#polyether ionophore
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Potential of polyether ionophore compounds as antimalarials through inhibition on Plasmodium falciparum glutathione S-transferase by molecular docking studies
Image: Flickr Article published in J. Pharm. Pharmacogn. Res., vol. 10, no. 6, pp. 1139-1148, November-December 2022. DOI: https://doi.org/10.56499/jppres22.1478_10.6.1139 Alfian Wika Cahyono1,2, Icha Farihah Deniyati Faratisha1, Nabila Erina Erwan1,3, Rivo Yudhinata Brian Nugraha1,4, Ajeng Maharani Putri1,3, Loeki Enggar Fitri1,4* 1Malaria Research Group, Faculty of Medicine, Universitas…
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A polyether antibiotic is a fermentation chemical that facilitates the passive transport of ions across living cell membranes
Polyether antibiotics, also known as carboxyl ionophores, are a special type of antibiotic that belongs to the larger family of naturally occurring ionophores. The term "ionophore" was coined in 1967 to describe a molecule's ability to bind a metal ion and assist its transit through cellular membranes. Polyether ionophores' chemo-physiological properties have made them a helpful tool in the research of cation transport pathways, as well as the explanation for their biological activities.
Polyether Antibiotics are thought to have an effect on their target cells by altering the permeability of cellular membranes to cationic metal ions. Polyether ionophores have unique structural characteristics that are critical for their interaction with metal species. These traits include an alkyl backbone on the outside that confers lipophilic properties and an oxygen-rich interior cavity that can bind metal ions.
Read More @ https://medium.com/@poonamdcmi/polyether-antibiotics-are-fermentation-chemicals-that-assist-passive-transport-of-ions-across-2ef4597b6774
Source Link @ https://www.coherentmarketinsights.com/market-insight/polyether-antibiotics-market-2305
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Microorganisms, Vol. 8, Pages 271: Regulatory Patterns of Crp on Monensin Biosynthesis in Streptomyces cinnamonensis
Monensin, produced by Streptomyces cinnamonensis, is a polyether ionophore antibiotic widely used as a coccidiostat and a growth-promoting agent in agricultural industry. In this study, cyclic AMP receptor protein (Crp), the global transcription factor for regulation of monensin biosynthesis, was deciphered. The overexpression and antisense #RNA silencing of crp revealed that Crp plays a positive role in monensin biosynthesis. #RNA sequencing analysis indicated that Crp exhibited extensive regulatory effects on genes involved in both primary metabolic pathways and the monensin biosynthetic gene cluster (mon). The primary metabolic genes, including acs, pckA, accB, acdH, atoB, mutB, epi and ccr, which are pivotal in the biosynthesis of monensin precursors malonyl-CoA, methylmalonyl-CoA and ethylmalonyl-CoA, are transcriptionally upregulated by Crp. Furthermore, Crp upregulates the expression of most mon genes, including all PKS genes (monAI to monAVIII), tailoring genes (monBI-monBII-monCI, monD and monAX) and a pathway-specific regulatory gene (monRI). Enhanced precursor supply and the upregulated expression of mon cluser by Crp would allow the higher production of monensin in S. cinnamonensis. This study gives a more comprehensive understanding of the global regulator Crp and extends the knowledge of Crp regulatory mechanism in Streptomyces. http://bit.ly/2UXZRRI
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Polyether Antibiotics Market Outlook, Opportunity, Trends and Analysis, 2018–2026
Polyether ionophores antibiotics group consists of natural, biologically active substances produced by Streptomyces spp species. Polyether antibiotics have antifungal, antibacterial, antiviral, antiparasitic, and tumor cell cytotoxicity properties. Commercially, polyether ionophores antibiotics are majorly used to control coccidiosis. It is also used as growth promoters in cattle. There are several drugs in polyether antibiotics category such as Salinomycin and monensin. Commercially available polyether antibiotics include lasalocid (Avatec, Bovatec), monensin (Coban, Rumensin, and Coxidin), narasin (Monteban, Maxiban), maduramycin (Cygro), salinomycin (Bio-cox, Sacox), laidlomycin (Cattlyst), and semduramycin (Aviax).
Download PDF Brochure of Research Report @ https://www.coherentmarketinsights.com/insight/request-pdf/2305
Polyether Antibiotics Market Drivers
High demand for livestock and increased consumption of milk, beef, and other food products is expected to drive the global polyether antibiotics market growth. Increasing demand for pork and poultry meat along with increase in pig farming and poultry is expected to propel demand for polyether antibiotics. This is owing to the susceptibility of poultry animals and other animals to various types of infections and diseases. High demand for poultry meat is expected to support global polyether antibiotics market growth over the forecast period. For instance, according to according to the U.S. Department of Agriculture, the people in the U.S. are expected to eat an estimated 93 pounds of chicken per person in 2018.
According to a research presented at July 2018 Chicken Marketing Summit (survey was commissioned by the National Chicken Council), majority of consumers (89 percent of respondents) wanted more information about the chicken they buy and eat. Moreover, 35% of the respondents were concerned about proper use of antibiotics in poultry animals. It was found that consumers were likely to buy more chicken if there concerns were answered. These factors are expected to support the global polyether antibiotics market growth over the forecast period. Moreover, in a 2016 survey by the U.S. poultry veterinarians about important diseases, coccidiosis ranked first in importance followed by Necrotic enteritis (NE).
Request For Customization of Research Report @ https://www.coherentmarketinsights.com/insight/request-customization/2305
Polyether Antibiotics Market Regional Analysis
North America polyether antibiotics market is expected to hold a dominant position in the global polyether antibiotics market over the forecast period, owing to high presence of key players in the region along with several strategic mergers and acquisitions amongst the key players. For instance, in 2015, U.S.-based Eli Lilly and Company acquired Novartis Animal Health Inc. and strengthen its position of Eli Lilly and Company’s animal health business arm Elanco US, Inc. in the region. Asia Pacific is expected to witness highest growth over the forecast period owing to high consumption rate of poultry meat. For instance, according to The United States Department of Agriculture (USDA) Foreign Agricultural Service, chicken meat consumption in China in 2017 was approximately 11.6 million metric tons
Polyether Antibiotics Market Key Players
Key players operating in the global polyether antibiotics market include Zoetis, Inc., Elanco Animal Health Inc., Hester Biosciences Limited, Huvepharma AD, Ceva Sante Animale, and Dechra Pharmaceuticals PLC.
Polyether Antibiotics Market Taxonomy:
The global polyether antibiotics market is segmented on the basis of drug, application, and region
By Drug: Lasalocid, Monesin, Salinomycin, Narasin, Others,. By Application: Coccidiosis, Growth Promotion in Cattles, Others,. By Region: North America, Latin America, Europe, Asia Pacific, Middle East, Africa,.
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#Polyether Antibiotics Market#Polyether Antibiotics Market outlook#Polyether Antibiotics Market Trends
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Polyether Antibiotics Market Outlook to 2024: Top Companies in Market, Trends & Growth
Polyether ionophores antibiotics group consists of natural, biologically active substances produced by Streptomyces spp species. Polyether antibiotics have antifungal, antibacterial, antiviral, antiparasitic, and tumor cell cytotoxicity properties. Commercially, polyether ionophores antibiotics are majorly used to control coccidiosis. It is also used as growth promoters in cattle. There are several drugs in polyether antibiotics category such as Salinomycin and monensin. Commercially available polyether antibiotics include lasalocid (Avatec, Bovatec), monensin (Coban, Rumensin, and Coxidin), narasin (Monteban, Maxiban), maduramycin (Cygro), salinomycin (Bio-cox, Sacox), laidlomycin (Cattlyst), and semduramycin (Aviax).
Polyether Antibiotics Market Drivers
High demand for livestock and increased consumption of milk, beef, and other food products is expected to drive the global polyether antibiotics market growth. Increasing demand for pork and poultry meat along with increase in pig farming and poultry is expected to propel demand for polyether antibiotics. This is owing to the susceptibility of poultry animals and other animals to various types of infections and diseases. High demand for poultry meat is expected to support global polyether antibiotics market growth over the forecast period. For instance, according to according to the U.S. Department of Agriculture, the people in the U.S. are expected to eat an estimated 93 pounds of chicken per person in 2018.
Download the PDF brochure:
https://www.coherentmarketinsights.com/insight/request-pdf/2305
According to a research presented at July 2018 Chicken Marketing Summit (survey was commissioned by the National Chicken Council), majority of consumers (89 percent of respondents) wanted more information about the chicken they buy and eat. Moreover, 35% of the respondents were concerned about proper use of antibiotics in poultry animals. It was found that consumers were likely to buy more chicken if there concerns were answered. These factors are expected to support the global polyether antibiotics market growth over the forecast period. Moreover, in a 2016 survey by the U.S. poultry veterinarians about important diseases, coccidiosis ranked first in importance followed by Necrotic enteritis (NE). Increasing incidence of coccidiosis is further expected to support global polyether antibiotic market growth over the forecast period. According to a report by Federal Statistical Office in 2014, the U.S. was the largest producer of poultry meat with around 18% of the total meat produced worldwide. High production of poultry meat is expected to increase demand for polyether antibiotics in turn boosting the global polyether antibiotic market growth.
Some factors such as high administration of in-feed enzymes, stringent regulatory policies in the animal healthcare field, and increased use of substitute medicines including prebiotics are likely to restrain the global polyether antibiotic market growth over the forecast period.
Polyether Antibiotics Market Regional Analysis
North America polyether antibiotics market is expected to hold a dominant position in the global polyether antibiotics market over the forecast period, owing to high presence of key players in the region along with several strategic mergers and acquisitions amongst the key players. For instance, in 2015, U.S.-based Eli Lilly and Company acquired Novartis Animal Health Inc. and strengthen its position of Eli Lilly and Company’s animal health business arm Elanco US, Inc. in the region. Asia Pacific is expected to witness highest growth over the forecast period owing to high consumption rate of poultry meat. For instance, according to The United States Department of Agriculture (USDA) Foreign Agricultural Service, chicken meat consumption in China in 2017 was approximately 11.6 million metric tons
Polyether Antibiotics Market Key Players
Key players operating in the global polyether antibiotics market include Zoetis, Inc., Elanco Animal Health Inc., Hester Biosciences Limited, Huvepharma AD, Ceva Sante Animale, and Dechra Pharmaceuticals PLC.
Click To Reading More On Polyether Antibiotics Market
About Coherent Market Insights:
Also, Coherent Market Insights has a proprietary database of pipeline biologics and biosimilars, called PHASE-XS. This database provides analytical data in addition to the clinical information of ongoing trials for biologics and biosimilars. An amalgamation of more than 30 parameters, PHASE-XS helps biotechnology and pharmaceutical companies to analyze the market trend, competition, and market potential. For more information or to access this database, kindly click on the below link or contact at
https://www.coherentmarketinsights.com/phase-xs/
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Coherent Market Insights
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Seattle, WA 98154
Tel: +1-206-701-6702
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Polyether Antibiotics; Control Coccidiosis in Poultry and Boost Cattle Growth
Polyether antibiotics, also known as carboxyl polyethers, are a special type of antibiotics that have exceptional effectiveness against protozoa, bacteria, and viruses. Modification of cationic metal species is thought to impact cellular membrane permeability to their target cells. Polyether Antibiotics ionophores have specific structural characteristics that are critical for metal species interaction. Many polyether ionophores have powerful antibacterial properties, and a select number can target aggressive cells.
Read More @ https://www.coherentmarketinsights.com/market-insight/polyether-antibiotics-market-2305
Read More @ https://medium.com/@poonamdcmi/polyether-antibiotics-help-control-coccidiosis-in-poultry-and-promote-growth-in-cattle-e0157b660e5c
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Polyether Antibiotics Market 2019 Data Source, Methodology
Polyether ionophores antibiotics group consists of natural, biologically active substances produced by Streptomyces spp species. Polyether antibiotics have antifungal, antibacterial, antiviral, antiparasitic, and tumor cell cytotoxicity properties. Commercially, polyether ionophores antibiotics are majorly used to control coccidiosis. It is also used as growth promoters in cattle. There are several drugs in polyether antibiotics category such as Salinomycin and monensin. Commercially available polyether antibiotics include lasalocid (Avatec, Bovatec), monensin (Coban, Rumensin, and Coxidin), narasin (Monteban, Maxiban), maduramycin (Cygro), salinomycin (Bio-cox, Sacox), laidlomycin (Cattlyst), and semduramycin (Aviax).
Download the PDF brochure:
https://www.coherentmarketinsights.com/insight/request-pdf/2305
According to a research presented at July 2018 Chicken Marketing Summit (survey was commissioned by the National Chicken Council), majority of consumers (89 percent of respondents) wanted more information about the chicken they buy and eat. Moreover, 35% of the respondents were concerned about proper use of antibiotics in poultry animals. It was found that consumers were likely to buy more chicken if there concerns were answered. These factors are expected to support the global polyether antibiotics market growth over the forecast period. Moreover, in a 2016 survey by the U.S. poultry veterinarians about important diseases, coccidiosis ranked first in importance followed by Necrotic enteritis (NE). Increasing incidence of coccidiosis is further expected to support global polyether antibiotic market growth over the forecast period. According to a report by Federal Statistical Office in 2014, the U.S. was the largest producer of poultry meat with around 18% of the total meat produced worldwide. High production of poultry meat is expected to increase demand for polyether antibiotics in turn boosting the global polyether antibiotic market growth.
Some factors such as high administration of in-feed enzymes, stringent regulatory policies in the animal healthcare field, and increased use of substitute medicines including prebiotics are likely to restrain the global polyether antibiotic market growth over the forecast period.
Polyether Antibiotics Market Regional Analysis
North America polyether antibiotics market is expected to hold a dominant position in the global polyether antibiotics market over the forecast period, owing to high presence of key players in the region along with several strategic mergers and acquisitions amongst the key players. For instance, in 2015, U.S.-based Eli Lilly and Company acquired Novartis Animal Health Inc. and strengthen its position of Eli Lilly and Company’s animal health business arm Elanco US, Inc. in the region. Asia Pacific is expected to witness highest growth over the forecast period owing to high consumption rate of poultry meat. For instance, according to The United States Department of Agriculture (USDA) Foreign Agricultural Service, chicken meat consumption in China in 2017 was approximately 11.6 million metric tons
Polyether Antibiotics Market Key Players
Key players operating in the global polyether antibiotics market include Zoetis, Inc., Elanco Animal Health Inc., Hester Biosciences Limited, Huvepharma AD, Ceva Sante Animale, and Dechra Pharmaceuticals PLC.
Click To Reading More On Polyether Antibiotics Market
About Coherent Market Insights:
Also, Coherent Market Insights has a proprietary database of pipeline biologics and biosimilars, called PHASE-XS. This database provides analytical data in addition to the clinical information of ongoing trials for biologics and biosimilars. An amalgamation of more than 30 parameters, PHASE-XS helps biotechnology and pharmaceutical companies to analyze the market trend, competition, and market potential. For more information or to access this database, kindly click on the below link or contact at
https://www.coherentmarketinsights.com/phase-xs/
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