#prolonged asting
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How do you feel?


This is my headcanon to the fact that Ford felt and saw ABSOLUTLY everything that was happening around him. He wasn't just a golden statue. He was sealed. It was like a prolonged sleep paralysis, a claustrophobic attack.
My telegram: AstelyS
#billford#gravity falls stanford#stanford pines#bill x ford#bill x stanford#Art#digital art#gravity falls
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hehe scenario. jupeter coming out the other side of All That with a bit of 'wow you're just straight up a bit codependent but maybe that's actually the best-case scenario for you right now carry on fellas'
oh they've Had Their Talk in the aftermath, and, okay, it's agreed that they are Not Doing Romance because Nureyev needs Time To Grieve and it would be better to Take The Pressure Off Of Being In A Relationship and they will Reevaluate when Nureyev's had a chance to be a guy who doesn't have to worry about where his next meal is coming from. but also Like Hell is Juno just going to Leave Him Alone after all this. and the result is that they spend the Big Crash just. completely unhinged about each other. Nureyev's shot past 'feeling vulnerable around Juno scares the shit out of him' and well into 'raw nerves and gaping wounds and compound trauma and feeling vulnerable about literally anything and everything all the time and being around Juno is integral to not spiraling into the abandonment hell vortex'. meanwhile Juno's like 'holy shit Nureyev is letting me be there for him. this is already incredible progress'
u think they were insufferable on the Carte Blanche well. on the Carte Blanche Nureyev was still working on things like trusting Juno enough to let him back in at all and he Had An Image To Maintain and lots of Private Stuff to Deal With and Juno was still figuring out how not to be a prickly ass all the time and 'when is it appropriate to give your bf his space when your default mode is to Investigate Shit' and none of that is a going concern right now
'sometimes you gotta be a little bit mentally ill to handle the mental illness' they have so much separation anxiety and they are clipping their carabiners together. hooking pinky fingers and following each other when one needs to do something in the next room. where's Nureyev? sitting in Juno's lap again. his ass is experiencing 'nervous system doesn't know how to respond to the sudden removal of constant crushing dread and just goes fucking haywire at unpredictable intervals'. he gets random-ass panic attacks and there's only so much the breathing exercises and the grounding exercises and self-soothing techniques can do compared to 'Juno is here and he's fine and he's safe and he is more than happily providing prolonged physical contact' to get him to calm down on a physiological level
meanwhile Juno's like 'i chased this idiot across half the galaxy because he wouldn't ask for help and had to deal with him being all stone-faced and cold about it, do I look like i mind that he's clingy now? a lady does not need his personal space at this time. a lady is living for this. a lady is also maybe feeling clingy have u considered that'
everyone who isn't rita (idek who. melee? the other vivopolis refugees??) is assuming they are just getting a very bad grade in taking it slow and are barely humoring them about it. and neither bothers with denying the boyfriend allegations but it's not bc it's true it's they're just. too exhausted to get defensive about it
rita: and i mean they ain't actually smooching too loud in the kitchen or whatever
melee probably: he just came out of Juno's room wearing Juno's shirt
juno: he's a thief that's his shirt now
(12 hours earlier:)
nureyev: (shows up to juno's room at 3am) im sorry for waking you i had nightmares about [the bomb/the carte blanche raid/dokana capturing you] i just needed to see that you were alive and make sure im in the reality timeline and then i will go back to-
juno: get in loser we're watching bad cops
rita: hi mista' n do you want some of this blanket
nureyev: that's very kind but im afraid im
juno: yeah hold up he's like really sweaty im gonna get him a clean shirt
nureyev: you really don't need to-
juno: how are you even still standing up when you're shaking like that
nureyev: that is. an excellent question
juno: anyway welcome to the club i fired rita like an hour ago bc i had nightmares about her dying on the asteroid
rita: i had one where i was gettin chased by this big stompy plant monster with lotsa teeth and i had to distract it by throwing all my snacks behind me and then i was outta snacks and then i was up getting more snacks when mista' steel fired me
rita: you know i think only reason i ain't got separation anxiety about mista' steel is because we spent all that time in the ruby together while we were chasin' after you and that gets a gal over it real fast
juno: thanks rita :P
#good morning i am once again committing my little scenarios#hypothetical denouement nonsense#this is not even remotely legit speculation i am just saying words recreationally#the penumbra podcast#juno steel#peter nureyev
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Sorry that I'm just a rando wandering onto ur blog but the asc ast people are so wild
Do you think they realize you can have your hot dominant vampire fantasies AND have him still actually love tav... while he's still a spawn. Do They Know.
(they clearly don't)
Also I find it funny that these ppl are saying the same shit about spawn astarion that he (at his most vulnerable moments as a spawn, or all the time as ascended) thinks of himself as a spawn. That he's weak.
Like the whole point is that he's NOT weak... He has toxic ideas about power and strength from his prolonged trauma and abuse... Keep up people!
you're absolutely correct, dear nonny.
if they think they getting some kind of dom/sub relationship there in ascendant path - newsflash, you're not, because a dom would never treat sub like they're less (if you want a healthy dom/sub, look no further than iron bull x dorian or iron bull x mc in dragon age inquisition)
and yeah, they're indeed saying the same shit he was so insecure about the whole time - that he's worthless, pathetic, weak...while they romanced him through the entire game. so why did you then if you thought all of that?
logic = zero
Astarion's story has two paths:
affirm his fears, insecurities, affirm the world sucks so you need to take it under control (your lover included) to feel safe
empower him mentally, show him he's enough the way he is, that he doesn't have to be scared
both are valid but it's clear as day which one is the healthy one
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Importance of AstraGin in Daily Sports Nutrition

AstraGin is acquiring recognition in the field of sports nutrition for its substantial role in improving nutrition absorption. This all-natural compound helps athletes optimize the benefits of their supplements by enhancing the bioavailability of key vitamins, minerals, and amino acids. As suitable nutrient uptake is essential for efficiency, understanding how AstraGin features in this circumstance might supply professional athletes with a critical advantage. What stays to be discovered are the broader ramifications of its impacts on general health and performance.
Recognizing AstraGin and Its Resources
Although AstraGin is commonly eclipsed by more popular supplements, its relevance in sports nutrition is acquiring recognition because of its ability to boost nutrient absorption. Derived from the roots of Astragalus membranaceus and Panax notoginseng, AstraGin comprises key ingredients such as astragaloside IV and ginsenosides. These bioactive compounds have actually been revealed to improve the absorption of necessary nutrients like amino acids, vitamins, and minerals. By including AstraGin into a sports nutrition routine, athletes can optimize the effectiveness of their supplements, guaranteeing that their bodies obtain the needed nutrients for peak performance and recuperation, making it a useful addition to any type of athlete's diet.
The Role of AstraGin in Nutrient Absorption
AstraGin plays a pivotal role in improving vitamins and mineral absorption, making it a considerable component of sports nutrition. This natural substance, originated from Panax notoginseng and Astragalus membranaceus, has been revealed to boost the bioavailability of essential nutrients. The AstraGin benefits prolong beyond simple absorption; it efficiently raises the uptake of amino acids, vitamins, and minerals, consequently optimizing their effectiveness. Study shows that AstraGin impacts include boosting digestive transportation mechanisms, which helps with a much more reliable nutrient distribution system. Integrating AstraGin into dietary regimens can consequently maximize vitamins and mineral absorption, eventually sustaining professional athletes in accomplishing their health and fitness and efficiency goals.
Prospective Advantages for Athletic Performance
While many factors add to sports performance, the assimilation of AstraGin into a sports nutrition program can significantly enhance results. This AstraGin supplement is specifically helpful for bodybuilding, as it enhances the absorption of crucial nutrients that support muscular tissue growth and healing. Enhanced nutrient uptake allows professional athletes to achieve better energy levels and improved endurance, essential for peak performance. In addition, AstraGin might help in lowering exercise-induced tiredness, promoting more intense training sessions. As a result, athletes incorporating this supplement right into their day-to-day routine can experience considerable improvements in their total athletic performance, making it an important addition to any type of sports nutrition strategy.
Sustaining Intestine Health With AstraGin
Sports performance is intricately linked to total health, and gut health and wellness plays a significant role in this equation. AstraGin, a natural substance originated from Astragalus membranaceus and Panax notoginseng, is acquiring focus in sport nourishment for its efficiency in sustaining digestive tract health and wellness. Research suggests that AstraGin makes use of boost vitamins and mineral absorption, thus boosting digestion efficiency and total health. This increased bioavailability of vital nutrients is vital for athletes, as ideal health straight influences performance. By integrating AstraGin into daily regimens, athletes can strengthen their intestine health and wellness, leading to enhanced recovery, maintained energy levels, and eventually, boosted sports results.
Final thought
In recap, AstraGin is an essential part of everyday sports nutrition, substantially boosting the bioavailability of key nutrients. Its capability to improve the absorption of amino acids, vitamins, and minerals straight supports muscle growth, recuperation, and overall athletic performance. Furthermore, by promoting intestine health, AstraGin ensures reliable food digestion and continual energy levels. Integrating AstraGin into an extensive nutrition routine encourages professional athletes to maximize their efficiency and attain their peak capacity in their particular sports.
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WHY RAHU IN 8TH HOUSE IS SUITABLE FOR RESEARCH FIELDS AS PER VEDIC ASTROLOGY
In Vedic astrology, Rahu in the 8th house is a powerful and often misunderstood placement. It can bring intense experiences, transformation, and a deep pull toward the hidden aspects of life. While Rahu is often feared due to its karmic nature and its tendency to generate illusions or obsessions, its placement in the 8th house can be incredibly fruitful—especially for those inclined toward research, investigation, or fields that require deep psychological or metaphysical insight.
Why is Rahu in the 8th House Favorable for Research?
The 8th house is traditionally associated with:
Secrets and the occult
Death and rebirth (both literal and symbolic)
Hidden knowledge
Inheritance and legacy
Sudden events and transformation
Psychology and mysticism
Rahu, on the other hand, is a shadow planet that thrives on obsession, unconventionality, and breaking norms. When Rahu is placed in the 8th house, it drives the native toward uncovering what lies beneath the surface—whether in the human mind, esoteric texts, ancient sciences, or unexplored domains. This creates a natural synergy with careers or interests that involve:
Scientific or medical research
Forensic investigation
Psychology and psychotherapy
Astrology, tantra, and occult studies
Historical or archaeological analysis
Deep financial research (e.g., stock markets, cryptocurrency, forensic accounting)
Because Rahu is never satisfied with superficial understanding, its placement here makes the individual relentless in the pursuit of depth and truth. This hunger for knowledge often translates into an intuitive or even obsessive drive to explore topics that others might find too dark, taboo, or difficult to understand.
Key Astrological Factors Enhancing Research Potential
To determine the full power of Rahu in the 8th house, other planetary conditions must be considered:
1. Rahu’s Dispositor (Lord of the 8th House):
o If the dispositor is strong and well-placed (e.g., in its own sign or exalted), Rahu’s energies are more channelized and productive.
o For example, if Rahu is in the 8th house in Scorpio, its dispositor is Mars. A well-placed Mars in a friendly house or sign boosts research capability and physical endurance.
2. Aspect or Conjunctions:
o Benefic aspects (like from Jupiter or Mercury) can add intelligence, clarity, and ethical motivation to Rahu’s intense energy.
o Malefic conjunctions (like with Ketu or Saturn) can deepen the transformative experience but might also bring isolation or obsession.
3. Nakshatra of Rahu:
o The nakshatra provides psychological insight into the nature of the native's obsessions and research inclinations. For example:
§ Ashlesha: interest in secrets, snakes, and hidden power.
§ Moola: digging deep into root causes, excellent for spiritual or scientific research.
4. Strength of the Lagna (Ascendant):
o A strong ascendant provides the vitality and balance needed to handle the psychological intensity of this placement.
How to Effectively Leverage Rahu in the 8th House
1. Choose a Career That Rewards Depth:
o Fields that require prolonged focus, patience, and deep inquiry suit you best. This includes research in medicine, biotechnology, law enforcement, forensic science, psychology, and esoteric studies.
2. Embrace Transformation:
o Your life may undergo sudden changes or intense transformations. Instead of resisting them, work with them. These shifts often lead you toward your deeper calling.
3. Practice Discipline and Grounding:
o Since Rahu can cause obsession or erratic thinking, regular practices like meditation, journaling, or grounding exercises can help you maintain focus and emotional stability.
4. Channel Your Curiosity Productively:
o You may feel drawn to taboo topics. As long as you approach them ethically and with the right guidance, this can become a strength.
5. Study Occult or Spiritual Sciences:
o This placement is especially favorable for learning Vedic astrology, tantra, or other mystical traditions. These fields not only satisfy Rahu’s hunger for hidden knowledge but also help you navigate its influence wisely.
6. Work on Psychological Resilience:
o The 8th house is linked with trauma and healing. Your ability to face and process psychological depths can help others as well, especially in therapy or counseling roles.
7. Watch for Manipulative Tendencies:
o Rahu can also bring shadow traits—manipulation, secrecy, or obsession. Stay aware of these tendencies and use your insights for constructive purposes.
Final Thoughts
Rahu in the 8th house is like a torch in the darkness—it allows you to explore the mysterious, the hidden, and the forbidden. With proper self-awareness and guidance, this placement can give you the perseverance and curiosity needed for a successful research career or spiritual quest.
Instead of fearing its intensity, use it as a gateway to deeper understanding, transformation, and purpose.

#Astrology#rahuAstrology#astrology#horoscope#vedicastrology#indianastrology#vedicastrologer#astrologer#predictions#destiny#psychic#kundli#jyotish#daily horoscope#daily astrology#indian jyotish#vedic jyotish
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Understanding Liver Function Tests: Purpose, Process, and Interpretation
Overview
Liver function tests (LFTs) are blood tests used to assess liver health by measuring specific enzymes and proteins in the blood. These tests help diagnose underlying conditions, monitor existing liver diseases, and evaluate the impact of medications or treatments. They can be conducted at a blood testing lab or through lab tests at home for added convenience.
Some LFTs assess the liver's ability to produce essential proteins and process bilirubin, a waste product derived from red blood cells. Others measure enzyme levels that indicate liver cell damage. However, abnormal test results do not always signify liver disease. A healthcare provider interprets these results in the context of your overall health.

Why Liver Function Tests Are Conducted
Liver function tests serve various purposes, including:
Screening for liver infections such as hepatitis.
Monitoring conditions like viral or alcoholic hepatitis and assessing treatment efficacy.
Detecting severe conditions like cirrhosis (liver scarring).
Evaluating potential side effects of medications.
Since LFTs measure enzyme and protein levels, deviations from the normal range can signal liver problems. The pattern and extent of these changes provide valuable clues about underlying health issues. Individuals can opt for blood tests for liver function at a blood testing lab or choose lab tests at home for ease and accessibility.
Common Liver Function Tests
Alanine Transaminase (ALT): This enzyme aids in protein metabolism. Elevated ALT levels may indicate liver damage. Also known as SGPT.
Aspartate Transaminase (AST): Helps break down amino acids. Increased levels may suggest liver disease or muscle damage. Also referred to as SGOT.
Alkaline Phosphatase (ALP): Found in the liver and bones, this enzyme aids protein breakdown. Elevated ALP levels may indicate bile duct obstruction or bone disorders.
Albumin and Total Protein: Albumin, a protein produced by the liver, is essential for immune function and other bodily processes. Low levels may indicate liver disease or other conditions like kidney disease.
Bilirubin: A waste product from red blood cell breakdown, bilirubin is processed by the liver and excreted in stool. High levels may indicate liver disease or bile duct obstruction.
Gamma-Glutamyltransferase (GGT): A liver enzyme that, when elevated, may suggest liver or bile duct damage.
L-Lactate Dehydrogenase (LD): High LD levels can indicate liver damage but may also be linked to other conditions.
Prothrombin Time (PT): Measures how long it takes blood to clot. Prolonged PT may indicate liver disease or the effects of blood-thinning medications.
Potential Risks of the Test
Liver function tests require a blood sample, typically drawn from a vein in the arm. The procedure carries minimal risks, such as mild bruising or soreness at the puncture site. Serious complications are rare.
Preparation for the Test
Certain foods and medications can affect test results. Your doctor may advise you to fast and avoid specific medications before the test for accurate readings.
What to Expect During and After the Test
A healthcare professional will insert a small needle into a vein in your arm to collect the blood sample. You may feel a brief prick or mild discomfort. After the test, the sample is sent to a blood testing lab for analysis. Results may be available within hours if processed on-site or within days if sent to an external lab. Individuals opting for lab tests at home may receive their results through digital reports.
Interpreting the Results
Standard reference ranges for blood tests for liver function include:
ALT: 7-55 U/L
AST: 8-48 U/L
ALP: 40-129 U/L
Albumin: 3.5-5.0 g/dL
Total Protein: 6.3-7.9 g/dL
Bilirubin: 0.1-1.2 mg/dL
GGT: 8-61 U/L
LD: 122-222 U/L
PT: 9.4-12.5 seconds
These values may vary based on laboratory standards and patient demographics such as age and gender. Your healthcare provider will interpret the results within the broader context of your health history and symptoms. Additional tests and imaging may be necessary for a definitive diagnosis.
Conclusion
Liver function tests are vital tools for diagnosing and monitoring liver health. While abnormal results may indicate potential issues, further evaluation is often required to determine the exact cause. Consulting a healthcare professional ensures accurate interpretation and appropriate follow-up care. Whether conducted at a blood testing lab or through lab tests at home, these tests play a crucial role in maintaining liver health.
#blood testing lab#lab tests at home#vitamin deficiency tests#blood tests for liver function#leading blood testing lab in mumbai#thane & airoli#b vitamin testing centre#b vitamin testing service
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Antimicrobial Coatings Market Business Segmentation by Revenue, Present Scenario and Growth Prospects 2033
Antimicrobial Coatings: A Growing Antimicrobial Coatings Market for Health and Hygiene
Antimicrobial coatings are specialized materials that possess the ability to inhibit the Antimicrobial Coatings Market growth of microorganisms, such as bacteria, fungi, and viruses. These coatings have gained significant traction in recent years due to their potential to improve public health, reduce the spread of infections, and enhance product durability.
Request Sample Copy:
https://wemarketresearch.com/reports/request-free-sample-pdf/antimicrobial-coatings-market/45
Key Drivers of the Antimicrobial Coatings Market
Rising Healthcare Concerns: The increasing prevalence of healthcare-associated infections (HAIs) has created a pressing need for antimicrobial coatings in hospitals, clinics, and other healthcare settings.
Food Safety: Antimicrobial coatings are used to protect food surfaces from contamination, ensuring food safety and preventing foodborne illnesses.
Consumer Demand: Consumers are becoming more aware of hygiene and are seeking products with antimicrobial properties for their homes and personal use.
Industrial Applications: Antimicrobial coatings are used in various industries, including aerospace, automotive, and marine, to protect surfaces from microbial degradation and corrosion.
Types of Antimicrobial Coatings
Biocidal Coatings: These coatings contain active ingredients that directly kill or inhibit the growth of microorganisms. Examples include coatings containing silver, copper, or quaternary ammonium compounds.
Self-Cleaning Coatings: These coatings have the ability to degrade organic matter, preventing the growth of microorganisms.
Photocatalytic Coatings: These coatings use sunlight to generate reactive oxygen species that can kill microorganisms.
Global Antimicrobial Coatings Market- Segment Analysis
By Type
Metallic
Silver
Copper
Others
Non Metallic
Polymeric
Organic
Others
Key Campany
BASF SE
Axalta Coating Systems
Diamond Vogel
Nippon Paint Company
, PPG Industries Coatings
DuPont
Koninklijke DSM N.V.
RPM International
The Sherwin-Williams Company
AK Coatings
, Biointeractions Ltd.
Lonza Group Ltd.
Covalon Technologies Ltd.
Sono-Tek Corporation
Trop Corporation
Specialty Coating Systems Inc.
Sciessent LLC
Mankiewicz Gebr. & Co. (GmbH & Co. KG)
Hydromer
BIO-FENCE
AST Products Inc.
Others
Antimicrobial Coatings Market Applications Across Industries
Healthcare
One of the most significant applications of antimicrobial coatings is in the healthcare sector. Hospitals and clinics are high-risk environments where infections can spread rapidly. Antimicrobial coatings are applied to medical devices, hospital surfaces, and even furniture to minimize the risk of healthcare-associated infections (HAIs). By effectively reducing microbial load, these coatings play a vital role in patient safety and improving health outcomes.
Food and Beverage
In the food and beverage industry, maintaining hygiene is critical. Antimicrobial coatings are used on surfaces such as countertops, equipment, and packaging materials to prevent contamination. These coatings not only enhance food safety but also prolong shelf life by inhibiting microbial growth.
Construction
The construction sector is increasingly adopting antimicrobial coatings for various applications. From wall paints to flooring materials, these coatings can prevent mold and mildew growth in buildings, promoting healthier indoor environments. This application is especially crucial in regions with high humidity or in facilities like schools and gyms, where cleanliness is essential.
Consumer Products
The rise in health consciousness among consumers has led to the incorporation of antimicrobial coatings in everyday products. Items like smartphones, kitchen appliances, and even clothing are now available with antimicrobial properties, appealing to health-minded consumers looking for added protection.
Antimicrobial Coatings Market Trends and Challenges
Technological Advancements: Ongoing research and development are leading to the development of new and improved antimicrobial coatings with enhanced properties.
Regulatory Landscape: Compliance with regulatory standards, such as FDA regulations for food contact surfaces, is essential for market entry.
Cost Considerations: The cost of antimicrobial coatings can be higher than traditional coatings, which may limit their adoption in certain applications.
Consumer Perception: Educating consumers about the benefits of antimicrobial coatings is crucial for market growth.
Future Outlook
The Antimicrobial Coatings Market is expected to continue growing, driven by increasing awareness of public health and hygiene concerns. As technology advances and regulatory frameworks evolve, we can anticipate the development of even more innovative and effective antimicrobial coatings. These coatings have the potential to revolutionize various industries and contribute to a healthier and safer world.
Conclusion
The antimicrobial coatings market is set for Remarkable growth as industries prioritize hygiene and safety. With applications spanning healthcare, food and beverage, construction, and consumer products, these coatings are becoming indispensable in our daily lives. As we move forward, continuous innovation and awareness will be key drivers in shaping the future of this dynamic Antimicrobial Coatings Market. Investing in antimicrobial coatings not only enhances safety but also contributes to a healthier environment for everyone.
#Antimicrobial Coatings Market Share#Antimicrobial Coatings Market Demand#Antimicrobial Coatings Market Scope#Antimicrobial Coatings Market Analysis#Antimicrobial Coatings Market Trend
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Growing splendor Sustainably: green art tasks
In a world more and more aware of environmental problems, the artwork community has embraced the undertaking of creating beauty sustainable. Green artwork initiatives aren't only useful for the environment but also encourage creativity through the usage of materials that might be regularly unnoticed. This article explores the concepts of green art, and numerous sustainable substances, and presents ideas for responsibilities that combine artistry with environmental focuss

The idea of green artwork
Eco-friendly art makes a specialty of sustainability and minimizing the environmental impact of art creation. This includes using recycled, upcycled, and natural materials, reducing w
Aste, and retaining off dangerous chemical compounds. The intention is to create paintings this is adorable and sustainable, selling a deeper reference to nature and galvanizing others to think about their environmental footprint.
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Sustainable substances
1. Recycled Paper: as an alternative to buying new paper, artists can use paper made from recycled materials. This helps reduce deforestation and saves power.
2. Natural Pigments: Dyes and paints may be crafted from herbal resources like plants, minerals, or even insects, preserving the toxic chemical substances found in lots of business products.
3. Observed gadgets: items that would otherwise be discarded, together with bottle caps, vintage magazines, or material scraps, can be repurposed into artwork.
4. Biodegradable Glue and Tape: the use of adhesives that spoil down simply reduces the prolonged-term environmental impact of painting tasks.
Art Workventure thoughts
1. Recycled college: collect antique magazines, newspapers, and unique paper substances to create a college. This task no longer best repurposes paper waste however also allows a huge range of inventive expression. By way of the use of cutting and layering unique textures and colorings, artists can create specific and compelling compositions.
2. Nature Sculptures: Use natural substances like twigs, stones, leaves, and flowers to create sculptures. The materials can be amassed in your environment without causing harm to the surroundings. Nature sculptures can range from easy arrangements to more complex designs, reflecting the splendor of the natural global.
Three. Eco-Prints: Eco-printing involves using flowers, leaves, and flora to create prints on cloth or paper. Using the way of setting plant materials on the ground and using warm temperatures, the herbal pigments switch to the medium, developing stunning, natural styles. This technique is not only the simplest sustainable but also produces precise and touchy designs.
Four Upcycled jewelry: vintage earrings, buttons, and unique small gadgets can be upcycled into new, stylish pieces. With the useful resource of mixing precise elements, you can create one-of-a-type add-ons that reflect your style even as decreasing waste.
5. Mostly through the combination of those cited natural pigments with a binder kind gum Arabic or egg yolk consequences in inexperienced paints that can be used for several painting initiatives.
Sed artwork:
Create your paints with the use of plant-primarily based pigments. As an example, beetroot can pr, produce a rich purple color, at the same time as turmeric yields a vibrant yellow.
6. Bottle Cap Mosaics: accumulate caps of bottles and use them to make colorful mosaics. This task not only recycles plastic waste but also encourages innovative questioning and problem-fixing as you lay and gather your artwork.

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End
Inexperienced art initiatives offer a meaningful manner to mix creativity with sustainability. Using recycled, upcycled, and herbal materials, artists can reduce their environmental results whilst producing lovely and galvanizing works of paintings. The tasks not only highlight the importance of environmental recognition but also exhibit that creative expression and ecological responsibility can go hand in hand. Whether you're an experienced artist or a newbie, eco-friendly art gives countless possibilities to create beauty sustainably and inspire others to do the same.
#EcoFriendlyArt#SustainableArt#RecycledMaterials#UpcycledCrafts#NaturalPigments#DIYProjects#GreenLiving#EnvironmentalArt
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Importance of Vitamin B12, Vitamin D, and Liver Function Tests in Dombivli

Liver Function Tests (LFTs) are a group of blood tests that are commonly performed to assess the health and function of the liver. The liver is a vital organ responsible for numerous metabolic functions, including detoxification, protein synthesis, and the production of biochemicals necessary for digestion.
Liver Function Test in Dombivli typically measure various enzymes, proteins, and substances in the blood that can indicate how well the liver is functioning. These tests may include:
Alanine transaminase (ALT) and Aspartate transaminase (AST): These enzymes are released into the bloodstream when liver cells are damaged. Elevated levels of ALT and AST may indicate liver injury or disease.
Alkaline phosphatase (ALP): ALP is an enzyme found in the liver, bile ducts, and bones. Elevated ALP levels may suggest liver or bone disease.
Bilirubin: Bilirubin is a waste product produced when the liver breaks down old red blood cells. High levels of bilirubin can indicate liver disease or problems with bile ducts.
Albumin and Total Protein: These tests measure the levels of proteins produced by the liver. Low levels may indicate liver damage or disease.
Prothrombin Time (PT) and International Normalized Ratio (INR): These tests measure how long it takes for blood to clot. Liver disease can affect blood clotting factors produced by the liver, leading to prolonged PT and increased INR.
Liver Function Tests are often performed as part of routine health screenings, to monitor liver function in individuals with known liver disease, or to diagnose liver conditions such as hepatitis, cirrhosis, or fatty liver disease.
It's important to note that while Liver Function Tests can provide valuable information about liver health, they are not diagnostic of specific liver conditions. Further testing, such as imaging studies or liver biopsy, may be necessary to confirm a diagnosis.
Liver Function Tests play a crucial role in assessing liver health and detecting potential liver problems early, allowing for timely intervention and management.
Are you feeling fatigued, experiencing muscle weakness, or noticing a lack of concentration? These could be signs of underlying health issues, and getting tested for essential vitamins and liver function can provide valuable insights into your well-being. At our clinic in Dombivli, we understand the importance of proactive healthcare, which is why we offer comprehensive Vitamin B12 tests, Vitamin D tests, and Liver Function tests.
When it comes to maintaining optimal health, knowledge is key. Our Vitamin B12 Test in Dombivli helps identify any deficiencies in this crucial nutrient. Vitamin B12 is essential for nerve function, red blood cell production, and DNA synthesis. Deficiencies can lead to fatigue, weakness, and neurological problems. With our precise testing methods, you can ensure your body is getting the necessary levels of Vitamin B12 for overall vitality.
Similarly, our Vitamin D Test in Dombivli is vital for assessing your body's Vitamin D levels. Known as the "sunshine vitamin," Vitamin D plays a crucial role in bone health, immune function, and mood regulation. Living in urban areas like Dombivli can sometimes limit sun exposure, leading to Vitamin D deficiencies. Our accurate tests provide insights into your Vitamin D status, allowing you to take appropriate steps to maintain optimal levels and support your overall health.
But it's not just about vitamins; liver function is equally important for overall well-being. Our Liver Function Test in Dombivli evaluates the health of your liver by measuring various enzymes and proteins in the blood. The liver performs essential functions like detoxification, metabolism, and nutrient storage. An unhealthy liver can lead to a range of problems, including fatigue, jaundice, and digestive issues. By regularly monitoring your liver function, you can take proactive steps to maintain liver health and prevent potential complications.
At our clinic, we prioritize your health and well-being. Our state-of-the-art facilities and experienced medical professionals ensure accurate results and personalized care. Whether you're experiencing symptoms or simply want to stay proactive about your health, our tests provide valuable insights that empower you to make informed decisions.
Booking a Vitamin B12 test, Vitamin D test, or Liver Function test in Dombivli is easy and convenient. Simply schedule an appointment at our clinic, and our friendly staff will guide you through the process. We understand that health concerns can be worrying, which is why we strive to make your testing experience comfortable and stress-free.
Investing in your health today can lead to a happier and more fulfilling tomorrow. Don't wait until symptoms arise; take control of your well-being with our comprehensive tests. Whether you're looking to optimize your vitamin levels or ensure your liver is functioning optimally, we're here to support you every step of the way.
Prioritize your health and schedule your Vitamin B12, Vitamin D, or Liver Function test in Dombivli today. Your body will thank you for it.
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Um, for POVs how about Noora? Or Noora/Fennec?? Or Fennec anything really. Also, those Tatooine constellation words. I’d LOVE to read those!!!!! I love your worldbuilding and am a HUGE sucker for stars. AST is 100% Star Wars, it reads like SW, feels like SW, and it just incredible. I hope you know how much joy it brings to so many people 🥹💙


ASK AND YE SHALL RECIEVE: IT'S NOORA TIME!
(this is also gonna be my last POV answer for this week; if you sent in an ask and didn't see a response, it's not because it won't be answered! i'm gonna be focusing on the next ast chapter this week, and will return to POV requests in a bit! thank you all so much for your responses -- you've all made my week!!)
in which noora puts the pieces together.
“Oh, Mother of Mountains,” Noora swore, sitting bolt upright. Fennec, who’d had an arm slung across Noora’s hips and her face tucked very prettily into the curve on Noora’s shoulder, let out an inarticulate groan.
“Sorry, dear,” said Noora, distracted. She stared off out the window, where the suns were rising over the Great Dune Sea. “It’s just – they’re fucking, aren’t they?”
Fennec made another inarticulate noise, obviously disgruntled, and managed to peel her face away from the bed. She’d fallen asleep without taking her braids out, which was how Noora knew Fennec really had been tired, last night, when she’d taken Noora into her bed instead of going back to Mos Eisley to visit Noora’s.
Not that Noora minded spending the night in Fennec’s bed – Fennec’s rooms were still pretty impersonal, even though she’d lived in them for months, but her bed was soft and her rooms were warm and the view was pretty good.
Fennec seemed to prefer Noora’s little house in the Quarter, though. She’d never said as much outright, but Noora could tell. She’d seen the little smell Fenn had gotten on her face, the other night, when she’d rummaged around for some clean clothes to wear and found that Noora’d bought a bunch of comfortable black clothes in Fenn’s size.
“Who’s fucking?” said Fennec, blinking blearily. Her braids were fuzzed with sleep and her cheek was red where it had been pressed against Noora’s shoulder.
Noora felt a little bad, now. Fennec rarely slept, but she’d been stone unconscious just a minute ago. Noora’d been awake for a while – the first light of the suns always woke her up, no matter how long she’d been up the night before – and had been lying very still, trying to prolong Fennec’s rest, when she had, unfortunately, fit the pieces of the holopuzzle together.
But Noora had put the pieces together, and if she didn’t tell Fennec about it, Noora thought that she might explode.
“Din and the boss,” Noora said. She watched Fennec’s expression expectantly. “Right?”
Fennec was a consummate professional. She’d always been that way. Her face gave nothing away.
Ah, Noora thought, looking at Fennec. But her eyes –
There was a flicker there, in the dark eyes that Noora loved so much.
Noora grinned. “Oh, good,” she said, happily.
Fennec raised an eyebrow.
“Oh, don’t look at me like that,” said Noora, leaning back against her bed, satisfaction making her lekku twitch. “That was bothering me.”
“What was bothering you?” Fennec asked, waking up a little. She took her arm off Noora’s hips and dragged it over her eyes, wiping away some of her sleep. Noora softened. Waking up in the same bed as Fennec might not surprise Noora some time in the future, but here, now, it was a surprise every time.
They made a pretty scene in bed together, Noora and Fennec. Noora hadn’t fallen into bed with Fennec for that reason – Noora liked to make pretty scenes, of course, because she’d been a dancer for most of her life and making things beautiful had been most of Noora’s job – but it was true all the same.
Noora was naked, still, wrapped in a bed sheet, and she knew how nice she looked hat way, her blue skin glowing in the early morning light, white tattoos curling over her lekku and her shoulders and her hips, the small of her back. Fennec had been a force of nature last night, relentless in the best way, and Noora’s inner thighs still bore those bruises. She was deliciously sore.
Fennec never took her clothes off, not all the way. She didn’t like exposing her prosthetics to open air. But she was beautiful too, all black hair and bright, clever eyes, and Noora liked the way they looked together.
Back to the point, though, Noora thought, because she knew that if she started to think about just how pretty Noora and Fenenc looked together, she and Fennec would lose track of the conversation entirely.
“Why Din and the boss have been acting so strangely,” Noora admitted, circling back to her original point. She stretched luxuriously and swept her lekku off her shoulders, rolling her shoulders. Fennec made an appreciative sound.
“Din always acts strangely,” Fennec muttered.
Noora rolled her eyes. That was true, a little. It wasn’t that Din – Din Djarin, Mando to most of Boba Fett’s court and Din only when the three of them, Noora and Fennec and Din, were having breakfast together – meant to be strange, but he kind of was. Noora’d never met anyone who managed to be both so fierce and so shy at the same time.
“He’s been stranger than usual,” Noora countered. And he had been. Din paced around the throne room now, when before he’d just leaned against the wall. He was snappish and withdrawn at breakfast, even when Noora’d ordered him some extra-strong red tea, and he hadn’t been getting a lot of sleep, the last few days.
Well, thought Noora. None of us have, not really. Not since the raid.
Noora could count on one hand how many nights she’d actually slept through, since the raid. She kept waking up in a jolt, expecting to find Gorga the Hutt himself in her bedroom, a chain in his hands, or worse – sometimes Noora woke up and thought she’d dreamed all of this, had dreamed Boba’s return to Tatooine and the warmth of Fennec’s hands, had dreamed up her freedom and her happiness and the careful life Noora’d been building ever since Boba shot Bib Fortuna and set Noora free. She woke up some times expecting to go and dance before Jabba again, praying to any spirits who’d still hear her that she wouldn’t fall into the rancor’s cage.
They were all worn thin, everyone who lived or worked at the palace. Din had reason to be tired, maybe. But his behavior in the throne room last night – the endless pacing, the looks he’d kept shooting the boss while the boss had been on his throne, kark, the way the boss had come up to Din when Noora’d pulled him off the floor and tried to settle him with a drink –
“Good for Din,” Noora murmured.
Fennec snorted.
“What?” Noora asked, arching an eyebrow. Her lekku twitched. “I assume you’ve known all along?”
“Not… all along,” Fennec conceded, her lips twitching up into a faint smile. “But I’ve known for a while, yeah. Djarin’s got a terrible sabacc face, and Boba pines when he’s away.”
“Oh, does he?” Noora asked, interested. “The boss? Pining?”
Boba Fett didn’t seem like the type to pine. Noora remembered him a little, from the old days. He had watched the dancers with Jabba a time or two. Boba Fett was a man who knew how to get what he wanted.
“It’s awful,” Fennec confirmed, smiling. “Not that Djarin’s any better.”
“No,” said Noora, smiling back. “I bet he’s just as bad.”
But then she remembered Din’s mood over the last few days – withdrawn, silent and strange, his kind face pinched with unhappiness even over scrambled junda bird eggs and bladeback bacon – and sobered.
“They weren’t fighting, were they?”
“I couldn’t say,” said Fennec, with just enough warning in her tone for Noora to leave it alone.
“It’s their business,” Noora admitted. But she rallied, brightening again, when she remembered how nervous the boss had sounded, last night, when he’d asked Din to come up to his rooms. “But I bet they’re reconciled now.”
Even though the boss’s rooms were only one floor above Fennec’s – and Din’s one floor below – everything in the palace was made from solid red sandstone. Noora would’ve have heard a bomb go off up there, let alone the boss and Din reconciling.
“I couldn’t say,” Fennec repeated. Her tone was a little sly, though. “But I could make an educated guess.”
Noora laughed. “Well,” she said. “Good.”
It was good. Noora was happy for them. She didn’t know if there was more to it than just sex or not – it was hard to tell with the boss, and Noora rather thought that if she asked Din outright, he might flee the system – but it was good that they were letting off some of their restlessness. It was good that they were taking care of each other.
“Mm,” Fennec agreed. She still hadn’t made a move to get out of bed, which was a little surprising, honestly; Fennec, like Noora, wasn’t one for a lazy morning in bed. Not when there was work to do, and there was always work to do here in Boba Fett’s palace. Noora had a bar to restock and a squadron of cleaning droids to marshal. She had a tapestry, finished just yesterday to hang over that awful scar behind Boba’s throne. She had a hundred things to do and a hundred more things to supervise, since Boba Fett was decently good at running a criminal enterprise but terrible at managing a palace.
But Fennec was warm beside her.
“Freykka,” Noora said, lightly. Fennec lifted an eyebrow again. “I know it’s their business, but, in your opinion, as the master of Boba Fett’s spies and his guards and honestly most of his empire – ” Fennec lifted her other eyebrow, obviously pleased “ – what are the chances that Din and the boss are gonna be awhile, before they get up?”
“Mm,” Fennec said again, reaching up to run one delicate finger down the length of one of Noora’s lekku, smiling when Noora shivered, her whole body bending towards the touch. Fennec leaned in closer. Her breath was warm against the curve of Noora’s cheek.
“I would say,” Fennec murmured, her hand falling again to Noora’s hip, “that there’s a pretty good chance they’re going to be a while. There’s no court this morning.”
“Good,” Noora murmured back, turning to catch Fennec’s mouth in a kiss. Fennec let her, which thrilled Noora every time. “If there’s no court, we’ll have to find some way to fill the time.”
Fennec’s hand left Noora’s hip. Skimmed across the top of her thigh. “I have a few ideas,” she said, and Noora laughed.
#ast asks#ast tag#if you're reading this going 'why am i hearing the classic billy eichner quote;'#'let's go lesbians!'#it's because you should be!#for real though i utterly adore noora#it's maybe conceited to love my ocs this much#but i do! i just love them!
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A Smart Guide to Primers: What to Use and Why
Perfect base makeup often involves a consistent skin tone and smooth finish. Layered between your moisturiser and foundation, primer is designed to do this by ‘filling in’ your skin’s pores to reduce the build up of oil and to create a more even surface on which foundation can sit. Primers are also frequented for their ability to ‘lock’ foundation in place, so you’re less likely to experience transfer throughout the day. You’ll notice they can come with other perks, such as a tint to mask discolouration, illuminating particles for a lasting glow, and nutrients to simultaneously heal and protect the skin’s external and internal layers.
Carol Mackie, Senior Global Artist for MAC says that while all skin types will benefit from primer use, oilier skin types in particular “are more prone to make up wearing off more quickly so a primer will prolong the wear of foundation.” The same goes for hotter climates, where primers are key to ensuring your foundation won’t slide with sweat.

TIP: Ensure sunscreen is applied underneath your primer and thoroughly absorbed – safety first!
Consider primer application prior to your foundation much like stretching ahead of a jog – skipping step one usually means problems for step two. Wearing a primer will allow your foundation to work to its full potential, however choosing any primer off the shelf could be remiss. When cooking, mixing oil with water simply doesn’t work. The liquids are different in build and remain separate even when spun together. The same principle can be seen for oil and water-based cosmetics. While hard to measure definitively, your safest bet is to marry like-for-like base products for the most even, long-lasting foundation finish.
TIP: Primer needn’t be applied across the whole face, says Mackie. For those with combination skin types, best apply primer along the oiliest areas of the face only, avoiding dry spots where primer isn’t necessary.
Make Up For Ever boasts a range of primers that can be layered, depending on your desired end result. The brand’s Makeup For Ever Step 1 Mattifying Primer is numbered one of eleven in this range, and is best worn alone as it doesn’t contain silicones. Instead, it contains silica that is a naturally occurring property that, like its synthetic sister silicone, is able to absorb moisture.
Other primer products that fit this bill include Too Faced’s Hangover Primer a lightweight primer that feels divine on the skin, MAC’s Prep + Prime Natural Radiance that contains illuminating vitamins E and C, and cruelty-free brand BECCA’s First Light Priming Filter. For a totally silicone and toxin-free option, try little-known brand Vapour Organic Beauty’s Status Soft Focus Skin Perfecting Primer, which is ideal for those keen on exploring an all-natural, water-based solution.
TIP: “Apply with a brush rather than your fingertips to avoid any natural oils in your fingers, and the brush will allow primer to glide on evenly!” Mackie suggests.
The same is often said for silicone-based products that act similarly to oils in that they are both stagnant. In other words, silicones and oils alike won’t penetrate the skin like water, but rather rest in our pores to create an even slate on which a foundation can sit and latch onto. These products work best for those with mature skin because such additives provide an exceptionally plump finish younger skins don’t need. Dimethicone, for example, is commonly used and acts as a conditioning solution for the skin, delivering a velvety, smooth finish while retaining water.

For the perfect everyday primer which hydrates the skin, helps foundation glide on smoothly, and increases wear (and works with a variety of different foundation formulas) you can’t go past Marc Jacobs’ Beauty Under(Cover) Perfecting Coconut Face Primer. Its smooth, lightweight, water-based formula works for all skintypes and won’t aggravate sensitive skin.
Smashbox PhotoFinish Foundation Primer and BareMinerals’ Prime Time Original Foundation Primer are transparent gels that glide on and leave an invisible, powdery-matte veil. La Mer’s The Hydrating Illuminator does a beautiful job at delivering to its name. Work it overtime as a cream highlighter on top of your foundation, too. Hourglass Mineral Veil Primer is a fantastic all-rounder primer that truly doesn’t budge and will fill you with confidence on a night out of dancing, it’s especially great for ultra oily skin!
Sisley has an exceptional track record of delivering effective skin and makeup products. The verdict is no different when it comes to their Sisley Instant Correct Color Correcting Primer. As one of two shades available, Just Lavender offsets dull pale skin and red undertones, while simultaneously softening fine lines. For a fraction of the cost, Rimmel’s Insta CC Primers are also worth a try and like Sisley’s, its liquid is creamy and blendable, unlike the thick, pigmented colour-correctors we’ve trialed in the past.
Napoleon Perdis’ Auto Pilot Brightening Skin Primer, housed in a distinguishable pink tube, is also a decent all-rounder that soaks into skin leaving a dewy, hydrated playing field on which to apply your foundation of choice. We found it worked well under a variety of foundation types. If a two-in-one primer-foundation product excites you, have a go of Dermalogica’s Skinperfect Primer SPF 30. It’s been a beauty cabinet staple for years, and works wonders on minimal make-up days. You’ll reap the benefits of a broad-spectrum protectant, long-lasting tint, and airbrushed finish in one.
TIP: Post-application, allow your primer to sit and soak into the skin before adding your foundation; a good 60 seconds should do the trick.
Shop This Post:
Makeup For Ever Step 1 Mattifying Primer
Too Faced’s Hangover Primer
MAC’s Prep + Prime Natural Radiance
BECCA’s First Light Priming Filter
Vapour Organic Beauty’s Status Soft Focus Skin Perfecting Primer
Marc Jacobs’ Beauty Under(Cover) Perfecting Coconut Face Primer
Smashbox PhotoFinish Foundation Primer
BareMinerals’ Prime Time Original Foundation Primer
La Mer’s The Hydrating Illuminator
Hourglass Mineral Veil Primer
Sisley Instant Correct Color Correcting Primer
Rimmel’s Insta CC Primers
Napoleon Perdis’ Auto Pilot Brightening Skin Primer
Dermalogica’s Skinperfect Primer SPF 30
Story by: Hannah Gay
Photography by: Evangeline Sarney
#makeup#primer#hannahg#expert#interviews#experts#interview#hourglass#rimmellondon#smashbox#marc jacobs#mac#mac cosmetics#too faced#becca#becca cosmetics#sisley#la mer#makeup forever
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Shared post Covid-19 USA
Copied from another group. I do not know who wrote this but it is worth sharing.
I am an ER MD in New Orleans. Class of 98. Every one of my colleagues has now seen several hundred Covid 19 patients and this is what I think I know.
The clinical course is predictable. 2-11 days after exposure (day 5 on average) flu-like symptoms start. Common are fever, headache, dry cough, myalgias(back pain), nausea without vomiting, abdominal discomfort with some diarrhea, loss of smell, anorexia, fatigue. Day 5 of symptoms- increased SOB, and bilateral viral pneumonia from direct viral damage to the lung parenchyma. Day 10- Cytokine storm leading to acute ARDS and multiorgan failure. You can literally watch it happen in a matter of hours. 81% mild symptoms, 14% severe symptoms requiring hospitalization, 5% critical. Patient presentation is varied. Patients are coming in hypoxic (even 75%) without dyspnea. I have seen Covid patients present with encephalopathy, renal failure from dehydration, DKA. I have seen the bilateral interstitial pneumonia on the Xray of the asymptomatic shoulder dislocation or on the CT’s of the (respiratory) asymptomatic polytrauma patient. Essentially if they are in my ER, they have it. Seen three positive flu swabs in 2 weeks and all three had Covid 19 as well. Somehow this ***** has told all other disease processes to get out of town. China reported 15% of cardiac involvement. I have seen covid 19 patients present with myocarditis, pericarditis, new-onset CHF and new-onset atrial fibrillation. I still order a troponin, but no cardiologist will treat no matter what the number in a suspected Covid 19 patient. Even our non-covid 19 STEMIs at all of our facilities are getting TPA in the ED and rescue PCI at 60 minutes only if TPA fails. Diagnostic CXR- bilateral interstitial pneumonia (anecdotally starts most often in the RLL so bilateral on CXR is not required). The hypoxia does not correlate with the CXR findings. Their lungs do not sound bad. Keep your stethoscope in your pocket and evaluate with your eyes and pulse ox. Labs- WBC low, Lymphocytes low, platelets lower than their normal, Procalcitonin normal in 95% CRP and Ferritin elevated most often. CPK, D-Dimer, LDH, Alk Phos/AST/ALT commonly elevated. Notice D-Dimer- I would be very careful about CT PE these patients for their hypoxia. The patients receiving IV contrast are going into renal failure and on the vent sooner. Basically, if you have bilateral pneumonia with normal to low WBC, lymphopenia, normal procalcitonin, elevated CRP and ferritin- you have covid-19 and do not need a nasal swab to tell you that. A ratio of absolute neutrophil count to absolute lymphocyte count greater than 3.5 may be the highest predictor of poor outcome. the UK is automatically intubating these patients for expected outcomes regardless of their clinical presentation. An elevated Interleukin-6 (IL6) is an indicator of their cytokine storm. If this is elevated watch these patients closely with both eyes. Other factors that appear to be predictive of poor outcomes are thrombocytopenia and LFTs 5x upper limit of normal.
Disposition I had never discharged multifocal pneumonia before. Now I personally do it 12-15 times a shift. 2 weeks ago we were admitting anyone who needed supplemental oxygen. Now we are discharging with oxygen if the patient is comfortable and oxygenating above 92% on the nasal cannula. We have contracted with a company that sends a paramedic to their home twice daily to check on them and record a pulse ox. We know many of these patients will bounce back but if it saves a bed for a day we have accomplished something. Obviously we are fearful some won’t make it back. We are a small community hospital. Our 22 bed ICU and now a 4-bed Endoscopy suite are all Covid 19. All of these patients are intubated except one. 75% of our floor beds have been courted into covid 19 wards and are full. We are averaging 4 rescue intubations a day on the floor. We now have 9 vented patients in our ER transferred down from the floor after intubation. Luckily we are part of a larger hospital group. Our main teaching hospital repurposed space to open 50 new Covid 19 ICU beds this past Sunday so these numbers are with significant decompression. Today those 50 beds are full. They are opening 30 more by Friday. But even with the “lockdown”, our AI models are expecting a 200-400% increase in covid 19 patients by 4/4/2020. Treatment Supportive worldwide 86% of covid 19 patients that go on a vent die. Seattle reporting 70%. Our hospital has had 5 deaths and one patient who was extubated. Extubation happens on day 10 per the Chinese and day 11 per Seattle. Plaquenil which has a weak ACE2 blockade doesn’t appear to be a savior of any kind in our patient population. Theoretically, it may have some prophylactic properties but so far it is difficult to see the benefit to our hospitalized patients, but we are using it and the studies will tell. With Plaquenil’s potential QT prolongation and liver-toxic effects (both particularly problematic in covid 19 patients), I am not longer selectively prescribing this medication as I stated in a previous post. We are also using Azithromycin, but are intermittently running out of IV. Do not give these patient’s standard sepsis fluid resuscitation. Be very judicious with the fluids as it hastens their respiratory decompensation. Outside the DKA and renal failure dehydration, leave them dry. Proning vented patients significantly helps oxygenation. Even self proning the ones on nasal cannula helps. Vent settings- Usual ARDS stuff, low volume, permissive hypercapnia, etc. Except for Peep of 5 will not do. Start at 14 and you may go up to 25 if needed. Do not use Bipap- it does not work well and is a significant exposure risk with high levels of aerosolized virus to you and your staff. Even after a cough or sneeze this virus can aerosolize up to 3 hours. The same goes for nebulizer treatments. Use MDI. you can give 8-10 puffs at one time of an albuterol MDI. Use only if wheezing which isn’t often with covid 19. If you have to give a nebulizer must be in a negative pressure room; and if you can, instruct the patient on how to start it after you leave the room. Do not use steroids, it makes this worse. Push out to your urgent care to stop their usual practice of steroid shots for their URI/bronchitis. We are currently out of Versed, Fentanyl, and intermittently Propofol. Get the dosing of Precedex and Nimbex back in your heads. One of my colleagues who is a 31 yo old female who graduated residency last May with no health problems and normal BMI is out with the symptoms and a SaO2 of 92%. She will be the first of many. I PPE best I have. I do wear a MaxAir PAPR the entire shift. I do not take it off to eat or drink during the shift. I undress in the garage and go straight to the shower. My wife and kids fled to her parents outside Hattiesburg. The stress and exposure at work coupled with the isolation at home is trying. But everyone is going through something right now. Everyone is scared; patients and employees. But we are the leaders of that emergency room. Be nice to your nurses and staff. Show by example how to tackle this crisis head-on. Good luck to us all.”
Unknown Writer Thank You
Everything Nursey
Shared post Covid-19 USA syndicated from https://everythingnursey.com/
Shared post Covid-19 USA syndicated from https://everythingnursey.com/
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Drugs that can be used to treat Multiple Sclerosis (MS), Part 2 of 3: Oral Disease-Modifying Agents (DMAs)
Dimethyl fumarate (Tecfidera)--DMF and its active metabolite, monomethyl fumarate (MMF), activate a cellular response pathway that responds to oxidative stress. Comes in 120 mg and 240 mg delayed-release capsules. Maintenance dose is 240 mg BID. Taken with food and/or aspirin to reduce flushing. May also cause GI upset and leukopenia/infection. There has been one case of fatal progressive multifocal leukoencephalopathy (PML) secondary to prolonged severe lymphopenia in Canada.
Fingolimod (Gilenya)--Sphingosine 1-Phosphate (S1P) Receptor Modulator that blocks WBCs' ability to leave lymph nodes, thereby decreased CNS inflammation. Dosage is 0.5 mg daily. May increase AST/ALT, especially in patients with hepatic impairment. Contraindicated in patients with most cardiac pathologies and/or CVA/TIA because it can cause HTN, AV block, bradycardia, and/or QT prolongation. There has been one reported case of (non-fatal) PML following the administration of Gilenya to a patient who had not previously received Tysabri (natalizumab), an MS drug associated with a higher risk of PML. Follow CBC, LFTs, EKG, ophthalmologic exam, VZV antibodies, and PFTs as indicated.
Teriflunomide (Aubagio)--A pyrimidine synthesis inhibitor that has antiproliferative and anti-inflammatory effects and may reduce the number of activated lymphocytes in the CNS. It is given 7 mg or 14 mg PO daily. It has the potential for significant hepatotoxicity, so monitor LFTs. It is teratogenic. May cause alopecia.
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Are Fat Reduction Diets the Particular Best
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Cycad toxicity
Because apparently dogs love eating random plants that are in no way edible!
Clinical signs - vomiting, diarrhoea, excessive salivation, lethargy are most common. Can also see icterus, melaena, coagulopathy, tremors, ataxia, and seizures.
Clinical pathology - Very high ALT and AST, high bilirubin seen typically. Also may see hypocholesterolaemia, hypoalbuminaemia, reduced urea, increased serum bile acids post-prandial, prolonged clotting times which are indicative of a low or non-functional liver. Thrombocytopenia and thrombocytopathy can also be seen.
Management steps:
Get rid of the bad stuff --> Induce emesis, gastric lavage, enema, activated charcoal PO
Support the liver --> N-acetyl cysteine, SAMe, ursodeoxycholic acid, silymarin, IV fluid therapy
Support the GIT (if bleeding present/suspected) --> omeprazole
Reduce nausea --> maropitant, ondansetron
Monitoring
PCV/TP, blood glucose, blood chemistry, electrolytes, faecal and urine analysis, neurological examinations, and TPRs are all important in this scenario.
Prognosis
This disease is often highly fatal as cycads are extremely toxic. It causes severe liver damage and may consequently lead to liver failure. Early treatment means the best outcome possible.
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TAGRISSO 80MG|OSIMERITINIB 80MG|MHP
DESCRIPTION

Tagrisso 80mg
A Tagrisso 80mg tablet is containing an active substance known as Osimeritinib, which is formerly known as Mereletinib.
Tagrisso 80mg is considered as third generation medicine, which is available in tablet form.
Tagrisso 80mg is an inevitable, selectively deviated epidermal growth factor receptor prohibitor, containing anti-cancer activity.
The pharmacological category of Tagrisso 80mg tablet is tyrosine kinase prohibitor.
INDICATION

Tagrisso 80mg
A Tagrisso 80mg tablet is widely indicated as first line therapy for advanced non-small cell lung cancer with EGFR mutation positive patients.
Tagrisso 80mg tablet is also used for the treatment of patients affected with advanced EGFR T792M mutation positive NSCLC, disease has advanced on or after the tyrosine kinase inhibitor treatment.
MECHANISM OF ACTION

Tagrisso 80mg
PROPERTIES
Ingredients : Bevacizumab
Strength : 100mg/4ml
Package : 400mg of Bevacizumab containing vial
ADME PROPERTIES
Absorption :
High plasma concentration time of Osimeritinib reaches within 6 hours
Distribution :
Volume of distribution 918L
Human Plasma protein bound to Osimeritinib is 95%
Metabolism :
The metabolism of Osimeritinib is occurs via oxidation.
The Two pharmacologically active metabolite of Osimeritinib are AZ7550 & AZ5104
Excretion :
The mean terminal half-life period 48 hours
Clearance value 14.3L/hr
68% of metabolite is excreted in feces; 14% through urine
2% of unchanged form of drug is eliminated
DOSAGE MANAGEMENT
The recommended dosage of Tagrisso 80mg tablets are, 80mg tablet should be taken as a single dose.
Tagrisso tablet should be administered with or without food.
If patient felt difficult to swallow the Tagrisso tablets as such, must disperse the tablet in 60ml of noncarbonated water and drink the solution immediately.
Tagrisso tablet do not break, crush or chew.
Interrupt the treatment during the conditions like;
Interstitial lung disease
QT prolongation
Symptomatic congestive heart failure
In pain management
Grade III or severe: discontinue the Tagrisso tablet for 3 weeks
Grade 0 to II: follow at 80mg or 40mg as a single dose
If no development in 3 weeks: Discontinue the therapy.
While co administration of Tagrisso with CYP3A4 inducers, the dosage of Tagrisso 80mg should be increased to 160mg as a single dose and followed by 80mg for 3 weeks after discontinuation of strong CYP3A4 inducers.
PRECAUTIONS

Interstitial lung disease:
Tagrisso 80mg
To avoid this problem, withheld or stop the Tagrisso 80mg tablets.
Keratitis:
Tagrisso 80mg
check the manifestation of keratitis regularly and provide supportive measures
Embryo fetal toxicity:
Tagrisso 80mg
Tagrisso 80mg tablet required in pregnancy period causes fetal damage.
QTc extension:
Do not concurrent use of Tagrisso 80mg with drug prolong the QTc
Cardiomyopathy:
Tagrisso 80mg
Periodic cardiac monitoring is assessed; in this condition stop the therapy.
SIDE EFFECTS
The most common adverse effects occurred during the therapy;
Cardiomyopathy, QT prolongation, Interstitial lung disease, Keratitis.
Other common side effect :
Diarrhea or constipation, Hyperglycemia, Hypomagnesemia, Hyponatremia, Elevation of AST & ALT, Stomatitis, Nausea, Vomiting, Rash, Nail toxicity, Pruritus, Dry skin, Headache, Cough, Dyspnea, Fatigue, Pyrexia, Loss of appetite, Respiratory tract infection, Lymphopenia, Thrombocytopenia, Anemia, Neutropenia.
PREGNANCY
Pregnancy category of Osimeritinib is not designate
While using Tagrisso 80mg tablet causes possible for fetal harm.
LACTATION
Milk feeding should not be taken during lactation period.
STORAGE
The Tagrisso 80mg tablet is, stored at 25°C.
Keep the tablet carton from moisture, heat and light.
MISSED DOSE
In case of missed dose, do not take the missed dose and follow the regular dosing schedule.
CONTACT US
PHONE NO:+91-9940472902 EMAIL :[email protected] WEBSITE :
https://millionpharma.com/osimeritinib-80mg.php
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