என்னவென்றால் நீங்கள் இந்த STEM CELLS இச்சிகிச்சைகளை கடைசி நிவாரனமாகவே கருதவேண்டும்,

குறிப்பு ■■■■■■●●■ ஸ்டெம் செல் ஆராய்ச்சி வரலாற்றில் முக்கிய கண்டுபிடிப்புகள்

இந்தத் துறையில் ஆரம்பகால சோதனைகளில் ஒன்று சர் ஜான் கார்டன் தனது Ph.D. 1962 இல். அவர் பிளாஸ்டுலா கட்டத்தில் வளரும் தவளைக் கருவின் கருவை அகற்றி, கருவை அகற்றிய முட்டைக் கலத்தில் அதை செலுத்தினார்.

பெரும்பாலான சந்தர்ப்பங்களில், முட்டை தவளை டாட்போல்களாக உருவாகலாம், வேறுபட்ட உயிரணுக்களின் கருக்கள் இன்னும் எந்த உயிரணுக்களாகவும் உருவாகும் திறனைக் கொண்டுள்ளன என்பதைக் காட்டுகிறது. இந்த ஆய்வு இனப்பெருக்க குளோனிங்கின் அடிப்படையை உருவாக்கியது,

இது டோலி, குளோன் செய்யப்பட்ட செம்மறி ஆடுகளை உருவாக்க வழிவகுத்தது.

மற்றொரு முக்கிய கண்டுபிடிப்பு 1981 இல் மவுஸ் பிளாஸ்டோசிஸ்ட்களிலிருந்து கரு ஸ்டெம் செல்களை வளர்ப்பது ஆகும். அதைத் தொடர்ந்து, கரு ஸ்டெம் செல்களும் மனித பிளாஸ்டோசிஸ்ட்களிலிருந்து வளர்க்கப்பட்டன.

ஷின்யா யமனகாவும் அவரது சகாக்களும் 24 டிரான்ஸ்கிரிப்ஷன் காரணிகளின் தொகுப்பை அறிமுகப்படுத்துவதன் மூலம் சோமாடிக் செல்களை ப்ளூரிபோடென்ட் ஸ்டெம் செல்களில் ���ூண்ட முடிந்தபோது ஒரு முக்கிய கண்டுபிடிப்பு செய்யப்பட்டது.

2012 ஆம் ஆண்டு சர் ஜான் குர்டனுடன் இணைந்து மருத்துவத்துக்கான நோபல் பரிசு அவருக்கு வழங்கப்பட்டது.

[dradityasharma-1]

Fertility Solutions: Male Infertility Treatment Breakthroughs Male infertility is a growing concern, affecting millions of men worldwide. However, recent advancements in medical science are providing new hope. This blog explores some of the latest breakthroughs in male infertility treatment, highlighting key solutions and care options available near you.

Understanding Male Infertility Male infertility refers to a man's inability to impregnate a fertile woman. The causes are diverse, ranging from hormonal imbalances, genetic factors, and lifestyle choices to physical problems like varicocele or blockages in the reproductive system. Identifying the root cause is crucial for effective treatment.

Breakthrough Treatments Hormonal Therapy Hormonal imbalances can significantly impact sperm production and quality. Recent advances in hormonal treatments are showing promising results. Therapies involving follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are helping men improve their fertility levels.

Assisted Reproductive Techniques (ART) ART methods, such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), have revolutionized male infertility treatment. These techniques allow direct handling of sperm and eggs, increasing the chances of successful conception.

Genetic Testing and Therapy With advancements in genetic testing, identifying genetic abnormalities that cause infertility is now possible. Gene therapy is a pioneering approach aimed at correcting these genetic issues, potentially restoring fertility in affected men.

Stem Cell Therapy Stem cell therapy is an emerging field with the potential to treat male infertility. Research is ongoing, but early studies suggest that stem cells can regenerate damaged tissues in the reproductive system, offering a novel treatment option.

Expert Care Options Near You Finding the right care is essential for addressing male infertility. For those in Lucknow, excellent options are available:

Best Endo Urology Care in Sector B, Lucknow Sector B in Lucknow boasts some of the best endo urology care facilities, offering state-of-the-art treatments for various urological issues, including male infertility.

Best Uro Oncology Care Near Me Uro oncology specialists in Lucknow provide comprehensive care for male infertility, especially when related to oncological conditions.

Kidney Transplant Near Me Kidney health is closely linked to overall reproductive health. Leading kidney transplant centers in Lucknow also provide integrated care for male infertility.

Best Female Urology Care with Dr. Aditya Sharma While primarily focused on female urology, Dr. Aditya Sharma’s clinic also offers excellent male infertility treatment options, ensuring comprehensive reproductive health care.

Best Pediatric Urology Care Pediatric urology care centers are crucial for addressing congenital issues that might affect future fertility. Early diagnosis and treatment can prevent long-term infertility.

Best General Urology Care Near Me General urology care centers in Lucknow provide a broad range of services, including diagnosis and treatment of male infertility, using the latest medical technologies.

Male Infertility Care Near Me Specialized male infertility clinics offer personalized treatment plans, focusing on the specific needs and conditions of each patient.

Urological Hospital Near Me Top urological hospitals in Lucknow provide comprehensive services, from diagnosis to advanced treatments for male infertility, ensuring the best possible outcomes.

Conclusion The landscape of male infertility treatment is rapidly evolving, with new breakthroughs offering renewed hope to many. By understanding the latest treatments and knowing where to find expert care, men facing infertility issues can take proactive steps towards achieving their dream of fatherhood. Whether you’re seeking the best endo urology care in Sector B, Lucknow, or looking for specialized male infertility care near you, numerous options are available to provide the support and treatment you need.

Dr Aditya Sharma MCh Urologist (Gold Medalist) Uro-oncology Kidney Transplant Robotic Surgeon

Address: Kanpur - Lucknow Rd, Sector B, Bargawan, LDA Colony, Lucknow, Uttar Pradesh 226012

Phone: 081300 14199

Website: https://dradityaurologist.com/

[drchiraggupta]

Treatment Options for Male Infertility: A Comprehensive Guide

Male infertility can be a challenging and distressing issue for many couples trying to conceive. Understanding the available treatment options is crucial for making informed decisions. This guide explores various treatment approaches, from lifestyle changes to advanced medical procedures, offering hope to those facing male infertility.

1. Lifestyle and Behavioral Changes

Before delving into medical treatments, consider lifestyle and behavioral changes that can significantly impact fertility:

- Healthy Diet: A balanced diet rich in antioxidants, vitamins, and minerals can improve sperm quality.

- Exercise: Regular physical activity can boost testosterone levels and improve overall health.

- Avoiding Toxins: Limiting exposure to environmental toxins, such as pesticides and heavy metals, is crucial.

- Reducing Stress: Stress can negatively affect sperm production. Practices like yoga, meditation, and counseling can help.

- Quitting Smoking and Limiting Alcohol: Both smoking and excessive alcohol consumption can impair sperm quality.

2. Medical Treatments

Several medical treatments are available to address specific causes of male infertility:

Medications

- Hormonal Treatments: Hormonal imbalances can be treated with medications to restore normal levels of testosterone and other hormones.

- Antibiotics: Infections in the reproductive tract can affect sperm production. Antibiotics can treat these infections.

- Antioxidants and Supplements: Supplements like Coenzyme Q10, Vitamin E, and zinc can improve sperm quality and motility.

Surgery

- Varicocele Repair: Varicocele, an enlargement of veins within the scrotum, can be corrected surgically to improve sperm count and quality.

- Vasovasostomy and Vasoepididymostomy: These procedures reverse vasectomies and clear obstructions in the reproductive tract.

- Testicular Sperm Extraction (TESE): This surgical procedure retrieves sperm directly from the testicles, often used in conjunction with in vitro fertilization (IVF).

3. Assisted Reproductive Technologies (ART)

ART offers advanced solutions for male infertility, particularly in severe cases:

Intrauterine Insemination (IUI)

IUI involves placing specially prepared sperm directly into the uterus during ovulation. This method can be effective for mild male infertility issues, such as low sperm motility.

In Vitro Fertilization (IVF)

IVF is a widely used ART technique where an egg is fertilized by sperm outside the body. The resulting embryo is then implanted into the uterus. IVF can be combined with other techniques, like Intracytoplasmic Sperm Injection (ICSI).

Intracytoplasmic Sperm Injection (ICSI)

ICSI is a specialized form of IVF where a single sperm is injected directly into an egg. This method is particularly useful for severe male infertility, such as low sperm count or poor motility.

4. Donor Sperm

For some couples, using donor sperm might be the best option. This involves insemination with sperm from a donor, which can be done through IUI or IVF. Donor sperm can be an effective solution for men with genetic disorders, azoospermia (complete absence of sperm), or other severe infertility issues.

5. Emerging Treatments and Research

Advancements in medical research continue to provide new hope for male infertility:

- Stem Cell Therapy: Researchers are exploring the potential of stem cells to regenerate sperm cells.

- Genetic Treatments: Identifying and correcting genetic mutations that cause infertility is a growing field of study.

- Artificial Intelligence: AI is being used to improve sperm selection and increase the success rates of ART procedures.

Conclusion

Male infertility can be addressed through a variety of treatments, from lifestyle changes and medications to advanced reproductive technologies. Consulting with a qualified andrologist or fertility specialist is essential to determine the most appropriate treatment plan for your specific condition. With the right approach, many men can overcome infertility challenges and achieve their dream of fatherhood.

[fairfield-research]

Regenerative Medicine Market - Global Growth, Share, Trends, Demand and Analysis Report Forecast 2031

In the ever-evolving landscape of healthcare, regenerative medicine (RM) stands out as a beacon of hope, offering multifaceted solutions to complex medical challenges. With chronic diseases proliferating at an alarming rate, RM is emerging not just as a treatment option but as a potential cure, challenging conventional long-term therapies. Stem cell therapy and nanotechnology are driving forces behind this paradigm shift, offering novel approaches to wound healing and disease management.

For more information: https://www.fairfieldmarketresearch.com/report/regenerative-medicine-market

Addressing Critical Healthcare Needs

The global market for regenerative medicine is propelled by the pressing demand for solutions to emergency trauma cases and degenerative diseases. Challenges in organ transplantation, such as organ shortages, further underscore the necessity for innovative therapies. Technological advancements in surgery and disease monitoring complement the expansion of the regenerative medicine market, ushering in a new era of medical interventions.

Robust Pipeline Signals Growth Potential

A robust pipeline of over 300 gene therapy and stem cell products in industrial development, along with 20% developed by academic and research institutions, heralds a promising outlook for market growth. With regulatory approvals from esteemed agencies like the FDA, EMA, PMDA, and MFDS, approximately 54 regenerative medicine products are already making strides in the market. Moreover, over 1000 ongoing clinical trials worldwide highlight the relentless pursuit of breakthrough treatments.

Resilience Amidst Global Challenges

Despite the unprecedented disruptions caused by the COVID-19 pandemic, the regenerative medicine sector has exhibited remarkable resilience. In the first half of 2020 alone, the sector raised $10.7 billion globally, surpassing the total amount raised in the preceding year. This steadfast investment influx underscores the unwavering commitment to advancing regenerative medicine research and development.

Navigating Market Access Challenges

While the potential of regenerative medicine is immense, challenges persist in terms of market access. The high costs of treatment and reimbursement complexities pose significant hurdles. Pricing variations across regions, coupled with evolving perspectives on the value of innovative therapies, necessitate nuanced approaches to market entry and affordability.

Asia's Untapped Potential

The underdeveloped clinical landscape of Asia presents a unique opportunity for stakeholders to establish a prominent presence. With North America and Europe leading the market, Asia's burgeoning biopharma needs and growing awareness of personalized medicine offer fertile ground for expansion. Strategic partnerships and investments in the region can unlock substantial growth avenues.

Diverse Market Dynamics

The regenerative medicine market is characterized by its diversity, with over 1000 small and medium-sized therapeutic developers actively contributing to its evolution. While big pharma giants adopt a cautious approach, focusing on proven concepts and strategic partnerships, smaller players dominate the landscape, driving innovation and competition.

Key Players Driving Innovation

A plethora of key players, including APAC BIOTECH, Anges, Avexis, Dendreon, and BioMarin, among others, are at the forefront of driving innovation in the global regenerative medicine market. Their collective efforts span gene therapy, stem cell research, and novel therapeutic interventions, shaping the future of healthcare.

About the Regenerative Medicine Market

The regenerative medicine market represents a dynamic ecosystem of research, development, and innovation, poised to revolutionize healthcare delivery. With a steadfast commitment to addressing unmet medical needs and advancing therapeutic interventions, stakeholders across the globe are driving the momentum toward a healthier, more resilient future.

[bhavanameti]

Asia-Pacific Plasma Therapy Market Expected to Reach $214 Million by 2030

Meticulous Research®, a leading global market research company, published a research report titled, ‘Asia-Pacific Plasma Therapy Market, By Type (Pure Platelet-rich Plasma, Platelet-rich Fibrin), Application (Orthopedics, Dermatology, Cosmetology, Rheumatology, Ophthalmology, Stomatology), End User (Hospitals & Clinics, Research Institutes) - Forecast to 2030’.

In the latest Meticulous Research® report, the Asia-Pacific Plasma Therapy Market is forecasted to reach $214 million by 2030, with a notable CAGR of 13.4% from 2023 to 2030. This growth is propelled by increased healthcare spending, a growing elderly population, and a notable rise in accidents across the region. Additionally, advocacy through conferences for Platelet-Rich Plasma (PRP) adoption and ongoing research activities drive market expansion. Despite stringent regulations posing challenges, the increasing adoption of PRP treatments and advancements in healthcare infrastructure offer promising growth prospects.

Key Players:

Leading players in the Asia-Pacific plasma therapy market include Arthrex, Inc., DePuy Synthes, Inc., Global Stem Cells Group, Inc., Terumo Corporation, Regen Lab SA, Stryker Corporation, Zimmer Biomet Holdings, Inc., Exactech Inc., Beijing Manson Technology Co., Ltd., Alocuro, Takeda Pharmaceutical Company Limited, Grifols, S.A., Octapharma AG, and CSL Limited.

Future Outlook:

Segmented by type, application, end-user, and country, the market is expected to be dominated by Pure PRP in 2023 due to its efficacy as a point-of-care therapy. The dermatology & cosmetology segment is projected to witness the highest CAGR, driven by increasing incidences of skin and hair-related conditions. Hospitals & clinics are likely to hold the largest market share in 2023, leveraging PRP therapy for pain management, regenerative medicine, and cosmetic enhancements.

Geographic Review:

Covering major countries such as China, Japan, India, South Korea, Australia, Singapore, and the Rest of Asia-Pacific, Japan is anticipated to lead the market in 2023. This is attributed to growing awareness of PRP therapy and increasing infertility issues, with physicians employing PRP in fertility treatments to aid market growth."

Download Sample Report Here @ https://www.meticulousresearch.com/download-sample-report/cp_id=5556

Key Questions Answered in the Report:

Which market segments exhibit high growth potential?

What are the historical and forecasted market trends?

What are the major drivers, restraints, challenges, and opportunities?

Who are the key players in the market?

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