#oligonucleotide manufacturing

[franchisesales]

Details Presentation Exactmer Ltd

Exactmer manufactures exact polymeric pharmaceuticals, enabling advanced therapies to be provided to all patients in need.Exactmer attains ISO9001 certification and launches development projects with new clients.Exactmer performs the first technology transfer of its Nanostar Synthesiser to a large pharmaceutical company.

Londoneast-uk Business and Technical Park,Yew Tree Avenue,Dagenham,RM10 7FN

sales@exactmer.com

+44 (0) 203 773 2216

https://exactmer.com/

[asymchem1]

Oligonucleotides Manufacturing | Asymchem

Asymchem specializes in the high-quality manufacturing of oligonucleotides. Discover our advanced solutions for oligonucleotide synthesis and pharmaceutical applications.

[surbhijamdade]

Revenue Forecast and Competitive Landscape for the Oligonucleotide Synthesis Market

The Oligonucleotide Synthesis Market Report for 2024 provides a comprehensive overview of the Oligonucleotide Synthesis Market industry, presenting crucial data and insights into market dynamics, including growth drivers, challenges, and future potential. The report evaluates the Oligonucleotide Synthesis Market Components, focusing on significant opportunities and trends that could shape the industry's trajectory.

According to Straits Research, the global Oligonucleotide Synthesis Market market size was valued at USD 7.74 billion in 2023. It is projected to reach from USD 8.84 billion in 2024 to USD 25.57 billion by 2032, growing at a CAGR of 14.2% during the forecast period (2024–2032).

Get a Sample PDF/Excel of report starting from USD 995 :https://straitsresearch.com/report/oligonucleotide-synthesis-market/request-sample

Top Key Players of Oligonucleotide Synthesis Market :

Agilent Technologies, Inc.

ATDBio Ltd.

TriLink BioTechnologies LLC

Thermo Fisher Scientific

Nitto Denko Corporation

Merck KGaA

LGC Biosearch Technologies

Integrated DNA Technologies, Inc.

GenScript

GE Healthcare

Eurogentec

Eurofins

and more....

Key Insights from the Oligonucleotide Synthesis Market Report

Market Size Overview: The report provides comprehensive estimates of the Oligonucleotide Synthesis Marketsize, including value and sales volume, for the period.

Market Trends and Dynamics: An analysis of the key drivers, opportunities, challenges, and risks shaping the Oligonucleotide Synthesis Market.

Global Economic and Regional Impact: Evaluation of the effects of global inflation and the Russia-Ukraine conflict on the Oligonucleotide Synthesis Market.

Trade Flow Analysis: Detailed examination of import and export volumes of Oligonucleotide Synthesis Marketacross major regions.

Industry Value Chain: Insight into the Oligonucleotide Synthesis Marketvalue chain, covering raw materials, suppliers, manufacturing processes, distributors, and downstream customers.

Industry News, Policies, and Regulations: Coverage of the latest developments, policies, and regulations impacting the Oligonucleotide Synthesis Market.

Regional Analysis for Oligonucleotide Synthesis Market:

The regional analysis section of the report offers a thorough examination of the global Oligonucleotide Synthesis Market market, detailing the sales growth of various regional and country-level markets. It includes precise volume analysis by country and market size analysis by region for both past and future periods. The report provides an in-depth evaluation of the growth trends and other factors impacting the Oligonucleotide Synthesis Market market in key countries, such as the United States, Canada, Mexico, Germany, France, the United Kingdom, Russia, Italy, China, Japan, Korea, India, Southeast Asia, Australia, Brazil, and Saudi Arabia. Moreover, it explores the progress of significant regional markets, including North America, Europe, Asia-Pacific, South America, and the Middle East & Africa.

Oligonucleotide Synthesis Market Segmentations:

By Product Type

Synthesized Oligonucleotide Product

Reagents

Equipment

By Applications

Research

PCR

Sequencing

Gene Synthesis

Diagnostics

Therapeutics

RNAi

Nucleic Acid Aptamers

Others

By End-User

Academic Research Institutes

Pharmaceutical and Biotechnology Companies

Diagnostic Laboratories

Others

Get Detail Market Segmentation :https://straitsresearch.com/report/oligonucleotide-synthesis-market/segmentation

Unit Economics must be known by C-suite professionals:

Cost of Goods Sold (COGS): Includes material, labor, and overhead costs in manufacturing.

R&D Costs: Investment in innovation and compliance with regulations.

Engineering and Design Costs: Resources for design, prototyping, and meeting technical standards.

Production Costs: Specialized manufacturing and quality control expenses.

Supply Chain Costs: Managing procurement and logistics for specialized components.

Testing and Quality Assurance: Costs for ensuring product safety and reliability.

SG&A Costs: Marketing, sales, and administrative expenses.

Revenue per Unit: Income from contracts, services, and licensing.

Gross Margin: Revenue minus COGS, showing unit profitability.

Break-even Analysis: Units or contracts needed to cover total costs.

Customer Acquisition Cost (CAC): Costs to secure new contracts.

Lifetime Value (LTV): Total revenue from a customer over time.

Capital Expenditure (CapEx): Investments in facilities and technology.

Economies of Scale: Cost reductions in larger production runs.

Profit Margin: Final profit after all expenses.

Top Reasons to Choose This Report

Access to Comprehensive Insights: Gain access to extensive analysis, research, and data that are often challenging to gather independently. This report provides valuable information, saving you significant time and effort.

Support for Informed Decisions: Enhance your decision-making process with in-depth insights into market trends, consumer behavior, and key industry factors. This report is essential for strategic planning, including investments, product development, and marketing strategies.

Gain a Competitive Edge: Stay competitive by understanding market dynamics and competitor strategies. The report provides detailed insights into competitor performance and market trends, helping you craft effective business strategies.

Cost-Effective Research Solution: Save on research costs by investing in this report, which offers a detailed and comprehensive analysis of the market. This cost-effective option eliminates the need for extensive independent research.

COVID-19 Aftermath and Geopolitical Influences: Russia-Ukraine Conflict and Middle East Crisis

The report explores the multifaceted impact of COVID-19 on the Oligonucleotide Synthesis Market market, covering both direct and indirect effects across global and local levels. It discusses market size, trends, and growth trajectories in the Oligonucleotide Synthesis Market , classified by type, application, and customer sector. Additionally, it provides a detailed evaluation of market development components before and after the pandemic, supported by a PESTEL analysis to assess key influencers and barriers to market entry. We offer the flexibility to customize the report based on specific regions, applications, or any other statistical details. Our goal is to align our analysis with your specific needs, ensuring a more complete market study. The final report will also examine the impact of the Russia-Ukraine War on the Oligonucleotide Synthesis Market market, assessing how these geopolitical events are influencing current market conditions and future opportunities.

This Report is available for purchase on :https://straitsresearch.com/buy-now/oligonucleotide-synthesis-market

About Us:

Straits Research is a leading research and intelligence organization, specializing in research, analytics, and advisory services along with providing business insights & research reports.

Contact Us: email: sales@straitsresearch.com Address: 825 3rd Avenue, New York, NY, USA, 10022 Tel: +1 646 905 0080 (U.S.) +91 8087085354 (India) +44 203 695 0070 (U.K.)

[jayanthitbrc]

Global Peptide And Oligonucleotide CDMO Market Analysis 2024: Size Forecast and Growth Prospects

The peptide and oligonucleotide cdmo global market report 2024from The Business Research Company provides comprehensive market statistics, including global market size, regional shares, competitor market share, detailed segments, trends, and opportunities. This report offers an in-depth analysis of current and future industry scenarios, delivering a complete perspective for thriving in the industrial automation software market.

Peptide And Oligonucleotide CDMO Market, 2024report by The Business Research Company offers comprehensive insights into the current state of the market and highlights future growth opportunities.

Market Size - The peptide and oligonucleotide CDMO market size has grown rapidly in recent years. It will grow from $1.93 billion in 2023 to $2.16 billion in 2024 at a compound annual growth rate (CAGR) of 11.8%. The growth in the historic period can be attributed to a rise in demand for therapeutic agents, advancements in synthesis and manufacturing, personalized medicine trends, regulatory guidelines, and increased focus on antiviral peptides and mRNA vaccines highlighting the potential of oligonucleotides in vaccine development.

The peptide and oligonucleotide CDMO market size is expected to see rapid growth in the next few years. It will grow to $3.39 billion in 2028 at a compound annual growth rate (CAGR) of 12.0%. The growth in the forecast period can be attributed to the growing demand for personalized medicine, advancements in biotechnology, expanding applications, increasing outsourcing, and the growing burden of chronic diseases. Major trends in the forecast period include personalized therapies, technological advancements, quality control challenges, global expansion, and increased collaboration among biopharmaceutical companies.

Order your report now for swift delivery @ https://www.thebusinessresearchcompany.com/report/peptide-and-oligonucleotide-cdmo-global-market-report

Scope Of Peptide And Oligonucleotide CDMO MarketThe Business Research Company's reports encompass a wide range of information, including:

1. Market Size (Historic and Forecast): Analysis of the market's historical performance and projections for future growth.

2. Drivers: Examination of the key factors propelling market growth.

3. Trends: Identification of emerging trends and patterns shaping the market landscape.

4. Key Segments: Breakdown of the market into its primary segments and their respective performance.

5. Focus Regions and Geographies: Insight into the most critical regions and geographical areas influencing the market.

6. Macro Economic Factors: Assessment of broader economic elements impacting the market.

Peptide And Oligonucleotide CDMO Market Overview

Market Drivers -The growing adoption of personalized medicine is expected to propel the growth of the peptide and oligonucleotide CDMO markets going forward. Personalized medicine is an approach to healthcare that tailors medical decisions and treatments to individual characteristics, such as genetics, environment, and lifestyle. The growing adoption of personalized medicine is due to several factors such as advancements in genomic technologies, increased understanding of disease mechanisms at the molecular level, and the demand for more effective and targeted treatment options tailored to individual patients' genetic profiles and medical histories. Peptide and oligonucleotide contract development and manufacturing organizations (CDMOs) play a crucial role in personalized medicine by producing customized therapeutic peptides and oligonucleotides tailored to individual patient needs. For instance, in February 2024, according to the Personalized Medicine Coalition, a UK-based organization promoting the adoption of personalized medicine, the Food and Drug Administration’s (FDA) Center for Drug Evaluation and Research (CDER) approved 16 new personalized treatments for rare disease patients, up from 6 in 2022. Therefore, the growing adoption of personalized medicine is driving the growth of the peptide and oligonucleotide CDMO market.

Market Trends - Major companies operating in the peptide and oligonucleotide CDMO market are focusing on developing strategic partnerships to enhance their service offerings, expand their technological capabilities, and increase their market reach. Peptide development and production partnerships refer to collaborative agreements between two organizations focused on developing and manufacturing peptide-based therapeutics. For instance, in May 2023, PolyPeptide Group AG, a US-based contract development and manufacturing organization (CDMO), partnered with Numaferm GmbH, a Germany-based biotechnology company, for peptide development and production. This partnership aims to utilize PolyPeptide's cGMP manufacturing capacities and market access, along with Numaferm's expertise in sustainable peptide manufacturing and biochemical production platforms. The partnership is focused on jointly exploring the development of suitable peptide candidates with the goal of more sustainable production of peptide-based APIs.

The peptide and oligonucleotide cdmo market covered in this report is segmented –

1) By Product: Peptides, Oligonucleotides 2) By Service Type: Contract Development, Contract Manufacturing, 3) By Application: Therapeutics, Research Applications, Diagnostics, Other Applications 4) By End User: Biopharmaceutical Companies, Pharmaceutical Companies, Research Institutes, Academic and Government Organizations, Others End Users

Get an inside scoop of the peptide and oligonucleotide cdmo market, Request now for Sample Report @ https://www.thebusinessresearchcompany.com/sample.aspx?id=15892&type=smp

Regional Insights - North America was the largest region in the peptide and oligonucleotide CDMO market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the peptide and oligonucleotide cdmo market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East and Africa.

Key Companies - Major companies operating in the peptide and oligonucleotide cdmo market are Thermo Fisher Scientific Inc., Merck KGaA, Ajinomoto Co. Inc., Lonza Group Ag, Wuxi Apptec Co. Ltd., Catalent Inc., Piramal Pharma Ltd, Curia Global Inc., Almac Group, Euroapi SA., CordenPharma International, Bachem Holding AG, Genscript Biotech Corporation, PolyPeptide Group, Rentschler Biopharma SE, Ambiopharm Inc, ScinoPharm, Senn Chemicals AG, Aurigene Pharmaceutical Services, Creative Peptides, Sylentis S.A.

Table of Contents 1. Executive Summary 2. Peptide And Oligonucleotide CDMO Market Report Structure 3. Peptide And Oligonucleotide CDMO Market Trends And Strategies 4. Peptide And Oligonucleotide CDMO Market – Macro Economic Scenario 5. Peptide And Oligonucleotide CDMO Market Size And Growth ….. 27. Peptide And Oligonucleotide CDMO Market Competitor Landscape And Company Profiles 28. Key Mergers And Acquisitions 29. Future Outlook and Potential Analysis 30. Appendix

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[deshpandeisha]

Introduction to Reverse Phase Chromatography Resins: Principles and Applications

The global Reverse Phase Chromatography (RPC) resins market size is expected to reach USD 491.7 Million in 2032 and register a steady revenue CAGR of 7.12% during the forecast period, according to latest analysis by Emergen Research. The global reverse phase chromatography resins market is driven by several factors. Firstly, the increasing demand for pharmaceutical and biotechnology products is fueling the need for efficient purification techniques, thereby boosting the demand for reverse phase chromatography resins. Additionally, the growing focus on research and development activities in the healthcare sector is driving the market growth.

Furthermore, the rising prevalence of chronic diseases and the need for effective drug development are also contributing to the market expansion. Reverse phase chromatography resins play a crucial role in the purification of therapeutic proteins, antibodies, and other biomolecules, which are essential for the development of novel drugs.

However, there are certain restraints that may hinder the growth of the reverse phase chromatography resins market. One of the major challenges is the high cost associated with these resins. The production and purification processes involved in manufacturing reverse phase chromatography resins can be expensive, which may limit their adoption, especially in developing regions.

In terms of recent product launches, here are a few examples:

On 06 January 2021, Samsung launched large capacity Variable Refrigerant Flow (VRF) air conditioning systems in India that can be installed in just 0.5 square meters of space in premium apartments, villas, bungalows, houses as well as commercial and retail establishments.

On 15 March 2021, Thermo Fisher Scientific introduced the POROS™ Oligo (dT)25 Affinity Resin, a reverse phase chromatography resin designed for the purification of mRNA and other oligonucleotides. This resin offers high binding capacity and purity, enabling efficient mRNA purification for various applications.

On 22 May 2021, GE Healthcare launched the MabSelect PrismA™ chromatography resin, a next-generation protein A affinity resin for the purification of monoclonal antibodies. This resin offers improved binding capacity and productivity, allowing for faster and more efficient antibody purification processes.

The Global Reverse Phase Chromatography Resins Market report published by Emergen Research is a concise summary on the Reverse Phase Chromatography Resins industry and offers deep insights into the industry’s core structure and mechanism. The report digs into the key segments and sub-segments of the industry and offers a thorough study of the industry’s leading regional markets, competitive scenario, product and application segments, technology landscape, sales & distribution networks, and key industry statistics. Market insights included in the report have been compiled through extensive research, detailed market surveys, and expert interviews.

Claim Your FREE Sample Copy with Table of content@ https://www.emergenresearch.com/request-sample/1964

The leading market contenders listed in the report are: Cytiva, MERCK KGAA., Tosoh Corporation, Thermo Fisher Scientific Inc., Avantor, Inc., Purolite, Mitsubishi Chemical Corporation, Waters Corporation, Agilent Technologies Inc., and Sepax Technologies, Inc

The research study examines historic data from 2018 and 2020 to draw forecasts until 2030. The timeline makes the report an invaluable resource for readers, investors, and stakeholders looking for key insights in readily accessible documents with the information presented in the form of tables, charts, and graphs. To Visit Full Report & Table of Contents Reverse Phase Chromatography Resins Market: https://www.emergenresearch.com/industry-report/reverse-phase-chromatography-resins-market

Market Overview: The report bifurcates the Reverse Phase Chromatography Resins market on the basis of different product types, applications, end-user industries, and key regions of the world where the market has already established its presence. The report accurately offers insights into the supply-demand ratio and production and consumption volume of each segment. Segments Covered in this report are:

Resin Type Outlook (Revenue, USD Million; 2019–2032)

Silica-based resins

Polymer based resins

Particle Size Outlook (Revenue, USD Million; 2019–2032)

1-10 µM

10-50 µM

50-100 µM OR HIGHER

Flow Rate Outlook (Revenue, USD Million; 2019–2032)

40 ML/H - 90 ML/H

90 ML/H - 150 ML/H

150 ML/H Above

The research report offers a comprehensive regional analysis of the market with regards to production and consumption patterns, import/export, market size and share in terms of volume and value, supply and demand dynamics, and presence of prominent players in each market. Get An Impressive Discount On This Report@ https://www.emergenresearch.com/request-discount/1964

Regional Analysis Covers: North America (U.S., Canada) Europe (U.K., Italy, Germany, France, Rest of EU) Asia Pacific (India, Japan, China, South Korea, Australia, Rest of APAC) Latin America (Chile, Brazil, Argentina, Rest of Latin America) Middle East & Africa (Saudi Arabia, U.A.E., South Africa, Rest of MEA)

Key reasons to buy the Global Reverse Phase Chromatography Resins Market report:

The latest report comprehensively studies the global Reverse Phase Chromatography Resins market size and provides useful inference on numerous aspects of the market, such as the current business trends, market share, product offerings, and product share.

The report offers an insightful analysis of the regional outlook of the market.

It offers a detailed account of the end-use applications of the products & services offered by this industry.

The report holistically covers the latest developments taking place in this industry. Therefore, it lists the most effective business strategies implemented by the market rivals for ideal business expansion.

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Emergen Research is a market research and consulting company that provides syndicated research reports, customized research reports, and consulting services. Our solutions purely focus on your purpose to locate, target, and analyse consumer behavior shifts across demographics, across industries, and help clients make smarter business decisions. We offer market intelligence studies ensuring relevant and fact-based research across multiple industries, including Healthcare, Touch Points, Chemicals, Types, and Energy. We consistently update our research offerings to ensure our clients are aware of the latest trends existent in the market. Emergen Research has a strong base of experienced analysts from varied areas of expertise. Our industry experience and ability to develop a concrete solution to any research problems provides our clients with the ability to secure an edge over their respective competitors.

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[mordormr]

The Rising Promise of the Gene Therapy Industry

Gene therapy is revolutionizing modern medicine by offering the potential to treat or even cure genetic disorders by addressing the root cause of the disease. By altering or replacing defective genes, gene therapy is opening new doors for the treatment of conditions once thought incurable, such as certain cancers, genetic disorders, and neurodegenerative diseases. The gene therapy market size is projected to be valued at USD 7.18 billion in 2024 and is anticipated to grow to USD 24.67 billion by 2029, with a compound annual growth rate (CAGR) of 28% over the forecast period (2024-2029).

Key Market Drivers

Growing Prevalence of Genetic Disorders: With the rise in genetic diseases such as cystic fibrosis, hemophilia, and muscular dystrophy, the need for effective treatments is more critical than ever. Gene therapy offers a targeted approach, addressing the underlying cause of these conditions rather than just managing symptoms.

Technological Advancements in Biotechnology: The development of advanced technologies such as CRISPR-Cas9, viral vectors, and improved delivery mechanisms is propelling the gene therapy market forward. These innovations enhance the precision and efficiency of gene editing, making treatments more effective and accessible.

Increased Research and Development Investment: Pharmaceutical companies, governments, and academic institutions are heavily investing in gene therapy research. These efforts are accelerating clinical trials and regulatory approvals, driving the market's expansion.

Rising Approvals of Gene Therapy Products: Regulatory bodies like the FDA and EMA are increasingly approving gene therapy treatments, particularly for rare diseases. This growing number of approvals is boosting market confidence and attracting further investment.

Market Segmentation

The gene therapy market can be segmented by therapy type, application, vector type, and region:

By Therapy Type: Somatic gene therapy, germline gene therapy.

By Application: Oncology, rare diseases, cardiovascular diseases, neurological disorders.

By Vector Type: Viral vectors (adenovirus, lentivirus, retrovirus), non-viral vectors (naked DNA, oligonucleotides).

By Region: North America, Europe, Asia-Pacific, and Rest of the World.

Challenges Facing the Gene Therapy Market

Despite its immense potential, the gene therapy industry faces several challenges:

High Treatment Costs: Gene therapies are often expensive, with some treatments costing upwards of a million dollars per patient. While they offer life-changing results, the high cost can limit accessibility, particularly in developing regions.

Manufacturing Complexity: Producing gene therapies is complex and requires specialized facilities, technologies, and expertise. This complexity often leads to supply chain challenges and can hinder the scalability of treatments.

Ethical Concerns: Gene therapy, particularly germline editing, raises ethical questions about potential misuse or unintended consequences. Addressing these concerns is crucial for broader public acceptance and regulatory approval.

Long-Term Efficacy and Safety: As a relatively new field, the long-term efficacy and safety of gene therapies are still being studied. Some treatments may carry the risk of unintended genetic changes, which needs careful monitoring over time.

Regional Insights

North America: North America dominates the gene therapy market, driven by advanced healthcare infrastructure, significant R&D investment, and favorable regulatory support. The U.S. is home to several leading gene therapy companies and research institutions.

Europe: Europe is also a key player in the gene therapy market, particularly in the UK, Germany, and France. The region benefits from government support for rare disease research and a growing number of gene therapy clinical trials.

Asia-Pacific: The Asia-Pacific region is expected to experience rapid growth, with increasing healthcare investments, rising prevalence of genetic diseases, and expanding biotechnology research in countries like China, Japan, and India.

Future Outlook

The future of gene therapy is highly promising. With continued advancements in gene editing technologies and delivery mechanisms, the market is expected to grow at an impressive rate. More gene therapy products are anticipated to receive regulatory approvals in the coming years, and the ongoing expansion of clinical trials will further propel market growth. The increasing focus on treating rare diseases and cancers is also expected to be a key driver for the industry.

Conclusion

Gene therapy is set to transform the healthcare landscape by providing targeted treatments for previously untreatable conditions. While challenges such as high costs and ethical concerns remain, the growing investment in research and technological advancements is positioning the gene therapy market for rapid growth. As more treatments reach commercialization, gene therapy will continue to pave the way for a new era in personalized medicine and healthcare innovation.

For a detailed overview and more insights, you can refer to the full market research report by Mordor Intelligence https://www.mordorintelligence.com/industry-reports/gene-therapy-market  

[tamanna31]

New Trends of Oligonucleotide Synthesis Market with Industry Analysis by 2024 – 2030

Oligonucleotide Synthesis Industry Overview

The global oligonucleotide synthesis market size was estimated at USD 3.68 billion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 13.21% from 2024 to 2030. 

The decreasing prices of sequencing have led to increasing demand for custom-made nucleotides for applications across genetic testing, research, forensics applications, and drug development. This has further boosted the demand for oligonucleotide synthesis. The COVID-19 pandemic has affected every market globally and there has been a surge in the demand for efficient treatment against COVID-19.

Gather more insights about the market drivers, restrains and growth of the Oligonucleotide Synthesis Market

Oligonucleotide therapeutics hold immense potential for treating chronic conditions such as cardiovascular diseases, cancers, and retinal disorders. Emerging new applications of oligo sequences in multiple fields of biotechnology are expected to increase market growth. Demand for molecular diagnostics in precision care is an important emerging application field for oligonucleotide synthesis.

The introduction of advanced techniques such as CRISPR and high-throughput sequencing for gene expression analysis has simplified the genetic screening and modification of genomes. Such innovations are observed to influence the demand for oligonucleotide synthesis. Manufacturers invest in technology development to enable the production of long Oligonucleotides with higher precision and better yield to cater to the growing need for custom oligos.

The availability of a regulatory environment that supports the progress of genomics is the key factor contributing to the market growth. Changes in the regulatory policies to provide a well-framed environment for advanced biological research and application in human use are expected to influence demand for oligonucleotide synthesis significantly. Stem cells, regenerative medicine, genetic engineering, and synthetic biology are the prominent fields identified with high potential in healthcare. For instance, the International Society for Stem Cell Research (ISSCR) ethics and public policy committee aims to recognize and resolve issues by conducting open discussions. The committee includes experts in ethics, law, and social policy worldwide.

Browse through Grand View Research's Biotechnology Industry Research Reports.

The global optical genome mapping market size was valued at USD 104.1 million in 2023 and is expected to grow at a CAGR of 26.76% from 2024 to 2030. 

The global therapeutic drug monitoring market size was valued USD 1.80 billion in 2023 and is projected to grow at a CAGR of 3.8% from 2024 to 2030. 

Key Companies & Market Share Insights

Some of the key players operating in the market include Merck KGaA, Thermo Fisher Scientific, Inc., and Agilent Technologies. These players focus on business strategies such as partnerships/collaborations, product launches, and expansion. Twist Bioscience, Biolegio, and LGC Biosearch Technologies are some of the emerging market participants in the oligonucleotide market. These players primarily focus on expansion and partnerships to strengthen their position in the market.

Key Oligonucleotide Synthesis Companies:

·         Thermo Fisher Scientific, Inc.

·         Merck KGaA

·         Danaher Corporation

·         Dharmacon Inc.

·         Agilent Technologies

·         Bio-synthesis

·         Kaneka Eurogentec S.A

·         LGC Biosearch Technologies

·         Biolegio

·         Twist Bioscience

Recent Developments

In October 2023, IDT inaugurated a new therapeutic manufacturing facility to meet the increasing demand in genomic medicine. The new facility is equipped to support the production of therapeutic oligonucleotides, catering to the expanding needs in the field of genomics and personalized medicine.

In September 2023, Danaher Corporation (Integrated DNA Technologies) introduced a range of xGen NGS products tailored for the Ultima Genomics UG 100TM platform. The suite includes adapters, primers, and universal blockers, catering to various applications such as DNA, RNA, & methylation sequencing workflows. This offering is complemented by IDT's proven hybridization capture chemistry, enhancing versatility for researchers.

In July 2023, Analytix introduced two new instruments designed for organic synthesis, including wavePREP, tailored for oligonucleotide synthesis, and Xelsius, a workstation for multireaction synthesis.

In May 2023, GenScript expanded its life sciences facility in Zhenjiang, Jiangsu, China, to offer a rapid, high-purity oligonucleotide and peptide synthesis service tailored for research & development as well as preclinical applications.

In May 2023, Twist Bioscience and CeGaT GmbH launched the Twist Alliance CeGaT RNA Fusion Panel. This collaborative effort aims to provide a specialized tool for oncology research, facilitating the detection of RNA fusions and enabling transcript variant analysis. RNA fusions, a result of chromosomal arrangements often seen in cancers, can now be efficiently studied using this newly introduced panel.

In February 2023, Fluor Corp. and Agilent Technologies, Inc. collaborated to enhance its oligonucleotide therapeutics manufacturing facility in Frederick, Colorado. Under this collaboration, Fluor is expected to support the project's engineering and procurement. The total value of the project is evaluated at USD 725 million.

Order a free sample PDF of the Oligonucleotide Synthesis Market Intelligence Study, published by Grand View Research.

[industrynewsupdates]

Oligonucleotide Synthesis Market Analysis And Segment Forecast 2024-2030

The global oligonucleotide synthesis market size was estimated at USD 3.68 billion in 2023 and is projected to grow at a compound annual growth rate (CAGR) of 13.21% from 2024 to 2030. 

The decreasing prices of sequencing have led to increasing demand for custom-made nucleotides for applications across genetic testing, research, forensics applications, and drug development. This has further boosted the demand for oligonucleotide synthesis. The COVID-19 pandemic has affected every market globally and there has been a surge in the demand for efficient treatment against COVID-19.

Gather more insights about the market drivers, restrains and growth of the Oligonucleotide Synthesis Market

Oligonucleotide therapeutics hold immense potential for treating chronic conditions such as cardiovascular diseases, cancers, and retinal disorders. Emerging new applications of oligo sequences in multiple fields of biotechnology are expected to increase market growth. Demand for molecular diagnostics in precision care is an important emerging application field for oligonucleotide synthesis.

The introduction of advanced techniques such as CRISPR and high-throughput sequencing for gene expression analysis has simplified the genetic screening and modification of genomes. Such innovations are observed to influence the demand for oligonucleotide synthesis. Manufacturers invest in technology development to enable the production of long Oligonucleotides with higher precision and better yield to cater to the growing need for custom oligos.

The availability of a regulatory environment that supports the progress of genomics is the key factor contributing to the market growth. Changes in the regulatory policies to provide a well-framed environment for advanced biological research and application in human use are expected to influence demand for oligonucleotide synthesis significantly. Stem cells, regenerative medicine, genetic engineering, and synthetic biology are the prominent fields identified with high potential in healthcare. For instance, the International Society for Stem Cell Research (ISSCR) ethics and public policy committee aims to recognize and resolve issues by conducting open discussions. The committee includes experts in ethics, law, and social policy worldwide.

Oligonucleotide Synthesis Market Segmentation

Grand View Research has segmented the global oligonucleotide synthesis market report based on product & service, application, and region:

Product & Service Outlook (Revenue, USD Million, 2018 - 2030)

• Oligonucleotides

o DNA

o Column-based

o Array-based

o RNA

o By Technology

o Column-based

o Array-based

o By Type

o Short RNA Oligos (<65 nt)

o Long RNA Oligos (>65 nt)

o CRISPR (sgRNA)

• Equipment/Synthesizer

• Reagents

• Services

o DNA

o Custom Oligo Synthesis Services

o 25 nmol

o 50 nmol

o 200 nmol

o 1000 nmol

o 10000 nmol

o Modification Services

o Purification Services

o RNA

o Custom Oligo Synthesis Services

o 25 nmol

o 100 nmol

o 1000 nmol

o 10000 nmol

o Modification Services

o Purification Services

Application Outlook (Revenue, USD Million, 2018 - 2030)

• PCR Primers

o Academic Research Institutes

o Diagnostic Laboratories

o Pharmaceutical - Biotechnology Companies

• PCR Assays & Panels

o Academic Research Institutes

o Diagnostic Laboratories

o Pharmaceutical - Biotechnology Companies

• Sequencing

o Academic Research Institutes

o Diagnostic Laboratories

o Pharmaceutical - Biotechnology Companies

• DNA Microarrays

o Academic Research Institutes

o Diagnostic Laboratories

o Pharmaceutical - Biotechnology Companies

• Fluorescence In Situ Hybridization (FISH)

o Academic Research Institutes

o Diagnostic Laboratories

o Pharmaceutical - Biotechnology Companies

• Antisense Oligonucleotides

o Academic Research Institutes

o Diagnostic Laboratories

o Pharmaceutical - Biotechnology Companies

• Other Applications

Regional Outlook (Revenue, USD Million, 2018 - 2030)

• North America

o U.S.

o Canada

• Europe

o Germany

o U.K.

o France

o Spain

o Italy

o Denmark

o Sweden

o Norway

• Asia Pacific

o China

o Japan

o India

o South Korea

o Australia

o Thailand

• Latin America

o Brazil

o Mexico

o Argentina

• Middle East and Africa (MEA)

o South Africa

o Saudi Arabia

o UAE

o Kuwait

Browse through Grand View Research's Biotechnology Industry Research Reports.

• The global optical genome mapping market size was valued at USD 104.1 million in 2023 and is expected to grow at a CAGR of 26.76% from 2024 to 2030. 

• The global therapeutic drug monitoring market size was valued USD 1.80 billion in 2023 and is projected to grow at a CAGR of 3.8% from 2024 to 2030. 

Key Companies & Market Share Insights

Some of the key players operating in the market include Merck KGaA, Thermo Fisher Scientific, Inc., and Agilent Technologies. These players focus on business strategies such as partnerships/collaborations, product launches, and expansion. Twist Bioscience, Biolegio, and LGC Biosearch Technologies are some of the emerging market participants in the oligonucleotide market. These players primarily focus on expansion and partnerships to strengthen their position in the market.

Key Oligonucleotide Synthesis Companies:

• Thermo Fisher Scientific, Inc.

• Merck KGaA

• Danaher Corporation

• Dharmacon Inc.

• Agilent Technologies

• Bio-synthesis

• Kaneka Eurogentec S.A

• LGC Biosearch Technologies

• Biolegio

• Twist Bioscience

Recent Developments

• In October 2023, IDT inaugurated a new therapeutic manufacturing facility to meet the increasing demand in genomic medicine. The new facility is equipped to support the production of therapeutic oligonucleotides, catering to the expanding needs in the field of genomics and personalized medicine.

• In September 2023, Danaher Corporation (Integrated DNA Technologies) introduced a range of xGen NGS products tailored for the Ultima Genomics UG 100TM platform. The suite includes adapters, primers, and universal blockers, catering to various applications such as DNA, RNA, & methylation sequencing workflows. This offering is complemented by IDT's proven hybridization capture chemistry, enhancing versatility for researchers.

• In July 2023, Analytix introduced two new instruments designed for organic synthesis, including wavePREP, tailored for oligonucleotide synthesis, and Xelsius, a workstation for multireaction synthesis.

• In May 2023, GenScript expanded its life sciences facility in Zhenjiang, Jiangsu, China, to offer a rapid, high-purity oligonucleotide and peptide synthesis service tailored for research & development as well as preclinical applications.

• In May 2023, Twist Bioscience and CeGaT GmbH launched the Twist Alliance CeGaT RNA Fusion Panel. This collaborative effort aims to provide a specialized tool for oncology research, facilitating the detection of RNA fusions and enabling transcript variant analysis. RNA fusions, a result of chromosomal arrangements often seen in cancers, can now be efficiently studied using this newly introduced panel.

• In February 2023, Fluor Corp. and Agilent Technologies, Inc. collaborated to enhance its oligonucleotide therapeutics manufacturing facility in Frederick, Colorado. Under this collaboration, Fluor is expected to support the project's engineering and procurement. The total value of the project is evaluated at USD 725 million.

Order a free sample PDF of the Oligonucleotide Synthesis Market Intelligence Study, published by Grand View Research.

[inscinstech]

Bridging the Frontiers of Science: Oligonucleotide Synthesis and Protein Purification

Imagine the potential of manipulating genetic sequences with pinpoint accuracy or isolating a single protein from a myriad of cellular components. These feats, once considered science fiction, are now commonplace in modern laboratories, thanks to advancements in oligonucleotide synthesis and protein purification. These technologies are fundamental to biochemistry and molecular biology, driving innovations in medical research, diagnostics, and therapeutics.

The Science of Oligonucleotide Synthesis

Oligonucleotide synthesis involves creating short sequences of nucleotides, the building blocks of DNA and RNA. These synthetic oligonucleotides are essential tools in genetic research, diagnostics, and therapeutics. By designing specific sequences, scientists can study gene function, develop genetic tests, and create treatments for various diseases.

The process of oligonucleotide synthesis typically involves automated synthesizers that assemble nucleotides in a predetermined order. Each nucleotide is added step-by-step, and the growing chain is protected chemically to prevent unwanted reactions. Once the sequence is complete, the protecting groups are removed, and the oligonucleotide is purified. This high-precision process ensures that the oligonucleotides are accurate and effective for their intended applications.

Applications and Significance of Oligonucleotide Synthesis

The applications of oligonucleotide synthesis are vast and impactful. In research, synthetic oligonucleotides are used in PCR (polymerase chain reaction) to amplify DNA sequences, enabling detailed genetic studies. They are also employed in the development of probes and primers for detecting specific genetic markers associated with diseases. In therapeutics, antisense oligonucleotides can target and modulate gene expression, offering potential treatments for genetic disorders and cancers.

The ability to synthesize oligonucleotides with high accuracy and specificity has revolutionized molecular biology. It allows scientists to explore genetic mechanisms at a granular level, facilitating breakthroughs in understanding disease pathways and developing targeted therapies. The precision of oligonucleotide synthesis is crucial for the success of these applications, underscoring its importance in modern science.

The Art of Protein Purification

Protein purification is the process of isolating a single type of protein from a complex mixture, such as a cell lysate. This process is essential for studying protein structure and function, which are fundamental to virtually every biological process. Purified proteins are used in a wide range of applications, including enzymatic assays, structural biology, and the development of therapeutics.

Applications and Significance of Protein Purification

The ability to isolate pure proteins is crucial for scientific progress. Researchers can study the protein’s role in cellular processes, its interactions with other molecules, and its potential as a drug target. Without protein purification, it would be nearly impossible to conduct these detailed analyses. Purified proteins are also essential for pharmaceutical manufacturing, ensuring that medicines are safe and effective.

In structural biology, purified proteins are used to determine the three-dimensional structures of proteins and protein complexes. This information is vital for understanding how proteins function at a molecular level and for designing drugs that can modulate their activity. In enzymology, purified proteins are used to study enzyme kinetics and mechanisms, providing insights into how enzymes catalyze biochemical reactions. The precision and reliability of protein purification are crucial for these applications, highlighting its importance in research and industry.

Integrating Oligonucleotide Synthesis and Protein Purification

The integration of oligonucleotide synthesis and protein purification in a laboratory setting enhances the capability to conduct advanced biotechnological research. For example, synthesized oligonucleotides can be used to clone and express specific proteins, which are then purified for further study. This combination accelerates the pace of research and development, facilitating the creation of new diagnostics and therapeutics.

Future Prospects and Innovations

The future of oligonucleotide synthesis and protein purification looks promising, with ongoing advancements aimed at increasing efficiency, accuracy, and accessibility. Innovations in automation and digital technology are expected to further streamline these processes, making them more user-friendly and cost-effective. As our understanding of genetics and protein chemistry deepens, these technologies will undoubtedly play a crucial role in the next generation of medical and scientific breakthroughs.

Conclusion

For those interested in exploring the latest advancements in oligonucleotide synthesis and protein purification, Inscinstech.com.cn provides a wealth of information and resources. This platform offers detailed insights into the technologies shaping the future of biotechnology, helping researchers and industry professionals stay informed and competitive. By visiting Inscinstech.com.cn, you can gain access to expert knowledge and tools essential for pioneering work in molecular biology and biochemistry.

Blog Source URL :-

[veliterbio]

The Fate of Oligonucleotide Medications

Oligonucleotide drugs are rapidly gaining a central place in todayÕs pharmaceutical industry. These synthetic molecules of DNA or RNA are meant for selective action on definite genes associated with diseases. This makes oligonucleotide drugs development different from most other drugs, which target proteins or enzymes, because, in principle, one could design drugs that alter genetic activity. This indicates that there can be fresh approaches for managing many disorders, including inherited disorders, cancer, and diabetes.

Advancements in Oligonucleotide Manufacturing

The biggest issue in the oligonucleotide drug development process has been synthesis. The synthesis of good quality oligonucleotides is a process that needs special attention and skill. However, these challenges are being witnessed in the oligonucleotide manufacturing and are deformities, advanced in the synthesis of oligonucleotide have been enabling. The availability of sophisticated instruments enables many oligonucleotide manufacturing companies to be established in the market.

Notably, recent advances in large-scale oligo synthesis make these drugs more readily available to patients. This is a big leap towards increasing the ability to manufacture oligonucleotide drugs at an industrial scale in various parts of the world.

Personalized Medicine and Custom Oligos

Another interesting option for oligonucleotide drugs is individual production of custom oligonucleotide synthesis. This means that therapies can be made according to the patient's genetic structure. HSOs can be synthesized specifically to hit one gene behind a given disease, and this application cannot be had with other drugs.

This ability to develop personalized medicine could, therefore, transform the management of rare genetic ailments among patient populations. As oligo synthesis companies refine their technique, they will develop more targeted treatment services and, therefore, make personalized medicine a possibility.

The Role of Oligo CDMO in Drug Development

Oligo CDMO is a key enabler of these therapies with Contract Development and Manufacturing Organizations. These organizations focus on both the synthesis and production of oligonucleotide drugs, and guide pharmaceutical firms on the challenges of oligonucleotide manufacturing process.

CDMOs contribute to the acceleration of drug development through offering production know-how, quality control and regulatory knowledge. As the consumption of oligonucleotide drugs increases, oligoCDMOs will play an increasingly significant part.

The Future of RNA Oligo Synthesis

Another area of RNA oligo synthesis that we are likely to see much further development is RNA targets. These targets are discussed for potential treatment of cancer, viral disorders, and autoimmune responses. RNA oligonucleotides' effectiveness increases as RNA production advances, and there is hope for treatments as it creates more chances.

As it stands, Rna Synthesis Company are making formidable research efforts toward novel treatment regimens, and the perspective for RNA-based therapies is optimistic. The ability to change RNA directly and regulate the messages converting to proteins can be a good pharmaceutical prospect.

Conclusion

The future for oligonucleotide drugs is bright as we look forward to the future of this platform. As oligo manufacturing has progressed and Oligo CDMOs have entered the scene, these drugs are more available and functional. As the dream of personalized medicine comes to pass, PNA synthesis will provide a molecule that can be adapted to the genetically oriented ailment. Here at Veliter Bio, we are on the cutting edge of this rapidly growing fieldÑoffering the best oligo solutions that will drive the advancement of medicine.

[mysticalpeacenut]

How RNA Leaders Are Shaping Drug Discovery

The landscape of drug discovery is present process a profound transformation, pushed by the revolutionary insights and improvements in RNA studies. RNA, as soon as taken into consideration simply a messenger amongst DNA and proteins, is now recognized as a key participant within the regulation of gene expression and a promising aim for therapeutic intervention. RNA leaders scientists, researchers, and groups at the leading edge of RNA era - are shaping the destiny of drug discovery in tremendous methods. This blog explores how the ones leaders are leveraging RNA centered drug discovery and development to revolutionize medicinal drug.

The Rise of RNA in Drug Discovery

The exploration of RNA as a healing intention has won momentum due to its pivotal role in cell techniques and illness mechanisms. Unlike conventional drug desires that concentrate on proteins, RNA-targeted drug discovery gives a unique technique to modulate gene expression, imparting the capability to deal with a substantial variety of illnesses, along with genetic issues, cancers, and viral infections.

RNA leaders have recognized the untapped capacity of RNA molecules, collectively with messenger RNA (mRNA), small interfering RNA (siRNA), and microRNA (miRNA), in influencing ailment pathways. By focused on RNA, researchers can adjust the manufacturing of sickness-inflicting proteins or restore the expression of useful proteins, starting up new avenues for healing intervention.

Advancements in RNA Targeted Drug Discovery

The journey of RNA centered drug discovery has been marked with the resource of good sized improvements in era and information. Scientists have developed revolutionary strategies to design RNA-centered therapeutics which is probably unique, powerful, and stable. These advancements were driven by RNA leaders who are pioneering research in this exciting problem.

RNA Interference (RNAi): RNAi is a groundbreaking era that permits for the selective silencing of unique genes via targeting their mRNA. This approach has paved the way for the improvement of siRNA-based restoration tactics that may exactly goal sickness-inflicting genes and halt their expression.

Antisense Oligonucleotides (ASOs): ASOs are short, synthetic RNA or DNA molecules that bind to complementary mRNA sequences, preventing the production of dangerous proteins. This generation has proven promise in treating genetic problems and illnesses caused by aberrant gene expression.

MRNA Therapeutics: mRNA therapeutics contain turning in artificial mRNA into cells to provide recuperation proteins. This approach has gained prominence with the development of mRNA-primarily based absolutely vaccines, that have established effective in preventing infectious illnesses like COVID-19.

The Role of RNA Leaders

RNA leaders are at the leading edge of driving innovation and improvement in RNA-targeted drug discovery and development. These visionary scientists and groups are pushing the bounds of what is viable and remodeling the panorama of medicine.

Leading RNA-targeted organizations are making an funding in contemporary-day studies and improvement to carry RNA-based treatment options to the leading edge of healthcare. They are collaborating with academic establishments, biotechnology companies, and pharmaceutical groups to boost up the interpretation of RNA discoveries into feasible therapeutics.

Moreover, RNA leaders are actively worried in organizing and taking element in key occasions such as the RNA Targeted Drug Discovery Summit. These summits offer a platform for specialists to percentage insights, communicate disturbing conditions, and find out opportunities in the area of RNA-centered healing processes. By fostering collaboration and understanding alternate, those sports play a critical position in advancing RNA studies and accelerating drug improvement.

RNA Targeted Drug Development: Impact and Potential

The effect of RNA-focused drug improvement on healthcare is profound. RNA-based therapies have the ability to deal with unmet clinical desires and provide answers for diseases that have been formerly considered untreatable. The versatility of RNA technology allows for the development of remedies which might be tailored to specific affected individual populations, paving the manner for personalised medicinal drug.

RNA-focused treatment options provide several benefits, which include excessive specificity, fast improvement timelines, and the potential to aim a wide kind of ailments. As RNA leaders maintain to broaden the sector, the capability for discovering new treatments and improving affected man or woman results is massive.

Looking Ahead

The future of drug discovery is being shaped by way of manner of the innovative efforts of RNA leaders. As research in RNA biology and therapeutics keeps to evolve, we can count on to see more and more RNA-based totally remedy options engaging in clinical trials and, ultimately, the market. The persisted collaboration amongst academia, enterprise, and regulatory bodies might be important in ensuring the successful translation of RNA discoveries into secure and effective remedies.

Conclusion

RNA leaders are spearheading a trendy technology of drug discovery, pushed through the promise of RNA-focused remedies. Their pioneering efforts in RNA centered drug discovery and development are transforming the landscape of drugs and offering choice for sufferers global. As we appearance to the destiny, the capability of RNA-based absolutely therapeutics to deal with complex illnesses and improve healthcare outcomes is clearly interesting.

To examine greater approximately how RNA-centered generation are shaping the future of medicine, go to Depixus. Explore how our modern solutions are advancing RNA research and using development in drug discovery.

Reposted Blog Post URL: https://petrickzagblogger.wordpress.com/2024/08/09/rna-leaders-are-shaping-drug-discovery/

[globalgrowthinsights]

Annual Wellness Visits (AWV) Software Market Size, Share, Forecast [2032]

Annual Wellness Visits (AWV) Software Market provides in-depth analysis of the market state of Annual Wellness Visits (AWV) Software manufacturers, including best facts and figures, overview, definition, SWOT analysis, expert opinions, and the most current global developments. The research also calculates market size, price, revenue, cost structure, gross margin, sales, and market share, as well as forecasts and growth rates. The report assists in determining the revenue earned by the selling of this report and technology across different application areas.

Geographically, this report is segmented into several key regions, with sales, revenue, market share and growth Rate of Annual Wellness Visits (AWV) Software in these regions till the forecast period

North America

Middle East and Africa

Asia-Pacific

South America

Europe

Key Attentions of Annual Wellness Visits (AWV) Software Market Report:

The report offers a comprehensive and broad perspective on the global Annual Wellness Visits (AWV) Software Market.

The market statistics represented in different Annual Wellness Visits (AWV) Software segments offers complete industry picture.

Market growth drivers, challenges affecting the development of Annual Wellness Visits (AWV) Software are analyzed in detail.

The report will help in the analysis of major competitive market scenario, market dynamics of Annual Wellness Visits (AWV) Software.

Major stakeholders, key companies Annual Wellness Visits (AWV) Software, investment feasibility and new market entrants study is offered.

Development scope of Annual Wellness Visits (AWV) Software in each market segment is covered in this report. The macro and micro-economic factors affecting the Annual Wellness Visits (AWV) Software Market

Advancement is elaborated in this report. The upstream and downstream components of Annual Wellness Visits (AWV) Software and a comprehensive value chain are explained.

Browse More Details On This Report at @https://www.globalgrowthinsights.com/market-reports/annual-wellness-visits-awv-software-market-100557

 Global Growth Insights

Web: https://www.globalgrowthinsights.com

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[biotech-news-feed]

Draft guideline on the development and manufacture of oligonucleotides #BioTech #science

[adityarana1687-blog]

Peptide And Oligonucleotide CDMO Market Is Expected To Witness Higher Demands Till 2030

The global peptide and oligonucleotide CDMO market is expected to reach USD 5.67 billion by 2030, according to a new report by Grand View Research, Inc. , registering a CAGR of 12.5% from 2024 to 2030. The growing recognition of peptides and oligonucleotides as valuable therapeutic agents for various diseases is fueling the demand for CDMO services. Moreover, the increasing pipeline of peptides and oligonucleotide therapeutics and the growing penetration of CDMOs in the field are a few of the factors driving the growth of the market.

The market is fragmented, with several players having similar technological and processing capabilities. These companies offer various services related to peptide and oligonucleotide development, data interpretation, sample analysis, and clinical trial support. The market is characterized by fierce competition driven by factors such as quality assurance, technological advancements, regulatory compliance, and the ability to offer high-value and diverse services.

The growing investment by major companies in the development and manufacturing of peptides and oligonucleotide-based therapeutics is one of the prominent factors supporting the growth of the market. For instance, in September 2023, CordenPharma announced the expansion of its commercial peptide production capabilities through the enhancement of facilities at CordenPharma Colorado, which now stands as the world's largest Solid-Phase Peptide Synthesis (SPPS) manufacturing facility. Additionally, in September 2023, CombiGene selected AmbioPharm as the CDMO partner for their peptide-based pain project, COZY01, which also involves Zyneyro.

The COVID-19 pandemic moderately impacted the market. The early stages of the COVID-19 pandemic had a notable impact on clinical trials, as a result of travel restrictions, disruptions in the supply chain, and setbacks in clinical trials. Nonetheless, it also presented prospects, notably the heightened emphasis on antiviral peptides and the swift creation of mRNA vaccines. Furthermore, there has been a substantial increase in collaborations and partnerships across biopharmaceutical companies with an aim to boost the production of peptide-based therapeutics.

Peptide And Oligonucleotide CDMO Market Report Highlights

The peptides segment accounted for the largest share of 66.3% in 2023.The segment is driven by the growing demand for peptide-based therapeutics and the rise in the number of clinical trials involving the use of peptides.

Based on the service type, the contract manufacturing segment accounted for the largest share of 65.0% in 2023. The substantial market share in this segment primarily results from the growing demand for outsourced manufacturing services, driven by the cost-effectiveness of outsourced manufacturing.

Biopharmaceutical companies are anticipated to witness the highest CAGR of 13.0% across the analysis timeframe due to the increasing number of biopharmaceutical companies focusing on research and development of peptide-based drugs.

Asia Pacific is anticipated to witness the highest CAGR of 13.4% during the forecast time frame. The substantial growth is primarily attributed to the rising trend of Western pharmaceutical companies outsourcing their manufacturing operations to emerging economies like China and India.

Peptide And Oligonucleotide CDMO Market Segmentation

Grand View Research has segmented the global peptide and oligonucleotide CDMO market based on product, service type, end use, and region:

Peptide And Oligonucleotide CDMO Product Outlook (Revenue, USD Million, 2018 - 2030)

Peptides

Oligonucleotides

Peptide And Oligonucleotide CDMO Service Type Outlook (Revenue, USD Million, 2018 - 2030)

Contract Development

Contract Manufacturing

Peptide And Oligonucleotide CDMO End Use Outlook (Revenue, USD Million, 2018 - 2030)

Pharmaceutical Companies

Biopharmaceutical Companies

Others

Peptide And Oligonucleotide CDMO Regional Outlook (Revenue, USD Million, 2018 - 2030)

North America

U.S.                

Canada

Europe

U.K.

Germany

France

Italy

Spain

Denmark

Sweden

Norway

Asia Pacific

Japan

China

India

Australia

South Korea

Thailand

Latin America

Brazil

Mexico

Argentina

Middle East & Africa

South Africa

Saudi Arabia

UAE

Kuwait

List of Key Players in the Peptide And Oligonucleotide CDMO Market

PolyPeptide Group

STA Pharmaceutical Co. Ltd.

Bachem

Creative Peptides

Aurigene Pharmaceutical Services Ltd.

Merck KGaA

EUROAPI

Curia Global, Inc.

CordenPharm

Sylentis, S.A.

[helthcareheven]

Code Masters: DNA Synthesizer Innovations Driving Discovery

The DNA synthesize market has experienced significant growth in the recent years, owing to increased adoption of DNA synthesizers in gene synthesis applications. DNA synthesizers are used to produce both short and long strands of customized DNA through solid-phase phosphoramidite chemical synthesis techniques. Ability of DNA synthesizers to synthesize DNA sequences from scratch has enabled advancements in research and production of therapeutic genes and oligonucleotides. DNA synthesizers offer high specificity and reliability compared to traditional gene synthesis methods. Rising demand for DNA synthesis technologies in molecular diagnostics, genomics, and development of new therapies is a major factor fueling investments in DNA synthesizers globally. The Global DNA Synthesizer Market is estimated to be valued at US$ 4.3 Bn in 2024 and is expected to exhibit a 20 % CAGR over the forecast period 2023 to 2030.

Key Takeaways

Key players operating in the DNA Synthesizer market are Thermo Fisher Scientific, Merck KGaA, Agilent Technologies, Danaher Corporation (Integrated DNA Technologies), GenScript Biotech Corporation, Eurofins Genomics, LGC Limited, BioAutomation Corporation, Bio-Rad Laboratories, Twist Bioscience Corporation, Hamilton Company, New England Biolabs, Nippon Genetics, LGC Biosearch Technologies, DNA Script, Ribbon Biolabs GmbH, and Camena Bioscience. Thermo Fisher Scientific dominates the global DNA synthesizer market with a market share of over 30% and has a strong geographical presence through its Oligo and Gene synthesis business.

The global demand for DNA synthesizers is growing rapidly due to increasing adoption of DNA synthesis techniques in molecular diagnostics, discovery research, and advancement of genome editing technologies. DNA synthesizers are increasingly being used to produce synthetic genes, gene fragments, siRNAs, shRNAs, DNA primers, oligonucleotides and more. Rising research in areas of synthetic biology, cancer genomics and agriculture biotechnology is propelling market growth.

Geographical expansion of key DNA synthesizer manufacturers across regions such as North America, Europe, Asia Pacific and South America is another factor contributing to growth of the global market. Manufacturers are enhancing their global distribution networks and establishing manufacturing facilities in emerging countries to gain higher market share. Increasing collaborations between academic research institutions and DNA synthesizer providers is also expected to support market expansion over the forecast period.

Market drivers Increasing R&D investments in genomics and biotechnology: Growing investments by governments and private organizations in genomics research, drug discovery and precision medicine is one of the key drivers of the DNA synthesizer market. Synthesized DNA is finding increasing use as research models, biomarkers and targets in genomics research. Advancements in genome engineering techniques relying on gene synthesis is further fueling demand.

Development of new gene and vector synthesis applications: Emerging applications of gene synthesis such as development of gene and vector therapeutics, manufacture of oligonucleotides and molecular tools are propelling growth of DNA synthesizer market. Manufacturers are developing new synthesis chemistries, throughput methods and software to enhance utility in these applications. Need for shorter turnaround times and lower costs in application development is driving automation and scalability of DNA synthesizers.

Growing synthetic biology market: Expansion of global synthetic biology market that relies on use of synthesized DNA as foundational blocks is a major growth driver. Rising tools development, workforce expansion and investments are accelerating application scope of synthetic biology, thus supporting DNA synthesizer adoption. Development of CRISPR-Cas9 technology requiring customized DNA and RNA oligos is positively impacting DNA synthesizer sales.

Impact of geopolitical situation on DNA Synthesizer Market growth and future strategies

The current geopolitical tensions have impacted the DNA Synthesizer Market in multiple ways. Supply chain disruptions caused due to the Russia-Ukraine conflict have created delays and increased the costs of raw materials procurement for market players. Transport restrictions implemented between certain countries have also posed challenges in seamless movement of finished products. Furthermore, heightened political risks and economic uncertainties prevailing across some major markets have reduced expenditure on research activities utilizing DNA synthesis technologies by academic institutions and biotech firms.

To cope with these difficulties in the short-run, manufacturers are focusing on developing alternative regional sources for key components and exploring new logistics routes. In the long-run, building flexible manufacturing footprints spanning multiple geographic clusters would help mitigate regional supply chain dependencies. Forming strategic alliances with local players in emerging economies represents another route to circumvent geopolitical barriers and tap into high-potential growth areas. Additionally, intensifying R&D efforts to introduce more automated and affordable benchtop DNA synthesizers can aid wider adoption even during times of constrained research funding.

Geographical regions with high concentration in DNA Synthesizer Market

North America has historically been the dominant regional market for DNA synthesizers, accounting for over 40% of the global revenue. Presence of a large number of well-established life sciences and biopharma companies engaged in advanced research & development activities has sustained the high demand. Additionally, considerable investments by governments and private entities in synthetic biology and genomics domain have propelled the regional market. Europe is another major revenue generating region, supported by presence of various global industry leaders and a robust academic research infrastructure. Continuous technological improvements by domestic players also contribute to its prominent position.

Fastest growing region in the DNA Synthesizer Market

The Asia Pacific region is poised to witness the fastest expansion in the DNA Synthesizer Market over the coming years. This growth can be attributed to increasing R&D expenditures by pharmaceutical companies to accelerate drug discovery initiatives relying on DNA synthesis. Establishment of global research centers by leading organizations and expanding involvement of domestic players are amplifying regional demand. Additionally, growing focus of governments to strengthen synthetic biology and healthcare research through investments and initiatives offers a promising outlook. China, India and other Southeast Asian countries stand to gain significantly owing to their large population base and growing biotechnology industry.

[omkarpatel]

DNA Synthesizer Market is Estimated to Witness High Growth Owing to Increasing Demand for Custom DNA

DNA synthesizers are used for the chemical synthesis of DNA and oligonucleotides in research and diagnostic laboratories. They provide an efficient and cost-effective solution for DNA assembly and custom DNA synthesis for applications in gene editing, genomics, and molecular biology research.                         

Market Dynamics:

The growth of the DNA synthesizer market is driven by the increasing demand for custom DNA due to applications in gene editing and genomics research. CRISPR/Cas9 technology is being widely adopted for gene editing applications and is driving demand for custom DNA. Additionally, growing genomics research for studying genetic mutations and biomarkers of diseases is also fueling market growth. Additionally, technological advancements in DNA synthesis techniques allowing for longer oligo synthesis at lower costs is further supporting market expansion over the forecast period.

DNA Synthesizer Market Drivers

Increasing Applications of DNA in Biotechnology and Pharmaceutical Industry

The growing applications of DNA in biotechnology and pharmaceutical research is one of the major drivers fueling the growth of the global DNA synthesizer market. DNA synthesizers play a vital role in DNA amplification, sequencing and genetic modification which are extensively used in various biotechnology and pharmaceutical applications such as drug discovery, vaccine development, genomics, proteomics, and gene therapy research. According to the World Health Organization, global expenditure on pharmaceutical R&D rose to almost USD 179 billion in 2018 from USD 165 billion in 2017. This rising investment in pharmaceutical R&D is creating strong demand for various DNA technologies including DNA synthesizers.

Advancing Technology and Automation in DNA Synthesizers

Advancements in DNA synthesizer technology and increasing level of automation are positively impacting the market growth. DNA synthesizers with advanced features such as miniaturization, increased throughput, enhanced accuracy and productivity are gaining more popularity among end users. Continuous technological innovations are enabling manufacturers to introduce smaller, more efficient and automated DNA synthesizers. For instance, in 2019, Agilent Technologies launched the next generation nucleotide solution kit and workflow software for DNA synthesis further automating the synthesis process and shortening research cycle times while improving accuracy. Such innovations are expected to further accelerate the adoption of DNA synthesizers.

DNA Synthesizer Market Restrain

High Cost of DNA Synthesizers

The high cost associated with the purchase of DNA synthesizers is a major factor hindering the growth of this market. Due to high precision capabilities and advanced features, DNA synthesizers come at a very high initial purchase price which is a significant barrier, particularly for small and medium research laboratories and institutes with budget constraints. For instance, basic DNA synthesizers with limited features cost anywhere between USD 20,000 to USD 100,000 while advanced DNA synthesizers compatible for automation and high throughput screening may cost over USD 200,000 which is a huge investment for most end users. In emerging economies, limited funding for biomedical and biotechnology research also adversely impacts market development to some extent.

DNA Synthesizer Market Opportunity

Increasing Research Activities in Developing Countries

Developing countries in Asia Pacific and Latin America region are witnessing rising investments in biomedical and biotechnology research from both public and private organizations. This growing focus towards bioscience research in developing nations presents significant growth opportunity for DNA synthesizer market players. Additional funding for life science research, increasing number of collaborations between academic institutions and industry, establishment of bioscience clusters and investment in infrastructure are some of the factors fueling opportunities. Moreover, economic growth in developing countries is enabling improved access to advanced technologies, further driving DNA synthesizers demand for academic and industrial applications. Market players can leverage this opportunity by strengthening their distribution networks and offering favorable financing options in developing markets.

DNA Synthesizer Market Trends

Advent of Cost-Effective Solid-Phase Automated DNA Synthesizers

One of the prominent trends shaping the future of DNA synthesizer market is the emergence of cost-effective solid-phase automated synthesizers. Traditionally, DNA synthesizers based on phosphoramidite chemistry were expensive and required highly skilled professionals for complex programming and operation. However, recent offerings by firms such as Merck KGaA and GenScript are changing market dynamics by introducing affordable benchtop synthesizers compatible for multiple reactions to be performed simultaneously. These new generation solid-phase synthesizers have dramatically reduced the overall cost per base DNA synthesis. Further, their ease of use and touchscreen interfaces eliminate the need for advanced programming skills. This trend of low-cost automated solid-phase synthesizers with simplified workflows is making DNA synthesis more accessible and opening up market opportunity beyond traditional core end users.