#pancreatic cancer blood test

[l3irdl3rain]

Merrill update under the cut, it’s long.

TLDR: she is very sick. Many of the things are treatable, but also she has cancer and I won’t put a 20 year old cat through chemo. So far she is showing minimal symptoms (sleeping more, less appetite). I’m hoping we can get the treatable things under control and we’ll have some good time left before the cancer really starts to affect her.

Radiologist said the “mass” that looked like it was on her heart is actually most likely just a bronchial cyst. I would need to go get a CT scan done to know for sure.

It’s not affecting her much yet, she just snores and when we were drawing blood she got a bad attitude and it made her wheezy. We can’t medicate for that yet bc the meds would upset her pancreatitis. So if we get the pancreatitis under control we can start medicating her for that.

Her bloodwork does show that she has some kind of cancer. I’m not going to chase after what kind it is because that would require a bone marrow test. Which is both painful and expensive. I’m not interested in putting a 20 year old cat through chemo, that would just be unfair to her, so ultimately it doesn’t make much of a difference what kind of cancer she actually has. It would just give me an idea of how quickly to expect things to progress. While that would be awesome to know, I don’t think it’s worth putting her through the testing.

We’re going to start by treating all the things we can and monitoring her for signs of any other issues. Definitely not what I was expecting to come from today. I figured there was a chance she’d have something small like hypertension or something, but definitely not for her to be falling apart all at once.

[tsuchinokoroyale]

Wait what, give us the cancer cell fun facts king

Sure thang 😎 Before I get into pancreatic cancer, let’s talk about lumps. One method of early tumor detection everyone should be periodically practicing is feeling yourself up for lumps. You should really get to know your testes if you got ‘em and it’s my scientific opinion that everyone should be feeling up their own chestes anyways, but it’s also good to do it on purpose to detect any abnormality as soon as possible.

What’s in a lump exactly? A healthy human body is a mix of many different cell types, and tumors are no different. I’m going to mostly correctly breakdown the various cell types as cells that do things/Epithelial cells, the in-betweeny/structurally important cells/Mesenchymal cells, and the blood cells where you got your cute lil red blood cells and immune cells. The interaction of all these cells forms something like an ecosystem, which we refer to as a microenvironment. Solid cancers arise from cells in tissues that lose the ability to die and/or gain the ability to keep dividing, so it makes sense that a lot of cell types present in the healthy microenvironment would be present in the tumor microenvironment/TME. However, the function of these cells have been found to be radically altered by the cancer cells in order to promote tumor growth and survival.

The pancreatic cancer lump is notable for two reasons: it is HARD and it is almost entirely made up of non-pancreatic cancer cells, with up to 90% of the tumor volume being non-cancer cells. A healthy pancreas is made up almost entirely of acinar cells which secrete digestive enzymes into the intestine, with some specialized regions for maintaining blood sugar levels. The pancreatic cancer TME on the other hand is an absolute circus. The lump is hard because the cancer has rewired certain mesenchymal cells to continuously churn out structural proteins, creating this densely fibrous netting which leads to drug permeability issues. There’s an influx of immune cells that should be performing anti-cancer duties but have instead been rewired to suppress immune responses. In order to prevent auto-immunity, the body’s own immune system targeting itself, there are various mechanisms by which the immune system will propagate a STOP response. The cancer cells adopt this process, secreting signals to override any productive immune response and push immune cells to suppress immune responses instead. As much as I’d love to get into the specifics and controversies of myCAFs, iCAFs, MDSCs, TAMs, Th1/2/17/regulatory CD4 family, and my poor downtrodden CD8 T cell babies, this post is already pretty long and I’m retired anyways 😮‍💨

in case anyone feels like reading the actual science version of this

[mit]

An implantable device could enable injection-free control of diabetes

The device contains encapsulated cells that produce insulin, plus a tiny oxygen-producing factory that keeps the cells healthy.

Anne Trafton | MIT News

One promising approach to treating Type 1 diabetes is implanting pancreatic islet cells that can produce insulin when needed, which can free patients from giving themselves frequent insulin injections. However, one major obstacle to this approach is that once the cells are implanted, they eventually run out of oxygen and stop producing insulin.

To overcome that hurdle, MIT engineers have designed a new implantable device that not only carries hundreds of thousands of insulin-producing islet cells, but also has its own on-board oxygen factory, which generates oxygen by splitting water vapor found in the body.

The researchers showed that when implanted into diabetic mice, this device could keep the mice’s blood glucose levels stable for at least a month. The researchers now hope to create a larger version of the device, about the size of a stick of chewing gum, that could eventually be tested in people with Type 1 diabetes.

“You can think of this as a living medical device that is made from human cells that secrete insulin, along with an electronic life support-system. We’re excited by the progress so far, and we really are optimistic that this technology could end up helping patients,” says Daniel Anderson, a professor in MIT’s Department of Chemical Engineering, a member of MIT’s Koch Institute for Integrative Cancer Research and Institute for Medical Engineering and Science (IMES), and the senior author of the study.

While the researchers’ main focus is on diabetes treatment, they say that this kind of device could also be adapted to treat other diseases that require repeated delivery of therapeutic proteins.

MIT Research Scientist Siddharth Krishnan is the lead author of the paper, which appears today in the Proceedings of the National Academy of Sciences. The research team also includes several other researchers from MIT, including Robert Langer, the David H. Koch Institute Professor at MIT and a member of the Koch Institute, as well as researchers from Boston Children’s Hospital.

Replacing injections

Most patients with Type 1 diabetes have to monitor their blood glucose levels carefully and inject themselves with insulin at least once a day. However, this process doesn’t replicate the body’s natural ability to control blood glucose levels.

“The vast majority of diabetics that are insulin-dependent are injecting themselves with insulin, and doing their very best, but they do not have healthy blood sugar levels,” Anderson says. “If you look at their blood sugar levels, even for people that are very dedicated to being careful, they just can’t match what a living pancreas can do.”

A better alternative would be to transplant cells that produce insulin whenever they detect surges in the patient’s blood glucose levels. Some diabetes patients have received transplanted islet cells from human cadavers, which can achieve long-term control of diabetes; however, these patients have to take immunosuppressive drugs to prevent their body from rejecting the implanted cells.

More recently, researchers have shown similar success with islet cells derived from stem cells, but patients who receive those cells also need to take immunosuppressive drugs.

Another possibility, which could prevent the need for immunosuppressive drugs, is to encapsulate the transplanted cells within a flexible device that protects the cells from the immune system. However, finding a reliable oxygen supply for these encapsulated cells has proven challenging.

Some experimental devices, including one that has been tested in clinical trials, feature an oxygen chamber that can supply the cells, but this chamber needs to be reloaded periodically. Other researchers have developed implants that include chemical reagents that can generate oxygen, but these also run out eventually.

The MIT team took a different approach that could potentially generate oxygen indefinitely, by splitting water. This is done using a proton-exchange membrane — a technology originally deployed to generate hydrogen in fuel cells — located within the device. This membrane can split water vapor (found abundantly in the body) into hydrogen, which diffuses harmlessly away, and oxygen, which goes into a storage chamber that feeds the islet cells through a thin, oxygen-permeable membrane.

A significant advantage of this approach is that it does not require any wires or batteries. Splitting this water vapor requires a small voltage (about 2 volts), which is generated using a phenomenon known as resonant inductive coupling. A tuned magnetic coil located outside the body transmits power to a small, flexible antenna within the device, allowing for wireless power transfer. It does require an external coil, which the researchers anticipate could be worn as a patch on the patient’s skin.

Drugs on demand

After building their device, which is about the size of a U.S. quarter, the researchers tested it in diabetic mice. One group of mice received the device with the oxygen-generating, water-splitting membrane, while the other received a device that contained islet cells without any supplemental oxygen. The devices were implanted just under the skin, in mice with fully functional immune systems.

The researchers found that mice implanted with the oxygen-generating device were able to maintain normal blood glucose levels, comparable to healthy animals. However, mice that received the nonoxygenated device became hyperglycemic (with elevated blood sugar) within about two weeks.

Typically when any kind of medical device is implanted in the body, attack by the immune system leads to a buildup of scar tissue called fibrosis, which can reduce the devices’ effectiveness. This kind of scar tissue did form around the implants used in this study, but the device’s success in controlling blood glucose levels suggests that insulin was still able to diffuse out of the device, and glucose into it.

This approach could also be used to deliver cells that produce other types of therapeutic proteins that need to be given over long periods of time. In this study, the researchers showed that the device could also keep alive cells that produce erythropoietin, a protein that stimulates red blood cell production.

“We’re optimistic that it will be possible to make living medical devices that can reside in the body and produce drugs as needed,” Anderson says. “There are a variety of diseases where patients need to take proteins exogenously, sometimes very frequently. If we can replace the need for infusions every other week with a single implant that can act for a long time, I think that could really help a lot of patients.”

The researchers now plan to adapt the device for testing in larger animals and eventually humans. For human use, they hope to develop an implant that would be about the size of a stick of chewing gum. They also plan to test whether the device can remain in the body for longer periods of time.

“The materials we’ve used are inherently stable and long-lived, so I think that kind of long-term operation is within the realm of possibility, and that’s what we’re working on,” Krishnan says.

“We are very excited about these findings, which we believe could provide a whole new way of someday treating diabetes and possibly other diseases,” Langer adds.

The research was funded by JDRF, the Leona M. and Harry B. Helmsley Charitable Trust, and the National Institute of Biomedical Imaging and Bioengineering at the National Institutes of Health.

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[eretzyisrael]

Good News From Israel

In the 18th Sep 22 edition of Israel’s good news, the highlights include:

Israeli scientists can detect pancreatic cancer with a blood test.

Israel is top of the global 

Israeli technology streams video simultaneously to millions of viewers.

An Israeli startup makes vegan meat from “used” vegetable oil seeds.

New York awarded $1 million to an Israeli energy company.

The movie Captain America 4 will feature an Israeli superhero.

A rare Judean “Freedom” coin has returned to the Jewish State.

Read More: Good News From Israel

Two prominent themes in this week's positive Israel newsletter are sustainable Israeli food technology and more life-changing innovations from the minds of Israelis. Following last week's super-food, this week we have Israeli lamb meat that never saw a lamb, vegan meat from seeds left over from the vegetable oil industry and dairy-free "milk" chocolate. Israeli tech produces fast-growing, disease-free avocados, and helps Brazil grow its most valuable crops in arid regions. All food can be cooked, using Israeli tech, on natural gas produced from organic waste, and washed down with water from the air in your electric vehicle. Meanwhile Israeli ingenuity is advancing cures for cancer, Parkinson's, and fatty liver disease. It is helping amputees use smart devices, improving the environment, building friendships with diverse communities and nations, and is top of the world for having the best digital quality of life. Israeli tech innovations are promoting Artificial Intelligence for good, streaming data to millions simultaneously, and purifying the air.

The photo is of Israel's Hula Lake, through which half a billion birds migrate, fed by Israeli farmers and Israeli environmental aquaculture.

[sodalite-lite]

found poem i made after reading Exposure. it can be read two ways.

[Text ID continued: The unhighlighted words read: Warning: Contains a chemical which can cause cancer. / A reaction aid in the production of polytetrafluorothylene and tetrafluoroethylene co-polymers. / The CAT Team findings support DuPont's position that the presence of PFOA at the low levels defected to date in drinking water in the Mid-Ohio Valley is not harmful. / Cumulative liver, kidney, and pancreatic changes can be induced in young rats by relatively low doses of PFOA. / Q: Is FC-143 harmful? A: The issue is concentration - how much and when. Animal studies with rats have demonstrated that it is slightly to moderately toxic. / We do know that it does not readily decompose, react, or break down. … It is expelled from the body slowly. / [bullet point] Never told Cattle Team and EPA about C8 in the stream. / We have not seen any negative effects on human health or the environment at the levels of exposure at which we operate. / We continued to increase our emissions into the river in spite of internal commitments to reduce or eliminate the release of this chemical into the community. / 14. Q: If the stuff is not harmful, why are you spending money to reduce air and water emissions? / [bullet point] C8 in the stream and we never told them. / A: … Even though the material has no known ill effects, it is our intent to minimize exposure which could cause concern associated with accumulation in the blood. / We remain that DuPont acted reasonably and responsibly at each stage in the long history of PFOA, placing a high priority on the safety of workers and community members. / Orally, it was claimed to be "slightly toxic"; with skin exposure, "slightly to moderately toxic"; and inhaled, it was "highly toxic". / There has been no adverse effect on employee health associated with FC-143 exposure. / There has been no adverse effect on employee health at these levels. / There is no evidence or data that demonstrates PFOA causes adverse human health effects. Many studies on the toxicology of PFOA lead us and others to conclude that the compound is safe for all segments of the population. / We are confident when we say that the facts, the scientific facts, demonstrate that the material is perfectly safe to use. / …indicate there's nothing to worry about. No human health effects. / Consensus is that the death was PFOA related. / There are a number of different exposure routes. …through inhalation. It can be absorbed through your skin to a limited amount, but inhalation is still by far more important. Then of course you could be exposed through ingestion, and that would be the drinking water. / Pose a risk to human health and the environment. / DuPont had always complied with all FDA regulations and standards regarding these products. / There is no evidence of adverse human health effects. / 20. Q: Is C8 carcinogenic? A: There is no evidence that C8 causes cancer in humans. Tests with laboratory animals demonstrated a slight increase in benign testicular tumors. / PFOA is not a human carcinogen and there are no known health effects associated with PFOA. In fact, the more we PFOA, … conclusions that PFOA is safe. / No known ill effects which could be attributed to those chemicals or C8 have been detected among employees in more than 20 years of experience with the products. / We've never had any adverse health effects from PFOA. / Persistence does not equal harm. Just because PFOA can cause kidney cancer doesn't mean that it caused Mrs. Barlett's kidney cancer.

The highlighted words read: Contains a chemical which can cause cancer. / low levels detected in the drinking water is not harmful / Cumulative liver, kidney, and pancreatic changes can be induced by relatively low doses of PFOA. / Is FC-143 harmful? studies have demonstrated that it is slightly to moderately toxic. / it does not readily decompose, react, or break down / negative effects on human health or environment at the levels at we operate. / continued to increase our emissions into the river / internal commitments to reduce or eliminate the release of this chemical in the community / never told them / known ill effects could cause concerns associated with accumulation in the blood / DuPont acted reasonably and responsibly, placing a high priority on the safety of workers and community members / Orally, "slightly toxic" / Skin exposure, "slightly to moderately toxic" / Inhaled, "highly toxic" / adverse effect on employee health associated with FC-143 exposure / no adverse health effect on employee health / no evidence or data PFOA causes adverse human health effects. PFOA is safe for all segments of the population. / No human health effects / Death was PFOA related / There are a number of different exposure routes. inhalation far more important. exposed through ingestion, the drinking water / Risk to human health and the environment / DuPont has complied with all FDA regulations and standards / No evidence adverse human health effects / Is C8 carcinogenic? / There is evidence that C8 causes cancer in humans. Tests demonstrated a slight increase in benign testicular tumors. / PFOA is not a human carcinogen, there are no known health effects. PFOA is safe. / known ill effects could be attributed to those chemicals or C8 among employees in 20 years of experience with the products. / We've had adverse health effects from PFOA. / Persistence does not equal harm. PFOA can cause kidney cancer. It caused Mrs. Barlett's kidney cancer. End Text ID.

[theodoretheninja]

So we had a coworker (there's only 8 of us so pretty close knit) call in sick about 3 weeks ago. He wound up in the hospital with blood clots in his legs. From there, they realized he needed back surgery. After further testing, they found he had pancreatic cancer. They found that out on Tuesday. He passed away today. He was late 40's, early 50's as far as I know. I'm not the praying type, but if you are, I'm sure his family would appreciate one.

Hug your loved ones and count your blessings. Life is short and you never know when it's your time.

Rest in peace, Brian. I didn't know you for a long time, but you were a good guy to know regardless.

[cornerstoneclinic]

Your Digestive Health Ally: A Comprehensive Guide to Gastroenterologists

The digestive system, a complex network of organs from your mouth to your rectum, plays a crucial role in processing food, absorbing nutrients, and eliminating waste. When things go wrong in this intricate system, it can lead to a range of uncomfortable and potentially debilitating conditions. This is where gastroenterologists, the guardians of your digestive health, come in.

This blog post delves into the world of gastroenterology, exploring what a gastroenterologist does, the conditions they treat, diagnostic procedures, treatment options, and how to find a Best Gastroenterologist Dubai.

Who is a Gastroenterologist?

A gastroenterologist is a specialized physician with expertise in diagnosing and treating diseases of the digestive system. This includes organs like the oesophagus, stomach, small intestine, large intestine (colon), rectum, liver, pancreas, and gallbladder. After completing medical school, gastroenterologists undergo several years of additional training, including an internal medicine residency and a gastroenterology fellowship.

What Conditions Do Gastroenterologists Treat?

Gastroenterologists manage a wide spectrum of digestive conditions, including:

Gastroesophageal Reflux Disease (GERD): Also known as heartburn, GERD is a condition where stomach acid backs up into the esophagus, causing discomfort and irritation.

Peptic Ulcers: These are sores that develop on the lining of the stomach or duodenum (the first part of the small intestine).

Irritable Bowel Syndrome (IBS): A chronic condition characterized by abdominal pain, cramping, bloating, diarrhea, or constipation.

Inflammatory Bowel Disease (IBD): This encompasses two chronic conditions, Crohn's disease and ulcerative colitis, that cause inflammation in the digestive tract.

Celiac Disease: An autoimmune disorder triggered by gluten, a protein found in wheat, barley, and rye.

Liver Disease: Gastroenterologists diagnose and treat various liver diseases like hepatitis, cirrhosis, and fatty liver disease.

Gallbladder Disease: This includes conditions like gallstones and inflammation of the gallbladder.

Pancreatitis: Inflammation of the pancreas, an organ behind the stomach that produces digestive enzymes and hormones.

Colorectal Cancer: Gastroenterologists play a crucial role in colorectal cancer screening, diagnosis, and treatment.

Diagnostic Tools Employed by Gastroenterologists

To diagnose digestive issues, gastroenterologists utilize a range of diagnostic tools, including:

Detailed Medical History and Physical Examination: A comprehensive review of your symptoms, medical history, and family history is crucial for initial assessment.

Blood Tests: Blood tests can reveal signs of infection, inflammation, or nutritional deficiencies.

Stool Tests: These tests can help diagnose infections, parasites, or hidden blood in the stool.

Imaging Techniques: X-rays, CT scans, MRIs, and ultrasounds can visualize the digestive organs and identify abnormalities.

Endoscopy: This procedure uses a thin, flexible tube with a camera to examine the inside of the digestive tract.

Upper Endoscopy: Examines the esophagus, stomach, and duodenum.

Colonoscopy: Examines the entire colon and rectum.

Biopsy: During endoscopy, a small tissue sample can be taken for further analysis under a microscope.

Treatment Options Offered by Gastroenterologists

Depending on the diagnosis, gastroenterologists offer a variety of treatment options, including:

Lifestyle Modifications: Dietary changes, managing stress, and getting enough sleep can significantly improve digestive health.

Medication: Medications are prescribed for various conditions, such as antacids for heartburn, antibiotics for infections, and anti-inflammatory drugs for IBD.

Endoscopic Procedures: Minimally invasive procedures like polyp removal or stricture dilation can be performed during endoscopy.

Surgery: In some cases, surgery might be necessary to treat certain conditions like gallstones or advanced cancers.

Finding the Best Gastroenterologist Dubai

If you're experiencing digestive problems, finding a qualified and Best Gastroenterologist Dubai is crucial. Here are some factors to consider:

Qualifications and Experience: Choose a board-certified gastroenterologist with extensive experience in treating your specific condition.

Hospital Affiliation: Consider the hospital or clinic where the gastroenterologist practices and ensure it has a good reputation and advanced facilities.

Communication Style: Look for a doctor who listens attentively to your concerns and explains things in a clear and understandable manner.

Location and Appointment Availability: Choose a gastroenterologist conveniently located and with appointment scheduling that suits your needs.

Insurance Coverage: Verify if the gastroenterologist accepts your health insurance plan to avoid out-of-pocket costs.

Patient Reviews: Reading online reviews from other patients can offer valuable insights into the doctor's bedside manner, communication skills, and overall patient experience.

Beyond Finding the Best: Building a Relationship with Your Gastroenterologist

Having an open and trusting relationship with your gastroenterologist is vital for optimal digestive health management. Here are some tips for building a strong patient-doctor relationship:

Be Prepared for Your Appointment: Make a list of your symptoms, medical history, and any questions you have for the doctor.

Be Honest and Open: Don't hesitate to discuss all your symptoms, even if they seem embarrassing. The more information you provide, the better your doctor can diagnose and treat your condition.

Ask Questions and Seek Clarification: Don't be afraid to ask questions and ensure you understand your diagnosis and treatment plan.

Follow Through with Treatment Recommendations: Adherence to your doctor's recommendations, whether it's medication, dietary changes, or lifestyle modifications, is crucial for successful treatment.

Schedule Regular Follow-up Appointments: Regular checkups allow your gastroenterologist to monitor your progress and adjust your treatment plan as needed.

The Importance of Preventive Care for Digestive Health

While gastroenterologists excel in treating digestive problems, prevention is always better than cure. Here are some tips for maintaining good digestive health:

Eat a Healthy Diet: Focus on a balanced diet rich in fruits, vegetables, whole grains, and lean protein.

Stay Hydrated: Drinking plenty of water throughout the day keeps your digestive system functioning smoothly.

Manage Stress: Chronic stress can wreak havoc on your digestive health. Practice stress-management techniques like yoga, meditation, or deep breathing.

Maintain a Healthy Weight: Being overweight or obese can increase your risk of certain digestive disorders.

Limit Alcohol and Smoking: Excessive alcohol consumption and smoking can irritate the digestive tract and contribute to digestive problems.

Get Regular Exercise: Regular physical activity can improve gut health and overall well-being.

Schedule Regular Screenings: Regular screenings for conditions like colorectal cancer are crucial for early detection and treatment.

The Future of Gastroenterology: Innovations for a Healthier Digestive System

The field of gastroenterology is constantly evolving, with exciting new technologies and treatment options emerging. Here's a glimpse into what the future might hold:

Advanced Imaging Techniques: Enhanced imaging technologies like capsule endoscopy and stool DNA testing might revolutionize diagnosis.

Personalized Medicine: Understanding individual gut microbiomes could pave the way for personalized treatment plans for digestive disorders.

Minimally Invasive Procedures: Advancements in endoscopic techniques and robotic surgery might lead to less invasive and more precise procedures.

Microbial Therapy: Research on the gut microbiome suggests potential for using probiotics and fecal microbiota transplants to treat digestive diseases.

Investing in Your Digestive Health: A Partnership with Your Gastroenterologist

Digestive health is a cornerstone of overall well-being. By prioritizing preventive care, finding a qualified Best Gastroenterologist Dubai, and building a strong patient-doctor relationship, you can navigate any digestive challenges effectively. Remember, open communication, adherence to treatment plans, and a commitment to a healthy lifestyle are your allies in maintaining a healthy digestive system. Cornerstone Clinic is also designed for everyday family health from leading UK Family Doctors to dentist to cosmetic surgeons to vascular treatments. To get the best out of our team, it’s important to discuss your needs with our practitioners so a program can be designed for your schedule especially for our longevity and rejuvenation programs. For example, many of our families will send children to the dentist, whilst mum has a botox and dad is receiving a health check at the same time.

[jdrsandeep]

Understanding Pancreatic Cancer: A Closer Look

Pancreatic cancer is one of the most challenging forms of cancer, often diagnosed at an advanced stage due to its subtle and vague symptoms. At Abdominal Cancer Trust, our mission is to provide comprehensive support, raise awareness, and fund innovative research to combat this formidable disease.

What is Pancreatic Cancer?

The pancreas, a crucial organ situated behind the stomach, plays a vital role in digestion and blood sugar regulation. Pancreatic cancer occurs when cells in the pancreas grow uncontrollably, forming a malignant tumor. There are two main types: exocrine tumors, which are more common and start in the ducts that carry pancreatic juices, and endocrine tumors, which originate in the hormone-producing cells.

Symptoms and Risk Factors

Early detection of pancreatic cancer is notoriously difficult because symptoms often mimic other conditions. Common signs include jaundice (yellowing of the skin and eyes), unexplained weight loss, persistent abdominal pain, and digestive issues. Risk factors include a family history of the disease, smoking, chronic pancreatitis, obesity, and diabetes.

The Importance of Early Detection

Given the aggressive nature of pancreatic cancer, early detection significantly improves the chances of successful treatment. At Abdominal Cancer Trust, we advocate for regular medical check-ups and awareness of family medical history. Advanced diagnostic tools and genetic testing are essential in identifying the disease in its early stages.

How Abdominal Cancer Trust Supports You

We are committed to offering emotional and practical support to patients and their families. Our resources include educational materials, support groups, and financial assistance programs to ease the burden during treatment. Additionally, we fund cutting-edge research aimed at improving diagnostic techniques and developing more effective therapies.

Join Our Fight

Pancreatic cancer is a daunting adversary, but with collective effort, we can make strides toward better outcomes. Support the Abdominal Cancer Trust by participating in our events, making a donation, or volunteering your time. Together, we can bring hope and a brighter future to those affected by pancreatic cancer.

For more information and resources, visit our website or contact us directly. At Abdominal Cancer Trust, we are here to fight alongside you.

For More Info: what is abdominal cancer

[drkamath]

Best Pancreatic And Periampullary Cancer in Banashankari Bangalore — Dr. Anil Kamath

In the fight against pancreatic and periampullary cancers, choosing the right specialist is crucial for achieving the best possible outcomes. In Banashankari, Bangalore, Dr. Anil Kamath is recognized as a leading expert in this field, offering state-of-the-art treatment and compassionate care for patients facing these challenging cancers.

About Dr. Anil Kamath

Dr. Anil Kamath is a distinguished surgical oncologist with extensive experience in treating a variety of cancers, particularly those affecting the gastrointestinal system. With a focus on pancreatic and periampullary cancers, Dr. Kamath has established himself as a trusted name in oncology, known for his skill, dedication, and patient-centric approach.

Understanding Pancreatic and Periampullary Cancers

Pancreatic cancer originates in the tissues of the pancreas, an organ that plays a vital role in digestion and blood sugar regulation. Periampullary cancer refers to tumors that arise in the region where the bile duct and pancreatic duct join and empty into the small intestine. Both types of cancer can be aggressive and are often diagnosed at an advanced stage due to subtle early symptoms.

Why Choose Dr. Anil Kamath for Treatment?

Specialized Expertise: Dr. Kamath’s extensive training and experience in oncology make him exceptionally qualified to handle complex cases of pancreatic and periampullary cancers. His deep understanding of these diseases enables him to devise effective and individualized treatment strategies.

Comprehensive Evaluation: Dr. Kamath conducts thorough evaluations to determine the most appropriate treatment plan for each patient. This includes advanced diagnostic techniques such as imaging studies, biopsies, and genetic testing to accurately assess the cancer’s stage and spread.

Cutting-Edge Surgical Techniques: Surgery is often a critical component in the treatment of pancreatic and periampullary cancers. Dr. Kamath is proficient in the latest surgical techniques, including minimally invasive procedures and the Whipple procedure, which is a complex operation aimed at removing tumors in the pancreatic head.

Multidisciplinary Approach: Dr. Kamath works closely with a team of specialists, including medical oncologists, radiologists, and nutritionists, to provide holistic care. This collaborative approach ensures that all aspects of the patient’s health are addressed, enhancing the effectiveness of the treatment plan.

Personalized Care: Recognizing that each patient’s journey is unique, Dr. Kamath tailors his treatment plans to meet individual needs. He takes the time to explain the diagnosis, treatment options, and potential outcomes, ensuring that patients and their families are well-informed and involved in decision-making.

Post-Treatment Support: Recovery and post-treatment care are crucial for improving quality of life and long-term outcomes. Dr. Kamath offers comprehensive follow-up care, including monitoring for recurrence, managing side effects, and providing nutritional and psychological support.

State-of-the-Art Facilities in Banashankari

Dr. Kamath practices at some of the premier hospitals in Banashankari, Bangalore, which are equipped with advanced medical technologies and facilities. These hospitals provide an optimal environment for comprehensive cancer care, from diagnosis to treatment and follow-up.

Patient Testimonials

Patients treated by Dr. Kamath consistently praise his professionalism, compassion, and the successful outcomes of their treatments. Many have shared their experiences of recovery and improved quality of life, attributing their positive journeys to Dr. Kamath’s expertise and empathetic care.

Conclusion

For those seeking the best treatment for pancreatic and periampullary cancers in Banashankari, Bangalore, Dr. Anil Kamath offers unparalleled expertise and compassionate care. His commitment to individualized treatment, advanced surgical techniques, and comprehensive support ensures that patients receive the highest standard of care. Trust Dr. Kamath to guide you through your cancer treatment journey with skill and compassion.

[cancerspecialistindore]

Who is the Leading Cancer Surgeon in Indore for Advanced Treatment?

Introduction 

If you are looking for  the experienced cancer surgeon in Indore, then look no further than Dr. Suyash Agrawal is the top expert to consider. Renowned for his exceptional skills and compassionate care, Dr. Agrawal specializes in a wide range of cancer surgeries, including breast, gastrointestinal, and head and neck cancers. His use of advanced surgical techniques and personalized treatment plans ensures best results possible for his patients. With a commitment to continuous learning and staying updated on the latest advancements in oncology, Dr. Suyash Agrawal provides the highest quality care, making him the go-to choice for cancer treatment in Indore.

What types of cancer surgeries does the surgeon specialize in?

The Dr. Suyash Agrawal  as the top cancer surgeon in Indore specializes in the following types of cancer surgeries:

Breast Cancer Surgery: Lumpectomy, mastectomy, sentinel lymph node biopsy, axillary lymph node dissection.

Gastrointestinal Cancer Surgery: Colorectal surgery, gastric surgery, pancreatic surgery, liver resection.

Thoracic Cancer Surgery: Lung cancer surgery, esophagectomy.

Head and Neck Cancer Surgery: Laryngectomy, pharyngectomy, neck dissection.

Gynecologic Cancer Surgery: Hysterectomy, oophorectomy, cytoreductive surgery.

Urologic Cancer Surgery: Prostatectomy, nephrectomy, cystectomy.

Dermatologic Cancer Surgery: Mohs surgery, wide local excision.

Orthopedic Cancer Surgery: Limb-sparing surgery, amputation.

Neurosurgery: Craniotomy, spinal tumor surgery.

What diagnostic tests and imaging services are available for cancer detection?

Here are seven diagnostic tests and imaging services commonly available for cancer detection, in the context of Dr. Suyash Agrawal, a cancer surgeon in Indore:

Mammography:

Uses X-rays to examine breast tissue for signs of breast cancer, typically recommended for women over 40 or those at high risk.

Colonoscopy:

Involves inserting a flexible tube with a camera into the colon to detect colorectal cancer or precancerous polyps.

Pap Smear (Pap Test):

Screens for cervical cancer by collecting cells from the cervix to examine for abnormalities.

Computed Tomography (CT) Scan:

Provides detailed cross-sectional images of the body to detect abnormalities or tumors in various organs.

Prostate-Specific Antigen (PSA) Test:

Measures the level of PSA in the blood, which may indicate prostate cancer or other prostate-related issues.

MRI (Magnetic Resonance Imaging):

Produces detailed images of soft tissues, organs, and bones, helpful in detecting tumors, especially in the brain, spine, and musculoskeletal system.

Biopsy:

Involves removing a small sample of tissue for examination under a microscope to confirm the presence of cancer cells.

These diagnostic tests and imaging services play a crucial role in the early detection, diagnosis, and treatment planning for various types of cancer.

How is a treatment plan developed after diagnosis?

After diagnosis by Dr. Suyash Agrawal, a cancer surgeon in Indore, a personalized treatment plan is meticulously developed. Dr. Agrawal conducts a thorough assessment of the patient’s medical history, diagnostic tests, and imaging results. He interacts closely with a multidisciplinary group of radiologists, oncologists, and other specialists to formulate the most effective treatment strategy. This may include surgery, chemotherapy, radiation therapy, immunotherapy, or a combination of these modalities tailored to the specific type and stage of cancer. Throughout the process, Dr. Agrawal prioritizes clear communication with the patient, ensuring they understand their options and feel supported every step of the way.

What are the success rates of Dr. Suyash Agrawal as the cancer Surgeon in Indore?

The success rates of cancer surgeries performed by Dr. Suyash Agrawal is consistently high, reflecting his proficiency and dedication to achieving optimal outcomes for his patients and making him the best cancer surgeon in Indore. While specific success rates may vary depending on the type and stage of cancer, Dr. Agrawal’s expertise ensures that patients receive the best possible surgical care with a focus on positive results and improved quality of life.

Conclusion

In conclusion,Dr. Suyash Agrawal is a trusted cancer surgeon in Indore who goes above and beyond for his patients. His commitment to providing patients the best treatment possible appears in every aspect of his job. Thanks to his knowledge and caring style, Dr. Agrawal makes sure every patient receives care that is specific to their needs. Patients may feel confident that they are in good hands with Dr. Suyash Agrawal, as he dedicates his life to enhancing patient outcomes and providing them with support during their cancer journey.Dr. Suyash Agrawal’s dedication to improving outcomes and enhancing the quality of life for cancer patients makes him a trusted and respected figure in the medical community of Indore.

[colonoscopycostsingapore]

Pancreatic Cancer in Singapore: Navigating a Complex Diagnosis

Pancreatic cancer, a malignancy arising from the pancreas, presents a significant health concern in Singapore. Despite not being the most common cancer, it ranks as the 4th most common cause of cancer death in women and the 5th in men https://www.ardenjrsurgery.com.sg/pancreatic-cancer-singapore . This blog post delves into pancreatic cancer in Singapore, exploring risk factors, symptoms, diagnosis, treatment options, and available resources.

Understanding Pancreatic Cancer in Singapore

The pancreas, a gland located behind the stomach, plays a crucial role in digestion and blood sugar regulation. Pancreatic cancer disrupts these functions, leading to a range of health complications. While the exact causes remain unknown, several factors contribute to its development.

Risk Factors for Pancreatic Cancer

Being aware of risk factors empowers you to make informed lifestyle choices and prioritize early detection:

Age: The risk of pancreatic cancer increases with age, particularly above 65.

Smoking: Smoking is a significant risk factor, damaging pancreatic cells.

Diabetes: Having type 2 diabetes can elevate the risk of pancreatic cancer.

Obesity: Excess weight increases the risk of developing pancreatic cancer.

Chronic Pancreatitis: Long-term inflammation of the pancreas can increase cancer risk.

Family History: A family history of pancreatic cancer suggests a potential genetic predisposition.

Diet: A diet low in fruits and vegetables and high in red meat may contribute to pancreatic cancer risk.

Symptoms of Pancreatic Cancer

Pancreatic cancer is often dubbed a "silent killer" due to its vague and non-specific symptoms that may appear in later stages. Here's what to watch out for:

Abdominal pain: This can be a constant dull ache or a sharp, gnawing pain in the upper abdomen that radiates to the back.

Unexplained weight loss: You may experience weight loss even with normal eating habits.

Jaundice: Yellowing of the skin and whites of the eyes occurs when bile ducts get blocked.

Loss of appetite: You may feel full quickly or have no desire to eat.

Nausea and vomiting: These can be persistent and may include blood.

New-onset diabetes: If you haven't had diabetes before, pancreatic cancer can trigger its development.

Fatigue: You may experience constant tiredness and a lack of energy.

Diagnosis of Pancreatic Cancer in Singapore

Early diagnosis is crucial for successful treatment. If you experience any of these symptoms, consult a doctor immediately. Diagnosis may involve a combination of tests:

Blood tests: These can check for abnormalities in liver function and tumor markers.

Imaging tests: CT scans, MRI scans, and PET scans can visualize the pancreas and detect tumors.

Endoscopic ultrasound: A thin, flexible tube with a camera is inserted through the mouth or rectum to examine the pancreas closely.

Biopsy: A tissue sample is collected during endoscopy or with a needle to confirm the presence of cancer cells.

Treatment Options for Pancreatic Cancer in Singapore

The course of treatment depends on the stage and type of pancreatic cancer. Here's an overview of the common treatment options available in Singapore:

Surgery: The Whipple procedure, a complex surgery, is performed for early-stage, localized pancreatic cancer. It involves removing the head of the pancreas, part of the small intestine, and the bile duct.

Chemotherapy: Powerful drugs are used to kill cancer cells and shrink tumors. It can be administered before or after surgery or as a standalone treatment for advanced stages.

Radiation Therapy: High-energy radiation beams target and destroy cancer cells. Radiation therapy may be used before or after surgery, or in combination with chemotherapy.

Palliative care: For advanced stages where a cure is not possible, palliative care focuses on managing symptoms and improving quality of life.

Living with Pancreatic Cancer

Following treatment, regular follow-up appointments with your doctor are essential to monitor for recurrence. Depending on the type of treatment received, dietary modifications and pain management strategies may be recommended to improve your quality of life.

Singapore’s Healthcare System and Pancreatic Cancer

Singapore's advanced healthcare system offers hope. Several public and private hospitals have highly skilled oncologists specializing in pancreatic cancer treatment. These facilities provide access to cutting-edge technologies and comprehensive treatment plans.

Living Beyond Pancreatic Cancer: Hope and Support in Singapore

While a pancreatic cancer diagnosis can be life-altering, Singapore offers a supportive environment for navigating this challenging journey. Here's how you can access resources and build a strong support system:

Empowering Yourself with Knowledge

Singapore Cancer Society (SCS): The SCS website [visit website] provides a wealth of information on pancreatic cancer, treatment options, and coping strategies.

National Cancer Centre Singapore (NCCS): The NCCS patient education library [visit website] offers downloadable resources and educational materials on pancreatic cancer.

Connecting with Others

Support Groups: Joining a support group allows you to connect with others facing similar challenges. The SCS and NCCS facilitate support groups specifically for pancreatic cancer patients and their families.

Online communities: Online forums and social media groups connect you with a wider community of patients and caregivers for sharing experiences and emotional support.

Maintaining Well-being

Nutrition: A registered dietitian can help develop a personalized eating plan to manage weight loss, improve digestion, and address any dietary restrictions caused by treatment.

Pain Management: Your doctor can recommend pain medication and strategies like physical therapy or massage therapy to manage pain associated with pancreatic cancer.

Mental Health Support: Coping with a serious illness can take a toll on mental well-being. Consider seeking counseling or joining support groups focused on emotional well-being during cancer treatment.

Looking Towards the Future

Living with pancreatic cancer requires a multi-pronged approach. By prioritizing medical care, connecting with support systems, and focusing on well-being, you can manage the challenges and improve your quality of life.

Remember: Early detection is paramount. If you experience any potential symptoms, don't hesitate to consult a doctor. With advancements in treatment modalities and Singapore's robust healthcare system, there is hope for a positive outcome.

Disclaimer: This blog post provides general information only and should not be considered a substitute for professional medical advice. Always consult your doctor for personalized guidance on pancreatic cancer diagnosis, treatment, and management.

[patient-education]

New and Updated Topics

The Patient Education Institute has published, reviewed or updated 82 titles in Q1 and Q2 2024.

Aid Tools for Older Adults English Amputation of the Leg English Anal Cancer English Anterior Cruciate Ligament Repair - ACL Repair English Aplastic Anemia English Bile Duct Diseases and Problems English Birth Control - Contraception (Arabic) Arabic Blood and Blood Disorders English Bronchitis English Building and Keeping Healthy Habits English Cancer Clinical Trials English Cannabis English Cardiac Catheterization - Coronary Angiography English Carotid Endarterectomy English Cerebral Palsy English Cerebral Palsy - Pediatrics English Cervix Disorders (Arabic) Arabic Changes as We Get Older English Cholecystectomy - Open and Laparoscopic English Common Accidents Among Older Adults English COVID-19 - Coronavirus English COVID-19 - Coronavirus (Arabic) Arabic COVID-19 - Coronavirus (Spanish) Spanish De Quervain's Tendonitis (Arabic) Arabic Diabetes - Introduction English Ectopic Pregnancy English Electroconvulsive Therapy - ECT (Arabic) Arabic Encephalitis English Fun Ways to Make Your Retirement Better English Gallstones English Game Addiction in Older Adults English Gastrointestinal Bleeding English H1N1 Influenza English Health Problems in Pregnancy English Hearing Loss English HIV/AIDS and Infections English HIV/AIDS and Pregnancy English Hysteroscopy English Influenza - Flu English Influenza - Pediatrics English Inguinal Hernia Repair - Pediatrics (Arabic) Arabic Iron Overload - Hemochromatosis (Arabic) Arabic IVP - Intravenous Pyelogram English Keeping a Positive Mindset English Keeping Your Retirement Money Safe from Crimes English Leukemia English Living with Congestive Heart Failure (Arabic) Arabic Long-Term Care Insurance English Making Your Body's Immune System Stronger English Midlife Crises and Transitions English Moles English Mumps English Newborn Screening English Open Shoulder Surgery English Organizing Your Medications English Palliative Care and Hospice Care English Pancreatitis English Pediatric Post-Operative Instructions English Port Catheter Insertions (Arabic) Arabic Preventing Strokes English Preventing Trips and Falls English Pulmonary Fibrosis English Reading Lab Results English Reporting and Preventing Elder Abuse English Sexuality and Aging English Shoulder Replacement English Sjogren's Syndrome English Stellate Block (Arabic) Arabic Suicide in Older Adults English The A1C Test English The FODMAP Diet for Digestive Health English Thoracotomy English Tracheotomy or Tracheostomy (Arabic) Arabic Transient Ischemic Attack - TIA English Understanding Medicare English Upper GI Endoscopy English Upper GI Endoscopy and Colonoscopy English Viagra - Sildenafil English Warfarin - Introduction for New Users English Warfarin - Introduction for New Users - Pediatrics English Warfarin - Review for Current Users English What to Expect When You Retire English

[industryforecastnews]

In Vitro Diagnostics Market Size To Reach $101.58 Billion By 2030

In Vitro Diagnostic Market Growth & Trends

The global in vitro diagnostics market size is expected to reach USD 101.58 billion by 2030, according to a new report by Grand View Research, Inc. It is estimated to register a CAGR of 4.4% over the forecast period driven by the increasing geriatric population, COVID-19 pandemic, and technological advancements in diagnostics that are supporting its adoption. Technological advancements in terms of portability, accuracy, and cost-effectiveness are projected to be one of the high-impact rendering drivers. Technological advancements were further accelerated by the launch of COVID-19 IVD diagnostics and enhanced the adoption of instruments and consumables for technologies, such as PCR. Competitors in the market are increasingly adopting agreement and partnership strategies to maintain a constant flow of business for manufacturers & diagnostics for users.

These agreements are also a result of the harsh price containment strategies for government laboratories, which lowers the price in government settings. For instance, in April 2021, the Italian subsidiary of Seegene, Inc. received a USD 108.25 million tenders for public procurement for the supply of extraction reagents, as well as 7.15 million SARS-CoV-2 diagnostic tests. However, it increases the multiparty nature and complexity of the supply chain. The high prevalence of cancer and Cardiovascular Diseases (CVDs) globally is anticipated to drive diagnostic innovation to facilitate early diagnosis and meet the constantly evolving needs of consumers. Novel technologies, such as plasmonic PCR, are anticipated to commercially enter the market during the forecast period, influencing the business of existing products adversely.

Technological advancements in terms of accuracy, portability, and cost-effectiveness are expected to be one of the high-impact rendering drivers of this market. Introduction of novel and highly accurate clinical laboratory tests is boosting the adoption of novel IVD tests worldwide. In June 2023, Toray Industries, Inc. received marketing approval from Japan’s Ministry of Health, Labour and Welfare for its Toray APOA2-iTQ used to diagnose pancreatic cancer. Moreover, in March 2023, Abbott received U.S. FDA clearance for its novel laboratory Traumatic Brain Injury (TBI) blood test in the U.S. Increasing approvals of IVD tests for life-threatening diseases are expected to create new opportunities in the untapped market.

Key players in the market undertake various strategies to strengthen their position and offer their customers diverse, technologically advanced & innovative products. New product launches and partnerships are the most prominently adopted by companies to attract more customers. For instance, in March 2023, BD received 510(k) clearance for BD Vaginal Panel on the BD COR System to detect infectious causes of vaginitis. In August 2023, the Precision Medicine Centre (PMC) formed a partnership with the Regional Molecular Diagnostic Service (RMDS) to implement genomic technology for the diagnosis of cancer in Northern Ireland.

Request a free sample copy or view the report summary: In Vitro Diagnostics Market Report

In Vitro Diagnostics Market Report Highlights

Molecular diagnostics is anticipated to grow at the fastest CAGR from 2024 to 2030 owing to the rising adoption and usage rate

Reagents held the largest market share owing to the surge in demand for genetic testing and enhanced availability of technologically advanced diagnostic tests in lower and middle-income countries with unmet clinical needs

The infectious diseases application segment held the largest market share owing to the large volume of testing for infectious diseases globally

North America dominated the global market in 2023 owing to the high demand for novel technologies, a large pool of key players, high prevalence of diseases, and advanced healthcare infrastructure

In Vitro Diagnostics Market Segmentation

Grand View Research has segmented the global in vitro diagnostics (IVD) market report based on product, technology, application, end-use, test location, and region:

IVD Product Outlook (Revenue, USD Million, 2018 - 2030)

Instruments

Reagents

Services

IVD Technology Outlook (Revenue, USD Million, 2018 - 2030)

Immunoassay

Instruments

Reagents

Services

Hematology

Instruments

Reagents

Services

Clinical Chemistry

Instruments

Reagents

Services

Molecular Diagnostics

Instruments

Reagents

Services

Coagulation

Instruments

Reagents

Services

Microbiology

Instruments

Reagents

Services

Others

Instruments

Reagents

Services

IVD Application Outlook (Revenue, USD Million, 2018 - 2030)

Infectious Diseases

Diabetes

Oncology

Cardiology

Nephrology

Autoimmune Diseases

Drug Testing

Others

IVD Test Location Outlook (Revenue, USD Million, 2018 - 2030)

Point of Care

Home-care

Others

IVD End-use Outlook (Revenue, USD Million, 2018 - 2030)

Hospitals

Laboratory

Home-care

Others

IVD Regional Outlook (Revenue, USD Million, 2018 - 2030)

North America

U.S.

Canada

Europe

UK

Germany

France

Spain

Italy

Russia

Denmark

Sweden

Norway

Asia Pacific

Japan

China

India

South Korea

Australia

Thailand

Singapore

Latin America

Brazil

Mexico

Argentina

Middle East and Africa (MEA)

South Africa

Saudi Arabia

UAE

Kuwait

List of Key Players of In Vitro Diagnostics (IVD) Market

Abbott

bioMérieux SA

QuidelOrtho Corporation

Siemens Healthineers AG

Bio-Rad Laboratories, Inc.

Qiagen

Sysmex Corporation

Charles River Laboratories

Quest Diagnostics Incorporated

Agilent Technologies, Inc.

Danaher Corporation

BD

F. Hoffmann-La Roche Ltd.

Browse Full Report: In Vitro Diagnostics Market Report

[gastroenterologyucgconferences]

Understanding Jaundice: Causes, Symptoms, Diagnosis, and Treatment

What is Jaundice?

Jaundice is a medical condition characterized by the yellowing of the skin and the whites of the eyes. This yellow color is due to an excess of bilirubin, a yellow-orange bile pigment, in the blood. Bilirubin is produced during the normal breakdown of red blood cells and is usually processed by the liver. When there is a disruption in this process, jaundice can occur.

Causes of Jaundice

Jaundice can be caused by various underlying conditions, which are broadly categorized into pre-hepatic (before bile is made in the liver), hepatic (issues within the liver), and post-hepatic (after bile is made).

Pre-Hepatic Causes:

Hemolytic anemia: Accelerated breakdown of red blood cells increases bilirubin production.

Sickle cell anemia: Abnormal red blood cells break down more rapidly.

Malaria: Infection causes red blood cell destruction.

Hepatic Causes:

Hepatitis: Inflammation of the liver reduces its ability to process bilirubin.

Cirrhosis: Chronic liver damage from various causes leads to scarring and liver dysfunction.

Liver cancer: Malignant cells impair liver function.

Genetic disorders: Conditions like Gilbert's syndrome affect bilirubin metabolism.

Post-Hepatic Causes:

Gallstones: Block the bile ducts, preventing bilirubin excretion.

Pancreatic cancer: Tumors can compress the bile ducts.

Biliary atresia: Congenital condition where bile ducts are absent or blocked.

Symptoms of Jaundice

Yellowing of the skin and eyes

Dark urine

Pale stools

Itchy skin

Fatigue

Abdominal pain

Weight loss

Vomiting

Diagnosis of Jaundice

Diagnosing jaundice involves a combination of clinical evaluation and laboratory tests:

Physical Examination: A doctor will look for signs of jaundice and other related symptoms.

Laboratory Tests:

Bilirubin Levels: Blood tests to measure total and direct (conjugated) bilirubin.

Complete Blood Count (CBC): To check for hemolytic anemia.

Liver Function Tests (LFTs): To assess the liver's health and functioning.

Viral Hepatitis Panel: To detect hepatitis viruses.

Imaging Studies:

Ultrasound: To visualize the liver, gallbladder, and bile ducts.

CT Scan/MRI: For more detailed imaging.

Liver Biopsy: In some cases, a small tissue sample from the liver may be examined to determine the cause of liver dysfunction.

Treatment of Jaundice

The treatment of jaundice focuses on addressing the underlying cause:

Pre-Hepatic Jaundice:

Treating the underlying hemolytic disorders or infections.

Hepatic Jaundice:

Hepatitis: Antiviral or immunosuppressive drugs.

Cirrhosis: Lifestyle changes, medications, or possibly a liver transplant.

Liver Cancer: Surgery, chemotherapy, or radiation therapy.

Post-Hepatic Jaundice:

Gallstones: Medications to dissolve stones or surgery to remove them.

Tumors: Surgical removal, chemotherapy, or radiotherapy.

Biliary Atresia: Surgery to reconstruct bile ducts or liver transplant.

Managing Jaundice

Dietary Changes: Eating a balanced diet rich in fruits, vegetables, and lean protein can support liver health.

Hydration: Drinking plenty of fluids helps maintain kidney function and aids in the excretion of bilirubin.

Avoid Alcohol: Alcohol can exacerbate liver damage.

Medication Management: Some medications can cause liver damage; consult a doctor before taking new medications.

When to See a Doctor

Seek medical attention if you notice symptoms of jaundice, especially if accompanied by severe abdominal pain, confusion, or blood in vomit or stool, as these could indicate a serious underlying condition.

Understanding jaundice and its underlying causes, symptoms, diagnosis, and treatment is crucial for effective management and recovery. If you suspect jaundice, it's important to seek medical attention promptly.

Important Information:

Conference Name: 14th World Gastroenterology, IBD & Hepatology Conference Short Name: 14GHUCG2024 Dates: December 17-19, 2024 Venue: Dubai, UAE Email:  gastroutilitarianconferences@gmail.com Visit: https://gastroenterology.universeconferences.com/ Call for Papers: https://gastroenterology.universeconferences.com/submit-abstract/ Register here: https://gastroenterology.universeconferences.com/registration/ Exhibitor/Sponsor: https://gastroenterology.universeconferences.com/exhibit-sponsor-opportunities/ Call Us: +12073070027 WhatsApp Us: +442033222718

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Hydroxyurea 500 mg medication price

Hydrea used concomitantly with irradiation therapy is intended for use in the local control of primary squamous cell (epidermoid) carcinomas of the head and neck, excluding the lip, and carcinoma of the cervix.

Special warnings and precautions

Special warnings and precautions for use Warnings Treatment with hydroxycarbamide should not be initiated if bone marrow function is markedly depressed (see 4.3 Contraindications). Bone marrow suppression may occur, and leukopenia is generally its first and most common manifestation. Thrombocytopenia and anaemia occur less often, and are seldom seen without a preceding leukopenia. However, the recovery from the myelosuppression is rapid when therapy is interrupted. It should be borne in mind that bone marrow depression is more likely in patients who have previously received radiotherapy or cytotoxic cancer chemotherapeutic agents; hydroxycarbamide should be used cautiously in such patients. Patients who have received irradiation therapy in the past may have an exacerbation of post-irradiation erythema. Cases of haemolytic anaemia in patients treated with hydroxycarbamide for myeloproliferative diseases have been reported (See 4.8 Undesirable effects). Patients who develop persistent anaemia should have laboratory tests evaluated for haemolysis. In the setting of confirmed diagnosis of haemolytic anaemia, hydroxycarbamide should be discontinued. Severe anaemia must be corrected with whole blood replacement before initiating therapy with hydroxycarbamide. Since hydroxycarbamide may cause drowsiness and other neurologic effects, alertness may be impaired in driving and operating machinery. (See 4.7 Effects on ability to drive and use machines). Patients should be advised to maintain adequate fluid intake. Patients should consult with their physician regarding missed doses. Fatal and nonfatal pancreatitis have occurred in HIV-infected patients during therapy with hydroxycarbamide and didanosine, with or without stavudine. Hepatotoxicity and hepatic failure resulting in death have been reported during post-marketing surveillance in HIV-infected patients treated with hydroxycarbamide and other antiretroviral agents. Fatal hepatic events were reported most often in patients treated with the combination of hydroxycarbamide, didanosine, and stavudine. This combination should be avoided. Peripheral neuropathy, which was severe in some cases, has been reported in HIV-infected patients receiving hydroxycarbamide in combination with antiretroviral agents, including didanosine, with or without stavudine. Interstitial lung disease including pulmonary fibrosis, lung infiltration, pneumonitis, and alveolitis/allergic alveolitis have been reported in patients treated for myeloproliferative neoplasm and may be associated with fatal outcome. Patients developing pyrexia, cough, dyspnea, or other respiratory symptoms should be closely monitored, investigated and treated. Promptly discontinue hydroxycarbamide and treat with corticosteroids to resolve the pulmonary events (See 4.8 Undesirable effects).

Erythrocytic Abnormalities

Megaloblastic erythropoiesis, which is self-limiting is often seen early in the course of hydroxycarbamide therapy. The morphological change resembles pernicious anaemia, but is not related to Vitamin B12 or folic acid deficiency. The macrocytosis may mask the incidental development of folic acid deficiency; thus, prophylactic administration of folic acid may be warranted. Hydroxycarbamide may also delay plasma iron clearance and reduce the rate of iron utilisation by erythrocytes, but it does not appear to alter the red blood cell survival time. Hydrea v11.0 4 Hydroxycarbamide should be used with caution in patients with marked renal dysfunction. In patients receiving long-term therapy with hydroxycarbamide for myeloproliferative disorders, such as polycythemia vera and thrombocythemia, secondary leukemia has been reported. It is unknown whether this leukemogenic effect is secondary to hydroxycarbamide or associated with the patients’ underlying disease. Cutaneous vasculitic toxicities including vasculitic ulcerations and gangrene have occurred in patients with myeloproliferative disorders during therapy with hydroxycarbamide. Theses vasculitic toxicities were reported most often in patients with a history of or currently receiving interferon therapy. Due to potentially severe clinical outcomes for the cutaneous vasculitic ulcers reported in patients with myeloproliferative disease, hydroxycarbamide should be discontinued if cutaneous vasculitic ulcerations develop and alternative cytoreductive agents should be initiated as indicted.

Use in pregnancy

Hydroxycarbamide can cause fetal harm when administered to a pregnant woman and has been demonstrated to be a potent teratogenic agent in animals. Malformations have been observed in the offspring of rabbits and rats given doses equivalent to one-third to twice the maximum human dose, respectively. There are no adequate and well-controlled studies in pregnant women. If this medicine is used during pregnancy or if the patient becomes pregnant while on hydroxycarbamide therapy, the patient should be apprised of the potential hazard of the fetus. Women of childbearing potential should be advised to avoid becoming pregnant while taking hydroxycarbamide.

Use in lactation

Hydroxycarbamide is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from hydroxycarbamide, breast feeding is not recommended during hydroxycarbamide therapy.

Above content source: https://www.911globalmeds.com/info/1322-1-Hydroxyurea-Hydrea-Droxia-Medication-Patient-Information-In-English.pdf

The guaranteed Lowest Cost of Hydrea / Hydroxyurea 500 mg @ $ 0.67 per capsule Online.

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Types, Symptoms and Risk factors of Pancreatic Cancer

Pancreatic cancer is a type of cancer that originates in the pancreas, a glandular organ located behind the stomach. The pancreas plays a crucial role in digestion and blood sugar regulation by producing enzymes and hormones like insulin.

Pancreatic cancer typically starts in the cells lining the ducts of the pancreas, which are responsible for carrying digestive juices. Over time, these cancerous cells can grow and spread to other parts of the pancreas or to nearby organs and tissues, as well as to distant parts of the body (metastasis).

Types of Pancreatic Cancer:

Exocrine Pancreatic Cancer: The most common type, accounting for about 95% of cases, originates in the exocrine cells that produce digestive enzymes. The most common form of exocrine pancreatic cancer is adenocarcinoma.

Endocrine Pancreatic Cancer (Pancreatic Neuroendocrine Tumors): Less common, these tumors develop in the endocrine cells of the pancreas, which produce hormones like insulin and glucagon. These tumors are often less aggressive than exocrine pancreatic cancer.

Symptoms of Pancreatic Cancer:

Abdominal pain: Typically starts in the upper abdomen and may radiate to the back.

Jaundice: Yellowing of the skin and eyes, often accompanied by dark urine and pale stools.

Unexplained weight loss: Significant weight loss without changes in diet or exercise.

Loss of appetite:Decreased interest in eating, often accompanied by nausea and vomiting.

New-onset diabetes: Diabetes that develops suddenly without a clear cause.

Digestive problems: Changes in bowel habits, indigestion, or difficulty digesting fatty foods.

Risk Factors for Pancreatic Cancer:

Age:Risk increases with age, with the majority of cases occurring in people over 60.

Smoking:Cigarette smoking is one of the most significant risk factors for pancreatic cancer.

Family history: Having close relatives with pancreatic cancer increases the risk.

Chronic pancreatitis: Long-term inflammation of the pancreas raises the risk.

Obesity: Being overweight or obese increases the likelihood of developing pancreatic cancer.

Diabetes: Chronic diabetes may slightly increase the risk of pancreatic cancer.

Dietary Factors: High intake of red meat, processed meats, and saturated fats, as well as low intake of fruits and vegetables, may contribute to an increased risk

 Diagnosis and Treatment:

Diagnosis:Typically involves imaging tests such as CT scans, MRI, or endoscopic ultrasound, as well as biopsy for confirmation.

Treatment: Options include surgery, chemotherapy, radiation therapy, targeted therapy, immunotherapy, and clinical trials.

Prognosis:Pancreatic cancer is often diagnosed at an advanced stage, which makes it challenging to treat. The prognosis varies depending on the stage of the cancer, with early detection associated with better outcomes.

Pancreatic cancer is often diagnosed at an advanced stage, making it one of the deadliest forms of cancer. However, advancements in the treatment of pancreatic cancer in Bangalore and early detection strategies offer hope for improved outcomes and better quality of life for patients. Regular screening for those at high risk and awareness of symptoms are crucial for early detection and treatment.