#sociogenomics
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Why Rallies Work
Metastatic Tribalism that forms our Populist Extremes Metastatic tribalism can be seen as the conduit for social transformation that takes place through the social genetics of the tribe. Social genetics, more succinctly sociogenomics is the exposure generated social interaction that changes the macro epigenome of the tribe. This is clearly illustrated in the dramatic frenzied shift that…
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Postodoctoral researcher in genoeconomics/sociogenomics Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki Come join us in #FIMM as a #Postodoctoral researcher in genoeconomics/sociogenomics See the full job description on jobRxiv: https://jobrxiv.org/job/institute-for-molecular-medicine-finland-fimm-hilife-university-of-helsinki-27778-postodoctoral-researcher-in-genoeconomics-sociogenomics/?feed_id=49353 #ScienceJobs #hiring #research Helsinki #Finland #PostdoctoralFellow
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Daniel W. Belsky, Benjamin W. Domingue, Robbee Wedow, Louise Arseneault, Jason D. Boardman, Avshalom Caspi, Dalton Conley, Jason M. Fletcher, Jeremy Freese, Pamela Herd, Terrie E. Moffitt, Richie Poulton, Kamil Sicinski, Jasmin Wertz, and Kathleen Mullan Harris
Significance
Genome-wide association study (GWAS) discoveries about educational attainment have raised questions about the meaning of the genetics of success. These discoveries could offer clues about biological mechanisms or, because children inherit genetics and social class from parents, education-linked genetics could be spurious correlates of socially transmitted advantages. To distinguish between these hypotheses, we studied social mobility in five cohorts from three countries. We found that people with more education-linked genetics were more successful compared with parents and siblings. We also found mothers’ education-linked genetics predicted their children’s attainment over and above the children’s own genetics, indicating an environmentally mediated genetic effect. Findings reject pure social-transmission explanations of education GWAS discoveries. Instead, genetics influences attainment directly through social mobility and indirectly through family environments.
(Emphasis added)
#pnas#national academy of sciences#kathleen mullan harris#genetics#social mobility#heritability#heredity#genome-wide association study#social class#sociogenomics#polygenic score#read the whole thing#biology#human genetics
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https://en.m.wikipedia.org/wiki/Sociogenomics
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Lies, damned lies, and GWAS
Lies, damned lies, and GWAS
Well, I provoked another kerfuffle in the pages of Nature. And it’s a troubling one, because it suggests a widening culture gap between the sciences and humanities—a gap I’ve spent a quarter-century-and-counting trying to bridge.
The piece in question is my review of Robert Plomin’s new book, Blueprint. I want here to give some context and fuller explanation for that piece, without the editorial…
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My identity couldn’t be broken down into halves, and there was no way that my many life-altering experiences could be read from my cellular material. In fact, if we were taking a long historical view, there would be so many places my ancestors had stopped along the way that everything about my heritage could be seen as mixed. The idea that my mom and dad and their families were genetically distinct to their core, and of a different race than me, was simply ludicrous.
Read how Dr. Catherine Bliss found her way into sociogenomics (and what that even is) on The Offing!
#Sociogenomics#Dr. Catherine Bliss#The Offing#Back of The Envelope#BOTE#race#ethnicity#genomics#science#determinism#genetics#sociology#Social By Nature
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Fwd: Graduate position: MNHN_Paris.SocialEvolutionInsects
Begin forwarded message: > From: [email protected] > Subject: Graduate position: MNHN_Paris.SocialEvolutionInsects > Date: 12 March 2020 at 06:29:55 GMT > To: [email protected] > > > Sociality and convergent evolution: insights from ecomorphology and > transcriptomics in cockroaches > > The Museum national d'Histoire naturelle in Paris invites applications > for a 3-year PhD position in evolutionary biology. The PhD project will > be conducted under the supervision of Frédéric Legendre and Philippe > Grandcolas within the Institut de Systématique, Evolution, Biodiversité > (http://isyeb.mnhn.fr). > > Description > Despite progresses made in particular through kinship selection, > understanding the circumstances of the emergence of integrated > social systems remains a major challenge. In diploid organisms, > unlike haplo-diploid organisms, kinship selection is, however, > not the primary evolutionary cause. Ecological or morphological > factors may have played a major role in the origin of sociality, but > their relative importance remains suggested rather than quantified, > without any formal phylogenetic test. This project aims to study, in a > comparative framework, the influence of ecomorphological factors on the > evolution of eusociality in the Blattodea (cockroaches and termites), > a group of diploid insects with several subsocial convergent lineages > and a single eusocial lineage. These tests will be conducted in the > shift-in-dependent-care hypothesis framework, which emphasizes the > importance of a wood diet and a subsocial behaviour. In parallel, > transcriptomic analyses will be carried out on four targeted species, > in order to assess the differential gene expression between wood-eating > (or not) and subsocial (or not) species. Those transcriptomic data will > also be used to assemble the genomic data acquired elsewhere (out of the > scope of the PhD project) in the framework of the ANR PRCI SOCIOGENOMICS > (PIs: F. Legendre and E. Bornberg-Bauer; 2020-2024). The PhD student will > thus work in collaboration with our partner, specialized in comparative > genomics of insects. > > Methods > The ecomorphology of the cockroach species and their social behaviours > will be defined on the basis of literature and natural history > collections. Several morphological features will be characterized: general > shape, shape and ornamentation of the pronotum, leg ornamentation, shape > of the mandibles, eye size, presence and length of wings. Parental > behaviours will be identified from a pre-established list of 11 > behaviours. Due to the broad comparative framework, an initial focus will > be made on four essential lineages (and their sister-groups) and then > progressively extended to other lineages, starting with those present > in our 2015 phylogeny, which will serve as a basis for comparative > phylogenetic analyses. For the latter, state-of-the-art methods will > be used (e.g. phylogenetic path analysis, morphospace, ancestral state > modeling). > > Skills required > - Master degree in evolution, systematics, biodiversity or any project- > related discipline. > - Established knowledge in phylogenetics and modern comparative methods > (including skills in R). > - Ability to work in an international collaboration. > - Knowledge in comparative anatomy (of insects). > - Expertise in transcriptomic analysis or in the evolution of sociality > would be an asset, as would a naturalist background. > > Application submission > Applications must be submitted before the 5th of April 2020. The PhD will > begin between May and October 2020. Please send your applications to both > supervisors: detailed resume, motivation letter, grades (including M2 if > possible), contact details of your current and previous surpervisors. Do > not hesitate to contact us before sending your application if you want > to talk about the project. > > Contacts > [email protected] > [email protected] > > Frédéric Legendre > Associate Professor, HDR > Curator of Dictyoptera > Institut Systématique, Evolution, Biodiversité (ISYEB) > Muséum national d'Histoire naturelle > UMR 7205, MNHN, CNRS, Sorbonne Université, EPHE > CP50, 45 rue Buffon > 75231 Paris Cedex 05, FRANCE > tel: +33 1 40 79 81 26 > Fax: +33 1 40 79 56 79 > Email: [email protected] > > Frédéric LEGENDRE > via IFTTT
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"Then there are the dystopian outcomes. Prospective employers could ask you to submit your genetic income score as part of a job application. Health and life insurers could use it to calculate your premiums. Social programs might use it as disqualifying criteria for receiving benefits. Apps like the ones that prevent you from accidentally dating a relative could help you pair up with those genetically inclined toward prosperity. IVF clinics could incorporate it into their genetic screening procedures so parents can choose the highest-earning embryos in addition to the healthiest ones. For every opening to use such information to create a more fair and just society, there exist in equal measure opportunities to weaponize it to exacerbate existing inequalities or perpetuate new ones.
...'We’ve been shying away from looking at income for a very long time, for a number of reasons,' says Philipp Koellinger, an economist at the Vrije Universiteit in Amsterdam, where he studies the genetics of behavior. Looking at the molecular architecture of money-making has a lot of potential to be misinterpreted or abused, he says. Especially by fringe groups who might latch on to sociogenomic research as support for racist notions of a hierarchy of human worth. Despite its new name and new software packages, the emerging field of sociogenomics will forever be entangled with the long, dark, history of the statistical tools that serve as its foundation—tools invented by some of the grandfathers of American eugenics. (For more on this, I’d suggest Carl Zimmer’s excellent book on the science of inheritance.)"
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✖ ━ What’s something you’re very curious about?
This is probably an obvious one, but definitely genetics. I don’t talk about my research as much as my characters on this blog, but the book I’m working on is FILLED with genetic research. I couldn’t fit it all in there without it sounding too much like a textbook and not enough like an exciting sci-fi, but I’m fascinated with things like genome synthesis and CRISPR/Cas9 and sociogenomics. I love learning new things and I love it even more when those new things can be incorporated into my story.
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(summary/op ed) A lot of science has been created by people with access to resources and to mainstream narratives, and some of the dominant thought in the history of those sciences - sociogenomics in this example - have been used to promote racist beliefs. We shouldn’t cancel sociogenomics because of this, but at the same time I can’t think of ways in which research in this field would be beneficial, unless it is to explicitly disprove genomic determinancy. The least a researcher can do is to add a blog post to describe the limits of their research.
Add: and to explicitly do research in places of the world where there is no data and to empower the people there to also be researchers in the field
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How Hidden Social Contexts Influence Your Genetics - Facts So Romantic
blog tumbling : Educational attainment has some qualitatively unique features that we’re going to have to be sensitive to when we attempt to study the genetics of it.Photograph by Joey Yee / Flickr What if a wound of yours, a pierced ear, say, healed at a different rate depending on who was around you? A 2017 study explored this question, albeit with mice. Researchers paired mice together, punching holes in their ears, and tracked the rate of recovery. They found that the genome of a cagemate affected how fast their ears healed. Benjamin Domingue, an assistant professor at the Stanford Graduate School of Education who studies sociogenomics, was fascinated by what the researchers called an “indirect” or “social” genetic effect. He wanted to see if similar things were going on in humans. Through the National Longitudinal Study of Adolescent to Adult Health, a sample of 15,000 Americans who were between 7th and 12th grade in 1994-95, and which is now on its fifth wave of data collection, Domingue and his colleagues were able to test for the influence of social genetic effects on educational attainment and relationships like friendship. Previous studies, for instance, have demonstrated that friends… Read More… http://dlvr.it/QG833D @robinravi
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less than i greater than Social by Nature: The Promise and Peril of Sociogenomics less than /i greater than - Catherine Bliss
Sociogenomics has rapidly become one of the trendiest sciences of the new millennium. Practitioners view human nature and life outcomes as the result of genetic and social factors. In Social by Nature, Catherine Bliss recognizes the promise of this i https://www.environmentguru.com/pages/elements/element.aspx?utm_source=dlvr.it&utm_medium=tumblr&id=5988371
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Postodoctoral researcher in genoeconomics/sociogenomics Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki Come join us in #FIMM as a #Postodoctoral researcher in genoeconomics/sociogenomics See the full job description on jobRxiv: https://jobrxiv.org/job/institute-for-molecular-medicine-finland-fimm-hilife-university-of-helsinki-27778-postodoctoral-researcher-in-genoeconomics-sociogenomics/?feed_id=49241 #ScienceJobs #hiring #research Helsinki #Finland #PostdoctoralFellow
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Invited Commentary: Integrating Genomics and Social Epidemiology—Analysis of Late-Life Low Socioeconomic Status and the Conserved Transcriptional Response to Adversity
Abstract
Socially disadvantaged children face increased morbidity and mortality as they age. Understanding mechanisms through which social disadvantage becomes biologically embedded and devising measurements that can track this embedding are critical priorities for research to address social gradients in health. The analysis by Levine et al. (Am J Epidemiol. 2017;186(5):503–509) of genome-wide gene expression in a subsample of US Health and Retirement Study participants suggests important new directions for the field. Specifically, findings suggest promise in integrating gene expression data into population studies and provide further evidence for the conserved transcriptional response to adversity as a marker of biological embedding of social disadvantage. The study also highlights methodological issues related to the analysis of gene expression data and social gradients in health and a need to examine the conserved transcriptional response to adversity alongside other proposed measurements of biological embedding. Looking to the future, advances in genome science are opening new opportunities for sociogenomic epidemiology. http://ift.tt/2iYxVf5
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