#oral pills to prevent covid
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I just bought myself a manga about the artist going through severe illness and I found it comforting to read someone else's experience, so I thought maybe I would share a little about my experience with MCAS again. so here's all the pills I take!
cromolyn. 2 ampules mixed with water 4x/day (although I'm often out of bed for 12 hours or less and have trouble keeping track of time, so often it's 3x instead). mast cell stabilizer.
multivitamin. I only took this for a week so far and stopped to gather data. (my paranoia was getting bad, which often means I'm reacting to a med. this is a cheap one with many fillers.) meant to make up for difficulty accessing food and possible malabsorption.
fludrocortisone. 2 pills a day. for POTS.
atenolol. 1 per day. also for POTS.
montelukast. 1 per day. technically for asthma, but works by blocking one of the signals the mast cells send.
loratadine (aka claritin). 1 pill 2x/day, which we had to fight the insurance about after a while. antihistamine, meant to prevent anaphylaxis by blocking a different mast cell signal.
aspirin. 2 pills 2x/day. to reduce inflammation and control chronic pain.
whichever oral hormonal birth control my insurance will give me (it varies). 1 per day. menstruation makes my MCAS flare and I still have incomplete cessation even after an ablation, so I keep taking it even when not putting myself at risk of pregnancy.
dye-free diphenhydramine (aka benadryl). another antihistamine, taken when my MCAS flares to reduce or completely end the symptoms. (the pink dye in the regular formulation is actually a very common trigger.)
low-dose prednisone. steroid kept on hand for unavoidably high-demand occasions (like moving across the country) or unshakable prolonged flares (like, a week).
that's 8 pills in the morning, 3-4 at night, 8 ampules in the day, and 2 different emergency meds. plus I try to drink a gatorlyte every day (also good for POTS and certain mineral shortages) and try to avoid triggers (including heat, stress, and overexertion -n- )
3 and 4 were the first meds that ever made me feel any better, before we'd figured out it was MCAS. (likely with secondary POTS/EDS.) 6 and 7 are the first line treatment for MCAS, they're the first medications I actually took *for* it. they are often used in combination with famotidine (aka pepcid) but that made my paranoia super bad so I stopped taking that one.
this was my regimen established before I got covid last july, which made my MCAS much worse, which also made it impossible to get a new doc post-move since I can't physically get to an appt. so this is likely to change once I have medical care again. being sick is a lot of work!
#kirby#daily kirby#my art#digital#hal laboratory#nintendo#chronic illness#mcas#tmi#long post#ask to tag#(the manga was 'I'm a terminal cancer patient but I'm fine' btw)#(I don't have cancer as far as we know! and my illness wouldn't be qualified as terminal!)#(it's a chronic illness that's gotten pretty severe and has the potential to be fatal tho.)#(thebibliosphere has mcas too and she spent much of 2019 at death's door before she finally got knowledgeable care just in time.)#(at least I think it was 2019. I can't remember for sure.)#(anyway 'terminal' is a squishy and suspect category - even the mangaka says in the afterword she's stopped using it)#(cuz at time of publication she'd gone into remission! very exciting for her :> )#(she did unfortunately pass away a couple months ago but. such is life.)#(it can still be a nice book ending even if it didn't last.)#(also yes. my christmas tree is still up in february. I've Been Very Ill.)#(I've gotten all the ornaments off (over the course of a week) and I just have to take off the colored lights and disassemble it.)#(I've been using it for ambient light in the living room because I was really photosensitive for a few months.)#(it's not as bad now but I still prefer diffuse light for sure.)#favorites
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URGENT: COVID-19 DRUG SHORTAGE
Manchester, United Kingdom
24 January 2024
As the resurgence of the COVID-19 virus shows no sign of fading, NHS staff continue to work tirelessly to be at the beck and call of patients.
However, it has come to the attention of the NHS staff that there is soon to be a shortage of the drug Paxlovid. An oral antiviral pill, it is recommended to be taken within five days of experiencing symptoms to reduce the chances of hospitalisation. Given the everlasting waiting lines at hospitals, such medication would be quintessential, and in fact, strategic to reduce the burden on NHS staff. More COVID-19 patients can be treated at home, and will not require hospitalisation.
The NHS staff have voiced their concerns to Amanda Pritchard, CEO of the NHS. They only had one request: To obtain more of the medication.
However, given the extremely tight budget, the CEO has declined to allow this request. Instead, funds are being diverted to the Critical Care Unit, to get more resources for patients that are critically ill, including COVID-19 patients at their last breath.
The NHS staff finds this extremely ironic. Is prevention not better than cure?
Once again, the NHS has failed to allocate funds efficiently.
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Intrauterine Devices Market Size, Share, Trends Analysis with Forecast 2021- 2031 | Mona Lisa NV (Germany), Pregna International Limited (India)
The global Intrauterine Devices Market was valued at US$ 3.0 billion in 2021 and it is anticipated to grow up to US$ 4.4 billion by 2031, at a CAGR of 3.9% during the forecast period.
An Intrauterine device is a T-shaped plastic or copper birth control medical device inserted into the uterus to prevent pregnancy. It releases copper into the womb, altering the cervical mucus and making it difficult for sperm to reach and survive an egg. It can also prevent a fertilized egg from implanting itself. IUDs are widely preferred over other methods of contraception because they are compact, safe, and cost-effective, and they have no hormonal side effects such as acne, headaches, or breast tenderness. It is currently available in various types that can last for a period of 5 to 10 years.
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Market Drivers and Trends
The rise in awareness over the availability of the devices through campaigns is the primary driver of the industry’s growth. One of the key factors influencing global demand for IUDs are initiatives taken by various countries’ health agencies, in collaboration with non-profit organizations (NPOs), to raise awareness about family planning, the benefits of birth control measures, and health-related issues caused by unplanned pregnancies are promoting market growth. Furthermore, because IUDs have a very low risk of ectopic pregnancy, they are gaining popularity among nulliparous women and adolescents who have never given birth and are at a higher risk for negative birth outcomes such as breast and reproductive cancers.
Furthermore, the rise in unplanned and unwanted pregnancies, which has become one of the world’s major concerns. For Instance, according to the World Health Organization (WHO) and the International Federation of Medical Students’ Associations’ 2018 report, approximately 22 million unsafe abortions are performed globally each year, resulting in the deaths of an estimated 47,000 women, Aside from that, the development of advanced product variants with fewer side effects, such as postpartum, slimmer, and reusable IUDs, is expected to offer lucrative growth opportunities to industry investors in the coming years. These factors are expected to drive the growth of the global Intrauterine Devices Market.
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COVID-19 Impact
The COVID-19 pandemic had a significant impact on the market, because the intrauterine devices market is heavily reliant on physician-administered and physician-prescribed intrauterine devices, the number of patient visits for contraception in hospitals has decreased. However, restrictions on physician office visits without an emergency were imposed during the first few months of the ongoing pandemic. Half of the population considering family planning during COVID-19 shifted their interest from intrauterine devices to other contraception methods such as contraception pills, resulting in a worldwide decline in demand for intrauterine device products. The Health Management Information System, which is part of the Health Ministry’s 2020 union, reported that the rate of intrauterine device insertion decreased by 21% during the COVID-19.
According to a research study by Anita Makins, which was published in Gynecology & Obstetrics Journal May 2020, states that there is an huge stock-out of contraceptive methods during the COVID-19 pandemic 2020. Furthermore, the United Nations Population Fund predicted that 46 countries that typically receive supplies from them has experienced stock-outs of one or more modern methods, which includes copper intrauterine devices, implants, oral contraceptive pills, and condoms, over the next six months beginning in May 2020.
Global Intrauterine Devices Market Segmentation
By Type
Copper
Hormonal
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By End-User
Hospitals
Clinics
Community Healthcare Centers
Others
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How Do COVID-19 Antiviral Pills Work & Who Is Eligible to Receive Them
COVID-19 was a globally spreading pandemic, and since it is a new species of virus, it doesn't have any proper treatment or medicine. However, now most people are vaccinating as a precautionary measure to avoid the coronavirus risk.
Besides all of the vaccines, there's a chance that you can have this virus; however, that chance is meagre. Similarly, now biologists have discovered many other antiviral drugs for Corona.
But do you know that you can only prevent the virus attack by consuming some pills? Yes, and here I will tell you How COVID-19 Antiviral Pills Work & Who Is Eligible to Receive Them?
Eligibility to Orally Consume Anti-COVID Pills
The medicines for COVID-19 are usually not accessible without a doctor's prescription. For the following purpose, the two standard tablets used are called Ritonavir Paxlovid.
Moreover, its best and most affordable alternative is Paxzen, a generic version of the respective medicine.
Both of these medicines have different eligibility criteria; however, it also depends on the condition and age of the patient. Similarly, it would be best if this medication is used only after the advice of a doctor.
Paxzen is Suitable for:
Older than 12 years old, having a weight of a minimum of 88 pounds.
Those who have tested positive for COVID-19 and those with a high risk of rapid viral growth can take this medicine for cure.
Molnupiravir is Effective for:
Patients having severe development of the virus should use this.
Children below 18 are not allowed to consume this drug.
If the doctor suggests you this to them, you can use them.
Why are These Two Medicines Distinct from Each Other?
Besides the similar purpose, both medicines are still slightly different in working. Both are very effective for preventing Corona and its symptoms; however, the conditions to consume it also vary.
Paxlovid is taken with two more medicines and only then works effectively. These two pills are named Nirmatrelvir and Ritonavir.
Both are prescribed by doctors in combination, where one prevents replication of the virus, and the other supports Nirmatrelvir Tablets from breaking down until their work is finished. Studies on this medication set show that it has reduced almost 90% of Corona cases from hospitalization.
Similarly, the other medicine is given with a combination of four other tablets. It also prevents the virus from replicating; however, these are taken every 12 hours for five days.
Which One is the Best Medicine?
Paxzen Tablet is the best medicine for COVID 19and it is also readily available. This drug is produced by Zenara Pharma, a very well-known pharmaceutical in India.
It is also available easily from any medical store, online or offline. Moreover, you can Buy Paxzen Tablets at a very reasonable price.
It has 30 medicines in total, which includes combination medicines of 20 & 10, respectively. Each box is bought for a maximum of 4800 INR. Similarly, as compared to Pfizer's drugs is 70% cheaper.
You can buy the substitute of Paxzen Tablet from 24x7 Pharma which is Primovir 150 mg, Movfor 200 mg and so on.. Just check it out.
Are There Any Harmful Side Effects of Paxzen?
Common Side Effects
Every strong antiviral medicine has some mild side effects, and so as this medicine has. Usual side effects of Paxzen include:
Diarrhoea & change in taste
Increased blood pressure
Slightly muscle pain
You don't have to worry if you have any of these side effects; however, you may need help if these symptoms last longer.
Rare Side Effects
Some rare side effects that need immediate medical help are:
Serious Allergic reactions
Itching & Swelling
Severe dizziness
Breathlessness
Swelling of face, tongue, throat
These are the side effects discovered by doctors to date. However, there might be more conditions, so if anyone has any symptoms, they should discuss them with their doctor.
The medication should be stopped if any of the symptoms are found in the patient; otherwise, it can worsen. Moreover, you can treat these side effects if treated on time, so don't ignore them.
Do I Still Need to Take Pills When I Don't Have Symptoms?
One of the most common mistakes is that people don't start treatment as soon as they are tested positive and wait for the symptoms to be shown. However, no one should wait for treatment if he's tested positive for Corona because early treatment can reduce health loss.
Since the virus replicates rapidly, it is perilous to wait for the symptoms. However, the reason for not feeling symptoms can be because you have better immunity, so the virus couldn't damage much, but it can become severe if not treated.
Doctors also suggest you get treated as soon as you get the test results, even when you don't feel sick. Similarly, it will be good for your health if you call for early treatment to recover faster from the immunity damage.
Is There Still a Need to Get Vaccinated?
These oral medicines can never work as a vaccine because these cannot be consumed as a precautionary measure. Vaccination is essential even when you're not tested positive because it will reduce the risk of getting attacked by the virus and strengthen your immunity.
Similarly, pills are not post-exposure prevention of Corona. There's no medicinal alternative to the vaccine, and there are many conditions for taking pills; therefore, unlike COVID-19, they are not suitable for everyone. Furthermore, you can take a vaccine even after you are attacked by the disease.
Although there are many rumours about vaccination, and you may be hesitant to get one, please ensure that the information is accurate and do some research. You can also consult your doctor if you are still avoiding vaccination.
Bottom Line
No doubt medicines are very effective but only when you are infected, not before. Similarly, COVID-19 vaccination is a must, and no one should avoid it. Protect yourself and your family, and vaccinate to prevent health issues.
As it is said, "Prevention is better than cure", so we should not wait for the virus to attack, and beforehand, we should take precautionary measures. However, research shows that an unvaccinated person is twice as likely to be infected by coronavirus than those vaccinated.
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করোনা চিকিৎসায় বড়ির যুগ শুরু
খুব সাধারণ খাওয়ার বড়ি যদি কোভিড সারিয়ে তুলতে পারে, তবে কেমন হয়? যুক্তরাষ্ট্রের ওষুধ প্রস্তুতকারক প্রতিষ্ঠান মার্ক ও ফাইজার এ রোগের চিকিৎসায় মুখে খাওয়ার বড়ির পরীক্ষায় উৎসাহব্যঞ্জক ফলাফল পেয়েছে। এ ছাড়া বিষণ্নতাপ্রতিরোধী এক ওষুধও কোভিড চিকিৎসায় ভালো ফল দেখিয়েছে।
বার্তা সংস্থা এএফপি এসব তথ্য জানিয়ে বলেছে, মুখে খাওয়ার এ বড়ি মহামারির বিরুদ্ধে লড়াইয়ে একটি নতুন অধ্যায় খুলতে পারে।
এটা কী ধরনের চিকিৎসা?
কোভিড-১৯–এর উপসর্গ দেখা দেওয়ার সঙ্গে সঙ্গেই মুখে খাওয়ার এই বড়ি গ্রহণ শুরু করতে হয়। এতে গুরুতর অসুস্থতা ও হাসপাতালে ভর্তি হওয়ার বিষয়টি এড়ানো সম্ভব। বিশ্বজুড়ে করোনা মহামারি শুরুর পর থেকেই এ ধরনের ওষুধের জন্য অপেক্ষা করা হচ্ছিল। কয়েক মাস ধরে গবেষণার পর মার্ক ও ফাইজার কাঙ্ক্ষিত লক্ষ্যে পৌঁছাতে পেরেছে।
গত অক্টোবরের শুরুতে মার্ক কর্তৃপক্ষ বলেছিল, করোনার চিকিৎসায় তারা মলনুপিরাভির নামের বড়ি ব্যবহারের জন্য যুক্তরাষ্ট্রের ওষুধ প্রশাসনের কাছে অনুমোদন চেয়েছিল। আর গত শুক্রবার ফাইজার অনুমোদন চাওয়ার বিষয়টি উল্লেখ করেছে। এই দুই কোম্পানির ওই বড়ি অ্যান্টি-ভাইরাল বা ভাইরাসপ্রতিরোধী হওয়ায় তা ভাইরাসের অনুরূপ সৃষ্টির বিষয় কমিয়ে দিতে পারে। এতে রোগ ছড়িয়ে পড়ার গতি কমে আসে। দুটি কোম্পানির পক্ষ থেকেই ক্লিনিক্যাল ট্রায়ালে অত্যন্ত ভালো ফল পাওয়ার দাবি করা হয়েছে। এতে রোগীর হাসপাতালে ভর্তি হওয়ার ঝুঁকি অনেকটাই কমতে দেখা গেছে।
পরীক্ষায় দেখা গেছে, মলনুপিরাভিরের কার্যকারিতা যাচাইয়ে ৭৭৫ জন রোগীর ওপরে একটি গবেষণা চালায় মার্ক। সেখানে দেখা যায়, যেসব রোগীর চিকিৎসায় এটি ব্যবহার করা হয়েছে, তাঁদের মধ্যে মাত্র ৭ দশমিক ৩ শতাংশকে হাসপাতালে ভর্তি হতে হয়েছে।
আর এটি গ্রহণ করা কোনো রোগী মারা যাননি। এদিকে প্যাক্সলোভিড বড়ি গ্রহণকারীদের ক্ষেত্রে হাসপাতালে ভর্তি হওয়ার ঝুঁকি ৯০ শতাংশ পর্যন্ত কমেছে বলে দাবি করেছে ফাইজার। তবে মার্ক ও ফাইজারের বড়ির সরাসরি তুলনা করা ঠিক হবে না। কারণ, দুই কোম্পানির ক্লিনিক্যাল ট্রায়ালের নিয়মনীতি ছিল আলাদা।
এদিকে বাজারে থাকা ফ্লুভক্সামিন নামে বিষণ্নতাপ্রতিরোধী ওষুধ ব্যবহারেও কোভিড রোগীদের চিকিৎসার ক্ষেত্রে আশাব্যঞ্জক ফল পাওয়ার দাবি করেছেন গবেষকেরা। গত অক্টোবর মাসে ব্রাজিলের গবেষকেরা এ–সংক্রান্ত নিবন্ধ প্রকাশ করেছেন ‘ল্যানসেট গ্লোবাল হেলথ’ নামের সাময়িকীতে।
মুখে খাওয়ার বড়ি কেন গুরুত্বপূর্ণ?
কোভিড ঠেকাতে মুখে খাওয়ার বড়িগুলোর কার্যকারিতা যদি নিশ্চিত করা যায়, তবে তা মহামারি মোকাবিলায় গুরুত্বপূর্ণ পদক্ষেপ হয়ে উঠতে পারে। করোনাভাইরাসের সংক্রমণ ঠেকাতে টিকার পাশাপাশি মুখে খাওয়ার বড়িও গুরুত্বপূর্ণ থেরাপি হিসেবে ব্য��হৃত হবে। বর্তমানে করোনার যে চিকিৎসা পদ্ধতি ��য়েছে, তার বেশির ভাগই সিনথেটিক অ্যান্টিবডি আকারে। তবে এ ধরনের অ্যান্টিবডি চিকিৎসা কেবল গুরুতর অসুস্থ ব্যক্তিদের ক্ষেত্রে প্রয়োগ করা হয়। আর মুখে খাওয়ার বড়ি সহজেই বাড়িতে বসে গ্রহণের জন্য পরামর্শ দিতে পারবেন চিকিৎসকেরা।
মার্ক ও ফাইজারের তৈরি করা বড়িতে এখন পর্যন্ত গুরুতর কোনো পার্শ্বপ্রতিক্রিয়া দেখা যায়নি। পাঁচ দিনে ১০টি বড়ি গ্রহণ করতে হয় রোগীকে।
ব্রিটিশ ভাইরোলজিস্ট স্টিফেন গ্রিফিন বলেন, ‘এই ওষুধের সাফল্য সার্স কোভ-২ সংক্রমণের গুরুতর পরিণতি প্রতিরোধ করতে একটি নতুন যুগের সূচনা করবে।’
সীমাবদ্ধতা কী কী?
মার্ক ও ফাইজার এখন পর্যন্ত কেবল বড়ির কার্যকারিতা নিয়ে বিবৃতি প্রকাশ করেছে। তাদের ক্লিনিক্যাল ট্রায়ালের তথ্য এখনো সামনে আনেনি। তাই তাদের বড়ি দিয়ে চিকিৎসার বিষয়টি ঠিক ঠিক মূল্যায়ন করা এখনই কঠিন।
ফ্রান্সের সংক্রামক রোগ বিশেষজ্ঞ কারিন ল্যাকোম্ব গত সেপ্টেম্বরে সতর্ক করে বলেছিলেন, যত দিন পর্যন্ত গবেষণা মূল্যায়ন না করা হয়, তত দিন পর্যন্ত এ ধরনের প্রতিষ্ঠানের ঘোষণা সতর্কতার সঙ্গে নেওয়া উচিত। এ ধরনের চিকিত্সা ফার্মাসিউটিক্যাল গ্রুপগুলোর জন্য সম্ভাব্য বাজার সৃষ্টি করে থাকে।
অবশ্য মার্ক ও ফাইজারের ক্ষেত্রে কিছু তথ্য শুধু প্রতিশ্রুতি বলে মনে হচ্ছে না। তারা গবেষণার ক্ষেত্রে যথাযথ নিয়ম মেনেছে। স্বতন্ত্র পর্যবেক্ষণ কমিটি তা মূল্যায়ন করেছে। ফ্লুভক্সামিনের ক্ষেত্রে তথ্য সহজলভ্য হলেও তা নিয়ে সমালোচনা রয়েছে।
কখন বাজারে আসবে?
গত বৃহস্পতিবার করোনায় আক্রান্ত ব্যক্তির চিকিৎসায় প্রথমবারের মতো ‘মলনুপিরাভির’ বড়ি ব্যবহার করার বিষয়ে অনুমোদন দিয়েছে যুক্তরাজ্যের ওষুধ নিয়ন্ত্রক সংস্থা। করোনায় আক্রান্ত ঝুঁকিপূর্ণ রোগীর ক্ষেত্রে মলনুপিরাভির বড়ি দিনে দুবার প্রয়োগ করতে হবে বলে জানা গেছে।
যুক্তরাজ্যের স্বাস্থ্যমন্ত্রী সাজিদ জাভিদ বলেন, যেসব ব্যক্তি দুর্বল ও যাঁদের রোগ প্রতিরোধক্ষমতা কম, তাঁদের ক্ষেত্রে এই চিকিৎসা এক যুগান্তকারী পদক্ষেপ। এক বিবৃতিতে তিনি বলেছেন, ‘আমাদের দেশের জন্য আজ এক ঐতিহাসিক দিন। কেননা, বিশ্বে এখন যুক্তরাজ্যই প্রথম দেশ, যেখানে কোভিডের চিকিৎসায় একটি অ্যান্টিভাইরাল ওষুধ ব্যবহারের অনুমোদন দেওয়া হলো।’
যুক্তরাজ্যের ওষুধ নিয়ন্ত্রক সংস্থা এমএইচআরএ বলেছে, যাঁদের মৃদু থেকে মধ্যম ধরনের করোনার উপসর্গ রয়েছে ও জটিলতার মুখে পড়ার অন্তত একটি ঝুঁকিপূর্ণ উপাদান যেমন স্থূলতা, বেশি বয়স, ডায়াবেটিস বা হৃদ্যন্ত্রের অসুখ রয়েছে, তাঁদের ওপর এ ওষুধ প্রয়োগের অনুমোদন দেওয়া হয়েছে।
যুক্তরাষ্ট্র ও ইউরোপিয়ান ইউনিয়নের (ইইউ) স্বাস্থ্য কর্তৃপক্ষও জরুরিভাবে ওষুধটি পর্যালোচনা করছে। ইউরোপিয়ান মেডিসিন এজেন্সি বৃহস্পতিবার বলেছে, তারা দ্রুত বিষয়টি পর্যালোচনা করবে। তবে তারা নির্দিষ্ট সময় উল্লেখ করেনি। ইতিমধ্যে বেশ কয়েকটি দেশ ‘মলনুপিরাভির’ বড়ির ফরমাশ দিয়েছে। এর তালিকায় শীর্ষে রয়েছে যুক্তরাষ্ট্র। দেশটি প্রথম দফায় ১৭ লাখ কোর্সের বড়ির ফরমাশ দিয়েছে। এক একজনের পাঁচ দিনের কোর্সের জন্য বড়ির দাম পড়ছে ৭০০ মার্কিন ডলার। ফাইজারের প্যাক্সলোভিড বড়ির দাম এখনো জানা যায়নি। তবে তারা সাশ্রয়ী মূল্যে ওষুধ সরবরাহ করার প্রতিশ্রুতি দিয়েছে।
ইতিমধ্যে বেশ কয়েকটি দেশ ‘মলনুপিরাভির’ বড়ির ফরমাশ দিয়েছে। এর তালিকায় শীর্ষে রয়েছে যুক্তরাষ্ট্র। দেশটি প্রথম দফায় ১৭ লাখ কোর্সের বড়ির ফরমাশ দিয়েছে। এক একজনের পাঁচ দিনের কোর্সের জন্য বড়ির দাম পড়ছে ৭০০ মার্কিন ডলার। ফাইজারের প্যাক্সলোভিড বড়ির দাম এখনো জানা যায়নি। তবে তারা সাশ্রয়ী মূল্যে ওষুধ সরবরাহ করার প্রতিশ্রুতি দিয়েছে।
ভাষান্তর: মিন্টু হোসেন
#Corona treatment oral pills#Corona treatment#Covid19#corona#coronatreatment#oral pills to prevent covid#Covid 19#মুখে খাওয়ার বড়ি#করোনা চিকিৎসায় বড়ি#করোনা চিকিৎসায় মুখে খাওয়ার বড়ি
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Fourteen out of 15 severe COVID-19 patients who were treated in an investigator-initiated interventional open-label clinical study of the drug TriCor (fenofibrate) didn’t require oxygen support within a week of treatment and were released from the hospital, according to the results of a new Hebrew University of Jerusalem study. Fenofibrate is an FDA-approved oral medication. The results were published on Researchsquare.com and are currently under peer review. Specifically, the team that was led by HU’s Prof. Yaakov Nahmias carried out the study at Israel’s Barzilai Medical Center in coordination with the hospital’s head of the Infectious Disease Unit, Prof. Shlomo Maayan, and with support from Abbott Laboratories. The 15 treated patients all had pneumonia and required oxygen support. They were also older with multiple comorbidities, ranging from diabetes and obesity to high blood pressure.I n addition to standard of care, the patients were given 145 mg/day of fenofibrate for 10 days. “The results were dramatic,” Nahmias told The Jerusalem Post. “Progressive inflammation markers, which are the hallmark of deteriorative COVID-19, dropped within 48 hours of treatment. Moreover, 14 of the 15 severe patients didn’t require oxygen support within a week of treatment.” The 15th patient was off oxygen within 10 days.
When looking at the data on other similar severe patients, less than 30% of them on average are removed from oxygen support within a week. In other words, fenofibrate could dramatically shorten the treatment time for severe COVID patients. “We know these kinds of patients deteriorate really fast, develop a cytokine storm in five to seven days and that it can take weeks to treat them and for them to get better,” Nahmias said. “We gave these patients fenofibrate and the study shows inflammation dropped incredibly fast. They did not seem to develop a cytokine storm at all. ”Cytokine storms are aggressive inflammatory responses to illness.
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In general, patients who do not require oxygen can be treated at home,” he said. “Additionally, despite the high number of COVID deaths in Israel and abroad, the majority of severely sick patients survive.“ If you look over a 28-day period, I would have expected all of them to survive with or without the drug,” Nahmias explained. “The question is how fast we can get them home or how quickly we can get a severe patient to a mild condition.” All of the patients completed a 10-day home treatment after discharge and, according to Maayan, “no drug-related adverse events” were reported. FENOFIBRATE WAS approved by the FDA back in 1975 for long-term use and is considered safe. Moreover, it is an inexpensive pill, Nahmias said. It costs less than $1.50 a day, meaning the entire treatment per patient was around $15. Nahmias has been studying the use of fenofibrate for treating COVID-19 almost since the start of the pandemic. He first ran a pre-clinical trial and then a multi-center retrospective study, both of which supported the effectiveness of the drug. “Viruses are parasites,” Nahmias explained. “They cannot replicate by themselves. They have to get inside a human cell and hijack their machinery to replicate. ”Working with collaborators in the United States, Nahmias demonstrated that the coronavirus prevents the burning of fat in lung cells, resulting in large amounts of fat accumulating inside lung cells – a condition the virus needs to reproduce. Fenofibrate, he hoped, would reverse that effect, and eliminate virus replication. “By understanding how the SARS-CoV-2 controls our metabolism, we can wrestle back control from the virus and deprive it of the very resources it needs to survive,” Nahmias told the Post, noting that this also may help explain why patients with high blood sugar and cholesterol levels are often at a particularly high risk to develop COVID-19. The professor is now involved with a series of Phase III studies being carried out in South America, the United States and Israel. Those studies are placebo-controlled and double-blind. Nahmias said his team had been struggling to get patients enrolled in the study before the onset of the Delta variant, but efforts are now progressing more rapidly. He hopes that results could be available as early as within the next two months.In the meantime, the drug is available, and physicians can decide to give treatment with it based on available data. “There are no silver bullets,” he said, “but fenofibrate is far safer than other drugs proposed to date, and its mechanism of action makes it less likely to be variant-specific. ”In the meantime, the drug is available, and physicians can decide to give treatment with it based on available data. “There are no silver bullets,” he said, “but fenofibrate is far safer than other drugs proposed to date, and its mechanism of action makes it less likely to be variant-specific.”
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Pfizer's Covid antiviral pill may cut severe illness by 89 percent
The drugmaker said its studies of the pill were so successful that it stopped clinical trials early.
The drugmaker Pfizer said Friday that clinical trials of its experimental Covid-19 pill have been so successful in preventing people from becoming hospitalized or dying from the virus, that it's stopping the studies early in the hope that the general public might benefit.
The antiviral pill, which is combined with a low dose of an HIV drug called ritonavir, can reduce hospitalizations or deaths from Covid-19 by up to 89 percent among high-risk patients, Pfizer said in a news release.
High-risk patients include the elderly, as well as people with underlying health conditions, such as obesity or type 2 diabetes.
Full coverage of the Covid-19 pandemic
Albert Bourla, Pfizer’s chief executive, called the drug a potential “game-changer” in a statement.
“These data suggest that our oral antiviral candidate, if approved by regulatory authorities, has the potential to save patients’ lives, reduce the severity of Covid-19 infections, and eliminate up to nine out of ten hospitalizations.”
Pfizer only released its data in a press release; it did not publish the full data from the clinical trial. Dr. John Sanders, chief of infectious diseases at Atrium Health Wake Forest Baptist in North Carolina, said it will be important for outside experts to pore over and scrutinize the results.
Still, Sanders called the preliminary information “remarkable.”
“The availability of an oral antiviral that can reduce the risk of hospitalization and death in high risk patients by 89 percent will have a major impact on how we treat Covid-19,” he wrote in an email to NBC News.
Early diagnosis of Covid-19 would be key. Pfizer said that its antiviral was most effective within the first three days of symptoms. Side effects, according to Pfizer, were mild to moderate, and comparable to those who got the placebo.
The results were so significant, Pfizer said that it would “cease further enrollment into the study due to the overwhelming efficacy demonstrated," and planned to ask the Food and Drug Administration to authorize the drug combination “as soon as possible.”
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Pfizer started Anti-Covid Pill Trials
Many nations are actively urging their citizens to get vaccinated against Covid-19. Because it is currently the most effective method of protecting ourselves and others around us from the virus. The question is, what happens if you contract Covid-19 despite having vaccinated? Pfizer is taking a deeper look at anti Covid pill as a result of recent clinical trials conducted by the company.
In a recent announcement, the pharmaceutical company stated that they had initiated a middle-to-late stage clinical research for anti-Covid medications. Those who have been expose to the virus might take these pills orally to combat the illness. The idea is that it would be similar to other oral medications, such as Tamiflu, which has consumed by people who are suffering from influenza.
It has claimed to aid in the prevention of the condition advancing and getting more severe. Which is similar to what the vaccination has intended to accomplish. To fight against the virus, according to Pfizer’s chief scientific officer Michael Dolsten, “we believe effective treatments for those who have contracted, or have been expose to, the virus will be require in addition to the influence that vaccinations have had on the virus’ spread.”
The Anti Covid pill made by Pfizer has also known as a protease inhibitor. And it has intended to aid in the prevention of the virus from multiplying. The business began developing the medicine in March 2020, and the current trial will involve 2,660 adults. And will be use to evaluate the drug’s safety and efficacy, among other things.
Read Also:
Punjab is experiencing an outbreak of dengue disease
Published in Lahore Herald #lahoreherald #breakingnews #breaking
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Sarm Hippique.
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IUPAC-IUB Joint Commission on Biochemical Nomenclature, Conformational language for five and also six-membered ring types of monosaccharides and also their derivatives. For the sake of harmony, the area of replacement must be created as above based on Haworth's depiction of the pyranose framework of monosaccharides, in example with the glycogen particle.
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CohBar Announces Preclinical Collaboration with NIAID to Evaluate Potential of CB5064 Analogs for Treatment of COVID-19 ARDS - StreetInsider.com
CohBar Announces Preclinical Collaboration with NIAID to Evaluate Potential of CB5064 Analogs for Treatment of COVID-19 ARDS.
Posted: Mon, 11 Jan 2021 14:05:37 GMT [source]
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In this test, 250 individuals with osteoarthritis of the knee were randomised to get either 10 g collagen hydrolysate or a sugar pill daily for 6 months. This test consisted of 389 people with osteoarthritis throughout 20 websites in the UK, USA and Germany. Individuals were randomised to get either 10 g of collagen hydrolysate or placebo tablets for 24 weeks. Kind II collagen showed less puffy joints, joint tenderness and also much better walk time in just one of the trials versus a sugar pill.
Glycoproteins where the sialic acid has actually been eliminated are designated by the prefix asialo-, e.g. asialo-α1-acid glycoprotein, and also asialofetuin. Removal of both sialic acid and also galactose lead to asialo-agalactoglycoproteins. pharmalabglobal online 99% Purity AOD , collagen, fish antifreeze glycoproteins as well as potato lectin are O-glycoproteins (or O-glycosylproteins). Writers adding to RSC publications do not need to formally request consent to recreate material contained in this write-up supplied that the correct recognition is supplied the replicated product. If you are not the writer of this write-up as well as you desire to recreate material from it in a 3rd party non-RSC magazine you have to officially request authorization utilizing Copyright Clearance Facility. Most likely to our Instructions for making use of Copyright Clearance Facility web page for details. A sheer, radiance-boosting evening cream that keys skin against contamination while you rest.
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An astronaut got a blood clot in space – now our study shows how to best protect crew
by Varsha Jain
Astronaut Peggy Whitson at the International Space Station in 2016. NASA, CC BY-SA
You are locked inside and are encouraged to do one hour of physical exercise per day. You are isolated from the people you love, and there are limited forms of communication. And you know it will be months before life will return to normal. Sound familiar? This is what many of us are experiencing during these times of COVID-19 lockdown – but it also describes the life of an astronaut aboard the International Space Station.
There are, however, real physical risks to being in space. Earlier this year, an unnamed astronaut developed a blood clot in space for the first time – a common health problem which affects at least one person in 1000 on Earth. Now our new study, published in Aerospace Medicine and Human Performance, reveals what the risks of this happening again in space are – and how we can ultimately minimise them.
On Earth, blood clots commonly affect the lungs (pulmonary embolism) causing difficulty in breathing, or the legs (deep vein thrombosis), causing pain and swelling in the affected leg. The blood clot that occurred in space, however, was unusually positioned in the neck. Doctors on Earth applied an innovative treatment for the the astronaut in space by prescribing a mixture of injectable and oral medication – preventing a potentially mission-critical or even life-threatening event from progressing further.
Blood clots are life-threatening, as they can cause heart attacks or strokes and lead to huge health related costs on Earth. However, they are preventable and can be treated. We already know that factors such as obesity, a sedentary lifestyle, advancing age and smoking increase the risk.
The recent incident in space highlighted the need to find out whether astronauts really are at increased risk of blood clots in space, and what we can do to tackle them. If we want to send humans on long journeys to Mars and beyond it is crucial that we have this information.
It is especially pressing for female astronauts. Many use the combined hormonal contraceptive pill to control their menstrual cycles in space – a known risk factor for developing blood clots. When taken continually the pill can stop women from having periods in space, which is difficult given that washing water is limited and changing sanitary products while floating in space is challenging.
Our study examined the known risk factors for developing a blood clot, within a group of 38 female astronauts who travelled to space from 2000-2014, to understand if spaceflight causes any changes to the risk of developing a blood clot. This is the largest cohort study of female astronauts ever to have been conducted.
It showed that, on average, female astronauts were 44.6 years old during a long mission, an age at which the combined hormonal contraceptive pill would not usually be prescribed here on Earth because of the risk of developing a blood clot. The data showed that, after a spaceflight mission, the astronauts were not more likely to develop a blood clot than the average population.
The study also examined the change in blood markers from before and after spaceflight and found that the risk of developing a blood clot does not seem to increase by undertaking a spaceflight mission. This is reassuring, but it is important to keep in mind that the sample was still rather small.
What’s more, the astronauts may be protected because of the exercise they do, which reduces the risk. Their diet is also controlled, so they are receiving the optimal nutrients for their body and they are not dehydrated during their mission.
Lowering risk
That said, we have now seen that astronauts nevertheless can develop blood clots in space. Because of the huge risks of experiencing this in space, it is important that we lower the chances of it happening as much as possible. We recommend doing some extra blood tests prior to a spaceflight mission to help to evaluate an individual astronaut’s blood clot risk during astronaut selection and medical reviews.
Male and female astronauts all have the same intense pre-mission training schedules to ensure they are at the lowest risk of encountering health problems while they are in space. But activities during pre-mission training – for example long-haul travel or diving exercises to simulate the space environment – may transiently increase the risk of a blood clot developing. We therefore recommend that the timings of these events should be reviewed so that they do not occur in close succession, therefore inadvertently increasing the overall risk of developing a blood clot.
To further lower the risk, female astronauts could avoid using the combined hormonal contraceptive pill, which contains the hormones oestrogen and progestin. They could instead control their menstrual cycles by using progestin-only agents, which would further lower the risk of developing a blood clot.
NASA astronaut Cady Coleman, Expedition 26 flight engineer. NASA
Oestrogen does have bone-protecting properties though. That’s important, as astronauts are known to lose bone density when they travel to space. So there could alternatively be scope for using a combination of progestin-only agents with added oestrogen during spaceflight – albeit with safer and lower doses of oestrogen.
The study also provides lessons for living in lockdown back on Earth. Those of us transitioning to working from home have a more sedentary lifestyle than normal. There are reports of many people consuming more food in a bid to ease the anxieties of lockdown. Now, more than ever, we are reminded that physical activity of at least 30 minutes per day are vital in reducing our own blood clot risk – with simple measures like walking around your home being efficient.
About The Author:
Varsha Jain is a Visiting Researcher at the Centre of Human and Aerospace Physiological Sciences at King's College London
This article is republished from The Conversation under a Creative Commons license.
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I know I'm going to get yelled at, but the aforementioned friend didn't get HIV just because he couldn't afford PreP. Having sex without condom is how most people get HIV. And yes I do know that condoms are not perfect. IVD use is the other main culprit. Infection through blood transfusions are rarer every day.
All these people should have taken PreP? I wouldn't.
PreP works (mostly), but with many caveats. It's not like a pill you take after sex once like it is with anti-pregnancy medication.
PreP should be taken rigorously. To the point of taking it every day at the same time to the our. And depending on the drugs that are given as PreP twice a day. And the day you stop taking it, you can get infected almost immediatelly. You practically have to live like you are already infected. Not to mention these drugs cause liver damage.
And I don't even want to go into the viral drug resistances and the sudden increase of other STDs among people taking PreP. Like neurosiphillys. Or HPV and HepB. Or genital herpes. All because they thought they're taking PreP, they dont need other protection.
My original job, before COVID was HIV and viral Hepatitis molecular diagnostics. It still is, COVID just overwrites everything. I do mostly viral load testing, drug resistance testing, genotyping daily. So I'm quite familiar with the PreP debate, and I see the many side effects of these drugs.
The CDC didn't invent PreP. It's silly. It's invented by the drug companies. To sell their drugs to more people. The CDC merely allowed it's distribution. And Gilead is not the only drug company who makes drugs that can be used as PreP. Janssen, Merck (MSD), ViiV and many others are making drugs that can be used as PreP. They are just as bad as Gilead though when it comes to price gouging.
And I don't want to disappoint anybody but remdesivir is not a miracle cure either.
Tl:dr: Results: From 158 references, 15 studies were included in the review. The results showed that remdesivir has some potential benefits for hospitalized COVID-19 patients, as seen from clinical improvements such as faster recovery time, less duration of hospitalization, and fewer respiratory side effects among COVID-19 patients. However, the impact of remdesivir in reducing mortality remains uncertain.
Clinicians are giving it to people because we doesn't have anything better.
I really am sorry to be this disheartening. We really do have good drugs for HIV, even though they cost an arm and a leg. And there are studies for better ways of prevention than PreP.
One thing I wholeheartedly agree with OP, and that is the anger over how unimaginably soulless and greedy drug companies are though.
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“Paxlovid is usually very well-tolerated,” he says.īut people should stop taking Paxlovid and call a health care provider right away if they experience any of the following signs of an allergic reaction: Most people who take Paxlovid should not experience serious side effects, explains Dr. It’s important to note that although health care providers can write a prescription, pharmacists may also provide Paxlovid (with certain limitations) if they’ve opted to do so, provided you can share your electronic or printed medical records, including a list of medications you are already taking, and blood test results from the last 12 months. If you could become pregnant, it’s recommended that you use effective barrier contraception or do not have sexual activity while taking Paxlovid. If you are pregnant or breastfeeding, the FDA recommends discussing your options and specific situation with your health care provider, since there is no experience using the drug in these populations. The FDA granted the EUA in December, just as a staggering number of people were infected with Omicron and the need for care skyrocketed, leading to supply issues. The hope is that the restrictions on who can take Paxlovid will be relaxed over time. The more underlying medical conditions a person has, the higher their risk for developing a severe case of COVID-19, according to the CDC. That means you must either have certain underlying conditions (including cancer, diabetes, obesity, or others) or be 65 or older (more than 81% of COVID-19 deaths occur in in this group). But in order to qualify for a prescription, you must also have had a positive COVID-19 test result and be at high risk for developing severe COVID-19. The FDA authorized Paxlovid for people ages 12 and older who weigh at least 88 pounds. We asked Yale Medicine infectious diseases experts common questions about Paxlovid. The FDA also granted an EUA in December to a pill from Merck called molnupiravir (Lagevrio), but some studies suggest that molnupiravir has only a 30% reduction in the risk for hospitalization and death from COVID-19.Īnd as far as convenience, this medication is considered an improvement over treatments like remdesivir (approved by the FDA in October 2020), which is administered by intravenous (IV) injection. It’s important to note that Paxlovid (the brand name for the drug, which is made up of two generic medications-nirmatrelvir and ritonavir) isn’t the only pill available to treat COVID-19. It shows clear benefit, and it really can prevent hospitalization and death in people who are at high risk.” “It's really our first efficacious oral antiviral pill for this virus. “I think it is the beginning of a ‘game-changer,’” says Scott Roberts, MD, a Yale Medicine infectious diseases specialist. government while there is a public health emergency) and, perhaps most reassuring, it is expected to work against the Omicron variant.
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The drug, developed by Pfizer, has a lot of positives: It had an 89% reduction in the risk of hospitalization and death in the clinical trial that supported the EUA, a number that was high enough to prompt the National Institutes of Health (NIH) to prioritize it over other COVID-19 treatments and it’s cheaper than many other COVID-19 drugs (it’s provided for free by the U.S. So, if you test positive for the coronavirus and you are eligible to take the pills, you can take them at home and lower your risk of going to the hospital. Paxlovid is an oral antiviral pill that can be taken at home to help keep high-risk patients from getting so sick that they need to be hospitalized. The drug was granted an emergency use authorization (EUA) by the Food and Drug Administration (FDA) in December for anyone ages 12 and older who weighs at least 88 pounds, and is at high risk for severe disease. Paxlovid is the latest COVID-19 treatment that’s been all over the news. Because information about COVID-19 changes rapidly, we encourage you to visit the websites of the Centers for Disease Control & Prevention (CDC), World Health Organization (WHO), and your state and local government for the latest information. Note: Information in this article was accurate at the time of original publication.
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Steel Bite Pro Reviews (USA,UK,CANADA,AUSTRALIA,NEW ZEALAND):What They Don't Tell You ?
Steel Bite Pro can be used as a low cost supplement to reduce the costs of expensive dental treatment. This includes removal of tooth decay, gum infection, gum swelling, bleeding, and the prevention of tooth loss.
Periodontal disease or deteriorating gingals is the root cause for tooth decay and falls. About 20% of Americans suffer from this condition. Decaying gums affects almost everyone over 50. What if we told people that bad oral hygiene had nothing to do w/ gum disease, tooth loss, and halitosis. Poor hygiene is not the main cause of bad breath or teeth falling out. Dental problems can be caused by harmful bacteria living in the gums. This bacteria erodes the roots of the teeth and spreads COVID to nose, throat and lungs.
These germs can't be eliminated by even the most thorough of mouth washing.
Even if you don't have any obvious problems, your mouth is full of these bad guys.
You can finally eliminate bleeding gums as well as dental cavities, plaque, and bad smell with a simple hack that's easy to implement at home and costs less than 60 seconds. There is no better way to avoid unpleasant and costly dental treatment than by using this simple hack at home.
Steel Bite Pro delivers high-performance, dental support. It protects teeth's whiteness, helps to keep gums healthy, reduces the risk of periodontitis and gum disease, and stops teeth becoming loose or falling out. It is the most natural way to save your teeth and gums.
Steel Bite Pro is also effective in preventing gum bleeding and receding. The dental supplement targets termite microbes that live deep under the gums. This is where toothbrushes, floss, and mouthwashes cannot reach. This function is accomplished by strengthening the saliva in your mouth.
This product was designed by professionals to help one have stronger teeth, better breath, independence from gum disease, and a healthier mouth.
Steel Bite Pro helps you eliminate the bacteria and plaque that can lead teeth to decay. Thomas Spear, creator of Steel bite Pro, says that the formula doesn’t need to be approved for use by dentists. However, it can help reduce visits to the professionals and provide an all natural solution to combat predatory bacteria.
Steel Bite Pro, thanks to Doctor S. T. and Thomas Spear, has quickly become a highly-respected natural dental supplement that helps boost oral hygiene from inside out. This supplement enhances saliva pH properties to protect against tartar plaque and other harmful substances that can lead to tooth decay and gum disease.
It's not hard to believe how bad dental problems can become as we age. According to data from the CDC (Department of Adult Oral Health), nearly half of all adults age 30 or older have signs of gingivitis. Gingivitis, periodontitis (broken teeth), and oral cancer are all problems that can affect your dental health. These issues can be very costly.
New scientific breakthroughs are now available to solve dental problems. Steel Bite Pro, this is the name of the solution. This review will show you what this formula is about, how it works, the ingredients and how to get it. You should also review the Steel Bite Pro scam complaints. After going through negative reviews and side effect reports, you will need to know what they are. This article also contains a brief overview of the Steel Bite Pro Better Business Bureau. It is intended to assist consumers looking to make an informed decision about where and how to buy real Steel Bite Pro Supplement pills.
Let's examine Steel Bite Pro formula closely and determine if it's truly revolutionary. It's based upon premium-grade oils, plants, herbs, and herbs. It transforms saliva into the most potent disinfectant, rejuvenating your entire mouth for optimal oral hygiene.
OFFICIAL WEBSITE- www. steelbitepro24. com
What is Steel Bite Pro exactly?
Steel Bite Pro dietary supplement is organic and designed to support oral hygiene. According to the manufacturer, it can help reduce the risk of developing any dental diseases. Steel Bite Pro can be found on their official website. It is made up of 23 natural ingredients that will benefit your teeth, gums, and entire mouth.
The supplement contains 29 amazing superfoods which help to reduce pain and treat all dental problems. According to the manufacturer of the supplement, over 57,000 people have used it since its launch. In just a few short days, all previous users reported achieving optimum results.
The FDA approved facility in which the product is made is important. Each pill was made according to the strictest standards. This ensures that the product remains 100% safe. It is also free of side effects. It doesn't contain harmful chemicals or additives.
Steel Bite Pro also covers oral hygiene. It works by cleaning the entire mouth and eliminating harmful bacteria, plaque, germs, and other harmful elements. You shouldn't expect the supplement will work without you doing your part.
The full potential to the Steel Bite Pro supplement will only be possible if you also take good care of your teeth. Continue to brush your teeth daily at least twice and floss every other day after meals. This will help the supplement reach its intended goals.
It is a low cost supplement that will help save money, pain, and time on expensive dental treatments for tooth decay and gum infection, bleeding, swelling, and falling teeth.
People can reduce their risk of getting gum and gum infections, periodontal disease, gingivitis, and gum and gum diseases by doing this. These can cause gum swelling and gum receding, as well as teeth falling out and loosening. These can be avoided, which can result in costly and unpleasant dental operations such as root canals.
Steel Bite Pro also strengthens, whitens, and repairs nail enamel chips.
It eventually eradicates termite-bacterium from deep within the teeth.
It can also be used to clean out the mouth of microorganisms. It can also help to prevent tooth decay and plaque buildup.
OFFICIAL WEBSITE- www. steelbitepro24. com
Steel Bite Pro Where Can I Buy It?
Many consumers want to be able to see the total cost of Steel Bite Pro's supplement before reading this comprehensive review. Below you will find all the details about the price and formula of Steel Bite Pro, as well the policy regarding refunds. These packages include:
* One bottle is $69
* Three bottles for $177 ($59 Each)
* Six bottles for $294 ($49 ea)
You don't need to pay shipping charges for any of the options. All orders come with a 60-day returns policy. Steel Bite Pro is now the ideal time to learn more about it and find out why this natural formula for oral hygiene is rapidly becoming the most highly recommended.
Steel Bite Pro Ingredients
The dental supplement includes more than 29 components, all sourced from the finest regions of the world. To ensure their purity and effectiveness, all herbs, mineral, and extracts are tested in rigorous laboratories. These ingredients are combined to make the most potent combination.
Here are some key ingredients.
Berberine, a powerful anti-inflammatory and antioxidant plant, is now available. More than 79 clinical tests have proven its effectiveness against dangerous microorganisms including viruses, bacteria, and mold.
Berberine has been shown to be effective in removing other microorganisms like bacteria and parasites.
Turmeric has been a well-known and widely used antibacterial herb and spice. It has been shown in studies to reduce plaque, hidden bacteria, and irritation of gums.
Milkthistle has been shown in studies to heal liver damage from heavy metals, such as mercury, lead arsenic and cadmium. These heavy metals can build up in your liver and cause permanent damage.
Artichoke, Chanca Piedra, and Red Raspberry contain high amounts of vitamins and mineral such as vitamin B, C, K, and phosphorus. These minerals are helpful in treating infections of the mouth.
Artichoke is loved for its many nutrients which can help to reduce the cholesterol that clogs your arteries. It is good for the liver, digestive system, as well as fiber.
Red raspberry is rich with antioxidants which protect against heart disease, cancer, and other diseases like quercetin and vitamin C. Antioxidants are linked to inflammation relief. They could also be preventative against certain types of cancer. Steel Bite Pro is a great supplement to red raspberries.
Chanca piedra is most commonly used in supplements to protect the liver, kidneys, stomach, and rest of the digestive tract from diseases. It also reduces inflammation by eliminating bacteria and viruses. Some people use it to treat their diuresis.
Yarrow It cements the gums to prevent germs growing in tiny spaces. Yarrow can increase the number of fibroblasts (cells responsible for the regeneration of connective tissues). Yarrow can also help with the healing of injuries.
Beetroot is also helpful in healing dental lesions. Because of its ability to transform beetroot into Nitric oxide in the human body, it prevents tooth decay. This increases the effectiveness of the saliva in fighting germs, and reduces the risk of developing harmful bacteria in the plaque.
Jujube and Jujube plants, Zinc - These nutrients and minerals are essential for tooth crowns. Alfalfa provides iron, calcium, magnesium and potassium while Dandelion Greens offer iron, calcium, magnesia, and potassium.
Jujube seeds are rich in Vitamin C which is an antioxidant and immune stimulant.
Zinc is a trace metal that is naturally found within saliva. It prevents the formation plaque and germs.
Combination of yellow dock, chicory root (with celery seed), and burdock root (with chicory root), this powerful combination aids in clearing and detoxifying the intestines. They also help to reduce inflammation and increase mineral absorption.
Grape Extract: This hinders the development of common foodborne bacteria in the mouth.
Ginger contains gingerol which is an active component that prevents germs from spreading and helps to avoid illness.
Feverfew is an herbal pain relief that has no side effects.
L-Cysteine (detox) and Methionine (for detoxification) are two amino acids.
OFFICIAL WEBSITE- www. steelbitepro24. com
How do you use Steel Bite Pro?
The capsules are easy to swallow. You only need to take 2 capsules of the supplement with water each day.
It is important to check with your doctor before you start taking the supplement. It is possible to expect results within a few working days.
Is Steel Bite Pro safe to be used?
Each tablet of this innovative solution to dental problems is manufactured in the United States, in an FDA-approved laboratory. GMP certified is the facility.
The product is produced under strict regulations in a safe environment. Steel Bite Pro therefore is completely safe.
This supplement does not contain any GMOs and is free from harmful toxins. It doesn't become a habit.
Steel Bite Pro Pills - Key Features
Steel Bite Pro is featured in LA Weekly.
* Made with natural ingredients
* Produced within an FDA-approved facility
* It's non GMO and made in USA
To last for a longer time, each bottle contains 60 capsules
* A 60-day money back guarantee
It helps with bleeding and gum disease.
Gums improve your health.
It helps to relieve pain and prevents the development of tooth infections.
The cost of a painful root canal or other dental procedure can be saved by thousands of dollars.
It helps to eliminate plaque buildup.
Whiten discolored and stained teeth
Gums should be tightened.
Gingivitis or periodontal problems are eliminated.
It eliminates bad breath.
It makes you smile with a beautiful, healthy smile.
It restores confidence by removing tartar and cavities from your teeth.
Not all dental implants are expensive and can cause nerve damage.
It will be a distant memory that people never again have to visit the dentist.
Never again spend money on medication or dental bills.
Steel Bite Pro's unique method allows for stronger saliva to combat oral infections and gum diseases.
It is safe to use regardless of age and medical condition.
Steel Bite Pro is helping over 57,000 Americans to improve their dental health.
It freshens your breath.
It can eliminate cavities and caries.
It removes tartar and plaque.
It can be used to reduce yellowing of teeth.
It cleanses and detoxifies liver.
It is a natural protective barrier for the teeth and gums.
It is rich in potent antioxidants.
It is also a great way to help you achieve your oral health goals.
Returns and Refund Policy
Buyers have a 60-day no-questions-asked guarantee of 100% money-back.
OFFICIAL WEBSITE- www. steelbitepro24. com
FAQ
Is Steel Bite Pro bad for your health?
Yes, it is an effective and natural oral health product. Steel Bite Pro can be used by 57000 people from all over the planet. Each of the dental supplements pills are made in the United States, in a stateof-the art GMP facility FDA approved.
How long does it take for the results of your tests to be apparent?
Within 3-4 business days, initial results will be made available. For a meaningful effect to last, however, users need to take the supplement at least for three months or 90 consecutive days.
Where can one purchase Steel Bite Pro?
It is recommended that only the original website www .steelbitepro24 .com be used to purchase any dental supplements.
Who Is the Steel BitePro Manufacturer?
Steel Bite PRO is not available for purchase. Thomas Spear, who is the creator and inventor of Steel Bite, is all that is known. There's a catch. Thomas Spear is only a pen name. It's not reliable data, therefore. These facts prove that Steel Bite Pro does not have the credibility to be a reliable supplement. Fortunately, its ingredients are the saving grace. "Privacy concerns" won't cut the mustard when it comes to disclosing a manufacturer's name.
Steel Bite Pro: Where are they made?
Steel Bite Pro has been manufactured in the United States of America in an American Good Manufacturing Practice (GMP), certified facility. The location is unknown.
Where is Steel Bite Pro Distributed?
Steel Bite Pro distribution is from 37 Inverness Drive East Suite 130 Englewood Colorado USA
Are There Similar Studies Concerning Steel Bite Pro
Yes! Steel Bite Pro has been the subject of numerous related studies. We checked the references listed by Steel Bite Pro to determine if this supplement is scientifically valid.
Steel Bite Pro used data from the University of Michigan's School of Dentistry. The studies they obtained were also from non-scholarly sources. These aren’t necessarily verified. A closer look revealed that not all of the links are valid anymore. This makes it difficult to verify that the product is indeed genuine. So, there is a mixed view on the matter. Steel Bite Pro is plausible, but not credible at the same moment. This review will allow you to have doubts about Steel Bite Pro halfway through.
OFFICIAL WEBSITE- www. steelbitepro24. com
What Are the Benefits of Steel Bite PRO?
Steel Bite Pro benefits are numerous for people who want to solve their oral issues. Let's take a look at the physical advantages. Steel BitePro is a supplement designed to ease your pains and stop bleeding from your weak gums. The best thing about Steel Bite Pro is the freedom to live your life, without having to worry about what happens in your mouth. Toothache is a serious problem that can cause severe pain and affect your professional life. You can enjoy the comfort it brings.
The mental benefits of confidence increase with time. Poor oral hygiene, such as disoriented teeth alignment and bad breath, can result in unwelcome remarks from those around you. People can be more harsh in certain situations and less sympathetic to your suffering. This can lead depression and sadness. It's also possible to not control oral diseases which can make you very unhappy. The supplement will work for both your mental and physical health. You will feel normal, and it won't matter if you are embarrassed to be yourself.
What Are the Side Effects of Steel Bite PRO?
Steel Bite Pro doesn't have side effects. Steel Bite PRO contains only natural ingredients. Side effects won't be an issue as long you adhere to the recommended dosage. Steel Bite Pro is recommended to take two (2) capsules daily. You can always go lower but not higher.
Side effects may occur if you take more than recommended dose, which is three (3) capsules a day. Stop taking this product as soon as you notice any side effects. Consult your doctor immediately.
Steel Bite Pro Where to Buy?
Steel Bite Pro can be purchased only through their website www. steelbitepro24 .com. This will allow you to enjoy certain discounts and money back guarantees. Additionally, you have a trusted shipping partner.
Conclusion: Steel Bite Pro
We now know that the causes of bad breath, tooth decay and gum disease are not related to how effective your dental hygiene routine is. However, termite like bacteria lurking deep under the gums can eat at the roots, loosen them and cause them to fall. These germs can spread quickly to the throat, nose, and sinuses.
It is not possible to reach these areas with expensive dental procedures, such as brushing your teeth or using mouthwashes.
Steel Bite Pro, which converts saliva to a powerful disinfectant or strengthener of teeth, is the only solution to this oral epidemic.
What does Steel Bite Pro cost?
Steel Bite Pro bottles cost $69 each. The usual price is $99 but the manufacturer should set the price at $69. Steel Bite Pro offers bulk orders if customers want more discounts.
For $59, you can buy the three-month supply bundle. It's $177 for the entire package, as opposed to $297 at the regular price!
You will also get the best Steel Bite Pro deal, the six month supply package. This package gives you a bottle for just $49! This package is only $294, which means six bottles are available for as low as $594.
In which countries is Steel Bite PRO available?
Steel Bite Pro only is available in the United States and Canada.
How Much Does Steel Bite pro Charge for Shipping?
Shipping costs vary from country to country. However, if you are a resident of the United States, there is no shipping charge.
Shipping costs in Australia start at $46.95
Canada's shipping fees are $15.95
In Ireland, shipping fees are $87.24.
New Zealand's shipping cost is $62.44.
Shipping costs in the United Kingdom start at $77.94
What are the payment options available when you buy Steel Bite pro?
Steel Bite Pro can either be paid with your Discover, American Express Visa, Diner's Club MasterCard, Visa credit card, PayPal account or via your Visa credit card.
Steel Bite pro offers a money-back guarantee
Yes! Steel Bite Pro provides a comprehensive 60-day guarantee. It will not let you feel conned by the product. According to their website, 100% of your money will be refunded if you don’t notice any improvement in the condition of your oral disease. Shipping fees are not included. They will refund the shipping costs. To be eligible for a refund, send the bottles to 37 Inverness Drive East. Steelbite Pro, Englewood. Colorado 80112.
OFFICIAL WEBSITE- www. steelbitepro24. com
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Benefits and Causes of Preventive Medicine
The profession of preventive medicine involves encouraging preventive healthcare to enhance patient wellbeing. The ultimate objective is to avert illness, incapacity, and death. Medical professionals, including those who specialize in preventive medicine, are licensed preventive medicine physicians.
Hand washing, breastfeeding, and vaccinations are a few basic examples of preventative medicine. Examinations and screening procedures that are specific to a person's age, health, and family history may be included in preventive care.
Primary prevention involves actions that all patients can take to prevent some diseases from developing, such as immunization, use of birth control and condoms, regular dental cleanings and treatment, and hand-washing. These are examples of preventive medicine kinds.
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Below are some examples of preventive medicine:
Immunization and its importance:
This is the procedure by which a person receives immunization protection against a disease. This phrase is frequently used synonymously with the words vaccination or inoculation.
Immunizations prevent death. It safeguards your neighborhood, your family, and yourself. Immunization prevents diseases from spreading, so protecting future generations. As a result of immunization programs, many infectious diseases are now uncommon or extinct, yet new infectious diseases are constantly emerging all over the world.
Numerous diseases that were once considerably more prevalent can now be prevented with vaccinations. Examples include polio, tetanus, diphtheria, measles, mumps, and pertussis. Numerous of these infections have the potential to result in catastrophic or fatal illnesses as well as lifelong health issues.
Immunization is the process of developing a disease immunity in response to a vaccination. When you receive a vaccine, you may do so orally or through a needle. Vaccines function by triggering a healthy immunological response in the body.
Uses of birth control
When used consistently each day, the birth control pill is a fairly efficient technique to prevent pregnancy. Additionally, the pill can reduce your risk of developing conditions like ovarian and uterine cancer, migraines, and acne. Some women suffer nausea as a side effect of medicine, however this is typically transient.
The most frequent adverse effects are headaches, nausea, aching breasts, and spotting or bleeding between periods. However, symptoms often disappear within two to three months and don't affect everyone who takes the medication. You shouldn't feel ill or unpleasant while using birth control.
Hand Washing
The greatest approach to avoid getting sick has always been to wash your hands frequently. The epidemics of the coronavirus (COVID-19), however, make hand washing more important than ever.
Coronaviruses are quickly transmitted. Coronavirus and other pathogens are stopped from spreading by frequent hand washing.
You defend yourself from germs when you wash your hands. Additionally, you defend members of your family. And in the case of the coronavirus, preventing the spread of germs at home also protects those in the neighborhood.
Community Health
As both areas concentrate on the detection, prevention, and education of health disparities, the distinctions between public health and conventional medicine can become hazy. Many public health practitioners also study medicine, and they discover that keeping up with medical developments also requires keeping up with public health developments.
The Centers for Disease Control and Prevention and other organizations that have a focus on public health publish a list of the year's top public health issues every year. To enable public health experts reach communities across the United States for better health, new and developing challenges must also be addressed even if many problems persist from year to year.
Preventative Healthcare
Prophylaxis, often known as preventive healthcare, refers to actions made to stave off disease. Disease and disability are dynamic processes that start before people are aware they are affected. They are influenced by environmental variables, genetic predisposition, disease agents, and lifestyle choices. Primal, primary, secondary, and tertiary preventive measures are the cornerstones of disease prevention. Millions of individuals die from avoidable causes each year. Approximately half of all deaths in the United States in 2000 were attributable to avoidable exposures and behaviors, according to a 2004 study. Cardiovascular disease, long-term respiratory conditions, accidental injuries, diabetes, and a few viral disorders were the main contributors. According to the same study, poor food and a sedentary lifestyle are believed to be the cause of 400,000 deaths annually in the United States. This is an increase from 2000, when these illnesses were responsible for 60% of deaths.
What Do Doctors in Preventive Medicine Do?
A doctor with skills in both clinical treatment and public health is known as a preventative medicine specialist. As a result, they can offer knowledge and experience about the prevention of illness, injury, and death.
Primary care offices, corporations, public health departments, healthcare facilities, and health insurance providers all practice preventive medicine. You've used preventative medicine if you've ever had a screening for diabetes or high blood pressure and had the disease treated before it manifested.
Preventive medicine doctors work to help individuals before a sickness or illness arises, in contrast to other doctors and specializations that concentrate on treating patients after they get ill. Prior to the necessity for treatment, their objective is to prevent health problems.
How can preventive medicine save lives, and why is it superior to treatment?
The Centers for Disease Control and Prevention estimate that every year in the United States, preventative care services might save over 100,000 lives. Seven out of ten deaths in the United States each year are caused by chronic diseases such as cancer, diabetes, and heart disease.
Rather than treating patients after they become ill, it is much preferable to avoid sickness. This is especially true for chronic illnesses, which are linked to misery, a high death rate, and expensive medical care.
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