#sesquiterpene lactones

[invoke-parlay]

I’m harvesting and drying my 100% organic, grown from seed Yarrow today. Let me know via DMs if you’d like some ☺️

Yarrow // Achillea millefolium

Parts Used: aerial portions, including flower and leaves.

Family: Asteraceae

Other Names: allheal, angel flower, bad man’s plaything, bloodwort, cammock, carpenter’s weed, devil’s mustard, devil’s nettle, devil’s plaything, dog daisy, gordaldo, gordoloba, green arrow, herbe militaris, hierba de las cortadura, knight’s milfoil, milfoil, nosebleed plant, old man’s mustard, old man’s pepper, sanguinary, soldier’s woundwort, squirrel’s taile, stanchgrass, staunchweed, thousand weed, thousand-leaf, thousand-seal, woundwort, yarroway

Native to Europe, Asia, and North America, yarrow is found in temperate regions all over the world.

Actions and Properties:

alterative, anti-fungal, anti-inflammatory, anti-pyretic, antiallergenic, antibacterial, antiseptic, antispasmodic, appetite stimulant, aromatic, astringent, bitter, carminative, circulatory stimulant, diaphoretic, digestant, diuretic, emmenagogue, expectorant, hemostatic, styptic, tonic, vulnerary

Constituents:

Yarrow is rich in essential oil and tannins. Yarrow contains 0.3% to 1.4% volatile oils (azulenes, eugenol, caaryophyllene, humulene, limonene, sabinene, thujone, borneol, and camphor), resin, sesquiterpene lactones, 3-4% tannins, flavonoids (including luteolin, apigenin, kaempferol, rutin, and quercitrin), alkaloids (achilletin, betonicine, stachydrine, trigonelline), alkamides, asparagin, aconitic and isovalerianic acids, selenium, beta-cerotene, proteins, sugars, phenolic acids, and coumarins. Its anti-inflammatory and anti-allergy effects may be associated with the constituent chamazulene. The alkaloid fraction of yarrow has shown evidence of hypotensive effects as well as antipyretic effects. Volatile oils in yarrow may have CNS depressent activity. The constituent Achilleine, an alkaloid, might decrease clotting time.

Yarrow is toxic to horses, dogs and cats

All my info is from this lovely website :)

[collectivecartomancy]

Dandelion & Diabetes

Hey Everybody! Here’s my final for Rootwork Herbals People’s Medicine School.

Once it’s accepted, I’ll be a real, live community herbalist and I’m so excited! 🥹 🥹 🥹

Please feel free to put any questions or concerns in the comments, or email me directly at cyreejarelle@collectivecartomancy.com.

Thanks for bearing witness to this wonderful experience :)

As ever, wishing you well,

Cyree Jarelle

Dandelion/Taraxacum officinale: Overview

Dandelion is a perennial flowering herb that grows from a long taproot.

Its name has been associated with the Persian tark hashgun, which means wild endive.

Rodale's Illustrated Encyclopedia of Herbs, suggests an origin in the Greek taraxos is more likely. Taraxos is a Greek word for "disorder" and as Rodale's writes, akos means remedy.

This is the relationship that humans have kept with Dandelion. It's abundant, nigh unkillable, and easy to identify. The designation officinale refers to Dandelion's inclusion in early apothecaries. Its earliest written virtues are in the Tang Bencao, written during the Tang dynasty.

Dandelion has a history in Europe and the United States, where it's used to treat diseases of the liver and GI tract.

Dandelion is a bitter stimulant with diuretic and laxative properties.

Unlike other diuretics, dandelion does its work without depleting potassium in the body. This is due to the potassium richness of dandelion itself.

Type 2 Diabetes & Dandelion

Diabetes is an endocrine disorder. It primarily affects the pancreas, an organ in the digestive system found in the upper abdomen. The pancreas produces the hormones to control blood sugar, including insulin, glucagon, peptides, and somatostatin. It also makes enzymes essential to the digestion of food.

Diabetes has many risk factors and symptoms, but all types of diabetes involve insulin.

Type 2 Diabetes is characterized by the pancreas no longer making enough insulin to process sugar in one's diet. This can cause disruptions throughout the body, with notable impacts on the heart, liver, and eyes.

Wirngo et. al published "The Physiological Effects of Dandelion (Taraxacum Officinale) in Type 2 Diabetes" in 2016. There they attribute Dandelion's anti-diabetic properties to its "bioactive chemical components." These include "chicoric acid, taraxasterol (TS), chlorogenic acid, and sesquiterpene lactones," they write.

Wirngo et. al. assert that herbal medicine and other traditional medicines have "demonstrated potential to alleviate diabetic symptoms, enable recovery, and improve health." Dandelion does this by fighting inflammation, which can harm tissues throughout the body.

Dandelion's bitter taste is due to "sesquiterpene lactones." These include "taraxacolide, dihydro-lactucin, ixerin D, taraxinic acids, phenyl propanoids, and ainslioside." These constituents have have anti-inflammatory properties. Dandelion's foundational action as a bitter facilitates proper digestion.

Dandelion is so rich with CGA that it is a viable alternative to proprietary antioxidants. CGA itself is anti-diabetic, and it's best in it's natural form according to Wirngo. It also contains high levels of CRA, which combined with other inulin rich herbs such as Burdock Root and Chicory, helps people metabolize fats better.

When we metabolize fats better, it can decrease our cholesterol. CRA can also make us produce more bile, which breaks down fat and helps flush waste from our livers. CRA is also a strong anti-diabetic.

Bile breaks fat down into fatty acids. Fatty acids provide our bodies with a source of energy. Their presence also impacts the body's response to hormones, including insulin.

In fact, the way our bodies work with fatty acids can be very important for individuals with diabetes. This is because many people with type 2 diabetes have insulin resistance. Their bodies may not be able to store fatty acid as easily.

As a result, these fatty acids may deposit in the liver. This can cause Non-Alcoholic Fatty Liver disease, which allopathic doctors cannot treat well. They generally just tell patients to lose weight and lower their cholesterol. (Ask me how I know lol.)

According to Sears and Perry, "90 % of obese type-2 diabetic patients have NAFLD." Even people without diabetes are likely to have NAFLD though, due to poor nutritional options in the United States. They go on to note that researchers expect 50% of Americans to have NAFLD by 2030.

Dandelion is a beautiful medicine for people in this position because it supports the liver and helps lower cholesterol. It does this while also stimulating the metabolism, and aiding digestion. It's highly anti-oxidant and anti-carcinogenic. Dandelion root is also among the vegetables highest in beta-carotene. Beta-carotene becomes Vitamin A in the body.

Vitamin A improves eye function, helps the immune system and keeps our skin healthy. This is essential for people with diabetes, because they are prone to complications with all three, many of them serious.

Dandelion has the potential to ease symptoms of diabetes at low cost.

Specifically, it can lower the cholesterol, which is a major risk factor for the heart and liver complications of type 2 diabetes. This is essential because 80% of people with diabetes live in countries without high incomes.

As Chen et. al report in their article "Income-related inequalities in diagnosed diabetes prevalence among US adults, 2001−2018" the " burden of diabetes falls disproportionately on low-income populations."

In the United States, the people experiencing the strongest correlation between poverty and diabetes are Black and Latina women between the ages of 45-65.

These are the people who have the most to gain from dandelion medicine. It's free in most cases, can be cultivated even in small spaces, and it's cheap. It's identifiable even by children, and abundant nearly everywhere.

Dandelion reduces blood sugar through its caffeic, chicoric, and chlorogenic acid components. It also "effects glucose uptake directly and indirectly" through its "alkaloids, glycosides, amino acids, terpenoids, inorganic ions, steroids, carbohydrates, and galactomannan gum" components.

Importantly, Dandelion has extremely low toxicity.

Dandelion Vinegar

Many diabetics avoid alcohol. If you're not into alcohol, try this vinegar!

Ingredients:

- Fresh dandelion tops

- Fresh dandelion leaves

- Dried dandelion roots

- Apple Cider Vinegar (with the mother, if you can get your hands on some)

Directions

1. Clean a glass jar of your choice

2. Sterilize the jar with boiling water.

3. Let the jar dry

4. Wash your fresh ingredients so that they are completely free of dirt and bugs.

5. Grind all ingredients down as fine as you can using a clean coffee grinder, clean blender, or a mortar and pestle.

6. Fill cleaned and sterilized jar up halfway with Dandelion parts.

7. Cover Dandelion parts with vinegar, then fill jar up to 1/2-3/4inch from the top with vinegar.

8. Stir and release any air bubbles

9. Top with a plastic cap. If you have no plastic caps, use parchment paper between the metal of the jar top and the rim of the glass jar.

Works Cited

The Role and Anatomy of the Pancreas. Animated Pancreas Patient. Youtube. September 6, 2013. Accessed January 26, 2024. 

Article Source: Income-related inequalities in diagnosed diabetes prevalence among US adults, 2001−2018

Chen Y, Zhou X, Bullard KM, Zhang P, Imperatore G, et al. (2023) Income-related inequalities in diagnosed diabetes prevalence among US adults, 2001−2018. PLOS ONE 18(4): e0283450. https://doi.org/10.1371/journal.pone.0283450

Choi UK, Lee OH, Yim JH, Cho CW, Rhee YK, Lim SI, Kim YC. Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. Int J Mol Sci. 2010 Jan 6;11(1):67-78. doi: 10.3390/ijms11010067. PMID: 20162002; PMCID: PMC2820990.

Fan M, Zhang X, Song H, Zhang Y. Dandelion (Taraxacum Genus): A Review of Chemical Constituents and Pharmacological Effects. Molecules. 2023 Jun 27;28(13):5022. doi: 10.3390/molecules28135022. PMID: 37446683; PMCID: PMC10343869.

Gamboa-Gómez CI, Rocha-Guzmán NE, Gallegos-Infante JA, Moreno-Jiménez MR, Vázquez-Cabral BD, González-Laredo RF. Plants with potential use on obesity and its complications. EXCLI J. 2015 Jul 9;14:809-31. doi: 10.17179/excli2015-186. PMID: 26869866; PMCID: PMC4746997.

Kania-Dobrowolska M, Baraniak J. Dandelion (Taraxacum officinale L.) as a Source of Biologically Active Compounds Supporting the Therapy of Co-Existing Diseases in Metabolic Syndrome. Foods. 2022 Sep 15;11(18):2858. doi: 10.3390/foods11182858. PMID: 36140985; PMCID: PMC9498421.

Li J, Luo J, Chai Y, Guo Y, Tianzhi Y, Bao Y. Hypoglycemic effect of Taraxacum officinale root extract and its synergism with Radix Astragali extract. Food Sci Nutr. 2021 Feb 26;9(4):2075-2085. doi: 10.1002/fsn3.2176. PMID: 33841825; PMCID: PMC8020951.

Li Y, Chen Y, Sun-Waterhouse D. The potential of dandelion in the fight against gastrointestinal diseases: A review. J Ethnopharmacol. 2022 Jul 15;293:115272. doi: 10.1016/j.jep.2022.115272. Epub 2022 Apr 8. PMID: 35405251.

Pfingstgraf IO, Taulescu M, Pop RM, Orăsan R, Vlase L, Uifalean A, Todea D, Alexescu T, Toma C, Pârvu AE. Protective Effects of Taraxacum officinale L. (Dandelion) Root Extract in Experimental Acute on Chronic Liver Failure. Antioxidants (Basel). 2021 Mar 24;10(4):504. doi: 10.3390/antiox10040504. PMID: 33804908; PMCID: PMC8063808.

Sears B, Perry M. The role of fatty acids in insulin resistance. Lipids Health Dis. 2015 Sep 29;14:121. doi: 10.1186/s12944-015-0123-1. PMID: 26415887; PMCID: PMC4587882.

Seo SW, Koo HN, An HJ, Kwon KB, Lim BC, Seo EA, Ryu DG, Moon G, Kim HY, Kim HM, Hong SH. Taraxacum officinale protects against cholecystokinin-induced acute pancreatitis in rats. World J Gastroenterol. 2005 Jan 28;11(4):597-9. doi: 10.3748/wjg.v11.i4.597. PMID: 15641154; PMCID: PMC4250819.

Suo C, Polanski K, Dann E, Lindeboom RGH, Vilarrasa-Blasi R, Vento-Tormo R, Haniffa M, Meyer KB, Dratva LM, Tuong ZK, Clatworthy MR, Teichmann SA. Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins. Nat Biotechnol. 2024 Jan;42(1):40-51. doi: 10.1038/s41587-023-01734-7. Epub 2023 Apr 13. PMID: 37055623; PMCID: PMC10791579.

Wirngo FE, Lambert MN, Jeppesen PB. The Physiological Effects of Dandelion (Taraxacum Officinale) in Type 2 Diabetes. Rev Diabet Stud. 2016 Summer-Fall;13(2-3):113-131. doi: 10.1900/RDS.2016.13.113. Epub 2016 Aug 10. PMID: 28012278; PMCID: PMC5553762.

[recentlyheardcom]

Many Benefits Essential Oils for Hair You Get by Using Them

Author Julia Gusmano Published December 27, 2016 Word count 480 Essential oils can be used in different ways to help promote physical and emotional health as well as well-being. The chemistry of essential oils is complex; for example, an petroleum contains an elaborate mixture of aromatic constituents such as alcohols, aldehydes, esters, ketones, lactones, phenols, terpenes and sesquiterpenes…

[tips-from-john]

Is Balmorex Pro Safe? BALMOREX PRO REVIEWS – Balmorex Pro Reviews – Balmorex Pro

Here's a detailed product review of Balmorex Pro, structured in a format similar to the models previously provided, complete with emojis for enhanced readability and engagement:

#BalmorexPro #BalmorexProReviews #BalmorexProReview

Does Balmorex Pro really work? What is Balmorex Pro? How to Use Balmorex Pro?

We answer these questions in this comprehensive review of Balmorex Pro. Discover everything you need to know about this advanced muscle, back, and joint health solution.

🤔 What Is Balmorex Pro?

Many people still ask: what is Balmorex Pro?

Balmorex Pro is a revolutionary 27-in-1 formula that provides a comprehensive solution to maintain muscle, back, and joint health. This supplement is meticulously developed to offer total assistance, ensuring long-lasting benefits and supporting the body's overall health in a revolutionary way.

✅ How Does Balmorex Pro Work?

Balmorex Pro is designed to:

Promote optimal blood circulation and combat nerve pain.

Reach inflamed tissues to facilitate relaxation and provide relief from joint pain.

Increase collagen levels to support skin health and improve the proportions of synovial fluid in the joints.

This comprehensive solution is crafted with a unique blend of herbal and organic compounds, providing sustained benefits and relief from various types of bodily discomfort.

❤️ Balmorex Pro Ingredients

Balmorex Pro’s formula includes a powerful combination of natural ingredients:

MSM (Methylsulfonylmethane): A natural compound that is rich in sulfur.

Arnica Oil: Contains sesquiterpene lactones, flavonoids, and phenolic acids.

Hemp Seed Oil: A source of essential fatty acids, vitamins, minerals, and antioxidants.

Indian Incense (Boswellia serrata): Contains boswellic acids that help relieve joint pain and inflammation.

Aloe Vera: Known for its soothing properties and skin health benefits.

Epsom Salt (Magnesium Sulfate): Helps relax muscles and assist in detoxification.

Shea Butter: Rich in vitamins, fatty acids, and antioxidants.

Ginger Root: Contains compounds with anti-inflammatory effects.

📌 What are the Benefits of Using Balmorex Pro?

Improved joint health and mobility.

Reduced inflammation and nerve pain.

Enhanced skin hydration and health.

✳️ Special Offer

Order 6 or 3 pots of Balmorex Pro and receive 2 FREE e-books:

"Shortcut to Wellbeing" - Hack your way to more energy, focus, and performance.

"Upgraded Immunity" - Learn how to strengthen your immune system with expert recommendations.

FAQs

Are there any side effects of using Balmorex Pro?

No, Balmorex Pro is made from 100% natural ingredients and is designed to be safe with no known harmful side effects.

How much does Balmorex Pro cost?

Balmorex Pro is available in different pricing options to suit your needs. Check the official website for current pricing.

Does Balmorex Pro come with a guarantee?

Yes, Balmorex Pro comes with a satisfaction guarantee. If you are not satisfied with the results, you can return the product within a specified period for a full refund.

That concludes the Balmorex Pro Review.

Now you're informed about the functionality of Balmorex Pro, its recommended usage, and where to secure genuine Balmorex Pro.

I trust you found this review informative and look forward to connecting with you again soon!

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This is a Balmorex Pro Review. I hope you enjoyed this honest review.

Now you know how Balmorex Pro works and how to use it.

The post Balmorex Pro Reviews was first published on Flamengo Online.

[indusaroha]

Edible Mushrooms: A Comprehensive Review on Bioactive Compounds with Health Benefits and Processing Aspects

Mushrooms are well-known functional foods due to the presence of a huge quantity of nutraceutical components. These are well recognized for their nutritional importance such as high protein, low fat, and low energy contents. These are rich in minerals such as iron, phosphorus, as well as in vitamins like riboflavin, thiamine, ergosterol, niacin, and ascorbic acid. They also contain bioactive constituents like secondary metabolites (terpenoids, acids, alkaloids, sesquiterpenes, polyphenolic compounds, lactones, sterols, nucleotide analogues, vitamins, and metal chelating agents) and polysaccharides chiefly β-glucans and glycoproteins. Due to the occurrence of biologically active substances, mushrooms can serve as hepatoprotective, immune-potentiating, anti-cancer, anti-viral, and hypocholesterolemic agents. They have great potential to prevent cardiovascular diseases due to their low fat and high fiber contents, as well as being foremost sources of natural antioxidants useful in reducing oxidative damages. However, mushrooms remained underutilized, despite their wide nutritional and bioactive potential. Novel green techniques are being explored for the extraction of bioactive components from edible mushrooms. The current review is intended to deliberate the nutraceutical potential of mushrooms, therapeutic properties, bioactive compounds, health benefits, and processing aspects of edible mushrooms for maintenance, and promotion of a healthy lifestyle.

[anantam-ayurveda]

Kushta (Saussurea lappa): Health Benefits & How to Use

In the world of herbal medicine, few plants hold the same level of reverence and significance as Kushta, scientifically known as Saussurea lappa. This extraordinary herb, deeply rooted in the principles of Ayurveda, boasts a rich history and a plethora of health benefits. In this comprehensive guide, we delve into the various aspects of Kushta, from its chemical composition and qualities according to Ayurveda to its influence on Doshas and how to incorporate it into your daily life.

What is Kushta?

Kushta, scientifically known as Saussurea lappa, is a perennial herb belonging to the Asteraceae family. Native to the Himalayan regions of India, Pakistan, and Afghanistan, this herb is highly regarded in Ayurvedic medicine. It exhibits a combination of tastes, including bitter (tikta), pungent (katu), and sweet (madhur), and qualities like lightness (laghu) and dryness (ruksha).

The Chemical Composition and Useful Parts of Kushta

The potency of Kushta lies in its chemical composition. It contains essential oils, resin, tannins, and various phytochemicals that contribute to its medicinal value. The root of the Kushta plant is the primary part used for therapeutic purposes. Its active compounds include sesquiterpene lactones, which are known for their anti-inflammatory and immune-boosting properties.

Qualities of Kushta According to Ayurveda

Rasa (Taste): Kushta possesses a unique combination of tastes, including Tikta (bitter), Katu (pungent), and Madhur (sweet). This diverse taste profile imparts a distinctive and balanced flavor to Kushta.

Guna (Quality): Kushta's qualities encompass lightness (laghu) and dryness (ruksha). These attributes align perfectly with its traditional use in Ayurveda, where it serves as a remedy for various conditions, benefitting from its light and dry nature.

Virya (Potency): Kushta maintains a potent heating quality (ushna virya), making it a valuable herb for kindling the digestive fire (Agni). This heating potency contributes to its effectiveness in improving metabolism and aiding in the digestion of food.

Vipaka (Post-Digestive Effect): After digestion, Kushta exhibits a post-digestive effect that includes the tastes Tikta (bitter), Katu (pungent), and Madhur (sweet).

read more

[lalitrajsingh]

Sonchus oleraceus

Remedy for Vitiligo, Hepatitis & Rheumatism

Sonchus_oleraceus Cure_Vitiligo_Hepatitis_Anxiolytic_Rheumatism Herbaceous wild medicinal plant of #Asteraceae family identified as #Sonchus_oleraceus (#Milk weed). It contains #sesquiterpene lactones (#eudesmanolides, #guaianolide), vitamins-A, D, E, #apigenin & #proanthocyanidins. It cures #hepatitis, #vitiligo, #gastric_spasm, #rheumatoid_arthritis, #anxiety, and #muscular_pain. It remediates…

[thejaggedpoisonpath]

Dandelion Tincture (Taraxacum Officinale) ~Some see a weed, some see a wish~ Do you remember blowing the white fluffy tops of a Dandelion flower? Who doesn't?! What's better than a plant that gives wishes when you puff its fluff? In the French language, the Dandelion is referred to as "dent-de-leon", meaning, "tooth of the lion". This "weed" may look innocent & unimpressive, but she packs a punch! Dandelion is a rich source of vitamins A, B complex, and C, as well as minerals such as iron, potassium, & zinc. Traditionally, dandelion roots & leaves were used to support the liver. Tribes boil & drink dandelion extract to help treat digestion problems, skin ailments, inflammation, liver injury, kidney disease, & heartburn. In Traditional Chinese Medicine & European Herbal Medicine, Dandelion is used for breast concerns, liver & gall bladder support, to promote digestion & to support the detoxification process. The bioactive components in dandelion have demonstrated a series of anti-diabetic effects, which are due to the pharmacological actions of components such as sesquiterpene lactones, triterpenes/phytosterols (taraxasterol), phenols, flavonoids, and phenolic acids, comparable to the most used anti-diabetic medication. Studies on dandelion extracts revealed that it may stimulate the release of insulin in pancreatic β-cells, which consequently counteracts the effects of hyperglycemia. Anti-oxidative, anti-inflammatory, anti-hyperglycemic, and anti-diabetic properties. Magically, Dandelion is used in dream work & divination. It is especially effective in spirit communication & summoning, & aids psychic development. Dandelion is associated with wind & air spirits. It is used in invocations to Hekate & other deities associated with death. Dandelion is utilized for purification, manifestation, healing, positivity, & protection against nightmares. The dandelion is masculine in action & associated with the planet Jupiter, the element of air and both Pisces & Sagittarius. #thejaggedpath #dandelion #diabetes #dreamwork #divination #summoning #spiritcommunication #psychic #poisonpath (at Houston, Texas) https://www.instagram.com/p/Cmyc07AujTm/?igshid=NGJjMDIxMWI=

[nutrisentials]

Get the scoop on dandelion as a dietary supplement – why it works and how to use it!

Even though dandelion greens are great in salads, you can also use dandelion roots and stems as dietary supplements! Dandelion is considered one of the most nutritious plants on Earth, but it is also one of the most under-utilized. In this article, you all have the information about this amazing supplement to make sure you are getting the most out of this incredible herb’s health benefits. Let’s get started!

The science behind the benefits of dandelion

The science behind the benefits of dandelion is that the plant contains a number of compounds that have been shown to have health benefits. For example, it contains a compound called taraxasterol that has been shown to have anti-inflammatory properties. Additionally, it contains compounds called sesquiterpene lactones that have been shown to have anti-cancer properties.

Nutrient Profile

It is a rich source of vitamins, minerals, and antioxidants. It is exceptionally high in vitamin A, vitamin C, potassium, and iron. It also contains a range of other nutrients, including calcium, magnesium, phosphorus, and manganese. The nutrient content of dandelion makes it a valuable dietary supplement for people who are looking to improve their overall health and well-being.

Potential Health Benefits

The nutrients may offer a range of health benefits. For example, the high levels of vitamin A and vitamin C may help to boost the immune system. The potassium content may help to regulate blood pressure, while the iron content may help to prevent iron deficiency anaemia. Additionally, the antioxidants in dandelion may help to protect against cell damage and reduce the risk of some chronic diseases.

How to Use Dandelion as a Dietary Supplement

It can be consumed in a variety of ways. The leaves can be eaten fresh or cooked, and the roots can be roasted and ground into a powder. Dandelion tea is also a popular way to consume the herb; the leaves can be used to make a healthy juice. Dandelion supplements are also available in capsule and tablet form.

In Summary

Dandelion is a nutrient-rich herb that has a range of potential health benefits. It is an excellent dietary supplement for those looking for an alternative to traditional options. It is effective in treating various conditions and is relatively safe to use. When taking this natural herb as a dietary supplement, it is essential to follow the directions on the product label and consult with a healthcare professional if necessary.

[jhavelikes]

after the worms were exposed to cocaine.

Reversal of cocaine-induced planarian behavior by parthenolide and related sesquiterpene lactones - PubMed

[accidentalmistress]

TIL that the chemical compound helenalin is a sternutatory substance found in plants of the genus Helenium, aka sneezeweeds. It is a sesquiterpene lactone that irritates the mucous membranes. The pollen of Helenium plants doesn't do much, since it is spread by insects and has grains too large to be carried on the wind. Most of the helenalin is in the leaves and flowers of the plants, which historically were dried by Native Americans and ground into a snuff that was used to induce sneezing.

You know, I've been looking for plants that are native to my area to incorporate into my garden, and Helenium autumnale is distributed across most of North America...

... However, I feel it would be irresponsible if I did not add: helenalin is a toxin. It irritates your mucous membranes — this includes your gastrointestinal system! It can cause nausea, vomiting, diarrhea, and internal bleeding. It also can cause acute liver toxicity and suppress your immune system. If applied to the skin, it can cause contact dermatitis. If enough is ingested, you can die.

That being said, helenalin concentrations in Helenium plants are low, about 0.5%-3% by dry weight, with the highest concentration being in the flowers. Toxicity in humans is not well studied, but lethal doses in other mammals have been shown to range from around 85-105 mg/kg when taken orally. Basically, don't have a sneezeweed salad, and don't start mainlining pure helenalin. If you do try using it, do so at your own risk.

[predictoreports]

Sclareolide is a sesquiterpene lactone Sclareolide: 95-97% product derived from various plant sources including Salvia sclarea, Salvia yosgadensis, and cigar tobacco. It is a close analog of sclareol, a plant antifungal compound. It is used as a fragrance in cosmetics and has been more recently marketed as a weight loss supplement, though there is no clinical evidence to support this effect. The Asia-Pacific Sclareolide market will reach xxx Million USD in 2018 and CAGR xx% 2018-2023. The report begins from overview of Industry Chain structure, and describes industry environment, then analyses market size and forecast of Sclareolide by product, region and application, in addition, this report introduces market competition situation among the vendors and company profile, besides, market price analysis and value chain features are covered in this report.

[tips-from-john]

Does Balmorex Pro Work? BALMOREX PRO REVIEWS – BalmorexPro Reviews – Balmorex Pro

#BalmorexPro #BalmorexProReviews #BalmorexProReview

Does Balmorex Pro really work? What is Balmorex Pro? How to Use Balmorex Pro?

We answer these questions in this comprehensive review of Balmorex Pro. Discover everything you need to know about this advanced muscle, back, and joint health solution.

🤔 What Is Balmorex Pro?

Many people still ask: what is Balmorex Pro?

Balmorex Pro is a revolutionary 27-in-1 formula that provides a comprehensive solution to maintain muscle, back, and joint health. This supplement is meticulously developed to offer total assistance, ensuring long-lasting benefits and supporting the body's overall health in a revolutionary way.

✅ How Does Balmorex Pro Work?

Balmorex Pro is designed to:

Promote optimal blood circulation and combat nerve pain.

Reach inflamed tissues to facilitate relaxation and provide relief from joint pain.

Increase collagen levels to support skin health and improve the proportions of synovial fluid in the joints.

This comprehensive solution is crafted with a unique blend of herbal and organic compounds, providing sustained benefits and relief from various types of bodily discomfort.

❤️ Balmorex Pro Ingredients

Balmorex Pro’s formula includes a powerful combination of natural ingredients:

MSM (Methylsulfonylmethane): A natural compound that is rich in sulfur.

Arnica Oil: Contains sesquiterpene lactones, flavonoids, and phenolic acids.

Hemp Seed Oil: A source of essential fatty acids, vitamins, minerals, and antioxidants.

Indian Incense (Boswellia serrata): Contains boswellic acids that help relieve joint pain and inflammation.

Aloe Vera: Known for its soothing properties and skin health benefits.

Epsom Salt (Magnesium Sulfate): Helps relax muscles and assist in detoxification.

Shea Butter: Rich in vitamins, fatty acids, and antioxidants.

Ginger Root: Contains compounds with anti-inflammatory effects.

📌 What are the Benefits of Using Balmorex Pro?

Improved joint health and mobility.

Reduced inflammation and nerve pain.

Enhanced skin hydration and health.

✳️ Special Offer

Order 6 or 3 pots of Balmorex Pro and receive 2 FREE e-books:

"Shortcut to Wellbeing" - Hack your way to more energy, focus, and performance.

"Upgraded Immunity" - Learn how to strengthen your immune system with expert recommendations.

FAQs

Are there any side effects of using Balmorex Pro?

No, Balmorex Pro is made from 100% natural ingredients and is designed to be safe with no known harmful side effects.

How much does Balmorex Pro cost?

Balmorex Pro is available in different pricing options to suit your needs. Check the official website for current pricing.

Does Balmorex Pro come with a guarantee?

Yes, Balmorex Pro comes with a satisfaction guarantee. If you are not satisfied with the results, you can return the product within a specified period for a full refund.

That concludes the Balmorex Pro Review.

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This is a Balmorex Pro Review. I hope you enjoyed this honest review.

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The post Balmorex Pro Reviews was first published on Flamengo Online.

[indusaroha]

Edible Mushrooms: A Comprehensive Review on Bioactive Compounds with Health Benefits and Processing Aspects

Mushrooms are well-known functional foods due to the presence of a huge quantity of nutraceutical components. These are well recognized for their nutritional importance such as high protein, low fat, and low energy contents. These are rich in minerals such as iron, phosphorus, as well as in vitamins like riboflavin, thiamine, ergosterol, niacin, and ascorbic acid. They also contain bioactive constituents like secondary metabolites (terpenoids, acids, alkaloids, sesquiterpenes, polyphenolic compounds, lactones, sterols, nucleotide analogues, vitamins, and metal chelating agents) and polysaccharides chiefly β-glucans and glycoproteins. Due to the occurrence of biologically active substances, mushrooms can serve as hepatoprotective, immune-potentiating, anti-cancer, anti-viral, and hypocholesterolemic agents. They have great potential to prevent cardiovascular diseases due to their low fat and high fiber contents, as well as being foremost sources of natural antioxidants useful in reducing oxidative damages. However, mushrooms remained underutilized, despite their wide nutritional and bioactive potential. Novel green techniques are being explored for the extraction of bioactive components from edible mushrooms. The current review is intended to deliberate the nutraceutical potential of mushrooms, therapeutic properties, bioactive compounds, health benefits, and processing aspects of edible mushrooms for maintenance, and promotion of a healthy lifestyle.

[speedrangespices]

Top 5 Health Benefits of Bay Leaves

What exactly are Bay Leaves?

There are numerous plants with leaves that are known as "bay leaves," but the genuine bay leaf is technically identified as Laurus nobilis. This is the nutrient-dense type mentioned in the article. Several other types of leaves resemble genuine bay leaves in look and fragrance, but do not have the comparable nutritional value. This is a tiny tree that is endemic to the Mediterranean area. Laurel trees were formerly abundant across the area, but fluctuating temperatures have reduced their numbers. However, these leaves have been used in medicinal and culinary applications for centuries.

What Is the Best Way to Use Bay Leaves?

Bay leaves may be ground into a spice and used to flavor soups and stews, although they are most frequently used intact as a flavour in specific Italian recipes. They are either taken from the meal before consumption or used as a garnish. Whole leaves are used very seldom. Bay leaves do not have a wide variety of culinary purposes, but extracts of these leaves have many medicinal benefits. These leaves are also used in aromatherapy and herbal therapies for a variety of respiratory problems.

The Top 5 Health Advantages of Bay Leaves

1.   Improve Digestion

Bay leaves have historically been used to treat indigestion and other stomach-related illnesses. Bay leaves not only provide excellent flavor and taste to meals, but they also assist in relieving stomach discomfort, gastrointestinal infections, flatulence, bloating, constipation, and diarrhea. They are  used as a diuretic as well. However, further study on the benefits of bay leaves is required to fully establish their effectiveness in improving digestion.

2. Treat Respiratory Disorders

According to a study published in the Biological and Pharmaceutical Bulletin, bay leaves exhibit potent antibacterial capabilities. After extracting the essential oil from bay leaves, it may be combined into a salve and administered to the chest to assist relieve different respiratory problems. This may also be accomplished using a warm fomentation prepared from the leaves. Apply it over the chest and let it on overnight. Because of its inherent antimicrobial properties, inhaling the vapor has a similar effect to aromatherapy and may loosen phlegm and remove harmful germs that may be stuck in your respiratory tracts.

3. Decrease Anxiety and Stress

Linalool oxide is often linked with thyme and basil, although it is also found in bay leaves. This chemical, when used in aromatherapy, may help reduce the amount of stress hormones in the body. Surplus stress hormones may be harmful to your health, therefore bay leaves may be able to calm you down and help you stay comfortable even in stressful situations.

4. Reduce Inflammation

Bay leaf includes chemical agents, referred to as sesquiterpene lactones, which are known to combat inflammation by reducing nitric oxide synthesis, which is one of the reasons of inflammation.

5. Improve Heart Health

Bay leaves include rutin and caffeic acid, both of which help the heart function better. These qualities may assist to fortify the capillary walls of the heart and reduce harmful cholesterol levels. Caffeic acid and rutin are two key chemical components present in bay leaves that may benefit our cardiovascular health. Rutin strengthens capillaries in the heart, while caffeic acid may assist in the elimination of LDL-Cholesterol from the cardiovascular system.

https://www.speedrangespices.com/blog/2021/9/14/top-5-health-benefits-of-bay-leaves

[mcatmemoranda]

P. falciparum presents with trophozoites in RBCs on blood smear with giemsa stain. Malaria in Africa is resistant to choloquine and should be treated with atovaquone-proguanil or artimisinins. P. vivax and P. ovale are the ones that have hypnozoites that can stay dormant in the liver, which require primaquine to eradicate.

Image from Medscape

So I got a question wrong and most people chose the same answer I chose. You have to know in what regions chloroquine-resistant strains of plasmodium live--Africa, Columbia, Peru, Venezuela, Brazil, Bolivia, and most of Asia have chloroquine-resistant malaria, so you can't use chloroquine.

P. falciparum is dominant in Africa and chloroquine resistant. This strain doesn't make hypnozoites, so no need for primaquine. It's in Africa and is resistant to chloroquine, so treat with atovaquone-proguanil or artimisinins.

Wikipedia:

Artemisinin and its semisynthetic derivatives are a group of drugs used against malaria due to Plasmodium falciparum. reatments containing an artemisinin derivative (artemisinin-combination therapies, ACTs) are now standard treatment worldwide for P. falciparum malaria. Artemisinin is isolated from the plant Artemisia annua, sweet wormwood. Chemically, artemisinin is a sesquiterpene lactone containing an unusual peroxide bridge. This endoperoxide 1,2,4-trioxane ring is responsible for the drug's mechanism of action. Few other natural compounds with such a peroxide bridge are known. Artemisinin and its derivatives have been used for the treatment of malarial and parasitic worm (helminth) infections. They have the advantage over other drugs in having an ability to kill faster and kill all the life cycle stages of the parasites.[5] But low bioavailability, poor pharmacokinetic properties and high cost of the drugs are major drawbacks of their use.[6] Use of the drug by itself as a monotherapy is explicitly discouraged by the World Health Organization,[7] as there have been signs that malarial parasites are developing resistance to the drug. Therapies that combine artemisinin or its derivatives with some other antimalarial drug are the preferred treatment for malaria.

Malaria Consortium:

Successful malaria control depends greatly on treatment with efficacious anti-malarial drugs. Malaria endemic countries have a National Malaria Treatment Policy that specifies drugs for treatment of both uncomplicated and severe malaria, malaria in pregnancy and what to do if first line treatment fails.

As the malaria parasite’s resistance develops to existing drugs, new ones need to be introduced. For plasmodium falciparum use of two or more drugs with different modes of action in combination is now recommended to provide adequate cure rate and delay the development of resistance.

Currently artemisinin-based combination therapy (ACT) is recommended for the treatment of P. falciparum malaria. Fast acting artemisinin-based compounds are combined with a drug from a different class. Companion drugs include lumefantrine, mefloquine, amodiaquine, sulfadoxine/pyrimethamine, piperaquine and chlorproguanil/dapsone. Artemisinin derivatives include dihydroartemisinin, artesunate and artemether. A co-formulated drug is one in which two different drugs are combined in one tablet; this is important to ensure both drugs are used.

The benefits of ACTs are their high efficacy, fast action and the reduced likelihood of resistance developing. In order to make best use of them, particularly since no alternative is likely for several years, it is critical to address issues of delivery, access and cost.

Chloroquine is still the first line treatment for P.vivax and P. ovale, while primaquine can be used to treat liver stage parasites of P.vivax, in areas of low malaria transmission if adherence is guaranteed.