#oropharyngeal swab

[tmmediapharma]

Find the Top Quality of oropharyngeal swab (TMC 074) at TM Media

If you are looking for oropharyngeal swab manufactured by TM Media is a specialized medical tool designed for the collection of samples from the oropharynx, which includes the back of the throat and tonsillar areas. This swab is commonly employed in diagnostic procedures to gather specimens for the detection of various infections, including respiratory viruses and bacteria. The swab features a soft, flexible tip for patient comfort during the sampling process. Oropharyngeal swabs are vital in medical settings, contributing to the accurate diagnosis and management of infectious diseases affecting the respiratory and oropharyngeal regions.

Visit the Website - https://www.tmmedia.in/

[covid-safer-hotties]

Also preserved in our archive

By Dr. Chinta Sidharthan

Unvaccinated volunteers who contracted COVID-19 in a human challenge study showed significant memory and executive function decline lasting up to a year, despite no reported subjective symptoms, prompting new questions about the virus’s long-term cognitive effects.

In a recent study published in the journal EClinicalMedicine, a team of researchers from the United Kingdom examined the cognitive deficits associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. They conducted the first human challenge study among a prospectively controlled group of unvaccinated SARS-CoV-2 naive volunteers, who were inoculated with the wild-type strain and observed for long-term cognitive problems.

Background Substantial research now indicates that long-lasting cognitive deficits impacting memory, comprehension, and concentration occur even after mild coronavirus disease 2019 (COVID-19) cases. A large proportion of individuals who recover from COVID-19 continue to experience “brain fog,” memory lapses, and difficulty forming words for months after the initial acute infection.

Cross-sectional and longitudinal studies have observed cognitive decline in patients one year after the infection, and brain scans have detected shrinkage in areas of the brain related to cognition and memory. Furthermore, blood tests in patients hospitalized due to SARS-CoV-2 infections have detected elevated levels of brain injury markers, such as neurofilament light (NfL) and glial fibrillary acidic protein (GFAP), indicative of potential future cognitive problems, though markers like Tau were not significantly different between infected and uninfected groups.

However, the retrospective nature of these studies has posed difficulties in accounting for the role of occupations, pre-existing health conditions, and social factors in the risk of cognitive deficits after COVID-19. Furthermore, the pace at which cognitive deficits develop after mild SARS-CoV-2 infections and the duration of these deficits remains unclear.

About the study In the present study, the researchers challenged a group of unvaccinated, SARS-CoV-2 naive volunteers with the wild-type strain of the virus in controlled conditions. The volunteers were then quarantined and followed up to determine the long-term cognitive impacts of COVID-19.

The researchers ensured that all the ethical guidelines were followed in this human challenge study, and written consent was obtained from all the volunteers, who were also compensated for the time spent in quarantine.

The study enrolled 36 healthy adults between 18 and 30 years who had never been vaccinated against or infected with SARS-CoV-2. Of these, 18 participants were classified as infected, while 16 were uninfected. The volunteers underwent extensive tests and screening, including blood tests, chest radiography, body mass index, and assessments for COVID-19 risk factors.

The participants were then intranasally inoculated with SARS-CoV-2 and quarantined for at least two weeks. The follow-ups occurred at non-regular intervals for up to a year after the inoculation.

The viral loads in all the infected participants were monitored twice a day through naso- and oropharyngeal swabs. Additionally, the researchers administered a subjective symptom survey thrice daily to track the symptoms. The participants were categorized based on whether they experienced a sustained viral infection, and six were administered remdesivir as a precaution.

The researchers measured the participants' cognitive performance through 11 computer-based tasks that measured various cognitive domains, such as reaction time, memory, spatial reasoning, and planning. The participants were required to perform these tasks at baseline, on each day of the quarantine, and at each of the five follow-ups. The primary cognitive measure was the baseline-corrected global cognitive composite score or bcGCCS.

Additionally, the researchers also analyzed the levels of brain injury markers, such as neurofilament light (NfL) and glial fibrillary acidic protein (GFAP), in the blood samples obtained from the participants.

Results The study found that bcGCCS scores indicated that the infected individuals exhibited significant cognitive deficits compared to the uninfected individuals. These deficits were sustained for almost a year, with no recovery or improvements noted. Despite these objective cognitive deficits, none of the infected volunteers reported subjective cognitive symptoms.

The cognitive area that showed the largest deficit was memory-related tasks, such as those measuring immediate and delayed memory recall. The infected individuals performed worse than the uninfected ones on memory-related and executive planning tasks.

The cognitive tasks were grouped based on whether learning effects were observed across sessions, and the results indicated that the cognitive differences between the uninfected and infected individuals were robust even after accounting for learning effects.

Furthermore, some brain injury biomarkers in the serum, such as GFAP, were higher in the infected participants than in the uninfected ones, but other markers, such as Tau and NfL, were not significantly different between the two groups.

Although these findings indicated that SARS-CoV-2 infections resulted in measurable differences in various aspects of cognitive decline, especially in the areas of memory and executive function, the statistical tests revealed no significant correlation between cognitive deficits and viral load, brain markers, and symptom severity.

Conclusions The study indicated that while objective and measurable changes could be observed in various aspects of cognitive performance due to SARS-CoV-2 infections, further research is essential to understand the biological mechanisms behind these cognitive deficits. The researchers believe that more long-term studies on larger cohorts are required to understand the long-term impact of COVID-19. Importantly, the study results suggest that these cognitive changes might persist even in the absence of subjective symptoms, highlighting the need for more sensitive assessment tools.

Journal reference: Trender, W., Hellyer, P. J., Killingley, B., Kalinova, M., Mann, A. J., Catchpole, A. P., Menon, D., Needham, E., Thwaites, R., Chiu, C., Scott, G., & Hampshire, A. (2024). Changes in memory and cognition during the SARS-CoV-2 human challenge study. EClinicalMedicine, 76. DOI:10.1016/j.eclinm.2024.102842, www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00421-8/fulltext

[helthcareheven]

Poultry Pathology Perspectives: Insights from Diagnostics

Introduction to Poultry Diagnostics

Poultry diagnostic refers to the identification and analysis of diseases and health issues affecting poultry flocks. Proper diagnostics is crucial for poultry producers to maintain flock health and productivity. This article will explore some key aspects of poultry diagnostic including types of testing, sample collection, common diseases, and the role diagnostics plays in disease prevention and treatment. Types of Diagnostic Testing

There are several types of diagnostic tests that can be used to determine the health status of poultry flocks: Serology: Serology tests, also known as antibody tests, detect antibodies in blood serum that are produced in response to certain diseases. These tests can identify if birds have been previously exposed to pathogens like avian influenza or Newcastle disease. Microbiology: Microbiological tests identify the presence of bacteria, viruses, parasites or other microorganisms in samples. Culturing and PCR (polymerase chain reaction) techniques are commonly used to detect specific pathogens. Necropsy: A postmortem examination of dead birds, known as a necropsy, can provide visual clues to diagnosis. Tissue samples collected during necropsy can then undergo further lab testing. Molecular Diagnostics: Advanced molecular diagnostic methods like real-time PCR have revolutionized poultry disease detection. They provide rapid, sensitive identification of pathogens from different sample types. Sample Collection and Submission

Proper sample collection and handling is critical for accurate diagnostic results. Samples must be properly stored and transported to avoid deterioration. The most common sample types submitted for poultry diagnostics include: - Oropharyngeal (choanal cleft) and cloacal swabs: Used for microbiological testing. - Serum: Collected from the brachial vein for serology tests. - Tissues: Organ tissues collected during necropsy examinations. - Eggs: Yolk, albumen and embryos can be tested for certain pathogens. - Feces: Help identify enteric (intestinal) infections and coccidiosis. Common Poultry Diseases Tested

Some significant diseases frequently evaluated through poultry diagnostic include: Avian Influenza: A highly contagious viral disease and causative agent of bird flu outbreaks. Rapid PCR tests are commonly used. Marek's Disease: A ubiquitous herpesvirus infection causing tumors. PCR analysis of tissue samples enables diagnosis. Infectious Bronchitis: A coronavirus infecting the respiratory and urogenital tracts. RT-PCR tests are highly sensitive and specific. Newcastle Disease: A devastating viral pathogen affecting many bird species worldwide. Microbiological culturing and molecular tests are used. Salmonellosis: Zoonotic bacterial disease associated with Salmonella enterica. Bacteria is isolated through culture and identified. Coccidiosis: An enteric parasitic disease primarily affecting young chickens and turkeys. Fecal flotation or molecular tests detect oocyst shedding. The Role of Diagnostics in Disease Management

Timely and accurate diagnostics is essential for controlling disease outbreaks and minimizing economic losses in poultry production. Knowing disease status allows for: - Rapid treatment and containment: Prompt diagnosis leads to quicker therapeutic intervention and prevents spread. - Monitoring flock health: Routine monitoring through diagnostics helps detect subclinical infections and implement preventive measures. - Vaccine selection: Diagnostics guides proper vaccine selection to provide protection against significant prevalent pathogens. - Trade and movement: Many countries require diagnostic testing and certification for import/export of poultry and products. - Surveillance programs: Industry-wide surveillance through laboratory submission aids early detection of foreign diseases. In conclusion, modern poultry diagnostics employs a range of laboratory tests tailored to each situation. Strategic use of diagnostics supports optimum flock health, productivity and food safety through early disease identification and management. Diagnostics is an indispensable tool for disease prevention and control in the poultry industry.

[rnomics]

Biosensors, Vol. 13, Pages 988: Detection of Reverse Transcriptase LAMP-Amplified Nucleic Acid from Oropharyngeal Viral Swab Samples Using Biotinylated DNA Probes through a Lateral Flow Assay

This study focuses on three key aspects: (a) crude throat swab samples in a viral transport medium (VTM) as templates for RT-LAMP reactions; (b) a biotinylated DNA probe with enhanced specificity for LFA readouts; and (c) a digital semi-quantification of LFA readouts. Throat swab samples from SARS-CoV-2 positive and negative patients were used in their crude (no cleaning or pre-treatment) forms for the RT-LAMP reaction. The samples were heat-inactivated but not treated for any kind of nucleic acid extraction or purification. The RT-LAMP (20 min processing time) product was read out by an LFA approach using two labels: FITC and biotin. FITC was enzymatically incorporated into the RT-LAMP amplicon with the LF-LAMP primer, and biotin was introduced using biotinylated DNA probes, specifically for the amplicon region after RT-LAMP amplification. This assay setup with biotinylated DNA probe-based LFA readouts of the RT-LAMP amplicon was 98.11% sensitive and 96.15% specific. The LFA result was further analysed by a smartphone-based IVD device, wherein the T-line intensity was recorded. The LFA T-line intensity was then correlated with the qRT-PCR Ct value of the positive swab samples. A digital semi-quantification of RT-LAMP-LFA was reported with a correlation coefficient of R2 = 0.702. The overall RT-LAMP-LFA assay time was recorded to be 35 min with a LoD of three #RNA copies/µL (Ct-33). With these three advancements, the nucleic acid testing-point of care technique (NAT-POCT) is exemplified as a versatile biosensor platform with great potential and applicability for the detection of pathogens without the need for sample storage, transportation, or pre-processing. https://www.mdpi.com/2079-6374/13/11/988?utm_source=dlvr.it&utm_medium=tumblr

[cailynnjohnson]

monkeypox pcr test kit

Monkeypox PCR test kit is a real-time PCR technique for detecting MPXV DNA in vesicles or pustules, nasopharyngeal swabs, oropharyngeal swabs, serum, and whole blood. This product is furnished for research use only. Not for diagnostic or therapeutic use.

[dhxprotectiveequipment]

Donghaixiang Providing High-Quality And Safe Virus Sampling Materials

The COVID-19 pandemic has drastically changed our world, and has highlighted the importance of having proper virus sampling materials. Virus sampling tubes have become an essential tool in conducting COVID-19 tests and research, and have played a critical role in controlling the spread of the virus. In this article, we will focus on the Virus Sampling Tube Factory, which produces high-quality and safe virus sampling tubes.

Introduction to the Virus Sampling Tube Factory

Zhejiang Donghaixiang Medical Device Co., Ltd. is a leading manufacturer of virus sampling tubes and supplies for global customers. With years of experience in the field, they have served clients in various industries, including medical, research, and pharmaceutical industries.

The Zhejiang Donghaixiang Medical Device Co., Ltd. is located in China, and its production capacity can meet the needs of customers worldwide. They have a team of experienced professionals who handle all stages of production, from raw material procurement to finished product quality control. The factory has also implemented strict quality control measures to ensure that all products meet international standards.

Product Features

The Virus Sampling Tube Factory provides a wide range of virus sampling tubes that are diverse in size, shape, and material. The products are designed to collect and preserve various types of viruses, including coronaviruses, influenza viruses, and other respiratory viruses.

The tube materials are made of high-quality medical-grade materials, which ensure the safety and reliability of the products. These materials include medical-grade polypropylene and polystyrene, which are non-toxic, non-pyrogenic, and do not contain DNase or RNase. Their state-of-the-art production facility also applies advanced technology in the production of virus sampling tubes to ensure maximum effectiveness.

The products are designed to ensure ease of use and are compatible with various sampling methods and testing instruments. They also have an excellent sealing performance, which guarantees that the collected samples are leak-proof and safe to transport.

Product Types

The Zhejiang Donghaixiang Medical Device Co., Ltd. produces various types of virus sampling tubes that cater to the needs of different customers. These include:

Nasal Swab Tube: This type of tube is designed for the collection of nasopharyngeal and oropharyngeal samples. It is suitable for testing respiratory viruses such as coronaviruses, influenza viruses, and others.

Saliva Collection Tube: This type of tube is designed for the collection of saliva samples. It is suitable for testing for respiratory viruses such as coronaviruses, influenza viruses, and others.

Blood Collection Tube: This type of tube is designed for the collection of blood samples. It is suitable for testing for blood-borne viruses such as hepatitis B and C viruses, HIV, and others.

Urine Collection Tube: This type of tube is designed for the collection of urine samples. It is suitable for testing for urinary tract infections caused by bacteria, viruses, and fungi.

Product Application Fields

The Virus Sampling Tube Factory's products can be applied to various fields, including:

Medical Industry: They can be used in the collection and preservation of clinical samples for use in diagnosis and treatment of various diseases, including COVID-19.

Research Industry: They can be used in scientific research for studying viruses, bacteria, fungi, and other microorganisms.

Pharmaceutical Industry: They can be used in the development and production of vaccines, drugs, and other medical products.

The Virus Sampling Tube Factory is an essential player in the fight against COVID-19. Their commitment to producing high-quality virus sampling tubes ensures that healthcare professionals and researchers have the necessary tools to combat the virus. Their products meet international standards, and their team of professionals ensures that all production processes are safe and reliable.

In conclusion, the Virus Sampling Tube Factory provides an excellent solution for customers in need of virus sampling tubes. Their commitment to quality and safety has made them one of the most reliable manufacturers of virus sampling tubes in the world. With their products, healthcare professionals and researchers can continue their essential work in combating the COVID-19 pandemic and other infectious diseases.

[mysticalfungalaxy]

Covid-19 Diagnostics Market Booming Worldwide Opportunity, Competitive Analysis, Future Prospects 2032 | FMI

The Covid-19 Diagnostics Market is expected to exceed US$ 204.51 billion by 2032, growing at a 7.7% CAGR.

With the latest insights and statistics from the biggest pharmaceutical and healthcare device manufacturers across the globe, FMI presents an extensive analysis on Covid-19 Diagnostics market.

Gain complete access to the report @ https://www.futuremarketinsights.com/reports/covid-19-diagnostics-market

FMI offers insights into the market data on over 5000+ drugs for more than 100 countries, which further aids the research on current and upcoming market scenario for the Covid-19 Diagnostics market. Our expert researchers and analysts for healthcare tracks the data of established players as well as new entrants in medical industry to provide an unbiased analysis for a sound and financial decision.

Over the past decade, healthcare sector has been expanding remarkably, following the advent of artificial Intelligence and the Internet of Things integrated medical devices. Advancement in technology has created impressive scope within the medical sector for diagnostics and therapeutics.

The report offers extensive data sets validating key trends impacting growth in the Covid-19 Diagnostics market. It offers insights into strategies adopted by the key players rise and address the concerns that will challenge the growth of Covid-19 Diagnostics market. With our extensive research and information about the past, current and future market scenario, the Covid-19 Diagnostics market report will help and identify the concerns, for a smooth-sail of the small & medium as well as large enterprises.

Coronavirus screening typically involve testing for the presence of the SARS-CoV-2 virus or its antibodies in a person's body.

Competitive Analysis

By Prominent Market Players

Veredus Laboratories

Thermo Fisher Scientific, Inc.

Quidel Corporation

Perkin Elmer, Inc.

Neuberg Diagnostics

Mylab Discovery Solutions Pvt Ltd.

Luminex Corporation

Laboratory Corporation of America Holdings

Hologic Inc.

Others

Get a Full PDF Sample Copy of the Latest Reports @ https://www.futuremarketinsights.com/reports/sample/rep-gb-12366

Covid-19 Diagnostics Market: Segmentation

Product Type

Instruments

Test Kits

Reagents and Consumables

Sample Type

Oropharyngeal & Nasopharyngeal Swabs

Blood

Urine

Others

Technology

PCR

ELISA

POC

Why Future Market Insights?

Comprehensive analysis on evolving purchase pattern across different geographies

Detailed insights of market segments and sub-segments for historical as well as forecast period

A competitive analysis of  prominent players and emerging players in the Covid-19 Diagnostics market

Detailed information about the product innovation, mergers and acquisitions lined up in upcoming years

Ground breaking research and market player-centric solutions for the upcoming decade according to the present market scenario

[medisupplements]

Lightning X Stocked EMS/EMT Trauma & Bleeding First Aid Responder Medical Backpack + Kit Price: [price_with_discount] Customer satisfaction rating 4.5 (according to Amazon product Details) THE BAG: The LXPB89 is a compact backpack that features four main exterior compartments plus a quick-access velcro compartment behind the lumbar panel. The front, sides and bottom feature modular loops (MOLLE) to attach additional bags or hang gear. The back of the main compartment includes a zippered pouch designed to hold a hydration bladder, with ports at the top for drinking tube access. The shoulder straps are fully adjustable from all points to suit different body types and also feature a chest strap and webbing loops to attach a drinking tube. The rear of the bag is designed with padded mesh lumbar panels to make long periods of use more comfortable on your back. Inside the two main compartments are smaller mesh panels that are perfect for organizing your gear and keeping items separate. Each opening consists of extra large double zippers with drawstring zipper pulls for easy opening and closing of the compartments. ***THE KIT: Forceps, Kelly Hemostats, Trauma Scissors, Bandage Scissors, Flashlight, Ammonia Ampoules (10), Plasters (100), 4" x 4" Gauze Pads (50), Gauze Rolls 2" (2) , 3" Gauze Roll (2), 4" Gauze Roll (2), 2" Self-Adherent Bandage (2), 2" Ace Elastic Bandage (2), ABD Pad 5 " x 7" (2), 8" x 10" ABD Pad (2), 1" Roll of Cloth Tape, Iodine Pads (10), Isopropyl Alcohol Pads (10), 1/ Triple Antibiotic Ointment 2 oz, Instant Cold Packs (2), Eye Pads (2), Triangular Bandage (2), Eye Wash Irrigation Solution, Exam Gloves (4), SAM Universal Finger Splint, Oral Glucose Gel, Adult Blood Pressure Cuff with Case, Sprague Stethoscope, CPR Mask, Oropharyngeal Airway Kit (6), Sting and Bite Relief Swabs (10), Vaseline Gauze (2), First Aid Guide, Hemostatic Gauze rapid coagulation 4" x 4" da (2), Dyna-Stopper Trauma Pressure Dressing, 12" x 30" Multi Trauma Pad, Z-Fold Compressed Crinkle Gauze 4.5" x 4.1yd, Israeli Pressure Bandage 4", First Aid Antiseptic Spray 2oz, Burn Spray 2oz, Adult BVM Bag, 36" Roll Splint, Emerge Cy Foil Mylar Blanket. CONTENTS OF THE COMPLETE KIT INDICATED BELOW IN THE DESCRIPTION Modular (MOLLE) loops throughout for attaching external pouches or hanging additional gear Four main exterior compartments, plus a rear Velcro compartment Measures 13"(L) x 9"(W) x 18"(H) Lightning X Products Limited Lifetime Warranty #Lightning #Stocked #EMSEMT #Trauma #Bleeding #Aid #Responder #Medical #Backpack #Kit See more related items: Lightning X Stocked EMS/EMT Trauma & Bleeding First Aid Responder Medical Backpack + Kit Read More: This site is affiliated with Amazon

[daangene]

COVID-19 Antigen Rapid Testing Kit (Colloidal Gold) for Home/Self-test Use

The COVID-19 Antigen Rapid Testing Kit (Colloidal Gold) is a covid 19 self test kit used for the qualitative detection of COVID-19 antigen in nasopharyngeal swab (NPS) and oropharyngeal swab (OPS) specimens by colloidal gold immunochromatography assay. In vitro qualitative detection of SARS-CoV-2 antigen in human anterior nasal swab specimens of asymptomatic people or people suspected of COVID-19 infection. COVID-19 Self Test Kit Features ◆ User-friendly: Easy operation

◆ Fast: Get accurate result in 15 minutes

◆ Convenient: Stored at room temperature

◆ High performance: Sensitivity: 84.07% Specificity: 100% (WHO recommended sensitivity≥80% and specificity≥97% )

Self COVID-19 Test Kit Specification Target SARS-CoV-2 antigen Specimen Type Anterior nasal specimens Storage and shelf life Stored at 2-30°C before opening the package with a validity period of 18 months Certificate CE Test Principle Colloidal gold immunochromatography Performance Sensitivity: 84.07% Specificity: 100%

Self-Test COVID-19 Test Kit Order Information Cat. No. Description Package Storage and shelf life XG0310-01 COVID-19 Antigen Rapid Testing Kit (Colloidal Gold) 1 Test/Kit 2-30℃, 18 months XG0310-10 10 Tests/Kit

[longhaulerbear]

(From 2020)

It is well established that SARS–CoV-2 can be isolated from rectal swabs and faeces, even in patients who do not display respiratory symptoms and are negative for SARS–CoV-2 in nasopharyngeal and throat swabs [2]. Digestive symptoms attributed to COVID-19 include nausea, vomiting, diarrhoea, abdominal pain and change in appetite [3]. Our patient presented with four of the latter symptoms and displayed no respiratory symptoms pertaining to the virus.

SARS–CoV-2 may invade the intestinal wall due to high expression of viral receptor ACE2 in the gut wall, thereby impairing barrier function and allowing microbial translocation [2, 3]. This yields a number of hypotheses.

We argue that SARS–CoV-2 is the causative agent of appendicitis in this patient. The highly atypical histological appearance of the appendix specimen, particularly the occasional micro thrombi, fibrinoid necrosis of the blood vessels and perivascular lymphocytic inflammatory infiltrate in the specimen points towards the influence of SARS–CoV-2. These findings are represented in several reports of lung specimens, where lymphocytic infiltration and fibrinous micro thrombi are prominent features [4, 5]. The positive PCR result further supports our diagnosis.

In addition, haematological and biochemical parameters were highly suggestive of COVID-19-induced sepsis; sustained lymphopenia, raised ferritin (5352 μg/l), troponin (148 ng/l) and creatinine kinase (200 iu/l maximally) and myocarditis have all been reported in SARS–CoV-2 infection [6].

Route of transmission to the appendix is undetermined. The presence of SARS–CoV-2 RNA in stool samples of patients with gastrointestinal symptoms alludes to the possibility of faeco-oral transmission [2]. Infection may additionally enter the gastrointestinal tract via oropharyngeal contamination, also enabling bacterial translocation and appendicitis.

Another hypothesis is that the presence of SARS–CoV-2 in the gastrointestinal system was coincidental, with appendicitis resulting from an appendicolith forming concomitantly with infection. The CT and macroscopic biopsy appearances have not substantiated this suggestion.

We argue that SARS–CoV-2 may cause other surgical problems pertaining to inflammation. In addition, given its propensity to cause thromboembolic complications, bowel ischaemia is another distinct possibility. In keeping with this, acute pancreatitis, acute cholecystitis, gastrointestinal bleeding and bowel ischaemia have been reported in patients critically ill due to COVID-19 [7]. Another reported complication is haemorrhagic colitis [8]. Thus, a higher index of suspicion for surgical problems is required in patients with SARS–CoV-2 infection.

To our knowledge, this is the first report of SARS–CoV-2 gastrointestinal infection causing appendicitis. This adds to the body of evidence implicating SARS–CoV-2 in surgical complications. Given that SARS–CoV-2 has been discovered to affect multiple tissues, we propose that during the pandemic, biopsy and tissue specimens should be studied for the typical findings associated with COVID-19 and if present, specimens should be sent for detection via PCR.

[guanshentai]

Acid detection virus sampling tube automatic production line introduction about the use of virus sampling tube

　　GST acid detection virus sampling tube filling and capping packagingautomatic production lineequipment manufacturers introduce the use of virus sampling tubes!

　　Sampling using virus sampling tubes is mainly divided into oropharyngeal sampling and nasopharyngeal sampling:

　　1. Oropharyngeal sampling: first press the tongue with a tongue depressor, then insert the head of the sampling swab into the throat to wipe the bilateral pharyngeal tonsils and posterior pharyngeal wall, and wipe the posterior pharyngeal wall with mild force, avoiding touching the tongue department.

　　2. Nasopharyngeal sampling: measure the distance from the tip of the nose to the earlobe with a swab and mark it with your fingers, insert the sampling swab into the nasal cavity in the direction perpendicular to the nose (face), and the swab should be inserted at least half the length from the earlobe to the tip of the nose. Leave the swab in the nose for 15-30 seconds, swirl gently 3-5 times, and withdraw the swab.

　　It is not difficult to see from the method of use, whether it is an oropharyngeal swab or a nasopharyngeal swab, sampling is a technical task, which is difficult and easy to contaminate. The quality of the collected samples is directly related to the subsequent testing. If the viral load of the collected samples Low, easy to cause false negatives, difficult to diagnose.

　　Most of the samples recommended by the kits currently on the market are oropharyngeal swabs or nasopharyngeal swabs and bronchoalveolar lavage fluid. This can greatly reduce the difficulty of the samplers' work. After all, it is not difficult to collect venous blood samples, and like the detection of hepatitis C RNA, about 5 ml of EDTA anticoagulated blood samples are separated into plasma, and the extracted and purified RNA can fully meet the needs of PCR detection.

[stbiotech01]

How Oral Swabs Work?

Oral swabs are taken through the mouth. Oral swab tests are used to detect substance use. It’s also referred to as a saliva drug test or oral fluids drug test.

Oropharyngeal swab (oral swab) is the least invasive method which requires no needle poking or peeing in a cup. Oral swab tests can be done in few simple steps:

• A collection stick with an absorbent pad on one end is used to swab the inside of the cheek. • The sample is analyzed for traces of substances, either on-site or in a lab.

Oral swabs are having a relatively larger tip diameter, compared to nasal swabs. Although both can be used for specific uses, depending on the requirement.

These swabs are single-use sterilization product, which can only be used once. It shouldn’t be used if the package is destructed or damaged or beyond the expiration date.

St-Biotech manufactures and supplies different kinds of oral swabs depending on their usage and purpose. They are produced in highly sterilized areas to avoid any contamination. With a sterilized and dust free environment, high degree of cleanliness is maintained in order to provide highest purity in laboratory consumables.

[shelly-yanxia]

China factorty Throat swab oropharyngeal swab 

Material:ABS+Nylon

 Length:15.5cm 

Break point:8cm 

Package:paper bag 

Pharyngeal swab with SGS test report and CE FDA 

 sales2@mejoyhouse.com 

+8617818536156

[mcatmemoranda]

From UpToDate:

Diagnostic testing for urogenital gonorrhea in asymptomatic patients is generally the same as for symptomatic patients (ie, NAAT of first-catch urine for men and vaginal swab for women). Urethral Gram stain can also be used for men, although it is less sensitive in the absence of symptoms. Thus, if the Gram stain is negative in an asymptomatic man, NAAT should also be performed if gonorrhea is suspected due to risk factors. (See 'Men with urogenital symptoms' above and 'Women with urogenital symptoms' above.)

In addition, because of the significant prevalence of extragenital infections in MSM and the frequency of asymptomatic infections, routine screening for oropharyngeal and rectal gonorrhea is warranted in MSM [49]. Testing can be performed with NAAT on self-collected pharyngeal and rectal swabs. (See 'Performance on extragenital specimens' below.)

Diagnostic techniques include nucleic acid amplification testing (NAAT), culture, antigen detection, and genetic probes; microscopy is not useful for the diagnosis of chlamydia. Because of superior sensitivity and specificity and wide availability, NAAT is the diagnostic technique of choice.

If NAAT methods are unavailable, antigen detection and genetic probe methods can be applied to endocervical or urethral swabs to diagnose chlamydia. In resource-limited settings, rapid tests for chlamydia may be used for diagnosis, if available. When no specific diagnostic tests are available, the presumptive diagnosis of chlamydia is made when symptoms and signs of the clinical syndromes associated with chlamydia are present in young or sexually active patients.

Nucleic acid amplification testing (test of choice) — Nucleic acid amplification testing (NAAT) methodology consists of amplifying C. trachomatis DNA or RNA sequences using polymerase chain reaction (PCR), transcription-mediated amplification (TMA), or strand displacement amplification (SDA). These sensitive, specific tests have become the "gold standard" and are the preferred diagnostic method, if available [39,55].

Preferred specimens for testing — The preferred testing specimen varies by syndrome:

●Genitourinary infection or screening in females – Vaginal swab, which can be self-collected, is the specimen of choice. For females who are undergoing speculum exam (eg, for evaluation of symptomatic cervicitis or for routine Pap smear), NAAT can be performed on either endocervical (including cervical specimens collected into a liquid cytology medium for Pap screening) or vaginal swabs. A first-catch urine specimen is also acceptable in females but might detect up to 10 percent fewer infections when compared with vaginal and endocervical swab samples [55]. (See 'Test performance' below.)

●Genitourinary infection or screening in males – First-catch urine is the specimen of choice. NAAT can also be performed on a urethral swab.

●Rectal infection – NAAT can be performed on a rectal swab specimen [56]. Commercially available NAATs for C. trachomatis detect both lymphogranuloma venereum (LGV) and non-LGV C. trachomatis but cannot distinguish between them. Additional molecular procedures (eg, PCR-based genotyping) can be used to differentiate LGV from non-LGV C. trachomatis, but these are not widely available [55]. Although serology is useful in the diagnosis of classic LGV, its performance in the setting of LGV proctitis is suboptimal, and it is not recommended. Clinicians who suspect LGV proctitis should seek expert advice from local public health authorities and infectious disease specialists on how to diagnose the condition effectively. Often, this is not possible, and empiric therapy is warranted. (See "Treatment of Chlamydia trachomatis infection", section on 'Proctitis and rectal infection'.)

●Conjunctivitis – NAAT can be performed on conjunctival swabs to diagnose chlamydial conjunctivitis [57].

●Pharyngitis – Chlamydial pharyngeal infection is thought to be uncommon and generally not a target for diagnostic testing.

Swabs should have a plastic or wire shaft and a rayon, dacron, or cytobrush tip, as other materials may be inhibitory to the organism [55].

First-catch urine submitted for NAAT should be collected from the initial stream (approximately the first 10 mL) without pre-cleansing of the genital areas. Ideally, the patient should not have voided in the two hours prior to specimen collection. The performance of these is not affected by the presence of purulent material or blood [58]. (See 'Test performance' below.)

If non-NAAT-based testing is used for diagnosis or if adequate follow-up cannot be insured, patients with signs and symptoms consistent with chlamydia should be treated empirically before diagnostic test results return. (See "Treatment of Chlamydia trachomatis infection", section on 'Indications for empiric therapy'.)

[researchinhealthcare]

COVID-19 Sample Collection Kits Industry Drivers, Regional Analysis, Global Trends, Forecast to 2027

COVID-19 Sample Collection Kits Market Highlights :

According to MRFR analysis, the Global COVID-19 Sample Collection Kits Market is expected to register a CAGR of 5.20% during the forecast period of 2020 to 2027 and reach USD 4168.35 Million by 2027.

Sample collection usually takes place in a doctor’s room or in a testing laboratory collection center where there are trained specimen collectors who perform the testing services.

The growth of the global COVID-19 sample collection kits market can be contributed for the high demand of sample collection kits, due to the outbreak of COVID-19 globally, and approval of new and advanced detection tests by regulatory authorities.

Furthermore, a rise in the detection of antibodies, an increase in government funding, and a large volume of products & usage rate of swabs are also expected to boost the market growth during the forecast period.

However, a shortage of test-related supplies such as reverse transcription-polymerase chain reaction instruments, swabs, and virus control samples to control COVID-19, and lack of laboratory-based reagents are expected to restrain the growth of the global COVID-19 sample collection kits market.

Several market players such as Medline Industries, Inc., COPAN Diagnostics, and Becton, Dickinson, and Company, among others, currently dominate the global COVID-19 sample collection kits market.

COVID-19 Sample Collection Kits Market Regional Analysis :

The market has been divided, by region, into the Americas, Europe, Asia-Pacific, and the Middle East & Africa. The Americas region held the largest market in 2020, owing to the outbreak of COVID-19 in the region. The COVID-19 sample collection kits market in the Americas has further been branched into North America and Latin America, with the North American market divided into the US and Canada.

The European COVID-19 sample collection kits market has been categorized as Western Europe and Eastern Europe. The Western European market has further been classified as Germany, France, the UK, Italy, Spain, and the rest of Western Europe.

The COVID- 19 sample collection kits market in Asia-Pacific has been segmented into China, India, Japan, Australia, South Korea, and the rest of Asia-Pacific. The Asia-Pacific region is expected to be the fastest-growing region. The COVID -19 sample collection kits market in the Middle East & Africa has been divided into the Middle East and Africa.

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COVID-19 Sample Collection Kits Market Segmentation :

The global COVID-19 sample collection kits market has been segmented based on the product type, application, and end user.

On the basis of product type, the market has been segmented into swabs, viral transport media, blood collection kits, and others. The swabs segment is anticipated to be the fastest-growing segment. The swab segment is further divided into nasopharyngeal swabs and oropharyngeal swabs. The Centers for Disease Control and Prevention (CDC) has recommended collecting only nasopharyngeal swabs for testing the sample. The viral transport media is the largest growing segment.

Based on application, the market has been segmented into diagnostic, and research. The diagnostic segment is expected to be the fastest-growing, while the research segment is the largest growing segment.

The market based on end user has been segmented into hospitals & clinics, diagnostics centers, and others. The diagnostic center is anticipated to be the fastest-growing segment. The largest growing segment is hospitals & clinics.

COVID-19 Sample Collection Kits Market Key Players :

Some of the key players in the global COVID-19 sample collection kits market are Thermo Fisher Scientific, Inc. (US), Hardy Diagnostics (US), BNTX Inc. (Germany), Formlabs (US), Medline Industries, Inc. (US), HiMedia Laboratories (India), VIRCELL S.L. (Spain), Puritan Medical Products (US), COPAN Diagnostics (California), Becton, Dickinson, and Company (US), Laboratory Corporation of America Holdings (US), Lucence Diagnostics Pte Ltd. (California)

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[houseofdiagnostics]

Book Your RT-PCR Test For Covid In Delhi

To date, seven identified coronaviruses (CoVs) have been found to infect humans; of these, three highly pathogenic variants have emerged in the 21st century. The newest member of this group, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first detected at the end of 2019 in Hubei province, China. Since then, this novel coronavirus has spread worldwide, causing a pandemic; the respiratory disease caused by the virus is called coronavirus disease 2019 (COVID-19).

The clinical picture ranges from asymptomatic, through mild respiratory tract infections and influenza-like illness (mainly fever, cough, and fatigue), to severe disease with accompanying lung injury, multiorgan failure, and death.

The following specimens can be collected for Real Time RT PCR Test (Reverse Transcriptase).

UPPER RESPIRATORY TRACT: Nasopharyngeal swab specimen (NPS)  /Oropharyngeal swab (OP) (throat) specimen /Anterior nasal specimen

Nasopharyngeal wash/aspirate or nasal wash/aspirate

LOWER RESPIRATORY TRACT: Bronchoalveolar lavage, tracheal aspirate, pleural fluid, lung biopsy.

We at HOD are performing automated extraction followed by Real time RT PCR using QUANTSTUDIO 5 instrumentOur turnaround time is 24 hours.

We are using recommended biosafety precautions while collecting the specimens.

We are implementing all quality measures to ensure that correct report is delivered.

home collection rt pcr test