#seer thc

[four-eyed-nerd]

Damnnn, it’s been a while since I last posted. Been a tad bit busy after ArtFight and haven’t drawn too much, but I plan on posting the pieces I have done soon! (As well as my ArtFight art, cuz I don’t think I posted that)

These two wonderful lads are from @twidash-ftw-blysse ! Seer is on the left and Myth is on the right, and they’re a part of Blysse’s Links Meet AU! They’re such cool characters and I love their designs so damn much!!!

[alaricseer]

𝐦𝐮𝐬𝐞 𝐩𝐫𝐨𝐟𝐢𝐥𝐞.

real name: Alaric Seer (true name given by his mother is Shara, an incredibly close held secret)

single or taken: verse dependent

abilities or powers: his touch is addictive to humans, inspiring an all-consuming lust, the withdrawal from which can be, and often is, fatal. Physically immortal, can only be killed by fire or iron. Adept in creating/casting glamour. Compulsion. inhuman strength, speed, endurance, and senses. General knowledge of and ability to use magics. Inherited abilities as a Seer from his father, manifesting in visions of possible futures/events through his dreams, though he has no control over this ability and fears it. 

eye color: Green, without glamour the vibrant green of new growth leaves.

hair color: a warm chestnut 

family members: across all verses, his mother is the goddess Ishtar/Inanna, his father a Gancanagh named Tadhg Seer. Jenny Greenteeth is his adoptive mother. He has no siblings, and in some verses has children. 

pets: none   

something they don’t like : being cornered, being looked down on for his high sex drive, others learning of his limited literacy, sleeping alone. 

hobbies  /  activities : Painting (mainly oils), making his own pigments, playing the violin, socializing, being a general pain in the ass.  animals that represent them : not sure, honestly. sexual orientation : pansexual thoughts on marriage / kids : verse dependent. Commitment in a formal way can often lead him to feel trapped, he’s definitely afraid of abandonment, and as a result can react to proposals with a flight response. Not opposed to it, though, with a partner who understands and is patient with his fears. Unlikely to engage in a christian ceremony, however. tl;dr yes, but dont surprise him with it. Ala loves children, but he’s better with young ones, and isnt the best at being a father despite his enthusiasm. Holds children with the same reverence of most of his kind, being as fertility can be a struggle for many of the sidhe.  approach to friendship : enjoys having them, sees no issues with blending friendship and casual intimacy, fiercely loyal to those he bonds with. Can be self absorbed/selfish at times, or go long stretches without contact, so those that he gets along with best are those who call him on those faults, and are willing to forgive. Fastest way to lose him as a friend, is to be disloyal or false. favourite drink : True irish whiskey, any faerie made wine, or strawberry based liqueurs.  favourite place to spend time at : in bed, whether sleeping or in other pursuits. Preferably away from mortal cities, as prolonged time spent around high iron concentration leaves him fatigued and ill.  their type : firm, consistent partners. Patience is also key, as he can be A Lot. He wants love, and to give love, but can be flighty about it and that’s definitely not for everyone. Its not one sided, he makes a lot of mistakes but is very willing to listen, and learn, with a little guidance or at least the space/time to do so. He enjoys powerful people as well, often to his detriment (hello subhoiem), and if he can’t get affection from that type, he’s willing to settle for purely physical attention (healthy or otherwise).  camping or indoors: camping, though away from water if at all possible. 

tagged by: @magioffire

tagging: @pride-of-azkets @evileyeaisling @fierylittleniece @thc-wrong-side-of-heaven @moonboundaddict @sorcerermarlwulf @chaosfaery

[thecannabisblogger]

A Quick Take on Cannabis and Its Effect on Human Health

A Quick Take on Cannabis and Its Effect on Human Health aims to answer these questions. You'll learn about the effects of cannabis on cancer, psychiatric disorders, and long-term health. In this article, we'll look at the long-term effects of cannabis on fertility. If you're pregnant, you can read about the risks and benefits of cannabis during pregnancy. You'll also discover the health risks of smoking cannabis and its effects on fertility.

Psychiatric Disorders

Although there are no clear answers regarding the exact causes of psychiatric disorders caused by cannabis use, studies have shown that the substance can worsen certain symptoms of mental illness. Among patients with dual diagnosis of substance misuse and schizophrenia, cannabis use was associated with the worsening of the latter. Other risk factors were also linked to cannabis use, including alcohol and childhood abuse. Ultimately, it is not possible to say whether or not cannabis use is responsible for the development of psychosis.

The study was conducted with people who were diagnosed with a psychiatric disorder and a control group. The researchers compared the rates of comorbid psychiatric disorders and cannabis use in patients with both conditions. The study was conducted by the Epidemiologic Catchment Area (ECA) survey, which included twenty thousand people in both community and institutional settings. Of those people who reported cannabis use, 50 percent of respondents met the criteria of at least one non-drug mental disorder, including schizophrenia. Troisi et al. (1998) also conducted a study of 133 Italian draftees who reported cannabis use.

Cancer Incidence

The rising incidence of pediatric cancer in the US is directly related to the use of cannabis. Between 1970 and 2017, the rate of pediatric cancer increased by 49%. The effects of cannabis on the testes suggest that the substance may pass on oncogenesis from parent to child. Previous research has linked five major cancers and chromosomal abnormalities to marijuana exposure in the USA. While these studies are limited, they suggest that cannabis may be a contributor to the cancer burden in children.

A large national cancer census dataset was used to assess the relationship between cannabis use and occurrence of cancer. The data used included age-adjusted cancer rates from the CDC and SEER. The drug dataset was derived from a validated nationally representative dataset. The analyses used bivariate statistics, allowing researchers to assess causality directly. The results were consistent with existing data regarding the link between tobacco and cannabis use. Moreover, panelled graphs allowed researchers to display the results of the study across several types of cancers.

Long-term effects of cannabis

Various studies have indicated that cannabis use has detrimental long-term effects on the brain. Chronic cannabis use can cause lowered attention span, increased reaction time, memory loss, and suicidal ideation. In addition, regular use can cause mental health problems, as users are more likely to make hasty decisions and postpone deadlines. Long-term marijuana use may lead to irreversible brain damage from THC.

The study results do not reflect the actual causes of marijuana use. Several recent reviews have found associations between chronic cannabis use and depression, as well as impulsive behavior and suicide. Despite these findings, further research is needed to examine whether marijuana use leads to permanent changes in brain structure. Researchers say it would be helpful to look at data from large-scale studies to find out the long-term effects of cannabis use. These studies should take into account other factors that might influence cannabis use, including genetics and environmental conditions.

Among the long-term effects of cannabis use is a condition called cannabinoid hyperemesis syndrome. Symptoms of this condition include vomiting and nausea and can occur after heavy cannabis use. To prevent the symptoms, heavy cannabis users should avoid using hot tubs or showers. This condition is costly to the healthcare system, and it may have a genetic component. It is difficult to determine whether or not a cannabis user will develop this syndrome, but there are certain indications that cannabis use can alter their IQ.

Long-term effects of cannabis on fertility

There are several possible long-term effects of cannabis on fertility. In addition to its inequitable effects on the endocannabinoid system, marijuana also has adverse effects on fertility. It reduces Sperm count, delays ovulation, and can even increase the risk of miscarriage. If you are struggling with marijuana use and are considering becoming pregnant, seek help from a doctor or fertility specialist.

Current research on marijuana use and fertility is mixed. Some studies have found mixed results, while others have shown no effect at all. One study found that cannabis users had higher levels of luteinizing hormone than non-users. Moreover, animal studies suggested that cannabis use decreased the ability of embryos to implant in the uterus. While further research is needed to determine whether marijuana use affects fertility, the current results are encouraging.

There are also reports that marijuana use affects the menstrual cycle. Women who smoke marijuana regularly have an elevated risk of late ovulation. Marijuana use disrupts the menstrual cycle and results in anovulatory cycles. This may be because marijuana interferes with the luteinizing hormone, which regulates testosterone levels in men. This in turn interferes with the ovulation process.

[cancersfakianakis1]

Contemporary trends of pelvic lymph node dissection at radical cystectomy for urothelial carcinoma of urinary bladder and associated cancer specific mortality and complications: comparison between octogenarian versus younger patients

Publication date: April 2019

Source: Cancer Epidemiology, Volume 59

Author(s): Francesco A. Mistretta, Elio Mazzone, Sophie Knipper, Carlotta Palumbo, Zhe Tian, Sebastiano Nazzani, Fred Saad, Emanuele Montanari, Derya Tilki, Alberto Briganti, Shahrokh F. Shariat, Ottavio de Cobelli, Pierre I. Karakiewicz

Abstract

Background

We analysed contemporary pelvic lymph node dissection (PLND) trend during radical cystectomy (RC) for urothelial carcinoma of urinary bladder (UCUB), as well as PLND association with cancer specific mortality (CSM) and complications after stratification according to octogenarian vs. younger age.

Materials and methods

Within the SEER and NIS databases, respectively 10,427 (T2 and T3 stages) and 19,203 (all T-stages) RC patients (2004–2015) for UCUB were identified. Univariable and multivariable analyses focused on PLND rates, CSM after inverse probability of treatment weighting (IPTW) adjustment, complication rates, length of stay (LOS) and total hospital charge (THC).

Results

Within the SEER database, RC and PLND was performed in 9,406 patients (87.4%), 981 (10.4%) octogenarians and 8,227 younger patients (at, respectively, 83 and 89% PLND). PLND rates increased over time in both patients groups (p < 0.05). PLND was independently associated with lower CSM in both age groups (octogenarians: hazard ratio [HR] 0.51, p < 0.001; younger patients: HR 0.56, p < 0.001). Within the NIS database, PLND was marginally higher associated with overall complications in octogenarians than in younger patients (odd ratio [OR]: 1.32 vs. 1.23, both p < 0.001), with longer LOS (OR: 1.20 vs. 1.08, both p < 0.001), higher THC (relative increase: 6933 vs. 4484, both p < 0.001), but not with higher in-hospital mortality.

Conclusions

PLND is associated with lower CSM, but its rate lags in octogenarian vs. younger patients. In both age groups, PLND leads to marginally higher complications, longer LOS and higher THC, but not to higher in-hospital mortality.

http://bit.ly/2S2b26Q

[hyphywaifu]

Hallucinogens

     Lysergic acid diethylamide (LSD) was the first hallucinogen that was ever discovered. It was accidentally discovered in 1938 by Sandoz Laboratories while they were in search of a new analeptic agent. The first person to experiment with LSD was a chemist named Albert Hoffman. When he first took the drug he began experiencing hallucinations. LSD was thought to help people express repressed emotions and was soon marketed to the public in 1974. To this day, 229,000 Americans ages 12 and older have experimented with LSD and 33,000 with PCP according to the National Survey on Drug Use and Health and Substance Abuse and Mental Health Services Administration in 2013.

     Lysergic acid diethylamide (LSD), methylenedioxymethamphetamine (MDMA),  salvia divinorum (salvia), psilocybin (mushrooms), and cannabis sativa (marijuana, THC) are some popular and well known drugs today. LSD is usually used when people just want to have fun and experience hallucinations for the fun of it. LSD is also mostly used at parties or just during a kickback with some friends. Some common street names for LSD include: acid, sunshine, boomers, blue chairs, Loony Toons, pane, and cubes. People use salvia as a way to feel spiritual and/or to help them meditate, self-reflect, and contemplate about anything such as life. People eat shrooms to feel the same effect as LSD (hallucinate). It’s basically the same thing except edible form. Some common street names for salvia: sage of the seers, diviner’s sage, magic mint, lady salvia, and purple sticky. MDMA is known as the “party drug”. At a lot of parties, raves, and concerts today, people will take MDMA for a various of reasons. Some take it to feel closer and actually feel the music, others take it to feel happy just for a few hours, some take it to let out their true emotions and be anxiety free. Some users may also experience very mild hallucinations while on MDMA. Common street names for MDMA include: ecstasy, Molly, e, moon rocks, XTC.  Marijuana is one of the most common drugs ever used in our society today. Marijuana is “known” to help relieve pain, anxiety, and stress. Weed, cannabis, green, pot, grass, 420, and Mary Jane are all common street names for marijuana.

     Most drugs are all taken a different way. Each way a user takes the drug affects them differently.  LSD is taken orally by placing one tab (or more if desired) on the tongue and waiting for it to melt. One “hit” of LSD is usually 120-150ug. The drug itself is a liquid and it is absorbed into blotting paper which people then put on their tongue and wait for it to dissolve. It is most common for people to do the blotting paper method when wanting to consume the drug but it is also possible to take the drug as a liquid onto your skin, into the mouth, etc. Salvia is usually smoked (since it is a leaf) or it can also be drank as a water-based drink/tea. A “normal” dose of salvia would be .2-.5 grams. The dose is small but when the chemicals in the drug hits you, the users feel it hard.  It’s pretty obvious how shrooms (mushrooms) should be taken. Shrooms are usually eaten. Some people will put it on their food and eat it since it has a bitter and weird taste and one dose of it is 1.5-2 grams. Molly is taken orally as a pill in capsule or pressed pill form and can also be smoked or snorted. A “good” dosage of MDMA for first time users would be 50mg-60mg and it hits faster if it’s in pill form rather than capsule. It also depends on how much food was eaten before taking the drug. Users of MDMA must know that not all pills are pure and they can always be cut in with another drug. Capsule pills of MDMA are mostly pure while pressed pills of MDMA are mixed in with other drugs such as meth, acid, speed and more. Lastly, marijuana is a plant and it is smoked. It is always important for the user to test their drugs and to also always know what they’re taking and know how to take proper action when something happens.

     Some hallucinogens have same effects while others have extremely different ones. The neurotransmitters that are most impacted by hallucinogens is serotonin. The effects of LSD are similar to those effects of shrooms. LSD causes illusions and hallucinations and it also alters the perception of time and distance. People on LSD will usually see random patterns and “halos” of light. Trips on this drug can last from 8-12 hours depending on how much of a dosage is taken at one time. It can take up to a few minutes or hours for the user to “feel the drug”. The minimal therapeutic dose is 120ug while minimal toxic dose could be about 1,000 micrograms. When on salvia, it is nearly impossible for people to tell the difference from fantasy and reality. Effects of salvia are only strong for 5-6 minutes but the drug can last up to 30 minutes in your body. Most users experience “scary” and intense fantasies and the minimal therapeutic dose is .2 grams while the minimal toxic dose is anything above .5 grams. Shrooms has basically the same effects of LSD but can last from 4-6 hours. Some users can experience happy moods and the minimal therapeutic dose is 1.5 grams while the minimal toxic dose is 1,000 micrograms. Depending on the dose, MDMA can last from 4-6 hours. It heightens the senses, causes teeth grinding and dehydration. The minimal therapeutic dose of this drug is 60 mg while the minimal toxic dose is 200 mg. Effects of marijuana lasts differently in everyone. It causes increased appetite, anxiety, paranoia, lack of motivation, and fatigue.

     Most drugs including prescription drugs have side effects. There are of course many synthetic and research chemical versions of drugs. These versions are always more dangerous than the pure drug itself. The synthetic versions of drugs will have different types of effects, side effects, and warnings than the purer versions.  Some more extreme than others, some mild, and some drugs surprisingly don’t have any side effects. According to Appendix B in our textbook, LSD does not have any side effects but according to DrugAbuse.gov, short-term effects of LSD include increased blood pressure, heart rate, and body temperature, dizziness and sleeplessness, loss of appetite, dry mouth, sweating, numbness, weakness, tremors, impulsiveness, and rapid emotional changes that can range from fear to euphoria. Long-term effects of LSD are sometimes extremely disturbing with recurrent, and irreversible. Long-term effects are accompanied by dysphoria, a sense of depression and malaise. Even if someone were to stop taking the drug, hallucinations would still be recurrent. Persistent psychosis is also prominent. Psychosis is a condition of dissociation from the real world including hallucinations and delusions. People with psychosis have radically disorganized thought patterns, distortions of perceived reality and dramatic mood swings. Psychosis does not happen to everyone who does LSD but it is also still a risk to many. Long-term effects of LSD on the body include hyperthermia, or overheating, cardiovascular collapse, or sudden heart failure. Treatments for LSD abuse and psilocybin are basically the same. Treatments include behavior modification, counseling, and psychological treatment. The side effects of salvia include headaches, racing thoughts, insomnia, irritability, extreme dizziness, drowsiness, sleeping difficulty, mood effects, lightheadedness, increased insight, strange thoughts, a floating feeling, and calmness or yawning. Salvia long-term effects on the brain and body include brain damage, irritated lungs, increased risk of suicide, increased self-confidence, increased or decreased concentration. It is highly recommended for the user to have someone who is sober in the room to watch the user so that they can prevent injury if it may occur. Psilocybin side effects include headaches, feelings of relaxation, panic reactions, introspective/spiritual experiences, intense fear, paranoia, nausea, anxiety, and dizziness. The long-term effects of psilocybin are basically the same as LSD. MDMA side effects include muscles aches, drowsiness, depression, acne, impaired judgment, false sense of affection, confusion, severe anxiety, paranoia, drug cravings, faintness, chills, and swelling, teeth clenching, blurred vision, and insomnia. Some long-term effects of MDMA include long-lasting brain damage that affects thought and memory, damage to portions of the brain that regulate critical functions such as learning, sleep, and emotion, kidney failure, psychosis, convulsions, cardiovascular collapse, hemorrhaging, and death. Some treatments for chronic drug use of MDMA include individual, group and family therapy, 12-Step education, cognitive behavioral therapy, dialectical behavioral therapy, recreation therapy and more.  Marijuana actually has many side effects and long-term effects.  Side effects of this drug include dry mouth, dizziness, and increased appetite, while long-term side effects include memory impairment, lack of motivation, depression, paranoia/anxiety, addiction, and lung problems. Treatments for marijuana use disorders include cognitive-behavioral therapy, contingency management, and motivational enhancement therapy.

     In conclusion, if someone were to want to use drugs, they should always take precautions and know the side effects and long term effects that comes with doing drugs. It is important for people to always do their research if they were to want to do drugs. Doing research before taking a drug is important to do so that when the drug is being used, the person will not feel anxious and have a bad trip on it.

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Blakinger / Substance.com, Keri. "10 Surprising Facts About the History of Hallucinogens." Alternet. N.p., n.d. Web. 12 Oct. 2016. <http://www.alternet.org/drugs/10-surprising-facts-about-history-hallucinogens>.

"How Widespread Is the Abuse of Hallucinogens and Dissociative Drugs?" National Institute on Drug Abuse (NIDA). N.p., n.d. Web. 13 Oct. 2016. <https://www.drugabuse.gov/publications/research-reports/hallucinogens-dissociative-drugs/why-do-people-take-hallucinogens>.

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Hanson, Glen, Peter J. Venturelli, and Annette E. Fleckenstein. Drugs and Society. 12th ed. N.p.: n.p., n.d. Print.

"How Do Hallucinogens (LSD, Psilocybin, Peyote, DMT, and Ayahuasca) Affect the Brain and Body?"National Institute on Drug Abuse (NIDA). N.p., n.d. Web. 13 Oct. 2016. <https://www.drugabuse.gov/publications/research-reports/hallucinogens-dissociative-drugs/where-can-i-get-more-scientific-information-hallucinogens-diss>.

[twidash-ftw-blysse]

I LOVE THEEMMMMM

Damnnn, it’s been a while since I last posted. Been a tad bit busy after ArtFight and haven’t drawn too much, but I plan on posting the pieces I have done soon! (As well as my ArtFight art, cuz I don’t think I posted that)

These two wonderful lads are from @twidash-ftw-blysse ! Seer is on the left and Myth is on the right, and they’re a part of Blysse’s Links Meet AU! They’re such cool characters and I love their designs so damn much!!!